| scholarly article | Q13442814 |
| P50 | author | Liudmila Matskova | Q30225119 |
| Gösta Winberg | Q30225122 | ||
| P2093 | author name string | D Rotin | |
| T Pawson | |||
| F Chen | |||
| G Gish | |||
| I Ernberg | |||
| R Ingham | |||
| P Plant | |||
| P2860 | cites work | Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk | Q24303475 |
| The itchy locus encodes a novel ubiquitin protein ligase that is disrupted in a18H mice | Q24308721 | ||
| Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins | Q24310521 | ||
| Characterization of the WW domain of human yes-associated protein and its polyproline-containing ligands | Q24313075 | ||
| The C2 domain of the ubiquitin protein ligase Nedd4 mediates Ca2+-dependent plasma membrane localization | Q24314678 | ||
| The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53 | Q24317677 | ||
| BLNK: a central linker protein in B cell activation | Q24322718 | ||
| Structural basis for Syk tyrosine kinase ubiquity in signal transduction pathways revealed by the crystal structure of its regulatory SH2 domains bound to a dually phosphorylated ITAM peptide | Q24322758 | ||
| The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules | Q24323939 | ||
| Identification of novel human WW domain-containing proteins by cloning of ligand targets | Q24336090 | ||
| Cloning of ligand targets: systematic isolation of SH3 domain-containing proteins | Q24336715 | ||
| Epstein-Barr virus LMP2A-induced B-cell survival in two unique classes of EmuLMP2A transgenic mice | Q24524255 | ||
| FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands | Q24532189 | ||
| Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination | Q24532806 | ||
| Identification of a PY motif in the epithelial Na channel subunits as a target sequence for mutations causing channel activation found in Liddle syndrome | Q24563016 | ||
| WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome | Q24563029 | ||
| An Epstein-Barr virus transformation-associated membrane protein interacts with src family tyrosine kinases | Q24644262 | ||
| Regulation of the Src family tyrosine kinase Blk through E6AP-mediated ubiquitination | Q24656742 | ||
| Structural and functional analysis of the mitotic rotamase Pin1 suggests substrate recognition is phosphorylation dependent | Q27739821 | ||
| Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels | Q27860531 | ||
| BLNK required for coupling Syk to PLC gamma 2 and Rac1-JNK in B cells | Q28137612 | ||
| Identification of a set of genes with developmentally down-regulated expression in the mouse brain | Q28187594 | ||
| Liddle's syndrome: heritable human hypertension caused by mutations in the beta subunit of the epithelial sodium channel | Q28240272 | ||
| Host response to EBV infection in X-linked lymphoproliferative disease results from mutations in an SH2-domain encoding gene | Q28285297 | ||
| Syk tyrosine kinase required for mouse viability and B-cell development | Q28586985 | ||
| Improved retroviral vectors for gene transfer and expression | Q29614384 | ||
| Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade | Q29620459 | ||
| The Epstein-Barr virus latent membrane protein 2A PY motif recruits WW domain-containing ubiquitin-protein ligases | Q30175239 | ||
| Structure of the WW domain of a kinase-associated protein complexed with a proline-rich peptide. | Q30176860 | ||
| Nedd4-like proteins: an emerging family of ubiquitin-protein ligases implicated in diverse cellular functions | Q33632965 | ||
| Tyrosine 112 of latent membrane protein 2A is essential for protein tyrosine kinase loading and regulation of Epstein-Barr virus latency | Q33784647 | ||
| Epithelial cell adhesion to extracellular matrix proteins induces tyrosine phosphorylation of the Epstein-Barr virus latent membrane protein 2: a role for C-terminal Src kinase. | Q33813796 | ||
| Latent membrane protein 1 of Epstein-Barr virus interacts with JAK3 and activates STAT proteins | Q33891012 | ||
| Differences in B cell growth phenotype reflect novel patterns of Epstein-Barr virus latent gene expression in Burkitt's lymphoma cells | Q33929593 | ||
| The (YXXL/I)2 signalling motif found in the cytoplasmic segments of the bovine leukaemia virus envelope protein and Epstein-Barr virus latent membrane protein 2A can elicit early and late lymphocyte activation events | Q34064895 | ||
| Latent membrane protein 1 of Epstein-Barr virus mimics a constitutively active receptor molecule. | Q34250209 | ||
