| scholarly article | Q13442814 |
| P819 | ADS bibcode | 1991Sci...251...90Z |
| P356 | DOI | 10.1126/SCIENCE.1702556 |
| P953 | full work available at URL | https://syndication.highwire.org/content/doi/10.1126/science.1702556 |
| P3181 | OpenCitations bibliographic resource ID | 4554772 |
| P698 | PubMed publication ID | 1702556 |
| P2093 | author name string | D. C. Rees | |
| X. Zhu | |||
| H. Komiya | |||
| T. Arakawa | |||
| A. Chirino | |||
| B. T. Hsu | |||
| G. M. Fox | |||
| S. Faham | |||
| P2860 | cites work | Israel Medical Association Journal | Q133979 |
| Journal of Applied Crystallography | Q3186893 | ||
| Molecular and Cellular Biology | Q3319478 | ||
| Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth | Q24295049 | ||
| cDNA sequence of human transforming gene hst and identification of the coding sequence required for transforming activity | Q24610620 | ||
| Structure of interleukin 1 alpha at 2.7-A resolution | Q27684125 | ||
| Structure of E. coli glutaminyl-tRNA synthetase complexed with tRNA(Gln) and ATP at 2.8 A resolution | Q27690160 | ||
| Crystal structure of recombinant human interleukin-1 beta at 2.0 A resolution | Q27700151 | ||
| The Protein Data Bank: a computer-based archival file for macromolecular structures | Q27860989 | ||
| Brain-derived acidic fibroblast growth factor: complete amino acid sequence and homologies | Q28236262 | ||
| An oncogene isolated by transfection of Kaposi's sarcoma DNA encodes a growth factor that is a member of the FGF family | Q28285491 | ||
| Resolution of phase ambiguity in macromolecular crystallography | Q29617474 | ||
| Diffraction methods for biological macromolecules. Interactive computer graphics: FRODO | Q29618849 | ||
| Angiogenic factors | Q29620582 | ||
| Receptor- and heparin-binding domains of basic fibroblast growth factor | Q33564620 | ||
| Basic fibroblast growth factor is a substrate for protein phosphorylation and is phosphorylated by capillary endothelial cells in culture. | Q33852910 | ||
| Crystal structure of the complex of porcine trypsin with soybean trypsin inhibitor (Kunitz) at 2.6 Å resolution | Q34210825 | ||
| Structural characterization and biological functions of fibroblast growth factor | Q34396763 | ||
| Primary structure of bovine pituitary basic fibroblast growth factor (FGF) and comparison with the amino-terminal sequence of bovine brain acidic FGF. | Q37534320 | ||
| The heparin-binding (fibroblast) growth factor family of proteins | Q38286731 | ||
| Recovery of mitogenic activity of a growth factor mutant with a nuclear translocation sequence. | Q38339080 | ||
| Crystal structure of the cytokine interleukin-1 beta. | Q41091169 | ||
| Reductive methylation of lysine residues in acidic fibroblast growth factor: effect on mitogenic activity and heparin affinity | Q42805087 | ||
| Thrombin inactivates acidic fibroblast growth factor but not basic fibroblast growth factor | Q48088817 | ||
| Crystallographic refinement by simulated annealing. Application to a 2.8 A resolution structure of aspartate aminotransferase. | Q54740459 | ||
| The detection of sub-units within the crystallographic asymmetric unit | Q56432754 | ||
| Three-fold structural pattern in the soybean trypsin inhibitor (Kunitz) | Q66994216 | ||
| Carboxyl-terminal structure of basic fibroblast growth factor significantly contributes to its affinity for heparin | Q68499278 | ||
| Stereochemically restrained refinement of macromolecular structures | Q69806243 | ||
| P433 | issue | 4989 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 90-3 | |
| P577 | publication date | 1991-01-04 | |
| P1433 | published in | Science | Q192864 |
| P1476 | title | Three-dimensional structures of acidic and basic fibroblast growth factors | |
| Three-Dimensional Structures of Acidic and Basic Fibroblast Growth Factors | |||
| P478 | volume | 251 |
| Q57836479 | 15N NMR Relaxation Studies of Free and Ligand-bound Human Acidic Fibroblast Growth Factor |
| Q54600997 | 1H, 15N, 13C and 13CO assignments and secondary structure determination of basic fibroblast growth factor using 3D heteronuclear NMR spectroscopy. |
| Q36247964 | A 10-amino acid sequence of fibroblast growth factor 2 is sufficient for its mitogenic activity on neural progenitor cells. |
| Q48052636 | A cDNA encoding fish fibroblast growth factor-2, which lacks alternative translation initiation |
| Q33584177 | A heparin mimetic isolated from a marine shrimp suppresses neovascularization. |
| Q24309431 | A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types |
| Q27642593 | Accommodation of a highly symmetric core within a symmetric protein superfold |
