Structural basis by which alternative splicing confers specificity in fibroblast growth factor receptors

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Structural basis by which alternative splicing confers specificity in fibroblast growth factor receptors is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2003PNAS..100.2266Y
P356DOI10.1073/PNAS.0436500100
P8608Fatcat IDrelease_faym2xv3vnf53hhjjwmdtehoni
P3181OpenCitations bibliographic resource ID3652113
P932PMC publication ID151329
P698PubMed publication ID12591959
P5875ResearchGate publication ID10895664

P50authorMoosa MohammadiQ37382162
P2093author name stringAlexander N Plotnikov
Anna V Eliseenkova
Brian K Yeh
Dina Ron
Ifat Sher
Makoto Igarashi
Stuart A Aaronson
P2860cites workStructural basis for FGF receptor dimerization and activationQ22010544
Structural interactions of fibroblast growth factor receptor with its ligandsQ22011005
Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificityQ22254157
Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerizationQ24290400
Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparinQ24290496
Identification of a novel fibroblast growth factor, FGF-22, preferentially expressed in the inner root sheath of the hair follicleQ24291210
Structural basis for fibroblast growth factor receptor 2 activation in Apert syndromeQ24291302
Determination of ligand-binding specificity by alternative splicing: two distinct growth factor receptors encoded by a single geneQ24324199
Exon Switching and Activation of Stromal and Embryonic Fibroblast Growth Factor (FGF)-FGF Receptor Genes in Prostate Epithelial Cells Accompany Stromal Independence and MalignancyQ24602640
Improved methods for building protein models in electron density maps and the location of errors in these modelsQ26776980
Crystallography & NMR System: A New Software Suite for Macromolecular Structure DeterminationQ26778405
MOLSCRIPT: a program to produce both detailed and schematic plots of protein structuresQ26778412
Processing of X-ray diffraction data collected in oscillation modeQ26778468
Structural Basis for Interaction of FGF-1, FGF-2, and FGF-7 with Different Heparan Sulfate Motifs,Q27636426
Cell signaling by receptor tyrosine kinasesQ27860474
Raster3D: photorealistic molecular graphicsQ27860557
Selenomethionyl proteins produced for analysis by multiwavelength anomalous diffraction (MAD): a vehicle for direct determination of three-dimensional structureQ27860618
Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbonsQ27861091
Developmental localization of the splicing alternatives of fibroblast growth factor receptor-2 (FGFR2)Q28263694
Structural and functional diversity in the FGF receptor multigene familyQ28265126
Characterization of Recombinant Human Fibroblast Growth Factor (FGF)-10 Reveals Functional Similarities with Keratinocyte Growth Factor (FGF-7)Q28270502
Chimeric molecules between keratinocyte growth factor and basic fibroblast growth factor define domains that confer receptor binding specificitiesQ28271229
The roles of FGFs in the early development of vertebrate limbsQ28273288
Keratinocyte growth factor is required for hair development but not for wound healingQ28273588
Fgf10 is essential for limb and lung formationQ28295033
Fibroblast growth factor receptor 4 is a high affinity receptor for both acidic and basic fibroblast growth factor but not for keratinocyte growth factorQ28297796
Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb inductionQ28513556
Fgf-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branchlessQ28589182
Apert syndrome mutations in fibroblast growth factor receptor 2 exhibit increased affinity for FGF ligandQ28609661
Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptorQ29616189
AMoRe: an automated package for molecular replacementQ29642803
Correlation between the 1.6 A crystal structure and mutational analysis of keratinocyte growth factorQ30175835
Fibroblast growth factor (FGF) receptor 1-IIIb is a naturally occurring functional receptor for FGFs that is preferentially expressed in the skin and the brainQ30872713
Recent developments in the immunology of inflammatory bowel diseaseQ33815932
FGFs, heparan sulfate and FGFRs: complex interactions essential for developmentQ33828280
Co-transcriptional splicing of pre-messenger RNAs: considerations for the mechanism of alternative splicingQ34402084
Altered expression of keratinocyte growth factor and its receptor in psoriasisQ35764890
Loss of fibroblast growth factor receptor 2 ligand-binding specificity in Apert syndrome.Q35848621
Overexpression of keratinocyte growth factor in cancer cells and enterochromaffin cells in human colorectal cancerQ38311481
Multiple structural elements determine ligand binding of fibroblast growth factor receptors. Evidence that both Ig domain 2 and 3 define receptor specificityQ38320180
Expression of biologically active recombinant keratinocyte growth factor. Structure/function analysis of amino-terminal truncation mutants.Q38321840
Fibroblast growth factor-10. A second candidate stromal to epithelial cell andromedin in prostateQ38325648
Identification of residues important both for primary receptor binding and specificity in fibroblast growth factor-7.Q40860252
Tumour suppressive properties of fibroblast growth factor receptor 2-IIIb in human bladder cancerQ40911311
Regulation by heparan sulfate in fibroblast growth factor signalingQ41505290
A keratinocyte growth factor receptor-derived peptide antagonist identifies part of the ligand binding site.Q41554325
Developmental expression of splicing variants of fibroblast growth factor receptor 3 (FGFR3) in mouse.Q48836850
An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis.Q52171813
Structural and Functional Diversity in the FGf Receptor Multigene FamilyQ55919452
Molecular modeling based mutagenesis defines ligand binding and specificity determining regions of fibroblast growth factor receptorsQ71707631
Ligand-specific structural domains in the fibroblast growth factor receptorQ72191030
Keratinocyte Growth Factor: A Unique Player in Epithelial Repair ProcessesQ77354226
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectalternative mRNA splicing, via spliceosomeQ21114084
P304page(s)2266-71
P577publication date2003-03-04
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleStructural basis by which alternative splicing confers specificity in fibroblast growth factor receptors
P478volume100

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