Increased parathyroid expression of klotho in uremic rats

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Increased parathyroid expression of klotho in uremic rats is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1006464967
P356DOI10.1038/KI.2010.215
P698PubMed publication ID20631679

P50authorKlaus ØlgaardQ42529530
Ewa LewinQ89717378
P2093author name stringMartin A Santini
Jacob Hofman-Bang
Giedre Martuseviciene
P2860cites workCellular signaling by fibroblast growth factor receptorsQ24301087
Mutation of the mouse klotho gene leads to a syndrome resembling ageingQ24328782
Klotho, a gene related to a syndrome resembling human premature aging, functions in a negative regulatory circuit of vitamin D endocrine systemQ28207490
Fibroblast growth factor 23 impairs phosphorus and vitamin D metabolism in vivo and suppresses 25-hydroxyvitamin D-1alpha-hydroxylase expression in vitroQ28240791
Klotho converts canonical FGF receptor into a specific receptor for FGF23Q28272505
The Klotho gene family and the endocrine fibroblast growth factorsQ28288742
alpha-Klotho as a regulator of calcium homeostasisQ28306317
Parathyroid cell resistance to fibroblast growth factor 23 in secondary hyperparathyroidism of chronic kidney diseaseQ28583746
Regulation of fibroblast growth factor-23 signaling by klothoQ28587100
Reversal of mineral ion homeostasis and soft-tissue calcification of klotho knockout mice by deletion of vitamin D 1alpha-hydroxylaseQ35126790
Regulation of 1,25-dihydroxyvitamin D3 receptor gene expression by 1,25-dihydroxyvitamin D3 in the parathyroid in vivoQ35817684
A homozygous missense mutation in human KLOTHO causes severe tumoral calcinosisQ35925637
Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1Q36775194
FGFR3 and FGFR4 do not mediate renal effects of FGF23.Q36985772
Fibroblast growth factor 23 acts on the parathyroid to decrease parathyroid hormone secretionQ37228151
Indirect regulation of PTH by estrogens may require FGF23.Q37330544
The Klotho gene family as a regulator of endocrine fibroblast growth factorsQ37343638
Novel mechanisms in the regulation of phosphorus homeostasisQ37386445
FGF23-parathyroid interaction: implications in chronic kidney diseaseQ37654689
The beta-glucuronidase klotho hydrolyzes and activates the TRPV5 channelQ40359636
Klotho and Na+,K+-ATPase activity: solving the calcium metabolism dilemma?Q41900414
Autoregulation in the parathyroid glands by PTH/PTHrP receptor ligands in normal and uremic ratsQ42442443
Mediation of unusually high concentrations of 1,25-dihydroxyvitamin D in homozygous klotho mutant mice by increased expression of renal 1alpha-hydroxylase geneQ43858025
Simultaneous changes in the calcium-sensing receptor and the vitamin D receptor under the influence of calcium and calcitriolQ46537782
Fibroblast growth factor-23 regulates parathyroid hormone and 1alpha-hydroxylase expression in cultured bovine parathyroid cellsQ46970328
Immunohistochemical localization of Klotho protein in brain, kidney, and reproductive organs of miceQ49122089
Involvement of alpha-klotho and fibroblast growth factor receptor in the development of secondary hyperparathyroidismQ50073496
Mineralized tissue cells are a principal source of FGF23.Q51992228
Depressed expression of Klotho and FGF receptor 1 in hyperplastic parathyroid glands from uremic patients.Q54711237
Fibroblast Growth Factor 23 (FGF23) Predicts Progression of Chronic Kidney Disease: The Mild to Moderate Kidney Disease (MMKD) StudyQ59575076
Effects of ouabain on [3H]ouabain binding, 86Rb uptake, cellular sodium and potassium, and parathyroid hormone secretion in dispersed bovine parathyroid cellsQ71762758
1,25(OH)2D3 only affects long-term levels of plasma Ca2+ but not the rapid minute-to-minute plasma Ca2+ homeostasis in the ratQ73021967
Proliferation of parathyroid cells negatively correlates with expression of parathyroid hormone-related protein in secondary parathyroid hyperplasiaQ77807636
Regulation of fibroblast growth factor-23 in chronic kidney diseaseQ80474977
Type I membrane klotho expression is decreased and inversely correlated to serum calcium in primary hyperparathyroidismQ81746919
Persistent alpha-Klotho (a-Kl) expression in the parathyroid glands of patients with secondary hyperparathyroidismQ82520623
Klotho, an important new factor for the activity of Ca2+ channels, connecting calcium homeostasis, ageing and uraemiaQ83181302
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)1119-1127
P577publication date2010-07-14
P1433published inKidney InternationalQ6404823
P1476titleIncreased parathyroid expression of klotho in uremic rats
P478volume78