scholarly article | Q13442814 |
P819 | ADS bibcode | 2005Sci...310..490C |
P356 | DOI | 10.1126/SCIENCE.1114245 |
P698 | PubMed publication ID | 16239475 |
P5875 | ResearchGate publication ID | 7527980 |
P2093 | author name string | Chang Q | |
Bindels RJ | |||
Hoenderop JG | |||
van der Kemp AW | |||
Hoefs S | |||
Topala CN | |||
P433 | issue | 5747 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 490-493 | |
P577 | publication date | 2005-10-01 | |
P1433 | published in | Science | Q192864 |
P1476 | title | The beta-glucuronidase klotho hydrolyzes and activates the TRPV5 channel | |
P478 | volume | 310 |
Q42214079 | A helix-breaking mutation in the epithelial Ca(2+) channel TRPV5 leads to reduced Ca(2+)-dependent inactivation |
Q24309111 | A missense mutation in the Kv1.1 voltage-gated potassium channel-encoding gene KCNA1 is linked to human autosomal dominant hypomagnesemia |
Q46182549 | A population of selected renal cells augments renal function and extends survival in the ZSF1 model of progressive diabetic nephropathy |
Q43072181 | A sensitive gel-based method combining distinct cyclophellitol-based probes for the identification of acid/base residues in human retaining β-glucosidases. |
Q37943014 | A spoonful of sugar makes the melanoma go: the role of heparan sulfate proteoglycans in melanoma metastasis. |
Q36491105 | A translocation causing increased alpha-klotho level results in hypophosphatemic rickets and hyperparathyroidism |
Q47794863 | Ablation of klotho and premature aging: is 1,25-dihydroxyvitamin D the key middleman? |
Q35574809 | Ablation of the p16(INK4a) tumour suppressor reverses ageing phenotypes of klotho mice |
Q37319469 | Active Ca(2+) reabsorption in the connecting tubule |
Q55089216 | Acute Adaption to Oral or Intravenous Phosphate Requires Parathyroid Hormone. |
Q43239627 | Age-dependent changes in the expression of klotho protein, TRPV5 and TRPV6 in mouse inner ear. |
Q37459100 | Ageing and vitamin D deficiency: effects on calcium homeostasis and considerations for vitamin D supplementation |
Q38348935 | Aging and uremia: Is there cellular and molecular crossover? |
Q57751778 | Agonistic β-Klotho antibody mimics fibroblast growth factor 21 (FGF21) functions |
Q44037637 | Altered regulation of cytosolic Ca²⁺ concentration in dendritic cells from klotho hypomorphic mice |
Q38454084 | Angiotensin II blockade: how its molecular targets may signal to mitochondria and slow aging. Coincidences with calorie restriction and mTOR inhibition |
Q36049831 | Antiaging gene Klotho enhances glucose-induced insulin secretion by up-regulating plasma membrane levels of TRPV2 in MIN6 β-cells |
Q26827655 | Arterial calcification in chronic kidney disease: key roles for calcium and phosphate |
Q37404983 | Biochemical and functional characterization of the klotho-VS polymorphism implicated in aging and disease risk |
Q26777149 | Biological Role of Anti-aging Protein Klotho |
Q47989110 | Biology of Fibroblast Growth Factor 23: From Physiology to Pathology |
Q37195350 | Bone disease in pediatric idiopathic hypercalciuria |
Q37082368 | Calciotropic and magnesiotropic TRP channels |
Q48038085 | Calcium Homeostasis in Health and in Kidney Disease |
Q37091865 | Calcium and phosphate homeostasis: concerted interplay of new regulators |
Q26863412 | Calcium regulation and bone mineral metabolism in elderly patients with chronic kidney disease |
Q37072422 | Calcium-permeable ion channels in the kidney |
Q38585448 | Capacitation-Associated Glycocomponents of Mammalian Sperm |
Q36479676 | Cardioprotection by Klotho through downregulation of TRPC6 channels in the mouse heart |
Q100440285 | Changes in Fibroblast Growth Factor 23 and Soluble Klotho Levels After Hemodialysis Initiation |
Q37483194 | Changes in Serum Concentrations of Fibroblast Growth Factor 23 and Soluble Klotho in Hemodialysis Patients after Total Parathyroidectomy. |
Q51104948 | Comparative proteome analysis of wild-type and klotho-knockout mouse kidneys using a combination of MALDI-IMS and LC-MS/MS. |
Q37405002 | Complex N-glycosylation stabilizes surface expression of transient receptor potential melastatin 4b protein |
