Crm1-mediated nuclear export of the Schizosaccharomyces pombe transcription factor Cuf1 during a shift from low to high copper concentrations

scientific article published on 23 March 2007

Crm1-mediated nuclear export of the Schizosaccharomyces pombe transcription factor Cuf1 during a shift from low to high copper concentrations is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/EC.00002-07
P932PMC publication ID1899832
P698PubMed publication ID17384198
P5875ResearchGate publication ID6423731

P2093author name stringSimon Labbé
Jude Beaudoin
P2860cites workMechanisms of Receptor-Mediated Nuclear Import and Nuclear ExportQ22065647
RanBP3 influences interactions between CRM1 and its nuclear protein export substratesQ24522587
Ran-binding protein 3 is a cofactor for Crm1-mediated nuclear protein exportQ24685628
Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved regionQ24685870
CRM1 is an export receptor for leucine-rich nuclear export signalsQ27860453
Site-directed mutagenesis by overlap extension using the polymerase chain reactionQ27860503
Mammalian Ras interacts directly with the serine/threonine kinase RafQ27860833
Yrb2p is a nuclear protein that interacts with Prp20p, a yeast Rcc1 homologueQ27929950
Subcellular localization of Aft1 transcription factor responds to iron status in Saccharomyces cerevisiaeQ27931033
AFT1: a mediator of iron regulated transcriptional control in Saccharomyces cerevisiaeQ27934615
A member of the Ran-binding protein family, Yrb2p, is involved in nuclear protein exportQ27934656
Iron-regulated DNA binding by the AFT1 protein controls the iron regulon in yeast.Q27936505
Exportin 1 (Crm1p) is an essential nuclear export factorQ27939696
Nucleo-cytoplasmic trafficking of metal-regulatory transcription factor 1 is regulated by diverse stress signalsQ28212923
Leptomycin B targets a regulatory cascade of crm1, a fission yeast nuclear protein, involved in control of higher order chromosome structure and gene expressionQ28250231
Metals, toxicity and oxidative stressQ28250561
The transcription factor MTF-1 is essential for basal and heavy metal-induced metallothionein gene expressionQ28369264
Zinc and cadmium can promote rapid nuclear translocation of metal response element-binding transcription factor-1Q28374397
Transcriptional remodeling in response to iron deprivation in Saccharomyces cerevisiaeQ28776183
Identification of a signal for rapid export of proteins from the nucleusQ29547742
CRM1 is responsible for intracellular transport mediated by the nuclear export signalQ29547861
Preparation of high molecular weight RNAQ29614859
Analysis and prediction of leucine-rich nuclear export signalsQ29619228
Regulating access to the genome: nucleocytoplasmic transport throughout the cell cycleQ29619289
Evidence for a role of CRM1 in signal-mediated nuclear protein exportQ29620231
Karyopherins: from nuclear-transport mediators to nuclear-function regulatorsQ30434629
Leucine-rich nuclear-export signals: born to be weakQ31151910
Supraphysiological nuclear export signals bind CRM1 independently of RanGTP and arrest at Nup358.Q33206242
Pipes and wiring: the regulation of copper uptake and distribution in yeast.Q33798087
Classical nuclear localization signals: definition, function, and interaction with importin alphaQ34591163
Molecular mechanisms of copper uptake and distributionQ34662075
Phosphorylation and association with the transcription factor Atf1 regulate localization of Spc1/Sty1 stress-activated kinase in fission yeast.Q35200411
Biologically relevant metal ion-dependent hydroxyl radical generation. An updateQ35230928
Metal-responsive transcription factors that regulate iron, zinc, and copper homeostasis in eukaryotic cells.Q35661293
From aging to virulence: forging connections through the study of copper homeostasis in eukaryotic microorganismsQ35737975
Copper homeostasis in eukaryotes: teetering on a tightropeQ36511427
Identification of a second myosin-II in Schizosaccharomyces pombe: Myp2p is conditionally required for cytokinesisQ36950432
The fission yeast copper-sensing transcription factor Cuf1 regulates the copper transporter gene expression through an Ace1/Amt1-like recognition sequenceQ38302567
Cloned transcription factor MTF-1 activates the mouse metallothionein I promoter.Q38320340
Aft1p and Aft2p mediate iron-responsive gene expression in yeast through related promoter elementsQ38354481
Ctr6, a vacuolar membrane copper transporter in Schizosaccharomyces pombeQ38362779
Comparison of Schizosaccharomyces pombe expression systemsQ40408096
Regulation of the fission yeast transcription factor Pap1 by oxidative stress: requirement for the nuclear export factor Crm1 (Exportin) and the stress-activated MAP kinase Sty1/Spc1Q40444338
Copper induces cytoplasmic retention of fission yeast transcription factor cuf1.Q41823951
The Schizosaccharomyces pombe Cuf1 is composed of functional modules from two distinct classes of copper metalloregulatory transcription factors.Q44310055
Schizosaccharomyces pombe cells lacking the Ran-binding protein Hba1 show a multidrug resistance phenotype due to constitutive nuclear accumulation of Pap1.Q44535713
Functional dissection of Ctr4 and Ctr5 amino-terminal regions reveals motifs with redundant roles in copper transport.Q46872699
A copper-sensing transcription factor regulates iron uptake genes in Schizosaccharomyces pombe.Q47902129
Disruption of the YRB2 gene retards nuclear protein export, causing a profound mitotic delay, and can be rescued by overexpression of XPO1/CRM1.Q52534059
A Novel Nuclear Export Signal Sensitive to Oxidative Stress in the Fission Yeast Transcription Factor Pap1Q57228780
Identification of a novel high affinity copper transport complex in the fission yeast Schizosaccharomyces pombeQ73684847
P433issue5
P921main subjectSchizosaccharomyces pombeQ2236682
P304page(s)764-775
P577publication date2007-03-23
P1433published inEukaryotic CellQ5408685
P1476titleCrm1-mediated nuclear export of the Schizosaccharomyces pombe transcription factor Cuf1 during a shift from low to high copper concentrations
P478volume6

Reverse relations

cites work (P2860)
Q44374871A proline-tyrosine nuclear localization signal (PY-NLS) is required for the nuclear import of fission yeast PAB2, but not of human PABPN1.
Q58797939A role for the transcription factor Mca1 in activating the meiosis-specific copper transporter Mfc1
Q42582975An antisense RNA-mediated mechanism eliminates a meiosis-specific copper-regulated transcript in mitotic cells
Q37339053Both Php4 function and subcellular localization are regulated by iron via a multistep mechanism involving the glutaredoxin Grx4 and the exportin Crm1.
Q35350804Characterization of the nuclear import mechanism of the CCAAT-regulatory subunit Php4.
Q50196407Copper Acquisition and Utilization in Fungi.
Q38164405Copper transport and regulation in Schizosaccharomyces pombe
Q35960811Cuf2 Is a Transcriptional Co-Regulator that Interacts with Mei4 for Timely Expression of Middle-Phase Meiotic Genes
Q35918245Cuf2 is a novel meiosis-specific regulatory factor of meiosis maturation
Q45941482Expression of CRM1 in human gliomas and its significance in p27 expression and clinical prognosis.
Q34914954SQUAMOSA Promoter Binding Protein-Like7 Is a Central Regulator for Copper Homeostasis in Arabidopsis
Q42723295Simon Labbé's work on iron and copper homeostasis
Q39769123Transcriptional regulation of the copper transporter mfc1 in meiotic cells.

Search more.