| scholarly article | Q13442814 |
| P2093 | author name string | F Ratti | |
| A J Capobianco | |||
| R M Demarest | |||
| P2860 | cites work | MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors | Q24290574 |
| Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover | Q24315524 | ||
| TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms | Q24320364 | ||
| Expression of dominant-negative and mutant isoforms of the antileukemic transcription factor Ikaros in infant acute lymphoblastic leukemia | Q24554417 | ||
| The lymphoid transcription factor LyF-1 is encoded by specific, alternatively spliced mRNAs derived from the Ikaros gene | Q24609038 | ||
| Truncated mammalian Notch1 activates CBF1/RBPJk-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2 | Q24650743 | ||
| Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex | Q24675233 | ||
| Structural basis for autoinhibition of Notch | Q27644319 | ||
| CDK inhibitors: positive and negative regulators of G1-phase progression | Q27860983 | ||
| Expression of aberrantly spliced oncogenic ikaros isoforms in childhood acute lymphoblastic leukemia | Q28138910 | ||
| Notch signaling: from the outside in | Q28139768 | ||
| A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE | Q28139998 | ||
| Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment | Q28202932 | ||
| Functional interaction between SEL-10, an F-box protein, and the nuclear form of activated Notch1 receptor | Q28203706 | ||
| The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog | Q28207494 | ||
| Divorcing ARF and p53: an unsettled case | Q28258356 | ||
| Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain | Q28273268 | ||
| Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J kappa/Su(H) | Q28286560 | ||
| Hes1 directly controls cell proliferation through the transcriptional repression of p27Kip1 | Q28508013 | ||
| Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation | Q28510156 | ||
| Requirement for cyclin D3 in lymphocyte development and T cell leukemias | Q28512456 | ||
| The Ikaros gene encodes a family of functionally diverse zinc finger DNA-binding proteins | Q28513108 | ||
| Characterization of a high-molecular-weight Notch complex in the nucleus of Notch(ic)-transformed RKE cells and in a human T-cell leukemia cell line | Q28580975 | ||
| The Ikaros gene is required for the development of all lymphoid lineages | Q28594316 | ||
| Nuclear Access and Action of Notch In Vivo | Q28646384 | ||
| Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia | Q29614269 | ||
| Notch1 functions as a tumor suppressor in mouse skin | Q29614987 | ||
| FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation | Q29616127 | ||
| p53 ubiquitination: Mdm2 and beyond | Q29619502 | ||
| Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation | Q33732463 | ||
| Function of the c-Myc oncogenic transcription factor. | Q33783511 | ||
| High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice | Q58378937 | ||
| Frequent provirus insertional mutagenesis of Notch1 in thymomas of MMTVD/myc transgenic mice suggests a collaboration of c-myc and Notch1 for oncogenesis | Q59285746 | ||
| A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma | Q71806450 | ||
| Down-regulation of p27Kip1 expression is required for development and function of T cells | Q73311856 | ||
| A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1 | Q73958442 | ||
| Suppression of p53 by Notch in lymphomagenesis: implications for initiation and regression | Q81066571 | ||
| Notch activation is an early and critical event during T-Cell leukemogenesis in Ikaros-deficient mice | Q34233443 | ||
| c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma | Q34958884 | ||
| Notch1 contributes to mouse T-cell leukemia by directly inducing the expression of c-myc | Q35131413 | ||
| Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis | Q35208288 | ||
| myc function and regulation | Q35671084 | ||
