| scholarly article | Q13442814 |
| P356 | DOI | 10.1038/EMBOJ.2011.264 |
| P8608 | Fatcat ID | release_e5plsajkffettbvrt7747vcchy |
| P953 | full work available online at | https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1038%2Femboj.2011.264 |
| https://doi.org/10.1038/emboj.2011.264 | ||
| https://europepmc.org/articles/PMC3173792 | ||
| https://europepmc.org/articles/pmc3173792?pdf=render | ||
| https://europepmc.org/articles/PMC3173792?pdf=render | ||
| P932 | PMC publication ID | 3173792 |
| P698 | PubMed publication ID | 21811235 |
| P5875 | ResearchGate publication ID | 51542217 |
| P50 | author | Kazuhiro Iwai | Q64762138 |
| P2093 | author name string | Jixiao Niu | |
| Yuling Shi | |||
| Zhao-Hui Wu | |||
| P2860 | cites work | Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction | Q22001513 |
| Linear ubiquitination prevents inflammation and regulates immune signalling | Q24298581 | ||
| SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex | Q24298605 | ||
| SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis | Q24298626 | ||
| NEMO and RIP1 control cell fate in response to extensive DNA damage via TNF-α feedforward signaling | Q24298750 | ||
| Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress | Q24300945 | ||
| A ubiquitin ligase complex assembles linear polyubiquitin chains | Q24305030 | ||
| Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation | Q24315943 | ||
| Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains | Q24316967 | ||
| NEMO specifically recognizes K63-linked poly-ubiquitin chains through a new bipartite ubiquitin-binding domain | Q24317367 | ||
| The structure of the CYLD USP domain explains its specificity for Lys63-linked polyubiquitin and reveals a B box module | Q24319910 | ||
| Two-sided ubiquitin binding explains specificity of the TAB2 NZF domain | Q24320937 | ||
| Direct activation of protein kinases by unanchored polyubiquitin chains | Q24324679 | ||
| HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex | Q24338233 | ||
| PKC phosphorylation of TRAF2 mediates IKKalpha/beta recruitment and K63-linked polyubiquitination | Q24652618 | ||
| Structural Basis for Recognition of Diubiquitins by NEMO | Q27653619 | ||
| Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation | Q27654230 | ||
| Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by NZF domains of TAB2 and TAB3 | Q27658279 | ||
| TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains | Q28278500 | ||
| Integrating cell-signalling pathways with NF-kappaB and IKK function | Q28280069 | ||
| Signals from within: the DNA-damage-induced NF-kappaB response | Q28291658 | ||
| Shared principles in NF-kappaB signaling | Q29547234 | ||
| Ubiquitin signalling in the NF-kappaB pathway | Q29616322 | ||
| Nonproteolytic functions of ubiquitin in cell signaling | Q29617294 | ||
| Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB. | Q34131747 | ||
| PIDD mediates NF-kappaB activation in response to DNA damage | Q34477303 | ||
| ATM- and NEMO-Dependent ELKS Ubiquitination Coordinates TAK1-Mediated IKK Activation in Response to Genotoxic Stress | Q34620780 | ||
| Linear Ubiquitin Assembly Complex Negatively Regulates RIG-I- and TRIM25-Mediated Type I Interferon Induction | Q34760296 | ||
| Nuclear initiated NF-κB signaling: NEMO and ATM take center stage | Q35347865 | ||
| Nuclear factor-kappaB: its role in health and disease | Q35791198 | ||
| Lingering mysteries of ubiquitin-chain assembly | Q36368593 | ||
| Ubiquitin-mediated activation of TAK1 and IKK. | Q36819396 | ||
| Many faces of NF-kappaB signaling induced by genotoxic stress | Q36868559 | ||
| Deubiquitylation and regulation of the immune response | Q37184075 | ||
| The role of ubiquitin in NF-kappaB regulatory pathways. | Q37505087 | ||
| Linear polyubiquitination: a new regulator of NF-kappaB activation. | Q37526370 | ||
| Regulation of death receptor signaling by the ubiquitin system | Q37628447 | ||