Q35912924 | Conditional Deletion of Fgfr1 in the Proximal and Distal Tubule Identifies Distinct Roles in Phosphate and Calcium Transport. |
Q33374711 | Conditional fast expression and function of multimeric TRPV5 channels using Shield-1. |
Q50460870 | Coordinated regulation of TRPV5-mediated Ca²⁺ transport in primary distal convolution cultures. |
Q35210184 | Cross talk between the renin-angiotensin-aldosterone system and vitamin D-FGF-23-klotho in chronic kidney disease |
Q37087785 | Current understanding of klotho |
Q83177528 | Decreased renal α-Klotho expression in early diabetic nephropathy in humans and mice and its possible role in urinary calcium excretion |
Q52689816 | Deficient transient receptor potential vanilloid type 4 function contributes to compromised [Ca2+]i homeostasis in human autosomal-dominant polycystic kidney disease cells. |
Q57717034 | Dehydration: a new modulator of klotho expression |
Q27333726 | Deletion of PTH rescues skeletal abnormalities and high osteopontin levels in Klotho-/- mice |
Q35841012 | Deregulated Renal Calcium and Phosphate Transport during Experimental Kidney Failure |
Q38302200 | Development and characterization of monoclonal antibodies to detect klotho |
Q35003219 | Dietary and genetic evidence for enhancing glucose metabolism and reducing obesity by inhibiting klotho functions |
Q36472485 | Discovery of alpha-Klotho unveiled new insights into calcium and phosphate homeostasis |
Q48821290 | Disorders of calcium metabolism |
Q34629804 | Distal convoluted tubule |
Q52975643 | Distal convoluted tubule. |
Q34299107 | Down-regulation of Intestinal Apical Calcium Entry Channel TRPV6 by Ubiquitin E3 Ligase Nedd4-2 |
Q36016804 | Dynamics and Distribution of Klothoβ (KLB) and fibroblast growth factor receptor-1 (FGFR1) in living cells reveal the fibroblast growth factor-21 (FGF21)-induced receptor complex |
Q41345368 | Effects of N-Glycosylation of the human cation channel TRPA1 on agonist-sensitivity. |
Q90812884 | Elevated FGF23 and disordered renal mineral handling with reduced bone mineralization in chronically erythropoietin over-expressing transgenic mice |
Q34005604 | Endocrine regulation of ageing |
Q37007210 | Expression and function of the HNK-1 carbohydrate. |
Q37318049 | Extracellular interactome of the FGF receptor-ligand system: complexities and the relative simplicity of the worm |
Q41774411 | Extracellular pH dynamically controls cell surface delivery of functional TRPV5 channels |
Q54960612 | FGF23 Actions on Target Tissues-With and Without Klotho. |
Q90105707 | FGF23 Synthesis and Activity |
Q42256983 | FGF23 acts directly on renal proximal tubules to induce phosphaturia through activation of the ERK1/2-SGK1 signaling pathway |
Q42878661 | FGF23 and Klotho: the new cornerstones of phosphate/calcium metabolism |
Q37996937 | FGF23 and PTH--double agents at the heart of CKD. |
Q37584801 | FGF23 and syndromes of abnormal renal phosphate handling |
Q36750178 | FGF23 as a calciotropic hormone |
Q38087548 | FGF23 associated bone diseases |
Q38728860 | FGF23 from bench to bedside. |
Q28509196 | FGF23 promotes renal calcium reabsorption through the TRPV5 channel |
Q36985772 | FGFR3 and FGFR4 do not mediate renal effects of FGF23. |
Q30544587 | Fibroblast growth factor 23 and Klotho: physiology and pathophysiology of an endocrine network of mineral metabolism |
Q93208168 | Fibroblast growth factor 23 and α-Klotho co-dependent and independent functions |
Q28570342 | Fibroblast growth factor 23 enhances renal klotho abundance |
Q28272364 | Fibroblast growth factors as tissue repair and regeneration therapeutics |
Q37598664 | Flow-induced activation of TRPV5 and TRPV6 channels stimulates Ca(2+)-activated K(+) channel causing membrane hyperpolarization |
Q38076051 | From bone abnormalities to mineral metabolism dysregulation in autosomal dominant polycystic kidney disease. |
Q39997971 | Function and regulation of the Na+-Ca2+ exchanger NCX3 splice variants in brain and skeletal muscle. |
Q39776568 | Functional analysis of the Kv1.1 N255D mutation associated with autosomal dominant hypomagnesemia. |
Q38072903 | Gastric acid, calcium absorption, and their impact on bone health |
