Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

scientific article (publication date: 1991)

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/PROT.340110407
P3181OpenCitations bibliographic resource ID3251677
P698PubMed publication ID1758883
P5875ResearchGate publication ID21396673

P2093author name stringK A Sharp
B Honig
A Nicholls
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectprotein foldingQ847556
P304page(s)281-96
P577publication date1991-01-01
P1433published inProteinsQ7251514
P1476titleProtein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons
P478volume11

Reverse relations

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Q78010351Base substitution specificity of DNA polymerase beta depends on interactions in the DNA minor groove
Q27732644Batimastat, a potent matrix mealloproteinase inhibitor, exhibits an unexpected mode of binding
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Q79137251Binding of TFIIB to RNA polymerase II: Mapping the binding site for the TFIIB zinc ribbon domain within the preinitiation complex
Q27620474Binding of non-catalytic ATP to human hexokinase I highlights the structural components for enzyme-membrane association control
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Q34354149Binding-linked protonation of a DNA minor-groove agent
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Q44171115Biochemical and functional analysis of smallpox growth factor (SPGF) and anti-SPGF monoclonal antibodies.
Q33265872Biochemical and structural domain analysis of xeroderma pigmentosum complementation group C protein
Q33780632Biochemical characterization of rous sarcoma virus MA protein interaction with membranes
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Q27748803Biological identity and diversity in photosynthesis and respiration: structure of the lumen-side domain of the chloroplast Rieske protein
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Q27737259Bombyx mori single repeat telomeric DNA sequence forms a G-quadruplex capped by base triads
Q56346668Bouganin, an Attractive Weapon for Immunotoxins
Q27732687Bound water structure and polymorphic amino acids act together to allow the binding of different peptides to MHC class I HLA-B53
Q27480836Bovine viral diarrhea virus NS3 serine proteinase: polyprotein cleavage sites, cofactor requirements, and molecular model of an enzyme essential for pestivirus replication
Q27734277Brain acetylhydrolase that inactivates platelet-activating factor is a G-protein-like trimer
Q53615845Branchio-oto-renal syndrome associated mutations in Eyes Absent 1 result in loss of phosphatase activity.
Q24537432Brownian dynamics simulations of interaction between scorpion toxin Lq2 and potassium ion channel.
Q74250956Brownian dynamics simulations of the recognition of the scorpion toxin P05 with the small-conductance calcium-activated potassium channels
Q34179045Brownian dynamics simulations of the recognition of the scorpion toxin maurotoxin with the voltage-gated potassium ion channels
Q34169503Brownian dynamics study of the interaction between plastocyanin and cytochrome f
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Q27639391Carbamoyl-phosphate synthetase. Creation of an escape route for ammonia
Q27764883Carboxymethyl-phenylalanine as a replacement for phosphotyrosine in SH2 domain binding
Q36582058Cataloging the relationships between proteins: a review of interaction databases
Q44250341Catalysis on the coastline: theozyme, molecular dynamics, and free energy perturbation analysis of antibody 21D8 catalysis of the decarboxylation of 5-nitro-3-carboxybenzisoxazole
Q27640455Catalysis, specificity, and ACP docking site of Streptomyces coelicolor malonyl-CoA:ACP transacylase
Q27628268Catalytic center assembly of HPPK as revealed by the crystal structure of a ternary complex at 1.25 A resolution
Q27655151Catalytic core of a membrane-associated eukaryotic polyphosphate polymerase
Q27641294Catalytic mechanism revealed by the crystal structure of undecaprenyl pyrophosphate synthase in complex with sulfate, magnesium, and triton
Q27636221Catalytic mechanisms and reaction intermediates along the hydrolytic pathway of a plant beta-D-glucan glucohydrolase
Q27627623Change in dimerization mode by removal of a single unsatisfied polar residue located at the interface
Q24671918Channelling and formation of 'active' formaldehyde in dimethylglycine oxidase
Q27639979Chaperone priming of pilus subunits facilitates a topological transition that drives fiber formation
Q28276039Chaperonins
Q28583807Characterization and chromosomal localization of PTP-NP-2, a new isoform of protein tyrosine phosphatase-like receptor, expressed on synaptic boutons
Q41989123Characterization and molecular basis of the oligomeric structure of HIV-1 nef protein
Q35131525Characterization and mutational analysis of omega-class GST (GSTO1) from Apis cerana cerana, a gene involved in response to oxidative stress
Q24301915Characterization of a gamma-adaptin ear-binding motif in enthoprotin
Q48183464Characterization of a novel RP2-OSTF1 interaction and its implication for actin remodeling
Q40900594Characterization of critical interactions between Ndt80 and MSE DNA defining a novel family of Ig-fold transcription factors
Q45902527Characterization of dipeptidylcarboxypeptidase of Leishmania donovani: a molecular model for structure based design of antileishmanials.
Q33843319Characterization of novel cathepsin K mutations in the pro and mature polypeptide regions causing pycnodysostosis.
Q24554585Characterization of the DNA-binding and dimerization properties of the nuclear orphan receptor germ cell nuclear factor
Q36472769Characterization of the fast dynamics of protein amino acid side chains using NMR relaxation in solution
Q33465074Characterization of the wheat endosperm transfer cell-specific protein TaPR60.
Q44277861Charge-charge interactions are key determinants of the pK values of ionizable groups in ribonuclease Sa (pI=3.5) and a basic variant (pI=10.2).
Q44758494Charged residue changes in the carboxy-terminus of alpha-tropomyosin alter mouse cardiac muscle contractility
Q22254620Charged residues dominate a unique interlocking topography in the heterodimeric cytokine interleukin-12
Q77210975Chemical shift as a probe of molecular interfaces: NMR studies of DNA binding by the three amino-terminal zinc finger domains from transcription factor IIIA
Q33247969Chinese-scorpion (Buthus martensi Karsch) toxin BmK alphaIV, a novel modulator of sodium channels: from genomic organization to functional analysis
Q27617857Chloroplast NADP-malate dehydrogenase: structural basis of light-dependent regulation of activity by thiol oxidation and reduction
Q34571971Choline acetyltransferase structure reveals distribution of mutations that cause motor disorders.
Q24674282Chymotryptic specificity determinants in the 1.0 A structure of the zinc-inhibited human tissue kallikrein 7
Q27631018Class I major histocompatibility complex anchor substitutions alter the conformation of T cell receptor contacts
Q47998083Class I molecules with similar peptide-binding specificities are the result of both common ancestry and convergent evolution
Q24672270Clathrin self-assembly involves coordinated weak interactions favorable for cellular regulation
Q27618539Clathrin self-assembly is mediated by a tandemly repeated superhelix
Q47839874Cloning and characterization of a monocot mannose-binding lectin from Crocus vernus (family Iridaceae).
Q35563692Close Encounters of the Transient Kind: Protein Interactions in the Photosynthetic Redox Chain Investigated by NMR Spectroscopy
Q34867355Close identity of a pressure-stabilized intermediate with a kinetic intermediate in protein folding
Q82616680Close membrane-membrane proximity induced by Ca(2+)-dependent multivalent binding of synaptotagmin-1 to phospholipids
Q27639480Closed site complexes of adenine phosphoribosyltransferase from Giardia lamblia reveal a mechanism of ribosyl migration
Q27641809Coactivator binding promotes the specific interaction between ligand and the pregnane X receptor
Q24530587Cobatoxin 1 from Centruroides noxius scorpion venom: chemical synthesis, three-dimensional structure in solution, pharmacology and docking on K+ channels
Q57077250Cocrystal Structures of Diaminopimelate Decarboxylase
Q27739838Cocrystal structure of the messenger RNA 5' cap-binding protein (eIF4E) bound to 7-methyl-GDP
Q34148451Cold adapted enzymes.
Q34550744Collagen-binding I domain integrins--what do they do?
Q39737085Common interaction surfaces of the toll-like receptor 4 cytoplasmic domain stimulate multiple nuclear targets
Q27622761Comparative X-ray analysis of the un-liganded fosfomycin-target murA
Q48546612Comparative analysis of the surface interaction properties of the binding sites of CDK2, CDK4, and ERK2.
Q43979207Comparative modeling of the phosphatase and kinase domains of protein tyrosine phosphatase and insulin receptor kinase from Drosophila melanogaster (DPTP61fm), and a computational study of their mutual interactions.
Q57752842Comparative modeling of the three-dimensional structures of family 3 glycoside hydrolases
Q30429116Comparative protein modeling by satisfaction of spatial restraints
Q43030179Comparative structural analysis of psychrophilic and meso- and thermophilic enzymes
Q27643112Comparing skeletal and cardiac calsequestrin structures and their calcium binding: a proposed mechanism for coupled calcium binding and protein polymerization
Q40293709Comparison of NMR structures and model-membrane interactions of 15-residue antimicrobial peptides derived from bovine lactoferricin
Q39593409Comparison of second-strand transfer requirements and RNase H cleavages catalyzed by human immunodeficiency virus type 1 reverse transcriptase (RT) and E478Q RT.
Q44509252Comparison of the closed conformation of the beta 1,4-galactosyltransferase-1 (beta 4Gal-T1) in the presence and absence of alpha-lactalbumin (LA).
Q36593741Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2.
Q27643002Complement regulation at the molecular level: The structure of decay-accelerating factor
Q27472918Complete predicted three-dimensional structure of the facilitator transmembrane protein and hepatitis C virus receptor CD81: conserved and variable structural domains in the tetraspanin superfamily
Q40612986Completion of trimeric hairpin formation of influenza virus hemagglutinin promotes fusion pore opening and enlargement
Q24291172Complex structure of the activating immunoreceptor NKG2D and its MHC class I-like ligand MICA
Q34806039Comprehensive in silico mutagenesis highlights functionally important residues in proteins
Q36681816Computational analyses of the surface properties of protein-protein interfaces.
Q27647665Computational design and experimental study of tighter binding peptides to an inactivated mutant of HIV-1 protease
Q34116670Computational docking and solution x-ray scattering predict a membrane-interacting role for the histone domain of the Ras activator son of sevenless
Q34185962Computational simulations of interactions of scorpion toxins with the voltage-gated potassium ion channel
Q41585193Computational tools for structure-based ligand design
Q58006839Computer Modeling of the Membrane Interaction of FYVE Domains
Q34187044Conductance studies on trichotoxin_A50E and implications for channel structure
Q73924701Conformation of an Shc-derived phosphotyrosine-containing peptide complexed with the Grb2 SH2 domain
Q27678601Conformational Selection and Folding-upon-binding of Intrinsically Disordered Protein CP12 Regulate Photosynthetic Enzymes Assembly
Q35773629Conformational Transitions and Convergence of Absolute Binding Free Energy Calculations
Q27639743Conformational changes in phosphoglucose isomerase induced by ligand binding
Q27760231Conformational changes on substrate binding to methylmalonyl CoA mutase and new insights into the free radical mechanism
Q27637067Conformational plasticity revealed by the cocrystal structure of NKG2D and its class I MHC-like ligand ULBP3
Q27621935Conformational substates in different crystal forms of the photoactive yellow protein-Correlation with theoretical and experimental flexibility
Q27733590Conformational variability in the refined structure of the chaperonin GroEL at 2.8 A resolution
Q27749635Conformational variability of the N-terminal helix in the structure of ribosomal protein S15
Q39454128Conservation and function of a potential substrate-binding domain in the yeast Clb5 B-type cyclin
Q34098437Conservation and relative importance of residues across protein-protein interfaces
Q47303165Conserved Binding Regions Provide the Clue for Peptide-Based Vaccine Development: A Chemical Perspective.
Q27649358Conserved Themes in Target Recognition by the PAH1 and PAH2 Domains of the Sin3 Transcriptional Corepressor
Q27765281Conserved mode of peptidomimetic inhibition and substrate recognition of human cytomegalovirus protease
Q42404704Conserved residues in the extracellular loops of short-wavelength cone visual pigments
Q33938813Conserved role of a complement-like protein in phagocytosis revealed by dsRNA knockout in cultured cells of the mosquito, Anopheles gambiae.
Q40585986Contingent phosphorylation/dephosphorylation provides a mechanism of molecular memory in WASP.
Q93069536Continuous Wave Electron Paramagnetic Resonance Spectroscopy Reveals the Structural Topology and Dynamic Properties of Active Pinholin S2168 in a Lipid Bilayer
Q30447495Continuum solvent model calculations of alamethicin-membrane interactions: thermodynamic aspects
Q50962286Contortions of encapsulated alkyl groups.
Q28203579Contrasting membrane interaction mechanisms of AP180 N-terminal homology (ANTH) and epsin N-terminal homology (ENTH) domains
Q45134850Contribution of the hydrophobic effect to globular protein stability
Q41897876Contribution of the two conserved tryptophan residues to the catalytic and structural properties of Proteus mirabilis glutathione S-transferase B1-1.
Q43947466Contributions to the binding free energy of ligands to avidin and streptavidin.
Q34989951Copper chaperones
Q27639131Core side-chain packing and backbone conformation in Lpp-56 coiled-coil mutants
Q27736064Core structure of gp41 from the HIV envelope glycoprotein
Q27748834Correction of the NMR structure of the ETS1/DNA complex
Q57973487Covalently crosslinked complexes of bovine adrenodoxin with adrenodoxin reductase and cytochrome P450scc
Q36277916Crevice-forming mutants of bovine pancreatic trypsin inhibitor: stability changes and new hydrophobic surface
Q30194443Critical residues in an SH3 domain from Sem-5 suggest a mechanism for proline-rich peptide recognition
Q28507010Crooked tail (Cd) model of human folate-responsive neural tube defects is mutated in Wnt coreceptor lipoprotein receptor-related protein 6.
Q34519285Cross-talk unfolded: MARCKS proteins
Q27649963Crossreactive T Cells Spotlight the Germline Rules for αβ T Cell-Receptor Interactions with MHC Molecules
Q37697992Crowding induced collective hydration of biological macromolecules over extended distances
Q56452854Crystal Structure and Binding Properties of the CD2 and CD244 (2B4)-binding Protein, CD48
Q27681209Crystal Structure of Arabidopsis Cyclophilin38 Reveals a Previously Uncharacterized Immunophilin Fold and a Possible Autoinhibitory Mechanism
Q27642234Crystal Structure of ClpX Molecular Chaperone from Helicobacter pylori
Q27667381Crystal Structure of Leukocyte Ig-like Receptor LILRB4 (ILT3/LIR-5/CD85k): A MYELOID INHIBITORY RECEPTOR INVOLVED IN IMMUNE TOLERANCE
Q27653576Crystal Structure of Malaria Parasite Nucleosome Assembly Protein: DISTINCT MODES OF PROTEIN LOCALIZATION AND HISTONE RECOGNITION
Q27641060Crystal Structure of Neisserial Surface Protein A (NspA), a Conserved Outer Membrane Protein with Vaccine Potential
Q27642538Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima and Mechanism of Product Chain Length Determination
Q27641031Crystal Structure of Thermostable Aspartase from Bacillus sp. YM55-1: Structure-based Exploration of Functional Sites in the Aspartase Family
Q58868803Crystal Structure of Type-III Geranylgeranyl Pyrophosphate Synthase fromSaccharomyces cerevisiaeand the Mechanism of Product Chain Length Determination
Q27642347Crystal Structure of a Family 4 Uracil-DNA Glycosylase from Thermus thermophilus HB8
Q27488306Crystal Structure of a Novel Dimeric Form of NS5A Domain I Protein from Hepatitis C Virus
Q56338185Crystal Structure of a Phosphorylated Smad2
Q27641583Crystal Structure of a Putative Methyltransferase from Mycobacterium tuberculosis: Misannotation of a Genome Clarified by Protein Structural Analysis
Q27641238Crystal Structure of the Avilamycin Resistance-conferring Methyltransferase AviRa from Streptomyces viridochromogenes
Q27642349Crystal Structure of the Extracellular Protein Secretion NTPase EpsE of Vibrio cholerae
Q27642447Crystal Structure of the Homolog of the Oncoprotein Gankyrin, an Interactor of Rb and CDK4/6
Q27641598Crystal Structure of the SarS Protein from Staphylococcus aureus
Q57895028Crystal Structure of the tRNA 3′ Processing Endoribonuclease tRNase Z fromThermotoga maritima
Q27644356Crystal Structures of Major Envelope Proteins VP26 and VP28 from White Spot Syndrome Virus Shed Light on Their Evolutionary Relationship
Q27674116Crystal Structures of Protein Glutaminase and Its Pro Forms Converted into Enzyme-Substrate Complex
Q27651312Crystal structure analysis of NP24-I: a thaumatin-like protein
Q27766073Crystal structure and ATPase activity of MutL: implications for DNA repair and mutagenesis
Q59171457Crystal structure and conformational stability of N -acetyl- l -prolyl- l -leucinamide. Comparison between structural and thermophysical data
Q27629468Crystal structure and deletion analysis show that the accessory subunit of mammalian DNA polymerase gamma, Pol gamma B, functions as a homodimer
Q27629132Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gamma
Q27627161Crystal structure and functional dissection of the cytostatic cytokine oncostatin M
Q27639064Crystal structure and mechanism of a calcium-gated potassium channel
Q27640212Crystal structure and site-directed mutagenesis of enzymatic components from Clostridium perfringens iota-toxin
Q33887219Crystal structure at 1.2 A resolution and active site mapping of Escherichia coli peptidyl-tRNA hydrolase
Q27635082Crystal structure at 1.5-A resolution of Pyrus pyrifolia pistil ribonuclease responsible for gametophytic self-incompatibility
Q46478074Crystal structure at 2.2 A resolution of the MHC-related neonatal Fc receptor.
Q27631600Crystal structure at 2.8 A of an FcRn/heterodimeric Fc complex: mechanism of pH-dependent binding
Q24673341Crystal structure of 12-oxophytodienoate reductase 3 from tomato: self-inhibition by dimerization
Q27649412Crystal structure of 5-methylthioribose 1-phosphate isomerase product complex from Bacillus subtilis: Implications for catalytic mechanism
Q27618741Crystal structure of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, a potential target for the development of novel antimicrobial agents
Q37605234Crystal structure of ATF-2/c-Jun and IRF-3 bound to the interferon-beta enhancer
Q27640176Crystal structure of AlgQ2, a macromolecule (alginate)-binding protein of Sphingomonas sp. A1, complexed with an alginate tetrasaccharide at 1.6-A resolution
Q27640146Crystal structure of Bacillus sp. GL1 xanthan lyase, which acts on the side chains of xanthan
Q27620353Crystal structure of Bacillus subtilis YabJ, a purine regulatory protein and member of the highly conserved YjgF family
Q44924242Crystal structure of Bacillus subtilis guanine deaminase: the first domain-swapped structure in the cytidine deaminase superfamily
Q27634627Crystal structure of Bruton's tyrosine kinase domain suggests a novel pathway for activation and provides insights into the molecular basis of X-linked agammaglobulinemia
Q24306553Crystal structure of CD1a in complex with a sulfatide self antigen at a resolution of 2.15 A
Q44948909Crystal structure of CD26/dipeptidyl-peptidase IV in complex with adenosine deaminase reveals a highly amphiphilic interface
Q24564054Crystal structure of Caenorhabditis elegans HER-1 and characterization of the interaction between HER-1 and TRA-2A
Q27640829Crystal structure of CapZ: structural basis for actin filament barbed end capping
Q27639561Crystal structure of ClpA, an Hsp100 chaperone and regulator of ClpAP protease
Q27640028Crystal structure of D-aminoacylase from Alcaligenes faecalis DA1. A novel subset of amidohydrolases and insights into the enzyme mechanism
Q27643076Crystal structure of Dcp1p and its functional implications in mRNA decapping
Q40615901Crystal structure of Dengue virus NS3 protease in complex with a Bowman-Birk inhibitor: implications for flaviviral polyprotein processing and drug design
Q27625486Crystal structure of Escherichia coli CyaY protein reveals a previously unidentified fold for the evolutionarily conserved frataxin family
Q27620464Crystal structure of Escherichia coli PurE, an unusual mutase in the purine biosynthetic pathway
Q24533426Crystal structure of Escherichia coli cystathionine gamma-synthase at 1.5 A resolution
Q24629725Crystal structure of Escherichia coli cytidine triphosphate synthetase, a nucleotide-regulated glutamine amidotransferase/ATP-dependent amidoligase fusion protein and homologue of anticancer and antiparasitic drug targets
Q27641084Crystal structure of Escherichia coli sigmaE with the cytoplasmic domain of its anti-sigma RseA
Q27641632Crystal structure of Escherichia coli thioesterase I/protease I/lysophospholipase L1: consensus sequence blocks constitute the catalytic center of SGNH-hydrolases through a conserved hydrogen bond network
Q27632866Crystal structure of Fab198, an efficient protector of the acetylcholine receptor against myasthenogenic antibodies
Q27640585Crystal structure of GGA2 VHS domain and its implication in plasticity in the ligand binding pocket
Q27641776Crystal structure of HLA-A2 bound to LIR-1, a host and viral major histocompatibility complex receptor
Q27765717Crystal structure of HLA-DR2 (DRA*0101, DRB1*1501) complexed with a peptide from human myelin basic protein
Q27618507Crystal structure of Hck in complex with a Src family-selective tyrosine kinase inhibitor
Q27737553Crystal structure of ICAM-2 reveals a distinctive integrin recognition surface
Q27765333Crystal structure of JNK3: a kinase implicated in neuronal apoptosis
Q27676745Crystal structure of JlpA, a surface-exposed lipoprotein adhesin of Campylobacter jejuni
Q36059479Crystal structure of LAAO from Calloselasma rhodostoma with an L-phenylalanine substrate: insights into structure and mechanism
Q24630452Crystal structure of Leishmania major oligopeptidase B gives insight into the enzymatic properties of a trypanosomatid virulence factor
Q34012966Crystal structure of MC159 reveals molecular mechanism of DISC assembly and FLIP inhibition
Q27617244Crystal structure of MHC class II-associated p41 Ii fragment bound to cathepsin L reveals the structural basis for differentiation between cathepsins L and S.
Q27642975Crystal structure of MO25 alpha in complex with the C terminus of the pseudo kinase STE20-related adaptor
Q27639581Crystal structure of MTH169, a crucial component of phosphoribosylformylglycinamidine synthetase
Q27640988Crystal structure of Mg2+- and Ca2+-bound Gla domain of factor IX complexed with binding protein
Q27621613Crystal structure of NAD+-dependent DNA ligase: modular architecture and functional implications
Q27638894Crystal structure of NC1 domains. Structural basis for type IV collagen assembly in basement membranes
Q41845464Crystal structure of NS-134 in complex with bovine cathepsin B: a two-headed epoxysuccinyl inhibitor extends along the entire active-site cleft.
Q27627085Crystal structure of Omp32, the anion-selective porin from Comamonas acidovorans, in complex with a periplasmic peptide at 2.1 A resolution
Q78578334Crystal structure of PU.1/IRF-4/DNA ternary complex
Q44881153Crystal structure of PapA5, a phthiocerol dimycocerosyl transferase from Mycobacterium tuberculosis.
Q27639527Crystal structure of Pseudomonas fluorescens mannitol 2-dehydrogenase binary and ternary complexes. Specificity and catalytic mechanism
Q24610262Crystal structure of RAIDD death domain implicates potential mechanism of PIDDosome assembly
Q27621335Crystal structure of RNA 3'-terminal phosphate cyclase, a ubiquitous enzyme with unusual topology
Q27644465Crystal structure of RNase T, an exoribonuclease involved in tRNA maturation and end turnover
Q27622721Crystal structure of RPB5, a universal eukaryotic RNA polymerase subunit and transcription factor interaction target
Q27629036Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1
Q30339085Crystal structure of RlmAI: implications for understanding the 23S rRNA G745/G748-methylation at the macrolide antibiotic-binding site.
Q27639465Crystal structure of Rnd3/RhoE: functional implications
Q27729336Crystal structure of SIV matrix antigen and implications for virus assembly
Q27639264Crystal structure of SRP19 in complex with the S domain of SRP RNA and its implication for the assembly of the signal recognition particle
Q36026254Crystal structure of Ski8p, a WD-repeat protein with dual roles in mRNA metabolism and meiotic recombination
Q27640485Crystal structure of Stefin A in complex with cathepsin H: N-terminal residues of inhibitors can adapt to the active sites of endo- and exopeptidases
Q45050478Crystal structure of T-protein of the glycine cleavage system. Cofactor binding, insights into H-protein recognition, and molecular basis for understanding nonketotic hyperglycinemia
Q27648222Crystal structure of T4 endonuclease VII resolving a Holliday junction
Q27765686Crystal structure of Taq DNA polymerase in complex with an inhibitory Fab: the Fab is directed against an intermediate in the helix-coil dynamics of the enzyme
Q33875224Crystal structure of Thermus aquaticus core RNA polymerase at 3.3 A resolution.
Q44785428Crystal structure of TruD, a novel pseudouridine synthase with a new protein fold
Q27642257Crystal structure of YdcE protein from Bacillus subtilis
Q37513233Crystal structure of YjeQ from Thermotoga maritima contains a circularly permuted GTPase domain
Q24539221Crystal structure of a 12 ANK repeat stack from human ankyrinR.
Q27627081Crystal structure of a D-aminopeptidase from Ochrobactrum anthropi, a new member of the 'penicillin-recognizing enzyme' family
Q27642595Crystal structure of a DNA binding protein from the hyperthermophilic euryarchaeonMethanococcus jannaschii
Q27729299Crystal structure of a DNA decamer showing a novel pseudo four-way helix-helix junction
Q25257835Crystal structure of a DNA polymerase sliding clamp from a Gram-positive bacterium
Q27641117Crystal structure of a Fab complex formed with PfMSP1-19, the C-terminal fragment of merozoite surface protein 1 from Plasmodium falciparum: a malaria vaccine candidate
Q27765267Crystal structure of a GCN5-related N-acetyltransferase: Serratia marcescens aminoglycoside 3-N-acetyltransferase
Q24294435Crystal structure of a MARCKS peptide containing the calmodulin-binding domain in complex with Ca2+-calmodulin
Q27733300Crystal structure of a PDZ domain
Q27631597Crystal structure of a Pumilio homology domain
Q27640100Crystal structure of a SEA variant in complex with MHC class II reveals the ability of SEA to crosslink MHC molecules
Q27631591Crystal structure of a SIR2 homolog-NAD complex
Q27765619Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution
Q30475947Crystal structure of a SeqA-N filament: implications for DNA replication and chromosome organization
Q27627292Crystal structure of a T cell receptor bound to an allogeneic MHC molecule
Q27729899Crystal structure of a TFIIB-TBP-TATA-element ternary complex
Q27640257Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde
Q27635332Crystal structure of a Y-family DNA polymerase in action: a mechanism for error-prone and lesion-bypass replication
Q27636769Crystal structure of a bacterial signal peptidase apoenzyme: implications for signal peptide binding and the Ser-Lys dyad mechanism
Q27766053Crystal structure of a bacterial signal peptidase in complex with a beta-lactam inhibitor
Q27748814Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolution
Q30535279Crystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase
Q24301888Crystal structure of a beta-catenin/APC complex reveals a critical role for APC phosphorylation in APC function
Q27629129Crystal structure of a beta-catenin/Tcf complex
Q24646858Crystal structure of a beta-catenin/axin complex suggests a mechanism for the beta-catenin destruction complex
Q27621384Crystal structure of a class I α1,2-mannosidase involved in N-glycan processing and endoplasmic reticulum quality control
Q34324966Crystal structure of a clip-domain serine protease and functional roles of the clip domains
Q27764891Crystal structure of a colicin N fragment suggests a model for toxicity
Q27629908Crystal structure of a complement control protein that regulates both pathways of complement activation and binds heparan sulfate proteoglycans
Q27639508Crystal structure of a complex formed between a snake venom phospholipase A(2) and a potent peptide inhibitor Phe-Leu-Ser-Tyr-Lys at 1.8 A resolution
Q27632851Crystal structure of a complex of a type IA DNA topoisomerase with a single-stranded DNA molecule
Q27641575Crystal structure of a conserved hypothetical protein from Escherichia coli
Q27729820Crystal structure of a conserved protease that binds DNA: the bleomycin hydrolase, Gal6
Q36526307Crystal structure of a dodecameric FMN-dependent UbiX-like decarboxylase (Pad1) from Escherichia coli O157: H7
Q22009026Crystal structure of a heparin- and integrin-binding segment of human fibronectin.
Q27765718Crystal structure of a hepatitis delta virus ribozyme
Q27625221Crystal structure of a heterodimeric complex of RAR and RXR ligand-binding domains
Q27641991Crystal structure of a human Mob1 protein: toward understanding Mob-regulated cell cycle pathways
Q27765744Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision
Q27642420Crystal structure of a hypothetical protein, TT1725, from Thermus thermophilus HB8 at 1.7 A resolution
Q27639466Crystal structure of a laccase from the fungus Trametes versicolor at 1.90-A resolution containing a full complement of coppers
Q27641995Crystal structure of a lysine biosynthesis enzyme, LysX, from Thermus thermophilus HB8
Q22061875Crystal structure of a membrane-bound metalloenzyme that catalyses the biological oxidation of methane
Q27629432Crystal structure of a monocotyledon (maize ZMGlu1) beta-glucosidase and a model of its complex with p-nitrophenyl beta-D-thioglucoside
Q27620084Crystal structure of a multifunctional 2-Cys peroxiredoxin heme-binding protein 23 kDa/proliferation-associated gene product
Q27643094Crystal structure of a myristoylated CAP-23/NAP-22 N-terminal domain complexed with Ca2+/calmodulin
Q27641636Crystal structure of a natural circularly permuted jellyroll protein: 1,3-1,4-beta-D-glucanase from Fibrobacter succinogenes
Q30160291Crystal structure of a nicotinate phosphoribosyltransferase from Thermoplasma acidophilum
Q27639247Crystal structure of a non-canonical low-affinity peptide complexed with MHC class I: a new approach for vaccine design
Q27643826Crystal structure of a novel prokaryotic Ser/Thr kinase and its implication in the Cpx stress response pathway
Q27632935Crystal structure of a novel-type archaeal rubisco with pentagonal symmetry
Q27641053Crystal structure of a nucleoside diphosphate kinase from Bacillus halodenitrificans: coexpression of its activity with a Mn-superoxide dismutase
Q24557184Crystal structure of a pH-regulated luciferase catalyzing the bioluminescent oxidation of an open tetrapyrrole
Q27641505Crystal structure of a phosphatase with a unique substrate binding domain fromThermotoga maritima
Q46858662Crystal structure of a plant immunophilin domain involved in regulation of MDR-type ABC transporters
Q27740210Crystal structure of a pol alpha family replication DNA polymerase from bacteriophage RB69
Q42208861Crystal structure of a polyphosphate kinase and its implications for polyphosphate synthesis
Q36517997Crystal structure of a predicted phosphoribosyltransferase (TT1426) from Thermus thermophilus HB8 at 2.01 A resolution
Q27636119Crystal structure of a procaspase-7 zymogen: mechanisms of activation and substrate binding
Q35546797Crystal structure of a putative HTH-type transcriptional regulator yxaF from Bacillus subtilis.
Q27764895Crystal structure of a recombinant alphaEC domain from human fibrinogen-420
Q27729794Crystal structure of a replication fork single-stranded DNA binding protein (T4 gp32) complexed to DNA
Q54453416Crystal structure of a rhomboid family intramembrane protease.
Q27733702Crystal structure of a sigma 70 subunit fragment from E. coli RNA polymerase
Q28287140Crystal structure of a soluble form of the human T cell coreceptor CD8 at 2.6 A resolution
Q27634793Crystal structure of a soluble form of the intracellular chloride ion channel CLIC1 (NCC27) at 1.4-A resolution
Q27639034Crystal structure of a squalene cyclase in complex with the potential anticholesteremic drug Ro48-8071
Q27637928Crystal structure of a staphylokinase: variant a model for reduced antigenicity
Q27639666Crystal structure of a subcomplex of human transcription factor TFIID formed by TATA binding protein-associated factors hTAF4 (hTAF(II)135) and hTAF12 (hTAF(II)20)
Q27632891Crystal structure of a superantigen bound to MHC class II displays zinc and peptide dependence
Q24290400Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization
Q37697143Crystal structure of a theta-class glutathione transferase.
Q27640623Crystal structure of a transition state mimic for Tdp1 assembled from vanadate, DNA, and a topoisomerase I-derived peptide
Q27640340Crystal structure of a trimeric form of dephosphocoenzyme A kinase from Escherichia coli
Q24336371Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA
Q27732643Crystal structure of a yeast TFIIA/TBP/DNA complex
Q27641730Crystal structure of aclacinomycin methylesterase with bound product analogues: implications for anthracycline recognition and mechanism
Q45146779Crystal structure of an ATPase-active form of Rad51 homolog from Methanococcus voltae. Insights into potassium dependence
Q27736012Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent
Q27622806Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand
Q27618744Crystal structure of an aminoglycoside 6'-N-acetyltransferase: defining the GCN5-related N-acetyltransferase superfamily fold
Q33889677Crystal structure of an angiogenesis inhibitor bound to the FGF receptor tyrosine kinase domain.
Q27625180Crystal structure of an anti-carbohydrate antibody directed against Vibrio cholerae O1 in complex with antigen: Molecular basis for serotype specificity
Q27620205Crystal structure of an archaebacterial DNA polymerase
Q36476819Crystal structure of an enhancer of rudimentary homolog (ERH) at 2.1 Angstroms resolution
Q27636131Crystal structure of an ephrin ectodomain
Q27729413Crystal structure of an integrin-binding fragment of vascular cell adhesion molecule-1 at 1.8 A resolution
Q27648905Crystal structure of anapoform ofShigella flexneriArsH protein with an NADPH-dependent FMN reductase activity
Q27627174Crystal structure of archaeal RNase HII: a homologue of human major RNase H
Q27646865Crystal structure of archaeal highly thermostable L-aspartate dehydrogenase/NAD/citrate ternary complex
Q30163863Crystal structure of archaeal ribonuclease P protein Ph1771p from Pyrococcus horikoshii OT3: an archaeal homolog of eukaryotic ribonuclease P protein Rpp29
Q27639126Crystal structure of archaeosine tRNA-guanine transglycosylase
Q27639761Crystal structure of bacterial multidrug efflux transporter AcrB
Q27632566Crystal structure of baculovirus P35 reveals a novel conformational change in the reactive site loop after caspase cleavage
Q27617943Crystal structure of baculovirus P35: role of a novel reactive site loop in apoptotic caspase inhibition
Q27748831Crystal structure of barley 1,3-1,4-beta-glucanase at 2.0-A resolution and comparison with Bacillus 1,3-1,4-beta-glucanase
Q24533145Crystal structure of beta-ketoacyl-acyl carrier protein synthase II from E.coli reveals the molecular architecture of condensing enzymes
Q27639089Crystal structure of beta1,4-galactosyltransferase complex with UDP-Gal reveals an oligosaccharide acceptor binding site
Q27765727Crystal structure of botulinum neurotoxin type A and implications for toxicity
Q27758879Crystal structure of calsequestrin from rabbit skeletal muscle sarcoplasmic reticulum
Q27748807Crystal structure of carboxylesterase from Pseudomonas fluorescens, an alpha/beta hydrolase with broad substrate specificity
Q27619622Crystal structure of cardosin A, a glycosylated and Arg-Gly-Asp-containing aspartic proteinase from the flowers of Cynara cardunculus L
Q27640305Crystal structure of carnitine acetyltransferase and implications for the catalytic mechanism and fatty acid transport
Q27730412Crystal structure of casein kinase-1, a phosphate-directed protein kinase
Q27641840Crystal structure of caspase-2, apical initiator of the intrinsic apoptotic pathway
Q27631031Crystal structure of cis-prenyl chain elongating enzyme, undecaprenyl diphosphate synthase
Q27620461Crystal structure of colicin E3 immunity protein: an inhibitor of a ribosome-inactivating RNase
Q27636740Crystal structure of colicin E3: implications for cell entry and ribosome inactivation
Q27639164Crystal structure of conserved hypothetical protein Aq1575 from Aquifex aeolicus
Q53441134Crystal structure of constitutively monomeric E. coli Hsp33 mutant with chaperone activity.
