| scholarly article | Q13442814 |
| P819 | ADS bibcode | 1995PNAS...92.6414Z |
| P356 | DOI | 10.1073/PNAS.92.14.6414 |
| P932 | PMC publication ID | 41528 |
| P698 | PubMed publication ID | 7604005 |
| P5875 | ResearchGate publication ID | 15595147 |
| P50 | author | Stefano Stifani | Q37377205 |
| P2093 | author name string | S Stifani | |
| S Artavanis-Tsakonas | |||
| M L Carcangiu | |||
| C M Blaumueller | |||
| P Zagouras | |||
| P2860 | cites work | TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms | Q24320364 |
| Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins | Q24324093 | ||
| Chromosomal Deficiencies and the Embryonic Development of Drosophila Melanogaster | Q24521850 | ||
| Inactivation of the NF1 gene in human melanoma and neuroblastoma cell lines without impaired regulation of GTP.Ras | Q24562679 | ||
| Sequence of the notch locus of Drosophila melanogaster: relationship of the encoded protein to mammalian clotting and growth factors | Q24617135 | ||
| Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase | Q27860943 | ||
| Notch2: a second mammalian Notch gene | Q28568315 | ||
| Notch signaling | Q29618190 | ||
| Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development | Q30996868 | ||
| Complex cellular and subcellular regulation of notch expression during embryonic and imaginal development of Drosophila: implications for notch function | Q33531897 | ||
| Mouse mammary tumor gene int-3: a member of the notch gene family transforms mammary epithelial cells | Q33934024 | ||
| Nucleotide sequence from the neurogenic locus notch implies a gene product that shares homology with proteins containing EGF-like repeats | Q34195800 | ||
| An activated Notch suppresses neurogenesis and myogenesis but not gliogenesis in mammalian cells. | Q34325301 | ||
| Intrinsic activity of the Lin-12 and Notch intracellular domains in vivo | Q34352020 | ||
| Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei | Q34357811 | ||
| In vitro and in vivo analysis of cellular origin of cervical squamous metaplasia | Q35833252 | ||
| Mouse notch: expression in hair follicles correlates with cell fate determination | Q36232456 | ||
| Cloning and expression of antigenic epitopes of the human 68-kDa (U1) ribonucleoprotein antigen in Escherichia coli | Q42155608 | ||
| Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila | Q42811102 | ||
| Expression of an extracellular deletion of Xotch diverts cell fate in Xenopus embryos | Q46931754 | ||
| The intracellular domain of mouse Notch: a constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD. | Q51131644 | ||
| An activated Notch receptor blocks cell-fate commitment in the developing Drosophila eye. | Q51139583 | ||
| P433 | issue | 14 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 6414-6418 | |
| P577 | publication date | 1995-07-01 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Alterations in Notch signaling in neoplastic lesions of the human cervix | |
| P478 | volume | 92 |
| Q73958442 | A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1 |
| Q36187030 | ADAM proteases, ErbB pathways and cancer |
| Q97524272 | Aberrant promoter methylation of NOTCH1 and NOTCH3 and its association with cervical cancer risk factors in North Indian population |
| Q35020680 | Activated Notch1 inhibits p53-induced apoptosis and sustains transformation by human papillomavirus type 16 E6 and E7 oncogenes through a PI3K-PKB/Akt-dependent pathway |
| Q53582142 | Activated Notch1 interacts with p53 to inhibit its phosphorylation and transactivation. |
| Q74624551 | Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells |
| Q34084509 | Activation of Notch1 signaling is required for beta-catenin-mediated human primary melanoma progression |
| Q37371156 | Active Notch1 confers a transformed phenotype to primary human melanocytes |
| Q24529859 | Affinity for the nuclear compartment and expression during cell differentiation implicate phosphorylated Groucho/TLE1 forms of higher molecular mass in nuclear functions |
| Q33968716 | Analysis of dominant enhancers and suppressors of activated Notch in Drosophila |
| Q38713045 | Antagonism of EGFR and Notch limits resistance to EGFR inhibitors and radiation by decreasing tumor-initiating cell frequency. |
| Q33755151 | Arbiter of differentiation and death: Notch signaling meets apoptosis |
| Q33917356 | Beyond angiogenesis blockade: targeted therapy for advanced cervical cancer |
| Q24550771 | Binding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2 |
