The development of CD4 binding site antibodies during HIV-1 infection

scientific article

The development of CD4 binding site antibodies during HIV-1 infection is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.00734-12
P932PMC publication ID3416294
P698PubMed publication ID22573869

P50authorMyron S. CohenQ16733099
Barton HaynesQ4865631
Lynn MorrisQ70377150
Sengeziwe SibekoQ72617850
Mark K. LouderQ87913394
Stephen D SchmidtQ89034614
Rebecca M LynchQ90663182
Jennifer L KirchherrQ114406376
Salim Abdool KarimQ18161438
Hanneke SchuitemakerQ28606860
Gary NabelQ29446276
Elin S GrayQ56637089
John R. MascolaQ63302442
David C. MontefioriQ63302725
Georgia D. TomarasQ63663866
P2093author name stringZhi-Yong Yang
Kelly Soderberg
Zelda Euler
Lillian Tran
CHAVI 001 Clinical Team Members
Rebecca Dersimonian
P2860cites workRecombinant human Fab fragments neutralize human type 1 immunodeficiency virus in vitroQ24563642
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Structural definition of a conserved neutralization epitope on HIV-1 gp120Q24655948
Structure-based stabilization of HIV-1 gp120 enhances humoral immune responses to the induced co-receptor binding siteQ27316899
Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolatesQ27629806
Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9Q27644478
Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01Q27663293
Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 BindingQ27670829
Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep SequencingQ27671696
A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan ShieldQ27675032
Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41Q28236154
The antigenic structure of the HIV gp120 envelope glycoproteinQ28274698
Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine targetQ29547347
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Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibodyQ29618366
Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy.Q29619254
Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1Q29619511
Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1Q29619512
Broadly cross-reactive HIV neutralizing human monoclonal antibody Fab selected by sequential antigen panning of a phage display libraryQ31031532
Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individualsQ33526340
Characteristics of the earliest cross-neutralizing antibody response to HIV-1.Q33798076
Isolation of a human anti-HIV gp41 membrane proximal region neutralizing antibody by antigen-specific single B cell sortingQ34042758
A limited number of antibody specificities mediate broad and potent serum neutralization in selected HIV-1 infected individualsQ34047445
Dynamics of HIV viremia and antibody seroconversion in plasma donors: implications for diagnosis and staging of primary HIV infectionQ34228730
Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitopeQ34348303
The immune response during acute HIV-1 infection: clues for vaccine developmentQ34614862
Initial B-cell responses to transmitted human immunodeficiency virus type 1: virion-binding immunoglobulin M (IgM) and IgG antibodies followed by plasma anti-gp41 antibodies with ineffective control of initial viremiaQ34848486
The neutralization breadth of HIV-1 develops incrementally over four years and is associated with CD4+ T cell decline and high viral load during acute infectionQ35076717
Dynamic antibody specificities and virion concentrations in circulating immune complexes in acute to chronic HIV-1 infectionQ35363127
Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestorsQ35382871
Two distinct broadly neutralizing antibody specificities of different clonal lineages in a single HIV-1-infected donor: implications for vaccine designQ35868076
Antibodies to discontinuous or conformationally sensitive epitopes on the gp120 glycoprotein of human immunodeficiency virus type 1 are highly prevalent in sera of infected humansQ36641374
Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120-CD4 bindingQ36649958
Characterization of a discontinuous human immunodeficiency virus type 1 gp120 epitope recognized by a broadly reactive neutralizing human monoclonal antibodyQ36821885
Profiling the specificity of neutralizing antibodies in a large panel of plasmas from patients chronically infected with human immunodeficiency virus type 1 subtypes B and C.Q36974754
Broad HIV-1 neutralization mediated by CD4-binding site antibodiesQ36977635
Factors associated with the development of cross-reactive neutralizing antibodies during human immunodeficiency virus type 1 infectionQ37033294
Analysis of neutralization specificities in polyclonal sera derived from human immunodeficiency virus type 1-infected individualsQ37033400
The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infectionQ37273195
Antibody specificities associated with neutralization breadth in plasma from human immunodeficiency virus type 1 subtype C-infected blood donorsQ37333772
Breadth of neutralizing antibody response to human immunodeficiency virus type 1 is affected by factors early in infection but does not influence disease progressionQ37356036
Mechanism of human immunodeficiency virus type 1 resistance to monoclonal antibody B12 that effectively targets the site of CD4 attachmentQ37410770
Neutralization of HIV-1 by F105, a human monoclonal antibody to the CD4 binding site of gp120.Q41582091
Cross‐Reactive Neutralizing Humoral Immunity Does Not Protect from HIV Type 1 Disease ProgressionQ56886558
P433issue14
P407language of work or nameEnglishQ1860
P921main subjectantibodyQ79460
P304page(s)7588-7595
P577publication date2012-05-09
P1433published inJournal of VirologyQ1251128
P1476titleThe development of CD4 binding site antibodies during HIV-1 infection
P478volume86

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