Q27630604Crystal structure of cytochrome P450 14 -sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with azole inhibitors
Q27617443Crystal structure of deoxycytidylate hydroxymethylase from bacteriophage T4, a component of the deoxyribonucleoside triphosphate-synthesizing complex
Q27629628Crystal structure of dihydropyrimidine dehydrogenase, a major determinant of the pharmacokinetics of the anti-cancer drug 5-fluorouracil
Q27632948Crystal structure of diisopropylfluorophosphatase from Loligo vulgaris
Q24568241Crystal structure of dimeric human ciliary neurotrophic factor determined by MAD phasing
Q27641988Crystal structure of dissimilatory sulfite reductase D (DsrD) protein--possible interaction with B- and Z-DNA by its winged-helix motif
Q24562017Crystal structure of elongation factor P from Thermus thermophilus HB8
Q38319400Crystal structure of enteric adenovirus serotype 41 short fiber head
Q27748178Crystal structure of ferrochelatase: the terminal enzyme in heme biosynthesis
Q27627811Crystal structure of fibroblast growth factor 9 reveals regions implicated in dimerization and autoinhibition
Q27733370Crystal structure of firefly luciferase throws light on a superfamily of adenylate-forming enzymes
Q27729481Crystal structure of glycyl-tRNA synthetase from Thermus thermophilus
Q27729480Crystal structure of histidyl-tRNA synthetase from Escherichia coli complexed with histidyl-adenylate
Q41166663Crystal structure of hormone-bound atrial natriuretic peptide receptor extracellular domain: rotation mechanism for transmembrane signal transduction
Q27636683Crystal structure of human AUH protein, a single-stranded RNA binding homolog of enoyl-CoA hydratase
Q27733275Crystal structure of human Charcot-Leyden crystal protein, an eosinophil lysophospholipase, identifies it as a new member of the carbohydrate-binding family of galectins
Q36458171Crystal structure of human D-amino acid oxidase: context-dependent variability of the backbone conformation of the VAAGL hydrophobic stretch located at the si-face of the flavin ring.
Q27641304Crystal structure of human DJ-1, a protein associated with early onset Parkinson's disease
Q27637348Crystal structure of human L-isoaspartyl methyltransferase
Q27639102Crystal structure of human MMP9 in complex with a reverse hydroxamate inhibitor
Q24291702Crystal structure of human PEDF, a potent anti-angiogenic and neurite growth-promoting factor
Q27617901Crystal structure of human T cell leukemia virus type 1 gp21 ectodomain crystallized as a maltose-binding protein chimera reveals structural evolution of retroviral transmembrane proteins
Q27736500Crystal structure of human UP1, the domain of hnRNP A1 that contains two RNA-recognition motifs
Q24630615Crystal structure of human alpha-tocopherol transfer protein bound to its ligand: implications for ataxia with vitamin E deficiency
Q34478920Crystal structure of human apolipoprotein A-I: insights into its protective effect against cardiovascular diseases.
Q24602248Crystal structure of human beta-hexosaminidase B: understanding the molecular basis of Sandhoff and Tay-Sachs disease
Q27619037Crystal structure of human bleomycin hydrolase, a self-compartmentalizing cysteine protease
Q22253419Crystal structure of human branched-chain alpha-ketoacid dehydrogenase and the molecular basis of multienzyme complex deficiency in maple syrup urine disease
Q42846520Crystal structure of human cathepsin S.
Q27731417Crystal structure of human chorionic gonadotropin
Q24683471Crystal structure of human cyclin K, a positive regulator of cyclin-dependent kinase 9
Q34397220Crystal structure of human cystatin D, a cysteine peptidase inhibitor with restricted inhibition profile
Q27625397Crystal structure of human frataxin
Q27618490Crystal structure of human gastric lipase and model of lysosomal acid lipase, two lipolytic enzymes of medical interest
Q28115622Crystal structure of human indoleamine 2,3-dioxygenase: catalytic mechanism of O2 incorporation by a heme-containing dioxygenase
Q24562991Crystal structure of human lithostathine, the pancreatic inhibitor of stone formation
Q27619507Crystal structure of human mitochondrial NAD(P)(+)-dependent malic enzyme: a new class of oxidative decarboxylases
Q27655739Crystal structure of human mitochondrial acyl-CoA thioesterase (ACOT2)
Q27734819Crystal structure of human mitochondrial single-stranded DNA binding protein at 2.4 A resolution
Q24653008Crystal structure of human p32, a doughnut-shaped acidic mitochondrial matrix protein
Q24291728Crystal structure of human protein kinase CK2: insights into basic properties of the CK2 holoenzyme
Q27641836Crystal structure of human purine nucleoside phosphorylase complexed with acyclovir
Q24318752Crystal structure of human recombinant ornithine aminotransferase
Q24302273Crystal structure of human renal dipeptidase involved in beta-lactam hydrolysis
Q27625375Crystal structure of human squalene synthase. A key enzyme in cholesterol biosynthesis
Q27625275Crystal structure of human stem cell factor: implication for stem cell factor receptor dimerization and activation
Q28248182Crystal structure of human thimet oligopeptidase provides insight into substrate recognition, regulation, and localization
Q34405959Crystal structure of human vacuolar protein sorting protein 29 reveals a phosphodiesterase/nuclease-like fold and two protein-protein interaction sites.
Q27637549Crystal structure of imaginal disc growth factor-2. A member of a new family of growth-promoting glycoproteins from Drosophila melanogaster
Q27635288Crystal structure of imidazole glycerol phosphate synthase: a tunnel through a (beta/alpha)8 barrel joins two active sites
Q42019139Crystal structure of low-molecular-weight protein tyrosine phosphatase from Mycobacterium tuberculosis at 1.9-A resolution
Q27626471Crystal structure of mammalian poly(A) polymerase in complex with an analog of ATP
Q27639624Crystal structure of microbial transglutaminase from Streptoverticillium mobaraense
Q27765681Crystal structure of mouse H2-M
Q27638915Crystal structure of murine sCEACAM1a[1,4]: a coronavirus receptor in the CEA family
Q27742069Crystal structure of murine/human Ubc9 provides insight into the variability of the ubiquitin-conjugating system
Q27633373Crystal structure of negative cofactor 2 recognizing the TBP-DNA transcription complex
Q24564277Crystal structure of nickel-containing superoxide dismutase reveals another type of active site
Q27637481Crystal structure of non-allosteric L-lactate dehydrogenase from Lactobacillus pentosus at 2.3 A resolution: specific interactions at subunit interfaces
Q27630239Crystal structure of outer surface protein C (OspC) from the Lyme disease spirochete, Borrelia burgdorferi
Q27733875Crystal structure of p38 mitogen-activated protein kinase
Q27741953Crystal structure of phosphoadenylyl sulphate (PAPS) reductase: a new family of adenine nucleotide alpha hydrolases
Q27689554Crystal structure of phosphopantothenate synthetase from Thermococcus kodakarensis
Q27638842Crystal structure of plant pectin methylesterase
Q27748903Crystal structure of porcine cathepsin H determined at 2.1 A resolution: location of the mini-chain C-terminal carboxyl group defines cathepsin H aminopeptidase function
Q30163900Crystal structure of pyrogallol-phloroglucinol transhydroxylase, an Mo enzyme capable of intermolecular hydroxyl transfer between phenols
Q28578888Crystal structure of rat carnitine palmitoyltransferase II (CPT-II)
Q27637514Crystal structure of rat short chain acyl-CoA dehydrogenase complexed with acetoacetyl-CoA: comparison with other acyl-CoA dehydrogenases
Q27639495Crystal structure of recombinant human interleukin-22
Q42844591Crystal structure of recombinant triosephosphate isomerase from Bacillus stearothermophilus. An analysis of potential thermostability factors in six isomerases with known three-dimensional structures points to the importance of hydrophobic interacti
Q27628241Crystal structure of red sea bream transglutaminase
Q27637218Crystal structure of reovirus attachment protein sigma1 reveals evolutionary relationship to adenovirus fiber
Q27637557Crystal structure of reverse gyrase: insights into the positive supercoiling of DNA
Q36526216Crystal structure of ribosomal protein L27 from Thermus thermophilus HB8
Q27621598Crystal structure of ribosomal protein L4 shows RNA-binding sites for ribosome incorporation and feedback control of the S10 operon
Q27637902Crystal structure of sTALL-1 reveals a virus-like assembly of TNF family ligands
Q47932220Crystal structure of severe acute respiratory syndrome coronavirus spike protein fusion core
Q27641336Crystal structure of soybean 11S globulin: Glycinin A3B4 homohexamer
Q40541096Crystal structure of species D adenovirus fiber knobs and their sialic acid binding sites
Q42846151Crystal structure of spinach plastocyanin at 1.7 A resolution
Q21256429Crystal structure of subunit VPS25 of the endosomal trafficking complex ESCRT-II
Q27732798Crystal structure of tRNA-guanine transglycosylase: RNA modification by base exchange
Q27628688Crystal structure of the "cab"-type beta class carbonic anhydrase from the archaeon Methanobacterium thermoautotrophicum
Q27641424Crystal structure of the 2'-5' RNA ligase from Thermus thermophilus HB8
Q27642623Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral protein 2'-5'-oligoadenylate synthetase
Q27650479Crystal structure of the 25 kDa subunit of human cleavage factor Im
Q27639530Crystal structure of the 47-kDa lipoprotein of Treponema pallidum reveals a novel penicillin-binding protein
Q40419982Crystal structure of the 65-kilodalton heat shock protein, chaperonin 60.2, of Mycobacterium tuberculosis
Q27619033Crystal structure of the Atx1 metallochaperone protein at 1.02 A resolution
Q27639656Crystal structure of the BEACH domain reveals an unusual fold and extensive association with a novel PH domain
Q22003945Crystal structure of the BTB domain from PLZF
Q27638863Crystal structure of the Bacillus stearothermophilus anti-sigma factor SpoIIAB with the sporulation sigma factor sigmaF
Q41866374Crystal structure of the Bowman-Birk Inhibitor from Vigna unguiculata seeds in complex with beta-trypsin at 1.55 A resolution and its structural properties in association with proteinases.
Q27641049Crystal structure of the C-terminal domain of Ebola virus VP30 reveals a role in transcription and nucleocapsid association
Q27644658Crystal structure of the C-terminal domain of splicing factor Prp8 carrying retinitis pigmentosa mutants
Q27630607Crystal structure of the C-terminal domain of the RAP74 subunit of human transcription factor IIF
Q27639906Crystal structure of the C-terminal half of tropomodulin and structural basis of actin filament pointed-end capping
Q34320475Crystal structure of the C-terminal peptidoglycan-binding domain of human peptidoglycan recognition protein Ialpha
Q27764892Crystal structure of the C2 domain from protein kinase C-delta
Q27639250Crystal structure of the CCTgamma apical domain: implications for substrate binding to the eukaryotic cytosolic chaperonin
Q27617898Crystal structure of the CD2-binding domain of CD58 (lymphocyte function-associated antigen 3) at 1.8-A resolution
Q27748800Crystal structure of the CDK4/6 inhibitory protein p18INK4c provides insights into ankyrin-like repeat structure/function and tumor-derived p16INK4 mutations
Q27619948Crystal structure of the DNA nucleotide excision repair enzyme UvrB from Thermus thermophilus
Q27639838Crystal structure of the DNA-binding domain from Ndt80, a transcriptional activator required for meiosis in yeast
Q27735034Crystal structure of the DNA-binding domain of Mbp1, a transcription factor important in cell-cycle control of DNA synthesis
Q36458248Crystal structure of the DUF16 domain of MPN010 from Mycoplasma pneumoniae
Q22004024Crystal structure of the Dbl and pleckstrin homology domains from the human Son of sevenless protein
Q33978574Crystal structure of the Deinococcus radiodurans single-stranded DNA-binding protein suggests a mechanism for coping with DNA damage.
Q27732066Crystal structure of the DsbA protein required for disulphide bond formation in vivo
Q27766228Crystal structure of the Ebola virus membrane fusion subunit, GP2, from the envelope glycoprotein ectodomain
Q27638843Crystal structure of the Escherichia coli SbmC protein that protects cells from the DNA replication inhibitor microcin B17
Q27637525Crystal structure of the GABAA-receptor-associated protein, GABARAP
Q24657246Crystal structure of the GTPase-activating protein-related domain from IQGAP1
Q27730368Crystal structure of the GreA transcript cleavage factor from Escherichia coli
Q27625292Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: A model for viral DNA binding
Q24800287Crystal structure of the Habc domain of neuronal syntaxin from the squid Loligo pealei reveals conformational plasticity at its C-terminus
Q27629452Crystal structure of the Holliday junction migration motor protein RuvB from Thermus thermophilus HB8
Q27630261Crystal structure of the Lrp-like transcriptional regulator from the archaeon Pyrococcus furiosus
Q27639326Crystal structure of the Ly49I natural killer cell receptor reveals variability in dimerization mode within the Ly49 family
Q27642013Crystal structure of the M1 protein-binding domain of the influenza A virus nuclear export protein (NEP/NS2)
Q24648873Crystal structure of the MAP kinase binding domain and the catalytic domain of human MKP5
Q27618584Crystal structure of the MHC class I homolog MIC-A, a gammadelta T cell ligand
Q27641078Crystal structure of the MazE/MazF complex: molecular bases of antidote-toxin recognition
Q27647330Crystal structure of the MgtE Mg2+ transporter
Q27642971Crystal structure of the Mor protein of bacteriophage Mu, a member of the Mor/C family of transcription activators
Q27640334Crystal structure of the MurG:UDP-GlcNAc complex reveals common structural principles of a superfamily of glycosyltransferases
Q30350828Crystal structure of the NAD biosynthetic enzyme quinolinate synthase.
Q24531430Crystal structure of the OpcA integral membrane adhesin from Neisseria meningitidis
Q27732607Crystal structure of the PI 3-kinase p85 amino-terminal SH2 domain and its phosphopeptide complexes
Q24324478Crystal structure of the PTPL1/FAP-1 human tyrosine phosphatase mutated in colorectal cancer: evidence for a second phosphotyrosine substrate recognition pocket
Q40100747Crystal structure of the PsbP protein of photosystem II from Nicotiana tabacum.
Q27641938Crystal structure of the PsbQ protein of photosystem II from higher plants
Q27729334Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid
Q35846264Crystal structure of the RNA binding ribosomal protein L1 from Thermus thermophilus
Q27486092Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus
Q27639893Crystal structure of the RuvA-RuvB complex: a structural basis for the Holliday junction migrating motor machinery
Q27641803Crystal structure of the SF3 helicase from adeno-associated virus type 2
Q27748912Crystal structure of the Saccharomyces cerevisiae ubiquitin-conjugating enzyme Rad6 at 2.6 A resolution
Q27632217Crystal structure of the SarR protein from Staphylococcus aureus
Q27734750Crystal structure of the Src family tyrosine kinase Hck
Q27639866Crystal structure of the TSP-1 type 1 repeats
Q24597643Crystal structure of the Xrcc4 DNA repair protein and implications for end joining
Q27641914Crystal structure of the YajQ protein from Haemophilus influenzae reveals a tandem of RNP-like domains
Q24682960Crystal structure of the YchF protein reveals binding sites for GTP and nucleic acid
Q24805132Crystal structure of the YffB protein from Pseudomonas aeruginosa suggests a glutathione-dependent thiol reductase function
Q37583312Crystal structure of the YgfZ protein from Escherichia coli suggests a folate-dependent regulatory role in one-carbon metabolism.
Q29616450Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog
Q28569020Crystal structure of the agrin-responsive immunoglobulin-like domains 1 and 2 of the receptor tyrosine kinase MuSK
Q27622336Crystal structure of the allergen Equ c 1. A dimeric lipocalin with restricted IgE-reactive epitopes
Q24672517Crystal structure of the alpha appendage of AP-2 reveals a recruitment platform for clathrin-coat assembly
Q27633586Crystal structure of the alpha-actinin rod reveals an extensive torsional twist
Q27641666Crystal structure of the amino-terminal microtubule-binding domain of end-binding protein 1 (EB1)
Q24535966Crystal structure of the ankyrin repeat domain of Bcl-3: a unique member of the IkappaB protein family.
Q27639109Crystal structure of the anti-His tag antibody 3D5 single-chain fragment complexed to its antigen
Q27748928Crystal structure of the anti-fungal target N-myristoyl transferase
Q27630994Crystal structure of the archaeal holliday junction resolvase Hjc and implications for DNA recognition
Q27625163Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export
Q27667225Crystal structure of the branching enzyme I (BEI) from Oryza sativa L with implications for catalysis and substrate binding
Q27625023Crystal structure of the calcium pump of sarcoplasmic reticulum at 2.6 A resolution
Q24304876Crystal structure of the calcium-stabilized human factor IX Gla domain bound to a conformation-specific anti-factor IX antibody
Q27637854Crystal structure of the carbohydrate recognition domain of p58/ERGIC-53, a protein involved in glycoprotein export from the endoplasmic reticulum
Q38294458Crystal structure of the catalytic domain of Japanese encephalitis virus NS3 helicase/nucleoside triphosphatase at a resolution of 1.8 A.
Q27642972Crystal structure of the catalytic domain of RluD, the only rRNA pseudouridine synthase required for normal growth of Escherichia coli
Q27638927Crystal structure of the catalytic domain of a human thioredoxin-like protein
Q24294862Crystal structure of the catalytic domain of human MAP kinase phosphatase 5: structural insight into constitutively active phosphatase
Q24600266Crystal structure of the catalytic domain of human complement c1s: a serine protease with a handle
Q27765696Crystal structure of the catalytic domain of protein-tyrosine phosphatase SHP-1
Q27757908Crystal structure of the catalytic domain of the human cell cycle control phosphatase, Cdc25A
Q22253264Crystal structure of the catalytic portion of human HMG-CoA reductase: insights into regulation of activity and catalysis
Q24645314Crystal structure of the collagen triple helix model [(Pro-Pro-Gly)(10)](3)
Q27639005Crystal structure of the complex between calyculin A and the catalytic subunit of protein phosphatase 1
Q27760510Crystal structure of the complex of diphtheria toxin with an extracellular fragment of its receptor
Q46797002Crystal structure of the complex of group I PLA2 with a group II-specific peptide Leu-Ala-Ile-Tyr-Ser (LAIYS) at 2.6 A resolution
Q24336554Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain
Q24631369Crystal structure of the conserved core of protein arginine methyltransferase PRMT3
Q24602247Crystal structure of the conserved core of the herpes simplex virus transcriptional regulatory protein VP16
Q27619724Crystal structure of the conserved subdomain of human protein SRP54M at 2.1 A resolution: evidence for the mechanism of signal peptide binding
Q34376013Crystal structure of the cysteine-rich secretory protein stecrisp reveals that the cysteine-rich domain has a K+ channel inhibitor-like fold.
Q22008781Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12
Q27620244Crystal structure of the cytosolic C2A-C2B domains of synaptotagmin III. Implications for Ca(+2)-independent snare complex interaction
Q27747193Crystal structure of the delta' subunit of the clamp-loader complex of E. coli DNA polymerase III
Q27734768Crystal structure of the dihaem cytochrome c4 from Pseudomonas stutzeri determined at 2.2A resolution
Q24555777Crystal structure of the dimeric extracellular domain of human carbonic anhydrase XII, a bitopic membrane protein overexpressed in certain cancer tumor cells
Q27639498Crystal structure of the dinuclear zinc aminopeptidase PepV from Lactobacillus delbrueckii unravels its preference for dipeptides
Q27631334Crystal structure of the eosinophil major basic protein at 1.8 A. An atypical lectin with a paradigm shift in specificity
Q30439454Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase
Q27733440Crystal structure of the extracellular domain from P0, the major structural protein of peripheral nerve myelin
Q27636573Crystal structure of the extracellular domain of mouse RANK ligand at 2.2-A resolution
Q24291661Crystal structure of the extracellular segment of integrin alpha Vbeta3
Q27622456Crystal structure of the ffh and EF-G binding sites in the conserved domain IV of Escherichia coli 4.5S RNA
Q28902946Crystal structure of the flagellar sigma/anti-sigma complex sigma(28)/FlgM reveals an intact sigma factor in an inactive conformation
Q27621902Crystal structure of the functional domain of the splicing factor Prp18
Q27749090Crystal structure of the hCASK PDZ domain reveals the structural basis of class II PDZ domain target recognition
Q27620078Crystal structure of the helicase domain from the replicative helicase-primase of bacteriophage T7
Q24336313Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor
Q27629331Crystal structure of the hexameric traffic ATPase of the Helicobacter pylori type IV secretion system
Q24670433Crystal structure of the homo-tetrameric DNA binding domain of Escherichia coli single-stranded DNA-binding protein determined by multiwavelength x-ray diffraction on the selenomethionyl protein at 2.9-A resolution
Q33581257Crystal structure of the human ATP-dependent splicing and export factor UAP56.
Q27641114Crystal structure of the human CCA-adding enzyme: insights into template-independent polymerization
Q27650817Crystal structure of the human Fe65-PTB1 domain
Q27628348Crystal structure of the human acyl protein thioesterase I from a single X-ray data set to 1.5 A
Q24293072Crystal structure of the human angiotensin-converting enzyme-lisinopril complex
Q27643263Crystal structure of the human carboxypeptidase N (kininase I) catalytic domain
Q27766423Crystal structure of the human high-affinity IgE receptor
Q53624433Crystal structure of the human monocyte-activating receptor, "Group 2" leukocyte Ig-like receptor A5 (LILRA5/LIR9/ILT11).
Q27641970Crystal structure of the human natural killer (NK) cell activating receptor NKp46 reveals structural relationship to other leukocyte receptor complex immunoreceptors
Q27631386Crystal structure of the human natural killer cell inhibitory receptor KIR2DL1-HLA-Cw4 complex
Q27634739Crystal structure of the human nuclear cap binding complex
Q27766356Crystal structure of the human ubiquitin-like protein NEDD8 and interactions with ubiquitin pathway enzymes
Q36280329Crystal structure of the hydroxylase component of methane monooxygenase from Methylosinus trichosporium OB3b
Q27627715Crystal structure of the iron-dependent regulator from Mycobacterium tuberculosis at 2.0-A resolution reveals the Src homology domain 3-like fold and metal binding function of the third domain
Q27625343Crystal structure of the lambda repressor C-terminal domain provides a model for cooperative operator binding
Q27729697Crystal structure of the large fragment of Thermus aquaticus DNA polymerase I at 2.5-A resolution: structural basis for thermostability
Q27730245Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha
Q24599743Crystal structure of the matrix protein VP40 from Ebola virus
Q35024135Crystal structure of the moloney murine leukemia virus RNase H domain
Q27641663Crystal structure of the monomeric isocitrate dehydrogenase in the presence of NADP+: insight into the cofactor recognition, catalysis, and evolution
Q27629230Crystal structure of the mouse p53 core DNA-binding domain at 2.7 A resolution
Q27642021Crystal structure of the nickel-responsive transcription factor NikR
Q22122355Crystal structure of the nucleosome core particle at 2.8 A resolution
Q24535780Crystal structure of the outer membrane protease OmpT from Escherichia coli suggests a novel catalytic site
Q24336704Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex
Q24533405Crystal structure of the phosphatidylinositol 3,4-bisphosphate-binding pleckstrin homology (PH) domain of tandem PH-domain-containing protein 1 (TAPP1): molecular basis of lipid specificity
Q27634553Crystal structure of the processivity clamp loader gamma (gamma) complex of E. coli DNA polymerase III
Q27640057Crystal structure of the protease domain of a heat-shock protein HtrA from Thermotoga maritima
Q47880819Crystal structure of the quorum-sensing protein TraM and its interaction with the transcriptional regulator TraR.
Q27640589Crystal structure of the receptor-binding domain of human B7-2: Insights into organization and signaling
Q27632659Crystal structure of the regulatory subunit H of the V-type ATPase of Saccharomyces cerevisiae
Q27621449Crystal structure of the ribonucleoprotein core of the signal recognition particle
Q27622538Crystal structure of the ribosome recycling factor from Escherichia coli
Q27666918Crystal structure of the sensory domain ofEscherichia coliCadC, a member of the ToxR-like protein family
Q27764897Crystal structure of the simian immunodeficiency virus (SIV) gp41 core: conserved helical interactions underlie the broad inhibitory activity of gp41 peptides
Q27634538Crystal structure of the soluble form of equinatoxin II, a pore-forming toxin from the sea anemone Actinia equina
Q24533612Crystal structure of the soluble form of the human fcgamma-receptor IIb: a new member of the immunoglobulin superfamily at 1.7 A resolution
Q41978633Crystal structure of the specific DNA-binding domain of Tc3 transposase of C.elegans in complex with transposon DNA.
Q24336733Crystal structure of the spliceosomal U2B"-U2A' protein complex bound to a fragment of U2 small nuclear RNA
Q27637529Crystal structure of the stimulatory complex of GTP cyclohydrolase I and its feedback regulatory protein GFRP.
Q24297170Crystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpoint
Q27757284Crystal structure of the tetramerization domain of the Shaker potassium channel
Q27634690Crystal structure of the tumor-promoter okadaic acid bound to protein phosphatase-1
Q27618173Crystal structure of the two-RRM domain of hnRNP A1 (UP1) complexed with single-stranded telomeric DNA
Q27730800Crystal structure of the tyrosine kinase domain of the human insulin receptor
Q27748898Crystal structure of the tyrosine phosphatase SHP-2
Q27619350Crystal structure of the vesicular transport protein Sec17: implications for SNAP function in SNARE complex disassembly
Q27733390Crystal structure of the wide-spectrum binuclear zinc beta-lactamase from Bacteroides fragilis
Q27748897Crystal structure of the yeast MATalpha2/MCM1/DNA ternary complex
Q27733373Crystal structure of the yeast cell-cycle control protein, p13suc1, in a strand-exchanged dimer
Q27638191Crystal structure of the yeast cytochrome bc1 complex with its bound substrate cytochrome c
Q27729754Crystal structure of the zeta isoform of the 14-3-3 protein
Q27641014Crystal structure of theDrosophilaMago nashi–Y14 complex
Q27636213Crystal structure of thermostable DNA photolyase: Pyrimidine-dimer recognition mechanism
Q89540112Crystal structure of thioredoxin 1 from Cryptococcus neoformans at 1.8 Å resolution shows unexpected plasticity of the loop preceding the catalytic site
Q27746886Crystal structure of truncated human apolipoprotein A-I suggests a lipid-bound conformation
Q27620667Crystal structure of trypanosoma cruzi tyrosine aminotransferase: Substrate specificity is influenced by cofactor binding mode
Q27733335Crystal structure of turnip yellow mosaic virus
Q27618470Crystal structure of two CD46 domains reveals an extended measles virus-binding surface
Q38310832Crystal structure of unsaturated glucuronyl hydrolase complexed with substrate: molecular insights into its catalytic reaction mechanism
Q34321429Crystal structure of unsaturated glucuronyl hydrolase, responsible for the degradation of glycosaminoglycan, from Bacillus sp. GL1 at 1.8 A resolution
Q27639172Crystal structure of vesicular stomatitis virus matrix protein
Q27626916Crystal structure of viral serpin crmA provides insights into its mechanism of cysteine proteinase inhibition
Q27641649Crystal structure of von Willebrand factor A1 domain complexed with snake venom, bitiscetin: insight into glycoprotein Ibalpha binding mechanism induced by snake venom proteins
Q43084378Crystal structure of yeast Sis1 peptide-binding fragment and Hsp70 Ssa1 C-terminal complex
Q27640699Crystal structure of yeast cytosine deaminase. Insights into enzyme mechanism and evolution
Q51182921Crystal structure of yeast mitochondrial outer membrane translocon member Tom70p.
Q27644383Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env
Q27642247Crystal structures of 3-methyladenine DNA glycosylase MagIII and the recognition of alkylated bases
Q27638180Crystal structures of 7-methylguanosine 5'-triphosphate (m(7)GTP)- and P(1)-7-methylguanosine-P(3)-adenosine-5',5'-triphosphate (m(7)GpppA)-bound human full-length eukaryotic initiation factor 4E: biological importance of the C-terminal flexible reg
Q27640113Crystal structures of C4 form maize and quaternary complex of E. coli phosphoenolpyruvate carboxylases
Q27764882Crystal structures of Flavobacterium glycosylasparaginase. An N-terminal nucleophile hydrolase activated by intramolecular proteolysis
Q27639263Crystal structures of MAP kinase p38 complexed to the docking sites on its nuclear substrate MEF2A and activator MKK3b
Q24529860Crystal structures of Mycobacterium tuberculosis RecA and its complex with ADP-AlF(4): implications for decreased ATPase activity and molecular aggregation
Q27635335Crystal structures of NK1-heparin complexes reveal the basis for NK1 activity and enable engineering of potent agonists of the MET receptor.
Q31061057Crystal structures of Nipah and Hendra virus fusion core proteins
Q27637579Crystal structures of RAE-1beta and its complex with the activating immunoreceptor NKG2D
Q36476896Crystal structures of RsbQ, a stress-response regulator in Bacillus subtilis
Q24293341Crystal structures of S100A6 in the Ca(2+)-free and Ca(2+)-bound states: the calcium sensor mechanism of S100 proteins revealed at atomic resolution
Q50076210Crystal structures of Salmonella typhimurium biodegradative threonine deaminase and its complex with CMP provide structural insights into ligand-induced oligomerization and enzyme activation.
Q27629827Crystal structures of SarA, a pleiotropic regulator of virulence genes in S. aureus
Q42646107Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding.
Q27732927Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ
Q27634518Crystal structures of a novel ferric reductase from the hyperthermophilic archaeon Archaeoglobus fulgidus and its complex with NADP+
Q27765985Crystal structures of a series of RNA aptamers complexed to the same protein target
Q27637560Crystal structures of a template-independent DNA polymerase: murine terminal deoxynucleotidyltransferase
Q27625381Crystal structures of apo- and holo-bovine alpha-lactalbumin at 2. 2-A resolution reveal an effect of calcium on inter-lobe interactions
Q27629361Crystal structures of bovine beta-lactoglobulin in the orthorhombic space group C222(1). Structural differences between genetic variants A and B and features of the Tanford transition
Q45063418Crystal structures of bovine odorant-binding protein in complex with odorant molecules.
Q27627684Crystal structures of cytochrome P450nor and its mutants (Ser286-->Val, Thr) in the ferric resting state at cryogenic temperature: a comparative analysis with monooxygenase cytochrome P450s
Q27642768Crystal structures of decorated xylooligosaccharides bound to a family 10 xylanase from Streptomyces olivaceoviridis E-86
Q27641843Crystal structures of engrailed homeodomain mutants: implications for stability and dynamics
Q27765262Crystal structures of eukaryotic translation initiation factor 5A from Methanococcus jannaschii at 1.8 A resolution
Q27745853Crystal structures of fragment D from human fibrinogen and its crosslinked counterpart from fibrin
Q27733380Crystal structures of guinea-pig, goat and bovine alpha-lactalbumin highlight the enhanced conformational flexibility of regions that are significant for its action in lactose synthase
Q24532111Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation
Q54456467Crystal structures of human tissue kallikrein 4: activity modulation by a specific zinc binding site.
Q27627633Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA
Q27633600Crystal structures of mitochondrial processing peptidase reveal the mode for specific cleavage of import signal sequences
Q24607519Crystal structures of murine carnitine acetyltransferase in ternary complexes with its substrates
Q27733369Crystal structures of murine polyomavirus in complex with straight-chain and branched-chain sialyloligosaccharide receptor fragments
Q29616842Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation.
Q27729401Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase
Q24669818Crystal structures of photosynthetic reaction center and high-potential iron-sulfur protein from Thermochromatium tepidum: thermostability and electron transfer
Q36526277Crystal structures of possible lysine decarboxylases from Thermus thermophilus HB8
Q27654091Crystal structures of respiratory pathogen neuraminidases
Q27628756Crystal structures of ribosome anti-association factor IF6
Q27627170Crystal structures of substrate binding to Bacillus subtilis holo-(acyl carrier protein) synthase reveal a novel trimeric arrangement of molecules resulting in three active sites
Q33714478Crystal structures of the BlaI repressor from Staphylococcus aureus and its complex with DNA: insights into transcriptional regulation of the bla and mec operons
Q27640116Crystal structures of the BtuF periplasmic-binding protein for vitamin B12 suggest a functionally important reduction in protein mobility upon ligand binding
Q34828345Crystal structures of the DsbG disulfide isomerase reveal an unstable disulfide.
Q38325401Crystal structures of the HIV-1 inhibitory cyanobacterial protein MVL free and bound to Man3GlcNAc2: structural basis for specificity and high-affinity binding to the core pentasaccharide from n-linked oligomannoside
Q27630654Crystal structures of the HslVU peptidase-ATPase complex reveal an ATP-dependent proteolysis mechanism
Q27639895Crystal structures of the Pyrococcus abyssi Sm core and its complex with RNA. Common features of RNA binding in archaea and eukarya
Q22010755Crystal structures of the XLP protein SAP reveal a class of SH2 domains with extended, phosphotyrosine-independent sequence recognition
Q27620579Crystal structures of the membrane-binding C2 domain of human coagulation factor V
Q27732646Crystal structures of the trimeric human immunodeficiency virus type 1 matrix protein: implications for membrane association and assembly
Q36476624Crystal structures of the tryptophan repressor binding protein WrbA and complexes with flavin mononucleotide
Q27749022Crystal structures of two I-Ad-peptide complexes reveal that high affinity can be achieved without large anchor residues
Q27639794Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs
Q42674861Crystal structures of two bacterial 3-hydroxy-3-methylglutaryl-CoA lyases suggest a common catalytic mechanism among a family of TIM barrel metalloenzymes cleaving carbon-carbon bonds
Q27749621Crystal structures of two tropinone reductases: different reaction stereospecificities in the same protein fold
Q27477662Crystallographic Identification of a Noncompetitive Inhibitor Binding Site on the Hepatitis C Virus NS5B RNA Polymerase Enzyme
Q24675068Crystallographic analysis of CD40 recognition and signaling by human TRAF2
Q27764929Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha
Q27622027Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha
Q27618500Crystallographic and functional studies of very short patch repair endonuclease
Q27636675Crystallographic and modeling studies of RNase III suggest a mechanism for double-stranded RNA cleavage
Q27629024Crystallographic evidence for substrate-assisted catalysis in a bacterial beta-hexosaminidase
Q41043872Crystallographic studies of elongation factor G.
Q27641654Crystallographic studies on Ascaris suum NAD-malic enzyme bound to reduced cofactor and identification of an effector site
Q27638966Crystals of peptide deformylase from Plasmodium falciparum reveal critical characteristics of the active site for drug design
Q27641434CtBP/BARS: a dual-function protein involved in transcription co-repression and Golgi membrane fission
Q34513432Curling of flap tips in HIV-1 protease as a mechanism for substrate entry and tolerance of drug resistance
Q40841563Current insights into the "antiphospholipid" syndrome: clinical, immunological, and molecular aspects
Q43902321Cutinase-peptide fusions in thermoseparating aqueous two-phase systems. Prediction of partitioning and enhanced tag efficiency by detergent addition
Q43832463Cysteine proteinases from distinct cellular compartments are recruited to phagocytic vesicles by Entamoeba histolytica
Q46944628Cytochrome P450 Cyp4x1 is a major P450 protein in mouse brain
Q27640625Cytochrome c nitrite reductase from Desulfovibrio desulfuricans ATCC 27774. The relevance of the two calcium sites in the structure of the catalytic subunit (NrfA)
Q28771384DAPK catalytic activity in the hippocampus increases during the recovery phase in an animal model of brain hypoxic-ischemic injury
Q37148548DBSI: DNA-binding site identifier.
Q41675411DNA bending by EcoRI DNA methyltransferase accelerates base flipping but compromises specificity
Q36281972DNA inhibits catalysis by the carboxyltransferase subunit of acetyl-CoA carboxylase: implications for active site communication.
Q34537672DNA polymerase beta.
Q74164952DNA polymerases on the move
Q33968785DNA recognition by the herpes simplex virus transactivator VP16: a novel DNA-binding structure.
Q31452230DNA structure and aspartate 276 influence nucleotide binding to human DNA polymerase beta. Implication for the identity of the rate-limiting conformational change
Q34837310Death-associated protein kinase as a potential therapeutic target
Q43621565Deciphering RNA recognition: aminoglycoside binding to the hammerhead ribozyme
Q43967340Deciphering the action of aromatic effectors on the prokaryotic enhancer-binding protein XylR: a structural model of its N-terminal domain.
