| scholarly article | Q13442814 |
| review article | Q7318358 |
| P2093 | author name string | Nobuyuki Itoh | |
| P2860 | cites work | Structure and expression of a novel human FGF, FGF-19, expressed in the fetal brain | Q22001492 |
| FGF-19, a novel fibroblast growth factor with unique specificity for FGFR4 | Q22010687 | ||
| Identification of a novel FGF, FGF-21, preferentially expressed in the liver | Q22254289 | ||
| Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23 | Q24290481 | ||
| betaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c | Q24306279 | ||
| Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21 | Q24318639 | ||
| Polypeptide GalNAc-transferase T3 and familial tumoral calcinosis. Secretion of fibroblast growth factor 23 requires O-glycosylation | Q24321247 | ||
| Mutation of the mouse klotho gene leads to a syndrome resembling ageing | Q24328782 | ||
| FGF-21 as a novel metabolic regulator | Q24523933 | ||
| Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting | Q24563197 | ||
| Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia | Q24623628 | ||
| The FGF23-Klotho axis: endocrine regulation of phosphate homeostasis | Q24625902 | ||
| FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response | Q24653481 | ||
| Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family | Q24676527 | ||
| BetaKlotho is required for metabolic activity of fibroblast growth factor 21 | Q24681531 | ||
| Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members | Q24683254 | ||
| A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders | Q28116120 | ||
| Identification of a novel fibroblast growth factor, FGF-23, preferentially expressed in the ventrolateral thalamic nucleus of the brain | Q28141252 | ||
| Klotho, a gene related to a syndrome resembling human premature aging, functions in a negative regulatory circuit of vitamin D endocrine system | Q28207490 | ||
| Autosomal-dominant hypophosphatemic rickets (ADHR) mutations stabilize FGF-23 | Q28209679 | ||
| Functional evolutionary history of the mouse Fgf gene family | Q28259938 | ||
| Mutations in GALNT3, encoding a protein involved in O-linked glycosylation, cause familial tumoral calcinosis | Q28260847 | ||
| Klotho converts canonical FGF receptor into a specific receptor for FGF23 | Q28272505 | ||
| High expression of the bile salt-homeostatic hormone fibroblast growth factor 19 in the liver of patients with extrahepatic cholestasis | Q28308011 | ||
| Regulation of fibroblast growth factor-23 signaling by klotho | Q28587100 | ||
| Fibroblast growth factor homologous factors control neuronal excitability through modulation of voltage-gated sodium channels | Q28588873 | ||
| Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4 | Q28590891 | ||
| Fgf15 is required for proper morphogenesis of the mouse cardiac outflow tract | Q28593240 | ||
| Torpor induction in mammals: recent discoveries fueling new ideas | Q28749655 | ||
| Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states | Q29615208 | ||
| Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21 | Q29615209 | ||
| Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis | Q29619610 | ||
| Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism | Q29620323 | ||
| Hyperostosis-hyperphosphatemia syndrome: a congenital disorder of O-glycosylation associated with augmented processing of fibroblast growth factor 23. | Q33264714 | ||
| Fgf19 is required for zebrafish lens and retina development. | Q46843980 | ||
| The zebrafish fgf family | Q48076292 | ||
| Impaired hippocampal synaptic transmission and plasticity in mice lacking fibroblast growth factor 14. | Q48316842 | ||
| Fibroblast growth factor 21 regulates lipolysis in white adipose tissue but is not required for ketogenesis and triglyceride clearance in liver. | Q51421300 | ||
| Physiology. Sister act. | Q51469908 | ||
| Molecular cloning and expression analyses of mouse betaklotho, which encodes a novel Klotho family protein. | Q52163868 | ||
| DMP1 mutations in autosomal recessive hypophosphatemia implicate a bone matrix protein in the regulation of phosphate homeostasis. | Q54943458 | ||
| Fgf genes in the basal chordate Ciona intestinalis | Q58455573 | ||
| Relevant use of Klotho in FGF19 subfamily signaling system in vivo | Q33667883 | ||
| Regulation of insulin-like growth factor-I in starvation and injury. | Q33706591 | ||
| Impaired negative feedback suppression of bile acid synthesis in mice lacking betaKlotho | Q33905745 | ||
