| scholarly article | Q13442814 |
| P2093 | author name string | G S Cottrell | |
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| The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor | Q22253381 | ||
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| Protease-activated receptor 3 is a second thrombin receptor in humans | Q24310957 | ||
| Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2 | Q24315023 | ||
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| Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2 | Q24336125 | ||
| Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation | Q24337851 | ||
| Endosomal deubiquitinating enzymes control ubiquitination and down-regulation of protease-activated receptor 2. | Q37460026 | ||
| Mitochondrial reactive oxygen species mediate GPCR-induced TACE/ADAM17-dependent transforming growth factor-alpha shedding | Q37475351 | ||
| New insights into the regulation of angiotensin receptors | Q37476634 | ||
| Mixed inhibitors of angiotensin-converting enzyme (EC 3.4.15.1) and enkephalinase (EC 3.4.24.11): rational design, properties, and potential cardiovascular applications of glycopril and alatriopril | Q37511145 | ||
| Comparative rates of desensitization of beta-adrenergic receptors by the beta-adrenergic receptor kinase and the cyclic AMP-dependent protein kinase | Q37548650 | ||
| Clathrin-coated vesicles contain an ATP-dependent proton pump | Q37605141 | ||
| Inhibition of zinc metallopeptidases in cardiovascular disease--from unity to trinity, or duality? | Q37635221 | ||
| Endothelin--biology and disease | Q37751103 | ||
| Intranuclear translocation signaling of HB-EGF carboxy-terminal fragment and mucosal defense through cell proliferation and migration in digestive tracts. | Q37768619 | ||
| Regulatory functions of ubiquitin in diverse DNA damage responses | Q37845892 | ||
| Ubiquitylation in apoptosis: a post-translational modification at the edge of life and death | Q37893455 | ||
| Specific functions of lysosomal proteases in endocytic and autophagic pathways. | Q37902291 | ||
| Targeting a family B GPCR/RAMP receptor complex: CGRP receptor antagonists and migraine | Q37922799 | ||
| Protease-activated receptor 2 signaling in inflammation | Q37942473 | ||
| Multiple degradation pathways regulate versatile CIP/KIP CDK inhibitors | Q37966332 | ||
| The mouse proteinase-activated receptor-2 cDNA and gene. Molecular cloning and functional expression | Q38297518 | ||
| Alternative, nonapoptotic programmed cell death: mediation by arrestin 2, ERK2, and Nur77. | Q38344927 | ||
| Dual effect of the novel peptide antagonist K-14585 on proteinase-activated receptor-2-mediated signalling. | Q39774017 | ||
| Plasmin potentiates synaptic N-methyl-D-aspartate receptor function in hippocampal neurons through activation of protease-activated receptor-1. | Q40089276 | ||
| GPCR-induced migration of breast carcinoma cells depends on both EGFR signal transactivation and EGFR-independent pathways. | Q40373265 | ||
| Reactive oxygen species-dependent TNF-alpha converting enzyme activation through stimulation of 5-HT2B and alpha1D autoreceptors in neuronal cells | Q40403884 | ||
| G protein coupling and second messenger generation are indispensable for metalloprotease-dependent, heparin-binding epidermal growth factor shedding through angiotensin II type-1 receptor | Q40420092 | ||
| PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumorigenesis of breast cancer cells. | Q40459317 | ||
| Pseudomonas aeruginosa elastase disables proteinase-activated receptor 2 in respiratory epithelial cells. | Q40459581 | ||
| Distinct ADAM metalloproteinases regulate G protein-coupled receptor-induced cell proliferation and survival | Q40520865 | ||
| Proteinase-activated receptor-2 and human lung epithelial cells: disarming by neutrophil serine proteinases. | Q40669694 | ||
