| scholarly article | Q13442814 |
| P50 | author | Phillips Y Huang | Q46194914 |
| P2093 | author name string | Allan Balmain | |
| P2860 | cites work | Direct control of the Forkhead transcription factor AFX by protein kinase B | Q22009452 |
| Hallmarks of Cancer: The Next Generation | Q22252312 | ||
| Small G protein Ral and its downstream molecules regulate endocytosis of EGF and insulin receptors | Q24534185 | ||
| Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer | Q24605866 | ||
| Cancer-related inflammation | Q27860907 | ||
| PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer | Q27860985 | ||
| A cell initiating human acute myeloid leukaemia after transplantation into SCID mice | Q28131777 | ||
| Regulation of cutaneous malignancy by gammadelta T cells | Q28188439 | ||
| Cancer stem cells: mirage or reality? | Q28257690 | ||
| Comprehensive genomic characterization of squamous cell lung cancers | Q28274701 | ||
| RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesis | Q28294501 | ||
| Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers | Q28306997 | ||
| Deficiency of either cyclooxygenase (COX)-1 or COX-2 alters epidermal differentiation and reduces mouse skin tumorigenesis | Q28593718 | ||
| An Essential Role for Rho, Rac, and Cdc42 GTPases in Cell Cycle Progression Through G 1 | Q29614256 | ||
| Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1 | Q29614651 | ||
| The mutational landscape of head and neck squamous cell carcinoma | Q29614654 | ||
| Notch1 functions as a tumor suppressor in mouse skin | Q29614987 | ||
| Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome | Q29615538 | ||
| A restricted cell population propagates glioblastoma growth after chemotherapy | Q29615605 | ||
| Rac1 is crucial for hair follicle integrity but is not essential for maintenance of the epidermis | Q30478066 | ||
| Mutations in cancer genes of UV-induced skin tumors of hairless mice | Q30844910 | ||
| Transgenic mice expressing a mutant keratin 10 gene reveal the likely genetic basis for epidermolytic hyperkeratosis | Q30990411 | ||
| Mechanism-based cancer prevention approaches: targets, examples, and the use of transgenic mice. | Q33536327 | ||
| Stochastic fate of p53-mutant epidermal progenitor cells is tilted toward proliferation by UV B during preneoplasia | Q33591760 | ||
| Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs | Q33609142 | ||
| Early p53 alterations in mouse skin carcinogenesis by UVB radiation: immunohistochemical detection of mutant p53 protein in clusters of preneoplastic epidermal cells | Q33616030 | ||
| Inflammatory skin disease in transgenic mice that express high levels of interleukin 1 alpha in basal epidermis | Q33730207 | ||
| Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice | Q33840379 | ||
| Overview of carcinogenesis: past, present and future | Q33846161 | ||
| p53-mediated hematopoietic stem and progenitor cell competition. | Q33857597 | ||
| Inducible cutaneous inflammation reveals a protumorigenic role for keratinocyte CXCR2 in skin carcinogenesis | Q33858156 | ||
| A single type of progenitor cell maintains normal epidermis | Q53568370 | ||
| Activator protein-1 activity regulates epithelial tumor cell identity | Q53591496 | ||
| The effect of aging and interval between primary and secondary treatment in two-stage carcinogenesis on mouse skin | Q53595643 | ||
| p53 suppresses the self-renewal of adult neural stem cells | Q53643375 | ||
| Metastasis is driven by sequential elevation of H-ras and Smad2 levels | Q54297451 | ||
| Skin hyperkeratosis and papilloma formation in transgenic mice expressing a ras oncogene from a suprabasal keratin promoter | Q57086717 | ||
| Acute upregulation of an NKG2D ligand promotes rapid reorganization of a local immune compartment with pleiotropic effects on carcinogenesis | Q60241749 | ||
