| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1021197931 |
| P356 | DOI | 10.1038/NRC1954 |
| P3181 | OpenCitations bibliographic resource ID | 2846441 |
| P698 | PubMed publication ID | 16915296 |
| P5875 | ResearchGate publication ID | 6873124 |
| P2093 | author name string | Charles J Sherr | |
| P2860 | cites work | Nucleolar protein B23 has molecular chaperone activities | Q22009438 |
| Identification of a cryptic nucleolar-localization signal in MDM2 | Q22253304 | ||
| The human tumor suppressor arf interacts with spinophilin/neurabin II, a type 1 protein-phosphatase-binding protein | Q24291005 | ||
| A novel putative collaborator of p19ARF | Q24294573 | ||
| Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis | Q24300313 | ||
| CARF is a novel protein that cooperates with mouse p19ARF (human p14ARF) in activating p53 | Q24303502 | ||
| ARF-BP1/Mule is a critical mediator of the ARF tumor suppressor | Q24306428 | ||
| Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis | Q24306444 | ||
| ARF Promotes MDM2 Degradation and Stabilizes p53: ARF-INK4a Locus Deletion Impairs Both the Rb and p53 Tumor Suppression Pathways | Q24321528 | ||
| A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4 | Q24322196 | ||
| Nucleophosmin is essential for ribosomal protein L5 nuclear export | Q24322766 | ||
| A novel ARF-binding protein (LZAP) alters ARF regulation of HDM2 | Q24328749 | ||
| Alternative reading frame protein (ARF)-independent function of CARF (collaborator of ARF) involves its interactions with p53: evidence for a novel p53-activation pathway and its negative feedback control | Q24338110 | ||
| MYC recruits the TIP60 histone acetyltransferase complex to chromatin | Q24535721 | ||
| Targeting of C-terminal binding protein (CtBP) by ARF results in p53-independent apoptosis | Q24548025 | ||
| Evidence of p53-dependent cross-talk between ribosome biogenesis and the cell cycle: effects of nucleolar protein Bop1 on G(1)/S transition | Q24550946 | ||
| Repression of RNA polymerase I transcription by the tumor suppressor p53 | Q24552501 | ||
| N-terminal polyubiquitination and degradation of the Arf tumor suppressor | Q24561681 | ||
| p53-independent functions of the p19(ARF) tumor suppressor | Q24600863 | ||
| Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor | Q24624817 | ||
| Physical and functional interactions of the Arf tumor suppressor protein with nucleophosmin/B23 | Q24629309 | ||
| P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2 | Q24650492 | ||
| Histone sumoylation is associated with transcriptional repression | Q24656259 | ||
| p19Arf suppresses growth, progression, and metastasis of Hras-driven carcinomas through p53-dependent and -independent pathways | Q24799059 | ||
| Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype | Q27824827 | ||
| p14 Arf promotes small ubiquitin-like modifier conjugation of Werners helicase | Q28115495 | ||
| Pex19p dampens the p19ARF-p53-p21WAF1 tumor suppressor pathway | Q28205682 | ||
| Tumor suppression by Ink4a-Arf: progress and puzzles | Q28207959 | ||
| Oligomerization of the human ARF tumor suppressor and its response to oxidative stress | Q28208861 | ||
| Association of p14ARF with the p120E4F transcriptional repressor enhances cell cycle inhibition | Q28215807 | ||
| A short mitochondrial form of p19ARF induces autophagy and caspase-independent cell death | Q28241422 | ||
| DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2 | Q28254119 | ||
| The Ink4a Tumor Suppressor Gene Product, p19Arf, Interacts with MDM2 and Neutralizes MDM2's Inhibition of p53 | Q28266637 | ||
| Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest | Q28270478 | ||
| A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM | Q28270543 | ||
| The ubiquitin ligase HectH9 regulates transcriptional activation by Myc and is essential for tumor cell proliferation | Q28280330 | ||
| Identification of novel ARF binding proteins by two-hybrid screening | Q28305006 | ||
| ARF impedes NPM/B23 shuttling in an Mdm2-sensitive tumor suppressor pathway | Q28506702 | ||
| The ARF tumor suppressor inhibits BCL6-mediated transcriptional repression | Q28509972 | ||
| Role of nucleophosmin in embryonic development and tumorigenesis | Q28591282 | ||
| Nucleophosmin is required for DNA integrity and p19Arf protein stability | Q28593126 | ||
| Protein modification by SUMO | Q29547919 | ||
| Nucleolar Arf tumor suppressor inhibits ribosomal RNA processing | Q40666241 | ||
| P14ARF promotes accumulation of SUMO-1 conjugated (H)Mdm2. | Q40701686 | ||
| p53-independent apoptosis is induced by the p19ARF tumor suppressor | Q40720509 | ||
| Nucleophosmin (B23) targets ARF to nucleoli and inhibits its function | Q41036948 | ||
| p53 represses ribosomal gene transcription | Q42468055 | ||
| Delocalization and destabilization of the Arf tumor suppressor by the leukemia-associated NPM mutant | Q42804288 | ||
| Myeloid leukemia-associated nucleophosmin mutants perturb p53-dependent and independent activities of the Arf tumor suppressor protein | Q42809562 | ||
| Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress | Q42811705 | ||
| Human ARF binds E2F1 and inhibits its transcriptional activity. | Q43583428 | ||
| Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus. | Q43594592 | ||
| MDM2-ARF complex regulates p53 sumoylation | Q44549004 | ||
| The p14ARF tumor suppressor protein facilitates nucleolar sequestration of hypoxia-inducible factor-1alpha (HIF-1alpha ) and inhibits HIF-1-mediated transcription | Q46504176 | ||
| ARF the integrator: linking NF-kappaB, p53 and checkpoint kinases | Q46560525 | ||