| Targeting promiscuous signaling pathways in cancer: another Notch in the bedpost | Q35965123 | ||
| FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors | Q36229551 | ||
| The P53 pathway: what questions remain to be explored? | Q36430168 | ||
| Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia | Q36448329 | ||
| The recombination signal sequence-binding protein RBP-2N functions as a transcriptional repressor | Q36652805 | ||
| The multifaceted role of Notch in cancer | Q36687811 | ||
| Large-scale mutagenesis in p19(ARF)- and p53-deficient mice identifies cancer genes and their collaborative networks | Q36688585 | ||
| Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7 | Q36699782 | ||
| Notch and cancer: a double-edged sword | Q36905503 | ||
| Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia | Q37009642 | ||
| Notch and Ikaros: not only converging players in T cell leukemia | Q37011232 | ||
| Molecular pathogenesis of T-cell leukaemia and lymphoma | Q37141761 | ||
| Notch subunit heterodimerization and prevention of ligand-independent proteolytic activation depend, respectively, on a novel domain and the LNR repeats | Q37574133 | ||
| Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia | Q38287709 | ||
| Notch3 and the Notch3-upregulated RNA-binding protein HuD regulate Ikaros alternative splicing | Q38304159 | ||
| Perturbation of Ikaros isoform selection by MLV integration is a cooperative event in Notch(IC)-induced T cell leukemogenesis | Q38352939 | ||
| Ikaros directly represses the notch target gene Hes1 in a leukemia T cell line: implications for CD4 regulation | Q39782908 | ||
| Notch signaling induces SKP2 expression and promotes reduction of p27Kip1 in T-cell acute lymphoblastic leukemia cell lines | Q40121451 | ||
| Leukemia-associated mutations within the NOTCH1 heterodimerization domain fall into at least two distinct mechanistic classes | Q40273258 | ||
| RBP-J kappa repression activity is mediated by a co-repressor and antagonized by the Epstein-Barr virus transcription factor EBNA2. | Q40397055 | ||
| Childhood T-Cell Acute Lymphoblastic Leukemia: The Dana-Farber Cancer Institute Acute Lymphoblastic Leukemia Consortium Experience | Q40559637 | ||
| PTEN Protects p53 from Mdm2 and Sensitizes Cancer Cells to Chemotherapy | Q40765673 | ||
| HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation | Q40767550 | ||
| Notch(ic)-ER chimeras display hormone-dependent transformation, nuclear accumulation, phosphorylation and CBF1 activation. | Q40860023 | ||
| Differential interaction of the cyclin-dependent kinase (Cdk) inhibitor p27Kip1 with cyclin A-Cdk2 and cyclin D2-Cdk4. | Q41084699 | ||
| Mediation of c-Myc-induced apoptosis by p53. | Q41441186 | ||
| Myc and the cell cycle | Q41703353 | ||
| Cyclin E-CDK2 is a regulator of p27Kip1. | Q42800258 | ||
| Specific EGF repeats of Notch mediate interactions with Delta and serrate: Implications for notch as a multifunctional receptor | Q42806879 | ||
| Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL. | Q43167778 | ||
| Interleukin-7 promotes survival and cell cycle progression of T-cell acute lymphoblastic leukemia cells by down-regulating the cyclin-dependent kinase inhibitor p27(kip1). | Q43718546 | ||
| Roles for c-Myc in self-renewal of hematopoietic stem cells | Q44832250 | ||
| Improved outcome for children with acute lymphoblastic leukemia: results of Total Therapy Study XIIIB at St Jude Children's Research Hospital | Q44976795 | ||
| The suppressor of hairless protein participates in notch receptor signaling | Q47072502 | ||
| Defective expression of Notch1 and Notch2 in connection to alterations of c-Myc and Ikaros in gamma-radiation-induced mouse thymic lymphomas. | Q51026886 | ||
| Notch1-induced transformation of RKE-1 cells requires up-regulation of cyclin D1. | Q51805313 | ||
| Tumor surveillance via the ARF–p53 pathway | Q53430438 | ||
| P433 | issue | 38 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 5082-5091 | |
| P577 | publication date | 2008-09-01 | |
