scholarly article | Q13442814 |
P356 | DOI | 10.1139/Y11-134 |
P698 | PubMed publication ID | 22486776 |
P50 | author | Patrick E. Macdonald | Q74236752 |
P2093 | author name string | Jocelyn E Manning Fox | |
Catherine Hajmrle | |||
P2860 | cites work | In vitro SUMO-1 modification requires two enzymatic steps, E1 and E2 | Q22008717 |
Identification of the enzyme required for activation of the small ubiquitin-like protein SUMO-1 | Q22009137 | ||
SUMOylation regulates Kv2.1 and modulates pancreatic beta-cell excitability | Q24311712 | ||
Modification with SUMO. A role in transcriptional regulation | Q24534589 | ||
Control of NF-kappa B transcriptional activation by signal induced proteolysis of I kappa B alpha | Q24676497 | ||
Structural basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin-conjugating enzyme Ubc9 and RanGAP1 | Q27637899 | ||
Molecular basis of the redox regulation of SUMO proteases: a protective mechanism of intermolecular disulfide linkage against irreversible sulfhydryl oxidation | Q27647348 | ||
Triggering and amplifying pathways of regulation of insulin secretion by glucose | Q27863677 | ||
Characterization of a family of nucleolar SUMO-specific proteases with preference for SUMO-2 or SUMO-3. | Q27863917 | ||
Sumoylation regulates diverse biological processes | Q27865196 | ||
The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer | Q27933072 | ||
UBL1, a human ubiquitin-like protein associating with human RAD51/RAD52 proteins | Q28115876 | ||
Functional heterogeneity of small ubiquitin-related protein modifiers SUMO-1 versus SUMO-2/3 | Q28145507 | ||
A 212-kb region on chromosome 6q25 containing the TAB2 gene is associated with susceptibility to type 1 diabetes | Q28268724 | ||
A proline-90 residue unique to SUMO-4 prevents maturation and sumoylation | Q28274983 | ||
Genetic and functional evidence supporting SUMO4 as a type 1 diabetes susceptibility gene | Q28275898 | ||
SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation | Q28282094 | ||
SUMOylation regulates kainate-receptor-mediated synaptic transmission | Q28576922 | ||
Pancreas duodenum homeobox-1 transcriptional activation requires interactions with p300 | Q28584322 | ||
Kv2.1 ablation alters glucose-induced islet electrical activity, enhancing insulin secretion | Q28588570 | ||
Myosin Va transports dense core secretory vesicles in pancreatic MIN6 beta-cells | Q28589310 | ||
SUMO-1 conjugation in vivo requires both a consensus modification motif and nuclear targeting | Q29619527 | ||
Nuclear and unclear functions of SUMO | Q29903594 | ||
Monitoring of exocytosis and endocytosis of insulin secretory granules in the pancreatic beta-cell line MIN6 using pH-sensitive green fluorescent protein (pHluorin) and confocal laser microscopy | Q31043443 | ||
The importance of the beta-cell in the pathogenesis of type 2 diabetes mellitus | Q33891620 | ||
SUMO4 and its role in type 1 diabetes pathogenesis | Q34008085 | ||
Members of the Kv1 and Kv2 voltage-dependent K(+) channel families regulate insulin secretion | Q34084555 | ||
Cloning and expression of human homolog HSMT3 to yeast SMT3 suppressor of MIF2 mutations in a centromere protein gene | Q34379548 | ||
Sumoylation silences the plasma membrane leak K+ channel K2P1. | Q34410181 | ||
Lack of cholesterol mobilization in islets of hormone-sensitive lipase deficient mice impairs insulin secretion | Q34657196 | ||
SUMO modification of cell surface Kv2.1 potassium channels regulates the activity of rat hippocampal neurons | Q34865655 | ||
Beta-cell dysfunction and insulin resistance in type 2 diabetes: role of metabolic and genetic abnormalities | Q34996991 | ||
Insulin granule dynamics in pancreatic beta cells | Q35184211 | ||
