Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates

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Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0969-2126(00)00547-5
P3181OpenCitations bibliographic resource ID4745236
P698PubMed publication ID11188697

P50authorJoseph SodroskiQ64524473
Peter D. KwongQ68690794
Richard T. WyattQ96247131
P2093author name stringW A Hendrickson
J Robinson
R W Sweet
S Majeed
P2860cites workBiologically diverse molecular variants within a single HIV-1 isolateQ57998184
Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)Q22242256
The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and ImmunogensQ22242262
HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled ReceptorQ22242268
Identification of a major co-receptor for primary isolates of HIV-1Q22251282
Energetics of the HIV gp120-CD4 binding reactionQ22254716
Dimeric association and segmental variability in the structure of human CD4Q24324340
Improved methods for building protein models in electron density maps and the location of errors in these modelsQ26776980
Crystallography & NMR System: A New Software Suite for Macromolecular Structure DeterminationQ26778405
MOLSCRIPT: a program to produce both detailed and schematic plots of protein structuresQ26778412
Processing of X-ray diffraction data collected in oscillation modeQ26778468
Structural studies of two rhinovirus serotypes complexed with fragments of their cellular receptorQ27620392
Structural analysis of the mechanism of adenovirus binding to its human cellular receptor, CARQ27620424
Interaction of the poliovirus receptor with poliovirusQ27620834
Structures of an HIV and MHC binding fragment from human CD4 as refined in two crystal latticesQ27730898
Kinetic and structural analysis of mutant CD4 receptors that are defective in HIV gp120 bindingQ27734294
Core structure of gp41 from the HIV envelope glycoproteinQ27736064
Atomic structure of the ectodomain from HIV-1 gp41Q27738021
Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibodyQ27759364
Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbonsQ27861091
A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactorsQ28118386
The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirusQ28259668
The antigenic structure of the HIV gp120 envelope glycoproteinQ28274698
The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolatesQ28282895
Structure of a human common cold virus and functional relationship to other picornavirusesQ28286689
CC CKR5: a RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1Q28646859
A conserved HIV gp120 glycoprotein structure involved in chemokine receptor bindingQ28646883
Frequent Detection and Isolation of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and at Risk for AIDSQ29614260
HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5Q29616094
AMoRe: an automated package for molecular replacementQ29642803
Atomic structure of a fragment of human CD4 containing two immunoglobulin-like domainsQ30195771
Three-dimensional structure of poliovirus at 2.9 A resolution.Q30196273
Molecular characterization of biologically diverse envelope variants of human immunodeficiency virus type 1 derived from an individualQ33379671
Neutralization of human immunodeficiency virus type 1 by antibody to gp120 is determined primarily by occupancy of sites on the virion irrespective of epitope specificityQ33782556
Oligomeric modeling and electrostatic analysis of the gp120 envelope glycoprotein of human immunodeficiency virusQ33797989
The level of CD4 expression limits infection of primary rhesus monkey macrophages by a T-tropic simian immunodeficiency virus and macrophagetropic human immunodeficiency virusesQ33826504
Why protein crystals favour some space-groups over othersQ34400973
Crystal structure of an HIV-binding recombinant fragment of human CD4.Q34637157
Replicative function and neutralization sensitivity of envelope glycoproteins from primary and T-cell line-passaged human immunodeficiency virus type 1 isolates.Q35841780
Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured human brain tissue: identification of replication-competent and -defective viral genomesQ36796806
Three-dimensional structure of poliovirus receptor bound to poliovirusQ37141992
Envelope proteins from clinical isolates of human immunodeficiency virus type 1 that are refractory to neutralization by soluble CD4 possess high affinity for the CD4 receptorQ37588188
Rapid selection for an N-linked oligosaccharide by monoclonal antibodies directed against the V3 loop of human immunodeficiency virus type 1.Q38359755
HIV-1-induced cell fusion is mediated by multiple regions within both the viral envelope and the CCR-5 co-receptorQ38908745
The V3 domain of the HIV-1 gp120 envelope glycoprotein is critical for chemokine-mediated blockade of infectionQ38949380
Identification of envelope V3 loop as the major determinant of CD4 neutralization sensitivity of HIV-1.Q39090313
Intrapatient variability of HIV type 1 group O ANT70 during a 10-year follow-up.Q39101418
Determinants of human immunodeficiency virus type 1 envelope glycoprotein activation by soluble CD4 and monoclonal antibodiesQ39579260
V2 loop glycosylation of the human immunodeficiency virus type 1 SF162 envelope facilitates interaction of this protein with CD4 and CCR5 receptors and protects the virus from neutralization by anti-V3 loop and anti-CD4 binding site antibodiesQ39592261
Selection for neutralization resistance of the simian/human immunodeficiency virus SHIVSF33A variant in vivo by virtue of sequence changes in the extracellular envelope glycoprotein that modify N-linked glycosylation.Q39594428
CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5.Q39605077
Regulation of Oxygen Affinity of Hemoglobin: Influence of Structure of the Globin on the Heme IronQ39805445
Neutralization of the human immunodeficiency virus type 1 primary isolate JR-FL by human monoclonal antibodies correlates with antibody binding to the oligomeric form of the envelope glycoprotein complexQ39878965
Critical role of enhanced CD4 affinity in laboratory adaptation of human immunodeficiency virus type 1.Q40870962
The V1/V2 region of human immunodeficiency virus type 1 modulates the sensitivity to neutralization by soluble CD4 and cellular tropismQ41085877
Characterization of envelope and core structural gene products of HTLV-III with sera from AIDS patientsQ41936910
Tyrosine sulfation of the amino terminus of CCR5 facilitates HIV-1 entryQ43694761
Probability analysis of variational crystallization and its application to gp120, the exterior envelope glycoprotein of type 1 human immunodeficiency virus (HIV-1).Q45751477
Major glycoprotein antigens that induce antibodies in AIDS patients are encoded by HTLV-III.Q48378749
Characterization of gp41 as the transmembrane protein coded by the HTLV-III/LAV envelope gene.Q55244821
P433issue12
P921main subjectHIVQ15787
laboratoryQ483242
P304page(s)1329-39
P577publication date2000-12-15
P1433published inStructureQ15709970
P1476titleStructures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates
P478volume8

