| scholarly article | Q13442814 |
| review article | Q7318358 |
| P356 | DOI | 10.1016/J.BBAPAP.2011.07.003 |
| P698 | PubMed publication ID | 21767668 |
| P50 | author | Thomas Reinheckel | Q56849298 |
| P2093 | author name string | Sabrina Müller | |
| Julia Dennemärker | |||
| P2860 | cites work | Roles of proteasomes, transporter for antigen presentation (TAP), and beta 2-microglobulin in the processing of bacterial or particulate antigens via an alternate class I MHC processing pathway | Q71151636 |
| Extracellular presence of the lysosomal proteinase cathepsin B in rheumatoid synovium and its activity at neutral pH | Q71347962 | ||
| Inhibition of carcinoma cell invasion and liver metastases formation by the cysteine proteinase inhibitor E-64 | Q73135950 | ||
| Negative regulation of epidermal growth factor signaling by selective proteolytic mechanisms in the endosome mediated by cathepsin B | Q73176159 | ||
| Impaired invariant chain degradation and antigen presentation and diminished collagen-induced arthritis in cathepsin S null mice | Q74595052 | ||
| Presentation of the Goodpasture autoantigen requires proteolytic unlocking steps that destroy prominent T cell epitopes | Q79743369 | ||
| A transporter associated with antigen-processing independent vacuolar pathway for the MHC class I-mediated presentation of endogenous transmembrane proteins | Q80427991 | ||
| Functional in vivo imaging of cysteine cathepsin activity in murine model of inflammation | Q82733740 | ||
| Comparative assessment of substrates and activity based probes as tools for non-invasive optical imaging of cysteine protease activity | Q21143754 | ||
| A Toll-like receptor recognizes bacterial DNA | Q24290668 | ||
| Chaperone-mediated autophagy: molecular mechanisms and physiological relevance | Q24300531 | ||
| Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8 | Q24310398 | ||
| Human cathepsin S: chromosomal localization, gene structure, and tissue distribution | Q24310666 | ||
| A receptor for the selective uptake and degradation of proteins by lysosomes | Q24319797 | ||
| Essential role for cathepsin S in MHC class II-associated invariant chain processing and peptide loading | Q24328923 | ||
| Cathepsin A regulates chaperone-mediated autophagy through cleavage of the lysosomal receptor | Q24337837 | ||
| MEROPS: the peptidase database | Q24644757 | ||
| The chaperone-mediated autophagy receptor organizes in dynamic protein complexes at the lysosomal membrane | Q24646454 | ||
| Major histocompatibility complex class II-associated p41 invariant chain fragment is a strong inhibitor of lysosomal cathepsin L | Q24678337 | ||
| Cathepsin V is involved in the degradation of invariant chain in human thymus and is overexpressed in myasthenia gravis | Q24679698 | ||
| Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3 | Q27860854 | ||
| Dendritic cells and the control of immunity | Q27860918 | ||
| Molecular genetics of the LDL receptor gene in familial hypercholesterolemia | Q28207758 | ||
| Endosomal proteolysis of internalized insulin at the C-terminal region of the B chain by cathepsin D | Q28214776 | ||
| Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells | Q28295485 | ||
| Emerging roles for cysteine proteases in human biology | Q28306260 | ||
| The p41 isoform of invariant chain is a chaperone for cathepsin L | Q28345078 | ||
| Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection | Q28588877 | ||
| Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation | Q28590081 | ||
| Cathepsin L deficiency as molecular defect of furless: hyperproliferation of keratinocytes and perturbation of hair follicle cycling | Q28590536 | ||
| A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor | Q28592058 | ||
| Important role of cathepsin S in generating peptides for TAP-independent MHC class I crosspresentation in vivo | Q28595026 | ||
| Lysosomal cysteine and aspartic proteases are heterogeneously expressed and act redundantly to initiate human invariant chain degradation | Q28612372 | ||
| Endosomal aspartic proteinases are required for invariant-chain processing | Q28612976 | ||
| Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus | Q28613227 | ||
| The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor. | Q29347247 | ||
| Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9 | Q29347250 | ||
| Development by self-digestion: molecular mechanisms and biological functions of autophagy | Q29547880 | ||