Q74343225Decreased thermodynamic stability as a crucial factor for familial amyloidotic polyneuropathy
Q27734070Deep penetration of an alpha-helix into a widened RNA major groove in the HIV-1 rev peptide-RNA aptamer complex
Q27640178Deep trefoil knot implicated in RNA binding found in an archaebacterial protein
Q44509215Defective expression of Bruton's tyrosine kinase in acute lymphoblastic leukemia
Q27934111Defining protein interactions with yeast actin in vivo
Q27621942Deleterious effects of β-branched residues in the S1 specificity pocket of Streptomyces griseus proteinase B (SGPB): Crystal structures of the turkey ovomucoid third domain variants Ile18I, Val18I, Thr18I, and Ser18I in complex with SGPB
Q38327973Dengue virus NS3 serine protease. Crystal structure and insights into interaction of the active site with substrates by molecular modeling and structural analysis of mutational effects
Q27642434Design and Structure-Based Study of New Potential FKBP12 Inhibitors
Q36808670Design of fast enzymes by optimizing interaction potential in active site.
Q27664292Design, Synthesis, and Crystal Structures of 6-Alkylidene-2′-Substituted Penicillanic Acid Sulfones as Potent Inhibitors of Acinetobacter baumannii OXA-24 Carbapenemase
Q24550750Designed to be stable: crystal structure of a consensus ankyrin repeat protein
Q34075592Designed to penetrate: time-resolved interaction of single antibiotic molecules with bacterial pores
Q47786065Detailed NMR analysis of the heme-protein interactions in component IV Glycera dibranchiata monomeric hemoglobin-CO.
Q44559371Determinants of binding affinity and specificity for the interaction of TEM-1 and SME-1 beta-lactamase with beta-lactamase inhibitory protein
Q27641058Determinants of enzymatic specificity in the Cys-Met-metabolism PLP-dependent enzymes family: crystal structure of cystathionine gamma-lyase from yeast and intrafamiliar structure comparison
Q47769787Determination of Collision Cross Sections Using a Fourier Transform Electrostatic Linear Ion Trap Mass Spectrometer
Q81596434Development of E3-substrate (MDM2-p53)-binding inhibitors: structural aspects
Q33299645Development of peptide mimics of a protective epitope of Vibrio cholerae Ogawa O-antigen and investigation of the structural basis of peptide mimicry
Q34179284Differences in electrostatic properties at antibody-antigen binding sites: implications for specificity and cross-reactivity
Q39593941Differences in the mannose oligomer specificities of the closely related lectins from Galanthus nivalis and Zea mays strongly determine their eventual anti-HIV activity
Q41845211Differences in the roles of conserved glutamic acid residues in the active site of human class 3 and class 2 aldehyde dehydrogenases
Q57235371Differences in the substrate binding sites of murine and human proteinase 3 and neutrophil elastase
Q28344738Different Smad2 partners bind a common hydrophobic pocket in Smad2 via a defined proline-rich motif
Q51657375Different interaction modes of two cytochrome-c oxidase soluble CuA fragments with their substrates.
Q28637692Differential activation of acute phase response factor/Stat3 and Stat1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. II. Src homology SH2 domains define the specificity of stat factor activation
Q28776435Differential binding to HLA-C of p50-activating and p58-inhibitory natural killer cell receptors
Q24324340Dimeric association and segmental variability in the structure of human CD4
Q27628357Dimeric structure of the coxsackievirus and adenovirus receptor D1 domain at 1.7 A resolution
Q43000739Direct interactions between molecular chaperones heat-shock protein (Hsp) 70 and Hsp40: yeast Hsp70 Ssa1 binds the extreme C-terminal region of yeast Hsp40 Sis1.
Q38269335Direct proton magnetic resonance determination of the pKa of the active center histidine in thiolsubtilisin
Q42155996Directed evolution and structural analysis of N-carbamoyl-D-amino acid amidohydrolase provide insights into recombinant protein solubility in Escherichia coli
Q34232358Directed evolution of Streptomyces clavuligerus deacetoxycephalosporin C synthase for enhancement of penicillin G expansion
Q56900591Directed evolution of substrate-optimized GroEL/S chaperonins
Q28118969Disruption of dimerization and substrate phosphorylation inhibit factor inhibiting hypoxia-inducible factor (FIH) activity
Q44632584Dissecting subunit interfaces in homodimeric proteins
Q24338368Dissecting the N-terminal myosin binding site of human cardiac myosin-binding protein C. Structure and myosin binding of domain C2
Q43508477Dissection of a nuclear localization signal
Q43733979Dissociation and aggregation of calpain in the presence of calcium
Q27642991Distant structural homology leads to the functional characterization of an archaeal PIN domain as an exonuclease
Q24302174Distinct molecular mechanism for initiating TRAF6 signalling
Q27641994Distinct requirements for heparin and alpha-dystroglycan binding revealed by structure-based mutagenesis of the laminin alpha2 LG4-LG5 domain pair
Q31139833Disulfide pairings and secondary structure of porcine β‐microseminoprotein
Q42480603Diverse biochemical properties of Shp2 mutants. Implications for disease phenotypes
Q44408568Diversity in the SH2 domain family phosphotyrosyl peptide binding site
Q44450154Docking and electron transfer studies between rubredoxin and rubredoxin:oxygen oxidoreductase
Q42164220Docking multiple conformations of a flexible ligand into a protein binding site using NMR restraints
Q57275259Domain One of the High Affinity IgE Receptor, FcεRI, Regulates Binding to IgE through Its Interface with Domain Two
Q46586694Domain assembly, surface accessibility and sequence conservation in full length HIV-1 Nef.
Q54569197Domain organization of Escherichia coli transcript cleavage factors GreA and GreB.
Q28578082Domain swapping in the low-similarity isomerase/hydratase superfamily: the crystal structure of rat mitochondrial Delta3, Delta2-enoyl-CoA isomerase
Q44829594Double-sided ubiquitin binding of Hrs-UIM in endosomal protein sorting
Q24297105Downstream regulator TANK binds to the CD40 recognition site on TRAF3
Q27629798Dramatic structural and thermodynamic consequences of repacking a protein's hydrophobic core
Q39856385Dry molten globule intermediates and the mechanism of protein unfolding
Q27649259Dual GPCR and GAG mimicry by the M3 chemokine decoy receptor
Q27618629Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs
Q24630138Dual epitope recognition by the VASP EVH1 domain modulates polyproline ligand specificity and binding affinity
Q27642989Dual, HLA-B27 Subtype-dependent Conformation of a Self-peptide
Q60958475Duplication and Diversification of - A Case Study in the Papaveraceae
Q34302168Dynamic evolution of the human immunodeficiency virus type 1 pathogenic factor, Nef.
Q34193021Dynamic of beta(2)-microglobulin fibril formation and reabsorption: the role of proteolysis
Q27631350Dynamic properties of the Ras switch I region and its importance for binding to effectors
Q42563954Dynamic surface activity by folding and unfolding an amphiphilic alpha-helix
Q27639619E. coli dihydroorotate dehydrogenase reveals structural and functional distinctions between different classes of dihydroorotate dehydrogenases
Q24296900EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization
Q44144522EGF domain II of protein Pb28 from Plasmodium berghei interacts with monoclonal transmission blocking antibody 13.1.
Q43832072Editors and editing of anti-DNA receptors.
Q27642659Effect of N-terminal and Met23 mutations on the structure and dynamics of onconase
Q74560841Effect of charge interactions on the carboxylate vibrational stretching frequency in c-type cytochromes investigated by continuum electrostatic calculations and FTIR spectroscopy
Q73822397Effect of ligand binding on the flexibility of dihydrofolate reductase as revealed by compressibility
Q43764048Effect of phospholipid on trichosanthin adsorption at the air-water interface
Q27628384Effector sites in the three-dimensional structure of mammalian sperm beta-acrosin
Q24338397Effects of p47phox C terminus phosphorylations on binding interactions with p40phox and p67phox. Structural and functional comparison of p40phox and p67phox SH3 domains
Q30431602Effects of salt bridges on protein structure and design.
Q40236633Effects on ligand interaction and membrane translocation of the positively charged arginine residues situated along the C1 domain binding cleft in the atypical protein kinase C isoforms
Q30620916Efficient electrostatic solvation model for protein-fragment docking
Q54538029Electron transfer from the Rieske iron-sulfur protein (ISP) to cytochrome f in vitro. Is a guided trajectory of the ISP necessary for competent docking?
Q33803871Electron transfers amongst cytochrome f, plastocyanin and photosystem I: kinetics and mechanisms
Q74847794Electron-proton interactions in terminal oxidases
Q24532908Electrostatic binding of proteins to membranes. Theoretical predictions and experimental results with charybdotoxin and phospholipid vesicles
Q38272342Electrostatic contributions to protein-protein interactions: fast energetic filters for docking and their physical basis
Q34169304Electrostatic contributions to the binding free energy of the lambdacI repressor to DNA.
Q34110570Electrostatic control of the membrane targeting of C2 domains
Q79736686Electrostatic control of the overall shape of calmodulin: numerical calculations
Q34040476Electrostatic coupling between retinal isomerization and the ionization state of Glu-204: a general mechanism for proton release in bacteriorhodopsin
Q43733544Electrostatic effects on the free-energy balance in folding a ribosome-inactivating protein
Q33178780Electrostatic forces involved in orienting Anabaena ferredoxin during binding to Anabaena ferredoxin:NADP+ reductase: site-specific mutagenesis, transient kinetic measurements, and electrostatic surface potentials
Q36281595Electrostatic interactions in the GCN4 leucine zipper: substantial contributions arise from intramolecular interactions enhanced on binding
Q36559762Electrostatic interactions in the reconstitution of an SH2 domain from constituent peptide fragments
Q36737350Electrostatic properties of cowpea chlorotic mottle virus and cucumber mosaic virus capsids
Q42196651Electrostatic properties of cytochrome f: implications for docking with plastocyanin
Q30447412Electrostatic sequestration of PIP2 on phospholipid membranes by basic/aromatic regions of proteins
Q53585575Electrostatically Driven Spatial Patterns in Lipid Membrane Composition
Q57823322Electrostatics in the active site of an alpha-amylase
Q47625563Electrostatics, allostery, and activity of the yeast chorismate mutase
Q34236478Elucidation of a novel extracellular calcium-binding site on metabotropic glutamate receptor 1{alpha} (mGluR1{alpha}) that controls receptor activation.
Q40708038Elucidation of the mode of substrate binding to hydroxynitrile lyase from Hevea brasiliensis.
Q47782025Emerging Concepts in TCR Specificity: Rationalizing and (Maybe) Predicting Outcomes
Q77456869Emerging themes in structural biology of neurotrophic factors
Q36280587Empirical free energy calculation: comparison to calorimetric data
Q27734082Encapsulating an amino acid in a DNA fold
Q79295182Encapsulation Induces Helical Folding of Alkanes
Q24550829Endophilin BAR domain drives membrane curvature by two newly identified structure-based mechanisms
Q34181175Energetic and structural considerations for the mechanism of protein sliding along DNA in the nonspecific BamHI-DNA complex.
Q37521207Energetic basis for selective recognition of T*G mismatched base pairs in DNA by imidazole-rich polyamides
Q74294211Engineering Src family protein kinases with unnatural nucleotide specificity
Q51728522Engineering a thermostable protein with two DNA-binding domains using the hyperthermophile protein Sac7d.
Q27636272Engineering photocycle dynamics. Crystal structures and kinetics of three photoactive yellow protein hinge-bending mutants
Q53665900Engineering soluble proteins for structural genomics.
Q43596202Engineering the pH-optimum of a triglyceride lipase: from predictions based on electrostatic computations to experimental results
Q37192171Enhanced exposure of the CD4-binding site to neutralizing antibodies by structural design of a membrane-anchored human immunodeficiency virus type 1 gp120 domain
Q37340760Enhanced surface hydrophobicity by coupling of surface polarity and topography
Q51990458Enhancement to the RANKPEP resource for the prediction of peptide binding to MHC molecules using profiles.
Q44140859Enhancing oxidative resistance of Agrobacterium radiobacter N-carbamoyl D-amino acid amidohydrolase by engineering solvent-accessible methionine residues
Q27641982Enhancing protein crystallization through precipitant synergy
Q43043432Enthalpic and entropic contributions mediate the role of disulfide bonds on the conformational stability of interleukin-4.
Q27640029Enzymatic and structural analysis of inhibitors designed against Mycobacterium tuberculosis thymidylate kinase. New insights into the phosphoryl transfer mechanism
Q38302248Enzymatic circularization of a malto-octaose linear chain studied by stochastic reaction path calculations on cyclodextrin glycosyltransferase
Q33951781Enzyme-like proteins by computational design
Q44588572Enzymic, phylogenetic, and structural characterization of the unusual papain-like protease domain of Plasmodium falciparum SERA5.
Q56969976Epistructural Selectivity Filters for Molecular Targeted Therapy
Q79328145Epitope mapping of pneumococcal surface protein A of strain Rx1 using monoclonal antibodies and molecular structure modelling
Q24669673Epsin 1 undergoes nucleocytosolic shuttling and its eps15 interactor NH(2)-terminal homology (ENTH) domain, structurally similar to Armadillo and HEAT repeats, interacts with the transcription factor promyelocytic leukemia Zn(2)+ finger protein (PLZ
Q36278258Estimation of the maximum change in stability of globular proteins upon mutation of a hydrophobic residue to another of smaller size
Q27748840Eukaryotic RNA polymerase subunit RPB8 is a new relative of the OB family
Q74369894Eukaryotic transcription factors
Q24675628Eukaryotic translation elongation factor 1 gamma contains a glutathione transferase domain--study of a diverse, ancient protein superfamily using motif search and structural modeling
Q42845592Evaluating the energetics of empty cavities and internal mutations in proteins
Q50637695Evaluation of electrostatic interactions.
Q40501290Evidence for domain-specific recognition of SK and Kv channels by MTX and HsTx1 scorpion toxins.
Q30650769Evidence for phosphorylation-dependent conformational changes in methylesterase CheB.
Q40191178Evidence for positive Darwinian selection of Vip gene in Bacillus thuringiensis
Q28369397Evidence that a prominent cavity in the coiled coil of HIV type 1 gp41 is an attractive drug target
Q41278555Evidence that the antigen receptors of cytotoxic T lymphocytes interact with a common recognition pattern on the H-2Kb molecule
Q37866109Evidence that the fosfomycin target Cys115 in UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) is essential for product release
Q27650945Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease
Q27683944Evolution of vitamin B2 biosynthesis: eubacterial RibG and fungal Rib2 deaminases
Q46970709Evolutional design of a hyperactive cysteine- and methionine-free mutant of Escherichia coli dihydrofolate reductase.
Q34694679Experimental and computational probes of the space in a self-assembled capsule
Q77443286Exploration of metal ion binding sites in RNA folds by Brownian-dynamics simulations
Q34169778Exploration of the structural features defining the conduction properties of a synthetic ion channel
Q36277185Exploring icosahedral virus structures with VIPER.
Q30353783Exploring protein interfaces with a general photochemical reagent.
Q43842112Exploring protein-protein interactions by peptide docking protocols
Q27650954Exploring the Limits of Sequence and Structure in a Variant βγ-Crystallin Domain of the Protein Absent in Melanoma-1 (AIM1)
Q49161188Expression analysis of a type S2 EUL-related lectin from rice in Pichia pastoris.
Q35270807Expression of an Mg2+-dependent HIV-1 RNase H construct for drug screening
Q27621927Expression, purification, and structural analysis of the trimeric form of the catalytic domain of the Escherichia coli dihydrolipoamide succinyltransferase
Q28208096Extended disordered proteins: targeting function with less scaffold
Q47926568External and internal electrostatic potentials of cholinesterase models
Q48745177Extracting biomolecule collision cross sections from the high-resolution FT-ICR mass spectral linewidths.
Q60358049Extraction of endoglucanase I (Cel7B) fusion proteins from Trichoderma reesei culture filtrate in a poly(ethylene glycol)–phosphate aqueous two-phase system
Q27640173F-actin-like filaments formed by plasmid segregation protein ParM
Q43560122Factor IXa:factor VIIIa interaction. helix 330-338 of factor ixa interacts with residues 558-565 and spatially adjacent regions of the a2 subunit of factor VIIIa
Q41808182Factors influencing accuracy of computer-built models: a study based on leucine zipper GCN4 structure
Q37572290Family shuffling of expandase genes to enhance substrate specificity for penicillin G.
Q37345021Fast, adaptive evolution at a bacterial host-resistance locus: the PFam54 gene array in Borrelia burgdorferi
Q28592892Fate of two mast cell tryptases in V3 mastocytosis and normal BALB/c mice undergoing passive systemic anaphylaxis: prolonged retention of exocytosed mMCP-6 in connective tissues, and rapid accumulation of enzymatically active mMCP-7 in the blood
Q24602743Ferredoxin:NADPH oxidoreductase is recruited to thylakoids by binding to a polyproline type II helix in a pH-dependent manner
Q38324440Fibrillin-1 interactions with heparin. Implications for microfibril and elastic fiber assembly
Q74460969Filling a cavity dramatically increases pressure stability of the c-Myb R2 subdomain
Q37277057Finding and characterizing tunnels in macromolecules with application to ion channels and pores.
Q35212106Flavivirus RNA cap methyltransferase: structure, function, and inhibition
Q27733386Flexibility is a likely determinant of binding specificity in the case of ileal lipid binding protein
Q28623540Flexibility of the NSAID binding site in the structure of human cyclooxygenase-2
Q27620999Flexibility, conformational diversity and two dimerization modes in complexes of ribosomal protein L12
Q27641656Flexible DNA bending in HU-DNA cocrystal structures
Q27636815Flipping a genetic switch by subunit exchange
Q27671696Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing
Q27766044Formation of an amino-acid-binding pocket through adaptive zippering-up of a large DNA hairpin loop
Q50207107Free Energy, Enthalpy and Entropy from Implicit Solvent End-Point Simulations.
Q34176045Free energy decomposition of protein-protein interactions.
Q38329838Free energy determinants of binding the rRNA substrate and small ligands to ricin A-chain
Q34017644Free-energy determinants of alpha-helix insertion into lipid bilayers
Q73856639Full window stereo
Q27765710Function from structure? The crystal structure of human phosphatidylethanolamine-binding protein suggests a role in membrane signal transduction
Q42932424Function of the 90-loop (Thr90-Glu100) region of staphylokinase in plasminogen activation probed through site-directed mutagenesis and loop deletion
Q27648950Functional Specificity of a Hox Protein Mediated by the Recognition of Minor Groove Structure
Q58813365Functional analyses and molecular modeling of two c-Kit mutations responsible for imatinib secondary resistance in GIST patients
Q33413089Functional analysis and molecular dynamics simulation of LOX-1 K167N polymorphism reveal alteration of receptor activity
Q37696831Functional analysis of mutant neurotrophins deficient in low-affinity binding reveals a role for p75LNGFR in NT-4 signalling.
Q30430241Functional analysis of the amino-terminal 8-kDa domain of DNA polymerase beta as revealed by site-directed mutagenesis. DNA binding and 5'-deoxyribose phosphate lyase activities
Q53786418Functional and mutational analyses of an omega-class glutathione S-transferase (GSTO2) that is required for reducing oxidative damage in Apis cerana cerana.
Q27626749Functional aspects of the heme bound hemophore HasA by structural analysis of various crystal forms
Q42050744Functional characterization and structural modelling of late gene expression factor 4 from Bombyx mori nucleopolyhedrovirus
Q36342135Functional characterization of the heterodimeric sweet taste receptor T1R2 and T1R3 from a New World monkey species (squirrel monkey) and its response to sweet-tasting proteins
Q44915751Functional constraints of alcohol dehydrogenase (ADH) of tephritidae and relationships with other Dipteran species
Q46985613Functional dissection of naturally occurring amino acid substitutions in eIF4E that confers recessive potyvirus resistance in plants
Q53173230Functional diversity of PH domains: an exhaustive modelling study
Q44924265Functional domains of Brevibacillus thermoruber lon protease for oligomerization and DNA binding: role of N-terminal and sensor and substrate discrimination domains.
Q27634125Functional equality in the absence of structural similarity: an added dimension to molecular mimicry
Q30322978Functional evaluation of tumour-specific variants of p16INK4a/CDKN2A: correlation with protein structure information.
Q28469139Functional impact of missense variants in BRCA1 predicted by supervised learning
Q39592139Functional implications of the human T-lymphotropic virus type 1 transmembrane glycoprotein helical hairpin structure
Q27641376Functional insights revealed by the crystal structures of Escherichia coli glucose-1-phosphatase
Q44753655Functional properties of soybean nodulin 26 from a comparative three-dimensional model
Q45175188Functional properties of the alternative NADH:ubiquinone oxidoreductase from E. coli through comparative 3-D modelling
Q34195463Functional sites and evolutionary connections of acylhomoserine lactone synthases
Q43018390Functionally important substructures of circadian clock protein KaiB in a unique tetramer complex.
Q27644231G-quadruplex recognition by quinacridines: a SAR, NMR, and biological study
Q27650491GIT1 Paxillin-binding Domain Is a Four-helix Bundle, and It Binds to Both Paxillin LD2 and LD4 Motifs
Q33196267GRASP2: visualization, surface properties, and electrostatics of macromolecular structures and sequences
Q41772598GRASS: a server for the graphical representation and analysis of structures
Q27639901GW domains of the Listeria monocytogenes invasion protein InlB are SH3-like and mediate binding to host ligands
Q34572683Gal80 dimerization and the yeast GAL gene switch
Q46498915Gas behavior in self-assembled capsules
Q42512845Gbeta residues that do not interact with Galpha underlie agonist-independent activity of K+ channels
Q35108599Gecko iota-crystallin: how cellular retinol-binding protein became an eye lens ultraviolet filter
Q27639621Gene sequence and the 1.8 A crystal structure of the tungsten-containing formate dehydrogenase from Desulfovibrio gigas
Q34616812Genetic analysis of the interface between Cdc42p and the CRIB domain of Ste20p in Saccharomyces cerevisiae
Q38303077Genetically engineered peptide fusions for improved protein partitioning in aqueous two-phase systems. Effect of fusion localization on endoglucanase I of Trichoderma reesei
Q42029216Genome segment 6 of Antheraea mylitta cypovirus encodes a structural protein with ATPase activity.
Q27934605Genome-wide analysis of membrane targeting by S. cerevisiae pleckstrin homology domains
Q47233097Genome-wide analysis of restriction-modification system in unicellular and filamentous cyanobacteria
Q51556913Geometric Detection Algorithms for Cavities on Protein Surfaces in Molecular Graphics: A Survey.
Q43971225Geometric isomers of a photoactivable general anesthetic delineate a binding site on adenylate kinase
Q27734656Giant protein kinases: domain interactions and structural basis of autoregulation
Q27735026Glutaconate CoA-transferase from Acidaminococcus fermentans: the crystal structure reveals homology with other CoA-transferases
Q27641127Glutathione reductase of the malarial parasite Plasmodium falciparum: crystal structure and inhibitor development
Q27634919Glycerol dehydrogenase. structure, specificity, and mechanism of a family III polyol dehydrogenase
Q39758878Glycoprotein hormone receptors: determinants in leucine-rich repeats responsible for ligand specificity
Q27638076H5 avian and H9 swine influenza virus haemagglutinin structures: possible origin of influenza subtypes
Q28270353HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations
Q30175254HIV-2 and SIV nef proteins target different Src family SH3 domains than does HIV-1 Nef because of a triple amino acid substitution
Q27621039Helianthus tuberosus lectin reveals a widespread scaffold for mannose-binding lectins
Q35688410Helical kink and channel behaviour: a comparative study with the peptaibols alamethicin, trichotoxin and antiamoebin
Q54576540Helicase-contrahelicase interaction and the mechanism of termination of DNA replication.
Q30943861Heme ligation and conformational plasticity in the isolated c domain of cytochrome cd1 nitrite reductase
Q57983484Heparin-binding protein (HBP/CAP37): A missing link in neutrophil-evoked alteration of vascular permeability
Q27649238Heparin-induced cis- and trans-Dimerization Modes of the Thrombospondin-1 N-terminal Domain
Q27634177Herpes simplex virus glycoprotein D bound to the human receptor HveA
Q37460020Heterodimerization of the sialidase NEU1 with the chaperone protective protein/cathepsin A prevents its premature oligomerization
Q34161698Heterologous expression and characterization of mouse spermine oxidase
Q45091600Hexameric assembly of the bifunctional methylerythritol 2,4-cyclodiphosphate synthase and protein-protein associations in the deoxy-xylulose-dependent pathway of isoprenoid precursor biosynthesis
Q52038041High pressure NMR reveals that apomyoglobin is an equilibrium mixture from the native to the unfolded.
Q27641278High resolution X-ray structure of potent anti-HIV pokeweed antiviral protein-III
Q27639982High resolution crystal structures of Siglec-7. Insights into ligand specificity in the Siglec family
Q27640208High resolution structure, stability, and synaptotagmin binding of a truncated neuronal SNARE complex
Q27621554High resolution x-ray analysis of two mutants of a curaremimetic snake toxin
Q28257550High-affinity binders selected from designed ankyrin repeat protein libraries
Q43137326High-pressure 1H NMR study of pressure-induced structural changes in the heme environments of metcyanomyoglobins
Q43058002High-quality homology models derived from NMR and X-ray structures of E. coli proteins YgdK and Suf E suggest that all members of the YgdK/Suf E protein family are enhancers of cysteine desulfurases
Q34302070High-resolution molecular and antigen structure of the VP8* core of a sialic acid-independent human rotavirus strain.
Q72328408High-resolution solution structure of siamycin II: novel amphipathic character of a 21-residue peptide that inhibits HIV fusion
Q27641428High-resolution structure of RNase P protein from Thermotoga maritima
Q27642248High-resolution structure of the E.coli RecQ helicase catalytic core
Q34120510High-resolution structure of the catalytic region of MICAL (molecule interacting with CasL), a multidomain flavoenzyme-signaling molecule
Q27639493High-resolution structure of the pleckstrin homology domain of protein kinase b/akt bound to phosphatidylinositol (3,4,5)-trisphosphate
Q30387975High-throughput computational structure-based characterization of protein families: START domains and implications for structural genomics
Q33224737Histone structure and nucleosome stability
Q34743119Homology model building of the HMG-1 box structural domain
Q57135421Homology model of a novel xylanase: molecular basis for high-thermostability and alkaline stability
Q54565025Homology modeling of adenylosuccinate synthetase from Saccharomyces cerevisiae reveals a possible binding region for single-stranded ARS sequences.
Q34169791Homology modeling of cephalopod lens S-crystallin: a natural mutant of sigma-class glutathione transferase with diminished endogenous activity
Q74707474Homology modeling of the cellulose-binding domain of a pollen allergen from rye grass: structural basis for the cellulose recognition and associated allergenic properties
Q77622447Homology modeling of the receptor binding domain of human thrombopoietin
Q73501704Homology modelling of an antimicrobial protein, Ace-AMP1, from lipid transfer protein structures
Q27640397Homotetrameric structure of the SNAP-23 N-terminal coiled-coil domain
Q30165044How SH3 domains recognize proline
Q47406110How a G protein binds a membrane
Q27733377How coenzyme B12 radicals are generated: the crystal structure of methylmalonyl-coenzyme A mutase at 2 A resolution
Q31878227How do lipases and esterases work: the electrostatic contribution
Q90389143How internal cavities destabilize a protein
Q33716832Hsp70 mutant proteins modulate additional apoptotic pathways and improve cell survival
Q27622024Human glucose-6-phosphate dehydrogenase: the crystal structure reveals a structural NADP(+) molecule and provides insights into enzyme deficiency
Q22008497Human phosphoinositide 3-kinase C2beta, the role of calcium and the C2 domain in enzyme activity
Q27620027Human replication protein A: global fold of the N-terminal RPA-70 domain reveals a basic cleft and flexible C-terminal linker
Q27749281Human theta class glutathione transferase: the crystal structure reveals a sulfate-binding pocket within a buried active site
Q30328729Human tryptase epsilon (PRSS22), a new member of the chromosome 16p13.3 family of human serine proteases expressed in airway epithelial cells.
Q27634630Hyaluronan binding and degradation by Streptococcus agalactiae hyaluronate lyase
Q33229875Hydration changes in the association of Hoechst 33258 with DNA.
Q36739638Hydration sites in purine.purine.pyrimidine and pyrimidine.purine.pyrimidine DNA triplexes in aqueous solution
Q44070291Hydrazones of 1,2-benzisothiazole hydrazides: synthesis, antimicrobial activity and QSAR investigations.
Q35148078Hydride transfer catalysed by Escherichia coli and Bacillus subtilis dihydrofolate reductase: coupled motions and distal mutations
Q36640717Hydrogen-bonding classes in proteins and their contribution to the unfolding reaction
Q42019968Hydrolysis of (1,4)-beta-D-mannans in barley (Hordeum vulgare L.) is mediated by the concerted action of (1,4)-beta-D-mannan endohydrolase and beta-D-mannosidase
Q57296153Hydrophobic alkyl chains substituted to the 8-position of cyclic nucleotides enhance activation of CNG and HCN channels by an intricate enthalpy - entropy compensation
Q34170112Hydrophobic hydration of amphipathic peptides
Q42845402Hydrophobic regions on protein surfaces. Derivation of the solvation energy from their area distribution in crystallographic protein structures
Q43671277Hydrophobicity and functionality maps of farnesyltransferase
Q34014544Hydrophobicity: is LogP(o/w) more than the sum of its parts?
Q33961244Hydroxamido vanadates: aqueous chemistry and function in protein tyrosine phosphatases and cell cultures
Q28203641Hyperthermophilic enzymes: sources, uses, and molecular mechanisms for thermostability
Q24291729IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor binding
Q27628168Identification and analysis of the acyl carrier protein (ACP) docking site on beta-ketoacyl-ACP synthase III
Q34624323Identification and mapping of small-molecule binding sites in proteins: computational tools for structure-based drug design
Q33647388Identification and structural characterization of FYVE domain-containing proteins of Arabidopsis thaliana
Q27639824Identification and structure of the anti-sigma factor-binding domain of the disulphide-stress regulated sigma factor sigma(R) from Streptomyces coelicolor
Q43603105Identification of Significant residues for homoallylic substrate binding of Micrococcus luteus B-P 26 undecaprenyl diphosphate synthase
Q74763052Identification of a basic surface area of the FADD death effector domain critical for apoptotic signaling
Q44964533Identification of a general anesthetic binding site in the diacylglycerol-binding domain of protein kinase Cdelta
Q27643681Identification of a glycosaminoglycan binding region of the alpha C protein that mediates entry of group B Streptococci into host cells
Q73204426Identification of a selectivity determinant for inhibition of tumor necrosis factor-alpha converting enzyme by comparative modeling
Q36789560Identification of a structural determinant for resistance to beta-lactam antibiotics in Gram-positive bacteria
Q39756934Identification of amino acid residues in the capsid proteins of adeno-associated virus type 2 that contribute to heparan sulfate proteoglycan binding
Q34127067Identification of amino acid residues of anthrax protective antigen involved in binding with lethal factor
Q24652387Identification of amino acids essential for the antiangiogenic activity of tumstatin and its use in combination antitumor activity
Q41831899Identification of critical residues in the colicin E9 DNase binding region of the Im9 protein
Q37346360Identification of important chemical groups of the hut mRNA for HutP interactions that regulate the hut operon in Bacillus subtilis.
Q59068045Identification of in vivo substrates of the chaperonin GroEL
Q31959722Identification of protein-protein interfaces by decreased amide proton solvent accessibility
Q40863570Identification of residues critical for toxicity in Clostridium perfringens phospholipase C, the key toxin in gas gangrene.
Q73763944Identification of residues in the TPR domain of Ssn6 responsible for interaction with the Tup1 protein
Q46796105Identification of residues surrounding the active site of type A botulinum neurotoxin important for substrate recognition and catalytic activity
Q27472909Identification of the hepatitis C virus E2 glycoprotein binding site on the large extracellular loop of CD81
Q24537239Identification of the ice-binding surface on a type III antifreeze protein with a "flatness function" algorithm
Q30840326Identification of the peptide-binding site in the heat shock chaperone/tumor rejection antigen gp96 (Grp94).
Q24656051Identification of xenoestrogens in food additives by an integrated in silico and in vitro approach
Q22010983Identification, characterization and crystal structure analysis of the human spliceosomal U5 snRNP-specific 15 kD protein
Q27622324Identification, characterization, and crystal structure of the Omega class glutathione transferases
Q27648926Identification, structure and mode of action of a new regulator of the Helicobacter pylori HP0525 ATPase
Q41346923Immunochemical mapping of gonadotropins
Q34524562Immunophysical properties and prediction of activities for vaccinia virus complement control protein and smallpox inhibitor of complement enzymes using molecular dynamics and electrostatics
Q41005847Impaired MHC class I (H-2Dd)-mediated protection against Ly-49A+ NK cells after amino acid substitutions in the antigen binding cleft
Q27677138Imperfect interface of Beclin1 coiled-coil domain regulates homodimer and heterodimer formation with Atg14L and UVRAG
Q44589119Implicit solvent model estimates of the stability of model structures of the alamethicin channel
Q28346274Implicit solvent model studies of the interactions of the influenza hemagglutinin fusion peptide with lipid bilayers
Q47796595Improved protein-ligand binding affinity prediction by using a curvature-dependent surface-area model
Q33965235In-depth mutational analysis of the promyelocytic leukemia zinc finger BTB/POZ domain reveals motifs and residues required for biological and transcriptional functions
Q36412093Inactivation and secondary structure in the D4/S4-5 region of the SkM1 sodium channel
Q35968386Incomplete protein packing as a selectivity filter in drug design
Q35728727Inefficient proofreading and biased error rates during inaccurate DNA synthesis by a mutant derivative of Saccharomyces cerevisiae DNA polymerase delta.
Q41624686Infectious bursal disease virus capsid assembly and maturation by structural rearrangements of a transient molecular switch
Q43791053Inhibition of Saccharomyces cerevisiae phosphomannose isomerase by the NO-donor S-nitroso-acetyl-penicillamine
Q27619600Inhibition of human immunodeficiency virus type 1 infectivity by the gp41 core: role of a conserved hydrophobic cavity in membrane fusion
Q46977401Inhibition of polyamine and spermine oxidases by polyamine analogues.
Q27620967Inhibition of the HIV-1 and HIV-2 proteases by a monoclonal antibody
Q44529216Inhibition of the norepinephrine transporter by the venom peptide chi-MrIA. Site of action, Na+ dependence, and structure-activity relationship
Q73396510Initiation of spectrin dimerization involves complementary electrostatic interactions between paired triple-helical bundles
Q58462587Insertions into the β3-β4 Hairpin Loop of HIV-1 Reverse Transcriptase Reveal a Role for Fingers Subdomain in Processive Polymerization
Q27654167Insight into the protein and solvent contributions to the reduction potentials of [4Fe-4S]2+/+ clusters: crystal structures of the Allochromatium vinosum ferredoxin variants C57A and V13G and the homologous Escherichia coli ferredoxin
Q29617624Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex
Q30176177Insights into Src kinase functions: structural comparisons
Q27633189Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains
Q34073403Insights into programmed cell death through structural biology
Q27733394Insights into specificity of cleavage and mechanism of cell entry from the crystal structure of the highly specific Aspergillus ribotoxin, restrictocin
Q27640121Insights into substrate binding and catalytic mechanism of human tyrosyl-DNA phosphodiesterase (Tdp1) from vanadate and tungstate-inhibited structures
Q27641128Insights into the catalytic mechanism of cofactor-independent phosphoglycerate mutase from X-ray crystallography, simulated dynamics and molecular modeling
Q27628438Insights into the molecular basis of leukocyte tethering and rolling revealed by structures of P- and E-selectin bound to SLe(X) and PSGL-1
Q44512599Insights into the regioselectivity and RNA-binding affinity of HIV-1 nucleocapsid protein from linear-scaling quantum methods
Q28609780Insights into the structure, mechanism, and regulation of scavenger mRNA decapping activity
Q31167286Interaction energies and dynamics of acid-base pairs isolated in cavitands.
Q33574540Interaction of the Hsp70 molecular chaperone, DnaK, with its cochaperone DnaJ.