| Q22008610 | CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex |
| Q41970963 | Calcium binding to tandem repeats of EGF-like modules. Expression and characterization of the EGF-like modules of human Notch-1 implicated in receptor-ligand interactions |
| Q28609673 | Calcium depletion dissociates and activates heterodimeric notch receptors |
| Q28085552 | Cancer Genome Atlas Pan-cancer Analysis Project |
| Q88608530 | Canonical Notch Signaling Directs the Fate of Differentiating Neurocompetent Progenitors in the Mammalian Olfactory Epithelium |
| Q45085877 | Cell-surface Notch1 expression identifies a primitive phenotype within CD34+ CD38- haematopoietic cells |
| Q42040176 | Cellular senescence checkpoint function determines differential Notch1-dependent oncogenic and tumor-suppressor activities. |
| Q28580975 | Characterization of a high-molecular-weight Notch complex in the nucleus of Notch(ic)-transformed RKE cells and in a human T-cell leukemia cell line |
| Q31121505 | Characterization of gene expression in mucinous cystic neoplasms of the pancreas using oligonucleotide microarrays |
| Q38375349 | Clinical Activity of the γ-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors (Aggressive Fibromatosis). |
| Q38605837 | Clinicopathological significance of Notch1 expression in cervical cancer patients: a meta-analysis |
| Q40209531 | Coexpression of Notch1 and NF-kappaB signaling pathway components in human cervical cancer progression |
| Q28212477 | Common fragile sites are preferential targets for HPV16 integrations in cervical tumors |
| Q33843034 | Complementation of human papillomavirus type 16 E6 and E7 by Jagged1-specific Notch1-phosphatidylinositol 3-kinase signaling involves pleiotropic oncogenic functions independent of CBF1;Su(H);Lag-1 activation. |
| Q36772826 | Conservation of the Drosophila lateral inhibition pathway in human lung cancer: a hairy-related protein (HES-1) directly represses achaete-scute homolog-1 expression |
| Q33601436 | Cooperation of Notch and Ras/MAPK signaling pathways in human breast carcinogenesis |
| Q53282153 | Cooperation of deregulated Notch signaling and Ras pathway in human hepatocarcinogenesis. |
| Q84242761 | Crosstalk of Notch with p53 and p63 in cancer growth control |
| Q30419809 | Cutaneous papillomavirus E6 oncoproteins associate with MAML1 to repress transactivation and NOTCH signaling |
| Q37073031 | Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein |
| Q47558699 | Dicer1, AGO3, and AGO4 microRNA machinery genes are differentially expressed in developing female reproductive organs and overexpressed in cancerous ovaries of chickens. |
| Q47854966 | Differential expression of Notch family members in astrocytomas and medulloblastomas |
| Q33966054 | Distinct expression profiles of Notch-1 protein in human solid tumors: Implications for development of targeted therapeutic monoclonal antibodies |
| Q36918095 | Drosophila Brat and Human Ortholog TRIM3 Maintain Stem Cell Equilibrium and Suppress Brain Tumorigenesis by Attenuating Notch Nuclear Transport |
| Q92651166 | Effects of Notch Signaling Pathway in Cervical Cancer by Curcumin Mediated Photodynamic Therapy and Its Possible Mechanisms in Vitro and in Vivo |
| Q36266177 | Endosomal sorting of Notch receptors through COMMD9-dependent pathways modulates Notch signaling |
| Q24678677 | Epstein-Barr virus immortalization: Notch2 interacts with CBF1 and blocks differentiation |
| Q33787090 | Epstein-barr virus nuclear antigen 3C activates the latent membrane protein 1 promoter in the presence of Epstein-Barr virus nuclear antigen 2 through sequences encompassing an spi-1/Spi-B binding site |
| Q36664205 | ErbB2 induces Notch1 activity and function in breast cancer cells |
| Q33229068 | Evidence for differential expression of Notch receptors and their ligands in melanocytic nevi and cutaneous malignant melanoma |
| Q36366728 | Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles |
| Q53176366 | Expression and oncogenic properties of membranous Notch1 in oral leukoplakia and oral squamous cell carcinoma. |
| Q37719966 | Expression of TSG101 protein and LSF transcription factor in HPV-positive cervical cancer cells |
| Q51561296 | Expression of activated Notch1 and Hey1 in papillary thyroid carcinoma. |
| Q34307427 | Expression of notch receptors and ligands in the adult gut. |
| Q24338190 | Follicular stimulating hormone enhances Notch 1 expression in SK-OV-3 ovarian cancer cells |