| Identification of latent membrane protein 2A (LMP2A) domains essential for the LMP2A dominant-negative effect on B-lymphocyte surface immunoglobulin signal transduction | Q35868359 | ||
| Epstein-Barr virus latent membrane protein 2 associates with and is a substrate for mitogen-activated protein kinase. | Q35887119 | ||
| A spliced Epstein-Barr virus gene expressed in immortalized lymphocytes is created by circularization of the linear viral genome | Q36344649 | ||
| Ubiquitin-mediated degradation of active Src tyrosine kinase | Q36700739 | ||
| Role of Syk in B-cell development and antigen-receptor signaling | Q37114681 | ||
| Three pathways of Epstein-Barr virus gene activation from EBNA1-positive latency in B lymphocytes | Q40048949 | ||
| Transmembrane signaling by antigen receptors of B and T lymphocytes | Q40444968 | ||
| Epstein-Barr virus: adaptation to a life within the immune system | Q40661947 | ||
| Ubiquitin-dependent degradation of active Src. | Q40925082 | ||
| Caffeine and halothane sensitivity of intracellular Ca2+ release is altered by 15 calcium release channel (ryanodine receptor) mutations associated with malignant hyperthermia and/or central core disease | Q41087094 | ||
| Regulation of Epstein-Barr virus latency by latent membrane protein 2. | Q41125684 | ||
| The complexity of signaling pathways activated by the BCR. | Q41514660 | ||
| Protein tyrosine kinases in thymocyte development | Q41587202 | ||
| WW (WWP) domains: from structure to function | Q41662740 | ||
| Molecular mimicry of the antigen receptor signalling motif by transmembrane proteins of the Epstein-Barr virus and the bovine leukaemia virus. | Q45595386 | ||
| Unique transcription pattern of Epstein-Barr virus (EBV) in EBV-carrying gastric adenocarcinomas: expression of the transforming BARF1 gene | Q45742234 | ||
| The immunoreceptor tyrosine-based activation motif of Epstein-Barr virus LMP2A is essential for blocking BCR-mediated signal transduction | Q45760793 | ||
| Integral membrane protein 2 of Epstein-Barr virus regulates reactivation from latency through dominant negative effects on protein-tyrosine kinases | Q45783522 | ||
| Structure and function of the WW domain. | Q53216103 | ||
| Antigen receptor tail clue. | Q55060334 | ||
| EBV associated malignancies | Q69835833 | ||
| P433 | issue | 22 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Epstein–Barr virus | Q6900 |
| virology | Q7215 | ||
| membrane protein | Q423042 | ||
| protein ubiquitination | Q3547638 | ||
| P304 | page(s) | 8526-35 | |
| P577 | publication date | 2000-11-01 | |
| P1433 | published in | Molecular and Cellular Biology | Q3319478 |
| P1476 | title | Latent membrane protein 2A of Epstein-Barr virus binds WW domain E3 protein-ubiquitin ligases that ubiquitinate B-cell tyrosine kinases | |
| P478 | volume | 20 |
| Q35691568 | A central role for the ring finger protein RNF11 in ubiquitin-mediated proteolysis via interactions with E2s and E3s. |
| Q40411584 | AIP4 restricts transforming growth factor-beta signaling through a ubiquitination-independent mechanism |
| Q37583544 | Accumulation of cytoplasmic beta-catenin and nuclear glycogen synthase kinase 3beta in Epstein-Barr virus-infected cells |
| Q24683297 | Activation of mitogen-activated protein kinase and NF-kappaB pathways by a Kaposi's sarcoma-associated herpesvirus K15 membrane protein |
| Q37460098 | An essential role of ubiquitination in Cbl-mediated negative regulation of the Src-family kinase Fyn. |
| Q40065770 | Arrestin-2 interacts with the ubiquitin-protein isopeptide ligase atrophin-interacting protein 4 and mediates endosomal sorting of the chemokine receptor CXCR4. |
| Q33823359 | Arsenic trioxide inhibits EBV reactivation and promotes cell death in EBV-positive lymphoma cells |
| Q28253459 | Atrophin-1-interacting protein 4/human Itch is a ubiquitin E3 ligase for human enhancer of filamentation 1 in transforming growth factor-beta signaling pathways |
| Q33849076 | C-terminal domain of the Epstein-Barr virus LMP2A membrane protein contains a clustering signal |
| Q35793738 | Cholesterol is critical for Epstein-Barr virus latent membrane protein 2A trafficking and protein stability |
| Q37419861 | Degradation of activated protein kinases by ubiquitination |
| Q40075938 | Degradation of cofilin is regulated by Cbl, AIP4 and Syk resulting in increased migration of LMP2A positive nasopharyngeal carcinoma cells |
| Q35140426 | Enzyme E2 from Chinese white shrimp inhibits replication of white spot syndrome virus and ubiquitinates its RING domain proteins. |
| Q58803477 | Epstein-Barr Virus-Associated Malignancies: Roles of Viral Oncoproteins in Carcinogenesis |