Q27626679Interaction of the factor XIII activation peptide with alpha -thrombin. Crystal structure of its enzyme-substrate analog complex
Q30885023Interactions of the M2delta segment of the acetylcholine receptor with lipid bilayers: a continuum-solvent model study
Q24644861Interatomic potentials and solvation parameters from protein engineering data for buried residues
Q43818583Interdomain interactions in hinge-bending transitions
Q77210983Internal and overall motions of the translation factor eIF4E: cap binding and insertion in a CHAPS detergent micelle
Q34587520Intragenic suppression of Gal3C interaction with Gal80 in the Saccharomyces cerevisiae GAL gene switch
Q24645338Intrasteric control of AMPK via the gamma1 subunit AMP allosteric regulatory site
Q42062188Intrinsic resistance to aminoglycosides in Enterococcus faecium is conferred by the 16S rRNA m5C1404-specific methyltransferase EfmM
Q41463542Intrinsic selectivity in binding of matrix metalloproteinase-7 to differently charged lipid membranes
Q37893583Intrinsically unstructured proteins and neurodegenerative diseases: conformational promiscuity at its best
Q47448190Investigating the role of the little finger domain of Y-family DNA polymerases in low fidelity synthesis and translesion replication.
Q43690396Investigation of the functional role of active site loop II in a hypoxanthine phosphoribosyltransferase
Q38292513Involvement of a nine-residue loop of streptokinase in the generation of macromolecular substrate specificity by the activator complex through interaction with substrate kringle domains
Q51376657Ion collision cross section analyses in quadrupole ion traps using the filter diagonalization method: a theoretical study.
Q51554018Ion collision cross section measurements in Fourier transform-based mass analyzers.
Q28353894Is there a conserved interaction between cardiolipin and the type II bacterial reaction center?
Q34198808Isolation and characterization of a cone snail protease with homology to CRISP proteins of the pathogenesis-related protein superfamily
Q24562014JavaProtein Dossier: a novel web-based data visualization tool for comprehensive analysis of protein structure
Q38324922Junctional adhesion molecule a serves as a receptor for prototype and field-isolate strains of mammalian reovirus
Q41318459Just add water! The effect of water on the specificity of protein-ligand binding sites and its potential application to drug design
Q44607660Key residues responsible for acyl carrier protein and beta-ketoacyl-acyl carrier protein reductase (FabG) interaction
Q36846802Kinetic and structural insight into the mechanism of BphD, a C-C bond hydrolase from the biphenyl degradation pathway.
Q37687621Kinetic evidence for a two-stage mechanism of protein denaturation by guanidinium chloride
Q34174497Kinetics of association of anti-lysozyme monoclonal antibody D44.1 and hen-egg lysozyme
Q73813727Kinetics of interaction of the myristoylated alanine-rich C kinase substrate, membranes, and calmodulin
Q44134061L23 protein functions as a chaperone docking site on the ribosome
Q39934984LC-MS/MS of permethylated N-glycans derived from model and human blood serum glycoproteins
Q30362756Laboratory evolution of one disulfide isomerase to resemble another
Q34573829Lactoferrin and transferrin: functional variations on a common structural framework
Q24654088Large-scale protein structure modeling of the Saccharomyces cerevisiae genome
Q41290982Lateral pressure in membranes
Q27640887Leads for development of new naphthalenesulfonate derivatives with enhanced antiangiogenic activity: crystal structure of acidic fibroblast growth factor in complex with 5-amino-2-naphthalene sulfonate
Q74584643Leadzyme
Q28576042Lectin control of protein folding and sorting in the secretory pathway
Q34066279Legume lectin structure.
Q27641298Leishmania mexicana glycerol-3-phosphate dehydrogenase showed conformational changes upon binding a bi-substrate adduct
Q28533958Ligand pose and orientational sampling in molecular docking
Q30175366Ligand recognition by SH3 and WW domains: the role of N-alkylation in PPII helices
Q27766375Ligand size is a major determinant of specificity in periplasmic oxyanion-binding proteins: the 1.2 A resolution crystal structure of Azotobacter vinelandii ModA
Q44505348Light adaptation through phosphoinositide-regulated translocation of Drosophila visual arrestin
Q71798182Light-Harvesting Complex: Rings of light
Q73892591Limited plasticity in the recognition of peptide epitope variants by an alloreactive CTL clone correlates directly with conservation of critical residues and inversely with peptide length
Q64926823Limits in accuracy and a strategy of RNA structure prediction using experimental information.
Q27732844Lipase activation by nonionic detergents. The crystal structure of the porcine lipase-colipase-tetraethylene glycol monooctyl ether complex
Q36880662Lipid-induced conformation of substance P.
Q35574706Long dynamics simulations of proteins using atomistic force fields and a continuum representation of solvent effects: calculation of structural and dynamic properties
Q43833668Loss of DNA polymerase beta stacking interactions with templating purines, but not pyrimidines, alters catalytic efficiency and fidelity.
Q33541995Lysine 49 phospholipase A2 proteins
Q41792401Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway.
Q24535678Lysosomal cysteine proteases: facts and opportunities
Q24323388MAD analysis of FHIT, a putative human tumor suppressor from the HIT protein family
Q77521416MARCKS, membranes, and calmodulin: kinetics of their interaction
Q33852576MENT, a heterochromatin protein that mediates higher order chromatin folding, is a new serpin family member
Q52033384MIAX: a new paradigm for modeling biomacromolecular interactions and complex formation in condensed phases.
Q43020662MTH187 from Methanobacterium thermoautotrophicum has three HEAT-like repeats
Q31085066Macromolecular recognition in the Protein Data Bank
Q42264257Macromolecular solvation energies derived from small molecule crystal morphology
Q27633043Macrophage migration inhibitory factor of the parasitic nematode Trichinella spiralis
Q73797172Major changes in the kinetic mechanism of AMP inhibition and AMP cooperativity attend the mutation of Arg49 in fructose-1,6-bisphosphatase
Q43982189Major histocompatibility complex recognition by immune receptors: differences among T cell receptor versus antibody interactions with the VSV8/H-2Kb complex
Q27641615Malignant brain tumor repeats: a three-leaved propeller architecture with ligand/peptide binding pockets
Q37002199Mammalian DNA methyltransferases: a structural perspective
Q36281463Mapping cyclic nucleotide-induced conformational changes in cyclicAMP receptor protein by a protein footprinting technique using different chemical proteases
Q34694924Mapping epitopes and antigenicity by site-directed masking
Q41946244Mapping of ligand-binding cavities in proteins
Q38313808Mapping of the 5'-2-deoxyribose-5-phosphate lyase active site in DNA polymerase beta by mass spectrometry
Q33747994Mapping of the detergent-exposed surface of membrane proteins and peptides by 1H solution NMR in detergent: Application to the gramicidin A ion channel
Q47875597Mapping protein-ligand interactions by footprinting, a radical idea
Q28202817Mapping the Galpha13 binding interface of the rgRGS domain of p115RhoGEF
Q28144724Mapping the binding site for the GTP-binding protein Rac-1 on its inhibitor RhoGDI-1
Q34050464Mapping the specific cytoprotective interaction of humanin with the pro-apoptotic protein bid.
Q42562626Matching the crystallographic structure of ribosomal protein S7 to a three-dimensional model of the 16S ribosomal RNA.
Q52027333Mathematical correlations for predicting protein retention times in hydrophobic interaction chromatography.
Q77455726Matrix metalloproteases: variations on a theme
Q57136102Mean-field analysis of protein-protein interactions
Q77338396Measuring hydration changes of proteins in solution: applications of osmotic stress and structure-based calculations
Q27729793Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex
Q24296916Mechanism of XIAP-mediated inhibition of caspase-9
Q78327596Mechanism of action of RNase T. II. A structural and functional model of the enzyme
Q27637335Mechanism of c-Myb-C/EBP beta cooperation from separated sites on a promoter
Q27638934Mechanism of hyaluronan degradation by Streptococcus pneumoniae hyaluronate lyase. Structures of complexes with the substrate
Q45099229Mechanism of membrane binding of the phospholipase D1 PX domain
Q24297334Mechanism of metal activation of human hematopoietic prostaglandin D synthase
Q27640379Mechanism of molecular interactions for tRNA(Val) recognition by valyl-tRNA synthetase.
Q27634545Mechanism of processivity clamp opening by the delta subunit wrench of the clamp loader complex of E. coli DNA polymerase III
Q27635126Mechanism of product chain length determination and the role of a flexible loop in Escherichia coli undecaprenyl-pyrophosphate synthase catalysis
Q27734591Mechanism of ribonuclease inhibition by ribonuclease inhibitor protein based on the crystal structure of its complex with ribonuclease A
Q27636255Mechanism of ubiquitin activation revealed by the structure of a bacterial MoeB-MoaD complex
Q27641433Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
Q44373949Mechanisms of autoinhibition and STI-571/imatinib resistance revealed by mutagenesis of BCR-ABL.
Q27919623Mechanisms of caspase activation and inhibition during apoptosis
Q27653166Mechanistic Insights into the Hydrolysis and Synthesis of Ceramide by Neutral Ceramidase
Q27732211Mechanistic implications from the structure of a catalytic fragment of Moloney murine leukemia virus reverse transcriptase
Q36779921Meiosis-specific failure of cell cycle progression in fission yeast by mutation of a conserved beta-tubulin residue
Q38338321Members of a new group of chitinase-like genes are expressed preferentially in cotton cells with secondary walls
Q47713325Membrane Position Dependency of the pKa and Conductivity of the Protein Ion Channel
Q40388561Membrane association induces a conformational change in the Ebola virus matrix protein
Q40674156Membrane binding mechanisms of the PX domains of NADPH oxidase p40phox and p47phox
Q36755823Membrane localization is critical for activation of the PICK1 BAR domain
Q28204978Membrane targeting of C2 domains of phospholipase C-delta isoforms
Q59576385Membrane-perturbing activity ofViperidae myotoxins: an electrostatic surface potential approach to a puzzling problem
Q51823949Methodology for predicting the separation of proteins by hydrophobic interaction chromatography and its application to a cell extract.
Q45934941Methods for displaying macromolecular structural uncertainty: Application to the globins
Q78364964Microtubule structure at 8 A resolution
Q27625573Mimicry of ice structure by surface hydroxyls and water of a beta-helix antifreeze protein
Q27639095Minor structural changes in a mutated human melanoma antigen correspond to dramatically enhanced stimulation of a CD4+ tumor-infiltrating lymphocyte line
Q27640047Mismatch Repair in Methylated DNA: STRUCTURE AND ACTIVITY OF THE MISMATCH-SPECIFIC THYMINE GLYCOSYLASE DOMAIN OF METHYL-CpG-BINDING PROTEIN MBD4
Q27765326Mode of binding of anti-P-glycoprotein antibody MRK-16 to its antigen. A crystallographic and molecular modeling study
Q64910935Model of full-length HIV-1 integrase complexed with viral DNA as template for anti-HIV drug design.
Q73396552Modeling and alanine scanning mutagenesis studies of recombinant pokeweed antiviral protein
Q35990863Modeling and structure function analysis of the putative anchor site of yeast telomerase
Q57135724Modeling implicit reorganization in continuum descriptions of protein-protein interactions
Q57206181Modeling of nucleotide binding domains of ABC transporter proteins based on a F1-ATPase/recA topology: structural model of the nucleotide binding domains of the cystic fibrosis transmembrane conductance regulator (CFTR)
Q40775373Modeling the interactions of a peptide-major histocompatibility class I ligand with its receptors. I. Recognition by two alpha beta T cell receptors
Q34174481Modeling zymogen protein C.
Q43966532Modeling-based characterization of the elicitor function of amino acid 461 of Cucumber mosaic virus 1a protein in the hypersensitive response
Q33270379Modelling study of dimerization in mammalian defensins
Q27641332Modular architecture of the bacteriophage T7 primase couples RNA primer synthesis to DNA synthesis
Q38089849Modulating drug impact by wrapping target proteins
Q42580560Modulation of Ligand Binding Affinity of Tumorigenic Carbonic Anhydrase XII upon Interaction with Cationic CdTe Quantum Dots
Q27665985Modulation of inhibitory activity of xylanase - α-amylase inhibitor protein (XAIP): binding studies and crystal structure determination of XAIP- II from Scadoxus multiflorus at 1.2 Å resolution
Q46786486Molecular architecture and ligand recognition determinants for T4 RNA ligase
Q27629274Molecular architecture of full-length KcsA: role of cytoplasmic domains in ion permeation and activation gating
Q27631666Molecular basis for regulatory subunit diversity in cAMP-dependent protein kinase: crystal structure of the type II beta regulatory subunit
Q27733423Molecular basis for the binding of SH3 ligands with non-peptide elements identified by combinatorial synthesis
Q37645695Molecular basis for the inhibition of the carboxyltransferase domain of acetyl-coenzyme-A carboxylase by haloxyfop and diclofop.
Q27640251Molecular basis for the recognition of a nonclassical nuclear localization signal by importin beta
Q36688166Molecular basis for the recognition of two structurally different major histocompatibility complex/peptide complexes by a single T-cell receptor
Q27742097Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module
Q44592821Molecular basis of ion selectivity, block, and rectification of the inward rectifier Kir3.1/Kir3.4 K(+) channel
Q27641143Molecular basis of phosphorylation-induced activation of the NADPH oxidase
Q27628932Molecular basis of sequence-specific recognition of pre-ribosomal RNA by nucleolin
Q27639292Molecular basis of sequence-specific single-stranded DNA recognition by KH domains: solution structure of a complex between hnRNP K KH3 and single-stranded DNA
Q27748778Molecular basis of sulfite oxidase deficiency from the structure of sulfite oxidase
Q28484801Molecular basis of the interaction between the flagellar export proteins FliI and FliH from Helicobacter pylori
Q40756579Molecular basis of the specific subcellular localization of the C2-like domain of 5-lipoxygenase
Q34142840Molecular characterization of adeno-associated viruses infecting children
Q33818289Molecular cloning and characterization of a membrane associated NAC family gene, SiNAC from foxtail millet [Setaria italica (L.) P. Beauv].
Q28276388Molecular docking programs successfully predict the binding of a beta-lactamase inhibitory protein to TEM-1 beta-lactamase
Q34351288Molecular dynamics simulation studies of the effect of phosphocitrate on crystal-induced membranolysis
Q39714826Molecular dynamics simulations and CD spectroscopy reveal hydration-induced unfolding of the intrinsically disordered LEA proteins COR15A and COR15B from Arabidopsis thaliana.
Q30332403Molecular dynamics simulations on SDF-1alpha: binding with CXCR4 receptor
Q42151822Molecular dynamics study of non-nucleoside reverse transcriptase inhibitor 4-[[4-[[4-[(E)-2-cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile (TMC278/rilpivirine) aggregates: correlation between amphiphilic properties of the d
Q52306162Molecular dynamics study of phospholipase A2 on a membrane surface.
Q33907301Molecular dynamics study of time-correlated protein domain motions and molecular flexibility: cytochrome P450BM-3
Q36220942Molecular features of interaction between VEGFA and anti-angiogenic drugs used in retinal diseases: a computational approach
Q51641018Molecular mechanics and dynamics of biomolecules using a solvent continuum model.
Q27639367Molecular mechanism for the regulation of human mitochondrial NAD(P)+-dependent malic enzyme by ATP and fumarate
Q27639262Molecular mechanism for the regulation of protein kinase B/Akt by hydrophobic motif phosphorylation
Q24296184Molecular mechanism of lipopeptide presentation by CD1a
Q24553649Molecular mechanism of recruitment of TFIIF- associating RNA polymerase C-terminal domain phosphatase (FCP1) by transcription factor IIF
Q27645967Molecular mechanism of thioredoxin regulation in photosynthetic A2B2-glyceraldehyde-3-phosphate dehydrogenase
Q29617861Molecular mechanisms of caspase regulation during apoptosis
Q55034496Molecular mimicry between the trimeric ectodomain of the transmembrane protein of immunosuppressive lentiviruses (HIV-SIV-FIV) and interleukin 2.
Q37871576Molecular mimicry of an HLA-B27-derived ligand of arthritis-linked subtypes with chlamydial proteins
Q44173736Molecular model of cyclin-dependent kinase 5 complexed with roscovitine
Q44041043Molecular model of shikimate kinase from Mycobacterium tuberculosis
Q44667602Molecular model of the neural dopamine transporter
Q33840970Molecular modeling and biochemical characterization reveal the mechanism of hepatitis B virus polymerase resistance to lamivudine (3TC) and emtricitabine (FTC).
Q33264121Molecular modeling and characterization of Vibrio cholerae transcription regulator HlyU
Q34330910Molecular modeling of drug-DNA complexes: an update
Q77121659Molecular modeling of ligand-gated ion channels
Q51007614Molecular modeling of protein-protein interaction to decipher the structural mechanism of nonhost resistance in rice.
Q34224362Molecular modeling of the membrane targeting of phospholipase C pleckstrin homology domains
Q73714910Molecular modeling of the rabbit colonic (HKalpha2a) H+, K+ ATPase
Q24644844Molecular modeling-based analysis of interactions in the RFC-dependent clamp-loading process
Q33221618Molecular models of protein kinase 6 from Plasmodium falciparum
Q41630846Molecular organization of a recombinant subviral particle from tick-borne encephalitis virus
Q34068414Molecular origins of fluorocarbon hydrophobicity
Q35014319Molecular recognition by SH2 domains
Q35014313Molecular recognition in antibody-antigen complexes
Q24324472Molecular recognition of BMP-2 and BMP receptor IA
Q34546063Molecular recognition of histone H3 by the WD40 protein WDR5.
Q34479444Molecular structure of EmbR, a response element of Ser/Thr kinase signaling in Mycobacterium tuberculosis.
Q24298361Monomeric complex of human orphan estrogen related receptor-2 with DNA: a pseudo-dimer interface mediates extended half-site recognition
Q27618675Monomeric sarcosine oxidase: structure of a covalently flavinylated amine oxidizing enzyme
Q27639948Monomeric structures of the zymogen and active catalytic domain of complement protease c1r: further insights into the c1 activation mechanism
Q27640994Moth chemosensory protein exhibits drastic conformational changes and cooperativity on ligand binding
Q28588685Mouse mast cell protease 9, a novel member of the chromosome 14 family of serine proteases that is selectively expressed in uterine mast cells
Q41112846Much more than the sum of the parts: structures of the dual SH2 domains of ZAP-70 and Syp.
Q34642787Multibody correlations in the hydrophobic solvation of glycine peptides
Q30483614Multiple functions for actin during filamentous growth of Saccharomyces cerevisiae
Q42272140Multiple hindered rotators in a gyroscope-inspired tribenzylamine hemicryptophane.
Q38361586Multisite and multivalent binding between cyanovirin-N and branched oligomannosides: calorimetric and NMR characterization
Q41834963Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1.
Q41312557Muscle proteins--their actions and interactions
Q43750426Mutagenesis and computer modelling approach to study determinants for recognition of signal peptides by the mitochondrial processing peptidase
Q31060644Mutated barley (1,3)-beta-D-glucan endohydrolases synthesize crystalline (1,3)-beta-D-glucans
Q28205734Mutation in a winged-helix DNA-binding motif causes atypical bare lymphocyte syndrome
Q50515030Mutation of Arg-54 strongly influences heme composition and rate and directionality of electron transfer in Paracoccus denitrificans cytochrome c oxidase.
Q27650096Mutation of the PDK1 PH Domain Inhibits Protein Kinase B/Akt, Leading to Small Size and Insulin Resistance
Q43033407Mutational analysis of Pyrococcus furiosus replication factor C based on the three-dimensional structure.
Q54102921Mutational analysis of active-site residues of the enterococcal D-ala-D-Ala dipeptidase VanX and comparison with Escherichia coli D-ala-D-Ala ligase and D-ala-D-Ala carboxypeptidase VanY.
Q34420970Mutational analysis of the carbohydrate binding activity of the tobacco lectin
Q41733808Mutational analysis of the major coat protein of M13 identifies residues that control protein display
Q24317292Mutations in LRP5 or FZD4 underlie the common familial exudative vitreoretinopathy locus on chromosome 11q.
Q37288233Mutations in the C-terminal fragment of DnaK affecting peptide binding
Q33575042Mutations in the DnaK chaperone affecting interaction with the DnaJ cochaperone.
Q24290985Mutations that alter the surface charge of alpha-tropomyosin are associated with dilated cardiomyopathy
Q30336343Myoglobin cavities provide interior ligand pathway.
Q27639737Myxoma virus immunomodulatory protein M156R is a structural mimic of eukaryotic translation initiation factor eIF2alpha
Q27619272N- and C-terminal residues combine in the fusion-pH influenza hemagglutinin HA(2) subunit to form an N cap that terminates the triple-stranded coiled coil
Q27745720N-terminal arm exchange is observed in the 2.15 A crystal structure of oxidized nitrite reductase from Pseudomonas aeruginosa
Q58002392NMR solution structure of Thermotoga maritima protein TM1509 reveals a Zn-metalloprotease-like tertiary structure
Q27642755NMR solution structure of the focal adhesion targeting domain of focal adhesion kinase in complex with a paxillin LD peptide: evidence for a two-site binding model
Q35130452NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region
Q27641236NMR solution structure of the non-RGD disintegrin obtustatin
Q27626381NMR structure and mutagenesis of the third Bir domain of the inhibitor of apoptosis protein XIAP
Q27734442NMR structure of inactivation gates from mammalian voltage-dependent potassium channels
Q27738191NMR structure of the 35-residue villin headpiece subdomain
Q27626634NMR structure of the N-terminal J domain of murine polyomavirus T antigens. Implications for DnaJ-like domains and for mutations of T antigens
Q33203438NMR structure of the alpha-hemoglobin stabilizing protein: insights into conformational heterogeneity and binding
Q27640762NMR structure of ubiquitin-like domain in PARKIN: gene product of familial Parkinson's disease
Q71797780NMR studies of the post-activated neocarzinostatin chromophore-DNA complex. Conformational changes induced in drug and DNA
Q27619352NSF N-terminal domain crystal structure: models of NSF function
Q42550203Nanoscale dewetting transition in protein complex folding
Q36403929Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion
Q48044883Near infrared overtone (vOH = 2 ← 0) spectroscopy of Ne-H2O clusters.
Q36748531Nebulin, a helical actin binding protein
Q37543420Negative electrostatic surface potential of protein sites specific for anionic ligands
Q34756144Neutralization of human immunodeficiency virus type 1 by sCD4-17b, a single-chain chimeric protein, based on sequential interaction of gp120 with CD4 and coreceptor
Q24800305New approaches to eliciting protective immunity through T cell repertoire manipulation: the concept of thymic vaccination
Q27749226New aspects of electron transfer revealed by the crystal structure of a truncated bovine adrenodoxin, Adx(4-108)
Q30724282New insights into intracellular lipid binding proteins: The role of buried water
Q42700491New insights into the signaling mechanism of the pH-responsive, membrane-integrated transcriptional activator CadC of Escherichia coli
Q40533143New programs for protein tertiary structure prediction
Q27620995New structural motifs on the chymotrypsin fold and their potential roles in complement factor B
Q52353173New tricks for old dogs: improving the accuracy of biomolecular force fields by pair-specific corrections to non-bonded interactions.
Q34003813Nicotinamide adenine dinucleotide metabolism as an attractive target for drug discovery
Q27640261Non-nucleoside analogue inhibitors bind to an allosteric site on HCV NS5B polymerase. Crystal structures and mechanism of inhibition
Q27729882Nonclassical binding of formylated peptide in crystal structure of the MHC class Ib molecule H2-M3
Q45022876Novel DNA bis-intercalation by MLN944, a potent clinical bisphenazine anticancer drug
Q33736676Novel Escherichia coli umuD' mutants: structure-function insights into SOS mutagenesis
Q46608644Novel HLA-A*11 allele, A*1120, identified by sequence-based typing
Q27939194Novel features of the rotary catalytic mechanism revealed in the structure of yeast F1 ATPase
Q27648921Novel hexamerization motif is discovered in a conserved cytoplasmic protein from Salmonella typhimurium
Q27639994Novel mode of ligand recognition by the Erbin PDZ domain
Q39985087Novel pathogenic mutations and skin biopsy analysis in Knobloch syndrome.
Q27632592Novel recognition mode between Vav and Grb2 SH3 domains
Q27621789Nuclear magnetic resonance solution conformation of alpha-conotoxin AuIB, an alpha(3)beta(4) subtype-selective neuronal nicotinic acetylcholine receptor antagonist
Q44389676Nuclear magnetic resonance studies on the pKa values and interaction of ionizable groups in bromelain inhibitor VI from pineapple stem
Q48046865Nuclear spin/parity dependent spectroscopy and predissociation dynamics in vOH = 2 ← 0 overtone excited Ne-H2O clusters: Theory and experiment
Q35092062Nucleocytoplasmic transport: navigating the channel
Q30431349Nucleoprotein architecture and ColE1 dimer resolution: a hypothesis
Q27617998Nucleotide binding to the G12V-mutant of Cdc42 investigated by X-ray diffraction and fluorescence spectroscopy: Two different nucleotide states in one crystal
Q44964938Nucleotide insertion opposite a cis-syn thymine dimer by a replicative DNA polymerase from bacteriophage T7.
Q46650258Nucleotide-dependent domain movement in the ATPase domain of a human type IIA DNA topoisomerase.
Q30445728Nup50/Npap60 function in nuclear protein import complex disassembly and importin recycling
Q36574089OCA-B is a functional analog of VP16 but targets a separate surface of the Oct-1 POU domain
Q42775027Oligomeric integrity--the structural key to thermal stability in bacterial alcohol dehydrogenases
Q33797989Oligomeric modeling and electrostatic analysis of the gp120 envelope glycoprotein of human immunodeficiency virus
Q40552249Oligomerization and polymerization of the filovirus matrix protein VP40.
Q36066410On defining the rules for interactions between the T cell receptor and its ligand: a critical role for a specific amino acid residue of the T cell receptor beta chain
Q41999691On the calculation of binding free energies using continuum methods: application to MHC class I protein-peptide interactions
Q42845179On the entropy of protein folding
Q73572205On the molecular interaction between lactoferrin and the dye Red HE-3b. A novel approach for docking a charged and highly flexible molecule to protein surfaces
Q44891313On the rational design of substrate mimetics: The function of docking approaches for the prediction of protease specificities
Q44021056On the role of electrostatic interactions in the design of protein-protein interfaces
Q36279656On the role of surface tension in the stabilization of globular proteins
Q27639103On the role of the conformational flexibility of the active-site lid on the allosteric kinetics of glucosamine-6-phosphate deaminase
Q30309861Open channel structure of MscL and the gating mechanism of mechanosensitive channels.
Q27643738Open-cap conformation of intramembrane protease GlpG
Q36640288Optimization of binding electrostatics: charge complementarity in the barnase-barstar protein complex.
Q35539942Order N algorithm for computation of electrostatic interactions in biomolecular systems
Q27641195Origins of peptide selectivity and phosphoinositide binding revealed by structures of disabled-1 PTB domain complexes
Q47133897Outer membrane protein folding from an energy landscape perspective
Q27642105Oxyanion hole-stabilized stereospecific isomerization in ribose-5-phosphate isomerase (Rpi)
Q27632460Oxygen access to the active site of cholesterol oxidase through a narrow channel is gated by an Arg-Glu pair
Q30482613PBEQ-Solver for online visualization of electrostatic potential of biomolecules
Q27640904PDZ tandem of human syntenin: crystal structure and functional properties
Q41395642PNA-nucleic acid complexes. Structure, stability and dynamics
Q41310110Packaging of proteases and proteoglycans in the granules of mast cells and other hematopoietic cells. A cluster of histidines on mouse mast cell protease 7 regulates its binding to heparin serglycin proteoglycans
Q34249752Packing defects as selectivity switches for drug-based protein inhibitors
Q27641956Parallel coiled-coil association of the RhoA-binding domain in Rho-kinase
Q38309315Parsing free energies of drug-DNA interactions.
Q74344372Path of an RNA ligand around the surface of the vaccinia VP39 subunit of its cognate VP39-VP55 protein heterodimer
Q27649882Pathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide-binding pocket: a multi-modal approach
Q27654645Pentameric Assembly of Potassium Channel Tetramerization Domain-Containing Protein 5
Q30652695Peptide and protein library screening defines optimal substrate motifs for AKT/PKB.
Q41605278Peptide binding by class I and class II MHC molecules
Q80141097Peptide segments in protein-protein interfaces
Q27681161Pfit Is a Structurally Novel Crohn's Disease-Associated Superantigen
Q27638712Phage P4 origin-binding domain structure reveals a mechanism for regulation of DNA-binding activity by homo- and heterodimerization of winged helix proteins
Q43410062Phase behavior of aqueous solutions containing dipolar proteins from second-order perturbation theory.
Q42118034Phenomenological partial-specific volumes for G-quadruplex DNAs
Q27765335Phosducin induces a structural change in transducin beta gamma
Q52596156Phosphatidylinositol 3-phosphate induces the membrane penetration of the FYVE domains of Vps27p and Hrs.
Q36462364Phosphatidylinositol 3-phosphate recognition and membrane docking by the FYVE domain.
Q40047105Phosphatidylinositol 3-phosphate-dependent and -independent functions of p40phox in activation of the neutrophil NADPH oxidase
Q28208070Phosphoenolpyruvate carboxylase: three-dimensional structure and molecular mechanisms
Q47819145Phospholipases A2 from Callosellasma rhodostoma venom gland cloning and sequencing of 10 of the cDNAs, three-dimensional modelling and chemical modification of the major isozyme
Q28571582Phosphorylation events associated with different states of activation of a hepatic cardiolipin/protease-activated protein kinase. Structural identity to the protein kinase N-type protein kinases
Q34261874Phosphorylation of hepatitis C virus RNA polymerases ser29 and ser42 by protein kinase C-related kinase 2 regulates viral RNA replication.
Q33911284Phosphorylation of serine 10 in histone H3 is functionally linked in vitro and in vivo to Gcn5-mediated acetylation at lysine 14.
Q28609161Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation
Q34317129Phosphorylation of the Pseudomonas aeruginosa response regulator AlgR is essential for type IV fimbria-mediated twitching motility
Q27652421Phosphorylation-dependent interaction between antigenic peptides and MHC class I: a molecular basis for the presentation of transformed self
Q27617462Photosystem I, an improved model of the stromal subunits PsaC, PsaD, and PsaE
Q41893966Physical basis of metal-binding specificity in Escherichia coli NikR
Q77530260Picture story. A powerful stroke
Q36327803Plasma membrane phosphoinositide organization by protein electrostatics
Q27655468Plasmid replication initiator RepB forms a hexamer reminiscent of ring helicases and has mobile nuclease domains
Q33345242Plasminogen alleles influence susceptibility to invasive aspergillosis
Q44776037Plasmodium falciparum purine nucleoside phosphorylase: crystal structures, immucillin inhibitors, and dual catalytic function
Q27619588Plausible phosphoenolpyruvate binding site revealed by 2.6 A structure of Mn2+-bound phosphoenolpyruvate carboxylase from Escherichia coli
Q34120310Pleckstrin homology domains and the cytoskeleton
Q56934551Poisson–Boltzmann Methods for Biomolecular Electrostatics
Q33541127Poliovirus and its cellular receptor: a molecular genetic dissection of a virus/receptor affinity interaction
Q34290782Polyamine uptake systems in Escherichia coli
Q42681932Polymorphism of two very similar MHC class Ib loci in rainbow trout (Oncorhynchus mykiss).
Q41880532Porin mutants with new channel properties
Q41785005Position-dependent interactions between cysteine residues and the helix dipole
Q41766297Post-transfer editing mechanism of a D-aminoacyl-tRNA deacylase-like domain in threonyl-tRNA synthetase from archaea
Q34029190Potassium channel structure: domain by domain
Q39475865Potent inhibitors of furin and furin-like proprotein convertases containing decarboxylated P1 arginine mimetics
Q27636180Precursor structure of cephalosporin acylase. Insights into autoproteolytic activation in a new N-terminal hydrolase family
Q35621798Predicting peptide-mediated interactions on a genome-wide scale
Q38386937Predicting protein interface residues using easily accessible on-line resources.
Q52034713Prediction of MHC class I binding peptides using profile motifs.
Q41790879Prediction of protein complexes using empirical free energy functions
Q33682938Prediction of the binding energy for small molecules, peptides and proteins
Q44673411Prediction of the binding site on E1 in the assembly of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus
Q73216554Prediction of the multimeric assembly of staphylococcal enterotoxin A with cell-surface protein receptors
Q73806954Preventing estrogen receptor action with dimer-interface peptides
Q27756637Primary and tertiary structures of the Fab fragment of a monoclonal anti-E-selectin 7A9 antibody that inhibits neutrophil attachment to endothelial cells
Q42617251Primary structure and function analysis of the Abrus precatorius agglutinin A chain by site-directed mutagenesis. Pro(199) Of amphiphilic alpha-helix H impairs protein synthesis inhibitory activity
Q33246033ProFace: a server for the analysis of the physicochemical features of protein-protein interfaces
Q42557759Probing Na(+)-induced changes in the HIV-1 TAR conformational dynamics using NMR residual dipolar couplings: new insights into the role of counterions and electrostatic interactions in adaptive recognition
Q27642640Probing Zn2+-binding effects on the zinc-ribbon domain of human general transcription factor TFIIB
Q36639386Probing protein conformation with a minimal photochemical reagent
Q34172247Probing protein-sugar interactions.
Q34836222Probing surface tension additivity on chemically heterogeneous surfaces by a molecular approach
Q46427567Probing the beta2 adrenoceptor binding site with catechol reveals differences in binding and activation by agonists and partial agonists
Q46675034Probing the determinants of substrate specificity of a feruloyl esterase, AnFaeA, from Aspergillus niger
Q34134635Probing the interface between membrane proteins and membrane lipids by X-ray crystallography
Q27766638Probing the molecular basis of allergy. three-dimensional structure of the bovine lipocalin allergen Bos d 2
Q42602636Probing the orientation of reconstituted maltoporin channels at the single-protein level
Q27641502Probing the roles of key residues in the unique regulatory NADH binding site of type II citrate synthase of Escherichia coli
Q39682437Probing the sialic acid binding site of the hemagglutinin-neuraminidase of Newcastle disease virus: identification of key amino acids involved in cell binding, catalysis, and fusion.
Q34181032Profiling charge complementarity and selectivity for binding at the protein surface
Q47721192Progress in bio-inspired sacrificial bonds in artificial polymeric materials.
Q22008749Progressive juvenile-onset punctate cataracts caused by mutation of the gammaD-crystallin gene
Q27636671Promiscuous antigen presentation by the nonclassical MHC Ib Qa-2 is enabled by a shallow, hydrophobic groove and self-stabilized peptide conformation
Q40151903Properties of spin and fluorescent labels at a receptor-ligand interface
Q47628337Properties of the protein matrix revealed by the free energy of cavity formation
Q28202800Proposed lipocalin fold for apolipoprotein M based on bioinformatics and site-directed mutagenesis
Q27658041Protein Stabilization and the Hofmeister Effect: The Role of Hydrophobic Solvation
Q27653011Protein chaperones Q8ZP25_SALTY from Salmonella typhimurium and HYAE_ECOLI from Escherichia coli exhibit thioredoxin-like structures despite lack of canonical thioredoxin active site sequence motif
Q35598491Protein electrostatics: a review of the equations and methods used to model electrostatic equations in biomolecules--applications in biotechnology
Q77729771Protein engineering the surface of enzymes
Q36111481Protein hydrogen exchange: testing current models
Q48058763Protein kinase C-epsilon is necessary for erythropoietin's up-regulation of c-myc and for factor-dependent DNA synthesis. Evidence for discrete signals for growth and differentiation
Q36216413Protein kinase Cθ C2 domain is a phosphotyrosine binding module that plays a key role in its activation
Q27619031Protein plasticity to the extreme: changing the topology of a 4-alpha-helical bundle with a single amino acid substitution
Q34563318Protein recognition by cell surface receptors: physiological receptors versus virus interactions
Q40239425Protein self-association in solution: the bovine pancreatic trypsin inhibitor decamer
Q43704478Protein tyrosine phosphatase SHP-1 specifically recognizes C-terminal residues of its substrates via helix alpha0.
Q34985071Protein-lipid interactions in the purple bacterial reaction centre
Q78488186Protein-protein and protein-DNA interactions of sigma70 region 4 involved in transcription activation by lambdacI
Q37277360Protein-protein interaction and quaternary structure
Q50093968Proteome-wide comparison between the amino acid composition of domains and linkers.
