Co-transcriptional splicing of pre-messenger RNAs: considerations for the mechanism of alternative splicing

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Co-transcriptional splicing of pre-messenger RNAs: considerations for the mechanism of alternative splicing is …
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review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S0378-1119(01)00695-3
P698PubMed publication ID11602343

P2093author name stringA L Greenleaf
M A Garcia-Blanco
A C Goldstrohm
P2860cites workInitial sequencing and analysis of the human genomeQ21045365
Oncoprotein TLS interacts with serine-arginine proteins involved in RNA splicingQ22003961
Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription in vitroQ22008559
A novel transcriptional coactivator, p52, functionally interacts with the essential splicing factor ASF/SF2Q22008652
Mediator of Transcriptional RegulationQ22065418
The Sequence of the Human GenomeQ22065842
Functional association of U2 snRNP with the ATP-independent spliceosomal complex EQ22254390
The apoptosis-promoting factor TIA-1 is a regulator of alternative pre-mRNA splicingQ24290594
Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complexQ24311408
The transcriptional repressor ZFM1 interacts with and modulates the ability of EWS to activate transcriptionQ24313686
A nuclear cap-binding complex binds Balbiani ring pre-mRNA cotranscriptionally and accompanies the ribonucleoprotein particle during nuclear exportQ24322859
EWS, but not EWS-FLI-1, is associated with both TFIID and RNA polymerase II: interactions between two members of the TET family, EWS and hTAFII68, and subunits of TFIID and RNA polymerase II complexes.Q24522406
CUS2, a yeast homolog of human Tat-SF1, rescues function of misfolded U2 through an unusual RNA recognition motifQ24522636
SAF-B protein couples transcription and pre-mRNA splicing to SAR/MAR elementsQ24548190
TLS-ERG leukemia fusion protein inhibits RNA splicing mediated by serine-arginine proteinsQ24554236
Transcriptional cofactor CA150 regulates RNA polymerase II elongation in a TATA-box-dependent mannerQ24554483
hnRNP H is a component of a splicing enhancer complex that activates a c-src alternative exon in neuronal cellsQ24554786
The HIV-1 Tat cellular coactivator Tat-SF1 is a general transcription elongation factorQ24596637
The spliceosome assembly pathway in mammalian extractsQ24601223
Three functional classes of transcriptional activation domainQ24649917
WW domain-mediated interactions reveal a spliceosome-associated protein that binds a third class of proline-rich motif: the proline glycine and methionine-rich motifQ24657609
Protein-interaction modules that organize nuclear function: FF domains of CA150 bind the phosphoCTD of RNA polymerase IIQ24672654
The splicing factor BBP interacts specifically with the pre-mRNA branchpoint sequence UACUAAC.Q27934071
Modulation of RNA polymerase II elongation efficiency by C-terminal heptapeptide repeat domain kinase I.Q27934205
Cross-intron bridging interactions in the yeast commitment complex are conserved in mammalsQ27936705
Transcriptional activation domains stimulate initiation and elongation at different times and via different residuesQ41810274
Coupled in vitro synthesis and splicing of RNA polymerase II transcriptsQ42040067
Capping of eucaryotic mRNAsQ44537736
Both subunits of U2AF recognize the 3' splice site in Caenorhabditis elegansQ47069458
mRNA-type introns in U6 small nuclear RNA genes: implications for the catalysis in pre-mRNA splicingQ48222905
Mutually exclusive splicing of alpha-tropomyosin exons enforced by an unusual lariat branch point location: implications for constitutive splicingQ48302007
Transcriptional elongation by RNA polymerase II is stimulated by transactivators.Q49101405
The splicing factor, Prp40, binds the phosphorylated carboxyl-terminal domain of RNA polymerase II.Q51075771
RNP particles at splice junction sequences on Drosophila chorion transcripts.Q52466521
Splicing of Balbiani ring 1 gene pre-mRNA occurs simultaneously with transcription.Q52544550
A nuclear cap-binding complex facilitates association of U1 snRNP with the cap-proximal 5' splice site.Q55066526