| Q42824584 | Acidic fibroblast growth factor accelerates dermal wound healing |
| Q48204044 | Amplification and sequencing of mRNA encoding acidic fibroblast growth factor (aFGF) from porcine heart |
| Q38290536 | An S116R Phosphorylation Site Mutation in Human Fibroblast Growth Factor-1 Differentially Affects Mitogenic and Glucose-Lowering Activities |
| Q47857405 | An emerging case for membrane pore formation as a common mechanism for the unconventional secretion of FGF2 and IL-1β. |
| Q30350474 | An integrated platform for automated analysis of protein NMR structures. |
| Q27759120 | Barley alpha-amylase bound to its endogenous protein inhibitor BASI: crystal structure of the complex at 1.9 A resolution |
| Q59619014 | Basic fibroblast growth factor is cardioprotective in ischemia-reperfusion injury |
| Q34074836 | Biochemical analysis of pathogenic ligand-dependent FGFR2 mutations suggests distinct pathophysiological mechanisms for craniofacial and limb abnormalities |
| Q42140621 | Biochemical characterization of the molecular interaction between recombinant basic fibroblast growth factor and a recombinant soluble fibroblast growth factor receptor |
| Q37261502 | Biological functions of the low and high molecular weight protein isoforms of fibroblast growth factor-2 in cardiovascular development and disease |
| Q33638611 | Cellular aspects of trophic actions in the nervous system. |
| Q30439922 | Cellular signaling by fibroblast growth factors (FGFs) and their receptors (FGFRs) in male reproduction |
| Q41588026 | Characterization of the nuclear translocation of acidic fibroblast growth factor |
| Q42769610 | Cleavage of K-FGF produces a truncated molecule with increased biological activity and receptor binding affinity |
| Q39178586 | Computational drill down on FGF1-heparin interactions through methodological evaluation |
| Q71683982 | Conditioned media of carcinoma cells cultured in hypoxic microenvironment stimulate angiogenesis in vitro; relationship to basic fibroblast growth factor |
| Q36217292 | Conversion of a paracrine fibroblast growth factor into an endocrine fibroblast growth factor |
| Q38320039 | Cooperative dimerization of fibroblast growth factor 1 (FGF1) upon a single heparin saccharide may drive the formation of 2:2:1 FGF1.FGFR2c.heparin ternary complexes |
| Q39900683 | Cooperative heparin-mediated oligomerization of fibroblast growth factor-1 (FGF1) precedes recruitment of FGFR2 to ternary complexes. |
| Q30175835 | Correlation between the 1.6 A crystal structure and mutational analysis of keratinocyte growth factor |
| Q27627811 | Crystal structure of fibroblast growth factor 9 reveals regions implicated in dimerization and autoinhibition |
| Q24290496 | Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin |
| Q27622086 | Crystal structure of the cysteine-rich domain of mannose receptor complexed with a sulfated carbohydrate ligand |
| Q22254157 | Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity |
| Q41917265 | Crystallization and preliminary X-ray analysis of a protease inhibitor from the latex of Carica papaya. |
| Q38331819 | Cyclooxygenase gene expression is down-regulated by heparin-binding (acidic fibroblast) growth factor-1 in human endothelial cells |
| Q43828418 | Cysteine to serine substitutions in basic fibroblast growth factor: effect on inclusion body formation and proteolytic susceptibility during in vitro refolding |
| Q46962010 | Cytotoxic effects of acrylamide in nerve growth factor or fibroblast growth factor 1-induced neurite outgrowth in PC12 cells |
| Q40632639 | Decapeptide with fibroblast growth factor (FGF)‐5 partial sequence inhibits hair growth suppressing activity of FGF‐5 |
| Q37885356 | Delivery approaches for angiogenic growth factors in the treatment of ischemic conditions |
| Q37137867 | Developmental SHP2 dysfunction underlies cardiac hypertrophy in Noonan syndrome with multiple lentigines |
| Q38303388 | Different effects of mucosal, bovine lung and chemically modified heparin on selected biological properties of basic fibroblast growth factor |
| Q38331346 | Diversity does make a difference: fibroblast growth factor-heparin interactions |
| Q37336121 | Dominant-negative kinase domain mutations in FGFR1 can explain the clinical severity of Hartsfield syndrome |
| Q33840872 | Effect of basic fibroblast growth factor and cytochrome c peroxidase combination in transgenic mice corneal epithelial healing process after excimer laser photoablation. |
| Q67705851 | Effect of polyanions on the refolding of human acidic fibroblast growth factor |
