| P2093 | author name string | G Paolo Dotto | |
| P2860 | cites work | p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities | Q22003973 |
| | Human ligands of the Notch receptor | Q22009037 |
| | Rel/NF-kappaB can trigger the Notch signaling pathway by inducing the expression of Jagged1, a ligand for Notch receptors | Q22010043 |
| | Behavioral alterations associated with apoptosis and down-regulation of presenilin 1 in the brains of p53-deficient mice | Q22254072 |
| | MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors | Q24290574 |
| | The p53 family member genes are involved in the Notch signal pathway | Q24291822 |
| | The notch regulator MAML1 interacts with p53 and functions as a coactivator | Q24298020 |
| | Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-kappaB and PPARgamma | Q24301127 |
| | Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes | Q24307538 |
| | p53 isoforms can regulate p53 transcriptional activity. | Q24319034 |
| | The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells | Q24319096 |
| | Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint | Q24324057 |
| | Notch signalling is linked to epidermal cell differentiation level in basal cell carcinoma, psoriasis and wound healing | Q24524157 |
| | p300 acts as a transcriptional coactivator for mammalian Notch-1 | Q24548267 |
| | Efficient tumour formation by single human melanoma cells | Q24648938 |
| | CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors | Q24652007 |
| | Cross-talk between the Notch and TGF-beta signaling pathways mediated by interaction of the Notch intracellular domain with Smad3 | Q24672178 |
| | Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex | Q24675233 |
| | Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKalpha kinases | Q24680631 |
| | Papillomaviruses causing cancer: evasion from host-cell control in early events in carcinogenesis | Q28143403 |
| | Regulation of transcription of the human presenilin-1 gene by ets transcription factors and the p53 protooncogene | Q28143662 |
| | Mammalian Numb is a target protein of Mdm2, ubiquitin ligase | Q28184893 |
| | HES and HERP families: multiple effectors of the Notch signaling pathway | Q28205103 |
| | The role of p63 in development and differentiation of the epidermis | Q28241927 |
| | NUMB controls p53 tumour suppressor activity | Q28263413 |
| | miR-203 represses 'stemness' by repressing DeltaNp63 | Q28280357 |
| | Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation | Q28510156 |
| | IRF-7 is the master regulator of type-I interferon-dependent immune responses | Q28511410 |
| | Role of the Notch ligand Delta1 in embryonic and adult mouse epidermis | Q28512409 |
| | p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours | Q28513003 |
| | Stress response gene ATF3 is a target of c-myc in serum-induced cell proliferation | Q28572315 |
| | p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation | Q28585767 |
| | p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development | Q28587664 |
| | p63 is a p53 homologue required for limb and epidermal morphogenesis | Q28588206 |
| | Notch activation induces apoptosis in neural progenitor cells through a p53-dependent pathway | Q28592687 |
| | Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours | Q29547697 |
| | The canonical Notch signaling pathway: unfolding the activation mechanism | Q29547725 |
| | Notch signalling: a simple pathway becomes complex | Q29555851 |
| | Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia | Q29614269 |
| | A global map of p53 transcription-factor binding sites in the human genome | Q29614400 |
| | Notch1 functions as a tumor suppressor in mouse skin | Q29614987 |
| | Network motifs: theory and experimental approaches | Q29615325 |
| | Regulating the p53 pathway: in vitro hypotheses, in vivo veritas | Q29615658 |
| | Virus induction of human IFN beta gene expression requires the assembly of an enhanceosome | Q29616850 |
| | Transcriptional control of human p53-regulated genes | Q29617650 |
| | Notch-1 regulates transcription of the epidermal growth factor receptor through p53. | Q30435514 |
| | From signals to patterns: space, time, and mathematics in developmental biology | Q33346156 |
| | The p53 family in differentiation and tumorigenesis. | Q53336172 |
| | The Biology of Ewing sarcoma. | Q53575285 |
| | Activated Notch1 interacts with p53 to inhibit its phosphorylation and transactivation. | Q53582142 |
| | A subset of p53-deficient embryos exhibit exencephaly | Q72031963 |
| | Wild-type human p53 activates the human epidermal growth factor receptor promoter | Q72351836 |
| | EGF-receptor tyrosine kinase inhibition induces keratinocyte growth arrest and terminal differentiation | Q73959452 |
| | Acute effects of UVB radiation on the proliferation and differentiation of keratinocytes | Q78402946 |
| | C/EBPbeta participates in regulating transcription of the p53 gene in response to mitogen stimulation | Q79631231 |
| | Off the beaten pathway: the complex cross talk between Notch and NF-kappaB | Q80146628 |
| | The vertebrate segmentation clock | Q80355784 |
| | Suppression of p53 by Notch in lymphomagenesis: implications for initiation and regression | Q81066571 |
| | ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a gamma-secretase inhibitor | Q81249003 |
| | p53 regulation orchestrates the TGF-beta response | Q81355939 |
| | Survival signaling by Notch1: mammalian target of rapamycin (mTOR)-dependent inhibition of p53 | Q83228672 |
| | Transcriptional regulation of the presenilin-1 gene: implication in Alzheimer's disease | Q36991946 |
| | Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia | Q37009642 |
| | Identification of p53 regulators by genome-wide functional analysis | Q37073614 |
| | Sic transit gloria: farewell to the epidermal transit amplifying cell? | Q37121024 |
| | EWS-FLI1 suppresses NOTCH-activated p53 in Ewing's sarcoma | Q37135628 |
| | It's T-ALL about Notch | Q37256435 |
| | Notch tumor suppressor function | Q37256446 |
| | Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition | Q37258903 |
| | Oscillations by the p53-Mdm2 feedback loop | Q37265432 |
| | Recent advances in p53 research: an interdisciplinary perspective. | Q37273304 |
| | EGFR signalling as a negative regulator of Notch1 gene transcription and function in proliferating keratinocytes and cancer | Q37355217 |
| | Differential recognition of response elements determines target gene specificity for p53 and p63 | Q38324246 |
| | Synergy and antagonism between Notch and BMP receptor signaling pathways in endothelial cells. | Q39320608 |
| | Transcriptional cross talk between NF-kappaB and p53. | Q39445554 |
| | Notch signaling is necessary for epithelial growth arrest by TGF-beta | Q39733550 |
| | RBP-Jkappa binds to and represses transcription of the p53 tumor suppressor gene | Q39896991 |
| | The role of the PTEN/AKT Pathway in NOTCH1-induced leukemia | Q39991646 |
| | Transcriptional activation of the human epidermal growth factor receptor promoter by human p53. | Q40020159 |
| | Notch1 activation reduces proliferation in the multipotent hematopoietic progenitor cell line FDCP-mix through a p53-dependent pathway but Notch1 effects on myeloid and erythroid differentiation are independent of p53. | Q40042294 |
| | Regulation of DeltaNp63alpha by tumor necrosis factor-alpha in epithelial homeostasis | Q40047420 |
| | Overexpressed active Notch1 induces cell growth arrest of HeLa cervical carcinoma cells | Q40147287 |
| | Notch1 induces cell cycle arrest and apoptosis in human cervical cancer cells: involvement of nuclear factor kappa B inhibition | Q40168062 |
| | A proline repeat domain in the Notch co-activator MAML1 is important for the p300-mediated acetylation of MAML1. | Q40171091 |
| | TAp73 isoforms antagonize Notch signalling in SH-SY5Y neuroblastomas and in primary neurones. | Q40213854 |
| | Growth suppression induced by Notch1 activation involves Wnt-beta-catenin down-regulation in human tongue carcinoma cells | Q40293810 |
| | p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis | Q40329606 |
| | Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation | Q40444094 |
| | p53 regulates thymic Notch1 activation | Q40584271 |
| | Notch1 signaling inhibits growth of human hepatocellular carcinoma through induction of cell cycle arrest and apoptosis. | Q40606801 |
| | p21/CDKN1A mediates negative regulation of transcription by p53. | Q40647697 |
| | Squamous cell carcinomas and increased apoptosis in skin with inhibited Rel/nuclear factor-kappaB signaling | Q42475218 |
| | Benzo[a]pyrene activates the human p53 gene through induction of nuclear factor kappaB activity | Q42480361 |
| | Impaired notch signaling promotes de novo squamous cell carcinoma formation | Q42499149 |
| | p53 homologue, p51/p63, maintains the immaturity of keratinocyte stem cells by inhibiting Notch1 activity | Q42507106 |
| | Defining the transcriptome of accelerated and replicatively senescent keratinocytes reveals links to differentiation, interferon signaling, and Notch related pathways | Q42678966 |
| | Notch activation suppresses fibroblast growth factor-dependent cellular transformation | Q42804897 |
| | Consequences of Notch-mediated induction of Jagged1. | Q42828884 |
| | Regulation of cancer stem cells by p53. | Q43249111 |
| | Nutlin-3 up-regulates the expression of Notch1 in both myeloid and lymphoid leukemic cells, as part of a negative feedback antiapoptotic mechanism | Q43607424 |
| | The Notch pathway in podocytes plays a role in the development of glomerular disease | Q46725170 |
| | Inhibition of presenilin 1 expression is promoted by p53 and p21WAF-1 and results in apoptosis and tumor suppression | Q47852578 |
| | Notch-dependent cell cycle arrest and apoptosis in mouse embryonic fibroblasts lacking Fbxw7. | Q51952187 |
| | Multiple roles of Notch signaling in the regulation of epidermal development. | Q51959619 |
| | MiRNA expression analysis during normal zebrafish development and following inhibition of the Hedgehog and Notch signaling pathways. | Q51982674 |
| | High-frequency developmental abnormalities in p53-deficient mice. | Q52206956 |
| | Mastermind is a putative activator for Notch. | Q52580782 |
| | Restoration of p53 expression in human cancer cell lines upregulates the expression of Notch1: implications for cancer cell fate determination after genotoxic stress | Q35812707 |
| | Notch in mammary gland development and breast cancer | Q35853093 |
