| scholarly article | Q13442814 |
| P356 | DOI | 10.1101/GAD.4.9.1552 |
| P953 | full work available at URL | https://syndication.highwire.org/content/doi/10.1101/gad.4.9.1552 |
| P698 | PubMed publication ID | 1701407 |
| P2093 | author name string | S. M. Berget | |
| M. Niwa | |||
| S. D. Rose | |||
| P2860 | cites work | Splice site selection, rate of splicing, and alternative splicing on nascent transcripts | Q30461752 |
| Steps in the processing of Ad2 mRNA: poly(A)+ nuclear sequences are conserved and poly(A) addition precedes splicing | Q34057240 | ||
| Hydroxyl radical "footprinting" of RNA: application to pre-mRNA splicing complexes | Q34311067 | ||
| A survey on intron and exon lengths | Q39542729 | ||
| Intervening sequences increase efficiency of RNA 3' processing and accumulation of cytoplasmic RNA | Q40514288 | ||
| Introns in histone genes alter the distribution of 3' ends | Q40517116 | ||
| In vitro cleavage of the simian virus 40 early polyadenylation site adjacent to a required downstream TG sequence | Q40668071 | ||
| 3' cleavage and polyadenylation of mRNA precursors in vitro requires a poly(A) polymerase, a cleavage factor, and a snRNP | Q64379456 | ||
| Structure of late adenovirus 2 heterogeneous nuclear RNA | Q64382107 | ||
| Definition of an efficient synthetic poly(A) site | Q69373727 | ||
| Sequence requirements for splicing of higher eukaryotic nuclear pre-mRNA | Q69660486 | ||
| A mutational analysis of spliceosome assembly: evidence for splice site collaboration during spliceosome formation | Q69811708 | ||
| Separation and characterization of a poly(A) polymerase and a cleavage/specificity factor required for pre-mRNA polyadenylation | Q69820089 | ||
| P433 | issue | 9 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | genetics | Q7162 |
| P304 | page(s) | 1552-1559 | |
| P577 | publication date | 1990-09-01 | |
| P1433 | published in | Genes & Development | Q1524533 |
| P1476 | title | In vitro polyadenylation is stimulated by the presence of an upstream intron | |
| P478 | volume | 4 |
| Q39717702 | 3' Processing and termination of mouse histone transcripts synthesized in vitro by RNA polymerase II. |
| Q24648650 | 3' end mRNA processing: molecular mechanisms and implications for health and disease |
| Q34365389 | 5' exon replacement and repair by spliceosome-mediated RNA trans-splicing |
| Q35081547 | A complex containing CstF-64 and the SL2 snRNP connects mRNA 3' end formation and trans-splicing in C. elegans operons. |
| Q42634656 | A complex gene regulatory mechanism that operates at the nexus of multiple RNA processing decisions |
| Q27939993 | A link between secretion and pre-mRNA processing defects in Saccharomyces cerevisiae and the identification of a novel splicing gene, RSE1 |
| Q36883864 | A mini-intronic plasmid (MIP): a novel robust transgene expression vector in vivo and in vitro |
| Q71972218 | A near-upstream element in a plant polyadenylation signal consists of more than six nucleotides |
| Q41837652 | A novel function for the U2AF 65 splicing factor in promoting pre-mRNA 3'-end processing. |
| Q36226779 | A novel gene expression system: non-viral gene transfer for hemophilia as model systems |
| Q34660002 | A simple model to explain evolutionary trends of eukaryotic gene architecture and expression: how competition between splicing and cleavage/polyadenylation factors may affect gene expression and splice-site recognition in eukaryotes |
| Q33987552 | A splicing enhancer in the E4 coding region of human papillomavirus type 16 is required for early mRNA splicing and polyadenylation as well as inhibition of premature late gene expression |
| Q33964251 | Aberrant splicing and transcription termination caused by P element insertion into the intron of a Drosophila gene |
| Q91565524 | Alternative cleavage and polyadenylation in health and disease |
| Q26864222 | Alternative cleavage and polyadenylation: the long and short of it |
| Q36382872 | Alternative exon definition events control the choice between nuclear retention and cytoplasmic export of U11/U12-65K mRNA. |
| Q34630891 | Alternative poly(A) site selection in complex transcription units: means to an end? |