| c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling | Q39626529 | ||
| A nuclear poly(ADP-ribose)-dependent signalosome confers DNA damage-induced IkappaB kinase activation | Q39773986 | ||
| Molecular linkage between the kinase ATM and NF-kappaB signaling in response to genotoxic stimuli | Q40312088 | ||
| A cytosolic ATM/NEMO/RIP1 complex recruits TAK1 to mediate the NF-kappaB and p38 mitogen-activated protein kinase (MAPK)/MAPK-activated protein 2 responses to DNA damage | Q42793623 | ||
| A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation | Q52901092 | ||
| P433 | issue | 18 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | NF-κB | Q411114 |
| genotoxicity | Q1009245 | ||
| protein ubiquitination | Q3547638 | ||
| DNA damage | Q5205747 | ||
| Inhibitor of kappaB kinase gamma | Q14908211 | ||
| Ring finger protein 31 | Q21985151 | ||
| P304 | page(s) | 3741-53 | |
| P577 | publication date | 2011-08-02 | |
| 2011-09-14 | |||
| P1433 | published in | The EMBO Journal | Q1278554 |
| P1476 | title | LUBAC regulates NF-κB activation upon genotoxic stress by promoting linear ubiquitination of NEMO | |
| P478 | volume | 30 |
| Q57018017 | "Toll-free" pathways for production of type I interferons |
| Q41864059 | A genome-wide siRNA screen reveals positive and negative regulators of the NOD2 and NF-κB signaling pathways. |
| Q92459327 | A protein quality control pathway regulated by linear ubiquitination |
| Q40076402 | ATM is required for SOD2 expression and homeostasis within the mammary gland. |
| Q88917618 | An Update on Autoinflammatory Diseases: Relopathies |
| Q38028343 | Atypical ubiquitylation — the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages |
| Q47287938 | Biophysical and biological evaluation of optimized stapled peptide inhibitors of the linear ubiquitin chain assembly complex (LUBAC). |
| Q89982574 | Cross-regulation between LUBAC and caspase-1 modulates cell death and inflammation |
| Q36052395 | DNA damage induces NF-κB-dependent microRNA-21 up-regulation and promotes breast cancer cell invasion |
| Q88337377 | DNA damage-induced nuclear factor-kappa B activation and its roles in cancer progression |
| Q37995692 | DNA damage‐dependent NF‐κB activation: NEMO turns nuclear signaling inside out |
| Q35640534 | Defective nuclear IKKα function in patients with ectodermal dysplasia with immune deficiency |
| Q35135920 | E3 ubiquitin ligase HOIP attenuates apoptotic cell death induced by cisplatin |
| Q37036380 | EGLN3 Inhibition of NF-κB Is Mediated by Prolyl Hydroxylase-Independent Inhibition of IκB Kinase γ Ubiquitination |
| Q37712429 | Essential role of the linear ubiquitin chain assembly complex in lymphoma revealed by rare germline polymorphisms |
| Q46133539 | HIF and HOIL-1L-mediated PKCζ degradation stabilizes plasma membrane Na,K-ATPase to protect against hypoxia-induced lung injury |
| Q35859525 | IPO3-mediated Nonclassical Nuclear Import of NF-κB Essential Modulator (NEMO) Drives DNA Damage-dependent NF-κB Activation |
| Q53203833 | Inactivation of CYLD in intestinal epithelial cells exacerbates colitis-associated colorectal carcinogenesis - a short report |
| Q37350277 | Innate immune-directed NF-κB signaling requires site-specific NEMO ubiquitination |
| Q35971438 | K63-linked ubiquitination in kinase activation and cancer |
| Q34270866 | Kaposi's sarcoma associated herpesvirus encoded viral FLICE inhibitory protein K13 activates NF-κB pathway independent of TRAF6, TAK1 and LUBAC. |
| Q39177871 | Linear polyubiquitin chains: a new modifier involved in NFκB activation and chronic inflammation, including dermatitis. |
| Q39179203 | Linear ubiquitin chain assembly complex coordinates late thymic T-cell differentiation and regulatory T-cell homeostasis |
| Q54171066 | Linear ubiquitin chains: NF-κB signalling, cell death and beyond. |
| Q39265294 | Linear ubiquitin chains: enzymes, mechanisms and biology |