| Q33780666 | Effect of the combination of basic fibroblast growth factor and cysteine on corneal epithelial healing after photorefractive keratectomy in patients affected by myopia |
| Q77826797 | Effects of the binding of a dextran derivative on fibroblast growth factor 2: secondary structure and receptor-binding studies |
| Q73407623 | Enhancement of bFGF export associated with malignant progression of human salivary gland cell clones |
| Q53327691 | Expression and analysis of heparin-binding regions of the amyloid precursor protein of Alzheimer's disease. |
| Q42824783 | Expression and purification of biologically active human FGF2 containing the b'a' domains of human PDI in Escherichia coli |
| Q41026342 | FGF2-Heparin co-crystal complex-assisted design of mutants FGF1 and FGF7 with predictable heparin affinities |
| Q34190379 | Factors affecting short-term and long-term stabilities of proteins |
| Q38794405 | Fibroblast Growth Factor 21 As an Emerging Therapeutic Target for Type 2 Diabetes Mellitus |
| Q36012592 | Fibroblast Growth Factor Homologous Factors: New Roles in Neuronal Health and Disease |
| Q24305543 | Fibroblast growth factor (FGF) homologous factors share structural but not functional homology with FGFs |
| Q24320072 | Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development |
| Q24628289 | Fibroblast growth factor homologous factors are intracellular signaling proteins |
| Q24542507 | Fibroblast growth factors |
| Q30650531 | Fibroblast growth factors 1 and 2 are distinct in oligomerization in the presence of heparin-like glycosaminoglycans |
| Q35081473 | Fibroblast growth factors as regulators of central nervous system development and function |
| Q28272364 | Fibroblast growth factors as tissue repair and regeneration therapeutics |
| Q35229559 | Five FGF receptors with distinct expression patterns |
| Q71585615 | Fluorescence resonance energy transfer reveals interleukin (IL)-1-dependent aggregation of IL-1 type I receptors that correlates with receptor activation |
| Q34041339 | Formation of an active dimer during storage of interleukin-1 receptor antagonist in aqueous solution |
| Q42810170 | Formulation design of acidic fibroblast growth factor |
| Q33597455 | Function and biological applications of catalytic nucleic acids |
| Q40427775 | Functions of fibroblast growth factors and their receptors |
| Q40918251 | Functions of fibroblast growth factors in vertebrate development |
| Q47148090 | Gas-Phase Analysis of the Complex of Fibroblast GrowthFactor 1 with Heparan Sulfate: A Traveling Wave Ion Mobility Spectrometry (TWIMS) and Molecular Modeling Study |
| Q46277587 | Glu-96 of basic fibroblast growth factor is essential for high affinity receptor binding. Identification by structure-based site-directed mutagenesis |
| Q34973852 | Growth factors and steroid hormones: a complex interplay in the hypothalamic control of reproductive functions. |
| Q33864454 | Highly sulfated nonreducing end-derived heparan sulfate domains bind fibroblast growth factor-2 with high affinity and are enriched in biologically active fractions |
| Q30168817 | Identification and characterization of an equilibrium intermediate in the unfolding pathway of an all beta-barrel protein. |
| Q22253413 | Identification and initial characterization of four novel members of the interleukin-1 family |
| Q40790538 | Identification of a common hyaluronan binding motif in the hyaluronan binding proteins RHAMM, CD44 and link protein. |
| Q28202842 | Identification of a new fibroblast growth factor receptor, FGFR5 |
| Q39525937 | Identification of polyoxometalates as inhibitors of basic fibroblast growth factor. |
| Q24550863 | Identification of receptor and heparin binding sites in fibroblast growth factor 4 by structure-based mutagenesis |
| Q40860252 | Identification of residues important both for primary receptor binding and specificity in fibroblast growth factor-7. |
| Q41494938 | In vitro inhibition of the actions of basic FGF by a novel 16 amino acid peptide |
| Q42576867 | Increased protein stability of FGF1 can compensate for its reduced affinity for heparin |
| Q27331474 | Inflammasome-dependent IL-1β release depends upon membrane permeabilisation |
| Q51191457 | Inhibition of in-stent restenosis by oral copper chelation in porcine coronary arteries. |
| Q41037216 | Interactions of putative heparin-binding domains of basic fibroblast growth factor and its receptor, FGFR-1, with heparin using synthetic peptides |
| Q24315035 | Interleukin 1 is processed and released during apoptosis |
