scholarly article | Q13442814 |
P50 | author | Joseph Sodroski | Q64524473 |
Peter D. Kwong | Q68690794 | ||
Richard T. Wyatt | Q96247131 | ||
P2093 | author name string | W A Hendrickson | |
J Robinson | |||
R W Sweet | |||
S Majeed | |||
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A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors | Q28118386 | ||
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Oligomeric modeling and electrostatic analysis of the gp120 envelope glycoprotein of human immunodeficiency virus | Q33797989 | ||
The level of CD4 expression limits infection of primary rhesus monkey macrophages by a T-tropic simian immunodeficiency virus and macrophagetropic human immunodeficiency viruses | Q33826504 | ||
Why protein crystals favour some space-groups over others | Q34400973 | ||
Crystal structure of an HIV-binding recombinant fragment of human CD4. | Q34637157 | ||
Replicative function and neutralization sensitivity of envelope glycoproteins from primary and T-cell line-passaged human immunodeficiency virus type 1 isolates. | Q35841780 | ||
Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured human brain tissue: identification of replication-competent and -defective viral genomes | Q36796806 | ||
Three-dimensional structure of poliovirus receptor bound to poliovirus | Q37141992 | ||
Envelope proteins from clinical isolates of human immunodeficiency virus type 1 that are refractory to neutralization by soluble CD4 possess high affinity for the CD4 receptor | Q37588188 | ||
Rapid selection for an N-linked oligosaccharide by monoclonal antibodies directed against the V3 loop of human immunodeficiency virus type 1. | Q38359755 | ||
HIV-1-induced cell fusion is mediated by multiple regions within both the viral envelope and the CCR-5 co-receptor | Q38908745 | ||
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V2 loop glycosylation of the human immunodeficiency virus type 1 SF162 envelope facilitates interaction of this protein with CD4 and CCR5 receptors and protects the virus from neutralization by anti-V3 loop and anti-CD4 binding site antibodies | Q39592261 | ||
Selection for neutralization resistance of the simian/human immunodeficiency virus SHIVSF33A variant in vivo by virtue of sequence changes in the extracellular envelope glycoprotein that modify N-linked glycosylation. | Q39594428 | ||
CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5. | Q39605077 | ||
Regulation of Oxygen Affinity of Hemoglobin: Influence of Structure of the Globin on the Heme Iron | Q39805445 | ||
Neutralization of the human immunodeficiency virus type 1 primary isolate JR-FL by human monoclonal antibodies correlates with antibody binding to the oligomeric form of the envelope glycoprotein complex | Q39878965 | ||
Critical role of enhanced CD4 affinity in laboratory adaptation of human immunodeficiency virus type 1. | Q40870962 | ||
The V1/V2 region of human immunodeficiency virus type 1 modulates the sensitivity to neutralization by soluble CD4 and cellular tropism | Q41085877 | ||
Characterization of envelope and core structural gene products of HTLV-III with sera from AIDS patients | Q41936910 | ||
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Probability analysis of variational crystallization and its application to gp120, the exterior envelope glycoprotein of type 1 human immunodeficiency virus (HIV-1). | Q45751477 | ||
Major glycoprotein antigens that induce antibodies in AIDS patients are encoded by HTLV-III. | Q48378749 | ||
Characterization of gp41 as the transmembrane protein coded by the HTLV-III/LAV envelope gene. | Q55244821 | ||
P433 | issue | 12 | |
P921 | main subject | HIV | Q15787 |
laboratory | Q483242 | ||
P304 | page(s) | 1329-39 | |
P577 | publication date | 2000-12-15 | |
P1433 | published in | Structure | Q15709970 |
P1476 | title | Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates | |
P478 | volume | 8 |
Q26851165 | A brief history of the global effort to develop a preventive HIV vaccine |
Q34398542 | A combinatorial approach toward smart libraries of discontinuous epitopes of HIV gp120 on a TAC synthetic scaffold. |
Q42699474 | A mechanism by which binding of the broadly neutralizing antibody b12 unfolds the inner domain α1 helix in an engineered HIV-1 gp120. |
