FGF23 and the parathyroid glands

scientific article published on 05 June 2010

FGF23 and the parathyroid glands is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1007/S00467-010-1565-3
P698PubMed publication ID20526631

P2093author name stringJustin Silver
Tally Naveh-Many
P2860cites workAutosomal dominant hypophosphataemic rickets is associated with mutations in FGF23Q24290481
Fibroblast growth factor (FGF)-23 inhibits renal phosphate reabsorption by activation of the mitogen-activated protein kinase pathwayQ28198276
The parathyroid is a target organ for FGF23 in ratsQ28572613
Parathyroid cell resistance to fibroblast growth factor 23 in secondary hyperparathyroidism of chronic kidney diseaseQ28583746
Regulation of fibroblast growth factor-23 signaling by klothoQ28587100
Effects of cinacalcet and concurrent low-dose vitamin D on FGF23 levels in ESRD.Q33571321
Circulating fibroblast growth factor 23 in patients with end-stage renal disease treated by peritoneal dialysis is intact and biologically activeQ33736093
Fibroblast growth factor 23 and mortality among patients undergoing hemodialysisQ33932297
Fibroblast growth factor-23 and early decrements in kidney function: the Heart and Soul StudyQ33988990
Fibroblast growth factor-23 mitigates hyperphosphatemia but accentuates calcitriol deficiency in chronic kidney diseaseQ34557934
Initial FGF23-mediated signaling occurs in the distal convoluted tubuleQ34695191
Fibroblast growth factor-23 is the phosphaturic factor in tumor-induced osteomalacia and may be phosphatoninQ34726787
Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism.Q35728669
Postprandial mineral metabolism and secondary hyperparathyroidism in early CKDQ36667209
Endocrine functions of bone in mineral metabolism regulation.Q36982323
Hypophosphatemia with elevations in serum fibroblast growth factor 23 in a child with Jansen's metaphyseal chondrodysplasiaQ37072659
Patterns of FGF-23, DMP1, and MEPE expression in patients with chronic kidney diseaseQ37440758
Do osteocytes contribute to phosphate homeostasis?Q37485823
FGF23-parathyroid interaction: implications in chronic kidney diseaseQ37654689
Klotho prevents renal calcium loss.Q41989687
Fibroblast growth factor 23 is a counter-regulatory phosphaturic hormone for vitamin D.Q42493065
Premature aging-like phenotype in fibroblast growth factor 23 null mice is a vitamin D-mediated processQ42736434
Anti-FGF23 neutralizing antibodies show the physiological role and structural features of FGF23.Q44465622
Sinoatrial node dysfunction and early unexpected death of mice with a defect of klotho gene expressionQ44810019
Human PTH gene regulation in vivo using transgenic mice.Q45943472
High levels of serum fibroblast growth factor (FGF)-23 are associated with increased mortality in long haemodialysis patients.Q46035991
Relationship between circulating FGF23 and total body atherosclerosis in the communityQ46519355
Vitamin D receptor-independent FGF23 actions in regulating phosphate and vitamin D metabolismQ46585085
Fibroblast growth factor-23 regulates parathyroid hormone and 1alpha-hydroxylase expression in cultured bovine parathyroid cellsQ46970328
Secreted Klotho protein in sera and CSF: implication for post-translational cleavage in release of Klotho protein from cell membraneQ47627574
Involvement of alpha-klotho and fibroblast growth factor receptor in the development of secondary hyperparathyroidismQ50073496
Mutant FGF-23 responsible for autosomal dominant hypophosphatemic rickets is resistant to proteolytic cleavage and causes hypophosphatemia in vivo.Q53964449
Depressed expression of Klotho and FGF receptor 1 in hyperplastic parathyroid glands from uremic patients.Q54711237
Parathyroid hormone regulates fibroblast growth factor-23 in a mouse model of primary hyperparathyroidismQ81251002
Intravenous calcitriol therapy increases serum concentrations of fibroblast growth factor-23 in dialysis patients with secondary hyperparathyroidismQ81853118
Does the downregulation of the FGF23 signaling pathway in hyperplastic parathyroid glands contribute to refractory secondary hyperparathyroidism in CKD patients?Q82875571
P433issue11
P304page(s)2241-2245
P577publication date2010-06-05
P1433published inPediatric NephrologyQ15749796
P1476titleFGF23 and the parathyroid glands
P478volume25

Reverse relations

cites work (P2860)
Q47126125A Case of Hyperphosphatemia and Elevated Fibroblast Growth Factor 23: A Brief Review of Hyperphosphatemia and Fibroblast Growth Factor 23 Pathway
Q38348935Aging and uremia: Is there cellular and molecular crossover?
Q37984036Aldosterone and parathyroid hormone: a precarious couple for cardiovascular disease
Q34988878Association between circulating fibroblast growth factor 23, α-Klotho, and the left ventricular ejection fraction and left ventricular mass in cardiology inpatients
Q38257346Bone development and mineral homeostasis in the fetus and neonate: roles of the calciotropic and phosphotropic hormones
Q37938913Bone development: overview of bone cells and signaling.
Q83462650Decrease in serum FGF23 levels after intravenous infusion of pamidronate in patients with osteogenesis imperfecta
Q35841012Deregulated Renal Calcium and Phosphate Transport during Experimental Kidney Failure
Q34281991Erythroid promoter confines FGF2 expression to the marrow after hematopoietic stem cell gene therapy and leads to enhanced endosteal bone formation
Q49873034FGF23 Is Not Required to Regulate Fetal Phosphorus Metabolism but Exerts Effects Within 12 Hours After Birth
Q91697808FGF23 expression is stimulated in transgenic α-Klotho longevity mouse model
Q27013868Familial tumoral calcinosis: a valuable vehicle for discovery
Q64998522Hepatic Osteodystrophy-Molecular Mechanisms Proposed to Favor Its Development.
Q38103455Hypophosphatemic rickets due to perturbations in renal tubular function
Q38104935Klotho and chronic kidney disease
Q35683762Magnesium in chronic kidney disease Stages 3 and 4 and in dialysis patients
Q38737740Maternal Mineral and Bone Metabolism During Pregnancy, Lactation, and Post-Weaning Recovery
Q37709199Neither absence nor excess of FGF23 disturbs murine fetal-placental phosphorus homeostasis or prenatal skeletal development and mineralization.
Q35059741Osteo-renal regulation of systemic phosphate metabolism
Q37231801Parathyroid ultrasonography and bone metabolic profile of patients on dialysis with hyperparathyroidism
Q35679883Phosphate and Klotho
Q28265843Phosphate homeostasis and its role in bone health
Q42230267Phosphatonins: physiological role and pathological changes
Q37190542Secreted klotho and chronic kidney disease
Q36210285Update on fibroblast growth factor 23 in chronic kidney disease
Q34625168Upregulation of calcitriol during pregnancy and skeletal recovery after lactation do not require parathyroid hormone.
Q39812781αKlotho and Chronic Kidney Disease

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