Phospholipase C-delta1 contains a functional nuclear export signal sequence

scientific article published on October 1999

Phospholipase C-delta1 contains a functional nuclear export signal sequence is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.274.40.28537
P698PubMed publication ID10497218
P5875ResearchGate publication ID12803500

P2093author name stringFujii M
Hirata H
Yagisawa H
Kamata H
Yamaga M
P2860cites workCrystal structure of a mammalian phosphoinositide-specific phospholipase C deltaQ27732615
A ternary metal binding site in the C2 domain of phosphoinositide-specific phospholipase C-delta1Q27734937
Regulation of polyphosphoinositide-specific phospholipase C activity by purified Gq.Q27865214
Genetic and biochemical characterization of a phosphatidylinositol-specific phospholipase C in Saccharomyces cerevisiaeQ27936464
The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAsQ28131708
Regulation of phosphoinositide-specific phospholipase C isozymesQ28240477
Regulation of eukaryotic phosphatidylinositol-specific phospholipase C and phospholipase DQ28245266
Inositol trisphosphate and calcium signallingQ28262867
Nucleocytoplasmic transportQ28275907
Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1Q28277890
Catalysis by phospholipase C delta1 requires that Ca2+ bind to the catalytic domain, but not the C2 domainQ28573172
Molecular cloning, splice variants, expression, and purification of phospholipase C-delta 4Q28573932
Identification of a signal for rapid export of proteins from the nucleusQ29547742
Nucleocytoplasmic transport: signals, mechanisms and regulationQ29547904
Rapid isolation of high molecular weight plant DNAQ29617508
Leptomycin B is an inhibitor of nuclear export: inhibition of nucleo-cytoplasmic translocation of the human immunodeficiency virus type 1 (HIV-1) Rev protein and Rev-dependent mRNAQ29620175
Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase CQ29620247
Effects of leptomycin B on the cell cycle of fibroblasts and fission yeast cellsQ34299989
A gene encoding a phosphatidylinositol-specific phospholipase C is induced by dehydration and salt stress in Arabidopsis thaliana.Q34391145
Studies of inositol phospholipid-specific phospholipase C.Q34448929
The putative phosphoinositide-specific phospholipase C gene, PLC1, of the yeast Saccharomyces cerevisiae is important for cell growthQ36132888
Visualization of phosphoinositides that bind pleckstrin homology domains: calcium- and agonist-induced dynamic changes and relationship to myo-[3H]inositol-labeled phosphoinositide poolsQ36255578
Cloning and sequence of multiple forms of phospholipase CQ36453476
Protein sequence requirements for function of the human T-cell leukemia virus type 1 Rex nuclear export signal delineated by a novel in vivo randomization-selection assayQ36561338
Characterization of the nuclear export signal of human T-cell lymphotropic virus type 1 Rex reveals that nuclear export is mediated by position-variable hydrophobic interactionsQ36562395
Characterization of a plasma membrane-associated phosphoinositide-specific phospholipase C from soybeanQ36680326
A new phospholipase C delta 4 is induced at S-phase of the cell cycle and appears in the nucleusQ36790001
Real-time visualization of PH domain-dependent translocation of phospholipase C-delta1 in renal epithelial cells (MDCK): response to hypo-osmotic stressQ40978081
Replacements of single basic amino acids in the pleckstrin homology domain of phospholipase C-delta1 alter the ligand binding, phospholipase activity, and interaction with the plasma membraneQ41067682
Phospholipase C delta 1 requires a pleckstrin homology domain for interaction with the plasma membraneQ41259211
Identification of PI-PLC beta 1, gamma 1, and delta 1 in rat liver: subcellular distribution and relationship to inositol lipid nuclear signalling.Q41634279
Nucleocytoplasmic transport: the last 200 nanometersQ41708889
Changes in nuclear inositol phospholipids induced in intact cells by insulin-like growth factor I.Q42799432
Nuclear localization and signalling activity of phosphoinositidase C beta in Swiss 3T3 cellsQ42818004
Nuclear diacylglycerol produced by phosphoinositide-specific phospholipase C is responsible for nuclear translocation of protein kinase C-alpha.Q42825155
Synthesis of polyphosphoinositides in nuclei of Friend cells. Evidence for polyphosphoinositide metabolism inside the nucleus which changes with cell differentiationQ42857336
Regulation of Phospholipase C-γ1 by Profilin and Tyrosine PhosphorylationQ43486850
Activation of the β1 isozyme of phospholipase C by α subunits of the Gq class of G proteinsQ43736623
Increase of the Catalytic Activity of Phospholipase C-γ1 by Tyrosine PhosphorylationQ44763188
A second gene product of the inositol-phospholipid-specific phospholipase C delta subclassQ45014632
Cytoplasmic localization of mitogen-activated protein kinase kinase directed by its NH2-terminal, leucine-rich short amino acid sequence, which acts as a nuclear export signalQ45300833
Intranuclear translocation of phospholipase C beta2 during HL-60 myeloid differentiation.Q51102415
Phospholipase C Isoforms δ1and δ3from Human FibroblastsQ55879966
P433issue40
P407language of work or nameEnglishQ1860
P304page(s)28537-28541
P577publication date1999-10-01
P1433published inJournal of Biological ChemistryQ867727
P1476titlePhospholipase C-delta1 contains a functional nuclear export signal sequence
P478volume274