| Circulating concentration of FGF-23 increases as renal function declines in patients with chronic kidney disease, but does not change in response to variation in phosphate intake in healthy volunteers | Q33974129 | ||
| Fibroblast growth factor 21-deficient mice demonstrate impaired adaptation to ketosis | Q34019712 | ||
| The hepatic response to FGF19 is impaired in patients with nonalcoholic fatty liver disease and insulin resistance. | Q34094150 | ||
| Transgenic mice expressing human fibroblast growth factor-19 display increased metabolic rate and decreased adiposity | Q34123954 | ||
| A novel fibroblast growth factor gene expressed in the developing nervous system is a downstream target of the chimeric homeodomain oncoprotein E2A-Pbx1. | Q34440327 | ||
| Circulating FGF-21 levels in normal subjects and in newly diagnose patients with Type 2 diabetes mellitus | Q34699946 | ||
| Evolution of the Fgf and Fgfr gene families | Q35913683 | ||
| Fibroblast growth factor homologous factors: evolution, structure, and function | Q36111411 | ||
| Functions and regulations of fibroblast growth factor signaling during embryonic development | Q36282338 | ||
| Wnts as ligands: processing, secretion and reception | Q36672661 | ||
| Pathogenic role of Fgf23 in Dmp1-null mice. | Q36846110 | ||
| The FGF family: biology, pathophysiology and therapy | Q36933339 | ||
| Inhibition of growth hormone signaling by the fasting-induced hormone FGF21. | Q36953853 | ||
| The Fgf families in humans, mice, and zebrafish: their evolutional processes and roles in development, metabolism, and disease | Q36961346 | ||
| Ablation of the Galnt3 gene leads to low-circulating intact fibroblast growth factor 23 (Fgf23) concentrations and hyperphosphatemia despite increased Fgf23 expression | Q37210780 | ||
| Endocrine FGFs and Klothos: emerging concepts | Q37240464 | ||
| The role of bone in phosphate metabolism | Q37281226 | ||
| Endocrine fibroblast growth factors as regulators of metabolic homeostasis | Q37423215 | ||
| FGF21: a novel prospect for the treatment of metabolic diseases. | Q37428992 | ||
| Molecular pathology of the fibroblast growth factor family | Q37475258 | ||
| FGFs and metabolism | Q37580556 | ||
| Plasma concentrations of fibroblast growth factors 21 and 19 in patients with Cushing's syndrome. | Q38351425 | ||
| Fibroblast growth factor-21 improves pancreatic beta-cell function and survival by activation of extracellular signal-regulated kinase 1/2 and Akt signaling pathways. | Q40239037 | ||
| An FGF23 missense mutation causes familial tumoral calcinosis with hyperphosphatemia. | Q40482177 | ||
| Fgf21 is essential for haematopoiesis in zebrafish | Q42408104 | ||
| FGF-21/FGF-21 receptor interaction and activation is determined by betaKlotho | Q42819634 | ||
| Molecular determinants of FGF-21 activity-synergy and cross-talk with PPARgamma signaling | Q42834234 | ||
| FGF21 is dispensable for hypothermia induced by fasting in mice | Q43083439 | ||
| Fibroblast growth factor 19 serum levels: relation to renal function and metabolic parameters | Q43219382 | ||
| Serum concentrations and tissue expression of a novel endocrine regulator fibroblast growth factor-21 in patients with type 2 diabetes and obesity. | Q43287114 | ||
| Fibroblast growth factor 21 reduces the severity of cerulein-induced pancreatitis in mice | Q43296116 | ||
| FGF-23 in patients with end-stage renal disease on hemodialysis | Q44846350 | ||
| Identification of a recurrent mutation in GALNT3 demonstrates that hyperostosis-hyperphosphatemia syndrome and familial tumoral calcinosis are allelic disorders | Q45187805 | ||
| Plasma concentrations of fibroblast growth factors 19 and 21 in patients with anorexia nervosa. | Q46535466 | ||
| Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans | Q46770146 | ||
| Fgf19 regulated by Hh signaling is required for zebrafish forebrain development. | Q46779528 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | hormone | Q11364 |
| cancer | Q12078 | ||
| peptide hormone | Q416997 | ||
| peptide | Q172847 | ||
| molecular evolution | Q856529 | ||
| neoplasm | Q1216998 | ||
| metabolic disease | Q2351083 | ||
| P304 | page(s) | 1-11 | |
| P577 | publication date | 2010-08-24 | |
| 2010-10-01 | |||
| P1433 | published in | Cell and Tissue Research | Q1524113 |
| P1476 | title | Hormone-like (endocrine) Fgfs: their evolutionary history and roles in development, metabolism, and disease | |
