| P50 | author | Freddy Radtke | Q41621239 |
| P2093 | author name string | Kenneth Raj | |
| P2860 | cites work | p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities | Q22003973 |
| | CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex | Q22008610 |
| | SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC function | Q22253329 |
| | Differential effects of Notch ligands Delta-1 and Jagged-1 in human lymphoid differentiation | Q24291744 |
| | Notch signaling induces rapid degradation of achaete-scute homolog 1. | Q24293622 |
| | Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-kappaB and PPARgamma | Q24301127 |
| | TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms | Q24320364 |
| | Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane | Q24321237 |
| | Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a | Q24324559 |
| | Notch signalling is linked to epidermal cell differentiation level in basal cell carcinoma, psoriasis and wound healing | Q24524157 |
| | p300 acts as a transcriptional coactivator for mammalian Notch-1 | Q24548267 |
| | A histone deacetylase corepressor complex regulates the Notch signal transduction pathway | Q24598533 |
| | An activated form of Notch influences the choice between CD4 and CD8 T cell lineages | Q46109980 |
| | Shaggy/GSK3 antagonizes Hedgehog signalling by regulating Cubitus interruptus | Q47070663 |
| | Proteolysis of the Hedgehog signaling effector Cubitus interruptus requires phosphorylation by Glycogen Synthase Kinase 3 and Casein Kinase 1. | Q47071799 |
| | Cloning, analysis, and chromosomal localization of Notch-1, a mouse homolog of Drosophila Notch | Q48134294 |
| | Motch A and motch B--two mouse Notch homologues coexpressed in a wide variety of tissues | Q48134478 |
| | Analysis of DNA surrounding the breakpoints of chromosomal translocations involving the beta T cell receptor gene in human lymphoblastic neoplasms | Q48341925 |
| | Association of SV40 with human tumors | Q48684971 |
| | Interaction between Wingless and Notch signaling pathways mediated by dishevelled. | Q50319776 |
| | Notch1 expression in early lymphopoiesis influences B versus T lineage determination. | Q51085324 |
| | Notch signalling and the control of cell fate choices in vertebrates. | Q52180338 |
| | Modulators of Notch signaling. | Q52567848 |
| | The Theory of the Gene | Q56456417 |
| | Frequent provirus insertional mutagenesis of Notch1 in thymomas of MMTVD/myc transgenic mice suggests a collaboration of c-myc and Notch1 for oncogenesis | Q59285746 |
| | Maintenance of neuroepithelial progenitor cells by Delta–Notch signalling in the embryonic chick retina | Q60492575 |
| | Neoplastic transformation by Notch is independent of transcriptional activation by RBP-J signalling | Q64380924 |
| | Ras pathway signals are required for notch-mediated oncogenesis | Q74298005 |
| | DeltaNp63 induces beta-catenin nuclear accumulation and signaling | Q74372626 |
| | Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells | Q74624551 |
| | Tumor suppression by p27Kip1 and p21Cip1 during chemically induced skin carcinogenesis | Q78192926 |
| | Sequence of the notch locus of Drosophila melanogaster: relationship of the encoded protein to mammalian clotting and growth factors | Q24617135 |
| | The Notch1 receptor is cleaved constitutively by a furin-like convertase | Q24671866 |
| | Disruption of epithelial cell-matrix interactions induces apoptosis | Q24673611 |
| | Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex | Q24675233 |
| | Involvement of Notch1 in the development of mouse mammary tumors | Q28137765 |
| | PIK3CA as an oncogene in cervical cancer | Q28138126 |
| | Functional interaction between the mouse notch1 intracellular region and histone acetyltransferases PCAF and GCN5 | Q28140561 |
| | Creation of human tumour cells with defined genetic elements | Q28141602 |
| | An achaete-scute homologue essential for neuroendocrine differentiation in the lung | Q28236555 |
| | Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes | Q28265486 |
| | Neurogenic genes and vertebrate neurogenesis | Q28288990 |
| | Jagged: A mammalian ligand that activates notch1 | Q28298760 |
| | Targeted disruption of mammalian hairy and Enhancer of split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects | Q28507755 |
| | Jagged2: a serrate-like gene expressed during rat embryogenesis | Q28580835 |
| | The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium | Q28623130 |
| | The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53 | Q29547773 |
| | Induction of apoptosis in fibroblasts by c-myc protein | Q29614346 |
| | Notch1 functions as a tumor suppressor in mouse skin | Q29614987 |
| | Human papillomavirus is a necessary cause of invasive cervical cancer worldwide | Q29617514 |
| | Notch signaling | Q29618190 |
| | The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product | Q29618372 |
| | Continued expression of HPV-16 E7 protein is required for maintenance of the transformed phenotype of cells co-transformed by HPV-16 plus EJ-ras. | Q33559590 |
| | Gain of chromosome 3q defines the transition from severe dysplasia to invasive carcinoma of the uterine cervix | Q33632013 |
| | Comparative genomic hybridization and chromosomal instability in solid tumours | Q33653215 |
| | Fringe, Notch, and making developmental boundaries. | Q33712532 |
| | Identification of a novel NOTCH-4/INT-3 RNA species encoding an activated gene product in certain human tumor cell lines | Q33887486 |
| | Stimulation of human epidermal differentiation by delta-notch signalling at the boundaries of stem-cell clusters. | Q33901073 |
| | Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by notch1. | Q33965862 |
| | Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation | Q34077697 |
| | A novel Notch ligand, Dll4, induces T-cell leukemia/lymphoma when overexpressed in mice by retroviral-mediated gene transfer | Q34104543 |
| | Deltex1 redirects lymphoid progenitors to the B cell lineage by antagonizing Notch1. | Q34116313 |