| Q38130801 | Linear ubiquitination-mediated NF- B regulation and its related disorders |
| Q98172163 | Loss of Function Genetic Screen Identifies ATM Kinase as a Positive Regulator of TLR3-Mediated NF-κB Activation |
| Q41218607 | Loss of PIDD limits NF-κB activation and cytokine production but not cell survival or transformation after DNA damage |
| Q38233678 | Met1-linked ubiquitination in immune signalling |
| Q28072740 | Molecular basis for specificity of the Met1-linked polyubiquitin signal |
| Q34670791 | Negative regulation of NF-κB signaling in T lymphocytes by the ubiquitin-specific protease USP34 |
| Q37990496 | No one can whistle a symphony alone – how different ubiquitin linkages cooperate to orchestrate NF-κB activity |
| Q90028929 | Non-proteolytic ubiquitination of OTULIN regulates NF-κB signaling pathway |
| Q35617725 | Optineurin regulates the interferon response in a cell cycle-dependent manner |
| Q38888783 | Oxidative stress shapes breast cancer phenotype through chronic activation of ATM-dependent signaling |
| Q39378487 | Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response |
| Q26828565 | RBR E3 ubiquitin ligases: new structures, new insights, new questions |
| Q54976750 | RIP1 protects melanoma cells from apoptosis induced by BRAF/MEK inhibitors. |
| Q36111622 | RIPK1 regulates survival of human melanoma cells upon endoplasmic reticulum stress through autophagy. |
| Q37447982 | Regulation of Linear Ubiquitin Chain Assembly Complex by Caspase-Mediated Cleavage of RNF31. |
| Q98386383 | Shank-associated RH domain interactor signaling in tumorigenesis |
| Q38779804 | Signaling via the NFκB system. |
| Q27674024 | Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-κB regulation |
| Q38180064 | TAK1 regulates hepatic cell survival and carcinogenesis |
| Q38040025 | TAK1, more than just innate immunity |
| Q28118631 | TRAF Family Member-associated NF-κB Activator (TANK) Inhibits Genotoxic Nuclear Factor κB Activation by Facilitating Deubiquitinase USP10-dependent Deubiquitination of TRAF6 Ligase |
| Q98568662 | TRIM22 activates NF-κB signaling in glioblastoma by accelerating the degradation of IκBα |
| Q42925205 | Target specificity of the E3 ligase LUBAC for ubiquitin and NEMO relies on different minimal requirements. |
| Q41774507 | The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension. |
| Q24321825 | The E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMO |
| Q94563216 | The HOIL-1L ligase modulates immune signalling and cell death via monoubiquitination of LUBAC |
| Q37512362 | The Inhibitor of Apoptosis (IAPs) in Adaptive Response to Cellular Stress |
| Q38728203 | The Linear Ubiquitin Assembly Complex Modulates Latent Membrane Protein 1 Activation of NF-κB and Interferon Regulatory Factor 7. |
| Q64924690 | The Many Roles of Ubiquitin in NF-κB Signaling. |
| Q52323058 | The fructose-2,6-bisphosphatase TIGAR suppresses NF-κB signaling by directly inhibiting the linear ubiquitin assembly complex LUBAC. |
| Q38420434 | The hepatitis C virus protein NS3 suppresses TNF-α-stimulated activation of NF-κB by targeting LUBAC. |
| Q24293633 | The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis |
| Q38530646 | The multifaceted role of the E3 ubiquitin ligase HOIL-1: beyond linear ubiquitination |
| Q33857612 | The regulation of TGF-β/SMAD signaling by protein deubiquitination |
| Q38026746 | Toward an integrative view of Optineurin functions |
| Q38065965 | Transglutaminase 2 and NF-κB: an odd couple that shapes breast cancer phenotype |
| Q24309553 | USP10 inhibits genotoxic NF-κB activation by MCPIP1-facilitated deubiquitination of NEMO |
| Q36670706 | Ubiquitin-dependent regulation of G protein-coupled receptor trafficking and signaling |
| Q39330282 | Ubiquitination in melanoma pathogenesis and treatment. |
| Q26827754 | When Ubiquitin Meets NF-κB: A Trove for Anti-cancer Drug Development |
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