TRAF Family Member-associated NF-κB Activator (TANK) Inhibits Genotoxic Nuclear Factor κB Activation by Facilitating Deubiquitinase USP10-dependent Deubiquitination of TRAF6 Ligase

scientific journal article

TRAF Family Member-associated NF-κB Activator (TANK) Inhibits Genotoxic Nuclear Factor κB Activation by Facilitating Deubiquitinase USP10-dependent Deubiquitination of TRAF6 Ligase is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M115.643767
P3181OpenCitations bibliographic resource ID4088004
P932PMC publication ID4505586
P698PubMed publication ID25861989

P2093author name stringWei Wang
Mingui Fu
Zhao-Hui Wu
Xuan Huang
Hong-Bo Xin
Aimin Xue
P2860cites workTowards a proteome-scale map of the human protein–protein interaction networkQ21735930
NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinaseQ22010870
Genome engineering using the CRISPR-Cas9 systemQ22122027
The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesisQ24293633
OTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitinQ24294696
USP10 regulates p53 localization and stability by deubiquitinating p53Q24296967
Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stressQ24300945
USP10 inhibits genotoxic NF-κB activation by MCPIP1-facilitated deubiquitination of NEMOQ24309553
I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transductionQ24313173
Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chainsQ24316967
LUBAC regulates NF-κB activation upon genotoxic stress by promoting linear ubiquitination of NEMOQ24318791
Induction of a pro-apoptotic ATM-NF-kappaB pathway and its repression by ATR in response to replication stressQ24336239
Beclin1 controls the levels of p53 by regulating the deubiquitination activity of USP10 and USP13Q24338972
Multiplex genome engineering using CRISPR/Cas systemsQ24609428
NF-κB, the first quarter-century: remarkable progress and outstanding questionsQ26822516
When ubiquitin meets NF-κB: a trove for anti-cancer drug developmentQ26827754
Triggering the interferon antiviral response through an IKK-related pathwayQ28191761
Association of the adaptor TANK with the I kappa B kinase (IKK) regulator NEMO connects IKK complexes with IKK epsilon and TBK1 kinasesQ28215547
Modulation of the interferon antiviral response by the TBK1/IKKi adaptor protein TANKQ28290460
Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6Q28584723
Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral responseQ29617083
Crosstalk in NF-κB signaling pathwaysQ29617418
NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activationQ29618715
TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritisQ34020424
MCP-induced protein 1 deubiquitinates TRAF proteins and negatively regulates JNK and NF-kappaB signalingQ34420804
PIDD mediates NF-kappaB activation in response to DNA damageQ34477303
ATM- and NEMO-Dependent ELKS Ubiquitination Coordinates TAK1-Mediated IKK Activation in Response to Genotoxic StressQ34620780
The IκB kinase complex in NF-κB regulation and beyondQ35001723
The TRAF-associated protein TANK facilitates cross-talk within the IkappaB kinase family during Toll-like receptor signalingQ35345969
DNA damage induces NF-κB-dependent microRNA-21 up-regulation and promotes breast cancer cell invasionQ36052395
Nuclear factor-kappaB inhibitors as sensitizers to anticancer drugsQ36085634
TRAF family member-associated NF-κB activator (TANK) is a negative regulator of osteoclastogenesis and bone formationQ36217430
NF-κB-dependent microRNA-125b up-regulation promotes cell survival by targeting p38α upon ultraviolet radiationQ36294827
Return to homeostasis: downregulation of NF-κB responsesQ37902868
DNA damage-dependent NF-κB activation: NEMO turns nuclear signaling inside out.Q37995692
Regulation of cell death and autophagy by IKK and NF-κB: critical mechanisms in immune function and cancerQ37995693
NF-κB induction of the SUMO protease SENP2: A negative feedback loop to attenuate cell survival response to genotoxic stress.Q38392308
USP10 antagonizes c-Myc transcriptional activation through SIRT6 stabilization to suppress tumor formationQ39044223
Novel cross-talk within the IKK family controls innate immunityQ39622962
A nuclear poly(ADP-ribose)-dependent signalosome confers DNA damage-induced IkappaB kinase activationQ39773986
PIASy mediates NEMO sumoylation and NF-kappaB activation in response to genotoxic stress.Q40244068
Molecular linkage between the kinase ATM and NF-kappaB signaling in response to genotoxic stimuliQ40312088
A cytosolic ATM/NEMO/RIP1 complex recruits TAK1 to mediate the NF-kappaB and p38 mitogen-activated protein kinase (MAPK)/MAPK-activated protein 2 responses to DNA damageQ42793623
cIAP1, cIAP2, and XIAP act cooperatively via nonredundant pathways to regulate genotoxic stress-induced nuclear factor-kappaB activationQ46119131
TANK, a co-inducer with TRAF2 of TNF- and CD 40L-mediated NF-kappaB activationQ48064873
A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation.Q52901092
Suppression of LUBAC-mediated linear ubiquitination by a specific interaction between LUBAC and the deubiquitinases CYLD and OTULINQ87160378
P433issue21
P407language of work or nameEnglishQ1860
P921main subjectgenotoxicityQ1009245
Inhibitor of nuclear factor kappa B kinase regulatory subunit gammaQ5971562
NF-κBQ411114
cellular response to DNA damage stimulusQ14818018
Ubiquitin specific peptidase 10Q21106115
Zinc finger CCCH-type containing 12AQ21108146
TRAF family member associated NFKB activatorQ21111498
P304page(s)13372–13385
P577publication date2015-05-22
P1433published inJournal of Biological ChemistryQ867727
P1476titleTRAF Family Member-associated NF-κB Activator (TANK) Inhibits Genotoxic Nuclear Factor κB Activation by Facilitating Deubiquitinase USP10-dependent Deubiquitination of TRAF6 Ligase
P478volume290

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