Structure of a clade C HIV-1 gp120 bound to CD4 and CD4-induced antibody reveals anti-CD4 polyreactivity

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Structure of a clade C HIV-1 gp120 bound to CD4 and CD4-induced antibody reveals anti-CD4 polyreactivity is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1020021914
P356DOI10.1038/NSMB.1796
P932PMC publication ID2949298
P698PubMed publication ID20357769
P5875ResearchGate publication ID42807229

P50authorPamela J. BjorkmanQ2048641
P2093author name stringPaola M Marcovecchio
Ron Diskin
P2860cites workAccess of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1Q24645530
Structural definition of a conserved neutralization epitope on HIV-1 gp120Q24655948
Crystallography & NMR System: A New Software Suite for Macromolecular Structure DeterminationQ26778405
Processing of X-ray diffraction data collected in oscillation modeQ26778468
Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolatesQ27629806
Structures of the CCR5 N Terminus and of a Tyrosine-Sulfated Antibody with HIV-1 gp120 and CD4Q27648643
Matuzumab Binding to EGFR Prevents the Conformational Rearrangement Required for DimerizationQ27650259
Interactions between Lipids and Human Anti-HIV Antibody 4E10 Can Be Reduced without Ablating Neutralizing ActivityQ27658138
Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120Q27658449
Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibodyQ27759364
Coot: model-building tools for molecular graphicsQ27860505
Version 1.2 of the Crystallography and NMR systemQ27860583
Toward the structural genomics of complexes: Crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosisQ27860789
Optimal description of a protein structure in terms of multiple groups undergoing TLS motionQ27860825
Phasercrystallographic softwareQ27860930
Refinement of macromolecular structures by the maximum-likelihood methodQ27861011
The CCP4 suite: programs for protein crystallographyQ27861090
Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41Q28236154
Structure of an unliganded simian immunodeficiency virus gp120 coreQ29616089
Structure of a V3-containing HIV-1 gp120 coreQ29619014
Evaluation of CD4-CD4i antibody architectures yields potent, broadly cross-reactive anti-human immunodeficiency virus reagentsQ33558696
Autoreactivity in an HIV-1 broadly reactive neutralizing antibody variable region heavy chain induces immunologic toleranceQ33591736
Antibodies to CD4 in individuals infected with human immunodeficiency virus type 1.Q33854440
The V1, V2, and V3 regions of the human immunodeficiency virus type 1 envelope differentially affect the viral phenotype in an isolate-dependent mannerQ33883936
Understanding the genetic diversity of HIV-1.Q34087006
Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitopeQ34348303
Genetic and neutralization properties of subtype C human immunodeficiency virus type 1 molecular env clones from acute and early heterosexually acquired infections in Southern AfricaQ35140032
V3: HIV's switch-hitterQ36051661
Antigenic conservation and immunogenicity of the HIV coreceptor binding siteQ36403587
CD4-induced epitopes in the HIV envelope glycoprotein, gp120.Q37017799
Mechanism of human immunodeficiency virus type 1 resistance to monoclonal antibody B12 that effectively targets the site of CD4 attachmentQ37410770
Role of HIV membrane in neutralization by two broadly neutralizing antibodiesQ37453499
Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies.Q40429324
Characterization of CD4-induced epitopes on the HIV type 1 gp120 envelope glycoprotein recognized by neutralizing human monoclonal antibodiesQ40682865
Carbohydrate-binding Agents Cause Deletions of Highly Conserved Glycosylation Sites in HIV GP120Q56763445
Detection of anti-CD4 autoantibodies in the sera of HIV-infected patients using recombinant soluble CD4 moleculesQ67233696
Characterization of new monoclonal antibodies that discriminate between soluble and membrane CD4 and compete with human anti-CD4 autoimmune seraQ73874162
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectstructural biologyQ908902
antibodyQ79460
P304page(s)608-13
P577publication date2010-05-01
P1433published inNature Structural & Molecular BiologyQ1071739
P1476titleStructure of a clade C HIV-1 gp120 bound to CD4 and CD4-induced antibody reveals anti-CD4 polyreactivity
P478volume17