scholarly article | Q13442814 |
P2093 | author name string | M Shawkat Razzaque | |
Mutsuko Ohnishi | |||
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In vivo genetic evidence for suppressing vascular and soft-tissue calcification through the reduction of serum phosphate levels, even in the presence of high serum calcium and 1,25-dihydroxyvitamin d levels | Q33572351 | ||
Increased superoxide in vivo accelerates age-associated muscle atrophy through mitochondrial dysfunction and neuromuscular junction degeneration | Q34329795 | ||
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Lack of methionine sulfoxide reductase A in mice increases sensitivity to oxidative stress but does not diminish life span | Q37355376 | ||
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Aging, fertility, and immortality | Q46541301 | ||
Immunohistochemical localization of Klotho protein in brain, kidney, and reproductive organs of mice | Q49122089 | ||
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Life-long suppression of growth hormone-insulin-like growth factor I activity in genetically altered rats could prevent age-related renal damage | Q80228977 | ||
Correlation between hyperphosphatemia and type II Na-Pi cotransporter activity in klotho mice | Q80294165 | ||
FGF-23, vitamin D and calcification: the unholy triad | Q80394650 | ||
Poor maternal nutrition followed by accelerated postnatal growth leads to telomere shortening and increased markers of cell senescence in rat islets | Q83153230 | ||
P433 | issue | 9 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | toxicity | Q274160 |
P304 | page(s) | 3562-3571 | |
P577 | publication date | 2010-04-23 | |
P1433 | published in | FASEB Journal | Q520194 |
P1476 | title | Dietary and genetic evidence for phosphate toxicity accelerating mammalian aging | |
P478 | volume | 24 |
Q36019820 | A High Phosphorus Diet Affects Lipid Metabolism in Rat Liver: A DNA Microarray Analysis |
Q42727584 | A phosphate-centric paradigm for pathophysiology and therapy of chronic kidney disease |
Q21131156 | A review of the nonpressor and nonantidiuretic actions of the hormone vasopressin |
Q37062520 | Accelerated ageing and renal dysfunction links lower socioeconomic status and dietary phosphate intake |
Q26863412 | Calcium regulation and bone mineral metabolism in elderly patients with chronic kidney disease |
Q33986838 | Calpain 1 inhibitor BDA-410 ameliorates α-klotho-deficiency phenotypes resembling human aging-related syndromes |
Q37244863 | Can features of phosphate toxicity appear in normophosphatemia? |
Q37498019 | Can salivary phosphate levels be an early biomarker to monitor the evolvement of obesity? |
Q55344982 | Circulating markers of ageing and allostatic load: A slow train coming. |
Q92128969 | Dietary Care for ADPKD Patients: Current Status and Future Directions |
Q35003219 | Dietary and genetic evidence for enhancing glucose metabolism and reducing obesity by inhibiting klotho functions |
Q52743002 | Dietary phosphate modifies lifespan in Drosophila. |
Q35590824 | Dietary phosphate restriction normalizes biochemical and skeletal abnormalities in a murine model of tumoral calcinosis |
Q90029481 | Dietary vitamin D interacts with high phosphate-induced cardiac remodeling in rats with normal renal function |
Q37801814 | Disorders of phosphorus homeostasis |
Q38985548 | Downregulation of kidney protective factors by inflammation: role of transcription factors and epigenetic mechanisms |
Q64231827 | Dysregulated Phosphate Metabolism, Periodontal Disease, and Cancer: Possible Global Health Implications |
Q28085476 | Dysregulation of phosphate metabolism and conditions associated with phosphate toxicity |
Q46286178 | Effects of extracellular phosphate on gene expression in murine osteoblasts |
