scholarly article | Q13442814 |
review article | Q7318358 |
P2093 | author name string | Jeffrey L Benovic | |
Shawn K Milano | |||
Catherine A C Moore | |||
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 451-82 | |
P577 | publication date | 2007-01-01 | |
P1433 | published in | Annual Review of Physiology | Q567364 |
P1476 | title | Regulation of receptor trafficking by GRKs and arrestins | |
P478 | volume | 69 |
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Q35733196 | 17β-estradiol signaling and regulation of Sertoli cell function |
Q33617270 | A CDC25 family protein phosphatase gates cargo recognition by the Vps26 retromer subunit |
Q27936217 | A calcineurin-dependent switch controls the trafficking function of α-arrestin Aly1/Art6. |
Q39956855 | A homogeneous enzyme fragment complementation-based beta-arrestin translocation assay for high-throughput screening of G-protein-coupled receptors |
Q89532087 | A kinetic method for measuring agonist efficacy and ligand bias using high resolution biosensors and a kinetic data analysis framework |
Q39103103 | A label-free optical biosensor with microfluidics identifies an intracellular signalling wave mediated through the β(2)-adrenergic receptor |
Q89637920 | A negative-feedback loop maintains optimal chemokine concentrations for directional cell migration |
Q24300454 | A novel GRK2/HDAC6 interaction modulates cell spreading and motility |
Q39603042 | A novel trafficking signal within the HLA-C cytoplasmic tail allows regulated expression upon differentiation of macrophages |
Q38089182 | A perspective on more effective GPCR-targeted drug discovery efforts. |
Q34506992 | A single lys residue on the first intracellular loop modulates the endoplasmic reticulum export and cell-surface expression of α2A-adrenergic receptor |
Q89531733 | A structural basis for how ligand binding site changes can allosterically regulate GPCR signaling and engender functional selectivity |
Q35954036 | A triple arg motif mediates α(2B)-adrenergic receptor interaction with Sec24C/D and export |
Q34076241 | AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release |
Q35632439 | ARF family G proteins and their regulators: roles in membrane transport, development and disease. |
Q35837141 | ARRDC1 as a mediator of microvesicle budding |
Q36003618 | Acute activation of β2-adrenergic receptor regulates focal adhesions through βArrestin2- and p115RhoGEF protein-mediated activation of RhoA. |
Q35562523 | Adaptor protein complex-2 (AP-2) and epsin-1 mediate protease-activated receptor-1 internalization via phosphorylation- and ubiquitination-dependent sorting signals. |
Q42613667 | Agonist activation of the G protein-coupled receptor GPR35 involves transmembrane domain III and is transduced via Gα₁₃ and β-arrestin-2. |
Q57023982 | Airway smooth muscle photorelaxation via opsin receptor activation |
Q97681381 | Analyzing kinetic signaling data for G-protein-coupled receptors |
Q35875489 | Anterograde trafficking of nascent α(2B)-adrenergic receptor: structural basis, roles of small GTPases |
Q34043023 | Application of in utero electroporation of G-protein coupled receptor (GPCR) genes, for subcellular localization of hardly identifiable GPCR in mouse cerebral cortex |
Q50496653 | Arf6 negatively controls the rapid recycling of the β2 adrenergic receptor. |
Q36953762 | Arrestin binds to different phosphorylated regions of the thyrotropin-releasing hormone receptor with distinct functional consequences |
Q38831938 | Arrestin-2 and arrestin-3 differentially modulate locomotor responses and sensitization to amphetamine |
Q33992591 | Arrestin-2 interacts with the endosomal sorting complex required for transport machinery to modulate endosomal sorting of CXCR4 |
Q37336333 | Arrestin2/clathrin interaction is regulated by key N- and C-terminal regions in arrestin2 |
Q41986106 | BNGR-A25L and -A27 are two functional G protein-coupled receptors for CAPA periviscerokinin neuropeptides in the silkworm Bombyx mori |
Q37045440 | Beta-arrestin-mediated signaling in the heart |
Q29616793 | Beta-arrestins and cell signaling |
Q38214613 | Biased signaling of protease-activated receptors |
Q24309529 | Bidirectional regulation of neutrophil migration by mitogen-activated protein kinases |
Q51547929 | C-terminal of human histamine H1 receptors regulates their agonist-induced clathrin-mediated internalization and G-protein signaling. |
Q35106596 | CCR5 conformations are dynamic and modulated by localization, trafficking and G protein association |
Q39597237 | CK2 phosphorylation of an acidic Ser/Thr di-isoleucine motif in the Na+/H+ exchanger NHE5 isoform promotes association with beta-arrestin2 and endocytosis. |