Q40242616Protocol for MM/PBSA molecular dynamics simulations of proteins
Q34203197Proton translocation by transhydrogenase
Q79313463Proton translocation by transhydrogenase
Q40159832Protonation of lysine residues inverts cation/anion selectivity in a model channel
Q34295892Pseudorevertants of a Semliki forest virus fusion-blocking mutation reveal a critical interchain interaction in the core trimer
Q77171945Purification and preliminary characterization of a serine hydrolase involved in the microbial degradation of polychlorinated biphenyls
Q57555932Purification and primary structure determination of Tf4, the first bioactive peptide isolated from the venom of the Brazilian scorpion Tityus fasciolatus
Q30982267Purification, amino-acid sequence and partial characterization of two toxins with anti-insect activity from the venom of the South American scorpion Tityus bahiensis (Buthidae).
Q46270531Purification, characterization and molecular modelling of two toxin-like proteins from the Androctonus australis Hector venom
Q47885337Purification, characterization and structural analysis of an abundant beta-1,3-glucanase from banana fruit.
Q48328357Purification, characterization, immunolocalization and structural analysis of the abundant cytoplasmic beta-amylase from Calystegia sepium (hedge bindweed) rhizomes.
Q36871814Putidaredoxin-to-cytochrome P450cam electron transfer: differences between the two reductive steps required for catalysis
Q27619164Pyruvate formate lyase is structurally homologous to type I ribonucleotide reductase
Q46793452Quantitative structure-activity relationship analysis of canonical inhibitors of serine proteases
Q24534404RNA binding in an Sm core domain: X-ray structure and functional analysis of an archaeal Sm protein complex
Q36275406RNA challenges for computational chemists
Q27626992RNA methylation under heat shock control
Q27641468RNA recognition via the SAM domain of Smaug
Q36399161RNA silencing suppressor p21 of Beet yellows virus forms an RNA binding octameric ring structure
Q27640090RNA synthesis in a cage--structural studies of reovirus polymerase lambda3
Q33292522Raf-1 kinase and exoenzyme S interact with 14-3-3zeta through a common site involving lysine 49.
Q43570152Rapeseed chloroplast thioredoxin-m. Modulation of the affinity for target proteins
Q57269729Rapid Evolution by Positive Darwinian Selection in T-Cell Antigen CD4 in Primates
Q45939376Rapid atomic density methods for molecular shape characterization.
Q24672857Rapid mapping of protein functional epitopes by combinatorial alanine scanning
Q73762639Ras-binding domains: predicting function versus folding
Q24315941Ras/Rap effector specificity determined by charge reversal
Q27860557Raster3D: photorealistic molecular graphics
Q44089221Rational cytokine design for increased lifetime and enhanced potency using pH-activated "histidine switching".
Q77634517Rational design and synthesis of phenethyl-5-bromopyridyl thiourea derivatives as potent non-nucleoside inhibitors of HIV reserve transcriptase
Q43052902Rational design of a novel calcium-binding site adjacent to the ligand-binding site on CD2 increases its CD48 affinity
Q43037048Re-evaluation of the model-free analysis of fast internal motion in proteins using NMR relaxation
Q27636047Reaction mechanism of chalcone isomerase. pH dependence, diffusion control, and product binding differences
Q30322247Receptor recognition sites of cytokines are organized as exchangeable modules. Transfer of the leukemia inhibitory factor receptor-binding site from ciliary neurotrophic factor to interleukin-6.
Q27640045Recognition of ERK MAP kinase by PEA-15 reveals a common docking site within the death domain and death effector domain
Q24292732Recognition of RNA polymerase II and transcription bubbles by XPG, CSB, and TFIIH: insights for transcription-coupled repair and Cockayne Syndrome
Q27620825Recognition of a TG mismatch: the crystal structure of very short patch repair endonuclease in complex with a DNA duplex
Q24300425Recognition of eIF4G by rotavirus NSP3 reveals a basis for mRNA circularization
Q27619753Recognition of polyadenylate RNA by the poly(A)-binding protein
Q27642741Recognition of small interfering RNA by a viral suppressor of RNA silencing
Q27643189Recognition of the mRNA AU-rich element by the zinc finger domain of TIS11d
Q27637340Recognition of the rotavirus mRNA 3' consensus by an asymmetric NSP3 homodimer
Q24792130Recognition of the spliceosomal branch site RNA helix on the basis of surface and electrostatic features
Q38315517Reconciling structure and function in HhaI DNA cytosine-C-5 methyltransferase
Q37726523Reconciling the understanding of 'hydrophobicity' with physics-based models of proteins
Q46819523Reconstitution of cyanogenesis in barley (Hordeum vulgare L.) and its implications for resistance against the barley powdery mildew fungus
Q24337238Reconstitution, activities, and structure of the eukaryotic RNA exosome
Q78429536Recovery of known T-cell epitopes by computational scanning of a viral genome
Q27642457Recurring conformation of the human immunodeficiency virus type 1 gp120 V3 loop
Q71477921Redefining the minimal antigen-binding fragment
Q41908438Reducing grid-dependence in finite-difference Poisson-Boltzmann calculations
Q30427772Refined solution structure of the anti-mammal and anti-insect LqqIII scorpion toxin: comparison with other scorpion toxins
Q27733996Refined solution structure of type III antifreeze protein: hydrophobic groups may be involved in the energetics of the protein-ice interaction
Q36280403Refined structure of villin 14T and a detailed comparison with other actin-severing domains
Q33689010Regulation of DNA-dependent activities by the functional motifs of the high-mobility-group chromosomal proteins
Q35063194Regulation of cardiac myocyte cell death
Q33339698Relation between the convergence temperatures Th* and Ts* in protein unfolding
Q29048141Remarkably similar antigen receptors among a subset of patients with chronic lymphocytic leukemia
Q42847632Removal of the N-terminal hexapeptide from human beta2-microglobulin facilitates protein aggregation and fibril formation
Q30329984Rescuing the function of mutant p53.
Q37595635Resolution of the novel immune-type receptor gene cluster in zebrafish
Q42804986Resolving fast and slow motions in the internal loop containing stem-loop 1 of HIV-1 that are modulated by Mg2+ binding: role in the kissing-duplex structural transition
Q27630643Restriction enzyme BsoBI-DNA complex: a tunnel for recognition of degenerate DNA sequences and potential histidine catalysis
Q41244531Retroviral capsid assembly: a role for the CA dimer in initiation
Q43030413Reversal of halophilicity in a protein-DNA interaction by limited mutation strategy
Q27701624Reversibility and two state behaviour in the thermal unfolding of oligomeric TIM barrel proteins
Q44889831Rhamnogalacturonan lyase reveals a unique three-domain modular structure for polysaccharide lyase family 4.
Q27631719Ribosomal protein L5 has a highly twisted concave surface and flexible arms responsible for rRNA binding
Q27745831Ribosomal protein S7: a new RNA-binding motif with structural similarities to a DNA architectural factor
Q47923424Ribosomal proteins S5 and L6: high-resolution crystal structures and roles in protein synthesis and antibiotic resistance
Q27639870Ribosome-associated factor Y adopts a fold resembling a double-stranded RNA binding domain scaffold
Q47858571Ribozyme catalysis from the major groove of group II intron domain 5.
Q38350098Ricin A-chain structural determinant for binding substrate analogues: a molecular dynamics simulation analysis
Q34651364Rigidity and flexibility of dipeptidyl peptidase IV: crystal structures of and docking experiments with DPIV.
Q47071807Role of Drosophila gene dunc-115 in nervous system
Q27631672Role of a cluster of hydrophobic residues near the FAD cofactor in Anabaena PCC 7119 ferredoxin-NADP+ reductase for optimal complex formation and electron transfer to ferredoxin
Q30998001Role of cysteine residues in structural stability and function of a transmembrane helix bundle.
Q47954659Role of electrostatic interactions on the affinity of thioredoxin for target proteins. Recognition of chloroplast fructose-1, 6-bisphosphatase by mutant Escherichia coli thioredoxins
Q78553241Role of electrostatics in the interaction between plastocyanin and photosystem I of the cyanobacterium Phormidium laminosum
Q44179253Role of hydration in the binding of lac repressor to DNA.
Q38341659Role of sialyloligosaccharide binding in Theiler's virus persistence.
Q21092775Role of the AP2 beta-appendage hub in recruiting partners for clathrin-coated vesicle assembly
Q37143313Role of the extracellular loops of G protein-coupled receptors in ligand recognition: a molecular modeling study of the human P2Y1 receptor.
Q40638638Role of the gp120 inner domain beta-sandwich in the interaction between the human immunodeficiency virus envelope glycoprotein subunits
Q40737828Roles of catalytic domain residues in interfacial binding and activation of group IV cytosolic phospholipase A2.
Q52038687Roles of hydration water molecules in molecular packing of the killer toxin from Pichia farinosa in its crystalline state investigated by cryogenic X-ray crystallography.
Q44353901Roles of individual domains and conserved motifs of the AAA+ chaperone ClpB in oligomerization, ATP hydrolysis, and chaperone activity
Q27639008Rotavirus protein involved in genome replication and packaging exhibits a HIT-like fold
Q24600321Rules for nuclear localization sequence recognition by karyopherin beta 2
Q24678799SH3 domain recognition of a proline-independent tyrosine-based RKxxYxxY motif in immune cell adaptor SKAP55
Q24672033STING Millennium: A web-based suite of programs for comprehensive and simultaneous analysis of protein structure and sequence
Q24558575STING Report: convenient web-based application for graphic and tabular presentations of protein sequence, structure and function descriptors from the STING database
Q74072084SUMO wrestling with specificity
Q33638750Saccharide-RNA recognition
Q27619183Saccharide-RNA recognition in a complex formed between neomycin B and an RNA aptamer
Q27735003Saccharide-RNA recognition in an aminoglycoside antibiotic-RNA aptamer complex
Q44470154Salt modulates the stability and lipid binding affinity of the adipocyte lipid-binding proteins
Q34172050Sampling field heterogeneity at the heme of c-type cytochromes by spectral hole burning spectroscopy and electrostatic calculations
Q30830076Savignygrin, a platelet aggregation inhibitor from the soft tick Ornithodoros savignyi, presents the RGD integrin recognition motif on the Kunitz-BPTI fold.
Q52077262Scoring docked conformations generated by rigid-body protein-protein docking.
Q24600140Second sialic acid binding site in Newcastle disease virus hemagglutinin-neuraminidase: implications for fusion
Q27649386Segrosome structure revealed by a complex of ParR with centromere DNA
Q30321823Selecting near-native conformations in homology modeling: the role of molecular mechanics and solvation terms
Q33797964Selective interactions of polyanions with basic surfaces on human immunodeficiency virus type 1 gp120
Q38880491Self-aligning amelogenin nanoribbons in oil-water system
Q34479797Self-fulfilling cavitands: packing alkyl chains into small spaces
Q43678259Sequence analyses and comparative modeling of fly and worm fibroblast growth factor receptors indicate that the determinants for FGF and heparin binding are retained in evolution
Q37268036Sequence specific and high affinity recognition of 5'-ACGCGT-3' by rationally designed pyrrole-imidazole H-pin polyamides: thermodynamic and structural studies
Q73755061Sequence variability analysis of human class I and class II MHC molecules: functional and structural correlates of amino acid polymorphisms
Q30341688Sequence-specific DNA binding determined by contacts outside the helix-turn-helix motif of the ParB homolog KorB.
Q24536014Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain
Q27648683Sequential Aldol Condensation Catalyzed by Hyperthermophilic 2-Deoxy-D-Ribose-5-Phosphate Aldolase
Q24532839Several cooperating binding sites mediate the interaction of a lysosomal enzyme with phosphotransferase
Q48072975Sexual and apomictic seed formation in Hieracium requires the plant polycomb-group gene FERTILIZATION INDEPENDENT ENDOSPERM.
Q27621246Sexual attraction in the silkworm moth: structure of the pheromone-binding-protein-bombykol complex
Q74451838Shapes of MHC restriction
Q27766377Sheep liver cytosolic aldehyde dehydrogenase: the structure reveals the basis for the retinal specificity of class 1 aldehyde dehydrogenases
Q27639916Short constrained peptides that inhibit HIV-1 entry
Q36450439Side chain and backbone contributions of Phe508 to CFTR folding
Q34732367Side-chain conformational entropy in protein folding
Q24532099Signal-dependent membrane targeting by pleckstrin homology (PH) domains
Q35808801Signatures of hydrophobic collapse in extended proteins captured with force spectroscopy
Q27655733Silicon analogues of the RXR-selective retinoid agonist SR11237 (BMS649): chemistry and biology
Q52076316Simulation of electrostatic effects in Fab-antigen complex formation.
Q35234470Single-molecule transition-state analysis of RNA folding
Q28487166Siroheme- and [Fe4-S4]-dependent NirA from Mycobacterium tuberculosis is a sulfite reductase with a covalent Cys-Tyr bond in the active site
Q30307668Site-directed spin-labeling analysis of reconstituted Mscl in the closed state.
Q36173765Site-specific hydration dynamics of globular proteins and the role of constrained water in solvent exchange with amphiphilic cosolvents.
Q27642862Size selective recognition of siRNA by an RNA silencing suppressor
Q47946960Snapshots of replication through an abasic lesion; structural basis for base substitutions and frameshifts
Q27649838Solution NMR Structures of Productive and Non-productive Complexes between the A and B Domains of the Cytoplasmic Subunit of the Mannose Transporter of the Escherichia coli Phosphotransferase System
Q27640686Solution NMR structure of ribosome-binding factor A (RbfA), a cold-shock adaptation protein from Escherichia coli
Q27642596Solution NMR structure of the 30S ribosomal protein S28E fromPyrococcus horikoshii
Q34327302Solution NMR structure of the 48-kDa IIAMannose-HPr complex of the Escherichia coli mannose phosphotransferase system
Q36519194Solution NMR structure of the C-terminal domain of the human protein DEK.
Q27649727Solution NMR structure of the N-terminal domain of the human DEK protein
Q27683102Solution Structure and DNA-binding Properties of the Winged Helix Domain of the Meiotic Recombination HOP2 Protein
Q27655389Solution Structure of Factor I-like Modules from Complement C7 Reveals a Pair of Follistatin Domains in Compact Pseudosymmetric Arrangement
Q27679135Solution Structure of the IIAChitobiose-HPr Complex of the N,N'-Diacetylchitobiose Branch of the Escherichia coli Phosphotransferase System
Q27658430Solution Structure of the IIAChitobiose-IIBChitobiose Complex of the N,N'-Diacetylchitobiose Branch of the Escherichia coli Phosphotransferase System
Q27748755Solution Structure of the KIX Domain of CBP Bound to the Transactivation Domain of CREB: A Model for Activator:Coactivator Interactions
Q27642513Solution Structure of the Third TB Domain from LTBP1 Provides Insight into Assembly of the Large Latent Complex that Sequesters Latent TGF-β
Q27667329Solution Structure of the mSin3A PAH2–Pf1 SID1 Complex: A Mad1/Mxd1-Like Interaction Disrupted by MRG15 in the Rpd3S/Sin3S Complex
Q27638952Solution structure and backbone dynamics of an antigen-free heavy chain variable domain (VHH) from Llama
Q24534139Solution structure and backbone dynamics of human epidermal-type fatty acid-binding protein (E-FABP)
Q34447967Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1.
Q27648906Solution structure and calcium-binding properties of EF-hands 3 and 4 of calsenilin
Q27671565Solution structure and dynamics of ADF from Toxoplasma gondii
Q27633250Solution structure and dynamics of ribonuclease Sa
Q24292283Solution structure and dynamics of the lipoic acid-bearing domain of human mitochondrial branched-chain alpha-keto acid dehydrogenase complex
Q36518062Solution structure of APETx2, a specific peptide inhibitor of ASIC3 proton-gated channels
Q36476571Solution structure of Archaeglobus fulgidis peptidyl-tRNA hydrolase (Pth2) provides evidence for an extensive conserved family of Pth2 enzymes in archea, bacteria, and eukaryotes
Q27617719Solution structure of BID, an intracellular amplifier of apoptotic signaling
Q27748760Solution structure of Der f 2, the major mite allergen for atopic diseases
Q24672462Solution structure of DinI provides insight into its mode of RecA inactivation
Q27625497Solution structure of N-TRADD and characterization of the interaction of N-TRADD and C-TRAF2, a key step in the TNFR1 signaling pathway
Q27638266Solution structure of N-terminal SH3 domain of Vav and the recognition site for Grb2 C-terminal SH3 domain
Q27748927Solution structure of P22 transcriptional antitermination N peptide-boxB RNA complex
Q27622440Solution structure of PCP, a prototype for the peptidyl carrier domains of modular peptide synthetases
Q36474020Solution structure of PcFK1, a spider peptide active against Plasmodium falciparum.
Q24645107Solution structure of Phrixotoxin 1, a specific peptide inhibitor of Kv4 potassium channels from the venom of the theraphosid spider Phrixotrichus auratus
Q27642010Solution structure of Vps27 UIM-ubiquitin complex important for endosomal sorting and receptor downregulation
Q27642929Solution structure of a BolA-like protein from Mus musculus
Q27641386Solution structure of a CUE-ubiquitin complex reveals a conserved mode of ubiquitin binding
Q27637321Solution structure of a K+-channel blocker from the scorpion Tityus cambridgei
Q27634867Solution structure of a Kunitz-type chymotrypsin inhibitor isolated from the elapid snake Bungarus fasciatus
Q27640135Solution structure of a circular-permuted variant of the potent HIV-inactivating protein cyanovirin-N: structural basis for protein stability and oligosaccharide interaction
Q27635270Solution structure of a cyanovirin-N:Man alpha 1-2Man alpha complex: structural basis for high-affinity carbohydrate-mediated binding to gp120
Q41891400Solution structure of a mini IGF-1
Q27732655Solution structure of a peptide nucleic acid-DNA duplex
Q46917261Solution structure of a post-transition state analog of the phosphotransfer reaction between the A and B cytoplasmic domains of the mannitol transporter IIMannitol of the Escherichia coli phosphotransferase system
Q27730895Solution structure of a pyrimidine.purine.pyrimidine DNA triplex containing T.AT, C+.GC and G.TA triples
Q27620561Solution structure of a recombinant mouse major urinary protein
Q27636679Solution structure of a telomeric DNA complex of human TRF1
Q36811352Solution structure of an antiparallel purine motif triplex containing a T.CG pyrimidine base triple
Q27739188Solution structure of an rRNA methyltransferase (ErmAM) that confers macrolide-lincosamide-streptogramin antibiotic resistance
Q44895863Solution structure of atypical protein kinase C PB1 domain and its mode of interaction with ZIP/p62 and MEK5.
Q33739670Solution structure of choline binding protein A, the major adhesin of Streptococcus pneumoniae
Q27764577Solution structure of cyanovirin-N, a potent HIV-inactivating protein
Q37073358Solution structure of dengue virus capsid protein reveals another fold
Q27643034Solution structure of domain 5 of a group II intron ribozyme reveals a new RNA motif
Q34439534Solution structure of drosomycin, the first inducible antifungal protein from insects
Q24318763Solution structure of histone chaperone ANP32B: interaction with core histones H3-H4 through its acidic concave domain
Q27640755Solution structure of human BCL-w: modulation of ligand binding by the C-terminal helix
Q27622508Solution structure of ileal lipid binding protein in complex with glycocholate
Q27765088Solution structure of the DNA- and RPA-binding domain of the human repair factor XPA
Q27746093Solution structure of the DNA-binding domain and model for the complex of multifunctional hexameric arginine repressor with DNA
Q27626645Solution structure of the E200K variant of human prion protein. Implications for the mechanism of pathogenesis in familial prion diseases
Q27618091Solution structure of the HMG protein NHP6A and its interaction with DNA reveals the structural determinants for non-sequence-specific binding
Q51391237Solution structure of the HMG-box domain in the SSRP1 subunit of FACT.
Q27749659Solution structure of the IRF-2 DNA-binding domain: a novel subgroup of the winged helix-turn-helix family
Q27638848Solution structure of the LicT-RNA antitermination complex: CAT clamping RAT.
Q22254245Solution structure of the MEF2A-DNA complex: structural basis for the modulation of DNA bending and specificity by MADS-box transcription factors
Q33887936Solution structure of the Mu end DNA-binding ibeta subdomain of phage Mu transposase: modular DNA recognition by two tethered domains.
Q27740763Solution structure of the N-terminal zinc binding domain of HIV-1 integrase
Q24290873Solution structure of the PHD domain from the KAP-1 corepressor: structural determinants for PHD, RING and LIM zinc-binding domains
Q28506043Solution structure of the PWWP domain of the hepatoma-derived growth factor family
Q27651937Solution structure of the Pseudomonas putida protein PpPutA45 and its DNA complex
Q27764927Solution structure of the RAIDD CARD and model for CARD/CARD interaction in caspase-2 and caspase-9 recruitment
Q27622724Solution structure of the RNA polymerase subunit RPB5 from Methanobacterium thermoautotrophicum
Q27630598Solution structure of the antiapoptotic protein bcl-2
Q27618997Solution structure of the catalytic domain of GCN5 histone acetyltransferase bound to coenzyme A
Q27765728Solution structure of the cellular factor BAF responsible for protecting retroviral DNA from autointegration
Q27622344Solution structure of the chitin-binding domain of Bacillus circulans WL-12 chitinase A1
Q27634037Solution structure of the constant region of nuclear envelope protein LAP2 reveals two LEM-domain structures: one binds BAF and the other binds DNA
Q27640505Solution structure of the cytotoxic RNase 4 from oocytes of bullfrog Rana catesbeiana
Q27733381Solution structure of the donor site of a trans-splicing RNA
Q27635366Solution structure of the fibronectin type III domain from Bacillus circulans WL-12 chitinase A1
Q27628157Solution structure of the focal adhesion adaptor PINCH LIM1 domain and characterization of its interaction with the integrin-linked kinase ankyrin repeat domain
Q47301247Solution structure of the hypothetical protein SAV1595 from Staphylococcus aureus, a putative RNA binding protein
Q27628842Solution structure of the interacting domains of the Mad-Sin3 complex: implications for recruitment of a chromatin-modifying complex
Q27641889Solution structure of the mature HIV-1 protease monomer: insight into the tertiary fold and stability of a precursor
Q24291251Solution structure of the methyl-CpG binding domain of human MBD1 in complex with methylated DNA
Q53654567Solution structure of the mouse enhancer of rudimentary protein reveals a novel fold.
Q27648971Solution structure of the novel dispersin protein of enteroaggregative Escherichia coli
Q27734074Solution structure of the origin DNA-binding domain of SV40 T-antigen
Q27639553Solution structure of the phosphoryl transfer complex between the cytoplasmic A domain of the mannitol transporter IIMannitol and HPr of the Escherichia coli phosphotransferase system
Q27627801Solution structure of the phosphoryl transfer complex between the signal transducing proteins HPr and IIAGlucose of the Escherichia coli phosphoenolpyruvate:sugar phosphotransferase system
Q27641064Solution structure of the phosphoryl transfer complex between the signal-transducing protein IIAGlucose and the cytoplasmic domain of the glucose transporter IICBGlucose of the Escherichia coli glucose phosphotransferase system
Q27617723Solution structure of the proapoptotic molecule BID: a structural basis for apoptotic agonists and antagonists
Q27734306Solution structure of the ribosomal RNA binding protein S15 from Thermus thermophilus
Q27639234Solution structure of the single-domain prolyl cis/trans isomerase PIN1At from Arabidopsis thaliana
Q27736524Solution structure of the sodium channel antagonist conotoxin GS: a new molecular caliper for probing sodium channel geometry
Q27643641Solution structure of the twelfth cysteine-rich ligand-binding repeat in rat megalin
Q27641508Solution structure ofVibrio choleraeprotein VC0424: A variation of the ferredoxin-like fold
Q27636024Solution structure, hydrodynamics and thermodynamics of the UvrB C-terminal domain
Q35077481Solution structures and dynamics of ADF/cofilins UNC-60A and UNC-60B from Caenorhabditis elegans
Q54104321Solvent-exposed residues in the Tet repressor (TetR) four-helix bundle contribute to subunit recognition and dimer stability.
Q28508563Sonic hedgehog protein signals not as a hydrolytic enzyme but as an apparent ligand for patched
Q28212964Spatial clustering of isozyme-specific residues reveals unlikely determinants of isozyme specificity in fructose-1,6-bisphosphate aldolase
Q24314461Spatial constraints on the recognition of phosphoproteins by the tandem SH2 domains of the phosphatase SH-PTP2
Q52546897Spatial localization of the K+ channel selectivity filter by mutant cycle-based structure analysis.
Q27732680Specific interactions outside the proline-rich core of two classes of Src homology 3 ligands
Q27737133Specific protein recognition of an mRNA cap through its alkylated base
Q24645321Specific recognition of RNA/DNA hybrid and enhancement of human RNase H1 activity by HBD
Q39755114Specific residues in the connector loop of the human cytomegalovirus DNA polymerase accessory protein UL44 are crucial for interaction with the UL54 catalytic subunit.
Q27646401Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase
Q33854043Specificity of cell-cell adhesion by classical cadherins: Critical role for low-affinity dimerization through beta-strand swapping
Q44741670Specificity of protein-DNA recognition revealed by structure-based potentials: symmetric/asymmetric and cognate/non-cognate binding
Q27638765Sperm coating mechanism from the 1.8 A crystal structure of PDC-109-phosphorylcholine complex
Q27629437Spin-system heterogeneities indicate a selected-fit mechanism in fatty acid binding to heart-type fatty acid-binding protein (H-FABP)
Q34473484Ssk1p response regulator binding surface on histidine-containing phosphotransfer protein Ypd1p
Q73403638Stability analysis for the cavity-filling mutations of the Myb DNA-binding domain utilizing free-energy calculations
Q34361680Stabilization of the soluble, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1.
Q27644368Stacking Effects on Local Structure in RNA:  Changes in the Structure of Tandem GA Pairs when Flanking GC Pairs Are Replaced by isoG−isoC Pairs †
Q27649310Staphylococcus aureus DsbA does not have a destabilizing disulfide. A new paradigm for bacterial oxidative folding
Q34040064Stark effect experiments in cytochrome c-type proteins: structural hierarchies
Q27651396Statistical Coupling Analysis of Aspartic Proteinases Based on Crystal Structures of the Trichoderma reesei Enzyme and Its Complex with Pepstatin A
Q27640129Stepwise adaptations of citrate synthase to survival at life's extremes. From psychrophile to hyperthermophile
Q44543301Stereospecific interactions of proline residues in protein structures and complexes
Q33285969Strategies for developing protein tyrosine phosphatase inhibitors
Q27641229Structural Basis for Antibody Catalysis of a Cationic Cyclization Reaction
Q27654559Structural Basis for Antibody Discrimination between Two Hormones That Recognize the Parathyroid Hormone Receptor
Q27644454Structural Basis for Bile Salt Inhibition of Pancreatic Phospholipase A2
Q27639050Structural Basis for Broad Substrate Specificity in Higher Plant beta-D-Glucan Glucohydrolases
Q27659192Structural Basis for Lipid-Antigen Recognition in Avian Immunity
Q27639258Structural Basis for the Modulation of Lignin Monomer Methylation by Caffeic Acid/5-Hydroxyferulic Acid 3/5-O-Methyltransferase
Q29011600Structural Basis of Caspase Inhibition by XIAP
Q27678109Structural Basis of Ets1 Cooperative Binding to Widely Separated Sites on Promoter DNA
Q27643949Structural Basis of the Catalytic Mechanism Operating in Open-Closed Conformers of Lipocalin Type Prostaglandin D Synthase
Q27642427Structural Characterization of EMS16, an Antagonist of Collagen Receptor (GPIa/IIa) from the Venom of Echis multisquamatus,
Q27675877Structural Characterization of a Mouse Ortholog of Human NEIL3 with a Marked Preference for Single-Stranded DNA
Q27638941Structural Comparison of Allogeneic and Syngeneic T Cell Receptor–Peptide-Major Histocompatibility Complex Complexes
Q27681012Structural Insights into Assembly and Regulation of the Plasma Membrane Phosphatidylinositol 4-Kinase Complex
Q27653879Structural Insights into the Extracytoplasmic Thiamine-Binding Lipoprotein p37 of Mycoplasma hyorhinis
Q58402585Structural Investigation ofBorrelia burgdorferiOspB, a BactericidalFab Target
Q74403360Structural Modelling of the Sm-like Protein Hfq from Escherichia coli
Q27741079Structural adaptations in the specialized bacteriophage T4 co-chaperonin Gp31 expand the size of the Anfinsen cage
Q27749365Structural adaptations of the cold-active citrate synthase from an Antarctic bacterium
Q27619633Structural analysis of 14-3-3 phosphopeptide complexes identifies a dual role for the nuclear export signal of 14-3-3 in ligand binding
Q27640497Structural analysis of Bacillus subtilis SPP1 phage helicase loader protein G39P
Q27641579Structural analysis of Saccharomyces cerevisiae myo-inositol phosphate synthase
Q34581109Structural analysis of a rhomboid family intramembrane protease reveals a gating mechanism for substrate entry
Q27645684Structural analysis of conserved oligomeric Golgi complex subunit 2
Q28610913Structural analysis of engineered Bb fragment of complement factor B: insights into the activation mechanism of the alternative pathway C3-convertase
Q43798675Structural analysis of free and enzyme-bound amaranth alpha-amylase inhibitor: classification within the knottin fold superfamily and analysis of its functional flexibility
Q27641275Structural analysis of mycobacterial and murine hsp60 epitopes in complex with the class I MHC molecule H-2Db
Q37511109Structural analysis of p185c-neu and epidermal growth factor receptor tyrosine kinases: oligomerization of kinase domains
Q28198048Structural analysis of receptor tyrosine kinases
Q27732810Structural analysis of substrate binding by the molecular chaperone DnaK
Q34390330Structural analysis of the Laetiporus sulphureus hemolytic pore-forming lectin in complex with sugars
Q28909851Structural analysis of the complement control protein (CCP) modules of GABA(B) receptor 1a: only one of the two CCP modules is compactly folded
Q24338556Structural analysis of the human Golgi-associated plant pathogenesis related protein GAPR-1 implicates dimerization as a regulatory mechanism
Q46594070Structural analysis of the jacalin-related lectin MornigaM from the black mulberry (Morus nigra) in complex with mannose.
Q27619043Structural analysis of the lymphocyte-specific kinase Lck in complex with non-selective and Src family selective kinase inhibitors
Q27642976Structural analysis of the sialyltransferase CstII from Campylobacter jejuni in complex with a substrate analog
Q44889377Structural analysis of the voltage-dependent calcium channel beta subunit functional core and its complex with the alpha 1 interaction domain
Q27653616Structural analysis reveals DNA binding properties of Rv2827c, a hypothetical protein from Mycobacterium tuberculosis
Q24814019Structural and DNA-binding studies on the bovine antimicrobial peptide, indolicidin: evidence for multiple conformations involved in binding to membranes and DNA
Q27655362Structural and Functional Analysis of the Globular Head Domain of p115 Provides Insight into Membrane Tethering
Q77889147Structural and biochemical analysis of Ras-effector signaling via RalGDS
Q27639957Structural and biochemical analysis of the Obg GTP binding protein
Q24305176Structural and biochemical analysis reveal pirins to possess quercetinase activity
Q27626899Structural and biochemical basis of apoptotic activation by Smac/DIABLO
Q36393196Structural and biochemical characterization of a novel Mn2+-dependent phosphodiesterase encoded by the yfcE gene.
Q22010069Structural and biochemical evaluation of the interaction of the phosphatidylinositol 3-kinase p85alpha Src homology 2 domains with phosphoinositides and inositol polyphosphates
Q45197483Structural and biochemical evidence for an enzymatic quinone redox cycle in Escherichia coli: identification of a novel quinol monooxygenase
Q27666866Structural and biochemical studies of the 5′→3′ exoribonuclease Xrn1
Q34322152Structural and biochemical studies of the substrate selectivity of carnitine acetyltransferase
Q28649577Structural and catalytic effects of proline substitution and surface loop deletion in the extended active site of human carbonic anhydrase II
Q27630537Structural and energetic analysis of RNA recognition by a universally conserved protein from the signal recognition particle
Q27635422Structural and functional analysis of interhelical interactions in the human immunodeficiency virus type 1 gp41 envelope glycoprotein by alanine-scanning mutagenesis
Q47926421Structural and functional analysis of the costimulatory receptor programmed death-1.
Q27639783Structural and functional analysis of the kid toxin protein from E. coli plasmid R1
Q27739821Structural and functional analysis of the mitotic rotamase Pin1 suggests substrate recognition is phosphorylation dependent
Q27636951Structural and functional characterization of a monoclonal antibody specific for the preS1 region of hepatitis B virus
Q44885015Structural and functional characterization of a novel phosphodiesterase from Methanococcus jannaschii
Q27640170Structural and functional characterization of the Pseudomonas hydroperoxide resistance protein Ohr.
Q24810234Structural and functional characterizations reveal the importance of a zinc binding domain in Bloom's syndrome helicase
Q28488939Structural and functional evidence for Bacillus subtilis PaiA as a novel N1-spermidine/spermine acetyltransferase
Q27642598Structural and functional features of theEscherichia colihydroperoxide resistance protein OsmC
Q27641410Structural and functional insights into PINCH LIM4 domain-mediated integrin signaling
Q41614563Structural and functional properties of low molecular weight endo-1,4-beta-xylanases
Q33821613Structural and functional similarities between the capsid proteins of bacteriophages T4 and HK97 point to a common ancestry
Q54453528Structural and functional studies of RegB, a new member of a family of sequence-specific ribonucleases involved in mRNA inactivation on the ribosome.
Q27647301Structural and functional studies of the abundant tegument protein ORF52 from murine gammaherpesvirus 68
Q36174115Structural and functional studies on the tetraheme cytochrome subunit and its electron donor proteins: the possible docking mechanisms during the electron transfer reaction
Q27643935Structural and mechanistic analyses of endo-glycoceramidase II, a membrane-associated family 5 glycosidase in the Apo and GM3 ganglioside-bound forms
Q27654558Structural and mechanistic insights into the association of PKC -C2 domain to PtdIns(4,5)P2
Q27646147Structural and membrane binding analysis of the Phox homology domain of Bem1p: basis of phosphatidylinositol 4-phosphate specificity
Q34168816Structural and morphological characterization of ultralente insulin crystals by atomic force microscopy: evidence of hydrophobically driven assembly
Q27618131Structural and mutagenesis studies of leishmania triosephosphate isomerase: a point mutation can convert a mesophilic enzyme into a superstable enzyme without losing catalytic power
Q46449916Structural and mutational analysis of Trypanosoma brucei prostaglandin H2 reductase provides insight into the catalytic mechanism of aldo-ketoreductases
Q34392501Structural and mutational analysis of the SBDS protein family. Insight into the leukemia-associated Shwachman-Diamond Syndrome
Q37583444Structural and thermodynamic basis for the binding of TMC114, a next-generation human immunodeficiency virus type 1 protease inhibitor
Q27642826Structural bases for CRMP function in plexin-dependent semaphorin3A signaling
Q34466516Structural basis and prediction of substrate specificity in protein serine/threonine kinases
Q24294933Structural basis by which alternative splicing confers specificity in fibroblast growth factor receptors
Q36404007Structural basis for CD1d presentation of a sulfatide derived from myelin and its implications for autoimmunity
Q28271512Structural basis for Ca(2+)-induced activation of human PAD4
Q48021409Structural basis for Duffy recognition by the malaria parasite Duffy-binding-like domain.