| | Alterations in Notch signaling in neoplastic lesions of the human cervix | Q34124673 |
| | Nucleotide sequence from the neurogenic locus notch implies a gene product that shares homology with proteins containing EGF-like repeats | Q34195800 |
| | Inactivation of both the retinoblastoma tumor suppressor and p21 by the human papillomavirus type 16 E7 oncoprotein is necessary to inhibit cell cycle arrest in human epithelial cells | Q34348705 |
| | Biology of HER2 and its importance in breast cancer | Q34428745 |
| | Expression of beta-catenin, a key mediator of the WNT signaling pathway, in basal cell carcinoma | Q42490438 |
| | Expression of the p53 homologue p63 in early cervical neoplasia | Q42497885 |
| | Histologic and immunophenotypic classification of cervical carcinomas by expression of the p53 homologue p63: a study of 250 cases | Q42505085 |
| | Immunohistochemical detection for nuclear beta-catenin in sporadic basal cell carcinoma | Q42513852 |
| | Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway | Q42618265 |
| | Transcriptional repression by suppressor of hairless involves the binding of a hairless-dCtBP complex in Drosophila. | Q43621582 |
| | Expression of an activated Notch-related int-3 transgene interferes with cell differentiation and induces neoplastic transformation in mammary and salivary glands | Q45182928 |
| | Deficient T cell fate specification in mice with an induced inactivation of Notch1. | Q45345200 |
| | Suppressor of hairless directly activates transcription of enhancer of split complex genes in response to Notch receptor activity | Q45950823 |
| | Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila neurogenic gene Delta | Q46026585 |
| | Biological activities and molecular targets of the human papillomavirus E7 oncoprotein | Q34468787 |
| | An overview of HER2. | Q34482977 |
| | Vertebrate hairy and Enhancer of split related proteins: transcriptional repressors regulating cellular differentiation and embryonic patterning | Q34526571 |
| | Gli and hedgehog in cancer: tumours, embryos and stem cells. | Q34665999 |
| | CSL-independent Notch signalling: a checkpoint in cell fate decisions during development? | Q34801905 |
| | Growth suppression of pre-T acute lymphoblastic leukemia cells by inhibition of notch signaling | Q34811698 |
| | Modulation of receptor signaling by glycosylation: fringe is an O-fucose-beta1,3-N-acetylglucosaminyltransferase | Q34989571 |
| | Similarities between the Hedgehog and Wnt signaling pathways | Q35006446 |
| | ErbBs in mammary development | Q35089320 |
| | NF-kappaB in cancer: a marked target | Q35091120 |
| | Notch signaling in lymphopoiesis. | Q35101882 |
| | Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice | Q35114942 |
| | p21(WAF1/Cip1) functions as a suppressor of malignant skin tumor formation and a determinant of keratinocyte stem-cell potential | Q35595760 |
| | Specific down-modulation of Notch1 signaling in cervical cancer cells is required for sustained HPV-E6/E7 expression and late steps of malignant transformation | Q35787104 |
| | Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles | Q36366728 |
| | Separation of Notch1 promoted lineage commitment and expansion/transformation in developing T cells | Q36369337 |
| | Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2. | Q36573355 |
| | Inhibition of granulocytic differentiation by mNotch1. | Q36686889 |
| | The link between integration and expression of human papillomavirus type 16 genomes and cellular changes in the evolution of cervical intraepithelial neoplastic lesions | Q36861078 |
| | AIS is an oncogene amplified in squamous cell carcinoma | Q36978000 |
| | Notch1 signaling promotes the maturation of CD4 and CD8 SP thymocytes | Q37428286 |
| | Perturbation of Ikaros isoform selection by MLV integration is a cooperative event in Notch(IC)-induced T cell leukemogenesis | Q38352939 |
| | Neoplastic transformation by Notch requires nuclear localization | Q39453336 |
| | NF-kappaB2 is a putative target gene of activated Notch-1 via RBP-Jkappa | Q39631069 |
| | The ras gene family and human carcinogenesis | Q39638098 |
| | E7 abolishes raf-induced arrest via mislocalization of p21(Cip1). | Q39695591 |
| | p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas | Q39742724 |
| | Simian Virus 40 Infection of Humans | Q39748728 |
| | The E6-E7 region of human papillomavirus type 18 is sufficient for transformation of NIH 3T3 and rat-1 cells | Q40141212 |
| | Notch-1 induction, a novel activity of SV40 required for growth of SV40-transformed human mesothelial cells | Q40677575 |
| | Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro. | Q40683787 |
| | Phosphatidylinositol 3-kinase/Akt stimulates androgen pathway through GSK3beta inhibition and nuclear beta-catenin accumulation | Q40725486 |
| | Repression of activator protein-1-mediated transcriptional activation by the Notch-1 intracellular domain | Q40764510 |
| | Activated Notch1 signaling cooperates with papillomavirus oncogenes in transformation and generates resistance to apoptosis on matrix withdrawal through PKB/Akt | Q40793293 |
| | Notch(ic)-ER chimeras display hormone-dependent transformation, nuclear accumulation, phosphorylation and CBF1 activation. | Q40860023 |
| | Transient Notch activation initiates an irreversible switch from neurogenesis to gliogenesis by neural crest stem cells | Q40874695 |
| | Telomerase activation by the E6 gene product of human papillomavirus type 16. | Q41218028 |
| | The LIN-12/Notch signaling pathway and its regulation | Q41689370 |
| | Regulation of the ERBB-2 promoter by RBPJkappa and NOTCH. | Q42438785 |
| P433 | issue | 10 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 756-767 | |
| P577 | publication date | 2003-10-01 | |
| P1433 | published in | Nature Reviews Cancer | Q641657 |
| P1476 | title | The role of Notch in tumorigenesis: oncogene or tumour suppressor? | |
| P478 | volume | 3 | |