Characteristics of genomic breakpoints in TLS-CHOP translocations in liposarcomas suggest the involvement of Translin and topoisomerase II in the process of translocationQ57033225
What If There Are Only 30,000 Human Genes?Q57986035
Diffusion mechanisms in metallic supercooled liquids and glassesQ59058749
Localization of pre-mRNA splicing in mammalian nucleiQ59083697
In vivo evidence that transcription and splicing are coordinated by a recruiting mechanismQ64377799
U1 snRNP targets an essential splicing factor, U2AF65, to the 3' splice site by a network of interactions spanning the exonQ67469400
In vitro polyadenylation is stimulated by the presence of an upstream intronQ67676618
Positive patches and negative noodles: linking RNA processing to transcription?Q70716691
Human beta-globin pre-mRNA synthesized in vitro is accurately spliced in Xenopus oocyte nucleiQ70821733
The addition of 5' cap structures occurs early in hnRNA synthesis and prematurely terminated molecules are cappedQ71140403
Alternative splicing of fibroblast growth factor receptor 2 (FGF-R2) in human prostate cancerQ74098948
EWS.Fli-1 fusion protein interacts with hyperphosphorylated RNA polymerase II and interferes with serine-arginine protein-mediated RNA splicingQ74303777
The cellular organization of gene expressionQ74701351
RNA polymerase II targets pre-mRNA splicing factors to transcription sites in vivoQ77962891
A yeast intronic splicing enhancer and Nam8p are required for Mer1p-activated splicing.Q27939445
Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcriptionQ28131686
Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1Q28138472
Transcription of eukaryotic protein-coding genesQ28138540
Identification of an RNA binding specificity for the potential splicing factor TLSQ28138875
The splicing factor U1C represses EWS/FLI-mediated transactivationQ28145198
Pre-mRNA splicing: the discovery of a new spliceosome doubles the challengeQ28238029
Protein-protein interactions and 5'-splice-site recognition in mammalian mRNA precursorsQ28251112
Specific interactions between proteins implicated in splice site selection and regulated alternative splicingQ28257351
The transcription factor Spi-1/PU.1 interacts with the potential splicing factor TLSQ28262912
The general transcription factors of RNA polymerase IIQ28298663
The C-terminal domain of RNA polymerase II couples mRNA processing to transcriptionQ28301744
A nuclear matrix protein interacts with the phosphorylated C-terminal domain of RNA polymerase II.Q28509334
The C-terminal domain of the largest subunit of RNA polymerase II interacts with a novel set of serine/arginine-rich proteinsQ28570708
The RNA-binding protein TIA-1 is a novel mammalian splicing regulator acting through intron sequences adjacent to a 5' splice siteQ28609616
An intronic splicing silencer causes skipping of the IIIb exon of fibroblast growth factor receptor 2 through involvement of polypyrimidine tract binding proteinQ28609617
Multiple interdependent sequence elements control splicing of a fibroblast growth factor receptor 2 alternative exonQ28609655
hnRNP A1 recruited to an exon in vivo can function as an exon splicing silencerQ28609663
5'-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase IIQ28623635
Control of elongation by RNA polymerase IIQ28646668
Dynamic association of capping enzymes with transcribing RNA polymerase IIQ29614771
Exon recognition in vertebrate splicingQ29615088
SR proteins and splicing controlQ29619936
P-TEFb, a cyclin-dependent kinase controlling elongation by RNA polymerase IIQ29620167
Regulation of alternative splicing in vivo by overexpression of antagonistic splicing factorsQ29620283
The structure and function of proteins involved in mammalian pre-mRNA splicingQ29620286
The RNA polymerase II holoenzyme and its implications for gene regulationQ29622942
Splice site selection, rate of splicing, and alternative splicing on nascent transcriptsQ30461752
Polypyrimidine tract binding protein antagonizes exon definitionQ33558440
mRNA polyadenylation and its coupling to other RNA processing reactions and to transcriptionQ33680787
Coupling RNA polymerase II transcription with pre-mRNA processingQ33680813
Mechanism and regulation of transcriptional elongation by RNA polymerase II.Q33680820
