Relevant use of Klotho in FGF19 subfamily signaling system in vivo

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Relevant use of Klotho in FGF19 subfamily signaling system in vivo is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2010PNAS..107.1666T
P356DOI10.1073/PNAS.0913986107
P932PMC publication ID2824417
P698PubMed publication ID20080590
P5875ResearchGate publication ID41040257

P50authorYo-Ichi NabeshimaQ123476420
P2093author name stringKazuwa Nakao
Akihiro Imura
Yuji Yamazaki
Shinji Ito
Tomohiro Tanaka
Yoko Nabeshima
Itaru Urakawa
Kiminori Hosoda
Tsutomu Tomita
Shinji Odori
Ken-ichi Tomiyama
Ryota Maeda
P2860cites workStructure and expression of a novel human FGF, FGF-19, expressed in the fetal brainQ22001492
Identification of a novel FGF, FGF-21, preferentially expressed in the liverQ22254289
betaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3cQ24306279
Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21Q24318639
Liver-specific activities of FGF19 require Klotho betaQ24319088
Mutation of the mouse klotho gene leads to a syndrome resembling ageingQ24328782
FGF-21 as a novel metabolic regulatorQ24523933
FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation responseQ24653481
BetaKlotho is required for metabolic activity of fibroblast growth factor 21Q24681531
Fibroblast growth factors, their receptors and signalingQ28140520
The enzymes, regulation, and genetics of bile acid synthesisQ28204726
Klotho, a gene related to a syndrome resembling human premature aging, functions in a negative regulatory circuit of vitamin D endocrine systemQ28207490
Functional evolutionary history of the mouse Fgf gene familyQ28259938
Klotho converts canonical FGF receptor into a specific receptor for FGF23Q28272505
alpha-Klotho as a regulator of calcium homeostasisQ28306317
Regulation of fibroblast growth factor-23 signaling by klothoQ28587100
Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4Q28590891
Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic statesQ29615208
Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21Q29615209
A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesisQ29617241
Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasisQ29619610
Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolismQ29620323
Impaired negative feedback suppression of bile acid synthesis in mice lacking betaKlothoQ33905745
Co-receptor requirements for fibroblast growth factor-19 signalingQ34665759
Evolution of the Fgf and Fgfr gene familiesQ35913683
alpha-Klotho: a regulator that integrates calcium homeostasisQ37045462
Mini-review: endocrine actions of fibroblast growth factor 19.Q37052076
Fibroblast growth factor 21 controls glycemia via regulation of hepatic glucose flux and insulin sensitivityQ37328872
1alpha,25-Dihydroxyvitamin D3 upregulates FGF23 gene expression in bone: the final link in a renal-gastrointestinal-skeletal axis that controls phosphate transportQ40397501
FGF-21/FGF-21 receptor interaction and activation is determined by betaKlothoQ42819634
Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese miceQ43224118
Fibroblast growth factor 21 regulates lipolysis in white adipose tissue but is not required for ketogenesis and triglyceride clearance in liver.Q51421300
Molecular cloning and expression analyses of mouse betaklotho, which encodes a novel Klotho family protein.Q52163868
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)1666-1671
P577publication date2010-01-08
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleRelevant use of Klotho in FGF19 subfamily signaling system in vivo
P478volume107