Jun dimerization protein 2 controls senescence and differentiation via regulating histone modification

scientific article published on 12 December 2010

Jun dimerization protein 2 controls senescence and differentiation via regulating histone modification is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1155/2011/569034
P932PMC publication ID3005813
P698PubMed publication ID21197464
P5875ResearchGate publication ID49720488

P50authorYing-Chu LinQ37840972
Ming-Feng HouQ72856113
P2093author name stringNaoto Yamaguchi
Kazunari K Yokoyama
Deng-Chyang Wu
Eing-Mei Tsai
Shyh-Shin Chiou
Shin-Wei Wang
Chia-Chen Ku
Hitomi Hasegawa
Shigeo Saito
Yu-Chang Huang
P2860cites workCrystal structure of the nucleosome core particle at 2.8 A resolutionQ22122355
ATF-2 has intrinsic histone acetyltransferase activity which is modulated by phosphorylationQ22254129
PUMA induces the rapid apoptosis of colorectal cancer cellsQ24291462
PUMA, a novel proapoptotic gene, is induced by p53Q24291463
Histone chaperones and nucleosome assemblyQ24294563
NIR is a novel INHAT repressor that modulates the transcriptional activity of p53.Q24297694
Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesisQ24304348
IRF2-binding protein-1 is a JDP2 ubiquitin ligase and an inhibitor of ATF2-dependent transcriptionQ24319080
Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53Q24328775
Extension of life-span by introduction of telomerase into normal human cellsQ24336088
A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1AQ24336667
Defective adipocyte differentiation in mice lacking the C/EBPbeta and/or C/EBPdelta geneQ24532889
Differential targeting of the stress mitogen-activated protein kinases to the c-Jun dimerization protein 2Q24534948
JDP2, a repressor of AP-1, recruits a histone deacetylase 3 complex to inhibit the retinoic acid-induced differentiation of F9 cellsQ24537570
Jun dimerization protein 2 functions as a progesterone receptor N-terminal domain coactivatorQ24537624
Obesity and insulin resistanceQ24607078
A 30-kDa alternative translation product of the CCAAT/enhancer binding protein alpha message: transcriptional activator lacking antimitotic activityQ36601870
The mdm-2 gene is induced in response to UV light in a p53-dependent mannerQ36717209
Retinoblastoma protein functions as a molecular switch determining white versus brown adipocyte differentiation.Q37356575
CCAAT/enhancer binding protein gene promoter: binding of nuclear factors during differentiation of 3T3-L1 preadipocytesQ37452845
Escape from p53-mediated tumor surveillance in neuroblastoma: switching off the p14(ARF)-MDM2-p53 axis.Q37603053
Chaperoning histones during DNA replication and repairQ37689255
A SANT motif in the SMRT corepressor interprets the histone code and promotes histone deacetylationQ38353000
Regulation of peroxisome proliferator-activated receptor gamma expression by adipocyte differentiation and determination factor 1/sterol regulatory element binding protein 1: implications for adipocyte differentiation and metabolismQ39446637
The H3-H4 N-terminal tail domains are the primary mediators of transcription factor IIIA access to 5S DNA within a nucleosomeQ39584897
Inhibition of CBP-mediated protein acetylation by the Ets family oncoprotein PU.1.Q39674745
Retinoic acid blocks adipogenesis by inhibiting C/EBPbeta-mediated transcriptionQ40021186
A novel estrogen receptor alpha-associated protein alters receptor-deoxyribonucleic acid interactions and represses receptor-mediated transcriptionQ40525914
The core histone N-terminal tail domains negatively regulate binding of transcription factor IIIA to a nucleosome containing a 5S RNA gene via a novel mechanismQ40729799
The histone chaperone Nap1 promotes nucleosome assembly by eliminating nonnucleosomal histone DNA interactionsQ40889167
E2F and cell proliferation: a world turned upside downQ41000774
Conditional ectopic expression of C/EBP beta in NIH-3T3 cells induces PPAR gamma and stimulates adipogenesisQ41291617
Histone H3 tail positioning and acetylation by the c-Myb but not the v-Myb DNA-binding SANT domainQ41824791
The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence.Q42123048
Multiple roles for acetylation in the interaction of p300 HAT with ATF-2.Q42434119
Peroxisome proliferator activated receptor gamma, CCAAT/enhancer-binding protein alpha, and cell cycle status regulate the commitment to adipocyte differentiationQ42796360