Evidence that glucose can control insulin release independently from its action on ATP-sensitive K+ channels in mouse B cells | Q35601028 | ||
SUMO modification regulates inactivation of the voltage-gated potassium channel Kv1.5. | Q35629481 | ||
SUMO: a regulator of gene expression and genome integrity. | Q35691533 | ||
Molecular defects in insulin secretion in type-2 diabetes | Q35711972 | ||
Glucose-sensing mechanisms in pancreatic beta-cells. | Q36328341 | ||
Insulin vesicle release: walk, kiss, pause ... then run. | Q36484264 | ||
Emerging role of SUMO in pancreatic beta-cells | Q36936894 | ||
SNAREing voltage-gated K+ and ATP-sensitive K+ channels: tuning beta-cell excitability with syntaxin-1A and other exocytotic proteins | Q36945339 | ||
Core proteins of the secretory machinery | Q37026698 | ||
DeSUMOylating enzymes--SENPs | Q37230112 | ||
Type 2 diabetes: new genes, new understanding | Q37308665 | ||
SUMOylation and De-SUMOylation: wrestling with life's processes | Q37325310 | ||
The SUMO system: an overview | Q37357956 | ||
Emerging roles of desumoylating enzymes | Q37375239 | ||
SUMO proteases: redox regulation and biological consequences | Q37383353 | ||
Sumoylation regulates the transcriptional activity of MafA in pancreatic beta cells | Q38358697 | ||
Site of docking and fusion of insulin secretory granules in live MIN6 beta cells analyzed by TAT-conjugated anti-syntaxin 1 antibody and total internal reflection fluorescence microscopy | Q40607328 | ||
SUMO-1: wrestling with a new ubiquitin-related modifier. | Q41633111 | ||
SUMOylation regulates insulin exocytosis downstream of secretory granule docking in rodents and humans. | Q41863831 | ||
Is a new immune response mediator in the NF-kappaB pathway--SUMO-4--related to type 1 diabetes? | Q42976544 | ||
Inhibition of Kv2.1 voltage-dependent K+ channels in pancreatic beta-cells enhances glucose-dependent insulin secretion. | Q44149480 | ||
Sumoylation of Pdx1 is associated with its nuclear localization and insulin gene activation | Q44253301 | ||
Glucose regulates the cortical actin network through modulation of Cdc42 cycling to stimulate insulin secretion | Q44449615 | ||
Glucose regulation of insulin gene expression requires the recruitment of p300 by the beta-cell-specific transcription factor Pdx-1. | Q44912946 | ||
Insulin secretion is highly sensitive to desorption of plasma membrane cholesterol. | Q46355168 | ||
Delayed-rectifier (KV2.1) regulation of pancreatic beta-cell calcium responses to glucose: inhibitor specificity and modeling | Q46598381 | ||
The SUMO protease SENP5 is required to maintain mitochondrial morphology and function | Q56907347 | ||
P433 | issue | 6 | |
P304 | page(s) | 765-770 | |
P577 | publication date | 2012-04-09 | |
P1433 | published in | Canadian Journal of Physiology and Pharmacology | Q5030248 |
P1476 | title | Novel roles of SUMO in pancreatic β-cells: thinking outside the nucleus | |
P478 | volume | 90 |
Q42739736 | How do reducing equivalents increase insulin secretion? |
Q36165625 | Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells |
Q34295237 | Neuronal SUMOylation: mechanisms, physiology, and roles in neuronal dysfunction |
Q88035512 | SUMO1 enhances cAMP-dependent exocytosis and glucagon secretion from pancreatic α-cells |
Q36635942 | SUMOylation of pancreatic glucokinase regulates its cellular stability and activity |
Q34356005 | SUMOylation protects against IL-1β-induced apoptosis in INS-1 832/13 cells and human islets. |
Q38961119 | Sumoylation Modulates the Susceptibility to Type 1 Diabetes. |
Q39136006 | The Roles of SUMO in Metabolic Regulation |
Q40332996 | Viral Interplay with the Host Sumoylation System |
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