scholarly article | Q13442814 |
P50 | author | Hengming Ke | Q61519113 |
P2093 | author name string | Yanping Zhang | |
Yoko Itahana | |||
P2860 | cites work | Synergistic activation of transcription by CBP and p53 | Q24311979 |
Binding and modulation of p53 by p300/CBP coactivators | Q24312018 | ||
Acetylation is indispensable for p53 activation | Q24313477 | ||
p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage | Q24530584 | ||
Four domains of p300 each bind tightly to a sequence spanning both transactivation subdomains of p53 | Q24681065 | ||
Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms | Q27730393 | ||
High-resolution structure of the oligomerization domain of p53 by multidimensional NMR | Q27730817 | ||
Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain | Q27860534 | ||
Surfing the p53 network | Q28032484 | ||
Deacetylation of p53 modulates its effect on cell growth and apoptosis | Q28138967 | ||
p53 Transcriptional activity is mediated through the SRC1-interacting domain of CBP/p300 | Q28215076 | ||
Recruitment of p300/CBP in p53-dependent signal pathways | Q28243213 | ||
Identification of p53 as a sequence-specific DNA-binding protein | Q28282745 | ||
p300/MDM2 complexes participate in MDM2-mediated p53 degradation | Q28288274 | ||
Identification of a signal for rapid export of proteins from the nucleus | Q29547742 | ||
DNA damage activates p53 through a phosphorylation-acetylation cascade | Q29616294 | ||
A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking | Q33890625 | ||
p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2. | Q34585107 | ||
Sequence-specific transcriptional activation is essential for growth suppression by p53. | Q35086763 | ||
Nucleocytoplasmic shuttling of p53 is essential for MDM2-mediated cytoplasmic degradation but not ubiquitination | Q35920894 | ||
Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo | Q36601373 | ||
Multiple lysine mutations in the C-terminal domain of p53 interfere with MDM2-dependent protein degradation and ubiquitination | Q39540284 | ||
C-terminal modifications regulate MDM2 dissociation and nuclear export of p53. | Q40157263 | ||
A p53 amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation | Q40800224 | ||
A bipartite nuclear localization signal is required for p53 nuclear import regulated by a carboxyl-terminal domain | Q40919270 | ||
A previously undescribed mutation within the tetramerisation domain of TP53 in a family with Li-Fraumeni syndrome. | Q41192792 | ||
Acetylation of the p53 DNA-binding domain regulates apoptosis induction | Q43019120 | ||
Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosis | Q45345472 | ||
Binding of p53 to the KIX domain of CREB binding protein. A potential link to human T-cell leukemia virus, type I-associated leukemogenesis | Q45747438 | ||
Mechanistic insights into maintenance of high p53 acetylation by PTEN. | Q46035699 | ||
Ubiquitin-dependent distribution of the transcriptional coactivator p300 in cytoplasmic inclusion bodies | Q46927285 | ||
Li-Fraumeni and related syndromes: correlation between tumor type, family structure, and TP53 genotype | Q47418527 | ||
High levels of cytoplasmic HTLV-1 Tax mutant proteins retain a Tax-NF-kappaB-CBP ternary complex in the cytoplasm. | Q55239504 | ||
Phosphorylation of serine 392 stabilizes the tetramer formation of tumor suppressor protein p53 | Q73581630 | ||
Mechanism of folding and assembly of a small tetrameric protein domain from tumor suppressor p53 | Q74523797 | ||
Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases | Q77456357 | ||
Murine double minute (MDM2) blocks p53-coactivator interaction, a new mechanism for inhibition of p53-dependent gene expression | Q77726350 | ||
Tandem dimerization of the human p53 tetramerization domain stabilizes a primary dimer intermediate and dramatically enhances its oligomeric stability | Q79368912 | ||
P433 | issue | 8 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 5158-5164 | |
P577 | publication date | 2008-12-23 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | p53 Oligomerization is essential for its C-terminal lysine acetylation | |
P478 | volume | 284 |