Q36763582 | Genetic basis of renal cellular dysfunction and the formation of kidney stones |
Q38244118 | Genetic diseases of renal phosphate handling |
Q89161363 | Hyperphosphatemic familial tumoral calcinosis secondary to fibroblast growth factor 23 (FGF23) mutation: a report of two affected families and review of the literature |
Q30437039 | Identification of calcium-binding proteins associated with the human sperm plasma membrane |
Q38305115 | Identification of cleavage sites leading to the shed form of the anti-aging protein klotho |
Q35916097 | Impaired basolateral sorting of pro-EGF causes isolated recessive renal hypomagnesemia |
Q34780123 | Implications of Klotho in vascular health and disease. |
Q33572351 | In vivo genetic evidence for suppressing vascular and soft-tissue calcification through the reduction of serum phosphate levels, even in the presence of high serum calcium and 1,25-dihydroxyvitamin d levels |
Q28583360 | Increased parathyroid expression of klotho in uremic rats |
Q58798347 | Inhibition of Transient Receptor Potential Vanilloid 6 channel, elevated in human ovarian cancers, reduces tumour growth in a xenograft model |
Q52721559 | Interrelated role of Klotho and calcium-sensing receptor in parathyroid hormone synthesis and parathyroid hyperplasia. |
Q36740455 | Is Klotho deficiency independently associated with cardiovascular risk in chronic kidney disease? |
Q54382027 | KLOTHO gene polymorphism of G395A is associated with kidney stones. |
Q38181483 | Kidney and calcium homeostasis |
Q37591992 | Klotho |
Q38732756 | Klotho Lacks an FGF23-Independent Role in Mineral Homeostasis |
Q53595930 | Klotho RNAi induces premature senescence of human cells via a p53/p21 dependent pathway. |
Q51745509 | Klotho ameliorates sepsis-induced acute kidney injury but is irrelevant to autophagy. |
Q41900414 | Klotho and Na+,K+-ATPase activity: solving the calcium metabolism dilemma? |
Q24654902 | Klotho and aging |
Q38104935 | Klotho and chronic kidney disease |
Q35582566 | Klotho and kidney disease |
Q35033538 | Klotho and the aging process |
Q37051351 | Klotho as a regulator of oxidative stress and senescence |
Q35611229 | Klotho deficiency is an early biomarker of renal ischemia–reperfusion injury and its replacement is protective |
Q28287609 | Klotho endows hepatoma cells with resistance to anoikis via VEGFR2/PAK1 activation in hepatocellular carcinoma |
Q37678608 | Klotho has dual protective effects on cisplatin-induced acute kidney injury |
Q26775409 | Klotho in cardiovascular disease: Current and future perspectives |
Q34624546 | Klotho inhibits transforming growth factor-beta1 (TGF-beta1) signaling and suppresses renal fibrosis and cancer metastasis in mice |
Q42078322 | Klotho is a substrate for alpha-, beta- and gamma-secretase |
Q34320354 | Klotho is associated with VEGF receptor-2 and the transient receptor potential canonical-1 Ca 2+ channel to maintain endothelial integrity |
Q28480498 | Klotho lacks a vitamin D independent physiological role in glucose homeostasis, bone turnover, and steady-state PTH secretion in vivo |
Q88580595 | Klotho preservation by Rhein promotes toll-like receptor 4 proteolysis and attenuates lipopolysaccharide-induced acute kidney injury |
Q41989687 | Klotho prevents renal calcium loss. |
Q94600774 | Klotho rewires cellular metabolism of breast cancer cells through alteration of calcium shuttling and mitochondrial activity |
Q48626410 | Klotho sensitivity of the hERG channel |
Q54611511 | Klotho suppresses RIG-I-mediated senescence-associated inflammation. |
Q91555930 | Klotho suppresses colorectal cancer through modulation of the unfolded protein response |
Q34774466 | Klotho up-regulates renal calcium channel transient receptor potential vanilloid 5 (TRPV5) by intra- and extracellular N-glycosylation-dependent mechanisms |
Q37396631 | Klotho variants and chronic hemodialysis mortality |
Q26783185 | Klotho, stem cells, and aging |
Q38842162 | Klotho, the Holy Grail of the kidney: from salt sensitivity to chronic kidney disease |
Q28079797 | Klotho: a humeral mediator in CSF and plasma that influences longevity and susceptibility to multiple complex disorders, including depression |