| Trafficking patterns of beta-arrestin and G protein-coupled receptors determined by the kinetics of beta-arrestin deubiquitination | Q40672031 | ||
| Glucagon-like peptide 1 induces pancreatic beta-cell proliferation via transactivation of the epidermal growth factor receptor | Q40681109 | ||
| Ubiquitination-independent trafficking of G protein-coupled receptors to lysosomes | Q40694108 | ||
| Agonist-promoted Ubiquitination of the G Protein-coupled Receptor CXCR4 Mediates Lysosomal Sorting | Q40773765 | ||
| Protein kinase C-mediated desensitization of the neurokinin 1 receptor | Q40814998 | ||
| Differential affinities of visual arrestin, beta arrestin1, and beta arrestin2 for G protein-coupled receptors delineate two major classes of receptors | Q40889383 | ||
| Hydrolysis of peptide hormones by endothelin-converting enzyme-1. A comparison with neprilysin | Q40975225 | ||
| Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase. | Q41066099 | ||
| Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors | Q41229236 | ||
| Effect of N-[(S)-1-carboxy-3-phenylpropyl]-L-Ala-L-Pro and its ethyl ester (MK-421) on angiotensin converting enzyme in vitro and angiotensin I pressor responses in vivo | Q41550110 | ||
| Type-specific sorting of G protein-coupled receptors after endocytosis | Q41728938 | ||
| Platelet matrix metalloprotease-1 mediates thrombogenesis by activating PAR1 at a cryptic ligand site | Q42177034 | ||
| A novel mechanism of neurokinin-1 receptor resensitization | Q42527972 | ||
| The metabolism of neuropeptides. The hydrolysis of peptides, including enkephalins, tachykinins and their analogues, by endopeptidase-24.11. | Q42848250 | ||
| Pharmacological characterization of a novel sulfonylureid-pyrazole derivative, SM-19712, a potent nonpeptidic inhibitor of endothelin converting enzyme | Q43508596 | ||
| Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: Metalloproteinase inhibitors as a new therapy | Q43851616 | ||
| Effects of the vasopeptidase inhibitor, omapatrilat, in 723 patients with coronary heart disease | Q44313582 | ||
| Trypsin IV, a novel agonist of protease-activated receptors 2 and 4. | Q44730652 | ||
| Plasmin-mediated activation of platelets occurs by cleavage of protease-activated receptor 4. | Q44770013 | ||
| Ionotropic and metabotropic receptors, protein kinase A, protein kinase C, and Src contribute to C-fiber-induced ERK activation and cAMP response element-binding protein phosphorylation in dorsal horn neurons, leading to central sensitization. | Q45072859 | ||
| Activated protein C mediates novel lung endothelial barrier enhancement: role of sphingosine 1-phosphate receptor transactivation | Q45264873 | ||
| Neurogenic inflammation in the rat trachea. II. Identity and distribution of nerves mediating the increase in vascular permeability | Q46049832 | ||
| Antibodies to protease-activated receptor 3 inhibit activation of mouse platelets by thrombin | Q46095114 | ||
| Neurogenic inflammation in the rat trachea. I. Changes in venules, leucocytes and epithelial cells | Q46229258 | ||
| Extracellular mutations of protease-activated receptor-1 result in differential activation by thrombin and thrombin receptor agonist peptide. | Q46262596 | ||
| Neurokinin-1 receptor resensitization precedes receptor recycling | Q46375416 | ||
| CGS 35601 and its orally active prodrug CGS 37808 as triple inhibitors of endothelin-converting enzyme-1, neutral endopeptidase 24.11, and angiotensin-converting enzyme | Q46444049 | ||
| Functional selectivity of G protein signaling by agonist peptides and thrombin for the protease-activated receptor-1. | Q46477127 | ||
| Triple vasopeptidase inhibition normalizes blood pressure in conscious, unrestrained, and spontaneously hypertensive rats | Q46859152 | ||
| Distribution and biochemical characterization of somatostatin receptors in tumors of the human central nervous system | Q48191088 | ||