| Q37336691 | Epstein-Barr virus latent membrane protein 2 effects on epithelial acinus development reveal distinct requirements for the PY and YEEA motifs |
| Q24675538 | Epstein-Barr virus latent membrane protein 2A (LMP2A) employs the SLP-65 signaling module |
| Q36890676 | Epstein-Barr virus latent membrane protein 2A activates beta-catenin signaling in epithelial cells. |
| Q39148562 | Epstein-Barr virus latent membrane protein 2A contributes to anoikis resistance through ERK activation |
| Q36141691 | Epstein-Barr virus latent membrane protein 2A is a B-cell receptor mimic and essential for B-cell survival |
| Q36845865 | Epstein-Barr virus latent membrane protein 2A preferentially signals through the Src family kinase Lyn |
| Q36086653 | Epstein-Barr virus latent membrane protein 2A promotes invasion of nasopharyngeal carcinoma cells through ERK/Fra-1-mediated induction of matrix metalloproteinase 9 |
| Q34344427 | Epstein-Barr virus latent membrane protein 2A regulates c-Jun protein through extracellular signal-regulated kinase |
| Q34029669 | Epstein-Barr virus latent membrane protein-2A-induced DeltaNp63alpha expression is associated with impaired epithelial-cell differentiation |
| Q35691576 | Epstein-Barr virus oncogenesis and the ubiquitin-proteasome system. |
| Q35634286 | Epstein-barr virus latent membrane protein 2B (LMP2B) modulates LMP2A activity |
| Q33884407 | Expression Profiling of WSSV ORF 199 and Shrimp Ubiquitin Conjugating Enzyme in WSSV Infected Penaeus monodon |
| Q35683842 | HECT E3 Ubiquitin Ligase Itch Functions as a Novel Negative Regulator of Gli-Similar 3 (Glis3) Transcriptional Activity. |
| Q37529530 | HIV-1 Nef down-modulates C-C and C-X-C chemokine receptors via ubiquitin and ubiquitin-independent mechanism |
| Q36436143 | HIV-1 Nef impairs heterotrimeric G-protein signaling by targeting Gα(i2) for degradation through ubiquitination |
| Q39672120 | Herpes simplex virus UL56 interacts with and regulates the Nedd4-family ubiquitin ligase Itch. |
| Q40708596 | Herpesviral protein targets a cellular WD repeat endosomal protein to downregulate T lymphocyte receptor expression |
| Q43872764 | Heterogeneous expression of Src tyrosine kinases Lyn, Fyn and Syk in classical Hodgkin lymphoma: prognostic implications |
| Q24337193 | Identification of the WW domain-interaction sites in the unstructured N-terminal domain of EBV LMP 2A |
| Q24306305 | Itch/AIP4 mediates Deltex degradation through the formation of K29-linked polyubiquitin chains |
| Q34975783 | Itchy, a Nedd4 Ubiquitin Ligase, Downregulates Latent Membrane Protein 2A Activity in B-Cell Signaling |
| Q39685776 | LMP-1's transmembrane domains encode multiple functions required for LMP-1's efficient signaling |
| Q92907715 | LMP2A induces DNA methylation and expression repression of AQP3 in EBV-associated gastric carcinoma |
| Q38597241 | Latent Membrane Protein 2 (LMP2). |
| Q36607423 | Magnetic resonance imaging and spectroscopy in a mouse model of schizophrenia |
| Q38934480 | Manipulation of ubiquitin/SUMO pathways in human herpesviruses infection |
| Q40120713 | Minimal protein domain requirements for the intracellular localization and self-aggregation of Epstein-Barr virus latent membrane protein 2. |
| Q42180912 | Molecular principles of human virus protein-protein interactions |
| Q38315883 | Multifaceted role of the ubiquitin ligase Itch in immune regulation |
| Q28208259 | Negative regulation of Lck by Cbl ubiquitin ligase |
| Q34282287 | New views of BCR structure and organization. |
| Q92349386 | Novel Synthetic DNA Immunogens Targeting Latent Expressed Antigens of Epstein-Barr Virus Elicit Potent Cellular Responses and Inhibit Tumor Growth |
| Q33842129 | PY motifs of Epstein-Barr virus LMP2A regulate protein stability and phosphorylation of LMP2A-associated proteins |
| Q42616097 | Partial molecular characterization, expression pattern, polymorphism and association analysis of porcine SKP2 gene |
| Q37255907 | Pooled RNAi screen identifies ubiquitin ligase Itch as crucial for influenza A virus release from the endosome during virus entry |
| Q40774508 | Processing of a multiple membrane spanning Epstein-Barr virus protein for CD8(+) T cell recognition reveals a proteasome-dependent, transporter associated with antigen processing-independent pathway |
| Q33883819 | RING-H2 protein WSSV249 from white spot syndrome virus sequesters a shrimp ubiquitin-conjugating enzyme, PvUbc, for viral pathogenesis |
| Q34774645 | Rapamycin reverses splenomegaly and inhibits tumor development in a transgenic model of Epstein-Barr virus-related Burkitt's lymphoma |