| Q27004534 | From fly wings to targeted cancer therapies: a centennial for notch signaling |
| Q40625650 | Functional and molecular characterization of the epithelioid to round transition in human colorectal cancer LoVo cells. |
| Q28203706 | Functional interaction between SEL-10, an F-box protein, and the nuclear form of activated Notch1 receptor |
| Q46531701 | Gamma secretase inhibitor blocks Notch activation and induces apoptosis in Kaposi's sarcoma tumor cells |
| Q37053722 | Gamma secretase inhibitors of Notch signaling |
| Q56889497 | Glycogene expression profiles based on microarray data from cervical carcinoma HeLa cells with partially silenced E6 and E7 HPV oncogenes |
| Q22009037 | Human ligands of the Notch receptor |
| Q36787632 | Human papilloma virus-dependent HMGA1 expression is a relevant step in cervical carcinogenesis |
| Q35248947 | Human papillomavirus 16E6 and NFX1-123 potentiate Notch signaling and differentiation without activating cellular arrest |
| Q34150408 | Human papillomavirus type 16 E6 amino acid 83 variants enhance E6-mediated MAPK signaling and differentially regulate tumorigenesis by notch signaling and oncogenic Ras. |
| Q24642237 | Identification of Notch-1 expression in the limbal basal epithelium |
| Q34492720 | Identification of a neural stem cell in the adult mammalian central nervous system |
| Q32151473 | Identification of a protein isolated from senescent human cells that binds to hepatitis B virus X antigen |
| Q53276039 | Identification of differential expressed transcripts in cervical cancer of Mexican patients. |
| Q35963866 | Immunohistochemical localization of Notch signaling molecules in ameloblastomas |
| Q33969345 | Induction of cyclin D1 transcription and CDK2 activity by Notch(ic): implication for cell cycle disruption in transformation by Notch(ic). |
| Q38048861 | Instigation of Notch signaling in the pathogenesis of Kaposi's sarcoma-associated herpesvirus and other human tumor viruses |
| Q34794711 | Integrated genomic and transcriptional profiling identifies chromosomal loci with altered gene expression in cervical cancer |
| Q38881352 | Interference of Notch1 inhibits the growth of glioma cancer cells by inducing cell autophagy and down-regulation of Notch1-Hes-1 signaling pathway |
| Q47159829 | Interplay between Notch1 and Notch3 promotes EMT and tumor initiation in squamous cell carcinoma. |
| Q24321237 | Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane |
| Q39751057 | Involvement of epigenetically silenced microRNA-181c in gastric carcinogenesis |
| Q24795290 | Is there a role for Notch signalling in human breast cancer? |
| Q37158989 | Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer |
| Q24290449 | Jagged2 induces cell cycling in confluent fibroblasts susceptible to density-dependent inhibition of cell division |
| Q28646378 | Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis |
| Q35178083 | Late SV40 factor: a key mediator of Notch signaling in human hepatocarcinogenesis |
| Q41814862 | Localization of putative stem cells in dental epithelium and their association with Notch and FGF signaling. |
| Q55176761 | Loss of nuclear NOTCH1, but not its negative regulator NUMB, is an independent predictor of cervical malignancy. |
| Q39530978 | MAML1 regulates cell viability via the NF-κB pathway in cervical cancer cell lines |
| Q21245465 | Main roads to melanoma |
| Q64990535 | Manipulation of Epithelial Differentiation by HPV Oncoproteins. |
| Q92969193 | Melanoma Progression Inhibits Pluripotency and Differentiation of Melanoma-Derived iPSCs Produces Cells with Neural-like Mixed Dysplastic Phenotype |
| Q34551486 | MicroRNA expression profiling and Notch1 and Notch2 expression in minimal deviation adenocarcinoma of uterine cervix |
| Q38637987 | MicroRNA-34a suppresses colorectal cancer metastasis by regulating Notch signaling |
| Q38245726 | Modeling cutaneous squamous carcinoma development in the mouse |
| Q35103047 | Modulation of notch signaling elicits signature tumors and inhibits hras1-induced oncogenesis in the mouse mammary epithelium |
| Q80094109 | Molecular cytogenetic characterization of t(14;19)(q32;p13), a new recurrent translocation in B cell malignancies |
| Q44691496 | Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development. |
| Q28146235 | Mouse jagged1 physically interacts with notch2 and other notch receptors. Assessment by quantitative methods |
| Q39631069 | NF-kappaB2 is a putative target gene of activated Notch-1 via RBP-Jkappa |