| P478 | volume | 342 |
| Q51308109 | A computationally identified compound antagonizes excess FGF-23 signaling in renal tubules and a mouse model of hypophosphatemia. |
| Q97883357 | Adapting to the Cold: A Role for Endogenous Fibroblast Growth Factor 21 in Thermoregulation? |
| Q36886578 | An FGF21-adiponectin-ceramide axis controls energy expenditure and insulin action in mice |
| Q57463121 | An Ultradian Feeding Schedule in Rats Affects Metabolic Gene Expression in Liver, Brown Adipose Tissue and Skeletal Muscle with Only Mild Effects on Circadian Clocks |
| Q34806589 | Association between Serum Atypical Fibroblast Growth Factors 21 and 19 and Pediatric Nonalcoholic Fatty Liver Disease |
| Q46886117 | Biophysical constraints on the evolution of tissue structure and function |
| Q45966817 | Blockade of nonhormonal fibroblast growth factors by FP-1039 inhibits growth of multiple types of cancer. |
| Q21135215 | Circulating fibroblast growth factor 21 levels are closely associated with hepatic fat content: a cross-sectional study |
| Q38004610 | Control of asymmetric cell division of mammalian neural progenitors. |
| Q92043470 | Cross-Talk between Fibroblast Growth Factor Receptors and Other Cell Surface Proteins |
| Q45222692 | Cynomolgus monkey gallbladder bile contains high concentrations of fibroblast growth factor 19. |
| Q39766116 | Developmentally regulated expression of intracellular Fgf11-13, hormone-like Fgf15 and canonical Fgf16, -17 and -20 mRNAs in the developing mouse molar tooth |
| Q38631707 | Effect of circulating glucagon and free fatty acids on hepatic FGF21 production in dairy cows |
| Q58329363 | Effects of a high milk intake during the pre-weaning period on nutrient metabolism and growth rate in Japanese Black cattle |
| Q37737986 | Elucidating fish oil-induced milk fat depression in dairy sheep: Milk somatic cell transcriptome analysis |
| Q26781556 | Endocrine FGFs: Evolution, Physiology, Pathophysiology, and Pharmacotherapy |
| Q36856371 | Exenatide decreases hepatic fibroblast growth factor 21 resistance in non-alcoholic fatty liver disease in a mouse model of obesity and in a randomised controlled trial. |
| Q41933095 | FGF receptor antagonism does not affect adipose tissue development in nutritionally induced obesity |
| Q38098144 | FGF, TGFβ and Wnt crosstalk: embryonic to in vitro cartilage development from mesenchymal stem cells |
| Q34005504 | FGF-2 deficiency does not influence FGF ligand and receptor expression during development of the nigrostriatal system |
| Q42176870 | FGF21 as an Endocrine Regulator in Lipid Metabolism: From Molecular Evolution to Physiology and Pathophysiology |
| Q28485347 | FGF21 requires βklotho to act in vivo |
| Q38728860 | FGF23 from bench to bedside. |
| Q91410209 | FGF23 induced left ventricular hypertrophy mediated by FGFR4 signaling in the myocardium is attenuated by soluble Klotho in mice |
| Q36818730 | Feeding a Modified Fish Diet to Bottlenose Dolphins Leads to an Increase in Serum Adiponectin and Sphingolipids |
| Q41861232 | Fgf signaling in adipocytes as a target for metabolic diseases |
| Q38811850 | Fgf3-Fgf4-cis: A new mouse line for studying Fgf functions during mouse development. |
| Q27686803 | Fibroblast Growth Factor 21 Analogs for Treating Metabolic Disorders |
| Q38794405 | Fibroblast Growth Factor 21 As an Emerging Therapeutic Target for Type 2 Diabetes Mellitus |
| Q26766528 | Fibroblast Growth Factor 21 Protects against Atherosclerosis via Fine-Tuning the Multiorgan Crosstalk |
| Q88238584 | Fibroblast Growth Factor 23 is Associated With Adiposity in Patients Receiving Hemodialysis: Possible Cross Talk Between Bone and Adipose Tissue |
| Q26772751 | Fibroblast Growth Factor Signaling in Metabolic Regulation |
| Q93204977 | Fibroblast growth factor 21 facilitates peripheral nerve regeneration through suppressing oxidative damage and autophagic cell death |
| Q35266374 | Fibroblast growth factor 21 induces glucose transporter-1 expression through activation of the serum response factor/Ets-like protein-1 in adipocytes |
| Q35770027 | Fibroblast growth factor 21: a novel metabolic regulator |
| Q41779344 | Fibroblast growth factor 23 (FGF23) and alpha-klotho stimulate osteoblastic MC3T3.E1 cell proliferation and inhibit mineralization |
| Q48891787 | Fibroblast growth factor 23 signaling in hippocampal cells: impact on neuronal morphology and synaptic density. |