Q27637899Structural basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin-conjugating enzyme Ubc9 and RanGAP1
Q22010544Structural basis for FGF receptor dimerization and activation
Q24633885Structural basis for HLA-DQ2-mediated presentation of gluten epitopes in celiac disease
Q33888460Structural basis for MutH activation in E.coli mismatch repair and relationship of MutH to restriction endonucleases
Q27642310Structural basis for Nup2p function in cargo release and karyopherin recycling in nuclear import
Q34581115Structural basis for SENP2 protease interactions with SUMO precursors and conjugated substrates
Q27641338Structural basis for SH3 domain-mediated high-affinity binding between Mona/Gads and SLP-76
Q28247758Structural basis for acceptor substrate recognition of a human glucuronyltransferase, GlcAT-P, an enzyme critical in the biosynthesis of the carbohydrate epitope HNK-1
Q34442255Structural basis for activation of fibroblast growth factor signaling by sucrose octasulfate
Q27734052Structural basis for activation of human lymphocyte kinase Lck upon tyrosine phosphorylation
Q22004264Structural basis for activation of the titin kinase domain during myofibrillogenesis
Q24336004Structural basis for amplifying vinculin activation by talin
Q46639843Structural basis for antagonism by suramin of heparin binding to vaccinia complement protein
Q27635000Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region
Q24338462Structural basis for budding by the ESCRT-III factor CHMP3
Q27627138Structural basis for catalysis and inhibition of N-glycan processing class I alpha 1,2-mannosidases
Q39959566Structural basis for channelling mechanism of a fatty acid beta-oxidation multienzyme complex
Q27617952Structural basis for cold adaptation. Sequence, biochemical properties, and crystal structure of malate dehydrogenase from a psychrophile Aquaspirillium arcticum
Q27638092Structural basis for cooperative DNA binding by two dimers of the multidrug-binding protein QacR
Q45643870Structural basis for coronavirus-mediated membrane fusion. Crystal structure of mouse hepatitis virus spike protein fusion core
Q37544348Structural basis for differential recognition of tyrosine-phosphorylated sites in the linker for activation of T cells (LAT) by the adaptor Gads
Q27626998Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains
Q27736639Structural basis for dual excitation and photoisomerization of the Aequorea victoria green fluorescent protein
Q37270556Structural basis for host recognition by the Haemophilus influenzae Hia autotransporter
Q44020898Structural basis for inhibition of cyclin-dependent kinase 9 by flavopiridol
Q27642009Structural basis for modulation and agonist specificity of HCN pacemaker channels
Q27637088Structural basis for neurofibromatosis type 2. Crystal structure of the merlin FERM domain
Q24530087Structural basis for ordered substrate binding and cooperativity in aspartate transcarbamoylase
Q28262499Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain
Q27617867Structural basis for paramyxovirus-mediated membrane fusion
Q27640370Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase
Q27638768Structural basis for proofreading during replication of the Escherichia coli chromosome
Q27621681Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA
Q27638018Structural basis for recognition of acidic-cluster dileucine sequence by GGA1
Q27646866Structural basis for recognition of high mannose type glycoproteins by mammalian transport lectin VIP36
Q27619940Structural basis for recognition of phosphorylated high mannose oligosaccharides by the cation-dependent mannose 6-phosphate receptor
Q30160164Structural basis for recognition of the T cell adaptor protein SLP-76 by the SH3 domain of phospholipase Cgamma1
Q35133849Structural basis for recognition of the nonclassical MHC molecule HLA-G by the leukocyte Ig-like receptor B2 (LILRB2/LIR2/ILT4/CD85d)
Q24534120Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha
Q41106952Structural basis for recruitment of human flap endonuclease 1 to PCNA
Q27646775Structural basis for regulation of protein phosphatase 1 by inhibitor-2
Q27627224Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation
Q27643123Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase
Q27733158Structural basis for selectivity of the isoquinoline sulfonamide family of protein kinase inhibitors
Q27617947Structural basis for self-association and receptor recognition of human TRAF2
Q27760566Structural basis for sequence-nonspecific recognition of 5'-capped mRNA by a cap-modifying enzyme
Q24290524Structural basis for signal transduction by the Toll/interleukin-1 receptor domains
Q27640932Structural basis for simultaneous binding of two carboxy-terminal peptides of plant glutamate decarboxylase to calmodulin
Q24672052Structural basis for specific binding of Polycomb chromodomain to histone H3 methylated at Lys 27
Q27643661Structural basis for stem cell factor–KIT signaling and activation of class III receptor tyrosine kinases
Q27642020Structural basis for tetrodotoxin-resistant sodium channel binding by mu-conotoxin SmIIIA
Q48013061Structural basis for the EBA-175 erythrocyte invasion pathway of the malaria parasite Plasmodium falciparum
Q27639933Structural basis for the Golgi membrane recruitment of Sly1p by Sed5p
Q24292214Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin
Q27732611Structural basis for the autoinhibition of calcium/calmodulin-dependent protein kinase I
Q24300838Structural basis for the coordinated regulation of transglutaminase 3 by guanine nucleotides and calcium/magnesium
Q27733235Structural basis for the excision repair of alkylation-damaged DNA
Q36403197Structural basis for the function and regulation of the receptor protein tyrosine phosphatase CD45
Q41459282Structural basis for the function of stringent starvation protein a as a transcription factor.
Q22254263Structural basis for the heterodimeric interaction between the acute leukaemia-associated transcription factors AML1 and CBFbeta
Q27630171Structural basis for the inactivation of retinoblastoma tumor suppressor by SV40 large T antigen
Q24316078Structural basis for the inhibition mechanism of human cystathionine gamma-lyase, an enzyme responsible for the production of H(2)S
Q27758740Structural basis for the interaction of Ras with RalGDS
Q27641082Structural basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP
Q24646957Structural basis for the product specificity of histone lysine methyltransferases
Q24291748Structural basis for the recognition of a nucleoporin FG repeat by the NTF2-like domain of the TAP/p15 mRNA nuclear export factor
Q36399657Structural basis for the restoration of TCR recognition of an MHC allelic variant by peptide secondary anchor substitution
Q24300730Structural basis for the reversible activation of a Rho protein by the bacterial toxin SopE.
Q27730215Structural basis for the specific interaction of lysine-containing proline-rich peptides with the N-terminal SH3 domain of c-Crk
Q27633082Structural basis for the thioredoxin-like activity profile of the glutaredoxin-like NrdH-redoxin from Escherichia coli
Q28914748Structural basis for unique mechanisms of folding and hemoglobin binding by a malarial protease
Q27758459Structural basis of 2C TCR allorecognition of H-2Ld peptide complexes
Q27635256Structural basis of HIV-1 and HIV-2 protease inhibition by a monoclonal antibody
Q46368503Structural basis of HutP-mediated anti-termination and roles of the Mg2+ ion and L-histidine ligand
Q27629148Structural basis of IAP recognition by Smac/DIABLO
Q27733164Structural basis of RNA folding and recognition in an AMP-RNA aptamer complex
Q27639792Structural basis of Rab effector specificity: crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A
Q24304419Structural basis of Rab5-Rabaptin5 interaction in endocytosis
Q47871496Structural basis of Redox-coupled protein substrate selection by the cytochrome c biosynthesis protein ResA.
Q27638917Structural basis of VDR-DNA interactions on direct repeat response elements
Q77350803Structural basis of activity and subunit recognition in G protein heterotrimers
Q27640373Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex
Q73711185Structural basis of allosteric changes in the GroEL mutant Arg197-->Ala
Q35623899Structural basis of asymmetry in the human immunodeficiency virus type 1 reverse transcriptase heterodimer
Q28570504Structural basis of biopterin-induced inhibition of GTP cyclohydrolase I by GFRP, its feedback regulatory protein
Q24290942Structural basis of caspase-7 inhibition by XIAP
Q27730408Structural basis of cell-cell adhesion by cadherins
Q24303332Structural basis of cellular redox regulation by human TRP14
Q27642551Structural basis of core promoter recognition in a primitive eukaryote
Q34403682Structural basis of eukaryotic nitrate reduction: crystal structures of the nitrate reductase active site
Q24557455Structural basis of filopodia formation induced by the IRSp53/MIM homology domain of human IRSp53
Q27638127Structural basis of gating by the outer membrane transporter FecA
Q27627995Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor
Q24336099Structural basis of hereditary coproporphyria.
Q27621769Structural basis of hyaluronan degradation by Streptococcus pneumoniae hyaluronate lyase
Q33840750Structural basis of mRNA cap recognition by proteins
Q27641849Structural basis of membrane binding by Gla domains of vitamin K-dependent proteins
Q47651331Structural basis of membrane targeting by the Phox homology domain of cytokine-independent survival kinase (CISK-PX).
Q27625365Structural basis of peptide binding and presentation by the type I diabetes-associated MHC class II molecule of NOD mice
Q27642660Structural basis of peptide-carbohydrate mimicry in an antibody-combining site
Q22010148Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1
Q27617260Structural basis of profactor D activation: from a highly flexible zymogen to a novel self-inhibited serine protease, complement factor D
Q34511593Structural basis of reduction-dependent activation of human cystatin F.
Q24802124Structural basis of regulation and substrate specificity of protein kinase CK2 deduced from the modeling of protein-protein interactions
Q27656910Structural basis of substrate specificity of plant 12-oxophytodienoate reductases
Q27654126Structural basis of tRNA modification with CO2 fixation and methylation by wybutosine synthesizing enzyme TYW4
Q27631209Structural basis of the Na+/H+ exchanger regulatory factor PDZ1 interaction with the carboxyl-terminal region of the cystic fibrosis transmembrane conductance regulator
Q35565448Structural basis of the abscess-modulating polysaccharide A2 from Bacteroides fragilis
Q28264126Structural basis of the alpha1-beta subunit interaction of voltage-gated Ca2+ channels
Q24598762Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain
Q27628766Structural basis of the recognition of the dishevelled DEP domain in the Wnt signaling pathway
Q27648304Structural basis of the zinc inhibition of human tissue kallikrein 5
Q27638985Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection
Q27643185Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Q27631960Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase
Q27625340Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily
Q34464071Structural biology of mycobacterial proteins: the Bangalore effort
Q37270148Structural characterization and comparative phylogenetic analysis of Escherichia coli HemK, a protein (N5)-glutamine methyltransferase
Q24297076Structural characterization of a novel Cbl phosphotyrosine recognition motif in the APS family of adapter proteins
Q44291856Structural characterization of mumps virus fusion protein core
Q73959951Structural characterization of the cysteine-rich domain of TFIIH p44 subunit
Q27628799Structural characterization of the human respiratory syncytial virus fusion protein core
Q33216321Structural characterization of the molecular platform for type III secretion system assembly.
Q43950624Structural characterizations of fusion peptide analogs of influenza virus hemagglutinin. Implication of the necessity of a helix-hinge-helix motif in fusion activity.
Q27732603Structural comparison between the d(CTAG) sequence in oligonucleotides and trp and met repressor-operator complexes
Q27639943Structural consequences of a cancer-causing BRCA1-BRCT missense mutation
Q43572388Structural consequences of site-directed mutagenesis in flexible protein domains: NMR characterization of the L(55,56)S mutant of RhoGDI.
Q27639578Structural conservation between the actin monomer-binding sites of twinfilin and actin-depolymerizing factor (ADF)/cofilin
Q27629136Structural control of polyketide formation in plant-specific polyketide synthases
Q36279666Structural coupling of the inhibitory regions flanking the ETS domain of murine Ets-1.
Q28119195Structural definition of the F-actin-binding THATCH domain from HIP1R
Q34006347Structural design of a eukaryotic DNA repair polymerase: DNA polymerase beta.
Q64069267Structural design principles that underlie the multi-specific interactions of Gα with dissimilar partners
Q27620814Structural details of an interaction between cardiolipin and an integral membrane protein
Q36321406Structural determinants for EB1-mediated recruitment of APC and spectraplakins to the microtubule plus end.
Q27642253Structural determinants of SecB recognition by SecA in bacterial protein translocation
Q27636062Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors
Q40468353Structural determinants of neurotrophin action.
Q27644663Structural determinants of nitroxide motion in spin-labeled proteins: Tertiary contact and solvent-inaccessible sites in helix G of T4 lysozyme
Q27730299Structural determinants of peptide-binding orientation and of sequence specificity in SH3 domains
Q27655429Structural determinants of product specificity of sucrose isomerases
Q44899756Structural determinants of substrate specificity in family 1 beta-glucosidases: novel insights from the crystal structure of sorghum dhurrinase-1, a plant beta-glucosidase with strict specificity, in complex with its natural substrate
Q24315151Structural determinants of the ADAM inhibition by TIMP-3: crystal structure of the TACE-N-TIMP-3 complex
Q33930355Structural determinants of tissue tropism and in vivo pathogenicity for the parvovirus minute virus of mice
Q42846855Structural determinants of trypsin affinity and specificity for cationic inhibitors
Q27643248Structural diversity in the six-fold redundant set of acyl-CoA carboxyltransferases in Mycobacterium tuberculosis
Q34350539Structural elements in IGP synthase exclude water to optimize ammonia transfer.
Q27760617Structural elements of an orphan nuclear receptor-DNA complex
Q27746348Structural evidence for a second sialic acid binding site in avian influenza virus neuraminidases
Q27620093Structural evidence for dimerization-regulated activation of an integral membrane phospholipase
Q27733411Structural evidence for specific S8-RNA and S8-protein interactions within the 30S ribosomal subunit: ribosomal protein S8 from Bacillus stearothermophilus at 1.9 A resolution
Q27640368Structural evidence for substrate strain in antibody catalysis
Q27766708Structural evidence of T cell xeno-reactivity in the absence of molecular mimicry
Q34226460Structural evidence that brain cyclic nucleotide phosphodiesterase is a member of the 2H phosphodiesterase superfamily
Q45110742Structural evidence that the 32-kilodalton lipoprotein (Tp32) of Treponema pallidum is an L-methionine-binding protein
Q27748907Structural features of halophilicity derived from the crystal structure of dihydrofolate reductase from the Dead Sea halophilic archaeon, Haloferax volcanii
Q27647913Structural features that stabilize halophilic malate dehydrogenase from an archaebacterium
Q28646141Structural fingerprints of the Ras-GTPase activating proteins neurofibromin and p120GAP
Q27642252Structural framework of fructosyl transfer in Bacillus subtilis levansucrase
Q24318542Structural framework of the GABARAP-calreticulin interface--implications for substrate binding to endoplasmic reticulum chaperones
Q27638461Structural genomics: A pipeline for providing structures for the biologist
Q47625382Structural genomics: bioinformatics in the driver's seat
Q35204026Structural genomics: computational methods for structure analysis
Q27758391Structural homologies with ATP- and folate-binding enzymes in the crystal structure of folylpolyglutamate synthetase
Q27642913Structural implications for heavy metal-induced reversible assembly and aggregation of a protein: the case of Pyrococcus horikoshii CutA
Q27642070Structural insight into modest binding of a non-PXXP ligand to the signal transducing adaptor molecule-2 Src homology 3 domain
Q24530532Structural insight into the complex formation of latent matrix metalloproteinase 2 with tissue inhibitor of metalloproteinase 2.
Q27647296Structural insight into the dual ligand specificity and mode of high density lipoprotein association of apolipoprotein D
Q27638457Structural insight into the mechanisms of targeting and signaling of focal adhesion kinase
Q74232718Structural insights into DNA polymerase beta fidelity: hold tight if you want it right
Q27642885Structural insights into molecular function of the metastasis-associated phosphatase PRL-3
Q57648104Structural insights into phosphoinositide 3-kinase catalysis and signalling
Q27636203Structural insights into steroid hormone binding: the crystal structure of a recombinant anti-testosterone Fab fragment in free and testosterone-bound forms
Q24681234Structural insights into the antigenicity of myelin oligodendrocyte glycoprotein
Q27633796Structural insights into the catalytic mechanism of a family 18 exo-chitinase
Q28273830Structural insights into the editing of germ-line-encoded interactions between T-cell receptor and MHC class II by Vα CDR3
Q24682124Structural insights into the innate immune recognition specificities of L- and H-ficolins
Q27619651Structural insights into the mechanism of intramolecular proteolysis
Q46493466Structural insights into the mechanism of nuclease A, a betabeta alpha metal nuclease from Anabaena.
Q27649467Structural insights into the substrate specificity and activity of ervatamins, the papain-like cysteine proteases from a tropical plant, Ervatamia coronaria
Q22011005Structural interactions of fibroblast growth factor receptor with its ligands
Q27631047Structural mechanism for rifampicin inhibition of bacterial rna polymerase
Q24316291Structural mechanism of Smad4 recognition by the nuclear oncoprotein Ski: insights on Ski-mediated repression of TGF-beta signaling
Q36756307Structural model of a complex between the heterotrimeric G protein, Gsalpha, and tubulin
Q34015845Structural models for the protein family characterized by gamete surface protein Pfs230 of Plasmodium falciparum
Q33487694Structural models of human eEF1A1 and eEF1A2 reveal two distinct surface clusters of sequence variation and potential differences in phosphorylation
Q35608734Structural plasticity and Mg2+ binding properties of RNase P P4 from combined analysis of NMR residual dipolar couplings and motionally decoupled spin relaxation
Q44505952Structural plasticity and the evolution of antibody affinity and specificity
Q28286455Structural predictions for the ligand-binding region of glycoprotein hormone receptors and the nature of hormone-receptor interactions
Q35606940Structural rearrangements in the membrane penetration protein of a non-enveloped virus
Q30381353Structural relationships among proteins with different global topologies and their implications for function annotation strategies
Q27737280Structural similarity between the pocket region of retinoblastoma tumour suppressor and the cyclin-box
Q37623098Structural similarity of YbeD protein from Escherichia coli to allosteric regulatory domains
Q27639441Structural snapshot of aberrant antigen presentation linked to autoimmunity: the immunodominant epitope of MBP complexed with I-Au
Q27646558Structural snapshots along the reaction pathway of ferredoxin-thioredoxin reductase
Q27936409Structural studies and mechanism of Saccharomyces cerevisiae dolichyl-phosphate-mannose synthase: insights into the initial step of synthesis of dolichyl-phosphate-linked oligosaccharide chains in membranes of endoplasmic reticulum
Q27637313Structural studies of the pigeon cytosolic NADP+-dependent malic enzyme
Q27640587Structural view of a fungal toxin acting on a 14-3-3 regulatory complex
Q27618579Structural view of the Ran-Importin beta interaction at 2.3 A resolution
Q27641990Structural, energetic, and functional analysis of a protein-protein interface at distinct stages of affinity maturation
Q35140088Structurally mapping the diverse phenotype of adeno-associated virus serotype 4.
Q90290722Structure Based Prediction of Neoantigen Immunogenicity
Q24316485Structure and Ca²⁺-binding properties of the tandem C₂ domains of E-Syt2
Q27641152Structure and Dynamics of the C-domain of Human Cardiac Troponin C in Complex with the Inhibitory Region of Human Cardiac Troponin I
Q27659237Structure and Filament Dynamics of the pSK41 Actin-like ParM Protein: IMPLICATIONS FOR PLASMID DNA SEGREGATION
Q27478377Structure and Function of Flavivirus NS5 Methyltransferase
Q27647161Structure and Sodium Channel Activity of an Excitatory I 1 -Superfamily Conotoxin † , ‡
Q28507100Structure and activity of the axon guidance protein MICAL
Q27640377Structure and allosteric regulation of the  X 2 integrin I domain
Q27640867Structure and assembly of an augmented Sm-like archaeal protein 14-mer
Q27628611Structure and assembly of the Alu domain of the mammalian signal recognition particle
Q24681481Structure and axon outgrowth inhibitor binding of the Nogo-66 receptor and related proteins
Q33937224Structure and biochemical analysis of a secretin pilot protein
Q33778048Structure and conformational flexibility of Candida rugosa lipase
Q27621238Structure and dimerization of a soluble form of B7-1
Q27617745Structure and dynamics in solution of the complex of lactobacillus casei dihydrofolate reductase with the new lipophilic antifolate drug trimetrexate
Q43623362Structure and dynamics of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase.
Q32067796Structure and dynamics of calmodulin in solution.
Q34302090Structure and dynamics of coxsackievirus B4 2A proteinase, an enyzme involved in the etiology of heart disease
Q27643183Structure and dynamics of the nucleocapsid-binding domain of the Sendai virus phosphoprotein in solution
Q34177305Structure and dynamics of zymogen human blood coagulation factor X
Q27639390Structure and flexibility of Streptococcus agalactiae hyaluronate lyase complex with its substrate. Insights into the mechanism of processive degradation of hyaluronan
Q27627450Structure and function of Cdc6/Cdc18: implications for origin recognition and checkpoint control
Q36879883Structure and function of alpha-tocopherol transfer protein: implications for vitamin E metabolism and AVED.
Q27640539Structure and function of an archaeal homolog of survival protein E (SurEalpha): an acid phosphatase with purine nucleotide specificity
Q37015009Structure and function of human plasma carboxypeptidase N, the anaphylatoxin inactivator
Q34017802Structure and function of laminin LG modules
Q27653658Structure and function of the 5′→3′ exoribonuclease Rat1 and its activating partner Rai1
Q24635302Structure and function of the C-terminal PABC domain of human poly(A)-binding protein
Q45100697Structure and function of the C-terminal domain of the polymerase cofactor of rabies virus
Q38318788Structure and function of the N-linked glycans of HBP/CAP37/azurocidin: crystal structure determination and biological characterization of nonglycosylated HBP.
Q27638973Structure and functional interactions of the Tsg101 UEV domain
Q27639693Structure and inactivation of triosephosphate isomerase from Entamoeba histolytica
Q27664231Structure and inhibition of herpesvirus DNA packaging terminase nuclease domain
Q27633813Structure and ligand recognition of the PB1 domain: a novel protein module binding to the PC motif
Q24303575Structure and ligand-induced conformational change of the 39-kDa glycoprotein from human articular chondrocytes
Q27621861Structure and mechanism of 3-deoxy-D-manno-octulosonate 8-phosphate synthase
Q27937235Structure and mechanism of ADP-ribose-1''-monophosphatase (Appr-1''-pase), a ubiquitous cellular processing enzyme
Q27732221Structure and mechanism of DNA topoisomerase II
Q35718381Structure and mechanism of NAD[P]H:quinone acceptor oxidoreductases (NQO).
Q27640367Structure and mechanism of a coreceptor for infection by a pathogenic feline retrovirus
Q27746075Structure and mechanism of endo/exocellulase E4 from Thermomonospora fusca
Q27662730Structure and mechanism of human DNA polymerase η
Q27642985Structure and mechanism of mRNA cap (guanine-N7) methyltransferase
Q33803876Structure and mechanism of proton-translocating transhydrogenase.
Q27631738Structure and mechanism of the RNA triphosphatase component of mammalian mRNA capping enzyme
Q24300049Structure and mechanism of the phosphotyrosyl phosphatase activator
Q27620618Structure and mechanism of yeast RNA triphosphatase: an essential component of the mRNA capping apparatus
Q24537053Structure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14
Q34348303Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope
Q27650001Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms
Q35606828Structure and molecular mechanism of Bacillus anthracis cofactor-independent phosphoglycerate mutase: a crucial enzyme for spores and growing cells of Bacillus species
Q27766337Structure and mutagenesis of the Dbl homology domain
Q27642533Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain
Q24294357Structure and phosphatidylinositol-(3,4)-bisphosphate binding of the C-terminal PH domain of human pleckstrin
Q27635171Structure and regulation of the CDK5-p25(nck5a) complex
Q34103328Structure and regulatory interactions of the cytoplasmic terminal domains of serotonin transporter.
Q27765991Structure and specificity of nuclear receptor-coactivator interactions
Q27730219Structure and specificity of the anti-digoxin antibody 40-50
Q27642408Structure and stability of the ankyrin domain of the Drosophila Notch receptor
Q34187846Structure and transport mechanism of the bacterial oxalate transporter OxlT
Q59312685Structure at 1.3Å Resolution of Rhodothermus marinus caa3 Cytochrome c Domain
Q27639154Structure at 1.9 A resolution of a quinohemoprotein alcohol dehydrogenase from Pseudomonas putida HK5
Q27730864Structure at 2.8 A resolution of F1-ATPase from bovine heart mitochondria
Q31163835Structure basis and unconventional lipid membrane binding properties of the PH-C1 tandem of rho kinases
Q27737190Structure determination of yeast cofilin
Q27647639Structure of Adeno-Associated Virus Serotype 8, a Gene Therapy Vector
Q27651375Structure of AscE and induced burial regions in AscE and AscG upon formation of the chaperone needle-subunit complex of type III secretion system inAeromonas hydrophila
Q27625226Structure of BamHI bound to nonspecific DNA: a model for DNA sliding
Q27639369Structure of CcmG/DsbE at 1.14 A resolution: high-fidelity reducing activity in an indiscriminately oxidizing environment
Q27641799Structure of E. coli ketopantoate hydroxymethyl transferase complexed with ketopantoate and Mg2+, solved by locating 160 selenomethionine sites
Q27624939Structure of GATE-16, membrane transport modulator and mammalian ortholog of autophagocytosis factor Aut7p
Q24792070Structure of GlgS from Escherichia coli suggests a role in protein-protein interactions
Q27632602Structure of Golgi alpha-mannosidase II: a target for inhibition of growth and metastasis of cancer cells
Q27644824Structure of GrlR and the Implication of Its EDED Motif in Mediating the Regulation of Type III Secretion System in EHEC
Q27735437Structure of HBP, a multifunctional protein with a serine proteinase fold
Q27644478Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9
Q27621387Structure of Hsp15 reveals a novel RNA-binding motif
Q27638968Structure of NF-kappaB p50/p65 heterodimer bound to the PRDII DNA element from the interferon-beta promoter
Q27641937Structure of NFAT1 bound as a dimer to the HIV-1 LTR kappa B element
Q27648857Structure of Natural Killer Receptor 2B4 Bound to CD48 Reveals Basis for Heterophilic Recognition in Signaling Lymphocyte Activation Molecule Family
Q42651682Structure of P-protein of the glycine cleavage system: implications for nonketotic hyperglycinemia
Q35950620Structure of PIN-domain protein PH0500 from Pyrococcus horikoshii
Q27631594Structure of Pumilio reveals similarity between RNA and peptide binding motifs
Q83177151Structure of RhlG, an essential beta-ketoacyl reductase in the rhamnolipid biosynthetic pathway of Pseudomonas aeruginosa
Q27735387Structure of Semliki Forest virus core protein
Q27641911Structure of Swine Vesicular Disease Virus: Mapping of Changes Occurring during Adaptation of Human Coxsackie B5 Virus To Infect Swine
Q56603096Structure of Type IIβ Phosphatidylinositol Phosphate Kinase
Q27729753Structure of a 14-3-3 protein and implications for coordination of multiple signalling pathways
Q24337578Structure of a Bmi-1-Ring1B polycomb group ubiquitin ligase complex
Q27663610Structure of a C-terminal fragment of its Vps53 subunit suggests similarity of Golgi-associated retrograde protein (GARP) complex to a family of tethering complexes
Q27617465Structure of a DNA-bound Ultrabithorax-Extradenticle homeodomain complex
Q27642327Structure of a Delivery Protein for an AAA+ Protease in Complex with a Peptide Degradation Tag
Q27628296Structure of a PH domain from the C. elegans muscle protein UNC-89 suggests a novel function
Q27652517Structure of a Protein Phosphatase 2A Holoenzyme: Insights into B55-Mediated Tau Dephosphorylation
Q27617536Structure of a Ran-binding domain complexed with Ran bound to a GTP analogue: implications for nuclear transport
Q27639929Structure of a T7 RNA polymerase elongation complex at 2.9 A resolution
Q46886569Structure of a [2Fe-2S] ferredoxin from Rhodobacter capsulatus likely involved in Fe-S cluster biogenesis and conformational changes observed upon reduction.
Q27639211Structure of a beta-alanine-linked polyamide bound to a full helical turn of purine tract DNA in the 1:1 motif
Q27626747Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases
Q24321126Structure of a cell polarity regulator, a complex between atypical PKC and Par6 PB1 domains
Q27738974Structure of a cholesterol-binding, thiol-activated cytolysin and a model of its membrane form
Q27622544Structure of a conserved domain common to the transcription factors TFIIS, elongin A, and CRSP70
Q27627794Structure of a covalently stabilized complex of a human alphabeta T-cell receptor, influenza HA peptide and MHC class II molecule, HLA-DR1
Q27733371Structure of a dehydratase-isomerase from the bacterial pathway for biosynthesis of unsaturated fatty acids: two catalytic activities in one active site
Q27630591Structure of a flavin-binding plant photoreceptor domain: Insights into light-mediated signal transduction
Q27638084Structure of a functional IGF2R fragment determined from the anomalous scattering of sulfur
Q27640464Structure of a gametocyte protein essential for sexual development in Plasmodium falciparum
Q43018765Structure of a halophilic nucleoside diphosphate kinase from Halobacterium salinarum.
Q27760195Structure of a heparin-linked biologically active dimer of fibroblast growth factor
Q22010160Structure of a heterophilic adhesion complex between the human CD2 and CD58 (LFA-3) counterreceptors
Q24617306Structure of a human ASF1a-HIRA complex and insights into specificity of histone chaperone complex assembly
Q45696228Structure of a knockout mutant of influenza virus M1 protein that has altered activities in membrane binding, oligomerisation and binding to NEP (NS2).
Q27633847Structure of a legume lectin from the bark of Robinia pseudoacacia and its complex with N-acetylgalactosamine
Q24816484Structure of a pheromone receptor-associated MHC molecule with an open and empty groove
Q27628781Structure of a rat α1-macroglobulin receptor-binding domain dimer
Q27628883Structure of a sialic acid-activating synthetase, CMP-acylneuraminate synthetase in the presence and absence of CDP
Q27649234Structure of a site-2 protease family intramembrane metalloprotease
Q27760646Structure of a snake venom phospholipase A2 modified by p-bromo-phenacyl-bromide
Q27620087Structure of a soluble secreted chemokine inhibitor vCCI (p35) from cowpox virus
Q24324349Structure of a specific peptide complex of the carboxy-terminal SH2 domain from the p85 alpha subunit of phosphatidylinositol 3-kinase
Q27639620Structure of a tRNA repair enzyme and molecular biology workhorse: T4 polynucleotide kinase
Q27657691Structure of a tRNA-dependent kinase essential for selenocysteine decoding
Q27641607Structure of a trapped endonuclease III-DNA covalent intermediate
Q42661328Structure of a trimeric domain of the MHC class II-associated chaperonin and targeting protein Ii.
Q27658371Structure of a two-G-tetrad intramolecular G-quadruplex formed by a variant human telomeric sequence in K+ solution: insights into the interconversion of human telomeric G-quadruplex structures
Q27636829Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein
Q27618988Structure of a voltage-dependent K+ channel beta subunit
Q27733259Structure of a water soluble fragment of the 'Rieske' iron-sulfur protein of the bovine heart mitochondrial cytochrome bc1 complex determined by MAD phasing at 1.5 A resolution
Q34341088Structure of adeno-associated virus type 2 Rep40-ADP complex: insight into nucleotide recognition and catalysis by superfamily 3 helicases
Q27765157Structure of an Fab fragment against a C-terminal peptide of hCG at 2.0 A resolution
Q27759364Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody
Q22008582Structure of an IkappaBalpha/NF-kappaB complex
Q24533379Structure of an XRCC1 BRCT domain: a new protein-protein interaction module
Q44821895Structure of an activated Dictyostelium STAT in its DNA-unbound form
Q27636743Structure of an archaeal homolog of the eukaryotic RNA polymerase II RPB4/RPB7 complex
Q24295189Structure of an ultraweak protein-protein complex and its crucial role in regulation of cell morphology and motility
Q27634493Structure of apoptosis-linked protein ALG-2: insights into Ca2+-induced changes in penta-EF-hand proteins
Q27621811Structure of basic phospholipase A2 from Agkistrodon halys Pallas: implications for its association, hemolytic and anticoagulant activities
Q27732553Structure of beta 2-bungarotoxin: potassium channel binding by Kunitz modules and targeted phospholipase action
Q27637085Structure of cephalosporin acylase in complex with glutaryl-7-aminocephalosporanic acid and glutarate: insight into the basis of its substrate specificity
Q27644622Structure of colicin I receptor bound to the R-domain of colicin Ia: implications for protein import
Q27639290Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra alpha-helical domain
Q27634982Structure of crystalline D-Tyr-tRNA(Tyr) deacylase. A representative of a new class of tRNA-dependent hydrolases
Q27733735Structure of crystalline Escherichia coli methionyl-tRNA(f)Met formyltransferase: comparison with glycinamide ribonucleotide formyltransferase
Q27639696Structure of domain III of the blood-stage malaria vaccine candidate, Plasmodium falciparum apical membrane antigen 1 (AMA1)
Q27637386Structure of equine infectious anemia virus matrix protein
Q24539197Structure of eukaryotic prefoldin and of its complexes with unfolded actin and the cytosolic chaperonin CCT.
Q27638483Structure of formamidopyrimidine-DNA glycosylase covalently complexed to DNA
Q27729833Structure of guanine-nucleotide-exchange factor human Mss4 and identification of its Rab-interacting surface
Q35198020Structure of human ACE gives new insights into inhibitor binding and design
Q24621648Structure of human DNMT2, an enigmatic DNA methyltransferase homolog that displays denaturant-resistant binding to DNA
Q28115103Structure of human MTH1, a Nudix family hydrolase that selectively degrades oxidized purine nucleoside triphosphates
Q24313581Structure of human brain fructose 1,6-(bis)phosphate aldolase: linking isozyme structure with function
Q27730703Structure of human chorionic gonadotropin at 2.6 A resolution from MAD analysis of the selenomethionyl protein
Q27636471Structure of human dipeptidyl peptidase I (cathepsin C): exclusion domain added to an endopeptidase framework creates the machine for activation of granular serine proteases
Q27640807Structure of human estrone sulfatase suggests functional roles of membrane association
Q27621403Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins
Q24671977Structure of human histocompatibility leukocyte antigen (HLA)-Cw4, a ligand for the KIR2D natural killer cell inhibitory receptor
Q42143533Structure of human salivary alpha-amylase crystallized in a C-centered monoclinic space group
Q27618407Structure of importin-beta bound to the IBB domain of importin-alpha
Q27618764Structure of mammalian ornithine decarboxylase at 1.6 A resolution: stereochemical implications of PLP-dependent amino acid decarboxylases
Q27639500Structure of methylene-tetrahydromethanopterin dehydrogenase from methylobacterium extorquens AM1
Q27642491Structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside
Q27746561Structure of mouse 7S NGF: a complex of nerve growth factor with four binding proteins
Q27630616Structure of neurolysin reveals a deep channel that limits substrate access
Q46523648Structure of oxidized alpha-haemoglobin bound to AHSP reveals a protective mechanism for haem
Q24307934Structure of protein phosphatase 2A core enzyme bound to tumor-inducing toxins
Q27739964Structure of pvu II DNA-(cytosine N4) methyltransferase, an example of domain permutation and protein fold assignment
Q27733264Structure of rat procathepsin B: model for inhibition of cysteine protease activity by the proregion
Q27734832Structure of recombinant human CPP32 in complex with the tetrapeptide acetyl-Asp-Val-Ala-Asp fluoromethyl ketone
Q27625236Structure of small virus-like particles assembled from the L1 protein of human papillomavirus 16
Q27765278Structure of the ATP-dependent oligomerization domain of N-ethylmaleimide sensitive factor complexed with ATP
Q27626886Structure of the ArsA ATPase: the catalytic subunit of a heavy metal resistance pump
Q29031393Structure of the BRCT Repeats of BRCA1 Bound to a BACH1 Phosphopeptide
Q27619329Structure of the C-terminal domain of FliG, a component of the rotor in the bacterial flagellar motor
Q24678778Structure of the C-terminal domain of Tup1, a corepressor of transcription in yeast
Q27640198Structure of the C-terminal domains of merozoite surface protein-1 from Plasmodium knowlesi reveals a novel histidine binding site
Q24630865Structure of the C-terminal laminin G-like domain pair of the laminin alpha2 chain harbouring binding sites for alpha-dystroglycan and heparin
Q27733704Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA
Q39751684Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans
Q27629218Structure of the Ca2+-regulated photoprotein obelin at 1.7 Å resolution determined directly from its sulfur substructure
Q24294734Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex
Q27639953Structure of the DNA binding region of prospero reveals a novel homeo-prospero domain
Q27748936Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA
Q27638053Structure of the Epstein-Barr virus gp42 protein bound to the MHC class II receptor HLA-DR1
Q27620240Structure of the Escherichia coli TolB protein determined by MAD methods at 1.95 A resolution
Q27653463Structure of the F-spondin domain of mindin, an integrin ligand and pattern recognition molecule
Q27733279Structure of the FGF receptor tyrosine kinase domain reveals a novel autoinhibitory mechanism
Q27625567Structure of the Fc fragment of human IgE bound to its high-affinity receptor Fc epsilonRI alpha
Q27622377Structure of the Homer EVH1 domain-peptide complex reveals a new twist in polyproline recognition
Q27646647Structure of the Hybrid-2 type intramolecular human telomeric G-quadruplex in K+ solution: insights into structure polymorphism of the human telomeric sequence
Q34381905Structure of the IRS-1 PTB domain bound to the juxtamembrane region of the insulin receptor
Q27634006Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair
Q27640067Structure of the LDL receptor extracellular domain at endosomal pH
Q27643166Structure of the La motif: a winged helix domain mediates RNA binding via a conserved aromatic patch
Q24314763Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain
Q24791167Structure of the Mg-chelatase cofactor GUN4 reveals a novel hand-shaped fold for porphyrin binding
Q57752679Structure of the N-terminal domain of PEX1 AAA-ATPase. Characterization of a putative adaptor-binding domain
Q24656151Structure of the Na,K-ATPase regulatory protein FXYD1 in micelles
Q24646827Structure of the Neurospora SET domain protein DIM-5, a histone H3 lysine methyltransferase
Q56690326Structure of the Nogo Receptor Ectodomain
Q24532248Structure of the PH domain and Btk motif from Bruton's tyrosine kinase: molecular explanations for X-linked agammaglobulinaemia
Q24290654Structure of the PHD zinc finger from human Williams-Beuren syndrome transcription factor
Q27649148Structure of the Pho85-Pho80 CDK-Cyclin Complex of the Phosphate-Responsive Signal Transduction Pathway
Q27678432Structure of the Plasmodium 6-cysteine s48/45 domain
Q56803043Structure of the RGS-like Domain from PDZ-RhoGEF
Q27621610Structure of the RXR-RAR DNA-binding complex on the retinoic acid response element DR1
Q27743813Structure of the Ras-binding domain of RalGEF and implications for Ras binding and signalling
Q27641676Structure of the Rho transcription terminator: mechanism of mRNA recognition and helicase loading
Q27644202Structure of the SARS coronavirus nucleocapsid protein RNA-binding dimerization domain suggests a mechanism for helical packaging of viral RNA
Q27639671Structure of the Sec23/24-Sar1 pre-budding complex of the COPII vesicle coat
Q27628646Structure of the TPR domain of p67phox in complex with Rac.GTP
Q27628323Structure of the Tie2 RTK domain: self-inhibition by the nucleotide binding loop, activation loop, and C-terminal tail
Q27732673Structure of the UmuD' protein and its regulation in response to DNA damage
Q30176860Structure of the WW domain of a kinase-associated protein complexed with a proline-rich peptide.