Q34733504 | A mechanistic understanding of allosteric immune escape pathways in the HIV-1 envelope glycoprotein |
Q33587774 | A non-canonical binding interface in the crystal structure of HIV-1 gp120 core in complex with CD4 |
Q40523804 | A novel assay to identify entry inhibitors that block binding of HIV-1 gp120 to CCR5. |
Q43756667 | A rationally designed synthetic mimic of the discontinuous CD4-binding site of HIV-1 gp120. |
Q34552313 | A single injection of recombinant measles virus vaccines expressing human immunodeficiency virus (HIV) type 1 clade B envelope glycoproteins induces neutralizing antibodies and cellular immune responses to HIV. |
Q35978823 | A small molecule HIV-1 inhibitor that targets the HIV-1 envelope and inhibits CD4 receptor binding |
Q34919985 | A twin-cysteine motif in the V2 region of gp120 is associated with SIV envelope trimer stabilization |
Q24645530 | Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1 |
Q37593189 | Activation and Inactivation of Primary Human Immunodeficiency Virus Envelope Glycoprotein Trimers by CD4-Mimetic Compounds |
Q36423960 | Adaptation of the human immunodeficiency virus type 1 envelope glycoproteins to new world monkey receptors |
Q27640463 | Alternative conformations of HIV-1 V3 loops mimic beta hairpins in chemokines, suggesting a mechanism for coreceptor selectivity |
Q34987062 | An altered and more efficient mechanism of CCR5 engagement contributes to macrophage tropism of CCR5-using HIV-1 envelopes |
Q42086489 | An unrelated monoclonal antibody neutralizes human immunodeficiency virus type 1 by binding to an artificial epitope engineered in a functionally neutral region of the viral envelope glycoproteins |
Q99418269 | Analysis of the SARS-CoV-2 spike protein glycan shield reveals implications for immune recognition |
Q95611861 | Analysis of the SARS-CoV-2 spike protein glycan shield: implications for immune recognition |
Q33223969 | Anti-HIV agents targeting the interaction of gp120 with the cellular CD4 receptor |
Q29547345 | Antibody neutralization and escape by HIV-1 |
Q28256508 | Antibody potency relates to the ability to recognize the closed, pre-fusion form of HIV Env |
Q24536059 | Antibody vs. HIV in a clash of evolutionary titans |
Q42738983 | Antibody-based HIV-1 vaccines: recent developments and future directions |
Q30375834 | Appreciating HIV type 1 diversity: subtype differences in Env. |
Q34121578 | AutoMatch: target-binding protein design and enzyme design by automatic pinpointing potential active sites in available protein scaffolds |
Q33597640 | Automated detection of conformational epitopes using phage display Peptide sequences |
Q34597300 | Back to the future: covalent epitope-based HIV vaccine development |
Q35012342 | Binding of full-length HIV-1 gp120 to CD4 induces structural reorientation around the gp120 core |
Q37237417 | Binding thermodynamics of the N-terminal peptide of the CCR5 coreceptor to HIV-1 envelope glycoprotein gp120 |
Q36525116 | Biochemical and genetic characterizations of a novel human immunodeficiency virus type 1 inhibitor that blocks gp120-CD4 interactions |
Q39240591 | Bioinformatic analysis of neurotropic HIV envelope sequences identifies polymorphisms in the gp120 bridging sheet that increase macrophage-tropism through enhanced interactions with CCR5. |
Q36983858 | Blocking HIV-1 gp120 at the Phe43 cavity: if the extension fits… |
Q36977635 | Broad HIV-1 neutralization mediated by CD4-binding site antibodies |
Q35785010 | Broad-spectrum anti-human immunodeficiency virus (HIV) potential of a peptide HIV type 1 entry inhibitor |
Q36469664 | CD4 binding determinant mimicry for HIV vaccine design |
Q37123579 | CD4+ T cells support production of simian immunodeficiency virus Env antibodies that enforce CD4-dependent entry and shape tropism in vivo |
Q44601067 | CD4-binding site alterations in CCR5-using HIV-1 envelopes influencing gp120-CD4 interactions and fusogenicity |
Q37998496 | Candidate antibody-based therapeutics against HIV-1. |
Q38154038 | Cell-to-cell spread of HIV-1 and evasion of neutralizing antibodies |
Q34232003 | Cell-type-specific aptamer and aptamer-small interfering RNA conjugates for targeted human immunodeficiency virus type 1 therapy |
