Association between Serum Atypical Fibroblast Growth Factors 21 and 19 and Pediatric Nonalcoholic Fatty Liver Disease

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Association between Serum Atypical Fibroblast Growth Factors 21 and 19 and Pediatric Nonalcoholic Fatty Liver Disease is …
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scholarly articleQ13442814

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P819ADS bibcode2013PLoSO...867160A
P356DOI10.1371/JOURNAL.PONE.0067160
P932PMC publication ID3694051
P698PubMed publication ID23840612
P5875ResearchGate publication ID248385777

P50authorAnna AlisiQ42430617
Nadia PaneraQ56507690
Valerio NobiliQ56507694
Cristiano De StefanisQ57040866
Sara CeccarelliQ58423082
Giorgio BedogniQ61784732
Alberto VillaniQ98201697
Marco PezzulloQ114454585
P2093author name stringStefania Petrini
Federica Prono
Alberto Tozzi
P2860cites workCirculating fibroblast growth factor 21 levels are closely associated with hepatic fat content: a cross-sectional studyQ21135215
Fibroblast growth factor 21: from pharmacology to physiologyQ24658126
Physiology of FGF15/19Q28261385
Klotho endows hepatoma cells with resistance to anoikis via VEGFR2/PAK1 activation in hepatocellular carcinomaQ28287609
Regulation of amphiregulin gene expression by β-catenin signaling in human hepatocellular carcinoma cells: a novel crosstalk between FGF19 and the EGFR systemQ28484499
FGF21 requires βklotho to act in vivoQ28485347
Fundamentals of FGF19 & FGF21 action in vitro and in vivoQ28729024
Design and validation of a histological scoring system for nonalcoholic fatty liver diseaseQ29614930
Systematic review of risk factors for fibrosis progression in non-alcoholic steatohepatitisQ30448524
The hepatic response to FGF19 is impaired in patients with nonalcoholic fatty liver disease and insulin resistance.Q34094150
Fibroblast growth factor 19 increases metabolic rate and reverses dietary and leptin-deficient diabetes.Q34300009
Fibroblast growth factor 21 corrects obesity in miceQ34805555
Pediatric nonalcoholic fatty liver disease, metabolic syndrome and cardiovascular riskQ35171570
Nrf2 represses FGF21 during long-term high-fat diet-induced obesity in miceQ35227185
The Klotho gene family as a regulator of endocrine fibroblast growth factorsQ37343638
FGFs and metabolismQ37580556
Pediatric nonalcoholic fatty liver disease in 2009.Q37601653
Hormone-like (endocrine) Fgfs: their evolutionary history and roles in development, metabolism, and diseaseQ37781747
Non-alcoholic fatty liver disease and metabolic syndrome in adolescents: pathogenetic role of genetic background and intrauterine environmentQ37847587
Regulation of ion channels by secreted KlothoQ37991260
Circulating fibroblast growth factors as metabolic regulators--a critical appraisalQ38065349
TNF-α represses β-Klotho expression and impairs FGF21 action in adipose cells: involvement of JNK1 in the FGF21 pathwayQ39317227
Differential specificity of endocrine FGF19 and FGF21 to FGFR1 and FGFR4 in complex with KLB.Q39374896
Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese miceQ43224118
Fibroblast growth factor 21 (FGF-21) and its relation to obesity, metabolic syndrome, and nonalcoholic fatty liver in children: a longitudinal analysisQ43577294
Waist circumference correlates with liver fibrosis in children with non-alcoholic steatohepatitisQ46792569
Italian cross-sectional growth charts for height, weight and BMI (6-20 y).Q47192450
Restoration of klotho expression induces apoptosis and autophagy in hepatocellular carcinoma cells.Q54279104
Preliminary evidence of a reduced serum level of fibroblast growth factor 19 in patients with biopsy-proven nonalcoholic fatty liver diseaseQ57116843
Nonalcoholic fatty liver disease in childrenQ62066966
Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokineQ63609769
Fibroblast growth factor-19 levels in type 2 diabetic patients with metabolic syndromeQ82939022
Pathology of nonalcoholic fatty liver diseaseQ83094715
Diagnosis of nonalcoholic fatty liver disease in children and adolescents: position paper of the ESPGHAN Hepatology CommitteeQ83583931
Fibroblast growth factor 21 as a biomarker for NAFLD: Integrating pathobiology into clinical practiceQ84962979
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectmetabolic dysfunction–associated steatotic liver diseaseQ1546498
P304page(s)e67160
P577publication date2013-06-26
P1433published inPLOS OneQ564954
P1476titleAssociation between Serum Atypical Fibroblast Growth Factors 21 and 19 and Pediatric Nonalcoholic Fatty Liver Disease
P478volume8

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Q37689828Diagnostic Value of CK-18, FGF-21, and Related Biomarker Panel in Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis
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