Q27625176Structure of the active core of human stem cell factor and analysis of binding to its receptor Kit
Q27619597Structure of the alpha-actinin rod: molecular basis for cross-linking of actin filaments
Q27617539Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase
Q28245105Structure of the apoptotic protease-activating factor 1 bound to ADP
Q27638714Structure of the bacterial RNA polymerase promoter specificity sigma subunit
Q27641896Structure of the bacteriophage T4 DNA adenine methyltransferase
Q42039270Structure of the beta 2 homodimer of bacterial luciferase from Vibrio harveyi: X-ray analysis of a kinetic protein folding trap
Q33998447Structure of the biologically relevant G-quadruplex in the c-MYC promoter
Q27640679Structure of the catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase
Q27621773Structure of the central core domain of TFIIEbeta with a novel double-stranded DNA-binding surface
Q33886560Structure of the chromatin binding (chromo) domain from mouse modifier protein 1.
Q27641268Structure of the coat protein in fd filamentous bacteriophage particles determined by solid-state NMR spectroscopy
Q27729423Structure of the complex between the Fab fragment of a neutralizing antibody for type 1 poliovirus and its viral epitope
Q27748129Structure of the complex of leech-derived tryptase inhibitor (LDTI) with trypsin and modeling of the LDTI-tryptase system
Q37208358Structure of the conserved core of the yeast Dot1p, a nucleosomal histone H3 lysine 79 methyltransferase
Q33339927Structure of the conserved domain of ANAC, a member of the NAC family of transcription factors
Q27625246Structure of the cytoplasmic beta subunit-T1 assembly of voltage-dependent K+ channels
Q27625369Structure of the dimerized hormone-binding domain of a guanylyl-cyclase-coupled receptor
Q27732388Structure of the even-skipped homeodomain complexed to AT-rich DNA: new perspectives on homeodomain specificity
Q27640083Structure of the extracellular domains of the human interleukin-6 receptor alpha -chain
Q42151087Structure of the foot-and-mouth disease virus leader protease: a papain-like fold adapted for self-processing and eIF4G recognition
Q24648836Structure of the fungal beta-glucan-binding immune receptor dectin-1: implications for function
Q27631384Structure of the gating domain of a Ca2+-activated K+ channel complexed with Ca2+/calmodulin
Q27633789Structure of the gene 2.5 protein, a single-stranded DNA binding protein encoded by bacteriophage T7
Q27631654Structure of the globular region of the prion protein Ure2 from the yeast Saccharomyces cerevisiae
Q28262821Structure of the guanine nucleotide exchange factor Sec7 domain of human arno and analysis of the interaction with ARF GTPase
Q27766027Structure of the haemagglutinin-esterase-fusion glycoprotein of influenza C virus
Q27644373Structure of the human GINS complex and its assembly and functional interface in replication initiation
Q27627340Structure of the human IgE-Fc C epsilon 3-C epsilon 4 reveals conformational flexibility in the antibody effector domains
Q34189676Structure of the inhibitory region of troponin by site directed spin labeling electron paramagnetic resonance
Q27652388Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2
Q27644282Structure of the intramolecular human telomeric G-quadruplex in potassium solution: a novel adenine triple formation
Q27765101Structure of the key toxin in gas gangrene
Q27641538Structure of the male determinant factor for Brassica self-incompatibility
Q45015300Structure of the molybdopterin-bound Cnx1G domain links molybdenum and copper metabolism.
Q27639744Structure of the neutrophil-activating protein from Helicobacter pylori
Q22009923Structure of the nuclear transport complex karyopherin-beta2-Ran x GppNHp
Q33714512Structure of the nucleotide complex of PyrR, the pyr attenuation protein from Bacillus caldolyticus, suggests dual regulation by pyrimidine and purine nucleotides.
Q54499897Structure of the periplasmic chaperone Skp suggests functional similarity with cytosolic chaperones despite differing architecture.
Q34339402Structure of the photolyase-like domain of cryptochrome 1 from Arabidopsis thaliana
Q34342817Structure of the pleckstrin homology domain from beta-spectrin.
Q27766029Structure of the protein kinase Cbeta phospholipid-binding C2 domain complexed with Ca2+
Q24337251Structure of the protein phosphatase 2A holoenzyme
Q27622391Structure of the reovirus core at 3.6 A resolution
Q27637699Structure of the reovirus membrane-penetration protein, Mu1, in a complex with is protector protein, Sigma3
Q27630251Structure of the reovirus outer capsid and dsRNA-binding protein sigma3 at 1.8 A resolution
Q27641342Structure of the replicative helicase of the oncoprotein SV40 large tumour antigen
Q27639150Structure of the retinal determination protein Dachshund reveals a DNA binding motif
Q27620906Structure of the soluble domain of cytochrome c(552) from Paracoccus denitrificans in the oxidized and reduced states
Q37714099Structure of the streptococcal endopeptidase IdeS, a cysteine proteinase with strict specificity for IgG.
Q27641998Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187
Q27636650Structure of the type III secretion and substrate-binding domain of Yersinia YopH phosphatase
Q27621683Structure of the winged-helix protein hRFX1 reveals a new mode of DNA binding
Q24672310Structure of tick anticoagulant peptide at 1.6 A resolution complexed with bovine pancreatic trypsin inhibitor
Q27743943Structure of translation factor eIF4E bound to m7GDP and interaction with 4E-binding protein
Q27636055Structure of trichodiene synthase from Fusarium sporotrichioides provides mechanistic inferences on the terpene cyclization cascade
Q38342431Structure of uPAR, plasminogen, and sugar-binding sites of the 300 kDa mannose 6-phosphate receptor
Q34829635Structure of vaccinia complement protein in complex with heparin and potential implications for complement regulation
Q27684849Structure of  -galactosidase at 3.2-A resolution obtained by cryo-electron microscopy
Q38339608Structure prediction of a complex between the chromosomal protein HMG-D and DNA.
Q27644071Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphism
Q34991803Structure, binding, and antagonists in the IL-4/IL-13 receptor system.
Q24522550Structure--function relationships in HIV-1 Nef.
Q57206146Structure-Based Development of Anticancer Drugs
Q24798825Structure-based analysis of the ultraspiracle protein and docking studies of putative ligands
Q28202603Structure-based design of aliskiren, a novel orally effective renin inhibitor
Q28376938Structure-based design of non-nucleoside reverse transcriptase inhibitors of drug-resistant human immunodeficiency virus
Q27625444Structure-based drug design: the discovery of novel nonpeptide orally active inhibitors of human renin
Q41004311Structure-based minimization of transforming growth factor-alpha (TGF-alpha) through NMR analysis of the receptor-bound ligand. Design, solution structure, and activity of TGF-alpha 8-50.
Q39593385Structure-based moloney murine leukemia virus reverse transcriptase mutants with altered intracellular direct-repeat deletion frequencies
Q73039693Structure-based sequence alignment for the beta-trefoil subdomain of the clostridial neurotoxin family provides residue level information about the putative ganglioside binding site
Q36280511Structure-based subsite specificity mapping of human cathepsin D using statine-based inhibitors
Q42135710Structure-based thermodynamic analysis of the dissociation of protein phosphatase-1 catalytic subunit and microcystin-LR docked complexes
Q50136424Structure-directed discovery of potent non-peptidic inhibitors of human urokinase that access a novel binding subsite.
Q77754835Structure-function analyses of the ATX1 metallochaperone
Q27760215Structure-function analysis of cell adhesion by neural (N-) cadherin
Q40635854Structure-function analysis of reovirus binding to junctional adhesion molecule 1. Implications for the mechanism of reovirus attachment
Q44768460Structure-function analysis of the reactive site in the first Kunitz-type domain of human tissue factor pathway inhibitor-2.
Q27638407Structure-function relationship of three neurotoxins from the venom of Naja kaouthia: a comparison between the NMR-derived structure of NT2 with its homologues, NT1 and NT3
Q73883707Structure-function relationships in Drosophila melanogaster alcohol dehydrogenase allozymes ADH(S), ADH(F) and ADH(UF), and distantly related forms
Q34367650Structure-function relationships of beta-D-glucan endo- and exohydrolases from higher plants
Q24307685Structure-function studies of the G-domain from human gem, a novel small G-protein
Q27641193Structure-guided design of sialic acid-based Siglec inhibitors and crystallographic analysis in complex with sialoadhesin
Q45416737Structures and polymorphic interactions of two heptad-repeat regions of the SARS virus S2 protein
Q30155843Structures of Anabaena calcium-binding protein CcbP: insights into Ca2+ signaling during heterocyst differentiation
Q44976541Structures of Bacillus subtilis PdaA, a family 4 carbohydrate esterase, and a complex with N-acetyl-glucosamine
Q27629806Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates
Q27621351Structures of human dihydroorotate dehydrogenase in complex with antiproliferative agents
Q27643055Structures of isobutyryl-CoA dehydrogenase and enzyme-product complex: comparison with isovaleryl- and short-chain acyl-CoA dehydrogenases
Q27649470Structures of open (R) and close (T) states of prephenate dehydratase (PDT)—Implication of allosteric regulation by l-phenylalanine
Q27640697Structures of shikimate dehydrogenase AroE and its Paralog YdiB. A common structural framework for different activities
Q24338548Structures of the SUMO E1 provide mechanistic insights into SUMO activation and E2 recruitment to E1
Q27640304Structures of the alpha L I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation
Q27938892Structures of the carbohydrate recognition domain of Ca2+-independent cargo receptors Emp46p and Emp47p
Q27639344Structures of the complexes of a potent anti-HIV protein cyanovirin-N and high mannose oligosaccharides
Q24536928Structures of the pleiotropic translational regulator Hfq and an Hfq-RNA complex: a bacterial Sm-like protein
Q27641681Structures of thermophilic and mesophilic adenylate kinases from the genus Methanococcus
Q27631706Structures of tryparedoxins revealing interaction with trypanothione
Q33934401Structures of two core subunits of the bacterial type IV secretion system, VirB8 from Brucella suis and ComB10 from Helicobacter pylori
Q27619595Structures of two repeats of spectrin suggest models of flexibility
Q27639002Structures of two streptococcal superantigens bound to TCR beta chains reveal diversity in the architecture of T cell signaling complexes
Q27634686Structures of yeast ARF2 and ARL1: distinct roles for the N terminus in the structure and function of ARF family GTPases
Q27643926Studies ofToxoplasma gondiiandPlasmodium falciparumenoyl acyl carrier protein reductase and implications for the development of antiparasitic agents
Q24657643Studies on the interactions between human replication factor C and human proliferating cell nuclear antigen
Q37461059Studying the role of cooperative hydration in stabilizing folded protein states
Q47828186Substituting nonpeptidic spacers for the T cell receptor-binding part of class I major histocompatibility complex-binding peptides.
Q52073005Substitutions of surface amino acid residues of cutinase probed by aqueous two-phase partitioning.
Q27628921Substrate and metal complexes of 3-deoxy-D-manno-octulosonate-8-phosphate synthase from Aquifex aeolicus at 1.9-A resolution. Implications for the condensation mechanism
Q57753139Substrate binding and catalytic mechanism of a barley beta-D-Glucosidase/(1,4)-beta-D-glucan exohydrolase
Q34510672Substrate envelope and drug resistance: crystal structure of RO1 in complex with wild-type human immunodeficiency virus type 1 protease
Q27640290Substrate recognition and molecular mechanism of fatty acid hydroxylation by cytochrome P450 from Bacillus subtilis. Crystallographic, spectroscopic, and mutational studies
Q22253457Substrate recognition by the Lyn protein-tyrosine kinase. NMR structure of the immunoreceptor tyrosine-based activation motif signaling region of the B cell antigen receptor
Q27638967Substrate shape determines specificity of recognition for HIV-1 protease: analysis of crystal structures of six substrate complexes
Q46201441Substrate specificity and catalytic mechanism of a xyloglucan xyloglucosyl transferase HvXET6 from barley (Hordeum vulgare L.).
Q56896763Substrate specificity of prostate-specific antigen (PSA)
Q24531411Subunit H of the V-ATPase involved in endocytosis shows homology to beta-adaptins
Q27618799Sulfolobus acidocaldariusinorganic pyrophosphatase: Structure, thermostability, and effect of metal ion in an archael pyrophosphatase
Q73902403Surface and electrostatics of cutinases
Q40473008Surface charge and hydrophobicity determine ErbB2 binding to the Hsp90 chaperone complex.
Q52229473Surface properties of adipocyte lipid-binding protein: Response to lipid binding, and comparison with homologous proteins.
Q59081293Surface topography dependence of biomolecular hydrophobic hydration
Q90400839Survivin polymorphisms and susceptibility to prostate cancer: A genetic association study and an in silico analysis
Q28302242Synaptotagmin-syntaxin interaction: the C2 domain as a Ca2+-dependent electrostatic switch
Q27635182T cell activity correlates with oligomeric peptide-major histocompatibility complex binding on T cell surface
Q27681162TFIID TAF6-TAF9 Complex Formation Involves the HEAT Repeat-containing C-terminal Domain of TAF6 and Is Modulated by TAF5 Protein
Q42870917TRIFORCE: Tessellated Semianalytical Solvent Exposed Surface Areas and Derivatives
Q27618088Tachylectin-2: crystal structure of a specific GlcNAc/GalNAc-binding lectin involved in the innate immunity host defense of the Japanese horseshoe crab Tachypleus tridentatus
Q27652908Targeting Inactive Enzyme Conformation: Aryl Diketoacid Derivatives as a New Class of PTP1B Inhibitors
Q42847608Temperature-sensitive suppressor mutations of the Escherichia coli DNA gyrase B protein
Q51143192Template-assisted extrusion of biopolymer nanofibers under physiological conditions.
Q27469313Template/primer requirements and single nucleotide incorporation by hepatitis C virus nonstructural protein 5B polymerase
Q28768510Terminating eukaryote translation: domain 1 of release factor eRF1 functions in stop codon recognition
Q27732905Tertiary structure of destrin and structural similarity between two actin-regulating protein families
Q71921244Tertiary structure of uracil-DNA glycosylase inhibitor protein
Q34504588Text Mining for Protein Docking
Q33957289The "tale" of UmuD and its role in SOS mutagenesis
Q27733265The 1.1 A crystal structure of the neuronal acetylcholine receptor antagonist, alpha-conotoxin PnIA from Conus pennaceus
Q45985430The 1.1-angstrom structure of the spindle checkpoint protein Bub3p reveals functional regions.
Q27621203The 1.5 A crystal structure of a bleomycin resistance determinant from bleomycin-producing Streptomyces verticillus
Q27733207The 1.5-A resolution crystal structure of bacterial luciferase in low salt conditions
Q27640637The 1.6-A crystal structure of the class of chaperones represented by Escherichia coli Hsp31 reveals a putative catalytic triad
Q27639378The 1.62 A structure of Thermoascus aurantiacus endoglucanase: completing the structural picture of subfamilies in glycoside hydrolase family 5
Q28910356The 1.8-A crystal structure of human tear lipocalin reveals an extended branched cavity with capacity for multiple ligands
Q27732664The 1.85 A structure of vaccinia protein VP39: a bifunctional enzyme that participates in the modification of both mRNA ends
Q27639246The 1.9 A crystal structure of heat-labile shrimp alkaline phosphatase
Q27638971The 1.9 A structure of alpha-N-acetylgalactosaminidase: molecular basis of glycosidase deficiency diseases
Q27732250The 2.0 A crystal structure of a heterotrimeric G protein
Q27738757The 2.1-A crystal structure of an archaeal preinitiation complex: TATA-box-binding protein/transcription factor (II)B core/TATA-box
Q57721635The 2.2 Å Crystal Structure of Hsp33
Q27618047The 2.8 A crystal structure of visual arrestin: a model for arrestin's regulation
Q27735465The 2.8 A structure of hydroxylamine oxidoreductase from a nitrifying chemoautotrophic bacterium, Nitrosomonas europaea
Q27748974The 3-D structure of a folate-dependent dehydrogenase/cyclohydrolase bifunctional enzyme at 1.5 A resolution
Q38333892The ABC maltose transporter
Q34233279The AidB component of the Escherichia coli adaptive response to alkylating agents is a flavin-containing, DNA-binding protein
Q58561298The Associative Properties of Some Amphiphilic Fullerene Derivatives
Q24673162The BPI/LBP family of proteins: a structural analysis of conserved regions
Q33914275The BRCA1 C-terminal domain: structure and function.
Q56970136The Biomolecular Interface as a Selectivity Filter for Drug-Based Targeted Therapy
Q33904609The C-terminal domain of DNA gyrase A adopts a DNA-bending beta-pinwheel fold
Q54561820The C-terminal domain of TolA is the coreceptor for filamentous phage infection of E. coli.
Q27650593The C. elegans SYS-1 Protein Is a Bona Fide β-Catenin
Q59647662The COOH Terminus of Aminoglycoside Phosphotransferase (3′)-IIIa Is Critical for Antibiotic Recognition and Resistance
Q27653315The Cell Adhesion Molecule “CAR” and Sialic Acid on Human Erythrocytes Influence Adenovirus In Vivo Biodistribution
Q27641231The Crystal Structure of C2a, the Catalytic Fragment of Classical Pathway C3 and C5 Convertase of Human Complement
Q27643895The Crystal Structure of E. coli rRNA Pseudouridine Synthase RluE
Q27675057The Crystal Structure of a Munc13 C-terminal Module Exhibits a Remarkable Similarity to Vesicle Tethering Factors
Q55920035The Crystal Structure of rna1p
Q27651042The Crystal Structure of the Heparin-Binding Reelin-N Domain of F-Spondin
Q27734689The DNA-binding domain of OmpR: crystal structures of a winged helix transcription factor
Q27642462The DNA-binding domain of human papillomavirus type 18 E1. Crystal structure, dimerization, and DNA binding
Q27667736The DNA-recognition fold of Sso7c4 suggests a new member of SpoVT-AbrB superfamily from archaea
Q39687223The Drosophila transcription factor tramtrack (TTK) interacts with Trithorax-like (GAGA) and represses GAGA-mediated activation
Q57204281The Gene for a Novel Member of the Whey Acidic Protein Family Encodes Three Four-disulfide Core Domains and Is Asynchronously Expressed during Lactation
Q30193221The Grb2 adaptor
Q27640522The H-NS dimerization domain defines a new fold contributing to DNA recognition
Q57975733The Interactions of Cyanobacterial Cytochromec6and Cytochromef, Characterized by NMR
Q27657845The Mannitol Operon Repressor MtlR Belongs to a New Class of Transcription Regulators in Bacteria
Q27652824The Molecular Basis of N-End Rule Recognition
Q46427537The N-acetyl-D-glucosaminylphosphatidylinositol De-N-acetylase of glycosylphosphatidylinositol biosynthesis is a zinc metalloenzyme.
Q44915300The N-terminal carbohydrate recognition site of the cation-independent mannose 6-phosphate receptor
Q24313313The NF-YB/NF-YC structure gives insight into DNA binding and transcription regulation by CCAAT factor NF-Y
Q28755202The NMR solution structure of the 30S ribosomal protein S27e encoded in gene RS27_ARCFU of Archaeoglobus fulgidis reveals a novel protein fold
Q43207551The Noc proteins involved in ribosome synthesis and export contain divergent HEAT repeats.
Q27642246The PB1 domain and the PC motif-containing region are structurally similar protein binding modules
Q33763339The PH superfold: a structural scaffold for multiple functions
Q27637719The PWWP domain of mammalian DNA methyltransferase Dnmt3b defines a new family of DNA-binding folds
Q24298249The PX-BAR membrane-remodeling unit of sorting nexin 9
Q27641587The Purine Repressor of Bacillus subtilis: a Novel Combination of Domains Adapted for Transcription Regulation
Q42674594The Qo site of cytochrome b6f complexes controls the activation of the LHCII kinase
Q24304626The RAC binding domain/IRSp53-MIM homology domain of IRSp53 induces RAC-dependent membrane deformation
Q27934943The RNA-binding SAM domain of Smaug defines a new family of post-transcriptional regulators
Q24522806The RafC1 cysteine-rich domain contains multiple distinct regulatory epitopes which control Ras-dependent Raf activation
Q27640357The Refined Crystal Structure of an Eel Pout Type III Antifreeze Protein RD1 at 0.62-Å Resolution Reveals Structural Microheterogeneity of Protein and Solvation
Q49061448The Sclerotinia sclerotiorum agglutinin represents a novel family of fungal lectins remotely related to the Clostridium botulinum non-toxin haemagglutinin HA33/A.
Q27933622The Shwachman-Bodian-Diamond syndrome protein family is involved in RNA metabolism
Q27641596The Solution Structure of YbcJ from Escherichia coli Reveals a Recently Discovered L Motif Involved in RNA Binding
Q27646578The Structural Basis for the Prevention of Nonsteroidal Antiinflammatory Drug-Induced Gastrointestinal Tract Damage by the C-Lobe of Bovine Colostrum Lactoferrin
Q27650401The Structure of Sucrose Phosphate Synthase from Halothermothrix orenii Reveals Its Mechanism of Action and Binding Mode
Q52175870The TRANSPARENT TESTA GLABRA1 locus, which regulates trichome differentiation and anthocyanin biosynthesis in Arabidopsis, encodes a WD40 repeat protein.
Q57665576The Tetrameric Protein Transthyretin Dissociates to a Non-native Monomer in Solution
Q24793514The Thermal Stability of theFusarium solani pisiCutinase as a Function of pH
Q27639245The Three-dimensional structure of a superantigen-like protein, SET3, from a pathogenicity island of the Staphylococcus aureus genome
Q27934901The Tim21 binding domain connects the preprotein translocases of both mitochondrial membranes
Q27734343The UmuD' protein filament and its potential role in damage induced mutagenesis
Q27640869The X-ray Crystal Structures of Two Constitutively Active Mutants of the Escherichia coli PhoB Receiver Domain Give Insights into Activation
Q27636514The X-ray crystal structure and putative ligand-derived peptide binding properties of gamma-aminobutyric acid receptor type A receptor-associated protein
Q27620444The X-ray crystal structure of beta-ketoacyl [acyl carrier protein] synthase I
Q27625463The X-ray crystal structure of neuronal Sec1 from squid sheds new light on the role of this protein in exocytosis
Q27733169The X-ray crystal structures of Yersinia tyrosine phosphatase with bound tungstate and nitrate. Mechanistic implications
Q27639115The X-ray crystallographic structure of the angiogenesis inhibitor angiostatin
Q27622424The X-ray structure of Brassica napus beta-keto acyl carrier protein reductase and its implications for substrate binding and catalysis
Q27764579The X-ray structure of a cobalamin biosynthetic enzyme, cobalt-precorrin-4 methyltransferase
Q27626265The X-ray structure of the NAD-dependent 5,10-methylenetetrahydrofolate dehydrogenase fromSaccharomyces cerevisiae
Q37480430The X-ray structure of the papillomavirus helicase in complex with its molecular matchmaker E2.
Q28302966The aconitase family: three structural variations on a common theme
Q33886439The activation domain of the MotA transcription factor from bacteriophage T4.
Q42847735The active site and substrates binding mode of malonyl-CoA synthetase determined by transferred nuclear Overhauser effect spectroscopy, site-directed mutagenesis, and comparative modeling studies
Q42637673The active site of drosomycin, a small insect antifungal protein, delineated by comparison with the modeled structure of Rs-AFP2, a plant antifungal protein
Q27618752The allosteric transition of glucosamine-6-phosphate deaminase: the structure of the T state at 2.3 A resolution
Q28274698The antigenic structure of the HIV gp120 envelope glycoprotein
Q35041188The application of computational methods to explore the diversity and structure of bacterial fatty acid synthase
Q77537577The association between a negatively charged ligand and the electronegative binding pocket of its receptor
Q35226259The asymmetry in the mature amino-terminus of ClpP facilitates a local symmetry match in ClpAP and ClpXP complexes
Q27861113The atomic structure of protein-protein recognition sites
Q27619880The atomic-resolution structure of human caspase-8, a key activator of apoptosis
Q27625171The bacterial cell-division protein ZipA and its interaction with an FtsZ fragment revealed by X-ray crystallography
Q47220721The binding of C10 oligomers to Escherichia coli transcription termination factor Rho.
Q27619230The binding of inosine monophosphate to Escherichia coli carbamoyl phosphate synthetase
Q30499501The calcium binding loops of the cytosolic phospholipase A2 C2 domain specify targeting to Golgi and ER in live cells
Q27939658The carboxy terminal WD domain of the pre-mRNA splicing factor Prp17p is critical for function
Q37491609The carboxy-terminal portion of TnsC activates the Tn7 transposase through a specific interaction with TnsA.
Q33863454The carboxyl-terminal region of cyclic nucleotide-modulated channels is a gating ring, not a permeation path
Q38326710The catalytic mechanism of a pyrimidine dimer-specific glycosylase (pdg)/abasic lyase, Chlorella virus-pdg
Q43106688The central kink region of fowlicidin-2, an alpha-helical host defense peptide, is critically involved in bacterial killing and endotoxin neutralization.
Q24646284The central portion of factor H (modules 10-15) is compact and contains a structurally deviant CCP module
Q40224474The coupling of electron transfer and proton translocation: electrostatic calculations on Paracoccus denitrificans cytochrome c oxidase
Q27639726The cross-reactive calcium-binding pollen allergen, Phl p 7, reveals a novel dimer assembly
Q27622443The crystal structure and active site location of isocitrate lyase from the fungus Aspergillus nidulans
Q27637917The crystal structure and mutational analysis of a novel RNA-binding domain found in the human Tap nuclear mRNA export factor
Q34585464The crystal structure and mutational binding analysis of the extracellular domain of the platelet-activating receptor CLEC-2.
Q27641609The crystal structure and reaction mechanism of Escherichia coli 2,4-dienoyl-CoA reductase
Q27640260The crystal structure at 2A resolution of the Ca2+ -binding protein S100P
Q27625372The crystal structure of ADP-L-glycero-D-mannoheptose 6-epimerase: catalysis with a twist
Q24301771The crystal structure of CCG1/TAF(II)250-interacting factor B (CIB)
Q24673432The crystal structure of D-lactate dehydrogenase, a peripheral membrane respiratory enzyme
Q27641418The crystal structure of DJ-1, a protein related to male fertility and Parkinson's disease
Q27627644The crystal structure of DNA mismatch repair protein MutS binding to a G x T mismatch
Q27749085The crystal structure of Dps, a ferritin homolog that binds and protects DNA
Q27647730The crystal structure of Ebp1 reveals a methionine aminopeptidase fold as binding platform for multiple interactions
Q34335181The crystal structure of Escherichia coli MoaB suggests a probable role in molybdenum cofactor synthesis
Q27670846The crystal structure of GXGD membrane protease FlaK
Q24322710The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling
Q27639945The crystal structure of MT0146/CbiT suggests that the putative precorrin-8w decarboxylase is a methyltransferase
Q27638528The crystal structure of Mycobacterium tuberculosis alkylhydroperoxidase AhpD, a potential target for antitubercular drug design
Q27642849The crystal structure of Pseudomonas avirulence protein AvrPphB: A papain-like fold with a distinct substrate-binding site
Q27748921The crystal structure of Pyrococcus furiosus ornithine carbamoyltransferase reveals a key role for oligomerization in enzyme stability at extremely high temperatures
Q28487146The crystal structure of Rv1347c, a putative antibiotic resistance protein from Mycobacterium tuberculosis, reveals a GCN5-related fold and suggests an alternative function in siderophore biosynthesis
Q27620851The crystal structure of a GroEL/peptide complex: plasticity as a basis for substrate diversity
Q27640526The crystal structure of a TL/CD8alphaalpha complex at 2.1 A resolution: implications for modulation of T cell activation and memory
Q27641314The crystal structure of a cockroach pheromone-binding protein suggests a new ligand binding and release mechanism
Q27631567The crystal structure of a heptameric archaeal Sm protein: Implications for the eukaryotic snRNP core
Q27620848The crystal structure of a laminin G-like module reveals the molecular basis of alpha-dystroglycan binding to laminins, perlecan, and agrin
Q27733333The crystal structure of a llama heavy chain variable domain
Q27734729The crystal structure of a major allergen from plants
Q27639112The crystal structure of a major dust mite allergen Der p 2, and its biological implications
Q24683286The crystal structure of a multifunctional protein: phosphoglucose isomerase/autocrine motility factor/neuroleukin
Q27617940The crystal structure of a novel bacterial adenylyltransferase reveals half of sites reactivity
Q27640491The crystal structure of a plant lectin in complex with the Tn antigen
Q27734762The crystal structure of a triacylglycerol lipase from Pseudomonas cepacia reveals a highly open conformation in the absence of a bound inhibitor
Q27640631The crystal structure of a truncated ErbB2 ectodomain reveals an active conformation, poised to interact with other ErbB receptors
Q27640684The crystal structure of aminoglycoside-3'-phosphotransferase-IIa, an enzyme responsible for antibiotic resistance
Q36476885The crystal structure of an eukaryotic iron superoxide dismutase suggests intersubunit cooperation during catalysis
Q30163847The crystal structure of an oxidatively stable subtilisin-like alkaline serine protease, KP-43, with a C-terminal beta-barrel domain
Q27745795The crystal structure of bovine bile salt activated lipase: insights into the bile salt activation mechanism
Q27733274The crystal structure of chloroperoxidase: a heme peroxidase--cytochrome P450 functional hybrid
Q27641398The crystal structure of choline kinase reveals a eukaryotic protein kinase fold
Q27621055The crystal structure of coxsackievirus A9: new insights into the uncoating mechanisms of enteroviruses
Q27748779The crystal structure of dimeric kinesin and implications for microtubule-dependent motility
Q27640960The crystal structure of dipeptidyl peptidase IV (CD26) reveals its functional regulation and enzymatic mechanism
Q27638896The crystal structure of exonuclease RecJ bound to Mn2+ ion suggests how its characteristic motifs are involved in exonuclease activity
Q27765093The crystal structure of flap endonuclease-1 from Methanococcus jannaschii
Q27642398The crystal structure of gankyrin, an oncoprotein found in complexes with cyclin-dependent kinase 4, a 19 S proteasomal ATPase regulator, and the tumor suppressors Rb and p53
Q27639376The crystal structure of human CD21: Implications for Epstein-Barr virus and C3d binding
Q35029280The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response
Q24337291The crystal structure of human adenylate kinase 6: An adenylate kinase localized to the cell nucleus
Q27621393The crystal structure of human eukaryotic release factor eRF1--mechanism of stop codon recognition and peptidyl-tRNA hydrolysis
Q27637732The crystal structure of human tyrosyl-DNA phosphodiesterase, Tdp1
Q27636765The crystal structure of indoleglycerol-phosphate synthase from Thermotoga maritima. Kinetic stabilization by salt bridges
Q34334691The crystal structure of microtubule-associated protein light chain 3, a mammalian homologue of Saccharomyces cerevisiae Atg8.
Q27622320The crystal structure of palmitoyl protein thioesterase 1 and the molecular basis of infantile neuronal ceroid lipofuscinosis
Q27641788The crystal structure of polygalacturonase-inhibiting protein (PGIP), a leucine-rich repeat protein involved in plant defense
Q27637740The crystal structure of rat liver AKR7A1. A dimeric member of the aldo-keto reductase superfamily
Q37534428The crystal structure of ribosomal chaperone trigger factor from Vibrio cholerae
Q27733357The crystal structure of ribosomal protein L14 reveals an important organizational component of the translational apparatus
Q27766382The crystal structure of ribosomal protein L22 from Thermus thermophilus: insights into the mechanism of erythromycin resistance
Q24533285The crystal structure of ribosomal protein S4 reveals a two-domain molecule with an extensive RNA-binding surface: one domain shows structural homology to the ETS DNA-binding motif
Q27632675The crystal structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue suggests cross-linking between ganglioside receptors and the toxin
Q27639497The crystal structure of the AAA domain of the ATP-dependent protease FtsH of Escherichia coli at 1.5 A resolution
Q27642580The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes
Q43251872The crystal structure of the BAR domain from human Bin1/amphiphysin II and its implications for molecular recognition
Q27642364The crystal structure of the Calystegia sepium agglutinin reveals a novel quaternary arrangement of lectin subunits with a beta-prism fold
Q27618615The crystal structure of the DNase domain of colicin E7 in complex with its inhibitor Im7 protein
Q27639923The crystal structure of the Epstein-Barr virus protease shows rearrangement of the processed C terminus
Q27641638The crystal structure of the Escherichia coli YfdW gene product reveals a new fold of two interlaced rings identifying a wide family of CoA transferases
Q27622174The crystal structure of the Fab fragment of a rat monoclonal antibody against the main immunogenic region of the human muscle acetylcholine receptor
Q27765337The crystal structure of the Leishmania major surface proteinase leishmanolysin (gp63)
Q24658416The crystal structure of the N-terminal region of BUB1 provides insight into the mechanism of BUB1 recruitment to kinetochores
Q24291846The crystal structure of the PX domain from p40(phox) bound to phosphatidylinositol 3-phosphate
Q27732232The crystal structure of the antifungal protein zeamatin, a member of the thaumatin-like, PR-5 protein family
Q27742747The crystal structure of the asymmetric GroEL-GroES-(ADP)7 chaperonin complex
Q24314421The crystal structure of the beta-catenin/ICAT complex reveals the inhibitory mechanism of ICAT
Q27732580The crystal structure of the catalytic domain of human urokinase-type plasminogen activator
Q27622258The crystal structure of the chemokine domain of fractalkine shows a novel quaternary arrangement
Q27627511The crystal structure of the fab fragment of the monoclonal antibody MAK33. Implications for folding and interaction with the chaperone bip
Q27734756The crystal structure of the flavin containing enzyme dihydroorotate dehydrogenase A from Lactococcus lactis
Q27621337The crystal structure of the formiminotransferase domain of formiminotransferase-cyclodeaminase: implications for substrate channeling in a bifunctional enzyme
Q24320322The crystal structure of the globular head of complement protein C1q provides a basis for its versatile recognition properties
Q42631836The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites
Q27641648The crystal structure of the major cat allergen Fel d 1, a member of the secretoglobin family
Q30176490The crystal structure of the mouse glandular kallikrein-13 (prorenin converting enzyme).