| Effects of antiinflammatory agents on mouse skin tumor promotion, epidermal DNA synthesis, phorbol ester-induced cellular proliferation, and production of plasminogen activator | Q67567855 | ||
| Multistage chemical carcinogenesis protocols produce spindle cell carcinomas of the mouse skin | Q69108506 | ||
| Sequential trisomization of chromosomes 6 and 7 in mouse skin premalignant lesions | Q69204494 | ||
| On the persistence of tumor initiation in two-stage carcinogenesis on mouse skin | Q70437057 | ||
| Prevention and early detection strategies for melanoma and skin cancer. Current status | Q71077363 | ||
| Human epidermal cancer and accompanying precursors have identical p53 mutations different from p53 mutations in adjacent areas of clonally expanded non-neoplastic keratinocytes | Q71084069 | ||
| Targeted overexpression of transforming growth factor alpha in the epidermis of transgenic mice elicits hyperplasia, hyperkeratosis, and spontaneous, squamous papillomas | Q72266384 | ||
| Frequent p53 alterations but low incidence of ras mutations in UV-B-induced skin tumors of hairless mice | Q72280974 | ||
| FVB/N mice: an inbred strain sensitive to the chemical induction of squamous cell carcinomas in the skin | Q72613784 | ||
| Evidence that the epidermal targets of carcinogen action are found in the interfollicular epidermis of infundibulum as well as in the hair follicles | Q73430496 | ||
| The malignant capacity of skin tumours induced by expression of a mutant H-ras transgene depends on the cell type targeted | Q74481870 | ||
| The exocyst is a Ral effector complex | Q77342588 | ||
| Keratinocyte-specific Pten deficiency results in epidermal hyperplasia, accelerated hair follicle morphogenesis and tumor formation | Q78881939 | ||
| Low incidence of EGFR and HRAS mutations in cutaneous squamous cell carcinomas of a German cohort | Q84575433 | ||
| Loss of cutaneous TSLP-dependent immune responses skews the balance of inflammation from tumor protective to tumor promoting | Q85225717 | ||
| AP1 factor inactivation in the suprabasal epidermis causes increased epidermal hyperproliferation and hyperkeratosis but reduced carcinogen-dependent tumor formation | Q42201057 | ||
| c-Jun regulates eyelid closure and skin tumor development through EGFR signaling | Q42442584 | ||
| The interfollicular epidermis of adult mouse tail comprises two distinct cell lineages that are differentially regulated by Wnt, Edaradd, and Lrig1. | Q42445148 | ||
| Expression of activated MEK1 in differentiating epidermal cells is sufficient to generate hyperproliferative and inflammatory skin lesions | Q42465996 | ||
| The effect of c-myc on stem cell fate influences skin tumor phenotype | Q42467107 | ||
| Identification of the cell lineage at the origin of basal cell carcinoma | Q42467302 | ||
| Evidence for discrete cell kinetic subpopulations in mouse epidermis based on mathematical analysis | Q42468280 | ||
| Crucial role of phospholipase Cepsilon in chemical carcinogen-induced skin tumor development | Q42471916 | ||
| Probing Keratinocyte and Differentiation Specificity of the Human K5 Promoter in Vitro and in Transgenic Mice | Q42483235 | ||
| Transgenic mice overexpressing protein kinase C epsilon in their epidermis exhibit reduced papilloma burden but enhanced carcinoma formation after tumor promotion | Q42483668 | ||
| The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development | Q42492007 | ||
| Impaired notch signaling promotes de novo squamous cell carcinoma formation | Q42499149 | ||
| Deregulated expression of c-Myc depletes epidermal stem cells | Q42505079 | ||
| Deregulated activity of Akt in epithelial basal cells induces spontaneous tumors and heightened sensitivity to skin carcinogenesis | Q42521538 | ||
| The epidermis comprises autonomous compartments maintained by distinct stem cell populations | Q42659111 | ||