| | Notch signaling in the integrated control of keratinocyte growth/differentiation and tumor suppression | Q35853114 |
| | Regulation of Notch1 gene expression by p53 in epithelial cells | Q35856917 |
| | A dynamic model of keratinocyte stem cell renewal and differentiation: role of the p21WAF1/Cip1 and Notch1 signaling pathways | Q35888270 |
| | DeltaNp63 regulates thymic development through enhanced expression of FgfR2 and Jag2. | Q35901203 |
| | Alterations in NF-kappaB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappaB. | Q35913517 |
| | The strength of indecisiveness: oscillatory behavior for better cell fate determination | Q35991071 |
| | Epidermal growth factor receptor biology in head and neck cancer | Q36500973 |
| | The FoxO3a gene is a key negative target of canonical Notch signalling in the keratinocyte UVB response. | Q36632589 |
| | The multifaceted role of Notch in cancer | Q36687811 |
| | Large-scale mutagenesis in p19(ARF)- and p53-deficient mice identifies cancer genes and their collaborative networks | Q36688585 |
| | Control of keratinocyte proliferation and differentiation by p63. | Q36723013 |
| | Crossing paths with Notch in the hyper-network | Q36743025 |
| | Identification of tumor-initiating cells in a p53-null mouse model of breast cancer | Q36762011 |
| | The link between integration and expression of human papillomavirus type 16 genomes and cellular changes in the evolution of cervical intraepithelial neoplastic lesions | Q36861078 |
| | Transcriptional regulation of the p53 tumor suppressor gene | Q33547809 |
| | Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation | Q33732463 |
| | p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation | Q33733341 |
| | p21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation | Q33855418 |
| | Skin cancer and solar UV radiation | Q33859295 |
| | The p53/p63/p73 family of transcription factors: overlapping and distinct functions. | Q33893917 |
| | Stimulation of human epidermal differentiation by delta-notch signalling at the boundaries of stem-cell clusters. | Q33901073 |
| | Induction of cyclin D1 transcription and CDK2 activity by Notch(ic): implication for cell cycle disruption in transformation by Notch(ic). | Q33969345 |
| | Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation | Q34077697 |
| | Activation of Notch1 signaling is required for beta-catenin-mediated human primary melanoma progression | Q34084509 |
| | Structure and function of IRF-7. | Q34114255 |
| | Alterations in Notch signaling in neoplastic lesions of the human cervix | Q34124673 |
| | DeltaNp63alpha and TAp63alpha regulate transcription of genes with distinct biological functions in cancer and development | Q34197318 |
| | Wnt-related molecules and signaling pathway equilibrium in hematopoiesis | Q34286624 |
| | Robustness of cellular functions | Q34348549 |
| | The epidemiology of UV induced skin cancer | Q34421835 |
| | LIN-12/Notch activation leads to microRNA-mediated down-regulation of Vav in C. elegans | Q34441379 |
| | The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene | Q34462232 |
| | Crystal structure of the CSL-Notch-Mastermind ternary complex bound to DNA. | Q34501252 |
| | Overlapping and distinct mechanisms regulating IRF-3 and IRF-7 function | Q34532718 |
| | Mechanisms of cutaneous toxicities to EGFR inhibitors. | Q34567916 |
| | rugose (rg), a Drosophila A kinase anchor protein, is required for retinal pattern formation and interacts genetically with multiple signaling pathways | Q34615312 |
| | Three habits of highly effective signaling pathways: principles of transcriptional control by developmental cell signaling | Q34649230 |
| | A skin microRNA promotes differentiation by repressing 'stemness'. | Q34756894 |
| | Transcriptome-wide noise controls lineage choice in mammalian progenitor cells | Q34780848 |
| | The Delta Np63 alpha phosphoprotein binds the p21 and 14-3-3 sigma promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations | Q34784078 |
| | A role for p53 in terminal epithelial cell differentiation | Q34790871 |
| | Mastermind-like transcriptional co-activators: emerging roles in regulating cross talk among multiple signaling pathways. | Q34817672 |
| | A comprehensive analysis of the CDKN2A gene in childhood acute lymphoblastic leukemia reveals genomic deletion, copy number neutral loss of heterozygosity, and association with specific cytogenetic subgroups. | Q34847034 |
| | c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma | Q34958884 |
| | Activated Notch1 inhibits p53-induced apoptosis and sustains transformation by human papillomavirus type 16 E6 and E7 oncogenes through a PI3K-PKB/Akt-dependent pathway | Q35020680 |
| | p63: Molecular complexity in development and cancer | Q35700466 |
| | p63 and the epithelial stem cell: more than status quo? | Q35705610 |
| | Specific down-modulation of Notch1 signaling in cervical cancer cells is required for sustained HPV-E6/E7 expression and late steps of malignant transformation | Q35787104 |
| P433 | issue | 8 | |
| P304 | page(s) | 587-595 | |
| P577 | publication date | 2009-07-16 | |
| P1433 | published in | Nature Reviews Cancer | Q641657 |
| P1476 | title | Crosstalk of Notch with p53 and p63 in cancer growth control | |
| P478 | volume | 9 | |