Q24318576 | CNIH4 interacts with newly synthesized GPCR and controls their export from the endoplasmic reticulum |
Q41944437 | CXC chemokine receptor 4 signaling upon co-activation with stromal cell-derived factor-1α and ubiquitin |
Q30541389 | CXCL12-induced monocyte-endothelial interactions promote lymphocyte transmigration across an in vitro blood-brain barrier |
Q42082356 | Cannabinoid CB1 and CB2 Receptor Signaling and Bias |
Q64058913 | Cannabinoid CB1 and CB2 Receptor-Mediated Arrestin Translocation: Species, Subtype, and Agonist-Dependence |
Q30487855 | Cargo-mediated regulation of a rapid Rab4-dependent recycling pathway |
Q40106332 | Changes in G protein-coupled receptor sorting protein affinity regulate postendocytic targeting of G protein-coupled receptors |
Q34762029 | Characteristics of membrane progestin receptor alpha (mPRalpha) and progesterone membrane receptor component 1 (PGMRC1) and their roles in mediating rapid progestin actions |
Q37165951 | Characterization of relaxin receptor (RXFP1) desensitization and internalization in primary human decidual cells and RXFP1-transfected HEK293 cells |
Q34416235 | Chemokine (C-X-C motif) receptor 4 and atypical chemokine receptor 3 regulate vascular α₁-adrenergic receptor function |
Q55235440 | Chemotactic Cues for NOTCH1-Dependent Leukemia. |
Q42263287 | Chronic stress promotes lymphocyte reduction through TLR2 mediated PI3K signaling in a β-arrestin 2 dependent manner |
Q37529047 | Class B β-arrestin2-dependent CCR5 signalosome retention with natural antibodies to CCR5. |
Q64055252 | Concepts of GPCR-controlled navigation in the immune system |
Q30557505 | Conformational biosensors reveal GPCR signalling from endosomes. |
Q30485797 | Constitutive internalization of G protein-coupled receptors and G proteins via clathrin-independent endocytosis |
Q34285721 | Cooperation Between the Septins and the Actomyosin Ring and Role of a Cell-Integrity Pathway During Cell Division in Fission Yeast |
Q45194242 | Coordinate-based co-localization-mediated analysis of arrestin clustering upon stimulation of the C-C chemokine receptor 5 with RANTES/CCL5 analogues |
Q37735949 | Custom-designed proteins as novel therapeutic tools? The case of arrestins |
Q33374405 | Delayed internalization and lack of recycling in a beta2-adrenergic receptor fused to the G protein alpha-subunit |
Q33685883 | Deletion of the distal COOH-terminus of the A2B adenosine receptor switches internalization to an arrestin- and clathrin-independent pathway and inhibits recycling |
Q57099294 | Desensitization of depolarization-mediated contractile pathways does not necessarily regulate receptor-mediated excitation-contraction coupling in longitudinal smooth muscle of guinea pig ileum |
Q36463629 | Desensitization, trafficking, and resensitization of the pituitary thyrotropin-releasing hormone receptor |
Q33961384 | Devil's Claw to suppress appetite--ghrelin receptor modulation potential of a Harpagophytum procumbens root extract |
Q39077634 | Dexamethasone in the presence of desipramine enhances MAPK/ERK1/2 signaling possibly via its interference with β-arrestin |
Q42522747 | Different mechanisms regulate lysophosphatidic acid (LPA)-dependent versus phorbol ester-dependent internalization of the LPA1 receptor |
Q42428997 | Differential effects of allosteric M(1) muscarinic acetylcholine receptor agonists on receptor activation, arrestin 3 recruitment, and receptor downregulation |
Q35166797 | Differential expression of arrestins is a predictor of breast cancer progression and survival |
Q42126128 | Differential regulation of endosomal GPCR/β-arrestin complexes and trafficking by MAPK |
Q34787383 | Differential temporal and spatial regulation of somatostatin receptor phosphorylation and dephosphorylation |
Q34551737 | Distinct conformations of GPCR-β-arrestin complexes mediate desensitization, signaling, and endocytosis |
Q42865771 | Distinct functional outputs of PTEN signalling are controlled by dynamic association with β-arrestins. |
Q28118801 | Distinct roles for β-arrestin2 and arrestin-domain-containing proteins in β2 adrenergic receptor trafficking |
Q36887413 | Divergent modes for cargo-mediated control of clathrin-coated pit dynamics |
Q35585071 | Dual mode of glucagon receptor internalization: role of PKCα, GRKs and β-arrestins |
Q37670366 | Dynamic mass redistribution analysis of endogenous β-adrenergic receptor signaling in neonatal rat cardiac fibroblasts |
Q34803218 | EFR3s are palmitoylated plasma membrane proteins that control responsiveness to G-protein-coupled receptors |
Q34048283 | EGFR variant-mediated invasion by enhanced CXCR4 expression through transcriptional and post-translational mechanisms |
Q39436094 | Endocrinology and the brain: corticotropin-releasing hormone signaling |