Q90665075 | Examining the association between serum phosphate levels and leukocyte telomere length |
Q34639537 | FGF-23 as a Predictor of Renal Outcome in Diabetic Nephropathy |
Q43074642 | FGF23-induced hypophosphatemia persists in Hyp mice deficient in the WNT coreceptor Lrp6. |
Q90426138 | FGFR4 does not contribute to progression of chronic kidney disease |
Q30544587 | Fibroblast growth factor 23 and Klotho: physiology and pathophysiology of an endocrine network of mineral metabolism |
Q27011668 | Fibroblast growth factor signaling in the vasculature |
Q34788510 | Genetic ablation of sfrp4 in mice does not affect serum phosphate homeostasis. |
Q34631633 | Genetic determinants of phosphate response in Drosophila |
Q36992835 | Genetic induction of phosphate toxicity significantly reduces the survival of hypercholesterolemic obese mice |
Q34985917 | Heat shock protein 47: a novel biomarker of phenotypically altered collagen-producing cells |
Q99711241 | High Phosphate Induces and Klotho Attenuates Kidney Epithelial Senescence and Fibrosis |
Q50459213 | Histochemical Examination on Periodontal Tissues of Klotho-Deficient Mice Fed With Phosphate-Insufficient Diet |
Q98892056 | How metabolic acidosis and kidney disease may accelerate the aging process |
Q57051343 | Hyperphosphatemia Promotes Senescence of Myoblasts by Impairing Autophagy Through Ilk Overexpression, A Possible Mechanism Involved in Sarcopenia |
Q46313956 | Hyperphosphatemia induces senescence in human endothelial cells by increasing endothelin-1 production. |
Q92302556 | Impact of Subtotal Parathyroidectomy on Clinical Parameters and Quality of Life in Hemodialysis Patients with Secondary Hyperparathyroidism |
Q42920083 | In search of the fountain of youth |
Q28535055 | Inadequate awareness among chronic kidney disease patients regarding food and drinks containing artificially added phosphate |
Q58747343 | Increased Phosphaturia Accelerates The Decline in Renal Function: A Search for Mechanisms |
Q38671509 | Initiation of Sevelamer and Mortality among Hemodialysis Patients Treated with Calcium-Based Phosphate Binders. |
Q40974207 | Inorganic Phosphate Activates the AKT/mTORC1 Pathway and Shortens the Life Span of an α‑Klotho-Deficient Model |
Q41832808 | Inorganic phosphate in the development and treatment of cancer: A Janus Bifrons? |
Q34283091 | Inorganic phosphate induces cancer cell mediated angiogenesis dependent on forkhead box protein C2 (FOXC2) regulated osteopontin expression |
Q38185277 | Intestinal phosphate transport: a therapeutic target in chronic kidney disease and beyond? |
Q104615239 | Investigation of the transforming growth factor-beta 1 signalling pathway as a possible link between hyperphosphataemia and renal fibrosis in feline chronic kidney disease |
Q35033538 | Klotho and the aging process |
Q38115124 | Klotho, phosphate and FGF-23 in ageing and disturbed mineral metabolism |
Q27013965 | Klotho, phosphate and inflammation/ageing in chronic kidney disease |
Q26783185 | Klotho, stem cells, and aging |
Q38842162 | Klotho, the Holy Grail of the kidney: from salt sensitivity to chronic kidney disease |
Q64231913 | Lack of Awareness of Dietary Sources of Phosphorus Is a Clinical Concern |
Q34119083 | Lack of awareness among future medical professionals about the risk of consuming hidden phosphate-containing processed food and drinks |
Q38865416 | Magnesium modifies the association between serum phosphate and the risk of progression to end-stage kidney disease in patients with non-diabetic chronic kidney disease |
Q60921741 | Magnesium: Are We Consuming Enough? |
Q37883149 | Mechanism by which chronic kidney disease causes cardiovascular disease and the measures to manage this phenomenon |
Q89442831 | Mechanisms and Regulation of Intestinal Phosphate Absorption |
Q90040434 | Modifying Phosphate Toxicity in Chronic Kidney Disease |