Q33942996 | Challenges and opportunities for development of an AIDS vaccine |
Q35914362 | Characterization and Implementation of a Diverse Simian Immunodeficiency Virus SIVsm Envelope Panel in the Assessment of Neutralizing Antibody Breadth Elicited in Rhesus Macaques by Multimodal Vaccines Expressing the SIVmac239 Envelope. |
Q34432690 | Characterization of a discontinuous epitope of the HIV envelope protein gp120 recognized by a human monoclonal antibody using chemical modification and mass spectrometric analysis. |
Q33717477 | Characterization of gp120 and its single-chain derivatives, gp120-CD4D12 and gp120-M9: implications for targeting the CD4i epitope in human immunodeficiency virus vaccine design |
Q47610272 | Characterization of the conformational state and flexibility of HIV-1 glycoprotein gp120 core domain |
Q41493875 | Characterization of the multiple conformational States of free monomeric and trimeric human immunodeficiency virus envelope glycoproteins after fixation by cross-linker |
Q37596552 | Characterization of the outer domain of the gp120 glycoprotein from human immunodeficiency virus type 1 |
Q35857408 | Clade-specific differences between human immunodeficiency virus type 1 clades B and C: diversity and correlations in C3-V4 regions of gp120. |
Q35844799 | Coevolution Analysis of HIV-1 Envelope Glycoprotein Complex |
Q27651139 | Combinatorial Optimization of a CD4-Mimetic Miniprotein and Cocrystal Structures with HIV-1 gp120 Envelope Glycoprotein |
Q27303608 | Computational Refinement and Validation Protocol for Proteins with Large Variable Regions Applied to Model HIV Env Spike in CD4 and 17b Bound State |
Q39195226 | Computational studies identifying entry inhibitor scaffolds targeting the Phe43 cavity of HIV-1 gp120. |
Q35069459 | Conformational alterations in the CD4 binding cavity of HIV-1 gp120 influencing gp120-CD4 interactions and fusogenicity of HIV-1 envelopes derived from brain and other tissues |
Q34934438 | Conformational and structural features of HIV-1 gp120 underlying the dual receptor antagonism by cross-reactive neutralizing antibody m18 |
Q34020606 | Conformational characterization of aberrant disulfide-linked HIV-1 gp120 dimers secreted from overexpressing cells. |
Q79968255 | Conservation of inner domain modules in the surface envelope glycoproteins of an ancient rabbit lentivirus and extant lentiviruses and betaretroviruses |
Q34301728 | Consistent patterns of change during the divergence of human immunodeficiency virus type 1 envelope from that of the inoculated virus in simian/human immunodeficiency virus-infected macaques |
Q36499053 | Cost-effective production of a vaginal protein microbicide to prevent HIV transmission. |
Q30421172 | Creating a community resource for protein science |
Q45406845 | Critical role of Arg59 in the high-affinity gp120-binding region of CD4 for human immunodeficiency virus type 1 infection |
Q35536516 | Crystal structure of a fully glycosylated HIV-1 gp120 core reveals a stabilizing role for the glycan at Asn262. |
Q27639371 | Crystal structure of a human rhinovirus that displays part of the HIV-1 V3 loop and induces neutralizing antibodies against HIV-1 |
Q42031529 | Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity |
Q37356010 | Derivation and characterization of a simian immunodeficiency virus SIVmac239 variant with tropism for CXCR4. |
Q36057328 | Design and characterization of a peptide mimotope of the HIV-1 gp120 bridging sheet |
Q34094476 | Design of a non-glycosylated outer domain-derived HIV-1 gp120 immunogen that binds to CD4 and induces neutralizing antibodies |
Q40430180 | Design, expression, and immunogenicity of a soluble HIV trimeric envelope fragment adopting a prefusion gp41 configuration |
Q34626673 | Design, synthesis and biological evaluation of small molecule inhibitors of CD4-gp120 binding based on virtual screening |
Q36279073 | Determination of protein-derived epitopes by mass spectrometry |
Q55508034 | Differential functional phenotypes of two primary HIV-1 strains resulting from homologous point mutations in the LLP domains of the envelope gp41 intracytoplasmic domain. |