Q27641697The crystal structure of the novel calcium-binding protein AtCBL2 from Arabidopsis thaliana
Q27639985The crystal structure of the nuclease domain of colicin E7 suggests a mechanism for binding to double-stranded DNA by the H-N-H endonucleases
Q27639138The crystal structure of the olfactory marker protein at 2.3 A resolution
Q30160330The crystal structure of the outer membrane protein VceC from the bacterial pathogen Vibrio cholerae at 1.8 A resolution.
Q27627141The crystal structure of the peptide-binding fragment from the yeast Hsp40 protein Sis1
Q27649739The crystal structure of the periplasmic domain of the Escherichia coli membrane protein insertase YidC contains a substrate binding cleft
Q27639533The crystal structure of the quorum sensing protein TraR bound to its autoinducer and target DNA
Q27637552The crystal structure of the zymogen catalytic domain of complement protease C1r reveals that a disruptive mechanical stress is required to trigger activation of the C1 complex
Q24685438The crystal structures of chloramphenicol phosphotransferase reveal a novel inactivation mechanism
Q27642658The crystal structures of the ferric and ferrous forms of the heme complex of HmuO, a heme oxygenase of Corynebacterium diphtheriae
Q27674965The crystallographic structure of Panicum Mosaic Virus (PMV)
Q27733189The crystallographic structure of phytohemagglutinin-L
Q40487553The discovery of Antarctic RNA viruses: a new game changer
Q37117825The discovery of a novel inhibitor of apoptotic protease activating factor-1 (Apaf-1) for ischemic heart: synthesis, activity and target identification
Q27639655The disulfide bond isomerase DsbC is activated by an immunoglobulin-fold thiol oxidoreductase: crystal structure of the DsbC-DsbDalpha complex
Q38361443The domain-swapped dimer of cyanovirin-N contains two sets of oligosaccharide binding sites in solution
Q27621444The eIF1A solution structure reveals a large RNA-binding surface important for scanning function
Q45087562The effect of physical organic properties on hydrophobic fields
Q53650084The efficiency and specificity of apurinic/apyrimidinic site bypass by human DNA polymerase eta and Sulfolobus solfataricus Dpo4.
Q31034869The electron transfer complex between cytochrome c552 and the CuA domain of the Thermus thermophilus ba3 oxidase. A combined NMR and computational approach
Q41080235The elongation phase of protein synthesis
Q24296497The emerging structural understanding of transglutaminase 3
Q30477979The essential GTPase YphC displays a major domain rearrangement associated with nucleotide binding
Q73731673The essential role of Glu-185 and Tyr-354 residues in the ferroxidase activity of Saccharomyces cerevisiae Fet3
Q24536067The extracellular region of ErbB4 adopts a tethered conformation in the absence of ligand
Q27640321The first crystal structure of archaeal aldolase. Unique tetrameric structure of 2-deoxy-d-ribose-5-phosphate aldolase from the hyperthermophilic archaea Aeropyrum pernix
Q34944353The first three domains of the insulin receptor differ structurally from the insulin-like growth factor 1 receptor in the regions governing ligand specificity
Q53653976The frameshift infidelity of human DNA polymerase lambda. Implications for function.
Q36642736The functional duality of iron regulatory protein 1.
Q73704102The functional role of basic patch, a structural element of Escherichia coli transcript cleavage factors GreA and GreB
Q24317633The genetic and functional basis of isolated 17,20-lyase deficiency
Q39585460The heterodimeric ecdysteroid receptor complex in the brown shrimp Crangon crangon: EcR and RXR isoform characteristics and sensitivity towards the marine pollutant tributyltin
Q44326923The high resolution crystal structure of rat liver AKR7A1: understanding the substrate specificites of the AKR7 family.
Q48018656The histone tails of the nucleosome
Q40763191The identification of a common pathogen-specific HLA class I A*0201-restricted cytotoxic T cell epitope encoded within the heat shock protein 65.
Q27642531The intracellular chloride ion channel protein CLIC1 undergoes a redox-controlled structural transition
Q40149993The lifetime of insulin hexamers
Q44062013The liverwort contains a lectin that is structurally and evolutionary related to the monocot mannose-binding lectins.
Q27635501The location of the ligand-binding site of carbohydrate-binding modules that have evolved from a common sequence is not conserved
Q34341843The mannose-dependent epitope for neutralizing antibody 2G12 on human immunodeficiency virus type 1 glycoprotein gp120.
Q42155548The measured and calculated affinity of methyl- and methoxy-substituted benzoquinones for the Q(A) site of bacterial reaction centers
Q27628802The mechanism of substrate (aglycone) specificity in beta -glucosidases is revealed by crystal structures of mutant maize beta -glucosidase-DIMBOA, -DIMBOAGlc, and -dhurrin complexes
Q29615234The mechanisms of vesicle budding and fusion
Q44904787The metal-free and calcium-bound structures of a gamma-carboxyglutamic acid-containing contryphan from Conus marmoreus, glacontryphan-M.
Q41713507The modular structure of actin-regulatory proteins
Q27642308The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domain
Q52652201The molecular basis of the differential subcellular localization of FYVE domains.
Q36426545The molecular structure of Rv1873, a conserved hypothetical protein from Mycobacterium tuberculosis, at 1.38 A resolution
Q33911664The molecular structure of the Toll-like receptor 3 ligand-binding domain.
Q27730709The molecular structure of the complex of Ascaris chymotrypsin/elastase inhibitor with porcine elastase
Q34448263The murine orthologue of human antichymotrypsin: a structural paradigm for clade A3 serpins
Q27643137The nsp9 replicase protein of SARS-coronavirus, structure and functional insights
Q34006354The nucleotide excision repair protein UvrB, a helicase-like enzyme with a catch.
Q27734763The open conformation of a Pseudomonas lipase
Q42677283The open pore conformation of potassium channels
Q30361144The open state of human topoisomerase I as probed by molecular dynamics simulation
Q42649818The orientations of cytochrome c in the highly dynamic complex with cytochrome b5 visualized by NMR and docking using HADDOCK.
Q40389337The origin of C1A-C2 interdomain interactions in protein kinase Calpha.
Q30159954The outer membrane protein OmpW forms an eight-stranded beta-barrel with a hydrophobic channel
Q24542010The phi29 DNA polymerase:protein-primer structure suggests a model for the initiation to elongation transition
Q30159822The phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains.
Q30423126The picornaviral 3C proteinases: cysteine nucleophiles in serine proteinase folds
Q27627230The polar T1 interface is linked to conformational changes that open the voltage-gated potassium channel
Q58428667The polygalacturonase-inhibiting protein PGIP2 of Phaseolus vulgaris has evolved a mixed mode of inhibition of endopolygalacturonase PG1 of Botrytis cinerea
Q36791306The positions of TFIIF and TFIIE in the RNA polymerase II transcription preinitiation complex.
Q27740048The primary fibrin polymerization pocket: three-dimensional structure of a 30-kDa C-terminal gamma chain fragment complexed with the peptide Gly-Pro-Arg-Pro
Q27733966The prosequence of procaricain forms an alpha-helical domain that prevents access to the substrate-binding cleft
Q45269782The putidaredoxin reductase-putidaredoxin electron transfer complex: theoretical and experimental studies
Q27640645The receptor binding protein P2 of PRD1, a virus targeting antibiotic-resistant bacteria, has a novel fold suggesting multiple functions
Q34437425The receptor binding site of human interleukin-3 defined by mutagenesis and molecular modeling
Q27734773The refined crystal structure of the 3C gene product from hepatitis A virus: specific proteinase activity and RNA recognition
Q27738361The repeating segments of the F-actin cross-linking gelation factor (ABP-120) have an immunoglobulin-like fold
Q27621776The retro-GCN4 leucine zipper sequence forms a stable three-dimensional structure
Q27638080The rhesus rotavirus VP4 sialic acid binding domain has a galectin fold with a novel carbohydrate binding site
Q40744383The role of an exposed loop in the alpha2 domain in the mouse MHC class I H-2Dd molecule for recognition by the monoclonal antibody 34-5-8S and the NK-cell receptor Ly49A.
Q47983320The role of electrostatic interactions for cytochrome c oxidase function
Q43738133The role of electrostatic interactions in the regulation of the membrane association of G protein beta gamma heterodimers
Q35146229The role of electrostatics in proton-conducting membrane protein complexes
Q42846482The role of polar interactions in the molecular recognition of CD40L with its receptor CD40
Q41783489The role of position a in determining the stability and oligomerization state of alpha-helical coiled coils: 20 amino acid stability coefficients in the hydrophobic core of proteins
Q34394110The role of the TolC family in protein transport and multidrug efflux. From stereochemical certainty to mechanistic hypothesis
Q27733399The role of the divalent cation in the structure of the I domain from the CD11a/CD18 integrin
Q44564172The roles of the two zinc binding sites in DnaJ.
Q27766354The rub family of ubiquitin-like proteins. Crystal structure of Arabidopsis rub1 and expression of multiple rubs in Arabidopsis
Q37094749The severe acute respiratory syndrome-coronavirus replicative protein nsp9 is a single-stranded RNA-binding subunit unique in the RNA virus world.
Q27617965The signal transducer gp130: Solution structure of the carboxy-terminal domain of the cytokine receptor homology region
Q35809645The simulation approach to bacterial outer membrane proteins.
Q34324028The sliding filament model: 1972-2004.
Q44384610The snake venom protein botrocetin acts as a biological brace to promote dysfunctional platelet aggregation
Q27748825The solution structure and dynamics of the pleckstrin homology domain of G protein-coupled receptor kinase 2 (beta-adrenergic receptor kinase 1). A binding partner of Gbetagamma subunits
Q27618375The solution structure of FADD death domain. Structural basis of death domain interactions of Fas and FADD
Q28647550The solution structure of HIV-1 Nef reveals an unexpected fold and permits delineation of the binding surface for the SH3 domain of Hck tyrosine protein kinase
Q35110861The solution structure of REF2-I reveals interdomain interactions and regions involved in binding mRNA export factors and RNA.
Q27620039The solution structure of VAT-N reveals a 'missing link' in the evolution of complex enzymes from a simple betaalphabetabeta element
Q27734816The solution structure of a specific GAGA factor-DNA complex reveals a modular binding mode
Q27741511The solution structure of an HMG-I(Y)-DNA complex defines a new architectural minor groove binding motif
Q27641885The solution structure of bovine pancreatic trypsin inhibitor at high pressure
Q27639413The solution structure of human hepcidin, a peptide hormone with antimicrobial activity that is involved in iron uptake and hereditary hemochromatosis
Q27733262The solution structure of human thioredoxin complexed with its target from Ref-1 reveals peptide chain reversal
Q33889241The solution structure of ribosomal protein S4 delta41 reveals two subdomains and a positively charged surface that may interact with RNA
Q27732551The solution structure of the Mu Ner protein reveals a helix-turn-helix DNA recognition motif
Q27748909The solution structure of the N-terminal domain of hepatocyte growth factor reveals a potential heparin-binding site
Q27639251The solution structure of the bacteriophage lambda head-tail joining protein, gpFII
Q41075060The solution structure of the bovine leukaemia virus matrix protein and similarity with lentiviral matrix proteins.
Q27639827The structural and functional analysis of the hemoglobin D component from chicken
Q29547190The structural basis for 14-3-3:phosphopeptide binding specificity
Q28248816The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3
Q27619945The structural basis for the recognition of diverse receptor sequences by TRAF2
Q22011010The structural basis of Rho effector recognition revealed by the crystal structure of human RhoA complexed with the effector domain of PKN/PRK1
Q33941852The structural basis of damaged DNA recognition and endonucleolytic cleavage for very short patch repair endonuclease
Q27766417The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen
Q33932430The structural basis of muscle contraction
Q24321332The structural basis of novel endosome anchoring activity of KIF16B kinesin
Q27624954The structural basis of repertoire shift in an immune response to phosphocholine
Q24320225The structural basis of the activation of Ras by Sos
Q27637126The structural mechanism of GTP stabilized oligomerization and catalytic activation of the Toxoplasma gondii uracil phosphoribosyltransferase
Q24301380The structure and biochemical properties of the human spliceosomal protein U1C
Q27640359The structure and function of MCM from archaeal M. Thermoautotrophicum
Q38328829The structure and function of a foot-and-mouth disease virus-oligosaccharide receptor complex.
Q24599597The structure and function of the beta 2-adaptin appendage domain
Q27622617The structure and the characteristic DNA binding property of the C-terminal domain of the RNA polymerase alpha subunit from Thermus thermophilus
Q27641435The structure of Aip1p, a WD repeat protein that regulates Cofilin-mediated actin depolymerization
Q27655708The structure of Aquifex aeolicus sulfide:quinone oxidoreductase, a basis to understand sulfide detoxification and respiration
Q27653923The structure of C2b, a fragment of complement component C2 produced during C3 convertase formation
Q27732750The structure of Desulfovibrio vulgaris rubrerythrin reveals a unique combination of rubredoxin-like FeS4 and ferritin-like diiron domains
Q27620459The structure of Escherichia coli DNA topoisomerase III
Q40573344The structure of GFRalpha1 domain 3 reveals new insights into GDNF binding and RET activation
Q41971165The structure of HIV-1 reverse transcriptase complexed with an RNA pseudoknot inhibitor
Q27739151The structure of I-Crel, a group I intron-encoded homing endonuclease
Q27698536The structure of PccH from Geobacter sulfurreducens - a novel low reduction potential monoheme cytochrome essential for accepting electrons from an electrode
Q27758801The structure of PurR mutant L54M shows an alternative route to DNA kinking
Q45133841The structure of RalF, an ADP-ribosylation factor guanine nucleotide exchange factor from Legionella pneumophila, reveals the presence of a cap over the active site
Q27639324The structure of Rhodothermus marinus Cel12A, a highly thermostable family 12 endoglucanase, at 1.8 A resolution
Q24536308The structure of Saccharomyces cerevisiae Met8p, a bifunctional dehydrogenase and ferrochelatase
Q27765104The structure of VanX reveals a novel amino-dipeptidase involved in mediating transposon-based vancomycin resistance
Q27626640The structure of a CREB bZIP.somatostatin CRE complex reveals the basis for selective dimerization and divalent cation-enhanced DNA binding
Q27638168The structure of a binary complex between a mammalian mevalonate kinase and ATP: insights into the reaction mechanism and human inherited disease
Q27640147The structure of a cold-adapted family 8 xylanase at 1.3 A resolution. Structural adaptations to cold and investgation of the active site
Q27618619The structure of active serpin 1K from Manduca sexta
Q27639817The structure of an FF domain from human HYPA/FBP11
Q27627420The structure of an HIV-1 specific cell entry inhibitor in complex with the HIV-1 gp41 trimeric core
Q27665628The structure of an Iws1/Spt6 complex reveals an interaction domain conserved in TFIIS, Elongin A and Med26
Q24303524The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3
Q27639653The structure of bacterial DnaA: implications for general mechanisms underlying DNA replication initiation
Q27641798The structure of barley alpha-amylase isozyme 1 reveals a novel role of domain C in substrate recognition and binding: a pair of sugar tongs
Q27619175The structure of bovine glutamate dehydrogenase provides insights into the mechanism of allostery
Q42110043The structure of bovine mitochondrial adenylate kinase: comparison with isoenzymes in other compartments
Q28262767The structure of chondroitin B lyase complexed with glycosaminoglycan oligosaccharides unravels a calcium-dependent catalytic machinery
Q70976276The structure of coxsackievirus B3 at 3.5 A resolution
Q27733258The structure of elongation factor G in complex with GDP: conformational flexibility and nucleotide exchange
Q27647581The structure of human 4F2hc ectodomain provides a model for homodimerization and electrostatic interaction with plasma membrane
Q27760354The structure of immunoglobulin superfamily domains 1 and 2 of MAdCAM-1 reveals novel features important for integrin recognition
Q27733820The structure of lactate dehydrogenase from Plasmodium falciparum reveals a new target for anti-malarial design
Q27748747The structure of mammalian 15-lipoxygenase reveals similarity to the lipases and the determinants of substrate specificity
Q24630729The structure of mouse HP1 suggests a unique mode of single peptide recognition by the shadow chromo domain dimer
Q34298519The structure of nucleosome assembly protein 1.
Q27636657The structure of phosphorylated GSK-3beta complexed with a peptide, FRATtide, that inhibits beta-catenin phosphorylation
Q27745763The structure of ribosomal protein S7 at 1.9 A resolution reveals a beta-hairpin motif that binds double-stranded nucleic acids
Q27729456The structure of satellite panicum mosaic virus at 1.9 A resolution
Q27733368The structure of simian virus 40 refined at 3.1 A resolution
Q57801224The structure of the 2[4Fe–4S] ferredoxin from Pseudomonas aeruginosa at 1.32-Å resolution: comparison with other high-resolution structures of ferredoxins and contributing structural features to reduction potential values
Q27640695The structure of the GGA1-GAT domain reveals the molecular basis for ARF binding and membrane association of GGAs
Q27647289The structure of the Haemophilus influenzae HMW1 pro-piece reveals a structural domain essential for bacterial two-partner secretion
Q27658634The structure of the KlcA and ArdB proteins reveals a novel fold and antirestriction activity against Type I DNA restriction systems in vivo but not in vitro
Q27644784The structure of the Met144Leu mutant of copper nitrite reductase from Alcaligenes xylosoxidans provides the first glimpse of a protein-protein complex with azurin II
Q27622446The structure of the N-terminal actin-binding domain of human dystrophin and how mutations in this domain may cause Duchenne or Becker muscular dystrophy
Q27639767The structure of the RlmB 23S rRNA methyltransferase reveals a new methyltransferase fold with a unique knot
Q34360440The structure of the TRAPP subunit TPC6 suggests a model for a TRAPP subcomplex
Q40919866The structure of the TrmE GTP-binding protein and its implications for tRNA modification
Q24681613The structure of the cell cycle protein Cdc14 reveals a proline-directed protein phosphatase
Q43205663The structure of the flock house virus B2 protein, a viral suppressor of RNA interference, shows a novel mode of double-stranded RNA recognition
Q27627787The structure of the mRNA export factor TAP reveals a cis arrangement of a non-canonical RNP domain and an LRR domain
Q27638997The structure of the mammalian 20S proteasome at 2.75 A resolution
Q22001450The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs
Q27641750The structure of the receptor-binding domain of the bacteriophage T4 short tail fibre reveals a knitted trimeric metal-binding fold
Q27621062The structure of the signal receiver domain of the Arabidopsis thaliana ethylene receptor ETR1
Q27639137The structure of the soluble domain of an archaeal Rieske iron-sulfur protein at 1.1 A resolution
Q27748973The structure of tobacco ringspot virus: a link in the evolution of icosahedral capsids in the picornavirus superfamily
Q27639889The structure of tomato aspermy virus by X-ray crystallography
Q27641881The structure ofPseudomonasP51 Cl-muconate lactonizing enzyme: Co-evolution of structure and dynamics with the dehalogenation function
Q27625099The structures of caspases-1, -3, -7 and -8 reveal the basis for substrate and inhibitor selectivity
Q41792150The structures of exocyst subunit Exo70p and the Exo84p C-terminal domains reveal a common motif
Q33958138The structures of the thrombospondin-1 N-terminal domain and its complex with a synthetic pentameric heparin
Q74084308The surface exposed amino acid residues of monomeric proteins determine the partitioning in aqueous two-phase systems
Q41397050The swinging lever-arm hypothesis of muscle contraction.
Q30916971The tetrameric L27 domain complex as an organization platform for supramolecular assemblies
Q27640319The tetrameric structure of Haemophilus influenza hybrid Prx5 reveals interactions between electron donor and acceptor proteins
Q27640134The three-dimensional solution structure of NaD1, a new floral defensin from Nicotiana alata and its application to a homology model of the crop defense protein alfAFP
Q39110969The three-dimensional solution structure of the SRC homology domain-2 of the growth factor receptor-bound protein-2.
Q33887537The three-dimensional solution structure of the matrix protein from the type D retrovirus, the Mason-Pfizer monkey virus, and implications for the morphology of retroviral assembly
Q27619244The three-dimensional structure of Asp189Ser trypsin provides evidence for an inherent structural plasticity of the protease
Q27739430The three-dimensional structure of an H-2Ld-peptide complex explains the unique interaction of Ld with beta-2 microglobulin and peptide
Q27733824The three-dimensional structure of bovine odorant binding protein and its mechanism of odor recognition
Q27619877The three-dimensional structure of caspase-8: an initiator enzyme in apoptosis
Q27621065The three-dimensional structure of the HRDC domain and implications for the Werner and Bloom syndrome proteins
Q27641280The three-dimensional structure of the core domain of Naf Y from Azotobacter vinelandii determined at 1.8-A resolution
Q27642015The three-dimensional structures of two beta-agarases
Q24293033The trihelical bundle subdomain of the GGA proteins interacts with multiple partners through overlapping but distinct sites
Q27633137The trimer-of-hairpins motif in membrane fusion: Visna virus
Q36298878The unusual chaperonins of Mycobacterium tuberculosis
Q36281716The use of nucleotide analogs to evaluate the mechanism of the heterotropic response of Escherichia coli aspartate transcarbamoylase
Q58489224The waters of life
Q28145061The whey acidic protein family: a new signature motif and three-dimensional structure by comparative modeling
Q27729875The x-ray structure of an anti-tumour antibody in complex with antigen
Q40442512The zinc ribbon domains of the general transcription factors TFIIB and Brf: conserved functional surfaces but different roles in transcription initiation.
Q27666286The “Phantom Effect” of the Rexinoid LG100754: Structural and Functional Insights
Q52115212Theoretical calculations of the permeability of monensin-cation complexes in model bio-membranes.
Q35618234Thermodynamic and structural characterization of 2'-nitrogen-modified RNA duplexes.
Q30320622Thermodynamic characterization of the interaction of human cyclophilin 18 with cyclosporin A.
Q44038207Thermodynamic consequences of burial of polar and non-polar amino acid residues in the protein interior
Q45110737Thermodynamic studies on the interaction of the third complement component and its inhibitor, compstatin
Q73728049Thermodynamics of Ras/effector and Cdc42/effector interactions probed by isothermal titration calorimetry
Q47900434Thermodynamics of amino acid side-chain internal rotations
Q43600503Thermostabilization of a chimeric enzyme by residue substitutions: four amino acid residues in loop regions are responsible for the thermostability of Thermus thermophilus isopropylmalate dehydrogenase
Q43977218Thiol-modifying inhibitors for understanding squalene cyclase function
Q52573321Threading analysis of the Pitx2 homeodomain: predicted structural effects of mutations causing Rieger syndrome and iridogoniodysgenesis.
Q34297818Threading analysis suggests that the obese gene product may be a helical cytokine
Q28487100Three different putative phosphate transport receptors are encoded by the Mycobacterium tuberculosis genome and are present at the surface of Mycobacterium bovis BCG
Q52553599Three discrete regions of mammalian adenylyl cyclase form a site for Gsalpha activation.
Q44257223Three-dimensional models of proteases involved in patterning of the Drosophila Embryo. Crucial role of predicted cation binding sites
Q27641122Three-dimensional solution structure of an archaeal FKBP with a dual function of peptidyl prolyl cis-trans isomerase and chaperone-like activities
Q27620957Three-dimensional solution structure of mouse [Cd7]-metallothionein-l by homonuclear and heteronuclear NMR spectroscopy
Q24533287Three-dimensional solution structure of the 44 kDa ectodomain of SIV gp41
Q27639429Three-dimensional solution structure of the sodium channel agonist/antagonist delta-conotoxin TxVIA
Q46912392Three-dimensional structural studies on fragments of fibrinogen and fibrin
Q28115912Three-dimensional structural views of damaged-DNA recognition: T4 endonuclease V, E. coli Vsr protein, and human nucleotide excision repair factor XPA
Q53623694Three-dimensional structure of AzoR from Escherichia coli. An oxidereductase conserved in microorganisms.
Q27618640Three-dimensional structure of a barley beta-D-glucan exohydrolase, a family 3 glycosyl hydrolase
Q27620621Three-dimensional structure of a complex between the death domains of Pelle and Tube
Q33788320Three-dimensional structure of a halotolerant algal carbonic anhydrase predicts halotolerance of a mammalian homolog
Q33650502Three-dimensional structure of herpes simplex virus type 1 glycoprotein D at 2.4-nanometer resolution
Q27638849Three-dimensional structure of human gamma -glutamyl hydrolase. A class I glatamine amidotransferase adapted for a complex substate
Q27640050Three-dimensional structure of manganese superoxide dismutase from Bacillus halodenitrificans, a component of the so-called "green protein"
Q27766849Three-dimensional structure of phosphoenolpyruvate carboxylase: a proposed mechanism for allosteric inhibition
Q27731178Three-dimensional structure of the 67K N-terminal fragment of E. coli DNA topoisomerase I
Q28115243Three-dimensional structure of the bifunctional protein PCD/DCoH, a cytoplasmic enzyme interacting with transcription factor HNF1
Q27729832Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1
Q27732574Three-dimensional structure of the human 'protective protein': structure of the precursor form suggests a complex activation mechanism
Q27734749Three-dimensional structure of the tyrosine kinase c-Src
Q27625349Three-dimensional structures ofDrosophila melanogasteracetylcholinesterase and of its complexes with two potent inhibitors
Q79169010Thrombin inhibitors with novel P1 binding pocket functionality: free energy of binding analysis
Q24306229Thyroxine-thyroid hormone receptor interactions
Q56877674Time-resolved X-ray crystallography: uncovering reaction intermediates in biochemical processes
Q37330168Topologies of complexes containing O6-alkylguanine-DNA alkyltransferase and DNA.
Q47699978Toward a predictive understanding of molecular recognition
Q27641495Towards an understanding of the poliovirus replication complex: the solution structure of the soluble domain of the poliovirus 3A protein
Q27641239Transcarboxylase 12S crystal structure: hexamer assembly and substrate binding to a multienzyme core
Q37524472Transcarboxylase 5S structures: assembly and catalytic mechanism of a multienzyme complex subunit
Q34141508Transcription factors: global and detailed views
Q39771424Transcription regulation of caspase-1 by R393 of HIPPI and its molecular partner HIP-1.
Q83321525Transcriptional regulation of the agr locus and the identification of DNA binding residues of the global regulatory protein SarR in Staphylococcus aureus
Q53406520Transduction of Activation Signal That Follows HIV-1 Binding to CD4 and CD4 Dimerization Involves the Immunoglobulin CDR3-like Region in Domain 1 of CD4
Q50776259Transient homodimer interactions studied using the electron self-exchange reaction.
Q34509062Translesion DNA Synthesis
Q38293932Translocation portals for the substrates and products of a viral transcription complex: the bluetongue virus core.
Q38270000Transmembrane signal transduction of the alpha(IIb)beta(3) integrin
Q27646459Trehalulose synthase native and carbohydrate complexed structures provide insights into sucrose isomerization
Q27626880Triphosphate structure of guanylate-binding protein 1 and implications for nucleotide binding and GTPase mechanism
Q38315991Trp scanning analysis of Tet repressor reveals conformational changes associated with operator and anhydrotetracycline binding
Q28114825Truncated mutants of human thioredoxin reductase 1 do not exhibit glutathione reductase activity
Q33666869Turn up the HEAT.
Q39714839Turning a disulfide isomerase into an oxidase: DsbC mutants that imitate DsbA.
Q27637264Twists and turns of the cation-dependent mannose 6-phosphate receptor. Ligand-bound versus ligand-free receptor
Q30049026Two Polymorphic Forms of Human Histamine Methyltransferase
Q36278235Two conformational states of Candida rugosa lipase
Q27629340Two different, highly exposed, bulged structures for an unusually long peptide bound to rat MHC class I RT1-Aa
Q27757472Two human T cell receptors bind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids
Q27629371Two mutants of human heparin binding protein (CAP37): toward the understanding of the nature of lipid A/LPS and BPTI binding
Q27639421Two new crystal forms of the choline-binding domain of the major pneumococcal autolysin: insights into the dynamics of the active homodimer
Q27634937Two polymorphic forms of human histamine methyltransferase: structural, thermal, and kinetic comparisons
Q28214520Two short segments of Smad3 are important for specific interaction of Smad3 with c-Ski and SnoN
Q71337295Two structurally different RNA molecules are bound by the spliceosomal protein U1A using the same recognition strategy
Q36642707Two-site substrate recognition model for the Keap1-Nrf2 system: a hinge and latch mechanism
Q27625224Ulp1-SUMO crystal structure and genetic analysis reveal conserved interactions and a regulatory element essential for cell growth in yeast
Q34179802Unbinding of retinoic acid from its receptor studied by steered molecular dynamics
Q44121897Unfolding of a leucine zipper is not a simple two-state transition
Q40570410Unique physicochemical properties of human enteric Ad41 responsible for its survival and replication in the gastrointestinal tract
Q38318740Uniquely altered DNA replication fidelity conferred by an amino acid change in the nucleotide binding pocket of human immunodeficiency virus type 1 reverse transcriptase
Q77393276Unmyristoylated MARCKS-related protein (MRP) binds to supported planar phosphatidylcholine membranes
Q41839982Unraveling viral interleukin-6 binding to gp130 and activation of STAT-signaling pathways independently of the interleukin-6 receptor
Q27635472Unusual binding properties of the SH3 domain of the yeast actin-binding protein Abp1: structural and functional analysis
Q28492693UreG, a chaperone in the urease assembly process, is an intrinsically unstructured GTPase that specifically binds Zn2+
Q73370274Use of combinatorial mutagenesis to select for multiply substituted human interleukin-3 variants with improved pharmacologic properties
Q30336320Using electrostatic potentials to predict DNA-binding sites on DNA-binding proteins.
Q79210002Using multiple structure alignments, fast model building, and energetic analysis in fold recognition and homology modeling
Q30366195VASP-E: specificity annotation with a volumetric analysis of electrostatic isopotentials.
Q33683387VASP: a volumetric analysis of surface properties yields insights into protein-ligand binding specificity
Q33718451VP40 octamers are essential for Ebola virus replication.
Q28343571Variation in aspects of cysteine proteinase catalytic mechanism deduced by spectroscopic observation of dithioester intermediates, kinetic analysis and molecular dynamics simulations
Q27740067Vascular endothelial growth factor: crystal structure and functional mapping of the kinase domain receptor binding site
Q44444036Versatility of selenium catalysis in PHGPx unraveled by LC/ESI-MS/MS.
Q77520952Vertical-scanning mutagenesis of a critical tryptophan in the minor groove binding track of HIV-1 reverse transcriptase. Molecular nature of polymerase-nucleic acid interactions
Q27640250Viability of a drug-resistant human immunodeficiency virus type 1 protease variant: structural insights for better antiviral therapy
Q33869718Virus Particle Explorer (VIPER), a website for virus capsid structures and their computational analyses
Q27648139Virus-Encoded Aminoacyl-tRNA Synthetases: Structural and Functional Characterization of Mimivirus TyrRS and MetRS
Q78010480Visual arrestin activity may be regulated by self-association
Q30678312Water mediation is essential to nucleation of β-turn formation in peptide folding motifs
Q36278901Water molecules participate in proteinase-inhibitor interactions: crystal structures of Leu18, Ala18, and Gly18 variants of turkey ovomucoid inhibitor third domain complexed with Streptomyces griseus proteinase B.
Q42183781Water-mediated protein-DNA interactions: the relationship of thermodynamics to structural detail
Q35214098Water-protein interactions from high-resolution protein crystallography
Q33824236Wet and dry interfaces: the role of solvent in protein-protein and protein-DNA recognition
Q57255941What Happens to Hydrophobic Interactions during Transfer from the Solution to the Gas Phase? The Case of Electrospray-Based Soft Ionization Methods
Q29617630Winged helix proteins
Q27628912X-Ray structures of the universal translation initiation factor IF2/eIF5B: conformational changes on GDP and GTP binding
Q24643534X-linked dominant scapuloperoneal myopathy is due to a mutation in the gene encoding four-and-a-half-LIM protein 1
Q71799416X-ray analysis reveals conformational adaptation of the linker in functional calmodulin mutants
Q27639516X-ray crystal structure and functional analysis of vaccinia virus K3L reveals molecular determinants for PKR subversion and substrate recognition
Q27642339X-ray crystal structure of IRF-3 and its functional implications
Q27636876X-ray crystal structure of MTH938 from Methanobacterium thermoautotrophicum at 2.2 A resolution reveals a novel tertiary protein fold
Q27619882X-ray crystal structure of aminoimidazole ribonucleotide synthetase (PurM), from the Escherichia coli purine biosynthetic pathway at 2.5 A resolution
Q27639741X-ray crystal structure of the C4d fragment of human complement component C4
Q27650146X-ray crystal structure of the polymerase domain of the bacteriophage N4 virion RNA polymerase
Q28264769X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation
Q27627412X-ray crystallographic study of xylopentaose binding to Pseudomonas fluorescens xylanase A
Q27641205X-ray snapshots of the maturation of an antibody response to a protein antigen
Q27632183X-ray structure of 12-oxophytodienoate reductase 1 provides structural insight into substrate binding and specificity within the family of OYE
Q27639349X-ray structure of Saccharomyces cerevisiae homologous mitochondrial matrix factor 1 (Hmf1)
Q27732630X-ray structure of Streptococcus pneumoniae PBP2x, a primary penicillin target enzyme
Q27617519X-ray structure of T4 endonuclease VII: a DNA junction resolvase with a novel fold and unusual domain-swapped dimer architecture
Q27638957X-ray structure of a neuronal complexin-SNARE complex from squid
Q27732532X-ray structure of an anti-fungal chitosanase from streptomyces N174
Q27641926X-ray structure of isoaspartyl dipeptidase from E.coli: a dinuclear zinc peptidase evolved from amidohydrolases
Q27642214X-ray structure of methanol dehydrogenase from Paracoccus denitrificans and molecular modeling of its interactions with cytochrome c-551i
Q27618652X-ray structure of pyrrolidone carboxyl peptidase from the hyperthermophilic archaeon Thermococcus litoralis
Q27634137X-ray structure of sensory rhodopsin II at 2.1-A resolution
Q27652299X-ray structure of the complex of regulatory subunits of human DNA polymerase delta
Q27684675X-ray structure of the first `extremo-α-carbonic anhydrase', a dimeric enzyme from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1
Q24635298X-ray structure of the human hyperplastic discs protein: an ortholog of the C-terminal domain of poly(A)-binding protein
Q27642835X-ray structure of translation initiation factor eIF2gamma: implications for tRNA and eIF2alpha binding
Q27640369X-ray structures of Myc-Max and Mad-Max recognizing DNA. Molecular bases of regulation by proto-oncogenic transcription factors
Q27622688X-ray structures of a novel acid phosphatase from Escherichia blattae and its complex with the transition-state analog molybdate
Q42170534X-ray structures of free and leupeptin-complexed human alphaI-tryptase mutants: indication for an alpha-->beta-tryptase transition
Q27730902X-ray structures of isoforms of the actin-binding protein profilin that differ in their affinity for phosphatidylinositol phosphates
Q24672546XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators
Q63570266Xylanase–oligosaccharide interactions studied by a competitive enzyme assay
Q57412406Yeast Transcript Elongation Factor (TFIIS), Structure and Function
Q27641817YodA from Escherichia coli is a metal-binding, lipocalin-like protein
Q27670870ZF21 Protein, a Regulator of the Disassembly of Focal Adhesions and Cancer Metastasis, Contains a Novel Noncanonical Pleckstrin Homology Domain
Q35647276e-molecular shapes and properties
Q27618735mRNA cap recognition: dominant role of enhanced stacking interactions between methylated bases and protein aromatic side chains
Q28910366p27 binds cyclin-CDK complexes through a sequential mechanism involving binding-induced protein folding
Q42845189pH-Dependent self-association of the Src homology 2 (SH2) domain of the Src homologous and collagen-like (SHC) protein.
Q30546746pH-triggered conformational switching of the diphtheria toxin T-domain: the roles of N-terminal histidines
Q60340673“RKKH” Peptides from the Snake Venom Metalloproteinase ofBothrops jararacaBind Near the Metal Ion-dependent Adhesion Site of the Human Integrin α2I-domain
Q27641805Origin of higher affinity to RNA of the N-terminal RNA-binding domain than that of the C-terminal one of a mouse neural protein, musashi1, as revealed by comparison of their structures, modes of interaction, surface electrostatic potentials, and bac
Q24673986Structure of a complex of the human alpha/beta T cell receptor (TCR) HA1.7, influenza hemagglutinin peptide, and major histocompatibility complex class II molecule, HLA-DR4 (DRA*0101 and DRB1*0401): insight into TCR cross-restriction and alloreactiv

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