Q29616848 | Endocytosis and signalling: intertwining molecular networks |
Q33931244 | Endothelin-converting enzyme 1 and β-arrestins exert spatiotemporal control of substance P-induced inflammatory signals |
Q26798878 | Evidence for the role of corticotropin-releasing factor in major depressive disorder |
Q47163312 | Evolutionary action and structural basis of the allosteric switch controlling β2AR functional selectivity. |
Q27313090 | FYVE-dependent endosomal targeting of an arrestin-related protein in amoeba |
Q38698390 | Feedback regulation of G protein-coupled receptor signaling by GRKs and arrestins. |
Q27333875 | Filamin A-hinge region 1-EGFP: a novel tool for tracking the cellular functions of filamin A in real-time |
Q37638132 | Fine-tuning of GPCR activity by receptor-interacting proteins |
Q39300226 | Fluorescent ligand binding reveals heterogeneous distribution of adrenoceptors and 'cannabinoid-like' receptors in small arteries. |
Q36580782 | Formyl peptide receptor-mediated ERK1/2 activation occurs through G(i) and is not dependent on beta-arrestin1/2. |
Q42117966 | Functional consequences of perturbed CXCL12 signal processing: analyses of immature hematopoiesis in GRK6-deficient mice |
Q35881875 | G Protein-Coupled Receptor Kinase 2 (GRK2) and 5 (GRK5) Exhibit Selective Phosphorylation of the Neurotensin Receptor in Vitro |
Q51090373 | G Protein-Coupled Receptor Kinase 3 and Protein Kinase C Phosphorylate the Distal C-Terminal Tail of the Chemokine Receptor CXCR4 and Mediate Recruitment of β-Arrestin. |
Q36665235 | G Protein-coupled Receptor Biased Agonism |
Q35838936 | G Protein-coupled receptor kinase 5 is localized to centrosomes and regulates cell cycle progression |
Q54642775 | G protein-coupled receptor kinase (GRK) |
Q37167895 | G protein-coupled receptor kinase 2 (GRK2) is localized to centrosomes and mediates epidermal growth factor-promoted centrosomal separation |
Q38307746 | G protein-coupled receptor kinase 2 moderates recruitment of THP-1 cells to the endothelium by limiting histamine-invoked Weibel-Palade body exocytosis. |
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Q36006990 | G protein-coupled receptor kinase 5 phosphorylates nucleophosmin and regulates cell sensitivity to polo-like kinase 1 inhibition |
Q35166206 | G protein-coupled receptor kinase 5 phosphorylation of hip regulates internalization of the chemokine receptor CXCR4 |
Q47069082 | G protein-coupled receptor kinase-2 (GRK-2) regulates serotonin metabolism through the monoamine oxidase AMX-2 in Caenorhabditis elegans |
Q33553460 | G protein-coupled receptor kinase-2 constitutively regulates D2 dopamine receptor expression and signaling independently of receptor phosphorylation |
Q37200868 | G protein-coupled receptor kinase-mediated phosphorylation regulates post-endocytic trafficking of the D2 dopamine receptor. |
Q38834292 | G protein-coupled receptor kinases as regulators of dopamine receptor functions |
Q36914223 | G protein-coupled receptor-promoted trafficking of Gbeta1gamma2 leads to AKT activation at endosomes via a mechanism mediated by Gbeta1gamma2-Rab11a interaction |
Q35662226 | G-Protein Coupled Receptor Kinase 2 Minimally Regulates Melanopsin Activity in Intrinsically Photosensitive Retinal Ganglion Cells |
Q38018652 | G-protein coupled receptor resensitization-appreciating the balancing act of receptor function. |
Q24298167 | G-protein-coupled receptor kinase 5 phosphorylates p53 and inhibits DNA damage-induced apoptosis |
Q37058647 | GPCR monomers and oligomers: it takes all kinds |
Q37141950 | GPCR signaling along the endocytic pathway |
Q28277702 | GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling |
Q47850354 | GRK2/β-arrestin mediates arginine vasopressin-induced cardiac fibroblast proliferation. |
Q36652054 | GRK6 deficiency in mice causes autoimmune disease due to impaired apoptotic cell clearance |
Q46392966 | GRPR antagonist protects from drug-induced liver injury by impairing neutrophil chemotaxis and motility. |
Q48389256 | GSK-3β Interacts with Dopamine D1 Receptor to Regulate Receptor Function: Implication for Prefrontal Cortical D1 Receptor Dysfunction in Schizophrenia. |
Q37781424 | GSK-3β activity and hyperdopamine-dependent behaviors |
Q37439970 | Green light to illuminate signal transduction events. |
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Q37529530 | HIV-1 Nef down-modulates C-C and C-X-C chemokine receptors via ubiquitin and ubiquitin-independent mechanism |
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Q36318886 | Induction of cardiac fibrosis by β-blocker in G protein-independent and G protein-coupled receptor kinase 5/β-arrestin2-dependent Signaling pathways. |
