| scholarly article | Q13442814 |
| P356 | DOI | 10.1093/EMBOJ/20.20.5543 |
| P8608 | Fatcat ID | release_bmensppsn5bm7gvmeqxrdzwpd4 |
| P932 | PMC publication ID | 125671 |
| P698 | PubMed publication ID | 11597998 |
| P5875 | ResearchGate publication ID | 11752136 |
| P50 | author | Tom Blundell | Q7814993 |
| Daniel Lietha | Q30158438 | ||
| P2093 | author name string | E Gherardi | |
| D Y Chirgadze | |||
| B Mulloy | |||
| P2860 | cites work | Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization | Q24290400 |
| Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin | Q24290496 | ||
| Molecular cloning and expression of human hepatocyte growth factor | Q24305558 | ||
| Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product | Q24310794 | ||
| Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factor | Q24555664 | ||
| "Diabodies": small bivalent and bispecific antibody fragments | Q24562167 | ||
| 3D domain swapping: a mechanism for oligomer assembly | Q24675333 | ||
| Improved methods for building protein models in electron density maps and the location of errors in these models | Q26776980 | ||
| A functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-Met receptor and induces cell dissociation but not mitogenesis | Q37329953 | ||
| Identification and dynamics of a heparin-binding site in hepatocyte growth factor. | Q38318686 | ||
| Structure of a heparan sulphate oligosaccharide that binds to basic fibroblast growth factor | Q38327052 | ||
| Identification of the basic fibroblast growth factor binding sequence in fibroblast heparan sulfate | Q38328648 | ||
| Identification of a Competitive HGF Antagonist Encoded by an Alternative Transcript | Q38332144 | ||
| Hepatocyte growth factor (HGF)/NK1 is a naturally occurring HGF/scatter factor variant with partial agonist/antagonist activity | Q38357454 | ||
| Activation of hepatocyte growth factor by the plasminogen activators uPA and tPA. | Q38507554 | ||
| Frequency of TPR-MET rearrangement in patients with gastric carcinoma and in first-degree relatives | Q40887718 | ||
| Engineered mutants of HGF/SF with reduced binding to heparan sulphate proteoglycans, decreased clearance and enhanced activity in vivo | Q41052630 | ||
| Hepatocyte growth factor/scatter factor-Met signaling in tumorigenicity and invasion/metastasis | Q41188806 | ||
| HGF/SF Inhibits Junctional Communication | Q41317197 | ||
| An alternatively processed mRNA generated from human hepatocyte growth factor gene. | Q41687910 | ||
| Scatter factor is a fibroblast-derived modulator of epithelial cell mobility | Q42807925 | ||
| Hepatocyte growth factor/scatter factor is an axonal chemoattractant and a neurotrophic factor for spinal motor neurons | Q43819365 | ||
| Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas | Q45345804 | ||
| Generation and characterization of a competitive antagonist of human hepatocyte growth factor, HGF/NK1. | Q45998398 | ||
| The branchial arches and HGF are growth-promoting and chemoattractant for cranial motor axons | Q52169915 | ||
| Evidence for non-covalent clusters of the c-met proto-oncogene product | Q54269961 | ||
| Crystalline Structure of Heparin | Q66920922 | ||
| Activation of hepatocyte growth factor by two homologous proteases, blood-coagulation factor XIIa and hepatocyte growth factor activator | Q72221318 | ||
| Hairpin loop and second kringle domain are essential sites for heparin binding and biological activity of hepatocyte growth factor | Q72724935 | ||
| Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination | Q26778405 | ||
| Processing of X-ray diffraction data collected in oscillation mode | Q26778468 | ||
| Crystal structure of human stem cell factor: implication for stem cell factor receptor dimerization and activation | Q27625275 | ||
| Dimer formation through domain swapping in the crystal structure of the Grb2-SH2-Ac-pYVNV complex | Q27627944 | ||
| Crystal structure of a diabody, a bivalent antibody fragment | Q27729940 | ||
| Heparin structure and interactions with basic fibroblast growth factor | Q27732601 | ||
| The solution structure of the N-terminal domain of hepatocyte growth factor reveals a potential heparin-binding site | Q27748909 | ||
| Structure of a heparin-linked biologically active dimer of fibroblast growth factor | Q27760195 | ||
| Crystal structure of the NK1 fragment of human hepatocyte growth factor at 2.0 A resolution | Q27766028 | ||
| Crystal structure of the NK1 fragment of HGF/SF suggests a novel mode for growth factor dimerization and receptor binding | Q27766474 | ||
| Raster3D Version 2.0. A program for photorealistic molecular graphics | Q27860485 | ||