| Human Arf tumor suppressor specifically interacts with chromatin containing the promoter of rRNA genes. | Q51595537 | ||
| Localization of phosphorylated forms of Bcl-2 in mitosis: co-localization with Ki-67 and nucleolin in nuclear structures and on mitotic chromosomes | Q53677366 | ||
| p53- and Mdm2-Independent Repression of NF-κB Transactivation by the ARF Tumor Suppressor | Q58287158 | ||
| p16INK4A and p19ARF act in overlapping pathways in cellular immortalization | Q60584728 | ||
| Mapping the functional domains of nucleolar protein B23 | Q73829236 | ||
| P19ARF inhibits the functions of the HPV16 E7 oncoprotein | Q73839521 | ||
| c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability | Q74243929 | ||
| Cooperativity of p19ARF, Mdm2, and p53 in murine tumorigenesis | Q79227607 | ||
| Antagonism of Myc functions by Arf | Q80871514 | ||
| E2F transcriptional repressor complexes are critical downstream targets of p19(ARF)/p53-induced proliferative arrest | Q39404546 | ||
| Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex. | Q39451903 | ||
| Distinct E2F-mediated transcriptional program regulates p14ARF gene expression | Q39491071 | ||
| Differential regulation of E2F1, DP1, and the E2F1/DP1 complex by ARF. | Q39695864 | ||
| Inhibition of p63 transcriptional activity by p14ARF: functional and physical link between human ARF tumor suppressor and a member of the p53 family | Q39998887 | ||
| Regulation of p14ARF through subnuclear compartmentalization | Q40289671 | ||
| p14ARF promotes RB accumulation through inhibition of its Tip60-dependent acetylation | Q40311439 | ||
| p14ARF directly interacts with Myc through the Myc BoxII domain | Q40330377 | ||
| DNA damage disrupts the p14ARF-B23(nucleophosmin) interaction and triggers a transient subnuclear redistribution of p14ARF. | Q40355325 | ||
| ARF and ATM/ATR cooperate in p53-mediated apoptosis upon oncogenic stress. | Q40400130 | ||
| Regulation of NF-kappaB and p53 through activation of ATR and Chk1 by the ARF tumour suppressor | Q40445496 | ||
| p19ARF directly and differentially controls the functions of c-Myc independently of p53. | Q40516548 | ||
| Stability of nucleolar versus non-nucleolar forms of human p14(ARF). | Q40529860 | ||
| ATM activity contributes to the tumor-suppressing functions of p14ARF. | Q40534361 | ||
| Yin Yang 1 is a negative regulator of p53. | Q40542917 | ||
| Myc-ARF (alternate reading frame) interaction inhibits the functions of Myc. | Q40544963 | ||
| p14ARF is a component of the p53 response following ionizing irradiation of normal human fibroblasts | Q40545765 | ||
| Repression of the Arf tumor suppressor by E2F3 is required for normal cell cycle kinetics | Q40549645 | ||
| Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation. | Q40613625 | ||
| Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions | Q29614216 | ||
| DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis | Q29614217 | ||
| Protein degradation and protection against misfolded or damaged proteins | Q29618400 | ||
| Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts | Q29618748 | ||
| Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF | Q29619663 | ||
| SUMO--nonclassical ubiquitin | Q29620234 | ||
| Nucleolar Arf sequesters Mdm2 and activates p53 | Q29620244 | ||
| Major nucleolar proteins shuttle between nucleus and cytoplasm | Q29620425 | ||
| A senescence rescue screen identifies BCL6 as an inhibitor of anti-proliferative p19(ARF)-p53 signaling | Q30828170 | ||
| p14ARF induces G2 arrest and apoptosis independently of p53 leading to regression of tumours established in nude mice | Q33186542 | ||
| Sumoylation induced by the Arf tumor suppressor: a p53-independent function | Q33821331 | ||
| The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2. | Q33889383 | ||
| Arf-dependent regulation of Pdgf signaling in perivascular cells in the developing mouse eye. | Q33910944 | ||
| Human ARF protein interacts with topoisomerase I and stimulates its activity | Q33943467 | ||
| The Arf tumor suppressor gene promotes hyaloid vascular regression during mouse eye development | Q34020783 | ||
| ARF directly binds DP1: interaction with DP1 coincides with the G1 arrest function of ARF. | Q34042864 | ||
| Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stresses | Q34275810 | ||
| ATM promotes apoptosis and suppresses tumorigenesis in response to Myc. | Q34298505 | ||
| Absence of p16INK4a and truncation of ARF tumor suppressors in chickens. | Q34467363 | ||
| p14ARF activates a Tip60-dependent and p53-independent ATM/ATR/CHK pathway in response to genotoxic stress | Q34717991 | ||
| DNA damage induces phosphorylation of the amino terminus of p53 | Q35199554 | ||
| p19ARF targets certain E2F species for degradation. | Q35260543 | ||
| Constitutively active DNA damage checkpoint pathways as the driving force for the high frequency of p53 mutations in human cancer | Q35848503 | ||
| E2F target genes: unraveling the biology | Q35884915 | ||
| Hitting their targets: an emerging picture of E2F and cell cycle control | Q35893526 | ||
| Cancer-associated mutations at the INK4a locus cancel cell cycle arrest by p16INK4a but not by the alternative reading frame protein p19ARF. | Q35960464 | ||
| What have animal models taught us about the p53 pathway? | Q36005936 | ||
| New and unexpected: forkhead meets ARF. | Q36015514 | ||
| Autophagy in metazoans: cell survival in the land of plenty | Q36146937 | ||
| Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2 | Q36174385 | ||
| The role of autophagy in cancer development and response to therapy. | Q36251939 | ||
| Unleashing the power of p53: lessons from mice and men. | Q36371033 | ||
