Role of FGFR2-signaling in the pathogenesis of acne

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Role of FGFR2-signaling in the pathogenesis of acne is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.4161/DERM.1.3.8474
P932PMC publication ID2835907
P698PubMed publication ID20436882
P5875ResearchGate publication ID43535822

P50authorBodo MelnikQ88156770
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The fatty acid synthase gene is a conserved p53 family target from worm to human.Q47069045
What is the pathogenesis of acne?Q47622824
Point mutations throughout the GLI3 gene cause Greig cephalopolysyndactyly syndrome.Q47939552
Hedgehog-GLI signaling regulates the behavior of cells with stem cell properties in the developing neocortex.Q48113249
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The paternal-age effect in Apert syndrome is due, in part, to the increased frequency of mutations in spermQ33906096
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Abuse of anabolic-androgenic steroids and bodybuilding acne: an underestimated health problemQ34002248
Role of hormones in pilosebaceous unit developmentQ34009592
Biochemical analysis of pathogenic ligand-dependent FGFR2 mutations suggests distinct pathophysiological mechanisms for craniofacial and limb abnormalitiesQ34074836
Transducing the hedgehog signalQ34084346
Sprouty2 inhibits the Ras/MAP kinase pathway by inhibiting the activation of Raf.Q34100782
Testosterone formation and metabolism during male sexual differentiation in the human embryoQ34219047
Keratins and the keratinocyte activation cycleQ34248710
Apert syndrome results from localized mutations of FGFR2 and is allelic with Crouzon syndromeQ34308670
Exclusive paternal origin of new mutations in Apert syndromeQ34385938
13-cis Retinoic acid induces apoptosis and cell cycle arrest in human SEB-1 sebocytesQ34507245
Inflammatory events are involved in acne lesion initiationQ34535060
Phosphoinositide 3-kinase and Akt are essential for Sonic Hedgehog signalingQ34574774
The effect of a high-protein, low glycemic-load diet versus a conventional, high glycemic-load diet on biochemical parameters associated with acne vulgaris: a randomized, investigator-masked, controlled trialQ34621172
Gli and hedgehog in cancer: tumours, embryos and stem cells.Q34665999
Retinoic acid embryopathyQ34686260
FGF signaling pathways in endochondral and intramembranous bone development and human genetic diseaseQ34702208
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Cholesterol precursors and facial cleftingQ35009494
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Keratinocyte growth factor is an important endogenous mediator of hair follicle growth, development, and differentiation. Normalization of the nu/nu follicular differentiation defect and amelioration of chemotherapy-induced alopeciaQ35796365
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Hedgehog signaling regulates sebaceous gland developmentQ35843342
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DeltaNp63 regulates thymic development through enhanced expression of FgfR2 and Jag2.Q35901203
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Keratinocyte growth factor receptorsQ36954792
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FGFR2 signaling and the pathogenesis of acneQ37322522
Anti-acne agents attenuate FGFR2 signal transduction in acneQ37395769
Keratinocyte growth factor functions in epithelial induction during seminal vesicle developmentQ37558690
Increased expression of protein kinase Calpha, interleukin-1alpha, and RhoA guanosine 5'-triphosphatase in osteoblasts expressing the Ser252Trp fibroblast growth factor 2 receptor Apert mutation: identification by analysis of complementary DNA microQ38301608
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Identification of genetic pathways activated by the androgen receptor during the induction of proliferation in the ventral prostate gland.Q38348824
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The endocrinology and developmental biology of the prostateQ39669602