| Q41326561 | Interleukin-1 beta secretion. A possible multistep process that is regulated in a cell type-specific manner |
| Q35192351 | Isolation and expression in Escherichia coli of hepB and hepC, genes coding for the glycosaminoglycan-degrading enzymes heparinase II and heparinase III, respectively, from Flavobacterium heparinum |
| Q36665313 | Isolation of peptides that inhibit binding of basic fibroblast growth factor to its receptor from a random phage-epitope library |
| Q28278567 | Keratinocyte growth factor/fibroblast growth factor 7, a homeostatic factor with therapeutic potential for epithelial protection and repair |
| Q72191030 | Ligand-specific structural domains in the fibroblast growth factor receptor |
| Q42454319 | Localization of acidic fibroblast growth factor within the mouse brain using biochemical and immunocytochemical techniques |
| Q42814508 | Molecular Level Interaction of the Human Acidic Fibroblast Growth Factor with the Antiangiogenic Agent, Inositol Hexaphosphate, |
| Q36448331 | Molecular characteristics of fibroblast growth factor-fibroblast growth factor receptor-heparin-like glycosaminoglycan complex |
| Q33240624 | Molecular cloning of a human basic fibroblast growth factor receptor cDNA and expression of a biologically active extracellular domain in a baculovirus system |
| Q24683254 | Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members |
| Q35226993 | Molecular mechanisms for generation of neural diversity and specificity: roles of polypeptide factors in development of postmitotic neurons |
| Q28291993 | Molecular mechanisms of fibroblast growth factor signaling in physiology and pathology |
| Q42807941 | Molecular modeling and deletion mutagenesis implicate the nuclear translocation sequence in structural integrity of fibroblast growth factor-1. |
| Q43197470 | Multimers of the fibroblast growth factor (FGF)-FGF receptor-saccharide complex are formed on long oligomers of heparin. |
| Q48048904 | Murine FGF-12 and FGF-13: expression in embryonic nervous system, connective tissue and heart. |
| Q40915825 | Mutations uncouple human fibroblast growth factor (FGF)-7 biological activity and receptor binding and support broad specificity in the secondary receptor binding site of FGFs. |
| Q40206704 | Nature of Interaction between basic fibroblast growth factor and the antiangiogenic drug 7,7-(carbonyl-bis[imino-N-methyl-4,2-pyrrolecarbonylimino[N-methyl-4,2-pyrrole]-carbonylimino])-bis-(1,3-naphtalene disulfonate). II. Removal of polar interacti |
| Q40125981 | Nature of interaction between basic fibroblast growth factor and the antiangiogenic drug 7,7-(Carbonyl-bis[imino-N-methyl-4, 2-pyrrolecarbonylimino[N-methyl-4,2-pyrrole]-carbonylimino] )bis-(1, 3-naphthalene disulfonate). |
| Q85054276 | Neovascularization by bFGF releasing hyaluronic acid–gelatin microspheres:in vitroandin vivostudies |
| Q43915145 | Neovascularization is associated with a switch to the export of bFGF in the multistep development of fibrosarcoma |
| Q30391563 | Neuritogenic and neuroprotective properties of peptide agonists of the fibroblast growth factor receptor |
| Q41205204 | Neurotrophic factors and the development of drugs to promote motoneuron survival |
| Q36077282 | Novel Bioluminescent Binding Assays for Ligand-Receptor Interaction Studies of the Fibroblast Growth Factor Family |
| Q34768206 | Numerous isoforms of Fgf8 reflect its multiple roles in the developing brain |
| Q48056266 | Of worms and men: an evolutionary perspective on the fibroblast growth factor (FGF) and FGF receptor families |
| Q36639272 | Oligomerization of acidic fibroblast growth factor is not a prerequisite for its cell proliferation activity. |
| Q38317243 | Oligomerization reduces heparin affinity but enhances receptor binding of fibroblast growth factor 2. |
| Q30369011 | Overview of protein folds in the immune system. |
| Q30368988 | Overview of protein structural and functional folds. |
| Q30524629 | Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2)-dependent oligomerization of fibroblast growth factor 2 (FGF2) triggers the formation of a lipidic membrane pore implicated in unconventional secretion. |
| Q43789253 | Platelet-derived growth factor-BB and basic fibroblast growth factor directly interact in vitro with high affinity |
| Q35773099 | Polyanions and the proteome |
| Q35058259 | Post-transcriptional regulation of interleukin 1 alpha in various strains of young and senescent human umbilical vein endothelial cells |
| Q33583925 | Preferential self-association of basic fibroblast growth factor is stabilized by heparin during receptor dimerization and activation. |