Reverse relations

cites work (P2860)
Q27940313Asr1p, a novel yeast ring/PHD finger protein, signals alcohol stress to the nucleus
Q34739523Biochemical and genetic evidence for the presence of multiple phosphatidylinositol- and phosphatidylinositol 4,5-bisphosphate-specific phospholipases C in Tetrahymena
Q47824626Ca2+ oscillation-inducing phospholipase C zeta expressed in mouse eggs is accumulated to the pronucleus during egg activation.
Q40701814Carboxyl-terminal basic amino acids in the X domain are essential for the nuclear import of phospholipase C delta1.
Q28202272Cellular localisation and nuclear export of the human bZIP transcription factor TCF11
Q53501571Combination of a spinning disc confocal unit with frequency-domain fluorescence lifetime imaging microscopy.
Q28580253Identification of nuclear import and export signals within the structure of the zinc finger protein TIS11
Q33289840Identification of two GTP-independent alternatively spliced forms of tissue transglutaminase in human leukocytes, vascular smooth muscle, and endothelial cells
Q24338619Interphase nucleo-cytoplasmic shuttling and localization of SIRT2 during mitosis
Q24296290Nuclear accumulation of calcineurin B homologous protein 2 (CHP2) results in enhanced proliferation of tumor cells
Q31685709Nuclear import and export signals enable rapid nucleocytoplasmic shuttling of the atypical protein kinase C lambda
Q38124473Nuclear inositide specific phospholipase C signalling - interactions and activity
Q34268750Nuclear inositol lipid signaling
Q34467697Nuclear lipid signaling
Q74801555Nuclear lipid signaling
Q35120151Nuclear lipid signalling
Q37931279Nuclear phosphoinositides and their roles in cell biology and disease
Q34244229Nuclear phospholipase C and signaling
Q36844777Nuclear phospholipid signaling: phosphatidylinositol-specific phospholipase C and phosphoinositide 3-kinase
Q40439033Nuclear translocation of phospholipase C-delta1 is linked to the cell cycle and nuclear phosphatidylinositol 4,5-bisphosphate.
Q27012953Phosphoinositides: tiny lipids with giant impact on cell regulation
Q28565916Phospholipase Cdelta1 associates with importin beta1 and translocates into the nucleus in a Ca2+-dependent manner
Q44997392Presence of different phospholipase C isoforms in the nucleus and their activation during compensatory liver growth
Q42824508Regulated nucleocytoplasmic transport of protein kinase D in response to G protein-coupled receptor activation
Q74477385Regulation of the intracellular localization of phosphoinositide-specific phospholipase Cdelta(1)
Q57371944The Effector Domain of Myristoylated Alanine-rich C Kinase Substrate Binds Strongly to Phosphatidylinositol 4,5-Bisphosphate
Q28261474The phospholipase C isozymes and their regulation
Q30655339Transient nuclear localization of Fyn kinase during development in zebrafish.

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