Osteo-renal regulation of systemic phosphate metabolism

scientific article

Osteo-renal regulation of systemic phosphate metabolism is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1002/IUB.437
P932PMC publication ID3120048
P698PubMed publication ID21438115
P5875ResearchGate publication ID50852440

P2093author name stringMohammed Shawkat Razzaque
P2860cites workAutosomal dominant hypophosphataemic rickets is associated with mutations in FGF23Q24290481
Osteocyte control of bone formation via sclerostin, a novel BMP antagonistQ24300347
Identification of the human klotho gene and its two transcripts encoding membrane and secreted klotho proteinQ24309454
FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasisQ24319751
The FGF23-Klotho axis: endocrine regulation of phosphate homeostasisQ24625902
FGF23-mediated regulation of systemic phosphate homeostasis: is Klotho an essential player?Q24653541
Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily membersQ24683254
Identification of a novel fibroblast growth factor, FGF-23, preferentially expressed in the ventrolateral thalamic nucleus of the brainQ28141252
FGF-23-Klotho signaling stimulates proliferation and prevents vitamin D-induced apoptosisQ28289695
Sclerostin inhibition of Wnt-3a-induced C3H10T1/2 cell differentiation is indirect and mediated by bone morphogenetic proteinsQ28293474
FGF23 fails to inhibit uremic parathyroid glandsQ28579798
Increased parathyroid expression of klotho in uremic ratsQ28583360
Intestinal npt2b plays a major role in phosphate absorption and homeostasisQ33561684
In vivo genetic evidence for suppressing vascular and soft-tissue calcification through the reduction of serum phosphate levels, even in the presence of high serum calcium and 1,25-dihydroxyvitamin d levelsQ33572351
Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formationQ33591785
Mineral metabolism and aging: the fibroblast growth factor 23 enigmaQ33982618
FGF23 decreases renal NaPi-2a and NaPi-2c expression and induces hypophosphatemia in vivo predominantly via FGF receptor 1.Q34017992
Dietary and genetic evidence for phosphate toxicity accelerating mammalian agingQ34072221
Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubuleQ34072230
Disease model: human agingQ34207950
Proximal tubular handling of phosphate: A molecular perspectiveQ34563763
Initial FGF23-mediated signaling occurs in the distal convoluted tubuleQ34695191
Klotho: a fundamental regulator of agingQ34936976
STUDIES OF CALCIUM AND PHOSPHORUS METABOLISM : V. A STUDY OF THE BONE TRABECULAE AS A READILY AVAILABLE RESERVE SUPPLY OF CALCIUMQ35010142
Osteocalcin: a pivotal mediator or an innocent bystander in energy metabolism?Q35025454
The dualistic role of vitamin D in vascular calcificationsQ35059753
Phosphate toxicity: new insights into an old problemQ35059905
Molecular regulation of phosphate metabolism by fibroblast growth factor-23-klotho systemQ35059924
Atomic structure of intracellular amorphous calcium phosphate depositsQ35080791
Reversal of mineral ion homeostasis and soft-tissue calcification of klotho knockout mice by deletion of vitamin D 1alpha-hydroxylaseQ35126790
Inorganic phosphate as a signaling molecule in osteoblast differentiationQ35541291
Crosstransplantation of kidneys in normal and Hyp mice. Evidence that the Hyp mouse phenotype is unrelated to an intrinsic renal defectQ35601830
A homozygous missense mutation in human KLOTHO causes severe tumoral calcinosisQ35925637
Regulation of phosphorus homeostasis by the type iia na/phosphate cotransporterQ36191092
Structural and biochemical properties of fibroblast growth factor 23.Q36216956
Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17Q36288869
Klotho as a regulator of fibroblast growth factor signaling and phosphate/calcium metabolismQ36507256
Novel dosage forms and regimens for sevelamer-based phosphate bindersQ36529334
FGF23: its role in renal bone diseaseQ36577606
The kidney and bone metabolism: Nephrologists' point of view.Q36638034
Phosphate transporters: a tale of two solute carrier families.Q36854464
The emerging role of the fibroblast growth factor-23-klotho axis in renal regulation of phosphate homeostasisQ36860289
The fallacy of the calcium-phosphorus productQ36869798
High dietary inorganic phosphate increases lung tumorigenesis and alters Akt signalingQ37041944
alpha-Klotho: a regulator that integrates calcium homeostasisQ37045462
In vivo genetic evidence for klotho-dependent, fibroblast growth factor 23 (Fgf23) -mediated regulation of systemic phosphate homeostasisQ37072412
Hypophosphatemia with elevations in serum fibroblast growth factor 23 in a child with Jansen's metaphyseal chondrodysplasiaQ37072659
Does Fgf23-klotho activity influence vascular and soft tissue calcification through regulating mineral ion metabolism?Q37182735
Disorders of calcium, phosphorus and magnesium metabolism.Q37340047
The roles of Na/Pi-II transporters in phosphate metabolismQ37397812