| P13046 | publication type of scholarly work | review article | Q7318358 |
| P1433 | published in | Oncogene | Q1568657 |
| P1476 | title | It's T-ALL about Notch | |
| P478 | volume | 27 |
| Q33967429 | 10058-F4, a c-Myc inhibitor, markedly increases valproic acid-induced cell death in Jurkat and CCRF-CEM T-lymphoblastic leukemia cells |
| Q34517022 | A central role for Notch in effector CD8(+) T cell differentiation |
| Q36100460 | Acute DNA damage activates the tumour suppressor p53 to promote radiation-induced lymphoma |
| Q92947561 | Antileukemia Effects of Notch-Mediated Inhibition of Oncogenic PLK1 in B-Cell Acute Lymphoblastic Leukemia |
| Q35102092 | Assembly of a Notch transcriptional activation complex requires multimerization |
| Q37694748 | Autophagy negatively regulates tumor cell proliferation through phosphorylation dependent degradation of the Notch1 intracellular domain |
| Q34755687 | Beyond the 2008 World Health Organization classification: the role of the hematopathology laboratory in the diagnosis and management of acute lymphoblastic leukemia |
| Q33684219 | Biodiversity and Noncanonical Notch Signaling |
| Q38712111 | Bone morphogenetic protein and Notch signalling crosstalk in poor-prognosis, mesenchymal-subtype colorectal cancer. |
| Q59133598 | CD44 Expression Profile Varies According to Maturational Subtypes and Molecular Profiles of Pediatric T-Cell Lymphoblastic Leukemia |
| Q27334529 | Characterization of two distinct lymphoproliferative diseases caused by ectopic expression of the Notch ligand DLL4 on T cells |
| Q33801752 | Cross-talk between miRNA and Notch signaling pathways in tumor development and progression |
| Q84242761 | Crosstalk of Notch with p53 and p63 in cancer growth control |
| Q39344848 | Cytotoxic activity of the novel Akt inhibitor, MK-2206, in T-cell acute lymphoblastic leukemia. |
| Q24632890 | Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia |
| Q34372409 | Dissecting and Circumventing the Requirement for RAM in CSL-Dependent Notch Signaling |
| Q37331742 | Dual inhibition of class IA phosphatidylinositol 3-kinase and mammalian target of rapamycin as a new therapeutic option for T-cell acute lymphoblastic leukemia |
| Q39118029 | Epidermal growth factor regulates NIKS keratinocyte proliferation through Notch signaling |
| Q28542972 | Focused chemical genomics using zebrafish xenotransplantation as a pre-clinical therapeutic platform for T-cell acute lymphoblastic leukemia |
| Q35678548 | Genetic Analysis of T Cell Lymphomas in Carbon Ion-Irradiated Mice Reveals Frequent Interstitial Chromosome Deletions: Implications for Second Cancer Induction in Normal Tissues during Carbon Ion Radiotherapy |
| Q38223490 | Genomic characterization of acute leukemias |
| Q36339232 | Harnessing the PI3K/Akt/mTOR pathway in T-cell acute lymphoblastic leukemia: eliminating activity by targeting at different levels |
| Q35266310 | IFN-γ promotes graft-versus-leukemia effects without directly interacting with leukemia cells in mice after allogeneic hematopoietic cell transplantation |
| Q33921337 | Identification of novel targets of CSL-dependent Notch signaling in hematopoiesis |
| Q37796303 | Ikaros in immune receptor signaling, lymphocyte differentiation, and function. |
| Q37215128 | Ikaros is required to survive positive selection and to maintain clonal diversity during T-cell development in the thymus |
| Q39909801 | Ikaros-1 couples cell cycle arrest of late striatal precursors with neurogenesis of enkephalinergic neurons |
| Q54250476 | Inhibition of TGF-β and NOTCH Signaling by Cutaneous Papillomaviruses |
| Q57493681 | Intestinal epithelial Notch-1 protects from colorectal mucinous adenocarcinoma |
| Q28260776 | Jdp2 downregulates Trp53 transcription to promote leukaemogenesis in the context of Trp53 heterozygosity |
| Q38726303 | Long non-coding RNA HOTAIR regulates proliferation and invasion via activating Notch signalling pathway in retinoblastoma |