Q35441666 | Molecular basis of Klotho: from gene to function in aging |
Q35059924 | Molecular regulation of phosphate metabolism by fibroblast growth factor-23-klotho system |
Q38213502 | Next-generation phosphate binders: focus on iron-based binders |
Q35059741 | Osteo-renal regulation of systemic phosphate metabolism |
Q35417067 | PTH ablation ameliorates the anomalies of Fgf23-deficient mice by suppressing the elevated vitamin D and calcium levels |
Q61443406 | Parathyroid hormone and premature thymus ageing in patients with chronic kidney disease |
Q47196589 | Parathyroidectomy in chronic kidney disease: effects on weight gain and on quality of life improvement |
Q30449841 | Pathological features in the LmnaDhe/+ mutant mouse provide a novel model of human otitis media and laminopathies |
Q48199124 | Pathophysiology and therapeutics of premature ageing in chronic kidney disease, with a focus on glycative stress. |
Q35546322 | Phosphate Metabolism in Cardiorenal Metabolic Disease |
Q37984042 | Phosphate additives in food--a health risk |
Q35679883 | Phosphate and Klotho |
Q54096437 | Phosphate stimulates myotube atrophy through autophagy activation: evidence of hyperphosphatemia contributing to skeletal muscle wasting in chronic kidney disease. |
Q35059905 | Phosphate toxicity: new insights into an old problem |
Q51766352 | Phosphate-Catalyzed Succinimide Formation from Asp Residues: A Computational Study of the Mechanism. |
Q36620380 | Phosphate-Induced Renal Fibrosis Requires the Prolyl Isomerase Pin1 |
Q27325653 | Protective roles of DMP1 in high phosphate homeostasis |
Q92940669 | Recent Advances in Models, Mechanisms, Biomarkers, and Interventions in Cisplatin-Induced Acute Kidney Injury |
Q46734017 | Regulation of mineral metabolism by lithium |
Q36672616 | Renal and extrarenal actions of Klotho |
Q27021975 | Renal fibrosis in feline chronic kidney disease: known mediators and mechanisms of injury |
Q90631576 | Research Models for Studying Vascular Calcification |
Q35318410 | Role of Klotho in aging, phosphate metabolism, and CKD. |
Q34168361 | Roles of major facilitator superfamily transporters in phosphate response in Drosophila |
Q38200883 | Roles of phosphate and fibroblast growth factor 23 in cardiovascular disease. |
Q38745657 | Serum Phosphorus and Risk of Cardiovascular Disease, All-Cause Mortality, or Graft Failure in Kidney Transplant Recipients: An Ancillary Study of the FAVORIT Trial Cohort |
Q58711341 | Serum phosphate and phosphate-regulatory hormones in COPD patients |
Q57418622 | Serum phosphate levels are related to all-cause, cardiovascular and COPD mortality in men |
Q38152465 | Significance of the anti-aging protein Klotho |
Q38097347 | Sodium phosphate as an ergogenic aid. |
Q36280331 | Targeted deletion of Klotho in kidney distal tubule disrupts mineral metabolism. |
Q38703771 | Targeting local vascular and systemic consequences of inflammation on vascular and cardiac valve calcification |
Q49282725 | The age-related changes of dietary phosphate responsiveness in plasma 1,25-dihydroxyvitamin D levels and renal Cyp27b1 and Cyp24a1 gene expression is associated with renal α-Klotho gene expression in mice |
Q45185006 | The demise of calcium-based phosphate binders |
Q35059753 | The dualistic role of vitamin D in vascular calcifications |
Q34260105 | The kidney is the principal organ mediating klotho effects |
Q36992839 | The role of Klotho in energy metabolism |
Q34337575 | The role of the gastrointestinal tract in phosphate homeostasis in health and chronic kidney disease |
Q35784205 | The role of vitamin D in the FGF23, klotho, and phosphate bone-kidney endocrine axis |
Q90551011 | Untangling the thread of life spun by αKlotho |
Q38633152 | Vitamin D, phosphate, and vasculotoxicity. |
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