| Q37336719 | NFX1-123 and human papillomavirus 16E6 increase Notch expression in keratinocytes |
| Q33883897 | NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts |
| Q88344746 | NOTCH signalinio kelio ir ginekologinių piktybinių navikų sąsaja |
| Q39453336 | Neoplastic transformation by Notch requires nuclear localization |
| Q36573355 | Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2. |
| Q64989435 | Non-contact co-culture with human vascular endothelial cells promotes epithelial-to-mesenchymal transition of cervical cancer SiHa cells by activating the NOTCH1/LOX/SNAIL pathway. |
| Q36448329 | Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia |
| Q37671175 | Notch 1 signaling is active in ovarian cancer. |
| Q37133625 | Notch Signaling Activation in Cervical Cancer Cells Induces Cell Growth Arrest with the Involvement of the Nuclear Receptor NR4A2. |
| Q37802720 | Notch Signaling Pathway as a Therapeutic Target in Breast Cancer |
| Q26752380 | Notch Signaling in Neuroendocrine Tumors |
| Q38526539 | Notch activation is associated with tetraploidy and enhanced chromosomal instability in meningiomas |
| Q42804897 | Notch activation suppresses fibroblast growth factor-dependent cellular transformation |
| Q28586202 | Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine |
| Q33812251 | Notch and the immune system. |
| Q41601034 | Notch in vertebrates |
| Q39631179 | Notch inhibition of E47 supports the existence of a novel signaling pathway |
| Q34330869 | Notch inhibitors for cancer treatment |
| Q33598695 | Notch is a critical regulator in cervical cancer by regulating Numb splicing |
| Q50197788 | Notch signaling and non-small cell lung cancer |
| Q34754675 | Notch signaling as a therapeutic target |
| Q35551147 | Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents |
| Q34316148 | Notch signaling in mammary gland tumorigenesis |
| Q34982347 | Notch signaling proteins: legitimate targets for cancer therapy |
| Q37169972 | Notch signaling: targeting cancer stem cells and epithelial-to-mesenchymal transition |
| Q37256446 | Notch tumor suppressor function |
| Q40860023 | Notch(ic)-ER chimeras display hormone-dependent transformation, nuclear accumulation, phosphorylation and CBF1 activation. |
| Q28616666 | Notch-1 and Notch-2 exhibit unique patterns of expression in human B-lineage cells |
| Q39971503 | Notch-1 associates with IKKalpha and regulates IKK activity in cervical cancer cells. |
| Q77397546 | Notch-1 inhibits apoptosis in murine erythroleukemia cells and is necessary for differentiation induced by hybrid polar compounds |
| Q34686900 | Notch-EGFR/HER2 Bidirectional Crosstalk in Breast Cancer |
| Q53182267 | Notch1 expression correlates with tumor differentiation status in ovarian carcinoma. |
| Q29614987 | Notch1 functions as a tumor suppressor in mouse skin |
| Q48125597 | Notch1 inhibits neurite outgrowth in postmitotic primary neurons |
| Q41115136 | Notch1 ligand signaling pathway activated in cervical cancer: poor prognosis with high-level JAG1/Notch1. |
| Q41233759 | Notch1 regulates the JNK signaling pathway and increases apoptosis in hepatocellular carcinoma |
| Q29542551 | Notch1 regulates the functional contribution of RhoC to cervical carcinoma progression |
| Q39674715 | Notch1 regulates the growth of human colon cancers |
| Q35776244 | Notch1-mediated tumor suppression in cervical cancer with the involvement of SST signaling and its application in enhanced SSTR-targeted therapeutics |
| Q24292753 | Notch2 protein distribution in human teeth under normal and pathological conditions |
| Q36529184 | Notch2 regulates matrix metallopeptidase 9 via PI3K/AKT signaling in human gastric carcinoma cell MKN-45 |
| Q53851403 | Notch4 intracellular domain binding to Smad3 and inhibition of the TGF-beta signaling. |
| Q77965808 | Ovarian and breast cytotoxic T lymphocytes can recognize peptides from the amino enhancer of split protein of the Notch complex |
| Q35758978 | Overexpression of Notch1 is associated with the progression of cervical cancer |
| Q24563952 | Papillomavirus-mediated neoplastic progression is associated with reciprocal changes in JAGGED1 and manic fringe expression linked to notch activation |
| Q36317946 | Paradigms of notch signaling in mammals. |
| Q28286560 | Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J kappa/Su(H) |
| Q36165373 | PlexinD1 Is a Novel Transcriptional Target and Effector of Notch Signaling in Cancer Cells |