HIV-1 Tat: coping with negative elongation factorsQ33711447
Exonic splicing enhancers: mechanism of action, diversity and role in human genetic diseasesQ33850031
Transcription elongation factor SII.Q33866716
Huntingtin's WW domain partners in Huntington's disease post-mortem brain fulfill genetic criteria for direct involvement in Huntington's disease pathogenesisQ33915109
The ends of the affair: capping and polyadenylation.Q33920085
Connecting transcription to messenger RNA processingQ33934155
Transcription elongation and human diseaseQ33953565
Protein diversity from alternative splicing: a challenge for bioinformatics and post-genome biologyQ34084341
Quality control of mRNA functionQ34156109
Preferential excision of the 5' proximal intron from mRNA precursors with two introns as mediated by the cap structureQ34332907
The KH domain of the branchpoint sequence binding protein determines specificity for the pre-mRNA branchpoint sequenceQ34361494
The exon sequence TAGG can inhibit splicingQ34597789
The nuclear matrix phosphoprotein p255 associates with splicing complexes as part of the [U4/Y6.U5]tri-snRNP particleQ34767752
Phosphorylated RNA polymerase II stimulates pre-mRNA splicingQ35197241
Intron-dependent recruitment of pre-mRNA splicing factors to sites of transcriptionQ36236894
A functional interaction between the carboxy-terminal domain of RNA polymerase II and pre-mRNA splicingQ36254478
Exon and Intron Sequences, Respectively, Repress and Activate Splicing of a Fibroblast Growth Factor Receptor 2 Alternative ExonQ36554345
Conserved intron elements repress splicing of a neuron-specific c-src exon in vitroQ36555950
Functional association between promoter structure and transcript alternative splicing.Q36597450
Control of BEK and K-SAM splice sites in alternative splicing of the fibroblast growth factor receptor 2 pre-mRNA.Q36699418
Exon definition may facilitate splice site selection in RNAs with multiple exonsQ36713104
Inhibition by SR proteins of splicing of a regulated adenovirus pre-mRNA.Q36799268
Transcription of herpes simplex virus tk sequences under the control of wild-type and mutant human RNA polymerase I promotersQ36885592
Specificity of RNA maturation pathways: RNAs transcribed by RNA polymerase III are not substrates for splicing or polyadenylationQ36922600
Splicing of adenovirus RNA in a cell-free transcription systemQ37347164
Coupling of transcription with alternative splicing: RNA pol II promoters modulate SF2/ASF and 9G8 effects on an exonic splicing enhancerQ38320513
Participation of the C-terminal domain of RNA polymerase II in exon definition during pre-mRNA splicingQ38499037
Evidence for substrate-specific requirement of the splicing factor U2AF(35) and for its function after polypyrimidine tract recognition by U2AF(65).Q39449313
An intronic sequence element mediates both activation and repression of rat fibroblast growth factor receptor 2 pre-mRNA splicingQ39631167
The 5' and 3' splice sites come together via a three dimensional diffusion mechanismQ39716206
Common themes in assembly and function of eukaryotic transcription complexesQ40422045
Regulation of transcriptional elongation by RNA polymerase II.Q40445607
Role of RNA polymerase II carboxy-terminal domain in coordinating transcription with RNA processingQ40945481
A novel isoform ratio switch of the polypyrimidine tract binding proteinQ40951842
Reciprocal effects of splicing and polyadenylation on human immunodeficiency virus type 1 pre-mRNA processingQ41158512
RNA polymerase slides home: pause and termination site recognitionQ41444690
A comparison of mammalian and yeast pre-mRNA 3'-end processingQ41477066
Basic mechanisms of transcript elongation and its regulationQ41550178
Transcription units as RNA processing unitsQ41667132
P433issue1-2
P407language of work or nameEnglishQ1860
P921main subjectalternative mRNA splicing, via spliceosomeQ21114084
P304page(s)31-47
P577publication date2001-10-01
P1433published inGeneQ5531065
P1476titleCo-transcriptional splicing of pre-messenger RNAs: considerations for the mechanism of alternative splicing
P478volume277

Reverse relations

cites work (P2860)
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