Q38090682 | Discovery of ABT-263, a Bcl-family protein inhibitor: observations on targeting a large protein-protein interaction |
Q27646546 | Discovery of Leukotriene A4 Hydrolase Inhibitors Using Metabolomics Biased Fragment Crystallography † |
Q33780620 | Discovery of small-molecule human immunodeficiency virus type 1 entry inhibitors that target the gp120-binding domain of CD4. |
Q34401027 | Disulfide bond that constrains the HIV-1 gp120 V3 domain is cleaved by thioredoxin |
Q26772129 | Dynamic Viral Glycoprotein Machines: Approaches for Probing Transient States That Drive Membrane Fusion |
Q79387613 | Dynamic domains and geometrical properties of HIV-1 gp120 during conformational changes induced by CD4 binding |
Q39314021 | Efficiency of bridging-sheet recruitment explains HIV-1 R5 envelope glycoprotein sensitivity to soluble CD4 and macrophage tropism |
Q30499561 | Electron tomography analysis of envelope glycoprotein trimers on HIV and simian immunodeficiency virus virions |
Q35062926 | Enhanced dynamics of HIV gp120 glycoprotein by small molecule binding |
Q27641982 | Enhancing protein crystallization through precipitant synergy |
Q40311336 | Entropy calculation of HIV-1 Env gp120, its receptor CD4, and their complex: an analysis of configurational entropy changes upon complexation |
Q33839485 | Envelope glycoprotein determinants of neutralization resistance in a simian-human immunodeficiency virus (SHIV-HXBc2P 3.2) derived by passage in monkeys |
Q36155555 | Envelope variable region 4 is the first target of neutralizing antibodies in early simian immunodeficiency virus mac251 infection of rhesus monkeys |
Q42959357 | Epitopes for broad and potent neutralizing antibody responses during chronic infection with human immunodeficiency virus type 1. |
Q33504599 | Escape from autologous neutralizing antibodies in acute/early subtype C HIV-1 infection requires multiple pathways |
Q45611333 | Evidence for Selection of more Adapted Human Immunodeficiency Virus Type 1 Recombinant Strains in a Dually Infected Transfusion Recipient |
Q30157538 | Evolution rescues folding of human immunodeficiency virus-1 envelope glycoprotein GP120 lacking a conserved disulfide bond |
Q37596817 | Evolutionary dynamics of the glycan shield of the human immunodeficiency virus envelope during natural infection and implications for exposure of the 2G12 epitope |
Q36802333 | Exploiting the defensive sugars of HIV-1 for drug and vaccine design |
Q21090507 | Few and far between: how HIV may be evading antibody avidity |
Q28217208 | Fine mapping of the interaction of neutralizing and nonneutralizing monoclonal antibodies with the CD4 binding site of human immunodeficiency virus type 1 gp120. |
Q36386536 | Fluctuation dynamics analysis of gp120 envelope protein reveals a topologically based communication network |
Q42712576 | Fold recognition of the human immunodeficiency virus type 1 V3 loop and flexibility of its crown structure during the course of adaptation to a host |
Q33780529 | Functional chimeras of human immunodeficiency virus type 1 Gp120 and influenza A virus (H3) hemagglutinin |
Q39365770 | Functional evolution of the HIV-1 envelope glycoprotein 120 association site of glycoprotein 41. |
Q33780450 | Functional mimicry of a human immunodeficiency virus type 1 coreceptor by a neutralizing monoclonal antibody |
Q53853233 | Fusion/entry inhibitors as therapies for HIV. |
Q33719511 | Genetic signatures in the envelope glycoproteins of HIV-1 that associate with broadly neutralizing antibodies |
Q92766714 | Glycosylation of viral surface proteins probed by mass spectrometry |
Q28296162 | HIV entry inhibitors: mechanisms of action and resistance pathways |
Q60920348 | HIV vaccines: Biological and clinical considerations |
Q34864743 | HIV-1 envelope accessible surface and polarity: clade, blood, and brain |
Q27011248 | HIV-1 envelope glycoprotein structure |
Q29619017 | HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites |
Q28086826 | HIV-1 gp120 as a therapeutic target: navigating a moving labyrinth |
Q41823383 | HIV-2 neutralization by intact V3-specific Fab fragments |
Q26766153 | Harnessing the protective potential of HIV-1 neutralizing antibodies |