| Nucleophosmin and cancer | Q36516405 | ||
| Regulation of the INK4b-ARF-INK4a tumour suppressor locus: all for one or one for all. | Q36572080 | ||
| Efficient IgG-mediated suppression of primary antibody responses in Fcgamma receptor-deficient mice. | Q37178511 | ||
| Functional and physical interaction of the human ARF tumor suppressor with Tat-binding protein-1. | Q38347016 | ||
| P433 | issue | 9 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 663-73 | |
| P577 | publication date | 2006-09-01 | |
| P13046 | publication type of scholarly work | review article | Q7318358 |
| P1433 | published in | Nature Reviews Cancer | Q641657 |
| P1476 | title | Divorcing ARF and p53: an unsettled case | |
| P478 | volume | 6 |
| Q48225584 | A MYC-aurora kinase A protein complex represents an actionable drug target in p53-altered liver cancer |
| Q42321543 | A conformational switch regulates the ubiquitin ligase HUWE1. |
| Q42806442 | A dose-dependent tug of war involving the NPM1 leukaemic mutant, nucleophosmin, and ARF. |
| Q21562478 | A large scale shRNA barcode screen identifies the circadian clock component ARNTL as putative regulator of the p53 tumor suppressor pathway |
| Q24642046 | A non-tumor suppressor role for basal p19ARF in maintaining nucleolar structure and function |
| Q24316305 | A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability |
| Q35108867 | A p53/ARF-dependent anticancer barrier activates senescence and blocks tumorigenesis without impacting apoptosis |
| Q37081986 | A retroviral mutagenesis screen reveals strong cooperation between Bcl11a overexpression and loss of the Nf1 tumor suppressor gene |
| Q37168640 | A role for Numb in p53 stabilization |
| Q36841427 | A role for the cyclin box in the ubiquitin-mediated degradation of cyclin G1. |
| Q51686167 | A short acidic motif in ARF guards against mitochondrial dysfunction and melanoma susceptibility |
| Q34227622 | AKT regulates NPM dependent ARF localization and p53mut stability in tumors |
| Q36714871 | ARF Represses Androgen Receptor Transactivation in Prostate Cancer |
| Q34148155 | ARF and p53 coordinate tumor suppression of an oncogenic IFN-β-STAT1-ISG15 signaling axis. |
| Q28591778 | ARF functions as a melanoma tumor suppressor by inducing p53-independent senescence |
| Q41914293 | ARF induction in response to DNA strand breaks is regulated by PARP1. |
| Q42143482 | ARF inhibits the growth and malignant progression of non-small-cell lung carcinoma. |
| Q39132153 | ARF regulates the stability of p16 protein via REGγ-dependent proteasome degradation. |
| Q40465644 | ARF sees Pdgfrβ through the miR. |
| Q37360067 | ARF stimulates XPC to trigger nucleotide excision repair by regulating the repressor complex of E2F4. |
| Q37410536 | ARF suppresses hepatic vascular neoplasia in a carcinogen-exposed murine model. |
| Q39070125 | ARF triggers senescence in Brca2-deficient cells by altering the spectrum of p53 transcriptional targets |
| Q64965775 | ARF-NRF2: A new checkpoint for oxidative stress responses? |
| Q33978787 | ARF-induced downregulation of Mip130/LIN-9 protein levels mediates a positive feedback that leads to increased expression of p16Ink4a and p19Arf |
| Q42139522 | ARF: a versatile DNA damage response ally at the crossroads of development and tumorigenesis. |
| Q33728950 | ATM-dependent E2F1 accumulation in the nucleolus is an indicator of ribosomal stress in early response to DNA damage. |
| Q37901431 | Aberrant Activation of Cell Cycle Regulators, Centrosome Amplification, and Mitotic Defects |
| Q39579722 | Aberrant ribosome biogenesis activates c-Myc and ASK1 pathways resulting in p53-dependent G1 arrest |
| Q35791309 | Abnormal MDMX degradation in tumor cells due to ARF deficiency |
| Q37101238 | Activated TNF-alpha/NF-kappaB signaling via down-regulation of Fas-associated factor 1 in asbestos-induced mesotheliomas from Arf knockout mice |
| Q39807622 | Activation of p53 by Nutlin-3a, an antagonist of MDM2, induces apoptosis and cellular senescence in adult T-cell leukemia cells |
| Q36432056 | Acute myeloid leukemia requires Hhex to enable PRC2-mediated epigenetic repression of Cdkn2a |
| Q36177185 | Adenoviral protein V promotes a process of viral assembly through nucleophosmin 1. |
| Q37514846 | Altered nucleophosmin transport in acute myeloid leukaemia with mutated NPM1: molecular basis and clinical implications. |
| Q33597685 | Antitumor effect of novel small chemical inhibitors of Snail-p53 binding in K-Ras-mutated cancer cells |
| Q34056449 | Autoactivation of the MDM2 E3 ligase by intramolecular interaction |
| Q39964587 | BH3 activation blocks Hdmx suppression of apoptosis and cooperates with Nutlin to induce cell death |
| Q34183797 | Bidirectional autoregulatory mechanism of metastasis-associated protein 1-alternative reading frame pathway in oncogenesis |
| Q40060463 | Binding to nucleophosmin determines the localization of human and chicken ARF but not its impact on p53. |
| Q39098284 | Biological and clinical consequences of NPM1 mutations in AML. |
| Q34649019 | Biology and management of pancreatic cancer |
| Q37021785 | Blocking of p53-Snail binding, promoted by oncogenic K-Ras, recovers p53 expression and function |
| Q35950537 | Bridged Analogues for p53-Dependent Cancer Therapy Obtained by S-Alkylation |
| Q37188261 | C/EBPbeta represses p53 to promote cell survival downstream of DNA damage independent of oncogenic Ras and p19(Arf). |
| Q39590059 | CKIα ablation highlights a critical role for p53 in invasiveness control |
| Q34544579 | CRY2 and FBXL3 Cooperatively Degrade c-MYC. |