| Q33832891 | Alternative polyadenylation of mRNA precursors. |
| Q40641554 | An RNA-binding protein specifically interacts with a functionally important domain of the downstream element of the simian virus 40 late polyadenylation signal |
| Q28204111 | An evolutionarily conserved role for SRm160 in 3'-end processing that functions independently of exon junction complex formation |
| Q24306150 | An interaction between U2AF 65 and CF I(m) links the splicing and 3' end processing machineries |
| Q44514700 | An intron is required for dihydrofolate reductase protein stability |
| Q73485680 | Analysis of regulatory elements of the promoter and the 3' untranslated region of the maize Hrgp gene coding for a cell wall protein |
| Q43805887 | Analysis of the polyadenylation consensus sequence context in the genes of nuclear encoded mitochondrial proteins |
| Q40654122 | Analysis of the stimulatory effect of splicing on mRNA production and utilization in mammalian cells |
| Q21263194 | Arabidopsis mRNA polyadenylation machinery: comprehensive analysis of protein-protein interactions and gene expression profiling |
| Q59098666 | Are vertebrate exons scanned during splice-site selection? |
| Q24297890 | Association of polyadenylation cleavage factor I with U1 snRNP |
| Q39595460 | Association with the cellular export receptor CRM 1 mediates function and intracellular localization of Epstein-Barr virus SM protein, a regulator of gene expression. |
| Q33925172 | Binding of hnRNP L to the pre-mRNA processing enhancer of the herpes simplex virus thymidine kinase gene enhances both polyadenylation and nucleocytoplasmic export of intronless mRNAs |
| Q41062668 | Biochemical analysis of TREX complex recruitment to intronless and intron-containing yeast genes |
| Q39218711 | CTD serine-2 plays a critical role in splicing and termination factor recruitment to RNA polymerase II in vivo |
| Q24601077 | Capping, splicing, and 3' processing are independently stimulated by RNA polymerase II: different functions for different segments of the CTD |
| Q34282553 | Characterization of specific protein-RNA complexes associated with the coupling of polyadenylation and last-intron removal |
| Q39269835 | Cleavage and polyadenylation: Ending the message expands gene regulation |
| Q34402084 | Co-transcriptional splicing of pre-messenger RNAs: considerations for the mechanism of alternative splicing |
| Q41870191 | Competition within Introns: Splicing Wins over Polyadenylation via a General Mechanism |
| Q28202505 | Coordination between transcription and pre-mRNA processing |
| Q37130394 | Coupling between alternative polyadenylation and alternative splicing is limited to terminal introns |
| Q35006630 | Coupling mRNA processing with transcription in time and space. |
| Q24294619 | Distinct sequence motifs within the 68-kDa subunit of cleavage factor Im mediate RNA binding, protein-protein interactions, and subcellular localization |
| Q33827197 | Downstream sequence elements with different affinities for the hnRNP H/H' protein influence the processing efficiency of mammalian polyadenylation signals |
| Q39722819 | Efficient 3'-end formation of human beta-globin mRNA in vivo requires sequences within the last intron but occurs independently of the splicing reaction |
| Q33559663 | Efficient polyadenylation of Rous sarcoma virus RNA requires the negative regulator of splicing element |
| Q35020287 | Efficient selection of 3'-terminal exons from vertebrate DNA. |
| Q38748176 | Evidence that a threshold of serine/arginine-rich (SR) proteins recruits CFIm to promote rous sarcoma virus mRNA 3' end formation |
| Q36173074 | Exclusion of RPGRIP1 ins44 from primary causal association with early-onset cone-rod dystrophy in dogs. |
| Q36160767 | Exon junction complexes mediate the enhancing effect of splicing on mRNA expression |
| Q36642718 | Exon size affects competition between splicing and cleavage-polyadenylation in the immunoglobulin mu gene |
| Q36237129 | Forced expression of dystrophin deletion constructs reveals structure-function correlations. |