| Q92279252 | Regulation of autoimmune disease by the E3 ubiquitin ligase Itch |
| Q31016943 | Rhabdoviruses and the cellular ubiquitin-proteasome system: a budding interaction |
| Q38860330 | Role of the immunoreceptor tyrosine-based activation motif of latent membrane protein 2A (LMP2A) in Epstein-Barr virus LMP2A-induced cell transformation |
| Q33307881 | Role of the ubiquitin system and tumor viruses in AIDS-related cancer |
| Q33781678 | Roles of the ITAM and PY motifs of Epstein-Barr virus latent membrane protein 2A in the inhibition of epithelial cell differentiation and activation of {beta}-catenin signaling |
| Q38926327 | SYK interaction with ITGβ4 suppressed by Epstein-Barr virus LMP2A modulates migration and invasion of nasopharyngeal carcinoma cells |
| Q58721423 | Spleen Tyrosine Kinase Inhibitor TAK-659 Prevents Splenomegaly and Tumor Development in a Murine Model of Epstein-Barr Virus-Associated Lymphoma |
| Q37071059 | Strategies of oncogenic microbes to deal with WW domain-containing oxidoreductase |
| Q24648477 | Structural coupling of SH2-kinase domains links Fes and Abl substrate recognition and kinase activation |
| Q24311751 | Stxbp4 regulates DeltaNp63 stability by suppression of RACK1-dependent degradation |
| Q35078625 | Subversion of B lymphocyte signaling by infectious agents. |
| Q38530613 | The E3 ligase Itch in immune regulation and beyond. |
| Q24299260 | The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4 |
| Q36791340 | The E3 ubiquitin ligase Itch in T cell activation, differentiation, and tolerance |
| Q39174018 | The E3 ubiquitin ligase Itch regulates tumor suppressor protein RASSF5/NORE1 stability in an acetylation-dependent manner |
| Q24312062 | The E3 ubiquitin ligase atrophin interacting protein 4 binds directly to the chemokine receptor CXCR4 via a novel WW domain-mediated interaction |
| Q45428621 | The Epstein-Barr virus protein, latent membrane protein 2A, co-opts tyrosine kinases used by the T cell receptor |
| Q36180722 | The G1 phase E3 ubiquitin ligase TRUSS that gets deregulated in human cancers is a novel substrate of the S-phase E3 ubiquitin ligase Skp2. |
| Q24316916 | The HECT ubiquitin ligase AIP4 regulates the cell surface expression of select TRP channels |
| Q35691527 | The Nedd4 family of E3 ubiquitin ligases: functional diversity within a common modular architecture |
| Q24651192 | The RING-H2 protein RNF11 is overexpressed in breast cancer and is a target of Smurf2 E3 ligase |
| Q40169132 | The Shb signalling scaffold binds to and regulates constitutive signals from the Epstein-Barr virus LMP2A membrane protein |
| Q35956721 | The Syk-binding ubiquitin ligase c-Cbl mediates signaling-dependent B cell receptor ubiquitination and B cell receptor-mediated antigen processing and presentation |
| Q30817391 | The Ubiquitin Ligase Itch and Ubiquitination Regulate BFRF1-Mediated Nuclear Envelope Modification for Epstein-Barr Virus Maturation. |
| Q24299799 | The X protein of hepatitis B virus binds to the F box protein Skp2 and inhibits the ubiquitination and proteasomal degradation of c-Myc |
| Q37400412 | The c-Cbl proto-oncoprotein downregulates EBV LMP2A signaling |
| Q34577080 | The effects of the Epstein-Barr virus latent membrane protein 2A on B cell function |
| Q28366332 | The non-receptor tyrosine kinase Syk is a target of Cbl-mediated ubiquitylation upon B-cell receptor stimulation. |
| Q37274351 | The proapoptotic function of SAP provides a clue to the clinical picture of X-linked lymphoproliferative disease |
| Q24293071 | The ubiquitin-protein ligase Itch regulates p73 stability |
| Q35036590 | The ubiquitin/proteasome system in Epstein-Barr virus latency and associated malignancies. |
| Q39806215 | Three Epstein-Barr virus latency proteins independently promote genomic instability by inducing DNA damage, inhibiting DNA repair and inactivating cell cycle checkpoints |
| Q39997624 | Tyrosine Residues Direct the Ubiquitination and Degradation of the NY-1 Hantavirus G1 Cytoplasmic Tail |
| Q33933120 | Ubiquitination and degradation of Syk and ZAP-70 protein tyrosine kinases in human NK cells upon CD16 engagement. |
| Q37520106 | Ubiquitination, ubiquitin-like modifiers, and deubiquitination in viral infection |
| Q44310046 | Viruses and the 26S proteasome: hacking into destruction |
| Q89947272 | Viruses go modular |
| Q24529906 | WW domains provide a platform for the assembly of multiprotein networks |
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