Q36303242 | Inferring the lifetime of endosomal protein complexes by fluorescence recovery after photobleaching |
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Q39898138 | Intracellular trafficking of the human oxytocin receptor: evidence of receptor recycling via a Rab4/Rab5 "short cycle". |
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Q37135949 | Prostaglandin E2 affects T cell responses through modulation of CD46 expression |
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Q35027563 | Regulation of Rho-GEF Rgf3 by the arrestin Art1 in fission yeast cytokinesis |
Q37388772 | Regulation of nuclear factor κB (NF-κB) in the nucleus of cardiomyocytes by G protein-coupled receptor kinase 5 (GRK5). |
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Q36731235 | Selective agonism in somatostatin receptor signaling and regulation |
Q36932111 | Sharpening the edges of understanding the structure/function of the LPA1 receptor: expression in cancer and mechanisms of regulation |
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Q30432989 | Site-specific phosphorylation of CXCR4 is dynamically regulated by multiple kinases and results in differential modulation of CXCR4 signaling |
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Q36735740 | Smoothened determines β-arrestin-mediated removal of the G protein-coupled receptor Gpr161 from the primary cilium |
Q35216414 | Somatostatin receptor biology in neuroendocrine and pituitary tumours: part 1--molecular pathways |
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Q39152899 | Sphingosine 1-Phosphate Receptor 1 Signaling in Mammalian Cells |
Q48324782 | Split luciferase complementation assay for the analysis of G protein-coupled receptor ligand response in Saccharomyces cerevisiae. |
Q27649357 | Structure of Vps26B and mapping of its interaction with the retromer protein complex |
Q27657193 | Structure of an Arrestin2-Clathrin Complex Reveals a Novel Clathrin Binding Domain That Modulates Receptor Trafficking |
Q37332439 | Subcellular trafficking of the TRH receptor: effect of phosphorylation |
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Q24315160 | TLR2-dependent pathway of heterologous down-modulation for the CC chemokine receptors 1, 2, and 5 in human blood monocytes |
Q38186775 | Targeting cell surface trafficking of pain-facilitating receptors to treat chronic pain conditions |
Q36230191 | Targeting delta opioid receptors for pain treatment: drugs in phase I and II clinical development. |
Q28571736 | Targeting of beta-arrestin2 to the centrosome and primary cilium: role in cell proliferation control |
Q38089142 | The A, B, Cs of G-protein-coupled receptor pharmacology in assay development for HTS. |
Q37634891 | The Arf GAP AGAP2 interacts with β-arrestin2 and regulates β2-adrenergic receptor recycling and ERK activation |
Q39775078 | The GIT-PIX complexes regulate the chemotactic response of rat basophilic leukaemia cells |
Q26765437 | The Ins and Outs of Anthrax Toxin |
Q47107303 | The Role of Natural Antibodies to CC Chemokine Receptor 5 in HIV Infection |
Q36562896 | The Role of chemokine receptor CXCR4 in breast cancer metastasis |
Q27865233 | The action and mode of binding of thiazolidinedione ligands at free fatty acid receptor 1 |
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Q37356066 | The carboxy-terminal tail of human cytomegalovirus (HCMV) US28 regulates both chemokine-independent and chemokine-dependent signaling in HCMV-infected cells |
Q39945961 | The carboxyl-terminal PDZ ligand motif of chemokine receptor CXCR2 modulates post-endocytic sorting and cellular chemotaxis |
Q37768803 | The complex G protein-coupled receptor kinase 2 (GRK2) interactome unveils new physiopathological targets |
Q52738410 | The complexities of G-protein-coupled receptor kinase function in Hedgehog signaling. |
Q36944706 | The complications of promiscuity: endocannabinoid action and metabolism |
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Q36000382 | The evolving impact of g protein-coupled receptor kinases in cardiac health and disease |
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Q46965251 | The hydrophobic amino acid cluster at the cytoplasmic end of transmembrane helix III modulates the coupling of the β(1)-adrenergic receptor to G(s). |
Q42781808 | The interplay between G protein-coupled receptor kinase 2 (GRK2) and histone deacetylase 6 (HDAC6) at the crossroads of epithelial cell motility |
Q24292828 | The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells |
Q47952666 | The neuro control of the ovarain cycle - a hypothesis |
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Q40455623 | Tracking cell surface GABAB receptors using an alpha-bungarotoxin tag |
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