| Q38853201 | Calpain mediates processing of the translation termination factor eRF3 into the IAP-binding isoform p-eRF3. |
| Q58964578 | Cancer: The blind spot of p53 |
| Q33903965 | Classical and Novel Prognostic Markers for Breast Cancer and their Clinical Significance |
| Q27002356 | Clinical utility of anti-p53auto-antibody: Systematic review and focus on colorectal cancer |
| Q35051842 | Clonal heterogeneity of lymphoid malignancies correlates with poor prognosis |
| Q58610296 | Combating pancreatic cancer with PI3K pathway inhibitors in the era of personalised medicine |
| Q39160326 | Combined p19Arf and interferon-beta gene transfer enhances cell death of B16 melanoma in vitro and in vivo |
| Q33414660 | Comparisons of robustness and sensitivity between cancer and normal cells by microarray data |
| Q35700459 | Concurrent loss of the PTEN and RB1 tumor suppressors attenuates RAF dependence in melanomas harboring (V600E)BRAF |
| Q53073145 | Controlling ARF stability: new players added to the team |
| Q42136182 | Cooperation between Rb and Arf in suppressing mouse retinoblastoma. |
| Q36745375 | Coping with stress: multiple ways to activate p53. |
| Q34778229 | Critical Roles of DMP1 in Human Epidermal Growth Factor Receptor 2/neu-Arf-p53 Signaling and Breast Cancer Development |
| Q38961549 | Curcumin homing to the nucleolus: mechanism for initiation of an apoptotic program |
| Q42381521 | Cytokine-dependent imatinib resistance in mouse BCR-ABL+, Arf-null lymphoblastic leukemia |
| Q36898198 | Different Roles of Negative and Positive Components of the Circadian Clock in Oncogene-induced Neoplastic Transformation |
| Q37344073 | Differential Effects on ARF Stability by Normal versus Oncogenic Levels of c-Myc Expression |
| Q34085053 | Differential p53-independent outcomes of p19(Arf) loss in oncogenesis |
| Q54655468 | Differential roles of the pRb and Arf/p53 pathways in murine naevus and melanoma genesis. |
| Q39035475 | Differentially expressed genes and gene networks involved in pig ovarian follicular atresia |
| Q42506553 | Differing tumor-suppressor functions of Arf and p53 in murine basal cell carcinoma initiation and progression |
| Q39294214 | Direct effects of Bmi1 on p53 protein stability inactivates oncoprotein stress responses in embryonal cancer precursor cells at tumor initiation. |
| Q37343700 | Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator. |
| Q36143489 | Dmp1 and tumor suppression |
| Q42246401 | Dmp1 physically interacts with p53 and positively regulates p53's stability, nuclear localization, and function |
| Q33816125 | Downmodulation of tumor suppressor p53 by T cell receptor signaling is critical for antigen-specific CD4(+) T cell responses |
| Q64066198 | Dual Role of the Alternative Reading Frame ARF Protein in Cancer |
| Q35938545 | Dynamic Protein Interaction Networks and New Structural Paradigms in Signaling |
| Q50536447 | Dynamics of Senescent Cell Formation and Retention Revealed by p14ARF Induction in the Epidermis |
| Q44176860 | Dysfunctional diversity of p53 proteins in adult acute myeloid leukemia: projections on diagnostic workup and therapy |
| Q34645436 | Dysregulation of RNA polymerase I transcription during disease. |
| Q47106948 | Dysregulation of YAP by ARF Stimulated with Tea-derived Carbon Nanodots |
| Q24311697 | E2F1 induces p19INK4d, a protein involved in the DNA damage response, following UV irradiation |
| Q39984104 | Elevated levels of oncogenic protein kinase Pim-1 induce the p53 pathway in cultured cells and correlate with increased Mdm2 in mantle cell lymphoma. |
| Q37277222 | Elimination of p19(ARF)-expressing cells enhances pulmonary function in mice. |
| Q37044618 | Emerging roles of DMP1 in lung cancer |
| Q37666015 | Emerging roles of p53 and other tumour-suppressor genes in immune regulation |
| Q37603053 | Escape from p53-mediated tumor surveillance in neuroblastoma: switching off the p14(ARF)-MDM2-p53 axis. |
| Q39149804 | Establishment of an immortal chicken embryo liver-derived cell line |
| Q33979535 | Expression of arf tumor suppressor in spermatogonia facilitates meiotic progression in male germ cells |
| Q37004455 | Expression of p14ARF, MDM2, and MDM4 in human retinoblastoma |
| Q42020365 | Expression of the Arf tumor suppressor gene is controlled by Tgfbeta2 during development |
| Q40522237 | Forget transcription: translation is where the action is. |
| Q37895408 | FoxM1: A Master Regulator of Tumor Metastasis |
| Q42636934 | FoxO transcription factors suppress Myc-driven lymphomagenesis via direct activation of Arf. |
| Q39126232 | Functional interplay between the DNA-damage-response kinase ATM and ARF tumour suppressor protein in human cancer |
| Q35267844 | Generation and characterization of monoclonal antibodies to NIAM: a nuclear interactor of ARF and Mdm2. |
| Q64916519 | Genetic landscape of long noncoding RNA (lncRNAs) in glioblastoma: identification of complex lncRNA regulatory networks and clinically relevant lncRNAs in glioblastoma. |
| Q60184738 | Genome-wide SNP analysis of Tg.AC transgenic mice reveals an oncogenic collaboration between v-Ha-ras and Ink4a, which is absent in p53 deficiency |
| Q33777454 | Genomics of Squamous Cell Lung Cancer |
| Q47171855 | Germline hemizygous deletion of CDKN2A-CDKN2B locus in a patient presenting with Li-Fraumeni syndrome. |
| Q24299628 | Glioma oncoprotein Bcl2L12 inhibits the p53 tumor suppressor |
| Q40216791 | Globule Leukocytes and Other Mast Cells in the Mouse Intestine |
| Q34026136 | Grp1-associated scaffold protein regulates skin homeostasis after ultraviolet irradiation. |
| Q34091002 | Heterochromatin silencing of p53 target genes by a small viral protein |