| Functions of lysosomes | Q29614182 | ||
| Distinct protease requirements for antigen presentation in vitro and in vivo. | Q43158650 | ||
| Critical role for asparagine endopeptidase in endocytic Toll-like receptor signaling in dendritic cells | Q43251440 | ||
| Inhibition of endosomal insulin-like growth factor-I processing by cysteine proteinase inhibitors blocks receptor-mediated functions | Q43560149 | ||
| Decreased intracellular degradation of insulin-like growth factor binding protein-3 in cathepsin L-deficient fibroblasts | Q43860431 | ||
| Destructive processing by asparagine endopeptidase limits presentation of a dominant T cell epitope in MBP. | Q43867716 | ||
| Specific role for cathepsin S in the generation of antigenic peptides in vivo | Q43867816 | ||
| Involvement of two different cell death pathways in retinal atrophy of cathepsin D-deficient mice | Q44391043 | ||
| Cathepsin L is involved in cathepsin D processing and regulation of apoptosis in A549 human lung epithelial cells | Q45023221 | ||
| Macrophages possess both neutral and acidic protease activities toward low density lipoproteins. | Q45985167 | ||
| Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes. | Q46006433 | ||
| Processing of lipoproteins in human monocyte-macrophages | Q46379231 | ||
| Endosomal proteolysis of insulin-like growth factor-I at its C-terminal D-domain by cathepsin B. | Q46624051 | ||
| Inhibitory fragment from the p41 form of invariant chain can regulate activity of cysteine cathepsins in antigen presentation. | Q46686104 | ||
| Cell type-specific functions of the lysosomal protease cathepsin L in the heart | Q46945604 | ||
| Cathepsin D deficiency induces persistent neurodegeneration in the absence of Bax-dependent apoptosis. | Q48266897 | ||
| Human cathepsin L rescues the neurodegeneration and lethality in cathepsin B/L double-deficient mice | Q48445934 | ||
| Selective transport of internalized antigens to the cytosol for MHC class I presentation in dendritic cells | Q50335820 | ||
| Endocytosis targets exogenous material selectively to cathepsin S in live human dendritic cells, while cell-penetrating peptides mediate nonselective transport to cysteine cathepsins. | Q51079297 | ||
| How shall I eat thee? | Q51983235 | ||
| Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis. | Q52584877 | ||
| Pepstatin A-sensitive aspartic proteases in lysosome are involved in degradation of the invariant chain and antigen-processing in antigen presenting cells of mice infected with Leishmania major. | Q54033906 | ||
| Lysosomal, cytoskeletal, and metabolic alterations in cardiomyopathy of cathepsin L knockout mice | Q56993719 | ||
| Cathepsin D deficiency induces lysosomal storage with ceroid lipofuscin in mouse CNS neurons | Q57203231 | ||
| Signaling on the endocytic pathway | Q57359903 | ||
| Endocytosis | Q57374715 | ||
| NOX2 Controls Phagosomal pH to Regulate Antigen Processing during Crosspresentation by Dendritic Cells | Q58007061 | ||
| Transgenic expression of human cathepsin B promotes progression and metastasis of polyoma-middle-T-induced breast cancer in mice | Q59217860 | ||
| NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals | Q29615704 | ||
| Hyperactive Ras in developmental disorders and cancer | Q29616397 | ||
| Endocytosis and molecular sorting | Q29616706 | ||
| Role of endosomal cathepsins in entry mediated by the Ebola virus glycoprotein | Q30439990 | ||
| Grassystatins A-C from marine cyanobacteria, potent cathepsin E inhibitors that reduce antigen presentation | Q30479486 | ||
| A review of COFRADIC techniques targeting protein N-terminal acetylation | Q30872116 | ||
| IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion | Q33612349 | ||
| Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice. | Q33664639 | ||
| Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry | Q33920306 | ||
| Dilated cardiomyopathy in mice deficient for the lysosomal cysteine peptidase cathepsin L. | Q34028619 | ||
| Neuronal loss and brain atrophy in mice lacking cathepsins B and L | Q34030250 | ||
| Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products | Q34102556 | ||
| An alternatively spliced form of the human lysosome-associated membrane protein-2 gene is expressed in a tissue-specific manner | Q34289312 | ||