Inactivation of klotho function induces hyperphosphatemia even in presence of high serum fibroblast growth factor 23 levels in a genetically engineered hypophosphatemic (Hyp) mouse modelQ37415834
Calcium and phosphorus homeostasisQ37418629
FGF23 and the parathyroid glandsQ37762995
Consequences of phosphate imbalanceQ39548605
1alpha,25-Dihydroxyvitamin D3 upregulates FGF23 gene expression in bone: the final link in a renal-gastrointestinal-skeletal axis that controls phosphate transportQ40397501
An FGF23 missense mutation causes familial tumoral calcinosis with hyperphosphatemia.Q40482177
Transgenic mice overexpressing human fibroblast growth factor 23 (R176Q) delineate a putative role for parathyroid hormone in renal phosphate wasting disordersQ40530218
Cellular/molecular control of renal Na/Pi-cotransportQ41743339
Klotho and Na+,K+-ATPase activity: solving the calcium metabolism dilemma?Q41900414
No bones about it: insulin modulates skeletal remodelingQ42959815
Does FGF23 toxicity influence the outcome of chronic kidney disease?Q43078080
Sevelamer attenuates the progression of coronary and aortic calcification in hemodialysis patientsQ44039636
Changes in serum calcium, phosphate, and PTH and the risk of death in incident dialysis patients: a longitudinal studyQ44278022
Randomized, double-blind, placebo-controlled, dose-titration, phase III study assessing the efficacy and tolerability of lanthanum carbonate: a new phosphate binder for the treatment of hyperphosphatemiaQ44493980
Priliminary trial of low doses of human parathyroid hormone 1-34 peptide in treatment of osteoporosisQ44867219
Severe hyperphosphatemia and hypocalcemia following the rectal administration of a phosphate-containing Fleet pediatric enemaQ44962321
High plasma phosphate as a risk factor for decline in renal function and mortality in pre-dialysis patientsQ44977753
Vitamin D and phosphate regulate fibroblast growth factor-23 in K-562 cellsQ45238632
Klotho ablation converts the biochemical and skeletal alterations in FGF23 (R176Q) transgenic mice to a Klotho-deficient phenotypeQ46264351
Intracellular precipitation of hydroxyapatite mineral and implications for pathologic calcification.Q46277651
Inhibition of intestinal sodium-dependent inorganic phosphate transport by fibroblast growth factor 23.Q46631798
Effects of sevelamer and calcium on coronary artery calcification in patients new to hemodialysisQ46704866
Fibroblast growth factor-23 regulates parathyroid hormone and 1alpha-hydroxylase expression in cultured bovine parathyroid cellsQ46970328
Aluminium poisoning: dialysis encephalopathy, osteomalacia, and anaemiaQ48778417
Severely reduced production of klotho in human chronic renal failure kidneyQ49064415
Renal transplantation in hypophosphatemia with vitamin D-resistant rickets.Q54421161
DMP1 mutations in autosomal recessive hypophosphatemia implicate a bone matrix protein in the regulation of phosphate homeostasis.Q54943458
Calcium, phosphorus, parathyroid hormone, and cardiovascular disease in hemodialysis patients: the USRDS waves 1, 3, and 4 studyQ64111823
Fatal poisoning from sodium phosphate enema. Case report and experimental studyQ68967880
Intracellular mineralization of Bacterionema matruchotiiQ70789287
A fatal small dose of phosphate enema in a young child with no renal or gastrointestinal abnormalityQ73498176
Randomised controlled study of effect of parathyroid hormone on vertebral-bone mass and fracture incidence among postmenopausal women on oestrogen with osteoporosisQ73668443
Fatal hyperphosphatemia after oral phosphate overdose in a premature infantQ73851838
Intermittent doxercalciferol (1alpha-hydroxyvitamin D(2)) therapy for secondary hyperparathyroidismQ74288772
Calcium, phosphate, and parathyroid hormone levels in combination and as a function of dialysis duration predict mortality: evidence for the complexity of the association between mineral metabolism and outcomesQ76378411
In vivo mechanisms of hydroxyapatite ceramic degradation by osteoclasts: Fine structural microscopyQ79288079
Mortality effect of coronary calcification and phosphate binder choice in incident hemodialysis patientsQ79478108
Trends and dynamics of changes in calcification score over the 1-year observation period in patients on peritoneal dialysisQ80497742
Parathyroid hormone regulates fibroblast growth factor-23 in a mouse model of primary hyperparathyroidismQ81251002
Klotho, FGF23, and FGF receptors in chronic kidney disease: a yin-yang situation?Q82452774
Inflammation, mineral metabolism and progressive coronary artery calcification in patients on haemodialysisQ82915984
The secretory response of parathyroid hormone to acute hypocalcemia in vivo is independent of parathyroid glandular sodium/potassium-ATPase activityQ83137716
Toward a better understanding of KlothoQ83283214
P433issue4
P304page(s)240-247
P577publication date2011-03-24
P1433published inIUBMB LifeQ15764029
P1476titleOsteo-renal regulation of systemic phosphate metabolism
P478volume63

