Structurally conserved binding motifs of transcriptional regulators to notch nuclear effector CSL

scientific article published on 22 September 2019

Structurally conserved binding motifs of transcriptional regulators to notch nuclear effector CSL is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1177/1535370219877818
P932PMC publication ID6920672
P698PubMed publication ID31544502

P50authorDaniel P. HallQ86320397
P2093author name stringRhett A Kovall
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RITA, a novel modulator of Notch signalling, acts via nuclear export of RBP-J.Q24308025
Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnoverQ24315524
SHARP is a novel component of the Notch/RBP-Jkappa signalling pathwayQ24534941
p300 and PCAF act cooperatively to mediate transcriptional activation from chromatin templates by notch intracellular domains in vitroQ24537773
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Truncated mammalian Notch1 activates CBF1/RBPJk-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2Q24650743
A conserved structural motif reveals the essential transcriptional repression function of Spen proteins and their role in developmental signalingQ24671921
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Conformational Locking upon Cooperative Assembly of Notch Transcription ComplexesQ27677210
Structure and Function of the CSL-KyoT2 Corepressor Complex: A Negative Regulator of Notch SignalingQ27680715
Structural requirements for assembly of the CSL.intracellular Notch1.Mastermind-like 1 transcriptional activation complexQ28184514
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Three-Dimensional Structures of Acidic and Basic Fibroblast Growth FactorsQ28267322
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Direct regulation of Gata3 expression determines the T helper differentiation potential of NotchQ28594879
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Thermodynamic analysis of the CSL x Notch interaction: distribution of binding energy of the Notch RAM region to the CSL beta-trefoil domain and the mode of competition with the viral transactivator EBNA2.Q33673817
Induction of cyclin D1 transcription and CDK2 activity by Notch(ic): implication for cell cycle disruption in transformation by Notch(ic).Q33969345
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Deltex1 redirects lymphoid progenitors to the B cell lineage by antagonizing Notch1.Q34116313
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Epstein-Barr virus nuclear protein 3C binds to the N-terminal (NTD) and beta trefoil domains (BTD) of RBP/CSL; only the NTD interaction is essential for lymphoblastoid cell growthQ35014692
Nrarp is a novel intracellular component of the Notch signaling pathwayQ35080412
Structural and functional analysis of the repressor complex in the Notch signaling pathway of Drosophila melanogasterQ35188610
The Notch signalling system: recent insights into the complexity of a conserved pathwayQ35206852
Quantitative dissection of the Notch:CSL interaction: insights into the Notch-mediated transcriptional switch.Q35749862
Contribution of conserved amino acids in mediating the interaction between EBNA2 and CBF1/RBPJkQ35835726
Characterization of CSL (CBF-1, Su(H), Lag-1) mutants reveals differences in signaling mediated by Notch1 and Notch2.Q36318700
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Mechanism of kappa B DNA binding by Rel/NF-kappa B dimersQ38312000
Kaposi's sarcoma-associated herpesvirus viral interferon regulatory factor 4 (vIRF4/K10) is a novel interaction partner of CSL/CBF1, the major downstream effector of Notch signaling.Q38340693
Mechanical Allostery: Evidence for a Force Requirement in the Proteolytic Activation of NotchQ38866592
Notch signalling in contextQ38923306
The Canonical Notch Signaling Pathway: Structural and Biochemical Insights into Shape, Sugar, and ForceQ39293613
LIM protein KyoT2 negatively regulates transcription by association with the RBP-J DNA-binding proteinQ39631445
Mutational and energetic studies of Notch 1 transcription complexesQ40031628
RBPJ/CBF1 interacts with L3MBTL3/MBT1 to promote repression of Notch signaling via histone demethylase KDM1A/LSD1.Q44461187
Masking of the CBF1/RBPJ kappa transcriptional repression domain by Epstein-Barr virus EBNA2.Q44697821
Notch Signaling in Development, Tissue Homeostasis, and DiseaseQ46795621
Structure-function analysis of RBP-J-interacting and tubulin-associated (RITA) reveals regions critical for repression of Notch target genesQ51012058
Mastermind is a putative activator for Notch.Q52580782
Regulation of marginal zone B cell development by MINT, a suppressor of Notch/RBP-J signaling pathwayQ52603545
Structural and Functional Studies of the RBPJ-SHARP Complex Reveal a Conserved Corepressor Binding SiteQ61445371
CSL-Associated Corepressor and Coactivator ComplexesQ90378819
P433issue17
P304page(s)1520-1529
P577publication date2019-09-22
P1433published inExperimental Biology and MedicineQ15716535
P1476titleStructurally conserved binding motifs of transcriptional regulators to notch nuclear effector CSL
P478volume244

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