| Q28609911 | Formation of mRNA 3' ends in eukaryotes: mechanism, regulation, and interrelationships with other steps in mRNA synthesis |
| Q41911100 | Functional coupling of last-intron splicing and 3'-end processing to transcription in vitro: the poly(A) signal couples to splicing before committing to cleavage |
| Q24798227 | Gene trap mutagenesis of hnRNP A2/B1: a cryptic 3' splice site in the neomycin resistance gene allows continued expression of the disrupted cellular gene |
| Q33800574 | Herpes simplex virus ICP27 induces cytoplasmic accumulation of unspliced polyadenylated alpha-globin pre-mRNA in infected HeLa cells. |
| Q33838515 | Heterogeneity in mammalian RNA 3' end formation |
| Q45868873 | High-Level Factor VIII Gene ExpressionIn VivoAchieved by Nonviral Liver-Specific Gene Therapy Vectors |
| Q37080336 | Human TREX component Thoc5 affects alternative polyadenylation site choice by recruiting mammalian cleavage factor I. |
| Q64383011 | Human adenovirus type 5 variants with sequence alterations flanking the E2A gene: effects on E2 expression and DNA replication |
| Q39870230 | Human papillomavirus type 31b late gene expression is regulated through protein kinase C-mediated changes in RNA processing. |
| Q40397361 | Hypomorphic mutation in hnRNP U results in post-implantation lethality |
| Q34361445 | Identification of two cis-acting elements that independently regulate the length of poly(A) on Xenopus albumin pre-mRNA. |
| Q42615597 | Improperly terminated, unpolyadenylated mRNA of sense transgenes is targeted by RDR6-mediated RNA silencing in Arabidopsis. |
| Q47133300 | Independence between pre-mRNA splicing and DNA methylation in an isogenic minigene resource |
| Q57093797 | Influenza virus infection causes global RNAPII termination defects |
| Q33567881 | Inhibition of U4 snRNA in human cells causes the stable retention of polyadenylated pre-mRNA in the nucleus |
| Q41719752 | Intron-mediated enhancement of gene expression independent of unique intron sequences and splicing |
| Q33890618 | Intronless mRNA transport elements may affect multiple steps of pre-mRNA processing |
| Q36675830 | Introns are essential for growth-regulated expression of the mouse thymidylate synthase gene |
| Q35363252 | Juxtaposition of two distant, serine-arginine-rich protein-binding elements is required for optimal polyadenylation in Rous sarcoma virus |
| Q34411315 | Kinetic competition during the transcription cycle results in stochastic RNA processing |
| Q36567171 | Lack of an effect of the efficiency of RNA 3'-end formation on the efficiency of removal of either the final or the penultimate intron in intact cells |
| Q52539732 | Length increase of the human alpha -globin 3'-untranslated region disrupts stability of the pre-mRNA but not that of the mature mRNA. |
| Q33652430 | Low-Dose Gene Therapy for Murine PKU Using Episomal Naked DNA Vectors Expressing PAH from Its Endogenous Liver Promoter |
| Q36818995 | Mechanisms controlling production of membrane and secreted immunoglobulin during B cell development |
| Q45761998 | Message ends: RNA 3' processing and flowering time control |
| Q91644977 | Multifunctional Alleles: A novel method for the generation of "All-In-One" null and conditional alleles |
| Q62712510 | Mutations that alter RNA splicing of the human HPRT gene: a review of the spectrum |
| Q36425890 | Non-viral therapeutic approaches to ocular diseases: An overview and future directions |
| Q36697079 | Nucleotide 880 splice donor site required for efficient transformation and RNA accumulation by human papillomavirus type 16 E7 gene |
| Q45878786 | Optimization of transcriptional regulatory elements for constructing plasmid vectors |
| Q40506141 | Organization of (pre-)mRNA metabolism in the cell nucleus |
| Q39539788 | Overexpression of essential splicing factor ASF/SF2 blocks the temporal shift in adenovirus pre-mRNA splicing and reduces virus progeny formation |
| Q21245196 | Overlapping enhancer/promoter and transcriptional termination signals in the lentiviral long terminal repeat |
| Q34315689 | Pararetroviruses and retroviruses: a comparative review of viral structure and gene expression strategies. |