| Acute hemodynamic effects of the active metabolite of imidapril, (4S)-3-((2S)-2-[N-((1S)-1-carboxy-3-phenyl-propyl)amino]propionyl)-1- methyl-2-oxoimidazolidine-4-carboxylic acid, and enalaprilat in anesthetized dogs | Q51684940 | ||
| Neutrophil proteases can inactivate human PAR3 and abolish the co-receptor function of PAR3 on murine platelets. | Q55034739 | ||
| Calcitonin gene-related peptide, neurokinin A and substance P: Effects on Nociception and neurogenic inflammation in human skin and temporal muscle | Q57025168 | ||
| Signaling on the endocytic pathway | Q57359903 | ||
| Thrombin Stimulates Phosphorylation of Insulin-like Growth Factor-1 Receptor, Insulin Receptor Substrate-1, and Phospholipase C-γ1 in Rat Aortic Smooth Muscle Cells | Q57908184 | ||
| Antinociception induced in rats by intrathecal administration of antiserum against calcitonin gene-related peptide | Q58450883 | ||
| Initiation of chick cell division by trypsin action at the cell surface | Q59075529 | ||
| Proteolytic Enzymes Initiating Cell Division and Escape from Contact Inhibition of Growth | Q59077465 | ||
| Release from Density Dependent Growth Inhibition by Proteolytic Enzymes | Q59077468 | ||
| Antinociceptive effect of intrathecally administered antiserum against calcitonin gene-related peptide on thermal and mechanical noxious stimuli in experimental hyperalgesic rats | Q60728467 | ||
| Transmembrane action of thrombin initiates chick cell division | Q67446780 | ||
| Somatostatin-receptor imaging in the localization of endocrine tumors | Q68480764 | ||
| Co-existence of substance P and calcitonin gene-related peptide-like immunoreactivities in sensory nerves in relation to cardiovascular and bronchoconstrictor effects of capsaicin | Q69382593 | ||
| Hormone-producing gastrointestinal tumors contain a high density of somatostatin receptors | Q69812057 | ||
| Somatostatin receptors in human endocrine tumors | Q70156764 | ||
| Receptor endocytosis and dendrite reshaping in spinal neurons after somatosensory stimulation | Q71696623 | ||
| Effects of alatriopril, a mixed inhibitor of atriopeptidase and angiotensin I-converting enzyme, on cardiac hypertrophy and hormonal responses in rats with myocardial infarction. Comparison with captopril | Q72070309 | ||
| Convergence of angiotensin II and platelet-derived growth factor receptor signaling cascades in vascular smooth muscle cells | Q72259808 | ||
| Cloning of PAR3 cDNA from human platelets, and human erythroleukemic and human promonocytic cell lines | Q73686559 | ||
| Epidermal growth factor (EGF) receptor-dependent ERK activation by G protein-coupled receptors: a co-culture system for identifying intermediates upstream and downstream of heparin-binding EGF shedding | Q73720739 | ||
| Renal hemodynamic and natriuretic effects of concomitant Angiotensin-converting enzyme and neutral endopeptidase inhibition in men | Q74742307 | ||
| Agonist-induced sorting of human beta2-adrenergic receptors to lysosomes during downregulation | Q77784873 | ||
| Distinct calcium-dependent pathways of epidermal growth factor receptor transactivation and PYK2 tyrosine phosphorylation in PC12 cells | Q78010436 | ||
| Dissociation of beta-arrestin from internalized bradykinin B2 receptor is necessary for receptor recycling and resensitization | Q81918929 | ||
| The first preclinical pharmacotoxicological safety assessment of CGS 35601, a triple vasopeptidase inhibitor, in chronically instrumented, conscious, and unrestrained spontaneously hypertensive rats | Q83364230 | ||
| Triple VPI CGS 35601 reduces high blood pressure in low-renin, high-salt Dahl salt-sensitive rats | Q83895860 | ||
| Molecular cloning of a potential proteinase activated receptor | Q24563694 | ||
| Agonist-promoted Lys63-linked polyubiquitination of the human kappa-opioid receptor is involved in receptor down-regulation | Q24618315 | ||
| MEROPS: the database of proteolytic enzymes, their substrates and inhibitors | Q24623108 | ||