| Skin squamous cell carcinoma propagating cells increase with tumour progression and invasiveness. | Q42733062 | ||
| Progression of squamous carcinoma cells to spindle carcinomas of mouse skin is associated with an imbalance of H-ras alleles on chromosome 7 | Q42808827 | ||
| Mouse skin carcinomas induced in vivo by chemical carcinogens have a transforming Harvey-ras oncogene | Q42823403 | ||
| Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1. | Q42827718 | ||
| Rac1 is crucial for Ras-dependent skin tumor formation by controlling Pak1-Mek-Erk hyperactivation and hyperproliferation in vivo | Q43103589 | ||
| Selective role for Mek1 but not Mek2 in the induction of epidermal neoplasia. | Q43244288 | ||
| Application of phorbol ester to mouse skin causes a rapid and sustained loss of protein kinase C. | Q43434571 | ||
| Suppression of skin tumorigenesis in c-Jun NH(2)-terminal kinase-2-deficient mice. | Q43612255 | ||
| Myc lacks E2F1's ability to suppress skin carcinogenesis | Q43728206 | ||
| Deficiency of c-Jun-NH(2)-terminal kinase-1 in mice enhances skin tumor development by 12-O-tetradecanoylphorbol-13-acetate. | Q43913532 | ||
| Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours. | Q44035580 | ||
| Disruption of protein kinase Ceta results in impairment of wound healing and enhancement of tumor formation in mouse skin carcinogenesis. | Q44443207 | ||
| IL-1 alpha, innate immunity, and skin carcinogenesis: the effect of constitutive expression of IL-1 alpha in epidermis on chemical carcinogenesis | Q44448918 | ||
| Raf-1 addiction in Ras-induced skin carcinogenesis | Q44785829 | ||
| Epidermal growth factor receptor-mediated activation of Stat3 during multistage skin carcinogenesis | Q44826931 | ||
| Differential down-regulation of epidermal protein kinase C by 12-O-tetradecanoylphorbol-13-acetate and diacylglycerol: association with epidermal hyperplasia and tumor promotion. | Q44859441 | ||
| Minutes: Mutants of Drosophila autonomously affecting cell division rate | Q44889355 | ||
| Expression of an activated Notch-related int-3 transgene interferes with cell differentiation and induces neoplastic transformation in mammary and salivary glands | Q45182928 | ||
| Induction of ornithine decarboxylase activity is a necessary step for mitogen-activated protein kinase kinase-induced skin tumorigenesis. | Q45253747 | ||
| Incidence estimate of nonmelanoma skin cancer in the United States, 2006. | Q45385584 | ||
| p44 mitogen-activated protein kinase (extracellular signal-regulated kinase 1)-dependent signaling contributes to epithelial skin carcinogenesis. | Q46970873 | ||
| Distinct contribution of stem and progenitor cells to epidermal maintenance | Q47197341 | ||
| Induction of epidermal hyperplasia, hyperkeratosis, and papillomas in transgenic mice by a targeted v‐Ha‐ras oncogene | Q47636435 | ||
| Transgenic mice overexpressing protein kinase Cdelta in the epidermis are resistant to skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate | Q47906028 | ||
| Effect of genetic modification of acute inflammatory responsiveness on tumorigenesis in the mouse | Q50111007 | ||
| Safeguards for cell cooperation in mouse embryogenesis shown by genome-wide cheater screen | Q50722305 | ||
| Defining stem cell dynamics in models of intestinal tumor initiation | Q53130842 | ||
| The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells | Q53370119 | ||
| Mice deficient in tumor necrosis factor-alpha are resistant to skin carcinogenesis | Q53421778 | ||
| c-fos is required for malignant progression of skin tumors | Q53461261 | ||
| Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors | Q53478233 | ||
| v-ras genes from Harvey and BALB murine sarcoma viruses can act as initiators of two-stage mouse skin carcinogenesis | Q53535348 | ||
| Promotion of epidermal carcinogenesis by repeated damage to mouse skin | Q53546346 | ||
| Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling | Q36627008 | ||
| Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment. | Q36691086 | ||
| Transgenic overexpression of transforming growth factor alpha bypasses the need for c-Ha-ras mutations in mouse skin tumorigenesis | Q36703527 | ||
| Inflammation and Hras signaling control epithelial-mesenchymal transition during skin tumor progression. | Q36732552 | ||
| Multiple self-healing squamous epithelioma (MSSE): rare variants in an adjacent region of chromosome 9q22.3 to known TGFBR1 mutations suggest a digenic or multilocus etiology | Q36876304 | ||
| Disruption of Stat3 reveals a critical role in both the initiation and the promotion stages of epithelial carcinogenesis | Q37486563 | ||
| Carcinogen-induced mutations in the mouse c-Ha-ras gene provide evidence of multiple pathways for tumor progression | Q37671272 | ||
| The hair follicle-a stem cell zoo. | Q37718998 | ||
| Epithelial decision makers: in search of the 'epimmunome'. | Q37774241 | ||
| Multiple self-healing squamous epithelioma is caused by a disease-specific spectrum of mutations in TGFBR1. | Q38337029 | ||
| Ras-dependent regulation of c-Jun phosphorylation is mediated by the Ral guanine nucleotide exchange factor-Ral pathway | Q39540080 | ||
| Germ-line transformation of mice | Q39757195 | ||
| Mutually exclusive mutations of the Pten and ras pathways in skin tumor progression | Q40013923 | ||
| Cell replacement in epidermis (keratopoiesis) via discrete units of proliferation | Q40099956 | ||
| Promotion of Hras-induced squamous carcinomas by a polymorphic variant of the Patched gene in FVB mice | Q40182155 | ||
| An inducible mouse model for skin cancer reveals distinct roles for gain- and loss-of-function p53 mutations | Q40198133 | ||
| Akt deficiency impairs normal cell proliferation and suppresses oncogenesis in a p53-independent and mTORC1-dependent manner. | Q40219633 | ||
| Activation of the mouse cellular Harvey-ras gene in chemically induced benign skin papillomas | Q40237699 | ||
| Mouse skin: a useful model system for studying the mechanism of chemical carcinogenesis | Q40263944 | ||
| Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras | Q40424687 | ||
| RalGDS is required for tumor formation in a model of skin carcinogenesis. | Q40447001 | ||
| Essential role of tumor necrosis factor alpha (TNF-alpha) in tumor promotion as revealed by TNF-alpha-deficient mice. | Q40927961 | ||
| Inhibition of Invasion of Epithelial Cells by Tiam1-Rac Signaling | Q41075588 | ||
| Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K | Q41075804 | ||
| Tumor suppressor gene mutations in mice | Q41291379 | ||
| Induction of the formation of new hair follicles in mouse tail epidermis by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate | Q41313224 | ||
| Defining the mode of tumour growth by clonal analysis | Q41356812 | ||
| Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis | Q41390151 | ||
| Loss of heterozygosity and mutational alterations of the p53 gene in skin tumours of interspecific hybrid mice | Q41654720 | ||
| Genetic changes in skin tumor progression: correlation between presence of a mutant ras gene and loss of heterozygosity on mouse chromosome 7. | Q41734552 | ||
| Epidermal Notch1 loss promotes skin tumorigenesis by impacting the stromal microenvironment. | Q41826001 | ||
| Raf-1 regulates Rho signaling and cell migration | Q41887999 | ||
| Polyclonal origin of mouse skin papillomas | Q42094500 | ||
| Stimulation of human epidermal differentiation by delta-notch signalling at the boundaries of stem-cell clusters. | Q33901073 | ||
| Cutaneous squamous-cell carcinoma | Q33940050 | ||
| c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny | Q33947752 | ||
| Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation | Q34077697 | ||
| Alterations in Notch signaling in neoplastic lesions of the human cervix | Q34124673 | ||