| Q33961759 | High-level expression of wild-type p53 in melanoma cells is frequently associated with inactivity in p53 reporter gene assays |
| Q28295783 | Histone Chaperone Jun Dimerization Protein 2 (JDP2): Role in Cellular Senescence and Aging |
| Q36826825 | HuR maintains a replicative life span by repressing the ARF tumor suppressor. |
| Q36394792 | Human DMTF1β antagonizes DMTF1α regulation of the p14(ARF) tumor suppressor and promotes cellular proliferation. |
| Q37583458 | Human Kruppel-related 3 (HKR3) is a novel transcription activator of alternate reading frame (ARF) gene |
| Q40135907 | Human p16gamma, a novel transcriptional variant of p16(INK4A), coexpresses with p16(INK4A) in cancer cells and inhibits cell-cycle progression. |
| Q39223249 | Human rpL3 induces G₁/S arrest or apoptosis by modulating p21 (waf1/cip1) levels in a p53-independent manner |
| Q35665702 | Hypergrowth mTORC1 Signals Translationally Activate the ARF Tumor Suppressor Checkpoint |
| Q39329589 | Hypermethylation-mediated silencing of p14(ARF) in fibroblasts from idiopathic pulmonary fibrosis. |
| Q47239822 | Identification of a novel nucleophosmin-interaction motif in the tumor suppressor p14arf. |
| Q37711928 | Identifying regulatory mechanisms underlying tumorigenesis using locus expression signature analysis |
| Q38176221 | Illuminating p53 function in cancer with genetically engineered mouse models |
| Q41187552 | Immunohistochemical evaluation of p53 and Ki67 expression in skin epithelial tumors. |
| Q64259145 | Impaired ribosome biogenesis: mechanisms and relevance to cancer and aging |
| Q41771208 | In the race for protection, ARF comes second |
| Q46397627 | In vitro genetic screen identifies a cooperative role for LPA signaling and c-Myc in cell transformation. |
| Q35762987 | Inactivation of arf-bp1 Induces p53 Activation and Diabetic Phenotypes in Mice |
| Q28250296 | Inhibition of Crm1-p53 interaction and nuclear export of p53 by poly(ADP-ribosyl)ation |
| Q34963324 | Inhibition of p53 DNA Binding Function by the MDM2 Protein Acidic Domain |
| Q42153635 | Ink4‐Arf locus in cancer and aging |
| Q64883630 | Integrating the DNA damage and protein stress responses during cancer development and treatment. |
| Q34990640 | Intracellular CD24 disrupts the ARF-NPM interaction and enables mutational and viral oncogene-mediated p53 inactivation |
| Q37032577 | Intrinsically unstructured domains of Arf and Hdm2 form bimolecular oligomeric structures in vitro and in vivo |
| Q42877383 | Irreversibility of cellular senescence: dual roles of p16INK4a/Rb-pathway in cell cycle control |
| Q37256435 | It's T-ALL about Notch |
| Q38283101 | JNK1 Deficient Insulin-Producing Cells Are Protected against Interleukin-1β-Induced Apoptosis Associated with Abrogated Myc Expression |
| Q37825439 | Jun dimerization protein 2 controls senescence and differentiation via regulating histone modification |
| Q49206184 | LRP6 targeting suppresses gastric tumorigenesis via P14ARF-Mdm2-P53-dependent cellular senescence. |
| Q36688585 | Large-scale mutagenesis in p19(ARF)- and p53-deficient mice identifies cancer genes and their collaborative networks |
| Q37198572 | Living on a break: cellular senescence as a DNA-damage response |
| Q37025145 | Loss of ARF sensitizes transgenic BRAFV600E mice to UV-induced melanoma via suppression of XPC. |
| Q34523445 | Loss of function tp53 mutations do not accelerate the onset of myc-induced T-cell acute lymphoblastic leukaemia in the zebrafish |
| Q30988586 | Loss of p19(Arf) facilitates the angiogenic switch and tumor initiation in a multi-stage cancer model via p53-dependent and independent mechanisms |
| Q51889545 | MDM2 and MDMX in Cancer and Development |
| Q35568951 | MDM2-mediated degradation of p14ARF: a novel mechanism to control ARF levels in cancer cells |
| Q35597530 | MK3 modulation affects BMI1-dependent and independent cell cycle check-points |
| Q40459014 | MKK7 and ARF: new players in the DNA damage response scenery. |
| Q40859822 | MMP7 interacts with ARF in nucleus to potentiate tumor microenvironments for prostate cancer progression in vivo. |
| Q34504863 | MUC1 oncoprotein suppresses activation of the ARF-MDM2-p53 pathway |
| Q34083178 | MYC cofactors: molecular switches controlling diverse biological outcomes |
| Q38016717 | Mdm2 and MdmX partner to regulate p53 |
| Q41287457 | Mdm2 and tumorigenesis: evolving theories and unsolved mysteries |
| Q37268813 | Mdm2 deficiency suppresses MYCN-Driven neuroblastoma tumorigenesis in vivo |
| Q37508606 | Mdm2-mediated ubiquitylation: p53 and beyond. |
| Q34296531 | Mechanism of p53 stabilization by ATM after DNA damage |
| Q39170177 | Mechanisms of p53 restriction in Merkel cell carcinoma cells are independent of the Merkel cell polyoma virus T antigens. |
| Q96950900 | Melanoma stem cell maintenance and chemo-resistance are mediated by CD133 signal to PI3K-dependent pathways |
| Q37182019 | Melanomagenesis: overcoming the barrier of melanocyte senescence |
| Q36140715 | MicroRNA-155 promotes bladder cancer growth by repressing the tumor suppressor DMTF1. |
| Q34545274 | Mimicking p14ARF phosphorylation influences its ability to restrain cell proliferation |
| Q35857575 | Mitochondrial p32 is a critical mediator of ARF-induced apoptosis |
| Q29615657 | Modes of p53 regulation |
| Q28285685 | Modulation of p53 C-Terminal Acetylation by mdm2, p14ARF, and Cytoplasmic SirT2 |
| Q37257213 | Modulation of the E2F1-driven cancer cell fate by the DNA damage response machinery and potential novel E2F1 targets in osteosarcomas |
| Q52801320 | Molecular Biology and Genetic Mechanisms in the Progression of the Malignant Skin Melanoma |