| Ubiquitination regulates proteolytic processing of G protein-coupled receptors after their sorting to lysosomes | Q24657919 | ||
| Desensitization of the isolated beta 2-adrenergic receptor by beta-adrenergic receptor kinase, cAMP-dependent protein kinase, and protein kinase C occurs via distinct molecular mechanisms | Q28181949 | ||
| Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin | Q28190513 | ||
| Agonist-promoted internalization of a ternary complex between calcitonin receptor-like receptor, receptor activity-modifying protein 1 (RAMP1), and beta-arrestin | Q28215231 | ||
| IL-8 promotes cell proliferation and migration through metalloproteinase-cleavage proHB-EGF in human colon carcinoma cells | Q28238135 | ||
| Regulation of receptor trafficking by GRKs and arrestins | Q28268248 | ||
| A dual thrombin receptor system for platelet activation | Q28280578 | ||
| Post-endocytic sorting of calcitonin receptor-like receptor and receptor activity-modifying protein 1 | Q28289037 | ||
| Enkephalinase inhibitors: potential agents for the management of pain | Q28296959 | ||
| Calcitonin gene-related peptide is a potent vasodilator | Q28306967 | ||
| Endosomal proteolysis regulates calcitonin gene-related peptide responses in mesenteric arteries | Q28577195 | ||
| Endothelin-converting enzyme-1 regulates trafficking and signalling of the neurokinin 1 receptor in endosomes of myenteric neurones | Q28579599 | ||
| Endothelin-converting enzyme 1 promotes re-sensitization of neurokinin 1 receptor-dependent neurogenic inflammation | Q28583662 | ||
| Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosis | Q29617390 | ||
| EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF | Q29619098 | ||
| Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients | Q29619542 | ||
| Novel roles for the E3 ubiquitin ligase atrophin-interacting protein 4 and signal transduction adaptor molecule 1 in G protein-coupled receptor signaling. | Q30010172 | ||
| Calcitonin gene-related peptide in migraine: intersection of peripheral inflammation and central modulation. | Q30466408 | ||
| Reactive oxygen species mediate tumor necrosis factor alpha-converting, enzyme-dependent ectodomain shedding induced by phorbol myristate acetate | Q31825884 | ||
| Regulation of endocytic pH by the Na+,K+-ATPase in living cells | Q33831627 | ||
| Neurotensin is a proinflammatory neuropeptide in colonic inflammation | Q33844018 | ||
| Activation of Trk neurotrophin receptors in the absence of neurotrophins | Q33937877 | ||
| The G-protein-coupled receptor phosphatase: a protein phosphatase type 2A with a distinct subcellular distribution and substrate specificity | Q33970712 | ||
| Signal transduction of angiotensin II type 1 receptor through receptor tyrosine kinase | Q34019805 | ||
| Role of thrombin signalling in platelets in haemostasis and thrombosis | Q34090283 | ||
| A Disintegrin and Metalloenzyme (ADAM) 17 Activation Is Regulated by α5β1 Integrin in Kidney Mesangial Cells | Q34193829 | ||
| Roles of ubiquitin signaling in transcription regulation | Q34228028 | ||
| Guide to Receptors and Channels (GRAC), 5th edition | Q34228968 | ||
| Endothelial barrier protection by activated protein C through PAR1-dependent sphingosine 1-phosphate receptor-1 crossactivation | Q34380698 | ||
| Neuropeptide neurotensin stimulates intestinal wound healing following chronic intestinal inflammation | Q34402440 | ||
| Interactions of mast cell tryptase with thrombin receptors and PAR-2. | Q34415372 | ||
| Small Ubiquitin-like Modifier Modification of Arrestin-3 Regulates Receptor Trafficking | Q34537060 | ||
| Ubiquitin Makes Its Mark on Immune Regulation | Q34539820 | ||
| Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure | Q34620874 | ||
| Effects of enalapril on mortality in severe congestive heart failure. Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS). | Q34682919 | ||