Q27679031 | Heavy Chain-Only IgG2b Llama Antibody Effects Near-Pan HIV-1 Neutralization by Recognizing a CD4-Induced Epitope That Includes Elements of Coreceptor- and CD4-Binding Sites |
Q38328705 | Heparan sulfate targets the HIV-1 envelope glycoprotein gp120 coreceptor binding site. |
Q37179996 | Highly complex neutralization determinants on a monophyletic lineage of newly transmitted subtype C HIV-1 Env clones from India |
Q45463275 | Highly conserved beta16/beta17 beta-hairpin structure in human immunodeficiency virus type 1 YU2 gp120 is critical for CCR5 binding |
Q38014473 | Human immunodeficiency virus-1 gp120 V3 loop for anti-acquired immune deficiency syndrome drug discovery: computer-aided approaches to the problem solving |
Q24679395 | Hyperglycosylated Mutants of Human Immunodeficiency Virus (HIV) Type 1 Monomeric gp120 as Novel Antigens for HIV Vaccine Design |
Q39668082 | Identification and characterization of an immunogenic hybrid epitope formed by both HIV gp120 and human CD4 proteins |
Q53851964 | Identification of N-phenyl-N'-(2,2,6,6-tetramethyl-piperidin-4-yl)-oxalamides as a new class of HIV-1 entry inhibitors that prevent gp120 binding to CD4. |
Q47566053 | Identification of novel structural determinants in MW965 Env that regulate the neutralization phenotype and conformational masking potential of primary HIV-1 isolates |
Q33984371 | Identification of two N-linked glycosylation sites within the core of the simian immunodeficiency virus glycoprotein whose removal enhances sensitivity to soluble CD4. |
Q35708836 | Identifying epitopes of HIV-1 that induce protective antibodies |
Q44646864 | Immunofocusing: antigen engineering to promote the induction of HIV-neutralizing antibodies |
Q33262275 | Immunogenicity of a polyvalent HIV-1 candidate vaccine based on fourteen wild type gp120 proteins in golden hamsters |
Q40561855 | Impact of mutations in the coreceptor binding site on human immunodeficiency virus type 1 fusion, infection, and entry inhibitor sensitivity |
Q34529347 | In vivo patterns of resistance to the HIV attachment inhibitor BMS-488043. |
Q33392865 | Inducing cross-clade neutralizing antibodies against HIV-1 by immunofocusing |
Q33725711 | Influence of disulfide-stabilized structure on the specificity of helper T-cell and antibody responses to HIV envelope glycoprotein gp120 |
Q33614605 | Influence of novel CD4 binding-defective HIV-1 envelope glycoprotein immunogens on neutralizing antibody and T-cell responses in nonhuman primates |
Q47118310 | Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations |
Q35221774 | Insight derived from molecular dynamics simulations into molecular motions, thermodynamics and kinetics of HIV-1 gp120 |
Q34490720 | Insights into the structure, correlated motions, and electrostatic properties of two HIV-1 gp120 V3 loops |
Q28543396 | Integrated analysis of residue coevolution and protein structures capture key protein sectors in HIV-1 proteins |
Q59358743 | Interdomain Stabilization Impairs CD4 Binding and Improves Immunogenicity of the HIV-1 Envelope Trimer |
Q27678341 | Interfacial Cavity Filling To Optimize CD4–Mimetic Miniprotein Interactions with HIV-1 Surface Glycoprotein |
Q34885869 | Isolate-specific differences in the conformational dynamics and antigenicity of HIV-1 gp120. |
Q33740100 | Large-scale conformational sampling of proteins using temperature-accelerated molecular dynamics |
Q34120786 | Local conformational stability of HIV-1 gp120 in unliganded and CD4-bound states as defined by amide hydrogen/deuterium exchange |
Q37010292 | Localized changes in the gp120 envelope glycoprotein confer resistance to human immunodeficiency virus entry inhibitors BMS-806 and #155. |
Q34792976 | Longitudinal Analysis of CCR5 and CXCR4 Usage in a Cohort of Antiretroviral Therapy-Naïve Subjects with Progressive HIV-1 Subtype C Infection. |
Q54246851 | Mapping mutational effects along the evolutionary landscape of HIV envelope. |
Q81155966 | Mechanism of membrane fusion by viral envelope proteins |
Q33269695 | Mimotopes selected with antibodies from HIV-1-neutralizing long-term non-progressor plasma |
Q40484043 | Modified HIV envelope proteins with enhanced binding to neutralizing monoclonal antibodies |