| Q37853939 | Mechanisms controlling hematopoietic stem cell functions during normal hematopoiesis and hematological malignancies |
| Q42371637 | Meta-analysis of the clinical characteristics and prognostic relevance of NOTCH1 and FBXW7 mutation in T-cell acute lymphoblastic leukemia. |
| Q37421023 | Mind bomb 1 regulation of cFLIP interactions |
| Q92652729 | Moving Myeloid Leukemia Drug Discovery Into the Third Dimension |
| Q36627008 | Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling |
| Q36892602 | NOTCH1 activation clinically antagonizes the unfavorable effect of PTEN inactivation in BFM-treated children with precursor T-cell acute lymphoblastic leukemia |
| Q47259599 | NOTCH1 and FBXW7 mutations have a favorable impact on early response to treatment, but not on outcome, in children with T-cell acute lymphoblastic leukemia (T-ALL) treated on EORTC trials 58881 and 58951. |
| Q50355542 | Notch Represses Transcription by PRC2 Recruitment to the Ternary Complex |
| Q37991579 | Notch Signaling in Cancer Stem Cells |
| Q37991581 | Notch and the p53 Clan of Transcription Factors |
| Q34707176 | Notch is oncogenic dominant in T-cell acute lymphoblastic leukemia |
| Q51369795 | Notch pathway plays a novel and critical role in regulating responses of T and antigen-presenting cells in aGVHD. |
| Q37692585 | Notch pathway regulates female germ cell meiosis progression and early oogenesis events in fetal mouse. |
| Q38723830 | Notch regulation of gastrointestinal stem cells |
| Q37874571 | Notch signaling in cardiac valve development and disease. |
| Q34982347 | Notch signaling proteins: legitimate targets for cancer therapy |
| Q37867484 | Notch signalling in solid tumours: a little bit of everything but not all the time |
| Q28486035 | Notch1 is a 5-fluorouracil resistant and poor survival marker in human esophagus squamous cell carcinomas |
| Q36874225 | Notch1 signaling is involved in regulating Foxp3 expression in T-ALL. |
| Q90664283 | Phosphorylation-dependent regulation of the NOTCH1 intracellular domain by dual-specificity tyrosine-regulated kinase 2 |
| Q42016255 | Post-transplant lymphoproliferative disorders: role of viral infection, genetic lesions and antigen stimulation in the pathogenesis of the disease |
| Q39653305 | Preclinical testing of the Akt inhibitor triciribine in T-cell acute lymphoblastic leukemia. |
| Q35103926 | Regulator of myeloid differentiation and function: The secret life of Ikaros |
| Q37962378 | Role of the ubiquitin ligase Fbw7 in cancer progression |
| Q37941310 | Selective repression of Notch pathway target gene transcription |
| Q35692037 | Sequential mutations in Notch1, Fbxw7, and Tp53 in radiation-induced mouse thymic lymphomas |
| Q88720779 | Serrate/Notch Signaling Regulates the Size of the Progenitor Cell Pool in Drosophila Imaginal Rings |
| Q37965247 | T-cell acute lymphoblastic leukaemia: recent molecular biology findings |
| Q83269863 | T-cell acute lymphoblastic leukemia |
| Q46836705 | The NOTCH4-HEY1 pathway induces epithelial mesenchymal transition in head and neck squamous cell carcinoma |
| Q91620670 | The effect of co-occurring lesions on leukaemogenesis and drug response in T-ALL and ETP-ALL |
| Q28487539 | The novel ubiquitin ligase complex, SCF(Fbxw4), interacts with the COP9 signalosome in an F-box dependent manner, is mutated, lost and under-expressed in human cancers |
| Q35999467 | The two faces of FBW7 in cancer drug resistance. |
| Q37269941 | Therapeutic Effect of γ-Secretase Inhibition in KrasG12V-Driven Non-Small Cell Lung Carcinoma by Derepression of DUSP1 and Inhibition of ERK |
| Q36225874 | microRNA signature for human pancreatic cancer invasion and metastasis |
| Q37874926 | p53 and Notch signaling in chronic lymphocytic leukemia: clues to identifying novel therapeutic strategies |
| Q36234694 | α-Synuclein induces alterations in adult neurogenesis in Parkinson disease models via p53-mediated repression of Notch1. |
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