Q41596857 | A new era of studying p53-mediated transcription activation |
Q61798584 | A new technique for predicting intrinsically disordered regions based on average distance map constructed with inter-residue average distance statistics |
Q35050674 | An acetyl-methyl switch drives a conformational change in p53. |
Q51524331 | Analysis of Protein Oligomerization by Electrophoresis. |
Q36486911 | Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress |
Q34452519 | Cancer-associated p53 tetramerization domain mutants: quantitative analysis reveals a low threshold for tumor suppressor inactivation |
Q28510522 | Deacetylation of p53 induces autophagy by suppressing Bmf expression |
Q37636699 | Delphinidin induces apoptosis via cleaved HDAC3-mediated p53 acetylation and oligomerization in prostate cancer cells |
Q37697035 | Evaluation of potential interactions between the metastasis-associated protein S100A4 and the tumor suppressor protein p53. |
Q37428803 | Extensive post-translational modification of active and inactivated forms of endogenous p53. |
Q38250144 | Further evidence for pathogenicity of the TP53 tetramerization domain mutation p.Arg342Pro in Li-Fraumeni syndrome |
Q34968621 | Fuse binding protein antagonizes the transcription activity of tumor suppressor protein p53. |
Q36207381 | Genomic profiling of multiple sequentially acquired tumor metastatic sites from an "exceptional responder" lung adenocarcinoma patient reveals extensive genomic heterogeneity and novel somatic variants driving treatment response |
Q33543092 | Hypoxia inactivates the VHL tumor suppressor through PIASy-mediated SUMO modification |
Q38769335 | Lysines in the tetramerization domain of p53 selectively modulate G1 arrest |
Q45302322 | Modifications of p53 and the DNA damage response in cells expressing mutant form of the protein huntingtin |
Q91626701 | Mutant and Wild-Type Tumor Suppressor p53 Induces p300 Autoacetylation |
Q41993999 | NEURL4 regulates the transcriptional activity of tumor suppressor protein p53 by modulating its oligomerization. |
Q51636057 | Planck-Benzinger thermal work function: thermodynamic characterization of the carboxy-terminus of p53 peptide fragments. |
Q36075403 | Regulation of p53 oligomerization by Ras superfamily protein RBEL1A |
Q24294804 | S100A4 interacts with p53 in the nucleus and promotes p53 degradation |
Q41768808 | Single-Molecule characterization of oligomerization kinetics and equilibria of the tumor suppressor p53 |
Q27657730 | Structural evolution of p53, p63, and p73: Implication for heterotetramer formation |
Q35967111 | Surf the post-translational modification network of p53 regulation |
Q39005319 | The E3 ubiquitin protein ligase HERC2 modulates the activity of tumor protein p53 by regulating its oligomerization |
Q42322261 | The HERC2 ubiquitin ligase is essential for embryonic development and regulates motor coordination. |
Q40649350 | The Protein Acetyltransferase PatZ from Escherichia coli Is Regulated by Autoacetylation-induced Oligomerization |
Q37596345 | The nucleolar protein Myb-binding protein 1A (MYBBP1A) enhances p53 tetramerization and acetylation in response to nucleolar disruption |
Q39495822 | The pathogenic Escherichia coli type III secreted protease NleC degrades the host acetyltransferase p300. |
Q47742599 | Therapeutic targeting of p53: all mutants are equal, but some mutants are more equal than others |
Q38804776 | Tris-acetate polyacrylamide gradient gel electrophoresis for the analysis of protein oligomerization. |
Q37318326 | Ultraslow oligomerization equilibria of p53 and its implications |
Q52651294 | Wild-type and cancer-related p53 proteins are preferentially degraded by MDM2 as dimers rather than tetramers. |
Q34384524 | p53 Dimers associate with a head-to-tail response element to repress cyclin B transcription |
Q28079390 | p53 Proteoforms and Intrinsic Disorder: An Illustration of the Protein Structure-Function Continuum Concept |
Q38740246 | p53 oligomerization status modulates cell fate decisions between growth, arrest and apoptosis. |
Q36567469 | p53 sumoylation: mechanistic insights from reconstitution studies |
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