Q41137332 | Molecular construction of HIV-gp120 discontinuous epitope mimics by assembly of cyclic peptides on an orthogonal alkyne functionalized TAC-scaffold. |
Q57897038 | Molecular mechanism of HIV-1 gp120 mutations that reduce CD4 binding affinity |
Q44649287 | Molecular motions of human HIV-1 gp120 envelope glycoproteins |
Q21559473 | Molecular recognition of CCR5 by an HIV-1 gp120 V3 loop |
Q24616040 | Molecular recognition of CXCR4 by a dual tropic HIV-1 gp120 V3 loop |
Q35066154 | Monoclonal antibodies for the structural analysis of the Na+/H+ antiporter NhaA from Escherichia coli |
Q34347265 | Mutagenic stabilization and/or disruption of a CD4-bound state reveals distinct conformations of the human immunodeficiency virus type 1 gp120 envelope glycoprotein |
Q42219237 | NMR observation of HIV-1 gp120 conformational flexibility resulting from V3 truncation |
Q30989881 | NMR structural analysis of a peptide mimic of the bridging sheet of HIV-1 gp120 in methanol and water |
Q33733243 | Naturally occurring variability in the envelope glycoprotein of HIV-1 and development of cell entry inhibitors |
Q39704592 | Neutralization efficiency is greatly enhanced by bivalent binding of an antibody to epitopes in the V4 region and the membrane-proximal external region within one trimer of human immunodeficiency virus type 1 glycoproteins |
Q36843543 | Neutralization of HIV-1 by redirection of natural antibodies |
Q37059618 | Neutralization of Infectivity of Diverse R5 Clinical Isolates of Human Immunodeficiency Virus Type 1 by gp120-Binding 2′F-RNA Aptamers |
Q35857268 | Neutralizing antibody responses in acute human immunodeficiency virus type 1 subtype C infection |
Q35745453 | Novel CD4-Based Bispecific Chimeric Antigen Receptor Designed for Enhanced Anti-HIV Potency and Absence of HIV Entry Receptor Activity |
Q37305770 | Novel dual inhibitory function aptamer-siRNA delivery system for HIV-1 therapy |
Q43124783 | Optimization of human immunodeficiency virus type 1 envelope glycoproteins with V1/V2 deleted, using virus evolution |
Q41965065 | Peptides presenting the binding site of human CD4 for the HIV-1 envelope glycoprotein gp120. |
Q38189746 | Physicochemical bases for protein folding, dynamics, and protein-ligand binding |
Q44567176 | Picking the lock with a hairpin. Did HIV-1 learn the art from chemokines? |
Q34374835 | Plasma IgG to linear epitopes in the V2 and V3 regions of HIV-1 gp120 correlate with a reduced risk of infection in the RV144 vaccine efficacy trial |
Q30360451 | Production and characterization of monoclonal antibodies sensitive to conformation in the 5HT2c serotonin receptor. |
Q34453555 | Progress in targeting HIV-1 entry. |
Q37572718 | Protein dynamics and motions in relation to their functions: several case studies and the underlying mechanisms |
Q37950254 | Protein intrinsic disorder as a flexible armor and a weapon of HIV-1. |
Q35199283 | Putative rhesus macaque germline predecessors of human broadly HIV-neutralizing antibodies: differences from the human counterparts and implications for HIV-1 vaccine development |
Q40325417 | Quaternary contact in the initial interaction of CD4 with the HIV-1 envelope trimer |
Q33640144 | R5 clade C SHIV strains with tier 1 or 2 neutralization sensitivity: tools to dissect env evolution and to develop AIDS vaccines in primate models |
Q36811996 | Range of CD4-Bound Conformations of HIV-1 gp120, as Defined Using Conditional CD4-Induced Antibodies |
Q34342950 | Rapid progression to simian AIDS can be accompanied by selection of CD4-independent gp120 variants with impaired ability to bind CD4. |
Q34174815 | Rational design and characterization of the novel, broad and potent bispecific HIV-1 neutralizing antibody iMabm36. |
Q45052086 | Rational design of a CD4 mimic that inhibits HIV-1 entry and exposes cryptic neutralization epitopes |
Q34042642 | Recurrent signature patterns in HIV-1 B clade envelope glycoproteins associated with either early or chronic infections |
Q27642457 | Recurring conformation of the human immunodeficiency virus type 1 gp120 V3 loop |
Q40204965 | Resistance of HIV-1 to the broadly HIV-1-neutralizing, anti-carbohydrate antibody 2G12. |
Q38774625 | Restraining the conformation of HIV-1 gp120 by removing a flexible loop |
