Autoreactivity in an HIV-1 broadly reactive neutralizing antibody variable region heavy chain induces immunologic tolerance

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Autoreactivity in an HIV-1 broadly reactive neutralizing antibody variable region heavy chain induces immunologic tolerance is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2010PNAS..107..181V
P356DOI10.1073/PNAS.0912914107
P932PMC publication ID2806760
P698PubMed publication ID20018688
P5875ResearchGate publication ID40696052

P50authorBarton HaynesQ4865631
Garnett KelsoeQ60614752
Marilyn DiazQ64621170
Hua-Xin LiaoQ88608388
Laurent VerkoczyQ88773002
Munir AlamQ89520930
Hilary Bouton-VervilleQ117248645
Ying-Bin OuyangQ117248646
P2093author name stringT Matt Holl
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Two distinct populations of H chain-edited B cells show differential surrogate L chain dependenceQ33552573
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The role of antibody polyspecificity and lipid reactivity in binding of broadly neutralizing anti-HIV-1 envelope human monoclonal antibodies 2F5 and 4E10 to glycoprotein 41 membrane proximal envelope epitopesQ34610233
In vivo gp41 antibodies targeting the 2F5 monoclonal antibody epitope mediate human immunodeficiency virus type 1 neutralization breadthQ34937404
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Autoreactive B cells in the marginal zone that express dual receptorsQ36369869
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Early preplasma cells define a tolerance checkpoint for autoreactive B cellsQ37006531
Sites and stages of autoreactive B cell activation and regulation.Q37058621
Human immunodeficiency virus type 1 elite neutralizers: individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithmQ37247974
Role of HIV membrane in neutralization by two broadly neutralizing antibodiesQ37453499
Heavy chain-only antibodies are spontaneously produced in light chain-deficient mice.Q40034320
Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies.Q40429324
Genetic and structural evidence for antigen selection of anti-DNA antibodies.Q40661152
Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice.Q41423746
Analysis of the structural correlates for antibody polyreactivity by multiple reassortments of chimeric human immunoglobulin heavy and light chain V segmentsQ41886151
In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. IV. Affinity-dependent, antigen-driven B cell apoptosis in germinal centers as a mechanism for maintaining self-toleranceQ41888015
Breakdown of self-tolerance in anergic B lymphocytes.Q43668436
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectantibodyQ79460
P304page(s)181-186
P577publication date2009-12-14
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleAutoreactivity in an HIV-1 broadly reactive neutralizing antibody variable region heavy chain induces immunologic tolerance
P478volume107

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