| Q38499037 | Participation of the C-terminal domain of RNA polymerase II in exon definition during pre-mRNA splicing |
| Q24320261 | Participation of the nuclear cap binding complex in pre-mRNA 3' processing |
| Q36669203 | Physical Isolation of Nascent RNA Chains Transcribed by RNA Polymerase II: Evidence for Cotranscriptional Splicing |
| Q38884107 | Poly(A) Polymerase and the Nuclear Poly(A) Binding Protein, PABPN1, Coordinate the Splicing and Degradation of a Subset of Human Pre-mRNAs. |
| Q39631274 | Poly(A)-driven and poly(A)-assisted termination: two different modes of poly(A)-dependent transcription termination |
| Q54981229 | Polyadenylation precedes splicing in vitro |
| Q37168944 | Polyadenylation releases mRNA from RNA polymerase II in a process that is licensed by splicing |
| Q35020503 | Polyadenylation site selection cannot occur in vivo after excision of the 3'-terminal intron |
| Q37474288 | Polyadenylylation in copia requires unusually distant upstream sequences |
| Q40815645 | Polypyrimidine tract binding protein modulates efficiency of polyadenylation. |
| Q34362387 | Position-dependent inhibition of the cleavage step of pre-mRNA 3'-end processing by U1 snRNP |
| Q36817062 | Posttranscriptional regulation of rat growth hormone gene expression: increased message stability and nuclear polyadenylation accompany thyroid hormone depletion |
| Q37693565 | Pre-mRNA 3'-end processing complex assembly and function |
| Q24805800 | Pre-mRNA processing enhancer (PPE) elements from intronless genes play additional roles in mRNA biogenesis than do ones from intron-containing genes |
| Q26746120 | Processing and transcriptome expansion at the mRNA 3' end in health and disease: finding the right end |
| Q33809422 | Processing of alpha-globin and ICP0 mRNA in cells infected with herpes simplex virus type 1 ICP27 mutants |
| Q39642143 | Production and characterization of improved adenovirus vectors with the E1, E2b, and E3 genes deleted |
| Q39864399 | Promoter proximal splice sites enhance transcription |
| Q28221126 | RNA polymerase II conducts a symphony of pre-mRNA processing activities |
| Q29614773 | RNA polymerase II is an essential mRNA polyadenylation factor |
| Q36955546 | RNA processing control in avian retroviruses |
| Q36562192 | RNA structure is a critical determinant of poly(A) site recognition by cleavage and polyadenylation specificity factor |
| Q34546187 | RNA-protein interactions that regulate pre-mRNA splicing. |
| Q40309178 | Regulated adenovirus mRNA 3'-end formation in a coupled in vitro transcription-processing system |
| Q39575715 | Regulation of alternative polyadenylation by U1 snRNPs and SRp20. |
| Q40508994 | Regulation of polyadenylation in hepatitis B viruses: stimulation by the upstream activating signal PS1 is orientation-dependent, distance-independent, and additive |
| Q41592106 | Relative roles of signals upstream of AAUAAA and promoter proximity in regulation of human immunodeficiency virus type 1 mRNA 3' end formation |
| Q36438303 | Requirements for enhanced transgene expression by untranslated sequences from the human cytomegalovirus immediate-early gene |
| Q73487191 | Retrotransposon insertion into the maize waxy gene results in tissue-specific RNA processing |
| Q24538266 | SRm160 splicing coactivator promotes transcript 3'-end cleavage |
| Q53004821 | SV40 T1-mRNA trans-splicing and translation requires that the in vitro synthesized cRNA is capped before microinjection. |
| Q43182198 | Sequence and spatial requirements for the tissue- and species-independent 3'-end processing mechanism of plant mRNA. |
| Q34595058 | Sequence of the polypyrimidine tract of the 3'-terminal 3' splicing signal can affect intron-dependent pre-mRNA processing in vivo |
| Q36685614 | Sequences Within the Last Intron function in RNA 3'-End Formation in Cultured Cells |
| Q36663019 | Sequences homologous to 5' splice sites are required for the inhibitory activity of papillomavirus late 3' untranslated regions |
| Q40642300 | Sequences regulating temporal poly(A) site switching in the adenovirus major late transcription unit |