| Cathepsin G, and not the asparagine-specific endoprotease, controls the processing of myelin basic protein in lysosomes from human B lymphocytes | Q34315269 | ||
| Towards specific functions of lysosomal cysteine peptidases: phenotypes of mice deficient for cathepsin B or cathepsin L. | Q34343810 | ||
| An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation. | Q34485526 | ||
| RGD-dependent binding of procathepsin X to integrin alphavbeta3 mediates cell-adhesive properties | Q34576631 | ||
| Cysteine cathepsins and the cutting edge of cancer invasion | Q34605340 | ||
| Cathepsin D deficiency is associated with a human neurodegenerative disorder | Q34658270 | ||
| Late endosomes derive from early endosomes by maturation | Q34781759 | ||
| Deficiency for the cysteine protease cathepsin L promotes tumor progression in mouse epidermis | Q34859485 | ||
| Deficiency of cathepsin S reduces atherosclerosis in LDL receptor-deficient mice | Q34967612 | ||
| Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function | Q34996827 | ||
| Thyroid functions of mouse cathepsins B, K, and L. | Q35019251 | ||
| Lysosomal cysteine proteases regulate antigen presentation | Q35140806 | ||
| Familial defective apolipoprotein B-100: a single mutation that causes hypercholesterolemia and premature coronary artery disease | Q35604387 | ||
| Proteolytic processing of dynamin by cytoplasmic cathepsin L is a mechanism for proteinuric kidney disease | Q35916157 | ||
| Enhancing immunogenicity by limiting susceptibility to lysosomal proteolysis | Q36228836 | ||
| The lysosomal cysteine proteases in MHC class II antigen presentation | Q36266499 | ||
| Endosomal proteases in antigen presentation | Q36336164 | ||
| Invariant chain controls the activity of extracellular cathepsin L. | Q36371448 | ||
| Analysis of protease activity in live antigen-presenting cells shows regulation of the phagosomal proteolytic contents during dendritic cell activation | Q36376556 | ||
| Cathepsins B and D are dispensable for major histocompatibility complex class II-mediated antigen presentation | Q36475793 | ||
| Cysteine cathepsins: multifunctional enzymes in cancer | Q36600996 | ||
| Emerging roles of cysteine cathepsins in disease and their potential as drug targets. | Q36740577 | ||
| Recent advances in antigen processing and presentation | Q36945533 | ||
| Targeting proteins to distinct subcellular compartments reveals unique requirements for MHC class I and II presentation | Q37363754 | ||
| Expression of the elastolytic cathepsins S and K in human atheroma and regulation of their production in smooth muscle cells | Q37384330 | ||
| Lysosomes as "suicide bags" in cell death: myth or reality? | Q37497722 | ||
| Diverse regulatory roles for lysosomal proteases in the immune response | Q37564269 | ||
| Intracellular toll-like receptors | Q37719951 | ||
| Lysosomal storage disease: revealing lysosomal function and physiology. | Q37739706 | ||
| Specialized roles for cysteine cathepsins in health and disease. | Q37797839 | ||
| CpG motif-independent activation of TLR9 upon endosomal translocation of "natural" phosphodiester DNA. | Q38316638 | ||
| CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation | Q38331783 | ||
| Participation of autophagy in storage of lysosomes in neurons from mouse models of neuronal ceroid-lipofuscinoses (Batten disease). | Q38702180 | ||
| Haematopoietic development and immunological function in the absence of cathepsin D. | Q39251419 | ||
| Receptor-mediated endocytosis: concepts emerging from the LDL receptor system | Q39461911 | ||
| A mutation in the ovine cathepsin D gene causes a congenital lysosomal storage disease with profound neurodegeneration | Q39922868 | ||
| SARS coronavirus, but not human coronavirus NL63, utilizes cathepsin L to infect ACE2-expressing cells | Q40341738 | ||
| Destructive potential of the aspartyl protease cathepsin D in MHC class II-restricted antigen processing. | Q40356474 | ||
| Exon skipping of cathepsin B: mitochondrial targeting of a lysosomal peptidase provokes cell death | Q40533680 | ||
| Functional imaging of proteolysis: stromal and inflammatory cells increase tumor proteolysis | Q40612550 | ||
| Asparagine endopeptidase can initiate the removal of the MHC class II invariant chain chaperone. | Q40653773 | ||
| Cathepsin L and cathepsin B mediate reovirus disassembly in murine fibroblast cells | Q40734800 | ||
| Control of antigen presentation by a single protease cleavage site | Q40882359 | ||