Q35870769 | Klotho: a novel and early biomarker of acute kidney injury after cardiac valve replacement surgery in adults |
Q34072230 | Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule |
Q37858474 | Klotho: a novel regulator of calcium and phosphorus homeostasis |
Q39944675 | Klotho: a tumor suppressor and a modulator of the IGF-1 and FGF pathways in human breast cancer |
Q26799745 | Klotho: a tumor suppressor and modulator of the Wnt/β-catenin pathway in human hepatocellular carcinoma |
Q28291037 | Klotho: an antiaging protein involved in mineral and vitamin D metabolism |
Q35053874 | Klotho: its various functions and association with sickle cell disease subphenotypes |
Q46851255 | Laboratory aspects of circulating α-Klotho |
Q37384718 | Latest findings in phosphate homeostasis |
Q34252649 | Life extension factor klotho enhances cognition |
Q34462326 | Life extension factor klotho prevents mortality and enhances cognition in hAPP transgenic mice |
Q35813165 | Longevity factor klotho and chronic psychological stress |
Q34493922 | Loss of Klotho during melanoma progression leads to increased filamin cleavage, increased Wnt5A expression, and enhanced melanoma cell motility. |
Q36444555 | Low Plasma Klotho Concentrations and Decline of Knee Strength in Older Adults |
Q52934731 | Membrane-bound Klotho is not expressed endogenously in healthy or uraemic human vascular tissue. |
Q33982618 | Mineral metabolism and aging: the fibroblast growth factor 23 enigma |
Q37371915 | Mining the depths: metabolic insights into mineral nutrition |
Q38116835 | Modulation of voltage-gated ion channels by sialylation |
Q35441666 | Molecular basis of Klotho: from gene to function in aging |
Q37805923 | Molecular basis of epithelial Ca2+ and Mg2+ transport: insights from the TRP channel family |
Q37448279 | Molecular genetics of parathyroid disease. |
Q35059924 | Molecular regulation of phosphate metabolism by fibroblast growth factor-23-klotho system |
Q51016091 | Monitoring for potential residual disease activity by serum insulin-like growth factor 1 and soluble Klotho in patients with acromegaly after pituitary surgery: is there an impact of the genomic deletion of exon 3 in the growth hormone receptor (d3- |
Q30386353 | Mucin-1 Increases Renal TRPV5 Activity In Vitro, and Urinary Level Associates with Calcium Nephrolithiasis in Patients |
Q38287732 | N-glycan content modulates kainate receptor functional properties |
Q36052386 | N-glycosylation determines ionic permeability and desensitization of the TRPV1 capsaicin receptor. |
Q33652154 | N-glycosylation determines the abundance of the transient receptor potential channel TRPP2 |
Q41842547 | N-glycosylation in regulation of the nervous system |
Q39366129 | N-glycosylation of TRPM8 ion channels modulates temperature sensitivity of cold thermoreceptor neurons. |
Q47132894 | New Insights into the Mechanism of Action of Soluble Klotho |
Q36618101 | New insights into the pathogenesis of idiopathic hypercalciuria |
Q39378500 | Novel roles for mucin 1 in the kidney |
Q42541748 | Nuclear localization of Klotho in brain: an anti-aging protein |
Q37559361 | Overview of the FGF23-Klotho axis |
Q88062876 | P2X7 receptor and klotho expressions in diabetic nephropathy progression |
Q42945861 | Parathyroid Klotho and FGF-receptor 1 expression decline with renal function in hyperparathyroid patients with chronic kidney disease and kidney transplant recipients |
Q36425115 | Pathophysiology of the chronic kidney disease-mineral bone disorder |
Q35546322 | Phosphate Metabolism in Cardiorenal Metabolic Disease |
Q37224025 | Plasma Klotho and Cognitive Decline in Older Adults: Findings From the InCHIANTI Study |
Q92524220 | Plasma Klotho concentration is associated with the presence, burden and progression of cerebral small vessel disease in patients with acute ischaemic stroke |
Q36364310 | Plasma klotho and cardiovascular disease in adults |
Q46946131 | Plasma klotho and frailty in older adults: Findings from the InCHIANTI Study |
Q35127280 | Plasma klotho and mortality risk in older community-dwelling adults |
Q36800779 | Plasma soluble α-klotho protein levels in premature and term neonates: correlations with growth and metabolic parameters |