Reverse relations

cites work (P2860)
Q37244863Can features of phosphate toxicity appear in normophosphatemia?
Q37498019Can salivary phosphate levels be an early biomarker to monitor the evolvement of obesity?
Q35003219Dietary and genetic evidence for enhancing glucose metabolism and reducing obesity by inhibiting klotho functions
Q24187142Dietary interventions for mineral and bone disorder in people with chronic kidney disease
Q24201392Dietary interventions for mineral and bone disorder in people with chronic kidney disease
Q28085476Dysregulation of phosphate metabolism and conditions associated with phosphate toxicity
Q36504367Entpd5 is essential for skeletal mineralization and regulates phosphate homeostasis in zebrafish.
Q38087548FGF23 associated bone diseases
Q43074642FGF23-induced hypophosphatemia persists in Hyp mice deficient in the WNT coreceptor Lrp6.
Q36992835Genetic induction of phosphate toxicity significantly reduces the survival of hypercholesterolemic obese mice
Q28535055Inadequate awareness among chronic kidney disease patients regarding food and drinks containing artificially added phosphate
Q64231913Lack of Awareness of Dietary Sources of Phosphorus Is a Clinical Concern
Q34119083Lack of awareness among future medical professionals about the risk of consuming hidden phosphate-containing processed food and drinks
Q42656868Targeted Pth4-expressing cell ablation impairs skeletal mineralization in zebrafish
Q37485598The First Scube3 Mutant Mouse Line with Pleiotropic Phenotypic Alterations.
Q37493998The rachitic tooth
Q36992839The role of Klotho in energy metabolism
Q36976545Toward improved phosphorus efficiency in monogastrics-interplay of serum, minerals, bone, and immune system after divergent dietary phosphorus supply in swine
Q38633152Vitamin D, phosphate, and vasculotoxicity.

Search more.