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Q34485260The B cell response is redundant and highly focused on V1V2 during early subtype C infection in a Zambian seroconverter
Q21559515The SIV surface spike imaged by electron tomography: one leg or three?
Q34342352The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1-->2 mannose residues on the outer face of gp120.
Q39686562The crown and stem of the V3 loop play distinct roles in human immunodeficiency virus type 1 envelope glycoprotein interactions with the CCR5 coreceptor
Q36155396The development of CD4 binding site antibodies during HIV-1 infection
Q39259705The evolutionary significance of certain amino acid substitutions and their consequences for HIV-1 immunogenicity toward HLA's A*0201 and B*27.
Q36607016The highly conserved layer-3 component of the HIV-1 gp120 inner domain is critical for CD4-required conformational transitions.
Q37099851The human immunodeficiency virus type 1 envelope spike of primary viruses can suppress antibody access to variable regions
Q37667754The implications of patterns in HIV diversity for neutralizing antibody induction and susceptibility.
Q33566030The importance of being flexible: the case of basic region leucine zipper transcriptional regulators
Q37428017The integrin alpha4beta7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1.
Q44433968The investigations on HIV-1 gp120 bound with BMS-488043 by using docking and molecular dynamics simulations
Q34341843The mannose-dependent epitope for neutralizing antibody 2G12 on human immunodeficiency virus type 1 glycoprotein gp120.
Q45662866The prolonged culture of human immunodeficiency virus type 1 in primary lymphocytes increases its sensitivity to neutralization by soluble CD4.
Q33953062The role of the third beta strand in gp120 conformation and neutralization sensitivity of the HIV-1 primary isolate DH012
Q30430240Three-Dimensional Visualizations in Teaching Genomics and Bioinformatics: Mutations in HIV Envelope Proteins and Their Consequences for Vaccine Design.
Q37612615Tyrosine sulfation in the second variable loop (V2) of HIV-1 gp120 stabilizes V2-V3 interaction and modulates neutralization sensitivity
Q37221499Tyrosine-sulfated V2 peptides inhibit HIV-1 infection via coreceptor mimicry.
Q41932027Unique binding modes for the broad neutralizing activity of single-chain variable fragments (scFv) targeting CD4-induced epitopes
Q35857683Unique mutational patterns in the envelope alpha 2 amphipathic helix and acquisition of length in gp120 hypervariable domains are associated with resistance to autologous neutralization of subtype C human immunodeficiency virus type 1.
Q27678226Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops
Q30480515Use of the quartz crystal microbalance to monitor ligand-induced conformational rearrangements in HIV-1 envelope protein gp120.
Q35103647Vaccine for AIDS and Ebola virus infection
Q34332708Vaccines for the prevention of HIV-1 disease
Q33707333Variants of human immunodeficiency virus type 1 that efficiently use CCR5 lacking the tyrosine-sulfated amino terminus have adaptive mutations in gp120, including loss of a functional N-glycan
Q27676728Viral Escape from Neutralizing Antibodies in Early Subtype A HIV-1 Infection Drives an Increase in Autologous Neutralization Breadth
Q35192660epitopes immediately below the base of the V3 loop of gp120 as targets for the initial autologous neutralizing antibody response in two HIV-1 subtype B-infected individuals
Q33348658sCD4-17b bifunctional protein: extremely broad and potent neutralization of HIV-1 Env pseudotyped viruses from genetically diverse primary isolates

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