The human proliferating Cell nuclear antigen regulates transcriptional coactivator p300 activity and promotes transcriptional repression.Q42797840
Regulation of histone acetylation and transcription by nuclear protein pp32, a subunit of the INHAT complex.Q42818908
Isolation of an AP-1 repressor by a novel method for detecting protein-protein interactionsQ24646252
A common allele on chromosome 9 associated with coronary heart diseaseQ24647989
Positive and negative regulation of the cardiovascular transcription factor KLF5 by p300 and the oncogenic regulator SET through interaction and acetylation on the DNA-binding domainQ24648562
Jun Dimerization Protein 2 (JDP2), a Member of the AP-1 Family of Transcription Factor, Mediates Osteoclast Differentiation Induced by RANKLQ24673624
Functional genomics identifies a Myb domain-containing protein family required for assembly of CENP-A chromatinQ24683353
CDK inhibitors: positive and negative regulators of G1-phase progressionQ27860983
The role of chromatin during transcriptionQ27860995
Chromatin modifications and their functionQ27861067
WAF1, a potential mediator of p53 tumor suppressionQ27861121
Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoproteinQ28143509
The c-Jun dimerization protein 2 inhibits cell transformation and acts as a tumor suppressor geneQ28185692
Partial oncogenic transformation of chicken embryo fibroblasts by Jun dimerization protein 2, a negative regulator of TRE- and CRE-dependent transcriptionQ28190113
The AP-1 repressor, JDP2, is a bona fide substrate for the c-Jun N-terminal kinaseQ28198705
Identification of mouse Jun dimerization protein 2 as a novel repressor of ATF-2Q28202835
Ataxin-3 is a histone-binding protein with two independent transcriptional corepressor activitiesQ28203752
Sequence specific transcription factor, JDP2 interacts with histone and inhibits p300-mediated histone acetylationQ28204988
AP-1 repressor protein JDP-2: inhibition of UV-mediated apoptosis through p53 down-regulationQ28210595
Identification of oncogenes collaborating with p27Kip1 loss by insertional mutagenesis and high-throughput insertion site analysisQ28216596
Induction of terminal differentiation by the c-Jun dimerization protein JDP2 in C2 myoblasts and rhabdomyosarcoma cellsQ28217317
JDP2 (Jun Dimerization Protein 2)-deficient mouse embryonic fibroblasts are resistant to replicative senescenceQ28235883
KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor geneQ28250929
DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2Q28254119
Divorcing ARF and p53: an unsettled caseQ28258356
14-3-3sigma is a p53-regulated inhibitor of G2/M progressionQ28276061
The role of basic leucine zipper protein-mediated transcription in physiological and pathological myocardial hypertrophyQ28276096
The transcriptional corepressor, PELP1, recruits HDAC2 and masks histones using two separate domainsQ28285366
The ras recruitment system, a novel approach to the study of protein-protein interactionsQ28285841
Suppression of cell-cycle progression by Jun dimerization protein-2 (JDP2) involves downregulation of cyclin-A2Q28292002
JDP2 suppresses adipocyte differentiation by regulating histone acetylationQ28299658
Regulation of histone acetylation and nucleosome assembly by transcription factor JDP2Q28300507
Apoptosis by death factorQ28304002
Tumor suppressor p53 is a direct transcriptional activator of the human bax geneQ28306186
Corepressors selectively control the transcriptional activity of PPARgamma in adipocytesQ28508812
Transcription. Histones face the FACT.Q52610387
Role of the INK4a locus in tumor suppression and cell mortality.Q53455197
p16INK4A is a robust in vivo biomarker of cellular aging in human skin.Q53605130
Cross-regulation of C/EBP alpha and PPAR gamma controls the transcriptional pathway of adipogenesis and insulin sensitivity.Q54102658
HIRA Is Critical for a Nucleosome Assembly Pathway Independent of DNA SynthesisQ57549500
Tumour biology: Policing of oncogene activity by p53Q57562778
Mdm-2 phosphorylation by DNA-dependent protein kinase prevents interaction with p53Q73883815
A novel estrogen receptor alpha-associated protein, template-activating factor Ibeta, inhibits acetylation and transactivationQ78744916
INK4a/ARF: a multifunctional tumor suppressor locusQ36119162
A common variant of the p16(INK4a) genetic region is associated with physical function in older peopleQ36136695
Genome-wide analysis of HDAC functionQ36253947
Nucleosome displacement in transcriptionQ36554288
Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.Q28590239
Enhanced phosphorylation of p53 by ATM in response to DNA damageQ28609838
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetesQ28680760
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variantsQ29547210
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levelsQ29547214
Cancer cell cyclesQ29547756
A common variant on chromosome 9p21 affects the risk of myocardial infarctionQ29614954
Telomere shortening and tumor formation by mouse cells lacking telomerase RNAQ29615386
PPARs and the complex journey to obesityQ29619271
Chromatin modifications by methylation and ubiquitination: implications in the regulation of gene expressionQ29619380
Essential role of mouse telomerase in highly proliferative organsQ29620451
ATM associates with and phosphorylates p53: mapping the region of interactionQ30175960
Functional interaction of the DNA-binding transcription factor Sp1 through its DNA-binding domain with the histone chaperone TAF-I.Q30935645
The histone octamer is invisible when NF-kappaB binds to the nucleosomeQ33205095
Transcriptional regulation of the p53 tumor suppressor geneQ33547809
Mechanisms of cyclin-dependent kinase regulation: structures of Cdks, their cyclin activators, and Cip and INK4 inhibitorsQ33604662
Tumor suppressor p53 can participate in transcriptional induction of the GADD45 promoter in the absence of direct DNA bindingQ33786522
Effects of Wnt signaling on brown adipocyte differentiation and metabolism mediated by PGC-1alphaQ33823104
Participation of the human p53 3'UTR in translational repression and activation following gamma-irradiationQ33887029
Rb function in cell-cycle regulation and apoptosisQ33900128
Transcriptional regulation of adipogenesisQ33932631
Transcriptional control of adipogenesisQ34001507
The Rb/E2F pathway: expanding roles and emerging paradigmsQ34052659
Molecular regulation of adipogenesisQ34059685
Hormonal signaling and transcriptional control of adipocyte differentiation.Q34101098
PU.1 inhibits the erythroid program by binding to GATA-1 on DNA and creating a repressive chromatin structureQ34116913
Epigenetic consequences of nucleosome dynamicsQ34157982
Histone chaperones, a supporting role in the limelightQ34305755
Human THAP7 is a chromatin-associated, histone tail-binding protein that represses transcription via recruitment of HDAC3 and nuclear hormone receptor corepressorQ34370639
Thanatos-associated protein 7 associates with template activating factor-Ibeta and inhibits histone acetylation to repress transcription.Q34455422
Increased p53 activity does not accelerate telomere-driven ageingQ34683069
Epigenetic determination of a cell-specific gene expression program by ATF-2 and the histone variant macroH2A.Q35102175
Minireview: The adipocyte--at the crossroads of energy homeostasis, inflammation, and atherosclerosisQ35204725
ATF2 is required for amino acid-regulated transcription by orchestrating specific histone acetylation.Q35749733
Heterozygous telomerase deficiency in mouse and man: when less is definitely not more.Q35869863
The key to development: interpreting the histone code?Q36083253
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectcell differentiationQ210861
transcription factorQ407384
nucleoproteinQ419245
transport proteinQ2111029
DNA-binding proteinQ2252764
cellular senescenceQ9075999
nuclear proteinQ16860021
P304page(s)569034
P577publication date2010-12-12
P1433published inJournal of Biomedicine and BiotechnologyQ15752146
P1476titleJun dimerization protein 2 controls senescence and differentiation via regulating histone modification
P478volume2011

Reverse relations

cites work (P2860)
Q55347990A genome-wide association study reveals novel genomic regions and positional candidate genes for fat deposition in broiler chickens.
Q36545857Host JDP2 expression in the bone marrow contributes to metastatic spread
Q52331716Inducers of Senescence, Toxic Compounds, and Senolytics: The Multiple Faces of Nrf2-Activating Phytochemicals in Cancer Adjuvant Therapy.
Q64091959JDP2 and ATF3 deficiencies dampen maladaptive cardiac remodeling and preserve cardiac function
Q55044728JDP2 overexpression provokes cardiac dysfunction in mice.
Q28275331The bZIP repressor proteins, c-Jun dimerization protein 2 and activating transcription factor 3, recruit multiple HDAC members to the ATF3 promoter
Q37311447miR-29 promotes murine osteoclastogenesis by regulating osteoclast commitment and migration

Search more.