| Q36486182 | Fibroblast growth factor-19 action in the brain reduces food intake and body weight and improves glucose tolerance in male rats. |
| Q64973345 | Fibroblast growth factors 19 and 21 in acute liver damage. |
| Q35020888 | Fibroblast growth factors: from molecular evolution to roles in development, metabolism and disease |
| Q28729024 | Fundamentals of FGF19 & FGF21 action in vitro and in vivo |
| Q39332689 | Genomic organization and modulation of gene expression of the TGF-β and FGF pathways in the allotetraploid frog Xenopus laevis |
| Q39156563 | Impact of Fibroblast Growth Factors 19 and 21 in Bariatric Metabolism. |
| Q37168681 | Implication of fibroblast growth factors in epileptogenesis-associated circuit rearrangements |
| Q42857128 | Increased FGF21 plasma levels in humans with sepsis and SIRS. |
| Q37457703 | Inhibition of FGF/FGFR autocrine signaling in mesothelioma with the FGF ligand trap, FP-1039/GSK3052230. |
| Q50592611 | Instability restricts signaling of multiple fibroblast growth factors. |
| Q26823319 | Inventing new medicines: The FGF21 story |
| Q33751398 | Is fibroblast growth factor receptor 4 a suitable target of cancer therapy? |
| Q35854796 | Mapping the growth hormone--Stat5b--IGF-I transcriptional circuit |
| Q33685319 | Metabolic role of fibroblast growth factor 21 in liver, adipose and nervous system tissues |
| Q55490578 | Molecular elements in FGF19 and FGF21 defining KLB/FGFR activity and specificity. |
| Q37312020 | Multiple faces of fibroblast growth factor-23 |
| Q28541582 | Osteocyte-specific deletion of Fgfr1 suppresses FGF23 |
| Q33985578 | Palifermin for the protection and regeneration of epithelial tissues following injury: new findings in basic research and pre-clinical models |
| Q26853186 | Pathophysiological roles of FGF signaling in the heart |
| Q48107382 | Pharmacokinetics, tissue distribution and excretion of FGF-21 following subcutaneous administration in rats. |
| Q38241685 | Progenitor genealogy in the developing cerebral cortex |
| Q37612433 | REV-ERBα regulates Fgf21 expression in the liver via hepatic nuclear factor 6. |
| Q28487909 | Rational design of a fibroblast growth factor 21-based clinical candidate, LY2405319 |
| Q26860470 | Regulation and function of the FGF23/klotho endocrine pathways |
| Q28070054 | Regulation of fibroblast growth factor 15/19 and 21 on metabolism: in the fed or fasted state |
| Q55315635 | Role of Fibroblast Growth Factor-23 in Innate Immune Responses. |
| Q34408855 | Roles of FGFs as Adipokines in Adipose Tissue Development, Remodeling, and Metabolism |
| Q92025196 | Serum FGF21 Levels in Obese Korean Children and Adolescents |
| Q37106431 | Serum fibroblast growth factor 19 levels are decreased in Chinese subjects with impaired fasting glucose and inversely associated with fasting plasma glucose levels |
| Q36009264 | Signaling in cell differentiation and morphogenesis |
| Q46243742 | Single nucleotide polymorphisms in fibroblast growth factor 23 gene, FGF23, are associated with prostate cancer risk |
| Q37849781 | Targeting fibroblast-growth-factor-receptor-dependent signaling for cancer therapy. |
| Q34467171 | The Fibroblast Growth Factor signaling pathway |
| Q30234616 | The Role and Potential Therapeutic Implications of the Fibroblast Growth Factors in Energy Balance and Type 2 Diabetes |
| Q87569131 | The association between KL polymorphism and prostate cancer risk in Korean patients |
| Q41912342 | The breadth of FGF21's metabolic actions are governed by FGFR1 in adipose tissue |
| Q34219880 | The human gallbladder secretes fibroblast growth factor 19 into bile: towards defining the role of fibroblast growth factor 19 in the enterobiliary tract. |
| Q55513236 | The role of FGF21 in type 1 diabetes and its complications. |
| Q36992839 | The role of Klotho in energy metabolism |
| Q26823032 | The roles of fibroblast growth factors in the testicular development and tumor |
| Q38633258 | Therapeutic potential of the endocrine fibroblast growth factors FGF19, FGF21 and FGF23. |
| Q38706553 | Towards the next generation of biomedicines by site-selective conjugation |
| Q41884092 | Vgll2a is required for neural crest cell survival during zebrafish craniofacial development. |
| Q38591061 | Vitamin D: a dynamic molecule. How relevant might the dynamism for a vitamin be? |
| Q37506713 | Vitamin D: calcium and bone homeostasis during evolution |
| Q86277253 | [FGF23 and the heart] |
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