| An extensively modified version of MolScript that includes greatly enhanced coloring capabilities | Q27860594 | ||
| Solvent content of protein crystals | Q27860807 | ||
| The CCP4 suite: programs for protein crystallography | Q27861090 | ||
| Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons | Q27861091 | ||
| Molecular cloning and sequence analysis of the cDNA for a human serine protease reponsible for activation of hepatocyte growth factor. Structural similarity of the protease precursor to blood coagulation factor XII | Q28115845 | ||
| Requirement of heparan sulfate for bFGF-mediated fibroblast growth and myoblast differentiation | Q28296150 | ||
| Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor | Q28307227 | ||
| Scatter factor/hepatocyte growth factor is essential for liver development | Q28504542 | ||
| Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud | Q28506228 | ||
| Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase | Q28589603 | ||
| Defective heparan sulfate biosynthesis and neonatal lethality in mice lacking N-deacetylase/N-sulfotransferase-1 | Q28591609 | ||
| Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor | Q29616189 | ||
| Efficient rebuilding of protein structures. | Q30342571 | ||
| NK1, a Natural Splice Variant of Hepatocyte Growth Factor/Scatter Factor, Is a Partial Agonist In Vivo | Q33772210 | ||
| Cell surface heparan sulfate proteoglycans: selective regulators of ligand-receptor encounters | Q33994817 | ||
| Conformation and dynamics of heparin and heparan sulfate | Q34087654 | ||
| Purification of scatter factor, a fibroblast-derived basic protein that modulates epithelial interactions and movement | Q34294357 | ||
| Interaction of hepatocyte growth factor with heparan sulfate. Elucidation of the major heparan sulfate structural determinants | Q34339506 | ||
| Molecular cloning and sequence analysis of cDNA for human hepatocyte growth factor | Q35307866 | ||
| Heparin induces dimerization and confers proliferative activity onto the hepatocyte growth factor antagonists NK1 and NK2. | Q36236835 | ||
| Molecular evolution and domain structure of plasminogen-related growth factors (HGF/SF and HGF1/MSP) | Q36704207 | ||
| P433 | issue | 20 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | crystal structure | Q895901 |
| P304 | page(s) | 5543-5555 | |
| P577 | publication date | 2001-10-01 | |
| P1433 | published in | The EMBO Journal | Q1278554 |
| P1476 | title | Crystal structures of NK1-heparin complexes reveal the basis for NK1 activity and enable engineering of potent agonists of the MET receptor | |
| P478 | volume | 20 |
| Q27647900 | A mechanistic basis for converting a receptor tyrosine kinase agonist to an antagonist |
| Q27639093 | A new crystal form of the NK1 splice variant of HGF/SF demonstrates extensive hinge movement and suggests that the NK1 dimer originates by domain swapping |
| Q36798972 | Achieving high signal-to-noise in cell regulatory systems: Spatial organization of multiprotein transmembrane assemblies of FGFR and MET receptors. |
| Q37198947 | Adeno-associated virus-2 and its primary cellular receptor--Cryo-EM structure of a heparin complex |
| Q42088207 | An engineered dimeric fragment of hepatocyte growth factor is a potent c-MET agonist |
| Q57918839 | Asymmetry in the Multiprotein Systems of Molecular Biology |
| Q34408270 | BFMP: a method for discretizing and visualizing pyranose conformations |
| Q37750050 | C-MET as a new therapeutic target for the development of novel anticancer drugs |
| Q47280088 | CAR T-cell immunotherapy of MET-expressing malignant mesothelioma |
| Q34068511 | Coupling growth-factor engineering with nanotechnology for therapeutic angiogenesis. |
| Q24294589 | Crystal structure of the HGF beta-chain in complex with the Sema domain of the Met receptor |
| Q24531430 | Crystal structure of the OpcA integral membrane adhesin from Neisseria meningitidis |
| Q27639866 | Crystal structure of the TSP-1 type 1 repeats |
| Q42152415 | Crystal structure of the factor XI zymogen reveals a pathway for transactivation |
| Q31116931 | DMT-MM mediated functionalisation of the non-reducing end of glycosaminoglycans |
| Q38194193 | Demystifying heparan sulfate-protein interactions. |
| Q35677691 | Differential mitogenic effects of single chain hepatocyte growth factor (HGF)/scatter factor and HGF/NK1 following cleavage by factor Xa. |
| Q44701384 | Dissociation of c‐Met phosphotyrosine sites in human cells in response to mouse hepatocyte growth factor but not human hepatocyte growth factor: the possible roles of different amino acids in different species |