Q40638638 | Role of the gp120 inner domain beta-sandwich in the interaction between the human immunodeficiency virus envelope glycoprotein subunits |
Q88314365 | Roles of conserved tryptophans in trimerization of HIV-1 membrane-proximal external regions: Implications for virucidal design via alchemical free-energy molecular simulations |
Q31112205 | Scaffold optimization in discontinuous epitope containing protein mimics of gp120 using smart libraries |
Q37002237 | Small-molecule CD4 mimics interact with a highly conserved pocket on HIV-1 gp120. |
Q36299747 | Spontaneous rearrangement of the β20/β21 strands in simulations of unliganded HIV-1 glycoprotein, gp120 |
Q47342775 | Stability and Water Accessibility of the Trimeric Membrane Anchors of the HIV-1 Envelope Spikes. |
Q35857416 | Stability of a receptor-binding active human immunodeficiency virus type 1 recombinant gp140 trimer conferred by intermonomer disulfide bonding of the V3 loop: differential effects of protein disulfide isomerase on CD4 and coreceptor binding |
Q34361680 | Stabilization of the soluble, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1. |
Q34299053 | Stabilized HIV-1 envelope glycoprotein trimers lacking the V1V2 domain, obtained by virus evolution |
Q28534454 | Stabilizing exposure of conserved epitopes by structure guided insertion of disulfide bond in HIV-1 envelope glycoprotein |
Q92482128 | Strain-Dependent Activation and Inhibition of Human Immunodeficiency Virus Entry by a Specific PF-68742 Stereoisomer |
Q40796326 | Structural Basis for Species Selectivity in the HIV-1 gp120-CD4 Interaction: Restoring Affinity to gp120 in Murine CD4 Mimetic Peptides |
Q27658449 | Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120 |
Q30393415 | Structural analysis of a highly glycosylated and unliganded gp120-based antigen using mass spectrometry |
Q27643185 | Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120 |
Q38288521 | Structural characterization of a 2'F-RNA aptamer that binds a HIV-1 SU glycoprotein, gp120. |
Q34064787 | Structural determinants for affinity enhancement of a dual antagonist peptide entry inhibitor of human immunodeficiency virus type-1. |
Q56790128 | Structural dynamics of V3 loop with different electrostatics: implications on co-receptor recognition: a molecular dynamics study of HIV gp120 |
Q62572413 | Structural elements of primary CCR5-using HIV-1 gp120 proteins influencing sensitivity and resistance to the broadly neutralizing monoclonal antibody b12 |
Q21131394 | Structural mechanism of trimeric HIV-1 envelope glycoprotein activation |
Q27327645 | Structural plasticity and conformational transitions of HIV envelope glycoprotein gp120 |
Q41972387 | Structure and design of broadly-neutralizing antibodies against HIV. |
Q36856960 | Structure and function of the HIV envelope glycoprotein as entry mediator, vaccine immunogen, and target for inhibitors |
Q27649247 | Structure of Antibody F425-B4e8 in Complex with a V3 Peptide Reveals a New Binding Mode for HIV-1 Neutralization |
Q27644478 | Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9 |
Q27658989 | Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility |
Q29619014 | Structure of a V3-containing HIV-1 gp120 core |
Q27660384 | Structure of a clade C HIV-1 gp120 bound to CD4 and CD4-induced antibody reveals anti-CD4 polyreactivity |
Q34045535 | Structure of the Fab fragment of F105, a broadly reactive anti-human immunodeficiency virus (HIV) antibody that recognizes the CD4 binding site of HIV type 1 gp120. |
Q42882532 | Structure of trimeric HIV-1 envelope glycoproteins. |
Q27678493 | Structure-Based Design, Synthesis, and Characterization of Dual Hotspot Small-Molecule HIV-1 Entry Inhibitors |
Q36868014 | Structure-activity relationships in the binding of chemically derivatized CD4 to gp120 from human immunodeficiency virus |
Q30358736 | Structure-based design, synthesis and validation of CD4-mimetic small molecule inhibitors of HIV-1 entry: conversion of a viral entry agonist to an antagonist. |
Q44572417 | Structure-based, targeted deglycosylation of HIV-1 gp120 and effects on neutralization sensitivity and antibody recognition. |
Q34128200 | Structure-guided design and immunological characterization of immunogens presenting the HIV-1 gp120 V3 loop on a CTB scaffold. |