| Q92052628 | Molecular heterogeneity in peripheral T-cell lymphoma, not otherwise specified revealed by comprehensive genetic profiling |
| Q48558978 | Molecular mechanisms associated with breast cancer based on integrated gene expression profiling by bioinformatics analysis |
| Q37393034 | Monitoring the autophagy pathway in cancer |
| Q93221245 | Mutant p53 Sequestration of the MDM2 Acidic Domain Inhibits E3 Ligase Activity |
| Q40922584 | Mutual Regulation of FOXM1, NPM and ARF Proteins |
| Q40067775 | Mutually exclusive inactivation of DMP1 and ARF/p53 in lung cancer |
| Q89777322 | Myeloid leukemia factor 1 stabilizes tumor suppressor C/EBPα to prevent Trib1-driven acute myeloid leukemia |
| Q36636154 | NAT10 regulates p53 activation through acetylating p53 at K120 and ubiquitinating Mdm2. |
| Q42750027 | NIAM's tangled web of growth control |
| Q34509143 | NIAM-deficient mice are predisposed to the development of proliferative lesions including B-cell lymphomas |
| Q36433816 | NMI mediates transcription-independent ARF regulation in response to cellular stresses |
| Q46292577 | NRF2 Is a Major Target of ARF in p53-Independent Tumor Suppression |
| Q39007737 | Near-genomewide RNAi screening for regulators of BRAF(V600E) -induced senescence identifies RASEF, a gene epigenetically silenced in melanoma |
| Q26824409 | Network calisthenics: control of E2F dynamics in cell cycle entry |
| Q34758670 | New insights into p53 activation |
| Q37502784 | Non-A type nucleophosmin 1 gene mutation predicts poor clinical outcome in de novo adult acute myeloid leukemia: differential clinical importance of NPM1 mutation according to subtype |
| Q91671037 | Non-Coding RNAs in Retinoblastoma |
| Q40101908 | Nuclear expression of E2F4 induces cell death via multiple pathways in normal human intestinal epithelial crypt cells but not in colon cancer cells |
| Q39016272 | Nuclear interactor of ARF and Mdm2 regulates multiple pathways to activate p53. |
| Q41373666 | Nuclear matrix metalloproteinases: functions resemble the evolution from the intracellular to the extracellular compartment |
| Q38810432 | Nuclear trafficking of EGFR by Vps34 represses Arf expression to promote lung tumor cell survival |
| Q92932241 | Nucleolar Stress: hallmarks, sensing mechanism and diseases |
| Q24657753 | Nucleolar protein B23/nucleophosmin regulates the vertebrate SUMO pathway through SENP3 and SENP5 proteases |
| Q34183329 | Nucleolar stress with and without p53. |
| Q34417328 | Nucleostemin stabilizes ARF by inhibiting the ubiquitin ligase ULF. |
| Q38259672 | Nucleostemin: New Stabilizer of ARF. |
| Q33758232 | Nullifying the CDKN2AB locus promotes mutant K-ras lung tumorigenesis. |
| Q41675187 | Nutlin-3a Nanodisks Induce p53 Stabilization and Apoptosis in a Subset of Cultured Glioblastoma Cells |
| Q55365177 | OCT4B regulates p53 and p16 pathway genes to prevent apoptosis of breast cancer cells. |
| Q52727234 | On the relationship status for Arf and NPM1 - it's complicated |
| Q46415253 | Oncogene-induced senescence and its evasion in a mouse model of thyroid neoplasia. |
| Q37001380 | Oncogenes and tumour suppressors take on centrosomes |
| Q92999963 | Oncogenic RUNX3: A Link between p53 Deficiency and MYC Dysregulation |
| Q36832891 | Oncogenic c-Myc-induced lymphomagenesis is inhibited non-redundantly by the p19Arf-Mdm2-p53 and RP-Mdm2-p53 pathways |
| Q61447783 | Overexpression of CCDC69 activates p14/MDM2/p53 pathway and confers cisplatin sensitivity |
| Q37109906 | P53, cyclin-dependent kinase and abnormal amplification of centrosomes |
| Q38238609 | PI3K/Akt-mediated regulation of p53 in cancer |
| Q24321834 | PTEN regulation by Akt-EGR1-ARF-PTEN axis |
| Q38763663 | Peptide-based tumor inhibitor encoding mitochondrial p14(ARF) is highly efficacious to diverse tumors. |
| Q47397272 | Perturbation of RNA Polymerase I transcription machinery by ablation of HEATR1 triggers the RPL5/RPL11-MDM2-p53 ribosome biogenesis stress checkpoint pathway in human cells |
| Q24301920 | Phosphorylation of ETS1 by Src family kinases prevents its recognition by the COP1 tumor suppressor |
| Q34329311 | Phylogenetic patterns of emergence of new genes support a model of frequent de novo evolution |
| Q36508707 | Polycomb Group Protein PHF1 Regulates p53-dependent Cell Growth Arrest and Apoptosis |
| Q26823693 | Protein degradation and the stress response |
| Q34218966 | Proteomic Dissection of the von Hippel–Lindau (VHL) Interactome |
| Q37253577 | RABL6A Promotes Oxaliplatin Resistance in Tumor Cells and Is a New Marker of Survival for Resected Pancreatic Ductal Adenocarcinoma Patients. |
| Q34518263 | RABL6A promotes G1-S phase progression and pancreatic neuroendocrine tumor cell proliferation in an Rb1-dependent manner |
| Q35055073 | RABL6A, a novel RAB-like protein, controls centrosome amplification and chromosome instability in primary fibroblasts. |
| Q37602305 | RAS in cellular transformation and senescence |
| Q40144689 | RNA polymerase III transcription is repressed in response to the tumour suppressor ARF. |
| Q46898426 | RPL23 Links Oncogenic RAS Signaling to p53-Mediated Tumor Suppression |
| Q51097612 | RUNX3 and p53: How Two Tumor Suppressors Cooperate Against Oncogenic Ras? |
| Q37219345 | RasV12-mediated down-regulation of CCAAT/enhancer binding protein beta in immortalized fibroblasts requires loss of p19Arf and facilitates bypass of oncogene-induced senescence |
| Q26783710 | Reactivating p53 functions by suppressing its novel inhibitor iASPP: a potential therapeutic opportunity in p53 wild-type tumors |
| Q41960009 | Reactivating the ARF-p53 axis in AML cells by targeting ULF. |