Q38327224 | Plasticity of renal endocrine function |
Q38203371 | Post-Translational Modifications of TRP Channels |
Q37126253 | Post-translational loss of renal TRPV5 calcium channel expression, Ca(2+) wasting, and bone loss in experimental colitis. |
Q53151181 | Potential Role of Placental Klotho in the Pathogenesis of Preeclampsia. |
Q40245905 | RGS2 inhibits the epithelial Ca2+ channel TRPV6. |
Q34260123 | Reduced renal calcium excretion in the absence of sclerostin expression: evidence for a novel calcium-regulating bone kidney axis. |
Q33492044 | Regulated and aberrant glycosylation modulate cardiac electrical signaling |
Q38016324 | Regulated expression and neural functions of human natural killer-1 (HNK-1) carbohydrate. |
Q26860470 | Regulation and function of the FGF23/klotho endocrine pathways |
Q36472107 | Regulation of TRPV5 and TRPV6 by associated proteins |
Q28279142 | Regulation of ion channels by secreted Klotho: mechanisms and implications |
Q36649088 | Regulation of phosphate homeostasis by PTH, vitamin D, and FGF23. |
Q37256511 | Regulation of phosphate transport in proximal tubules. |
Q24658068 | Regulation of renal outer medullary potassium channel and renal K(+) excretion by Klotho |
Q48672869 | Regulation of the Na+/K+ ATPase by Klotho |
Q36450027 | Regulation of transport in the connecting tubule and cortical collecting duct |
Q36212506 | Relationship of low plasma klotho with poor grip strength in older community-dwelling adults: the InCHIANTI study |
Q36775194 | Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1 |
Q36417890 | Renal Production, Uptake, and Handling of Circulating αKlotho |
Q35976038 | Renal adaptation to gentamicin-induced mineral loss |
Q36672616 | Renal and extrarenal actions of Klotho |
Q37201509 | Renal senescence in 2008: progress and challenges |
Q49865594 | Role of FGF23 in Pediatric Hypercalciuria |
Q35318410 | Role of Klotho in aging, phosphate metabolism, and CKD. |
Q36703547 | Role of renal TRP channels in physiology and pathology |
Q38420343 | Role of the transient receptor potential vanilloid 5 (TRPV5) protein N terminus in channel activity, tetramerization, and trafficking |
Q26768186 | Roles of the kidney in the formation, remodeling and repair of bone |
Q37190542 | Secreted klotho and chronic kidney disease |
Q38012604 | Sensing mechanisms involved in Ca2+ and Mg2+ homeostasis. |
Q36008059 | Serum 25-Hydroxyvitamin D, Plasma Klotho, and Lower-Extremity Physical Performance Among Older Adults: Findings From the InCHIANTI Study |
Q64117609 | Serum klotho: a potential predictor of cerebrovascular disease in hemodialysis patients |
Q45014648 | Serum levels of soluble secreted α-Klotho are decreased in the early stages of chronic kidney disease, making it a probable novel biomarker for early diagnosis |
Q38855334 | Shedding of klotho by ADAMs in the kidney |
Q38152465 | Significance of the anti-aging protein Klotho |
Q34394061 | Small-molecule Klotho enhancers as novel treatment of neurodegeneration |
Q35550609 | Soluble Klotho Protects against Uremic Cardiomyopathy Independently of Fibroblast Growth Factor 23 and Phosphate |
Q34941418 | Soluble Klotho is not independently associated with cardiovascular disease in a population of dialysis patients |
Q38861058 | Soluble extracellular Klotho decreases sensitivity to cigarette smoke induced cell death in human lung epithelial cells |
Q37612604 | Soluble klotho binds monosialoganglioside to regulate membrane microdomains and growth factor signaling |
Q91823533 | Soluble klotho regulates TRPC6 calcium signaling via lipid rafts, independent of the FGFR-FGF23 pathway |
Q33988884 | Soluble α-klotho as a novel biomarker in the early stage of nephropathy in patients with type 2 diabetes |
Q89473460 | Structure-function relationships of the soluble form of the antiaging protein Klotho have therapeutic implications for managing kidney disease |
Q37739046 | Systemic klotho is associated with KLOTHO variation and predicts intrinsic cortical connectivity in healthy human aging |
Q24312097 | TRP channel-associated factors are a novel protein family that regulates TRPM8 trafficking and activity |
Q29616673 | TRP channels |
