FGF2-Heparin co-crystal complex-assisted design of mutants FGF1 and FGF7 with predictable heparin affinities

scientific article published on July 1998

FGF2-Heparin co-crystal complex-assisted design of mutants FGF1 and FGF7 with predictable heparin affinities is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.273.29.18617
P698PubMed publication ID9660835
P5875ResearchGate publication ID13623711

P2093author name stringBurgess WH
Wong P
P2860cites workDNA sequencing with chain-terminating inhibitorsQ22066207
Molecular cloning of a novel cytokine cDNA encoding the ninth member of the fibroblast growth factor family, which has a unique secretion propertyQ24309013
Determination of ligand-binding specificity by alternative splicing: two distinct growth factor receptors encoded by a single geneQ24324199
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
Heparin structure and interactions with basic fibroblast growth factorQ27732601
Rapid and efficient site-specific mutagenesis without phenotypic selectionQ27860608
Use of T7 RNA polymerase to direct expression of cloned genesQ27860692
Keratinocyte growth factor. A fibroblast growth factor family member with unusual target cell specificityQ28237173
Three-Dimensional Structures of Acidic and Basic Fibroblast Growth FactorsQ28267322
Human endothelial cell growth factor: cloning, nucleotide sequence, and chromosome localizationQ28299741
[21] Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reactionQ29544077
Possible dissociation of the heparin-binding and mitogenic activities of heparin-binding (acidic fibroblast) growth factor-1 from its receptor-binding activities by site-directed mutagenesis of a single lysine residueQ36223955
Interaction of endothelial cell growth factor with heparin: characterization by receptor and antibody recognitionQ37541922
The heparin-binding (fibroblast) growth factor family of proteinsQ38286731
Interaction of fibroblast growth factor-1 and related peptides with heparan sulfate and its oligosaccharidesQ38342270
Two hierarchies of FGF-2 signaling in heparin: mitogenic stimulation and high-affinity binding/receptor transphosphorylation.Q38353810
Structure-function studies of FGF-1: dissociation and partial reconstitution of certain of its biological activitiesQ40395648
Internalization of basic fibroblast growth factor (bFGF) in cultured endothelial cells: role of the low affinity heparin-like bFGF receptors.Q41581807
Effect of heparin on the binding affinity of acidic FGF for the cloned human FGF receptors, flg and bekQ41718353
Structure-function studies of heparin-binding (acidic fibroblast) growth factor-1 using site-directed mutagenesisQ41881717
Potentiation of Balb/3T3 fibroblast proliferative response by interleukin-1 and epidermal growth factorQ42803986
Reductive methylation of lysine residues in acidic fibroblast growth factor: effect on mitogenic activity and heparin affinityQ42805087
Analysis of putative heparin-binding domains of fibroblast growth factor-1. Using site-directed mutagenesis and peptide analogues.Q42823294
Heparin protects heparin-binding growth factor-I from proteolytic inactivation in vitroQ44656846
Structure and expression of the rat mRNA encoding a novel member of the fibroblast growth factor familyQ48062267
Thrombin inactivates acidic fibroblast growth factor but not basic fibroblast growth factorQ48088817
Heparin protects basic and acidic FGF from inactivationQ68895706
Stabilization by heparin of acidic fibroblast growth factor mitogenicity for human endothelial cells in vitroQ69723398
Differences in the interaction of heparin with arginine and lysine and the importance of these basic amino acids in the binding of heparin to acidic fibroblast growth factorQ71557714
Keratinocyte growth factor and fibroblast growth factor action on DNA synthesis in rat and human hepatocytes: modulation by heparinQ71608310
Multivalent Ligand-Receptor Binding Interactions in the Fibroblast Growth Factor System Produce a Cooperative Growth Factor and Heparin Mechanism for Receptor DimerizationQ71642294
Heparin-induced self-association of fibroblast growth factor-2. Evidence for two oligomerization processesQ73442763
P433issue29
P407language of work or nameEnglishQ1860
P304page(s)18617-18622
P577publication date1998-07-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleFGF2-Heparin co-crystal complex-assisted design of mutants FGF1 and FGF7 with predictable heparin affinities
P478volume273

Reverse relations

Q24314621Fine mapping of the sequences in domain 5 of high molecular weight kininogen (HK) interacting with heparin and zinccites workP2860

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