| Q39063991 | Recurrent mutations, including NPM1c, activate a BRD4-dependent core transcriptional program in acute myeloid leukemia |
| Q96348276 | Regulating tumor suppressor genes: post-translational modifications |
| Q35599086 | Regulation of MDM2 E3 Ligase Activity by Phosphorylation after DNA Damage |
| Q34159585 | Regulation of p14ARF expression by miR-24: a potential mechanism compromising the p53 response during retinoblastoma development |
| Q52582577 | Regulatory Network of ARF in Cancer Development |
| Q34071295 | Repression of BIM mediates survival signaling by MYC and AKT in high-risk T-cell acute lymphoblastic leukemia. |
| Q42734642 | Repression of Dmp1 and Arf transcription by anthracyclins: critical roles of the NF-kappaB subunit p65. |
| Q37262994 | Rescue of key features of the p63-null epithelial phenotype by inactivation of Ink4a and Arf. |
| Q37149722 | Residues in the alternative reading frame tumor suppressor that influence its stability and p53-independent activities |
| Q27006998 | Resistance and gain-of-resistance phenotypes in cancers harboring wild-type p53 |
| Q41710165 | Resistance mechanisms to TP53-MDM2 inhibition identified by in vivo piggyBac transposon mutagenesis screen in an Arf-/- mouse model. |
| Q36616998 | Retinal degeneration depends on Bmi1 function and reactivation of cell cycle proteins |
| Q26829490 | Ribosomal proteins as unrevealed caretakers for cellular stress and genomic instability |
| Q37111920 | Role of DMP1 and its future in lung cancer diagnostics |
| Q24339585 | Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma |
| Q24294804 | S100A4 interacts with p53 in the nucleus and promotes p53 degradation |
| Q38850627 | STAT3 regulated ARF expression suppresses prostate cancer metastasis |
| Q39640395 | SUMO E3 ligase activity of TRIM proteins |
| Q37953790 | SUMO routes ribosome maturation. |
| Q35620891 | Selective requirement of H2B N-Terminal tail for p14ARF-induced chromatin silencing |
| Q35181050 | Signal Transduction Involving the Dmp1 Transcription Factor and its Alteration in Human Cancer |
| Q35206381 | Signaling to p53: ribosomal proteins find their way. |
| Q39184995 | Siva1 inhibits p53 function by acting as an ARF E3 ubiquitin ligase. |
| Q35108014 | Small-molecule modulators of methyl-lysine binding for the CBX7 chromodomain |
| Q27682111 | Structural polymorphism in the N-terminal oligomerization domain of NPM1 |
| Q27322960 | Structure of human MDM2 complexed with RPL11 reveals the molecular basis of p53 activation |
| Q27658148 | Structure-based Design of High Affinity Peptides Inhibiting the Interaction of p53 with MDM2 and MDMX |
| Q36510551 | Syk-mediated tyrosine phosphorylation of mule promotes TNF-induced JNK activation and cell death |
| Q33564558 | Systematic genetic dissection of p14ARF-mediated mitochondrial cell death signaling reveals a key role for p21CDKN1 and the BH3-only protein Puma/bbc3. |
| Q35868379 | TRIM28 Is an E3 Ligase for ARF-Mediated NPM1/B23 SUMOylation That Represses Centrosome Amplification |
| Q24317937 | TSPYL5 suppresses p53 levels and function by physical interaction with USP7 |
| Q35795073 | Targeting the p53 signaling pathway in cancer therapy – the promises, challenges and perils |
| Q34285206 | Tgfbeta signaling directly induces Arf promoter remodeling by a mechanism involving Smads 2/3 and p38 MAPK. |
| Q35118952 | The ARF tumor suppressor inhibits tumor cell colonization independent of p53 in a novel mouse model of pancreatic ductal adenocarcinoma metastasis. |
| Q37602005 | The ARF tumor-suppressor controls Drosha translation to prevent Ras-driven transformation |
| Q37787401 | The E2F1/Rb and p53/MDM2 Pathways in DNA Repair and Apoptosis: Understanding the Crosstalk to Develop Novel Strategies for Prostate Cancer Radiotherapy |
| Q100307199 | The E3 ubiquitin-protein ligase MDM2 is a novel interactor of the von Hippel-Lindau tumor suppressor |
| Q33858272 | The ING gene family in the regulation of cell growth and tumorigenesis |
| Q29614210 | The Ink4/Arf locus is a barrier for iPS cell reprogramming |
| Q35572435 | The LRF transcription factor regulates mature B cell development and the germinal center response in mice |
| Q38184520 | The Mdm network and its regulation of p53 activities: a rheostat of cancer risk |
| Q34030117 | The Mdm2-p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressor |
| Q57166264 | The Nucleolus |
| Q36387610 | The Regulation of Multiple p53 Stress Responses is Mediated through MDM2 |
| Q35103161 | The Ribosomal Protein-Mdm2-p53 Pathway and Energy Metabolism: Bridging the Gap between Feast and Famine |
| Q36387600 | The Roles of MDM2 and MDMX Phosphorylation in Stress Signaling to p53. |
| Q24305067 | The autophagic inducer smARF interacts with and is stabilized by the mitochondrial p32 protein |
| Q92918403 | The cancer driver genes IDH1/2, JARID1C/ KDM5C, and UTX/ KDM6A: crosstalk between histone demethylation and hypoxic reprogramming in cancer metabolism |
| Q41874545 | The cellular abundance of the essential transcription termination factor TTF-I regulates ribosome biogenesis and is determined by MDM2 ubiquitinylation |
| Q42631806 | The human ARF tumor suppressor senses blastema activity and suppresses epimorphic tissue regeneration |
| Q38786667 | The importance of p53 pathway genetics in inherited and somatic cancer genomes. |
| Q53332784 | The leukemia-associated cytoplasmic nucleophosmin mutant is an oncogene with paradoxical functions: Arf inactivation and induction of cellular senescence. |
| Q38261521 | The metastasis-associated gene Prl-3 is a p53 target involved in cell-cycle regulation |