Q37704735 | Subtype-specific conservation of isoleucine 309 in the envelope V3 domain is linked to immune evasion in subtype C HIV-1 infection |
Q93085697 | Synthesis of Modular Building Blocks using Glycosyl Phosphate Donors for the Construction of Asymmetric N-Glycans |
Q42323642 | Systematic protein-protein docking and molecular dynamics studies of HIV-1 gp120 and CD4: insights for new drug development |
Q34485260 | The B cell response is redundant and highly focused on V1V2 during early subtype C infection in a Zambian seroconverter |
Q21559515 | The SIV surface spike imaged by electron tomography: one leg or three? |
Q34342352 | The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1-->2 mannose residues on the outer face of gp120. |
Q39686562 | The crown and stem of the V3 loop play distinct roles in human immunodeficiency virus type 1 envelope glycoprotein interactions with the CCR5 coreceptor |
Q36155396 | The development of CD4 binding site antibodies during HIV-1 infection |
Q39259705 | The evolutionary significance of certain amino acid substitutions and their consequences for HIV-1 immunogenicity toward HLA's A*0201 and B*27. |
Q36607016 | The highly conserved layer-3 component of the HIV-1 gp120 inner domain is critical for CD4-required conformational transitions. |
Q37099851 | The human immunodeficiency virus type 1 envelope spike of primary viruses can suppress antibody access to variable regions |
Q37667754 | The implications of patterns in HIV diversity for neutralizing antibody induction and susceptibility. |
Q33566030 | The importance of being flexible: the case of basic region leucine zipper transcriptional regulators |
Q37428017 | The integrin alpha4beta7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1. |
Q44433968 | The investigations on HIV-1 gp120 bound with BMS-488043 by using docking and molecular dynamics simulations |
Q34341843 | The mannose-dependent epitope for neutralizing antibody 2G12 on human immunodeficiency virus type 1 glycoprotein gp120. |
Q45662866 | The prolonged culture of human immunodeficiency virus type 1 in primary lymphocytes increases its sensitivity to neutralization by soluble CD4. |
Q33953062 | The role of the third beta strand in gp120 conformation and neutralization sensitivity of the HIV-1 primary isolate DH012 |
Q30430240 | Three-Dimensional Visualizations in Teaching Genomics and Bioinformatics: Mutations in HIV Envelope Proteins and Their Consequences for Vaccine Design. |
Q37612615 | Tyrosine sulfation in the second variable loop (V2) of HIV-1 gp120 stabilizes V2-V3 interaction and modulates neutralization sensitivity |
Q37221499 | Tyrosine-sulfated V2 peptides inhibit HIV-1 infection via coreceptor mimicry. |
Q41932027 | Unique binding modes for the broad neutralizing activity of single-chain variable fragments (scFv) targeting CD4-induced epitopes |
Q35857683 | Unique mutational patterns in the envelope alpha 2 amphipathic helix and acquisition of length in gp120 hypervariable domains are associated with resistance to autologous neutralization of subtype C human immunodeficiency virus type 1. |
Q27678226 | Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops |
Q30480515 | Use of the quartz crystal microbalance to monitor ligand-induced conformational rearrangements in HIV-1 envelope protein gp120. |
Q35103647 | Vaccine for AIDS and Ebola virus infection |
Q34332708 | Vaccines for the prevention of HIV-1 disease |
Q33707333 | Variants of human immunodeficiency virus type 1 that efficiently use CCR5 lacking the tyrosine-sulfated amino terminus have adaptive mutations in gp120, including loss of a functional N-glycan |
Q27676728 | Viral Escape from Neutralizing Antibodies in Early Subtype A HIV-1 Infection Drives an Increase in Autologous Neutralization Breadth |
Q35192660 | epitopes immediately below the base of the V3 loop of gp120 as targets for the initial autologous neutralizing antibody response in two HIV-1 subtype B-infected individuals |
Q33348658 | sCD4-17b bifunctional protein: extremely broad and potent neutralization of HIV-1 Env pseudotyped viruses from genetically diverse primary isolates |
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