| Design of Specific Inhibitors of Angiotensin-Converting Enzyme: New Class of Orally Active Antihypertensive Agents | Q34936463 | ||
| Mitogenic activity of blood components. I. Thrombin and prothrombin | Q35066394 | ||
| Neutrophil elastase acts as a biased agonist for proteinase-activated receptor-2 (PAR2) | Q35107372 | ||
| β-arrestin-mediated receptor trafficking and signal transduction | Q35175384 | ||
| Protein phosphatase 2A mediates resensitization of the neurokinin 1 receptor. | Q35322050 | ||
| Ubiquitination in the First Cytoplasmic Loop of μ-Opioid Receptors Reveals a Hierarchical Mechanism of Lysosomal Down-regulation | Q35562807 | ||
| Metalloprotease-dependent ErbB ligand shedding in mediating EGFR transactivation and vascular remodelling | Q35594158 | ||
| Regulation and function of somatostatin receptors | Q35775361 | ||
| Endothelin-converting enzyme 1 degrades neuropeptides in endosomes to control receptor recycling | Q35880284 | ||
| Endothelin-Converting Enzyme-1 Actions Determine Differential Trafficking and Signaling of Corticotropin-Releasing Factor Receptor 1 at High Agonist Concentrations | Q35891329 | ||
| Neurotensin-induced Proinflammatory Signaling in Human Colonocytes Is Regulated by β-Arrestins and Endothelin-converting Enzyme-1-dependent Endocytosis and Resensitization of Neurotensin Receptor 1 | Q35922475 | ||
| Ubiquitination differentially regulates clathrin-dependent internalization of protease-activated receptor-1 | Q36118471 | ||
| Angiotensin II and vascular inflammation. | Q36140047 | ||
| Shedding light on ADAM metalloproteinases | Q36159565 | ||
| Antiplatelet and Antithrombin Strategies in Acute Coronary Syndrome: State-Of-The-Art Review | Q36302146 | ||
| The metalloprotease Kuzbanian (ADAM10) mediates the transactivation of EGF receptor by G protein-coupled receptors | Q36323845 | ||
| Ubiquitination of beta-arrestin links seven-transmembrane receptor endocytosis and ERK activation | Q36411260 | ||
| ADAMs as mediators of EGF receptor transactivation by G protein-coupled receptors | Q36504484 | ||
| Endothelin-converting enzyme-1 degrades internalized somatostatin-14. | Q36578821 | ||
| Role of Ubiquitination in Endocytic Trafficking of G‐Protein‐Coupled Receptors | Q36763812 | ||
| Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa | Q36968186 | ||
| Proteinase-activated receptor-1 mediates elastase-induced apoptosis of human lung epithelial cells | Q37273851 | ||
| Therapeutic targeting of g-protein coupled receptor-mediated epidermal growth factor receptor transactivation in human glioma brain tumors | Q37320593 | ||
| Basic and translational research on proteinase-activated receptors: implication of proteinase/proteinase-activated receptor in gastrointestinal inflammation | Q37355511 | ||
| Endosomal endothelin-converting enzyme-1: a regulator of beta-arrestin-dependent ERK signaling. | Q37372302 | ||
| Endosomes: a legitimate platform for the signaling train | Q37394435 | ||
| Agonist-biased signaling via proteinase activated receptor-2: differential activation of calcium and mitogen-activated protein kinase pathways. | Q37402789 | ||
| The angiotensin II type 2 (AT2) receptor: an enigmatic seven transmembrane receptor. | Q37410072 | ||
| Leukocyte elastase induces lung epithelial apoptosis via a PAR-1-, NF-kappaB-, and p53-dependent pathway | Q37443240 | ||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | proteolysis | Q33123 |
| G protein-coupled receptor | Q38173 | ||
| P304 | page(s) | 576-590 | |
| P577 | publication date | 2013-02-01 | |
| P1433 | published in | British Journal of Pharmacology | Q919631 |
| P1476 | title | Roles of proteolysis in regulation of GPCR function | |
| P478 | volume | 168 |
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| Q42790508 | The background to this themed issue on neuropeptides |
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