| Q35832954 | The miR-193a-3p-regulated ING5 gene activates the DNA damage response pathway and inhibits multi-chemoresistance in bladder cancer. |
| Q38078390 | The molecular biology of WHO Grade II gliomas |
| Q24312057 | The nucleolar SUMO-specific protease SENP3 reverses SUMO modification of nucleophosmin and is required for rRNA processing |
| Q24597470 | The nucleolus under stress |
| Q31114576 | The p14ARF Alternate Reading Frame Protein Enhances DNA Binding of Topoisomerase I by Interacting with the Serine 506-Phosphorylated Core Domain |
| Q24654198 | The polycomb group gene Bmi1 regulates antioxidant defenses in neurons by repressing p53 pro-oxidant activity |
| Q37274779 | The promiscuity of ARF interactions with the proteasome. |
| Q37599707 | The regulation of MDM2 oncogene and its impact on human cancers |
| Q52777531 | The role of p53 in myelodysplastic syndromes and acute myeloid leukemia: molecular aspects and clinical implications. |
| Q38112497 | The role of ubiquitin modification in the regulation of p53 |
| Q36879301 | Therapeutic targets in the ARF tumor suppressor pathway. |
| Q34890013 | Tight regulation of unstructured proteins: from transcript synthesis to protein degradation |
| Q26774954 | To Know How a Gene Works, We Need to Redefine It First but then, More Importantly, to Let the Cell Itself Decide How to Transcribe and Process Its RNAs |
| Q24301836 | Transcription-independent ARF regulation in oncogenic stress-mediated p53 responses |
| Q37850681 | Transcriptional regulation of cellular senescence |
| Q50027000 | Transcriptional-Readthrough RNAs Reflect the Phenomenon of "A Gene Contains Gene(s)" or "Gene(s) within a Gene" in the Human Genome, and Thus Are Not Chimeric RNAs. |
| Q35155473 | Transgenic and Knockout Mice Models to Reveal the Functions of Tumor Suppressor Genes |
| Q30486791 | Transient expression of the Arf tumor suppressor during male germ cell and eye development in Arf-Cre reporter mice |
| Q43130332 | Tumor suppression by p53 in the absence of Atm. |
| Q37412688 | Tumor suppressive functions of p53 |
| Q38026794 | Tumor suppressive pathways in the control of neurogenesis. |
| Q37414369 | Tumor suppressor genes in myeloid differentiation and leukemogenesis |
| Q38882535 | Tumor-suppressive p53 Signaling Empowers Metastatic Inhibitor KLF17-dependent Transcription to Overcome Tumorigenesis in Non-small Cell Lung Cancer |
| Q34347040 | Ubiquitin and ubiquitin-like proteins in the nucleolus: multitasking tools for a ribosome factory. |
| Q24310413 | Ubiquitin ligase ARF-BP1/Mule modulates base excision repair |
| Q37748214 | Using mice to examine p53 functions in cancer, aging, and longevity |
| Q38793339 | Vaccination using melanoma cells treated with p19arf and interferon beta gene transfer in a mouse model: a novel combination for cancer immunotherapy |
| Q54400552 | YB1 binds to and represses the p16 tumor suppressor gene |
| Q40015788 | hAda3 degradation by papillomavirus type 16 E6 correlates with abrogation of the p14ARF-p53 pathway and efficient immortalization of human mammary epithelial cells |
| Q40142210 | hAda3 regulates p14ARF-induced p53 acetylation and senescence |
| Q37359324 | p14 expression differences in ovarian benign, borderline and malignant epithelial tumors |
| Q39623471 | p14(ARF) inhibits the functions of adenovirus E1A oncoprotein. |
| Q34728302 | p14ARF induces apoptosis via an entirely caspase-3-dependent mitochondrial amplification loop. |
| Q39373570 | p14ARF inhibits the growth of lung adenocarcinoma cells harbouring an EGFR L858R mutation by activating a STAT3-dependent pro-apoptotic signalling pathway |
| Q24296296 | p14ARF interacts with N-Myc and inhibits its transcriptional activity |
| Q34364725 | p14ARF post-transcriptional regulation of nuclear cyclin D1 in MCF-7 breast cancer cells: discrimination between a good and bad prognosis? |
| Q34166041 | p14ARF-induced Apoptosis in p53 Protein-deficient Cells Is Mediated by BH3-only Protein-independent Derepression of Bak Protein through Down-regulation of Mcl-1 and Bcl-xL Proteins |
| Q36944185 | p16INK4a expression and absence of activated B-RAF are independent predictors of chemosensitivity in melanoma tumors |
| Q53257577 | p19(ARF) /p14(ARF) controls oncogenic functions of signal transducer and activator of transcription 3 in hepatocellular carcinoma |
| Q38287966 | p19Arf inhibits the invasion of hepatocellular carcinoma cells by binding to C-terminal binding protein |
| Q28085076 | p53 Acetylation: Regulation and Consequences |
| Q38205676 | p53 and ribosome biogenesis stress: the essentials |
| Q39488131 | p53 binds to and is required for the repression of Arf tumor suppressor by HDAC and polycomb |
| Q34432427 | p53 inactivation by MDM2 and MDMX negative feedback loops in testicular germ cell tumors |
| Q48026380 | p53 loss does not permit escape from BrafV600E-induced senescence in a mouse model of lung cancer |
| Q34300569 | p53 post-translational modification: deregulated in tumorigenesis |
| Q46251110 | p53 promotes AKT and SP1-dependent metabolism through the pentose phosphate pathway that inhibits apoptosis in response to Nutlin-3a |
| Q28264892 | p53-Dependent and p53-independent activation of autophagy by ARF |
| Q38247164 | p53-independent effects of Mdm2. |
| Q28611425 | p53-independent roles of MDM2 in NF-κB signaling: implications for cancer therapy, wound healing, and autoimmune diseases |
| Q37248542 | p53: a molecular marker for the detection of cancer. |
| Q88639252 | tp53-dependent and independent signaling underlies the pathogenesis and possible prevention of Acrofacial Dysostosis-Cincinnati type |
Search more.