Induction of cyclin D1 transcription and CDK2 activity by Notch(ic): implication for cell cycle disruption in transformation by Notch(ic).

scientific article

Induction of cyclin D1 transcription and CDK2 activity by Notch(ic): implication for cell cycle disruption in transformation by Notch(ic). is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MCB.21.17.5925-5934.2001
P932PMC publication ID87311
P698PubMed publication ID11486031

P50authorChiara RonchiniQ43734964
P2093author name stringA J Capobianco
C Ronchini
P2860cites workCIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complexQ22008610
SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC functionQ22253329
TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasmsQ24320364
CDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phaseQ24554436
A histone deacetylase corepressor complex regulates the Notch signal transduction pathwayQ24598533
Truncated mammalian Notch1 activates CBF1/RBPJk-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2Q24650743
Human cyclin E, a nuclear protein essential for the G1-to-S phase transitionQ24652527
Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)Q24685138
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cellsQ27860717
The retinoblastoma protein and cell cycle controlQ27860722
Involvement of Notch1 in the development of mouse mammary tumorsQ28137765
Notch signaling: from the outside inQ28139768
Functional interaction between the mouse notch1 intracellular region and histone acetyltransferases PCAF and GCN5Q28140561
Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathwayQ28237113
Notch-1 signalling requires ligand-induced proteolytic release of intracellular domainQ28273268
Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancerQ28285050
Signalling downstream of activated mammalian NotchQ28289832
Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localizationQ28290083
Nuclear access and action of notch in vivoQ28646384
Cancer cell cyclesQ29547756
Stat3 as an oncogeneQ29614606
D-type cyclin-dependent kinase activity in mammalian cellsQ29614966
G1 phase progression: cycling on cueQ29615162
Induction of S phase by G1 regulatory factorsQ33781902
Transcriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cellsQ33854194
pp60(v-src) induction of cyclin D1 requires collaborative interactions between the extracellular signal-regulated kinase, p38, and Jun kinase pathways. A role for cAMP response element-binding protein and activating transcription factor-2 in pp60(v-Q33854336
Cyclin D1 is required for transformation by activated Neu and is induced through an E2F-dependent signaling pathwayQ33884776
Alterations in Notch signaling in neoplastic lesions of the human cervixQ34124673
Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regionsQ34295503
Function of a human cyclin gene as an oncogeneQ34994859
Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic miceQ35114942
Cyclin D1 induction in breast cancer cells shortens G1 and is sufficient for cells arrested in G1 to complete the cell cycleQ35677993
Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch allelesQ36366728
Cyclin D1 triggers autonomous growth of breast cancer cells by governing cell cycle exitQ36559825
Induction of cell proliferation in quiescent NIH 3T3 cells by oncogenic c-Raf-1.Q36568076
Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2.Q36573355
The link between integration and expression of human papillomavirus type 16 genomes and cellular changes in the evolution of cervical intraepithelial neoplastic lesionsQ36861078
A new common integration region (int-3) for mouse mammary tumor virus on mouse chromosome 17.Q36907176
Growth-regulated expression of D-type cyclin genes in human diploid fibroblastsQ37257805
Signal transduction by activated mNotch: importance of proteolytic processing and its regulation by the extracellular domain.Q37724159
Transcriptional regulation of rat cyclin D1 gene by CpG methylation status in promoter regionQ38320226
A novel DNA-binding protein, HS2NF5, interacts with a functionally important sequence of the human beta-globin locus control regionQ38350604
Neoplastic transformation by Notch requires nuclear localizationQ39453336
Transduction of Notch2 in feline leukemia virus-induced thymic lymphomaQ39876976
Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27KIP1.Q40022664
Growth factor regulation of cyclin D1 mRNA expression through protein synthesis-dependent and -independent mechanismsQ40241821
Adenovirus-E1A proteins transform cells by sequestering regulatory proteinsQ40823566
Notch(ic)-ER chimeras display hormone-dependent transformation, nuclear accumulation, phosphorylation and CBF1 activation.Q40860023
The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblastsQ40967344
Mammalian G1 cyclins and cell cycle progressionQ40983870
Involvement of RBP-J in biological functions of mouse Notch1 and its derivatives.Q41078359
Myc induces cyclin D1 expression in the absence of de novo protein synthesis and links mitogen-stimulated signal transduction to the cell cycle.Q41426806
Functional Analysis of the TAN-1 Gene, a Human Homolog of Drosophila NotchQ41506198
Differential activation of cyclin and cyclin-dependent kinase genes by adenovirus E1A12S cDNA productQ41522896
The role of cyclin E in cell proliferation, development and cancerQ41744187
Inducible regulatory elements in the human cyclin D1 promoterQ42498965
Wnt1 and MEK1 cooperate to promote cyclin D1 accumulation and cellular transformationQ42803654
Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblastsQ42807624
A carboxy-terminal deletion mutant of Notch1 accelerates lymphoid oncogenesis in E2A-PBX1 transgenic miceQ43457473
The neurogenic suppressor of hairless DNA-binding protein mediates the transcriptional activation of the enhancer of split complex genes triggered by Notch signaling.Q47072129
The suppressor of hairless protein participates in notch receptor signalingQ47072502
Expression of an activated Notch4(int-3) oncoprotein disrupts morphogenesis and induces an invasive phenotype in mammary epithelial cells in vitro.Q52539130
Identity of the beta-globin locus control region binding protein HS2NF5 as the mammalian homolog of the notch-regulated transcription factor suppressor of hairless.Q52565531
Overexpression of cyclin D1 in rat fibroblasts causes abnormalities in growth control, cell cycle progression and gene expression.Q53476711
Frequent provirus insertional mutagenesis of Notch1 in thymomas of MMTVD/myc transgenic mice suggests a collaboration of c-myc and Notch1 for oncogenesisQ59285746
Cyclin E-induced S phase without activation of the pRb/E2F pathway.Q60200141
Novel association of a diverse range of genes with renal cell carcinoma as identified by differential displayQ73174253
Acute glucose-induced downregulation of PKC-betaII accelerates cultured VSMC proliferationQ74172709
Ras pathway signals are required for notch-mediated oncogenesisQ74298005
P433issue17
P407language of work or nameEnglishQ1860
P304page(s)5925-5934
P577publication date2001-09-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleInduction of cyclin D1 transcription and CDK2 activity by Notch(ic): implication for cell cycle disruption in transformation by Notch(ic).
P478volume21

Reverse relations

cites work (P2860)
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