Q38111283 | TRP channels |
Q35915824 | TRP channels and Ca2+ signaling |
Q37205820 | TRPV5: an ingeniously controlled calcium channel |
Q92383138 | TRPV6 as A Target for Cancer Therapy |
Q36280331 | Targeted deletion of Klotho in kidney distal tubule disrupts mineral metabolism. |
Q52905611 | Targeted deletion of murine Cldn16 identifies extra- and intrarenal compensatory mechanisms of Ca2+ and Mg2+ wasting. |
Q36933339 | The FGF family: biology, pathophysiology and therapy |
Q39006777 | The FGF23 and Klotho system beyond mineral metabolism. |
Q30836888 | The First Extracellular Linker Is Important for Several Aspects of the Gating Mechanism of Human TRPA1 Channel. |
Q93222971 | The Klotho proteins in health and disease |
Q44125135 | The Xenopus TRPV6 homolog encodes a Mg(2+) -permeant channel that is inhibited by interaction with TRPC1. |
Q38983596 | The aging suppressor klotho: a potential regulator of growth hormone secretion |
Q39979858 | The beta-glucuronidase klotho exclusively activates the epithelial Ca2+ channels TRPV5 and TRPV6. |
Q39101623 | The chronic kidney disease - Mineral bone disorder (CKD-MBD): Advances in pathophysiology |
Q34568579 | The cooperation of FGF receptor and Klotho is involved in excretory canal development and regulation of metabolic homeostasis in Caenorhabditis elegans. |
Q38545213 | The dynamic skeleton |
Q37710161 | The effect of nephrectomy on Klotho, FGF-23 and bone metabolism |
Q42666228 | The epithelial calcium channel TRPV5 is regulated differentially by klotho and sialidase |
Q34121153 | The identification of Histidine 712 as a critical residue for constitutive TRPV5 internalization |
Q48100012 | The impact of klotho gene polymorphisms on urinary tract stone disease. |
Q34260105 | The kidney is the principal organ mediating klotho effects |
Q50096271 | The klotho-related protein KLPH (lctl) has preferred expression in lens and is essential for expression of clic5 and normal lens suture formation |
Q38730521 | The neuroprotective effect of latanoprost acts via klotho-mediated suppression of calpain activation after optic nerve transection |
Q28572613 | The parathyroid is a target organ for FGF23 in rats |
Q37802467 | The renal connecting tubule: Resolved and unresolved issues in Ca2+ transport |
Q36992839 | The role of Klotho in energy metabolism |
Q57801450 | The role of klotho in chronic kidney disease |
Q38197055 | The role of protein N-glycosylation in neural transmission |
Q37527790 | The role of transient receptor potential channels in kidney disease |
Q39235785 | The role of vitamin D in the endocrinology controlling calcium homeostasis |
Q38774298 | Tissue kallikrein stimulates Ca(2+) reabsorption via PKC-dependent plasma membrane accumulation of TRPV5. |
Q85000782 | Tissue transglutaminase inhibits the TRPV5-dependent calcium transport in an N-glycosylation-dependent manner |
Q26849317 | Transient receptor potential channels as drug targets: from the science of basic research to the art of medicine |
Q36266724 | Tumor necrosis factor and interferon-gamma down-regulate Klotho in mice with colitis |
Q36979830 | Uromodulin upregulates TRPV5 by impairing caveolin-mediated endocytosis |
Q35204874 | Variation in longevity gene KLOTHO is associated with greater cortical volumes |
Q34621641 | Vitamin D: Metabolism, Molecular Mechanism of Action, and Pleiotropic Effects. |
Q24310130 | WNK3 positively regulates epithelial calcium channels TRPV5 and TRPV6 via a kinase-dependent pathway |
Q38786641 | Ways of calcium reabsorption in the kidney. |
Q37198480 | What do we know about the transient receptor potential vanilloid 2 (TRPV2) ion channel? |
Q39107200 | X-linked hypophosphatemia and growth. |
Q38842548 | Xeno-Klotho Inhibits Parathyroid Hormone Signaling |
Q86277253 | [FGF23 and the heart] |
Q50001744 | α-Klotho is a non-enzymatic molecular scaffold for FGF23 hormone signalling |
Q55263123 | α-Klotho's effects on mineral homeostasis are fibroblast growth factor-23 dependent. |
Q37758405 | β-Glucosidases. |
Q34073956 | β1-Adrenergic receptor signaling activates the epithelial calcium channel, transient receptor potential vanilloid type 5 (TRPV5), via the protein kinase A pathway |