| Q34627120 | Rapamycin reverses hypertrophic cardiomyopathy in a mouse model of LEOPARD syndrome-associated PTPN11 mutation. |
| Q30194894 | Refinement of the structure of human basic fibroblast growth factor at 1.6 Å resolution and analysis of presumed heparin binding sites by selenate substitution |
| Q67700876 | Retinoic acid potentiates interleukin-1- and fibroblast growth factor-induced human synovial fibroblast proliferation |
| Q41337500 | Ribozymes: structure, function, and potential therapy for dominant genetic disorders |
| Q40205574 | Role of constraint in catalysis and high-affinity binding by proteins |
| Q38172600 | Role of fibroblast growth factors in elicitation of cell responses |
| Q34489556 | Role of heparan sulfate in fibroblast growth factor signalling: a structural view |
| Q28280225 | S100A13 is involved in the regulation of fibroblast growth factor-1 and p40 synaptotagmin-1 release in vitro |
| Q24301821 | S100A13 mediates the copper-dependent stress-induced release of IL-1α from both human U937 and murine NIH 3T3 cells |
| Q24654691 | Secretion without Golgi |
| Q43678259 | Sequence analyses and comparative modeling of fly and worm fibroblast growth factor receptors indicate that the determinants for FGF and heparin binding are retained in evolution |
| Q34425256 | Signaling by fibroblast growth factors: the inside story |
| Q38309317 | Solution NMR structure of a human FGF-1 monomer, activated by a hexasaccharide heparin-analogue. |
| Q74086594 | Solution structure and interaction with basic and acidic fibroblast growth factor of a 3-kDa human platelet factor-4 fragment with antiangiogenic activity |
| Q38327325 | Solution structure of human acidic fibroblast growth factor and interaction with heparin-derived hexasaccharide |
| Q68213278 | Stabilization of basic fibroblast growth factor with dextran sulfate |
| Q64252462 | Structural Biology of the FGF7 Subfamily |
| Q55919452 | Structural and Functional Diversity in the FGf Receptor Multigene Family |
| Q22010544 | Structural basis for FGF receptor dimerization and activation |
| Q30168679 | Structural events during the refolding of an all beta-sheet protein |
| Q22011005 | Structural interactions of fibroblast growth factor receptor with its ligands |
| Q27729397 | Structural studies of the binding of the anti-ulcer drug sucrose octasulfate to acidic fibroblast growth factor |
| Q90209793 | Structurally conserved binding motifs of transcriptional regulators to notch nuclear effector CSL |
| Q36449477 | Structure and function of the heparin-binding (fibroblast) growth factor family |
| Q27636303 | Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a β-trefoil |
| Q30278887 | Structure of BbKI, a disulfide-free plasma kallikrein inhibitor |
| Q38327052 | Structure of a heparan sulphate oligosaccharide that binds to basic fibroblast growth factor |
| Q27745966 | Structure of benzyl T-antigen disaccharide bound to Amaranthus caudatus agglutinin |
| Q27642163 | Structure of hisactophilin is similar to interleukin-1 beta and fibroblast growth factor |
| Q27643740 | Structure of rat acidic fibroblast growth factor at 1.4 Å resolution |
| Q60302361 | Structure, activation and dysregulation of fibroblast growth factor receptor kinases: perspectives for clinical targeting |
| Q38314372 | Sucralfate and soluble sucrose octasulfate bind and stabilize acidic fibroblast growth factor |
| Q42271414 | Susceptibility towards intramolecular disulphide-bond formation affects conformational stability and folding of human basic fibroblast growth factor |
| Q34325410 | Syndromic congenital sensorineural deafness, microtia and microdontia resulting from a novel homoallelic mutation in fibroblast growth factor 3 (FGF3). |
| Q42826671 | Synthesis and binding mode of heterocyclic analogues of suramin inhibiting the human basic fibroblast growth factor |
| Q73321071 | The AATPAP sequence is a very efficient signal for O-glycosylation in CHO cells |
| Q42814387 | The C-terminal region of fibroblast growth factor-1 is crucial for its biological activity and high level protein expression in mammalian cells |
| Q27732645 | The crystal structure of human glycosylation-inhibiting factor is a trimeric barrel with three 6-stranded beta-sheets |
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| Q42826176 | The importance of Arg40 and 45 in the mitogenic activity and structural stability of basic fibroblast growth factor: effects of acidic amino acid substitutions. |
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