S100A4 interacts with p53 in the nucleus and promotes p53 degradation

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S100A4 interacts with p53 in the nucleus and promotes p53 degradation is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1021777271
P356DOI10.1038/ONC.2013.213
P3181OpenCitations bibliographic resource ID1333214
P698PubMed publication ID23752197

P50authorBoris ZhivotovskyQ30158891
Janne LehtiöQ37384646
Elena PanizzaQ41561985
P2093author name stringE Vernet
L M Orre
T Gräslund
V O Kaminskyy
P2860cites workCharacterizing proteins and their interactions in cells and tissues using the in situ proximity ligation assayQ24312603
Acetylation is indispensable for p53 activationQ24313477
S100 proteins interact with the N-terminal domain of MDM2Q24336983
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2Q27642888
RING domain E3 ubiquitin ligasesQ27860546
Tumor suppressor p53 protein is a new target for the metastasis-associated Mts1/S100A4 protein: functional consequences of their interactionQ28208109
Binding to intracellular targets of the metastasis-inducing protein, S100A4 (p9Ka)Q28214677
DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2Q28254119
Divorcing ARF and p53: an unsettled caseQ28258356
p53 ubiquitination: Mdm2 and beyondQ29619502
Overexpression of S100A4 in pancreatic ductal adenocarcinomas is associated with poor differentiation and DNA hypomethylation.Q30795307
Self-association of calcium-binding protein S100A4 and metastasisQ33569866
Proteins of the S100 family regulate the oligomerization of p53 tumor suppressorQ33935212
From words to literature in structural proteomicsQ35084576
Overexpression of S100A4 is closely associated with progression of colorectal cancerQ35435739
Calcium-dependent and -independent interactions of the S100 protein family.Q36472950
Expression of S100A4, E-cadherin, alpha- and beta-catenin in breast cancer biopsiesQ36692461
Evaluation of potential interactions between the metastasis-associated protein S100A4 and the tumor suppressor protein p53.Q37697035
Tumor expression of S100A6 correlates with survival of patients with stage I non-small-cell lung cancerQ38289312
Differential expression of S100A2 and S100A4 in lung adenocarcinomas: clinicopathological significance, relationship to p53 and identification of their target genesQ38317520
Expression of S100A2 and S100A4 predicts for disease progression and patient survival in bladder cancerQ38430923
Prognostic significance of calcium-binding protein S100A4 in colorectal cancerQ38454622
Suppression of basal autophagy reduces lung cancer cell proliferation and enhances caspase-dependent and -independent apoptosis by stimulating ROS formationQ39353049
Coexpression and nuclear colocalization of metastasis-promoting protein S100A4 and p53 without mutual regulation in colorectal carcinomaQ39733928
Oligomerization conditions Mdm2-mediated efficient p53 polyubiquitylation but not its proteasomal degradationQ39751187
p53 Oligomerization is essential for its C-terminal lysine acetylationQ39902123
Up-regulation, modification, and translocation of S100A6 induced by exposure to ionizing radiation revealed by proteomics profilingQ40085596
Hypomethylation-induced expression of S100A4 in endometrial carcinomaQ40098520
Identification of protein-protein interactions using in vivo cross-linking and mass spectrometryQ40493018
Modulation of the oligomerization state of p53 by differential binding of proteins of the S100 family to p53 monomers and tetramersQ42285471
The C terminus of p53 binds the N-terminal domain of MDM2.Q42532759
S100A4 (Mts1) gene overexpression is associated with invasion and metastasis of papillary thyroid carcinomaQ43200588
Molecular basis of S100 proteins interacting with the p53 homologs p63 and p73.Q43768901
Expression of S100A4 and Met: potential predictors for metastasis and survival in early-stage breast cancer.Q45254364
Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53.Q45345467
Overexpression of S100A4 is closely related to the aggressiveness of gastric cancerQ47728151
The S100A4 Metastasis Factor Regulates Cellular Motility via a Direct Interaction with Myosin-IIAQ56531468
Metastasis-associated protein Mts1 (S100A4) inhibits CK2-mediated phosphorylation and self-assembly of the heavy chain of nonmuscle myosinQ63362549
Expression of S100A4 protein is associated with metastasis and reduced survival in human bladder cancerQ63966034
Effect of mts1 (S100A4) expression on the progression of human breast cancer cellsQ71574517
Comparison of the metastasis-inducing protein S100A4 (p9ka) with other prognostic markers in human breast cancerQ73645121
Nuclear localization of the metastasis-related protein S100A4 correlates with tumour stage in colorectal cancerQ73750117
Differential expression of S100A2 and S100A4 during progression of human prostate adenocarcinomaQ78729048
Metastasis-associated protein S100A4--a potential prognostic marker for colorectal cancerQ83155625
Posttranslational modifications affect the interaction of S100 proteins with tumor suppressor p53Q84696189
P433issue49
P407language of work or nameEnglishQ1860
P304page(s)5531-40
P577publication date2013-12-05
P1433published inOncogeneQ1568657
P1476titleS100A4 interacts with p53 in the nucleus and promotes p53 degradation
P478volume32

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cites work (P2860)
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Q41661771Calcium-binding protein S100A4 confers mesenchymal progenitor cell fibrogenicity in idiopathic pulmonary fibrosis
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Q58614815Circulating S100 proteins effectively discriminate SLE patients from healthy controls: a cross-sectional study
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Q38734526Knockdown of S100A4 blocks growth and metastasis of anaplastic thyroid cancer cells in vitro and in vivo
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