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Inhibitors of dipeptidyl peptidase IV and aminopeptidase N target major pathogenetic steps in acne initiationQ40266797
Keratinocyte growth factor promotes melanosome transfer to keratinocytesQ40340103
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Acne vulgaris: proliferative cells in sebaceous glands.Q53680609
Nevus comedonicus.Q53920930
Pro-inflammatory levels of interleukin-1 alpha-like bioactivity are present in the majority of open comedones in acne vulgaris.Q54063556
Androgen Excess in Cystic AcneQ54498771
Pilosebaceous abnormalities in Apert's syndrome.Q54735805
Elevated Serum Insulin‐like Growth Factor‐1 (IGF‐1) Levels in Women with Postadolescent AcneQ55064095
Epidermal mosaicism producing localised acne: somatic mutation in FGFR2Q56263112
RNA interference and inhibition of MEK-ERK signaling prevent abnormal skeletal phenotypes in a mouse model of craniosynostosisQ56333589
What syndrome is this? Apert syndromeQ56333904
Resolution of acne following therapy with an oral contraceptive in a patient with Apert syndromeQ56339315
[Acrocephalosyndactyly I (Apert syndrome)]Q56376583
Isotretinoin therapy for antibiotic-refractory acne in Apert's syndromeQ56378982
Cutaneous manifestations of Apert syndromeQ56384385
Apert's syndrome (acrocephalosyndactyly) in a patient with hyperhidrosisQ56389572
Successful treatment of the acne of Apert syndrome with isotretinoinQ56398153
The acneform eruption of Apertʼs syndrome is not acne vulgarisQ56414698
Acneform eruption in Apert's syndrome. Acrocephalosyn dactylyQ56417590
Apert's syndromeQ56418184
Depigmentation of hair, skin, and eyes associated with the Apert syndromeQ56419091
Pilosebaceous abnormalities in Apert type acrocephalosyndactylyQ56420561
Milk consumption: aggravating factor of acne and promoter of chronic diseases of Western societiesQ56601583
Antimitochondrial effect of saturated medium chain length (C8-C13) dicarboxylic acidsQ62660086
Unilateral segmental acneiform naevus: a model disorder towards understanding fibroblast growth factor receptor 2 function in acne?Q62661447
Interleukin 1 immunoreactivity in sebaceous glandsQ67979908
Effect of alpha-melanocyte-stimulating hormone and testosterone on cutaneous and modified sebaceous glands in the ratQ68214377
5 alpha-dihydrotestosterone formation is necessary for embryogenesis of the rat prostateQ68267260
Sebaceous gland response in man to the administration of testosterone, delta-4-androstenedione, and dehydroisoandrosteroneQ68426845
Cellular dynamics of comedo formation in acne vulgarisQ68486561
Isotretinoin teratogenicity in mouse whole embryo cultureQ68727970
A longitudinal study of the relationship of plasma somatomedin-C concentration to the pubertal growth spurtQ69009079
Androgen receptor in hirsutism and acneQ70023786
On the mechanism of sebaceous secretionQ70576167
Modeling acne in vitroQ70978947
Messenger RNAs for the multifunctional cytokines interleukin-1 alpha, interleukin-1 beta and tumor necrosis factor-alpha are present in adnexal tissues and in dermis of normal human skinQ71017789
Keratin expression in pilosebaceous epithelia in truncal skin of acne patientsQ71362738
Activity of the Type 1 5α-Reductase Exhibits Regional Differences in Isolated Sebaceous Glands and Whole SkinQ71961324
The androgen control of sebum production. Studies of subjects with dihydrotestosterone deficiency and complete androgen insensitivityQ72949275
c-Jun and JunB antagonistically control cytokine-regulated mesenchymal-epidermal interaction in skinQ73291709
Interleukin-1 induces transcription of keratin K6 in human epidermal keratinocytesQ73443704
Naevus comedonicus immunohistochemical features in two casesQ73824992
Keratinocyte growth regulation in defined organotypic cultures through IL-1-induced keratinocyte growth factor expression in resting fibroblastsQ73873179
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectpathogenesisQ372016
P304page(s)141-156
P577publication date2009-05-01
P1433published inDermato-endocrinologyQ26842418
P1476titleRole of FGFR2-signaling in the pathogenesis of acne
P478volume1

Reverse relations

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