| Q34285002 | Docking server for the identification of heparin binding sites on proteins |
| Q34782774 | Drug development of MET inhibitors: targeting oncogene addiction and expedience |
| Q37958625 | Emerging technologies for enabling proangiogenic therapy |
| Q33970874 | Engineering hepatocyte growth factor fragments with high stability and activity as Met receptor agonists and antagonists |
| Q57360231 | Exploring the chemical space of the lysine-binding pocket of the first kringle domain of hepatocyte growth factor/scatter factor (HGF/SF) yields a new class of inhibitors of HGF/SF-MET binding |
| Q36489766 | Extracellular angiogenic growth factor interactions: an angiogenesis interactome survey |
| Q30568524 | Fell-Muir Lecture: Heparan sulphate and the art of cell regulation: a polymer chain conducts the protein orchestra |
| Q34267718 | Functional map and domain structure of MET, the product of the c- met protooncogene and receptor for hepatocyte growth factor/scatter factor |
| Q27677936 | Galactose Recognition by the Apicomplexan Parasite Toxoplasma gondii |
| Q35825233 | Heparin-binding domains in vascular biology |
| Q38292865 | Hepatocyte growth factor/scatter factor binds to small heparin-derived oligosaccharides and stimulates the proliferation of human HaCaT keratinocytes |
| Q40330196 | Interaction of hepatocyte growth factor with gelatin as the carrier material |
| Q46835307 | Interactions of hepatocyte growth factor/scatter factor with various glycosaminoglycans reveal an important interplay between the presence of iduronate and sulfate density. |
| Q39503087 | Intracellular signaling cascades triggered by the NK1 fragment of hepatocyte growth factor in human prostate epithelial cell line PNT1A |
| Q27008925 | MET: A Critical Player in Tumorigenesis and Therapeutic Target |
| Q38318355 | Mapping of heparin/heparan sulfate binding sites on αvβ3 integrin by molecular docking |
| Q28235183 | Met, metastasis, motility and more |
| Q51568879 | Molecular modeling of the interaction between heparan sulfate and cellular growth factors: bringing pieces together |
| Q40461761 | Multiple biological responses are induced by glycosylation-deficient hepatocyte growth factor |
| Q27652688 | NMR Solution Structure of the Neurotrypsin Kringle Domain † ‡ |
| Q38817809 | Oligonucleotide-Based Mimetics of Hepatocyte Growth Factor. |
| Q27675667 | PAN-modular structure of microneme protein SML-2 from the parasite Sarcocystis muris at 1.95 Å resolution and its complex with 1-thio-β-D-galactose |
| Q63359247 | Plasma hepatocyte growth factor as a marker for small-for-gestational age fetuses |
| Q38674666 | Semi-synthesis of a HGF/SF kringle one (K1) domain scaffold generates a potent in vivo MET receptor agonist. |
| Q92782960 | Signalling architectures can prevent cancer evolution |
| Q47374322 | Solution structure of a PAN module from the apicomplexan parasite Eimeria tenella. |
| Q27650132 | Structural and Functional Analysis of Slit and Heparin Binding to Immunoglobulin-like Domains 1 and 2 of Drosophila Robo |
| Q27663368 | Structural basis for agonism and antagonism of hepatocyte growth factor |
| Q38057539 | Structural basis of MET receptor dimerization by the bacterial invasion protein InlB and the HGF/SF splice variant NK1 |
| Q33943794 | Structure of AMA1 from Plasmodium falciparum reveals a clustering of polymorphisms that surround a conserved hydrophobic pocket |
| Q24296700 | Targeted disruption of heparan sulfate interaction with hepatocyte and vascular endothelial growth factors blocks normal and oncogenic signaling |
| Q37792116 | Targeting the MET oncogene in cancer and metastases. |
| Q44504094 | The N-terminal domain of hepatocyte growth factor inhibits the angiogenic behavior of endothelial cells independently from binding to the c-met receptor |
| Q38357819 | The binding properties of minimal oligosaccharides reveal a common heparan sulfate/dermatan sulfate-binding site in hepatocyte growth factor/scatter factor that can accommodate a wide variety of sulfation patterns |
| Q44368469 | The structural biology of growth factor receptor activation |
| Q40926975 | Thiocarbamate-linked polysulfonate-peptide conjugates as selective hepatocyte growth factor receptor binders. |
| Q38974266 | Thrombospondin-1 as a Paradigm for the Development of Antiangiogenic Agents Endowed with Multiple Mechanisms of Action. |
| Q43903883 | Zymogen activation of neurotrypsin and neurotrypsin-dependent agrin cleavage on the cell surface are enhanced by glycosaminoglycans |
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