| Cathepsin D deficiency underlies congenital human neuronal ceroid-lipofuscinosis | Q41919650 | ||
| Cathepsin D-like aspartyl protease activity mediates the degradation of tissue-type plasminogen activator/plasminogen activator inhibitor-1 complexes in human monocytes | Q41932591 | ||
| The lysosomal protease cathepsin L is an important regulator of keratinocyte and melanocyte differentiation during hair follicle morphogenesis and cycling | Q42048079 | ||
| The lysosomal cysteine protease cathepsin L regulates keratinocyte proliferation by control of growth factor recycling. | Q42482166 | ||
| Regulation of lamp2a levels in the lysosomal membrane | Q42831940 | ||
| Impaired turnover of autophagolysosomes in cathepsin L deficiency | Q43035133 | ||
| Proteome-wide analysis of protein carboxy termini: C terminomics | Q43043671 | ||
| Expression of human cathepsin L or human cathepsin V in mouse thymus mediates positive selection of T helper cells in cathepsin L knock-out mice | Q43116887 | ||
| Expression and activity profiling of selected cysteine cathepsins and matrix metalloproteinases in synovial fluids from patients with rheumatoid arthritis and osteoarthritis | Q43151758 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | autophagy | Q288322 |
| P304 | page(s) | 34-43 | |
| P577 | publication date | 2011-07-13 | |
| P1433 | published in | Biochimica et Biophysica Acta | Q864239 |
| P1476 | title | Specific functions of lysosomal proteases in endocytic and autophagic pathways | |
| P478 | volume | 1824 |
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| Q37361030 | An intestinal microRNA modulates the homeostatic adaptation to chronic oxidative stress in C. elegans |
| Q38666985 | Autophagy inhibitors |
| Q91943313 | Carbon black nanoparticles induce cell necrosis through lysosomal membrane permeabilization and cause subsequent inflammatory response |
| Q41827502 | Cathepsin B launches an apoptotic exit effort upon cell death-associated disruption of lysosomes |
| Q42912869 | Cathepsin B pulls the emergency brake on cellular necrosis |
| Q37065664 | Cathepsin Protease Controls Copper and Cisplatin Accumulation via Cleavage of the Ctr1 Metal-binding Ectodomain. |
| Q35019204 | Cathepsin inhibition-induced lysosomal dysfunction enhances pancreatic beta-cell apoptosis in high glucose |
| Q38162775 | Cysteine cathepsins in neurological disorders |
| Q36087869 | Differential Impact of Cysteine Cathepsins on Genetic Mouse Models of De novo Carcinogenesis: Cathepsin B as Emerging Therapeutic Target. |
| Q38086763 | Diversity in the origins of proteostasis networks--a driver for protein function in evolution |
| Q55216397 | GAA hydrolyzes lysosomal glycogen |
| Q37285870 | Inflammatory responses in primary muscle cell cultures in Atlantic salmon (Salmo salar). |
| Q39031727 | Inherited diseases caused by mutations in cathepsin protease genes. |
| Q39345888 | Limited and digestive proteolysis: crosstalk between evolutionary conserved pathways. |
| Q45317169 | Lysosomal glycogen catabolism |
| Q27013815 | Lysosomal membrane proteins and their central role in physiology |
| Q35116175 | Lysosomal protein turnover contributes to the acquisition of TGFβ-1 induced invasive properties of mammary cancer cells. |
| Q38128478 | Lysosomal storage diseases--the horizon expands |
| Q38038228 | Modulating macroautophagy: a neuronal perspective |
| Q40470485 | PCSK9-mediated degradation of the LDL receptor generates a 17 kDa C-terminal LDL receptor fragment. |
| Q33631854 | Pathways of antigen processing |
| Q33734766 | Protease Inhibitors in Tick Saliva: The Role of Serpins and Cystatins in Tick-host-Pathogen Interaction. |
| Q30405313 | Protease recognition sites in Bet v 1a are cryptic, explaining its slow processing relevant to its allergenicity. |
| Q92839147 | Proteases facilitate the endosomal escape of porcine epidemic diarrhea virus during entry into host cells |
| Q92226976 | Proteomics quantifies protein expression changes in a model cnidarian colonised by a thermally tolerant but suboptimal symbiont |
| Q38991844 | Reporter assay for endo/lysosomal escape of toxin-based therapeutics |
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| Q93089168 | Spontaneous Isomerization of Long-Lived Proteins Provides a Molecular Mechanism for the Lysosomal Failure Observed in Alzheimer's Disease |
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