| Selective activation of p53-mediated tumour suppression in high-grade tumours | Q34151826 | ||
| Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis | Q34162269 | ||
| A keratin 15 containing stem cell population from the hair follicle contributes to squamous papilloma development in the mouse | Q34202603 | ||
| Interactions between cancer stem cells and their niche govern metastatic colonization | Q34239769 | ||
| Adult epidermal Notch activity induces dermal accumulation of T cells and neural crest derivatives through upregulation of jagged 1 | Q34240735 | ||
| Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters. | Q34278348 | ||
| Lineage tracing reveals Lgr5+ stem cell activity in mouse intestinal adenomas | Q34291885 | ||
| Tumor formation initiated by nondividing epidermal cells via an inflammatory infiltrate | Q34358943 | ||
| Stage-specific sensitivity to p53 restoration during lung cancer progression. | Q34412341 | ||
| Stem cell depletion through epidermal deletion of Rac1. | Q34440522 | ||
| R-spondin1 is essential in sex determination, skin differentiation and malignancy. | Q34573938 | ||
| The origins of oncomice: a history of the first transgenic mice genetically engineered to develop cancer | Q34688859 | ||
| Mek1/2 gene dosage determines tissue response to oncogenic Ras signaling in the skin | Q34887145 | ||
| Defining the origins of Ras/p53-mediated squamous cell carcinoma | Q34937383 | ||
| Identifying the cellular origin of squamous skin tumors | Q34938312 | ||
| B regulatory cells and the tumor-promoting actions of TNF-α during squamous carcinogenesis | Q35081453 | ||
| Stem-cell hierarchy in skin cancer | Q35141774 | ||
| Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo | Q35207717 | ||
| Temporal dissection of tumorigenesis in primary cancers | Q35275682 | ||
| Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma | Q35471421 | ||
| Genetic architecture of mouse skin inflammation and tumour susceptibility | Q35702641 | ||
| Frequent clones of p53-mutated keratinocytes in normal human skin | Q35940911 | ||
| The persistence of latent tumour cells induced in the mouse's skin by a single application of 9:10-dimethyl-1:2-benzanthracene | Q36035870 | ||
| Elevated Epidermal Thymic Stromal Lymphopoietin Levels Establish an Antitumor Environment in the Skin | Q36345757 | ||
| Hairless promotes PPARγ expression and is required for white adipogenesis | Q36382050 | ||
| p21-Activated kinase 1 is required for efficient tumor formation and progression in a Ras-mediated skin cancer model. | Q36405845 | ||
| Modelling cancer in human skin tissue | Q36422870 | ||
| Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion | Q36436367 | ||
| Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2. | Q36573355 | ||
| P433 | issue | 9 | |
| P304 | page(s) | a013623 | |
| P577 | publication date | 2014-09-02 | |
| P1433 | published in | Cold Spring Harbor Perspectives in Medicine | Q21042440 |
| P1476 | title | Modeling cutaneous squamous carcinoma development in the mouse | |
| P478 | volume | 4 |
| Q90267445 | Aryl Hydrocarbon Receptor Modulates Carcinogenesis and Maintenance of Skin Cancers |
| Q93083464 | Modulation of cancer signalling pathway(s) in two -stage mouse skin tumorigenesis by annonacin |
| Q36134453 | Novel CARD11 Mutations in Human Cutaneous Squamous Cell Carcinoma Lead to Aberrant NF-κB Regulation |
| Q28831003 | Panx3 links body mass index and tumorigenesis in a genetically heterogeneous mouse model of carcinogen-induced cancer |
| Q91496460 | Thyroid hormone induces progression and invasiveness of squamous cell carcinomas by promoting a ZEB-1/E-cadherin switch |
| Q58695408 | Time-Series Analysis of Tumorigenesis in a Murine Skin Carcinogenesis Model |
| Q34549017 | Translation from unconventional 5' start sites drives tumour initiation |
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