Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members

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Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MCB.02249-06
P3181OpenCitations bibliographic resource ID1481499
P932PMC publication ID1899957
P698PubMed publication ID17339340
P5875ResearchGate publication ID6468100

P50authorRobert J. LinhardtQ7345927
Shaun K OlsenQ54253067
Regina GoetzQ57078008
Makoto Kuro-oQ88749584
Anna V EliseenkovaQ114419632
Hiroshi KurosuQ123475544
Moosa MohammadiQ37382162
Xijie YuQ38545234
P2093author name stringThomas A Neubert
Omar A Ibrahimi
Yasushi Ogawa
Beate Lanske
Juliya Kalinina
Steven A Kliewer
Fuming Zhang
Mohammed S Razzaque
Takeshi Inagaki
Kenneth E White
Masaya Yamamoto
Andrew Beenken
ChongFeng Xu
P2860cites workCrystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificityQ22254157
Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerizationQ24290400
Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23Q24290481
Structural basis by which alternative splicing confers specificity in fibroblast growth factor receptorsQ24294933
Kinetic model for FGF, FGFR, and proteoglycan signal transduction complex assemblyQ44850723
A novel mutation in fibroblast growth factor 23 gene as a cause of tumoral calcinosisQ46609225
Circulating intestinal fibroblast growth factor 19 has a pronounced diurnal variation and modulates hepatic bile acid synthesis in man.Q51485180
Mutant FGF-23 responsible for autosomal dominant hypophosphatemic rickets is resistant to proteolytic cleavage and causes hypophosphatemia in vivo.Q53964449
Structural basis by which alternative splicing modulates the organizer activity of FGF8 in the brainQ24300036
Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesisQ24305561
Mutation of the mouse klotho gene leads to a syndrome resembling ageingQ24328782
FGF-21 as a novel metabolic regulatorQ24523933
Fibroblast growth factorsQ24542507
Identification of receptor and heparin binding sites in fibroblast growth factor 4 by structure-based mutagenesisQ24550863
Crystal structure of fibroblast growth factor 9 reveals regions implicated in dimerization and autoinhibitionQ27627811
Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifsQ27636426
The crystal structure of fibroblast growth factor (FGF) 19 reveals novel features of the FGF family and offers a structural basis for its unusual receptor affinityQ27642980
Structural studies of the binding of the anti-ulcer drug sucrose octasulfate to acidic fibroblast growth factorQ27729397
Stereochemical quality of protein structure coordinatesQ27860874
Autosomal-dominant hypophosphatemic rickets (ADHR) mutations stabilize FGF-23Q28209679
Three-Dimensional Structures of Acidic and Basic Fibroblast Growth FactorsQ28267322
Klotho converts canonical FGF receptor into a specific receptor for FGF23Q28272505
beta-Trefoil fold. Patterns of structure and sequence in the Kunitz inhibitors interleukins-1 beta and 1 alpha and fibroblast growth factorsQ28294610
Fibroblast growth factor signaling during early vertebrate developmentQ28305654
Homozygous ablation of fibroblast growth factor-23 results in hyperphosphatemia and impaired skeletogenesis, and reverses hypophosphatemia in Phex-deficient miceQ28507303
The glycine box: a determinant of specificity for fibroblast growth factorQ28574386
Regulation of fibroblast growth factor-23 signaling by klothoQ28587100
Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasisQ29619610
Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolismQ29620323
Impaired negative feedback suppression of bile acid synthesis in mice lacking betaKlothoQ33905745
Biochemical analysis of pathogenic ligand-dependent FGFR2 mutations suggests distinct pathophysiological mechanisms for craniofacial and limb abnormalitiesQ34074836
Transgenic mice expressing human fibroblast growth factor-19 display increased metabolic rate and decreased adiposityQ34123954
Structural basis for fibroblast growth factor receptor activationQ36111391
A protein canyon in the FGF-FGF receptor dimer selects from an à la carte menu of heparan sulfate motifsQ36254487
Functions and regulations of fibroblast growth factor signaling during embryonic developmentQ36282338
Mutations uncouple human fibroblast growth factor (FGF)-7 biological activity and receptor binding and support broad specificity in the secondary receptor binding site of FGFs.Q40915825
Premature aging-like phenotype in fibroblast growth factor 23 null mice is a vitamin D-mediated processQ42736434
Increased circulatory level of biologically active full-length FGF-23 in patients with hypophosphatemic rickets/osteomalaciaQ44203982
Klotho is a novel beta-glucuronidase capable of hydrolyzing steroid beta-glucuronidesQ44710659
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
P304page(s)3417-28
P577publication date2007-05-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleMolecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members
P478volume27

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cites work (P2860)
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Q36977082beta-Klotho and FGF-15/19 inhibit the apical sodium-dependent bile acid transporter in enterocytes and cholangiocytes
Q50001744α-Klotho is a non-enzymatic molecular scaffold for FGF23 hormone signalling

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