| Q39626163 | Portrayal of the Notch system in embryonic stem cell-derived embryoid bodies |
| Q39397203 | Reduction of NOTCH1 expression pertains to maturation abnormalities of keratinocytes in squamous neoplasms |
| Q35856917 | Regulation of Notch1 gene expression by p53 in epithelial cells |
| Q90390362 | Regulation of the Notch-ATM-abl axis by geranylgeranyl diphosphate synthase inhibition |
| Q60921423 | Relationship between the upregulation of Notch1 signaling and the clinical characteristics of patients with papillary thyroid carcinoma in East Asia: a systematic review and meta-analysis |
| Q40764510 | Repression of activator protein-1-mediated transcriptional activation by the Notch-1 intracellular domain |
| Q21195157 | Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells |
| Q37908176 | Role of Notch signaling in colon homeostasis and carcinogenesis |
| Q37606133 | Role of Notch signaling in colorectal cancer |
| Q24555052 | Siah-1 binds and regulates the function of Numb |
| Q37724159 | Signal transduction by activated mNotch: importance of proteolytic processing and its regulation by the extracellular domain. |
| Q38370778 | Signaling pathways in HPV-associated cancers and therapeutic implications. |
| Q35995318 | Silencing Notch-1 induces apoptosis and increases the chemosensitivity of prostate cancer cells to docetaxel through Bcl-2 and Bax. |
| Q36855712 | Soluble forms of the Notch ligands Delta1 and Jagged1 promote in vivo tumorigenicity in NIH3T3 fibroblasts with distinct phenotypes |
| Q35787104 | Specific down-modulation of Notch1 signaling in cervical cancer cells is required for sustained HPV-E6/E7 expression and late steps of malignant transformation |
| Q33901073 | Stimulation of human epidermal differentiation by delta-notch signalling at the boundaries of stem-cell clusters. |
| Q24524755 | Structure and coding content of CST (BART) family RNAs of Epstein-Barr virus |
| Q40023443 | Synergy between suppressor of Hairless and Notch in regulation of Enhancer of split m gamma and m delta expression |
| Q24678251 | T cell leukemia-associated human Notch/translocation-associated Notch homologue has I kappa B-like activity and physically interacts with nuclear factor-kappa B proteins in T cells |
| Q37286140 | TLE3 represses colorectal cancer proliferation by inhibiting MAPK and AKT signaling pathways |
| Q36020893 | Targeting Notch1 and proteasome as an effective strategy to suppress T-cell lymphoproliferative neoplasms |
| Q37696748 | Targeting notch signaling pathway in cancer: clinical development advances and challenges |
| Q38359402 | The C-terminal PDZ-ligand of JAGGED1 is essential for cellular transformation |
| Q24606808 | The Cancer Genome Atlas Pan-Cancer analysis project |
| Q47645064 | The Hajdu Cheney Mutation Is a Determinant of B-Cell Allocation of the Splenic Marginal Zone |
| Q36615348 | The Notch pathway in ovarian carcinomas and adenomas. |
| Q54628566 | The Notch signaling pathway is related to neurovascular progression of pancreatic cancer. |
| Q26767061 | The Role of HPV in Head and Neck Cancer Stem Cell Formation and Tumorigenesis |
| Q46066754 | The effect of LRAP on enamel organ epithelial cell differentiation |
| Q83310074 | The functional role of Notch signaling in HPV-mediated transformation is dose-dependent and linked to AP-1 alterations |
| Q35920751 | The intracellular form of notch blocks transforming growth factor beta-mediated growth arrest in Mv1Lu epithelial cells |
| Q39656326 | The lymphovascular embolus of inflammatory breast cancer exhibits a Notch 3 addiction |
| Q34012680 | The notch intracellular domain can function as a coactivator for LEF-1 |
| Q21129294 | The notch ligand JAGGED1 as a target for anti-tumor therapy |
| Q35564593 | The role of Notch in tumorigenesis: oncogene or tumour suppressor? |
| Q37256444 | The role of Notch signaling in human cervical cancer: implications for solid tumors |
| Q28482805 | Therapeutic efficacy by targeting correction of Notch1-induced aberrants in uveal tumors |
| Q24650743 | Truncated mammalian Notch1 activates CBF1/RBPJk-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2 |
| Q33963617 | Two distinct Notch1 mutant alleles are involved in the induction of T-cell leukemia in c-myc transgenic mice |
| Q35141769 | Vasculogenic mimicry and tumour-cell plasticity: lessons from melanoma |
| Q40336111 | c-Myc substitutes for Notch1-CBF1 functions in cooperative transformation with papillomavirus oncogenes |
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