Synthesis and binding mode of heterocyclic analogues of suramin inhibiting the human basic fibroblast growth factor

scientific article published on July 1998

Synthesis and binding mode of heterocyclic analogues of suramin inhibiting the human basic fibroblast growth factor is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0968-0896(98)00052-2
P698PubMed publication ID9730230

P50authorFabrizio ManettiQ37605198
P2093author name stringBotta M
Mongelli N
Cappello V
Ciomei M
Corelli F
Borgia AL
Biasoli G
P2860cites workThree-dimensional structure of human basic fibroblast growth factor, a structural homolog of interleukin 1 betaQ24563285
Three-dimensional structure of human basic fibroblast growth factorQ24563295
Recent developments in the cell biology of basic fibroblast growth factorQ24679568
Crystal structure of basic fibroblast growth factor at 1.6 A resolutionQ27647318
Structural studies of the binding of the anti-ulcer drug sucrose octasulfate to acidic fibroblast growth factorQ27729397
Heparin structure and interactions with basic fibroblast growth factorQ27732601
Three-Dimensional Structures of Acidic and Basic Fibroblast Growth FactorsQ28267322
What Is the Evidence That Tumors Are Angiogenesis Dependent?Q29620029
Preferential self-association of basic fibroblast growth factor is stabilized by heparin during receptor dimerization and activation.Q33583925
Autocrine transformation by chimeric signal peptide-basic fibroblast growth factor: reversal by suraminQ33687824
Tumor angiogenesis and metastasis--correlation in invasive breast carcinomaQ34570747
Human tumor cells synthesize an endothelial cell growth factor that is structurally related to basic fibroblast growth factorQ35599351
Suramin prevents neovascularisation and tumour growth through blocking of basic fibroblast growth factor activityQ35994206
Growth factors and cancerQ36441643
FGF binding and FGF receptor activation by synthetic heparan-derived di- and trisaccharides.Q38296447
Differential effects of suramin on the coupling of receptors to individual species of pertussis-toxin-sensitive guanine-nucleotide-binding proteinsQ41951760
New sulfonated distamycin A derivatives with bFGF complexing activityQ42802546
Nature of the interaction of growth factors with suraminQ42816405
Suramin binds to platelet-derived growth factor and inhibits its biological activityQ42816663
Isolation of a tumor factor responsible for angiogenesisQ42835506
A priori prediction of activity for HIV-1 protease inhibitors employing energy minimization in the active site.Q52352855
Differential inhibition of various deoxyribonucleic and ribonucleic acid polymerases by suramin.Q54388450
An in vivo model for study of the angiogenic effects of basic fibroblast growth factorQ56428784
A family of angiogenic peptidesQ59071772
Theoretical quantitative structure—activity relationship analysis on three dimensional models of ligand—m1 muscarinic receptor complexesQ59614399
Synthesis of C-Alkyl Calix[4]arenes. 3. Acid-Catalyzed Rearrangement of 2,6-Dimethoxycinnamate Prior to Tetramerization to Calix[4]arenesQ62085876
A new class of steroids inhibits angiogenesis in the presence of heparin or a heparin fragmentQ68948783
Inhibition of vacuolar H+-ATPases by fusidic acid and suraminQ69920618
Energetic characterization of the basic fibroblast growth factor-heparin interaction: identification of the heparin binding domainQ72326632
Diltiazem-like calcium entry blockers: a hypothesis of the receptor-binding site based on a comparative molecular field analysis modelQ73030694
Isolation and characterization of angiogenin, an angiogenic protein from human carcinoma cellsQ93657789
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectsuraminQ425946
P304page(s)947-958
P577publication date1998-07-01
P1433published inBioorganic & Medicinal ChemistryQ2904200
P1476titleSynthesis and binding mode of heterocyclic analogues of suramin inhibiting the human basic fibroblast growth factor
P478volume6

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cites work (P2860)
Q30668040Identification of inhibitors of heparin-growth factor interactions from combinatorial libraries of four-component condensation reactions
Q34570156Molecular modeling as a powerful technique for understanding small-large molecules interactions.
Q35033986Nanoscale growth factor patterns by immobilization on a heparin-mimicking polymer
Q40206704Nature of Interaction between basic fibroblast growth factor and the antiangiogenic drug 7,7-(carbonyl-bis[imino-N-methyl-4,2-pyrrolecarbonylimino[N-methyl-4,2-pyrrole]-carbonylimino])-bis-(1,3-naphtalene disulfonate). II. Removal of polar interacti
Q30493655Non-peptidic thrombospondin-1 mimics as fibroblast growth factor-2 inhibitors: an integrated strategy for the development of new antiangiogenic compounds
Q35812264Protein recognition using synthetic surface-targeted agents
Q73803116Research on anti-HIV-1 agents. Investigation on the CD4-Suradista binding mode through docking experiments
Q46639843Structural basis for antagonism by suramin of heparin binding to vaccinia complement protein
Q34276825Synthesis of a heparan sulfate mimetic library targeting FGF and VEGF via click chemistry on a monosaccharide template

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