| Q36099207 | Serine/arginine-rich proteins contribute to negative regulator of splicing element-stimulated polyadenylation in rous sarcoma virus |
| Q41683806 | Sex-specific splicing and polyadenylation of dsx pre-mRNA requires a sequence that binds specifically to tra-2 protein in vitro |
| Q35802980 | Silent point mutation in an avian retrovirus RNA processing element promotes c-myb-associated short-latency lymphomas |
| Q36828243 | Simian virus 40 late mRNA leader sequences involved in augmenting mRNA accumulation via multiple mechanisms, including increased polyadenylation efficiency |
| Q37131633 | Small molecule activators of pre-mRNA 3' cleavage |
| Q36738496 | Splice site choice in a complex transcription unit containing multiple inefficient polyadenylation signals |
| Q36828187 | Splice site skipping in polyomavirus late pre-mRNA processing |
| Q39479568 | Spliceosome assembly is coupled to RNA polymerase II dynamics at the 3' end of human genes |
| Q24489623 | Splicing factors stimulate polyadenylation via USEs at non-canonical 3' end formation signals |
| Q41288678 | Splicing of precursors to mRNA in higher plants: mechanism, regulation and sub-nuclear organisation of the spliceosomal machinery |
| Q36491243 | Splicing promotes rapid and efficient mRNA export in mammalian cells |
| Q41824813 | Splicing-coupled 3' end formation requires a terminal splice acceptor site, but not intron excision |
| Q39589633 | Split-intron retroviral vectors: enhanced expression with improved safety |
| Q35015587 | Stimulation of gene expression by introns: conversion of an inhibitory intron to a stimulatory intron by alteration of the splice donor sequence |
| Q40734146 | Strength evaluation of transcriptional regulatory elements for transgene expression by adenovirus vector |
| Q33601680 | Structurally diverse low molecular weight activators of the mammalian pre-mRNA 3' cleavage reaction |
| Q35532398 | Systematic profiling of poly(A)+ transcripts modulated by core 3' end processing and splicing factors reveals regulatory rules of alternative cleavage and polyadenylation |
| Q21131971 | Tandem RNA chimeras contribute to transcriptome diversity in human population and are associated with intronic genetic variants |
| Q38297247 | Temporal Dissection of Rate Limiting Transcriptional Events Using Pol II ChIP and RNA Analysis of Adrenergic Stress Gene Activation. |
| Q77308193 | Terminal exon definition occurs cotranscriptionally and promotes termination of RNA polymerase II |
| Q27863699 | The 3'-end-processing factor CPSF is required for the splicing of single-intron pre-mRNAs in vivo |
| Q28301744 | The C-terminal domain of RNA polymerase II couples mRNA processing to transcription |
| Q36224577 | The Epstein-Barr virus nuclear protein SM is both a post-transcriptional inhibitor and activator of gene expression |
| Q42122438 | The HIV-1 5' LTR poly(A) site is inactivated by U1 snRNP interaction with the downstream major splice donor site. |
| Q34280639 | The adeno-associated virus type 2 Rep protein regulates RNA processing via interaction with the transcription template |
| Q36559866 | The cap and the 3' splice site similarly affect polyadenylation efficiency |
| Q40442143 | The carboxyl terminus of vertebrate poly(A) polymerase interacts with U2AF 65 to couple 3'-end processing and splicing |
| Q28140003 | The gene for a variant form of the polyadenylation protein CstF-64 is on chromosome 19 and is expressed in pachytene spermatocytes in mice |
| Q36551242 | The human immunodeficiency virus type 1 Rev protein and the Rev-responsive element counteract the effect of an inhibitory 5' splice site in a 3' untranslated region |
| Q36963581 | The low-abundance U11 and U12 small nuclear ribonucleoproteins (snRNPs) interact to form a two-snRNP complex |
| Q36582266 | The mouse histone H2a gene contains a small element that facilitates cytoplasmic accumulation of intronless gene transcripts and of unspliced HIV-1-related mRNAs |
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| Q35262636 | The presence of multiple introns is essential for ERECTA expression in Arabidopsis |
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