Selective repression of Notch pathway target gene transcription

scientific article published on 22 September 2011

Selective repression of Notch pathway target gene transcription is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/J.YDBIO.2011.09.018
P698PubMed publication ID21963536
P5875ResearchGate publication ID51685603

P2093author name stringJohn W Cave
P2860cites workGenomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domainsQ21092474
CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complexQ22008610
Translating the Histone CodeQ22065840
RBP-Jkappa/SHARP recruits CtIP/CtBP corepressors to silence Notch target genesQ24294890
Notch1 augments NF-kappaB activity by facilitating its nuclear retentionQ24297567
Segmental expression of Notch and Hairy genes in nephrogenesisQ24299797
Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexesQ24307538
NKAP is a transcriptional repressor of notch signaling and is required for T cell developmentQ24321003
Notch1 and Notch2 inhibit myeloid differentiation in response to different cytokinesQ24533662
SHARP is a novel component of the Notch/RBP-Jkappa signalling pathwayQ24534941
PTF1 is an organ-specific and Notch-independent basic helix-loop-helix complex containing the mammalian Suppressor of Hairless (RBP-J) or its paralogue, RBP-L.Q24535567
ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domainQ24548340
A histone deacetylase corepressor complex regulates the Notch signal transduction pathwayQ24598533
RING1 inhibits transactivation of RBP-J by Notch through interaction with LIM protein KyoT2Q24613736
Cooperation of JAK/STAT and Notch signaling in the Drosophila foregutQ47071840
Regulation of alphabeta/gammadelta T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signalingQ47607371
Notch-GATA synergy promotes endoderm-specific expression of ref-1 in C. elegansQ50657632
Differential expression of the Enhancer of split genes in the developing Drosophila midgut.Q51733401
Genetic and epigenetic mechanisms regulating hedgehog expression in the Drosophila wing.Q51826737
Histone chaperones ASF1 and NAP1 differentially modulate removal of active histone marks by LID-RPD3 complexes during NOTCH silencing.Q51925623
Polyhomeotic has a tumor suppressor activity mediated by repression of Notch signaling.Q51926420
Nuclear factor I gene expression in the developing forebrain.Q51962127
The Notch targets Esr1 and Esr10 are differentially regulated in Xenopus neural precursors.Q52042590
The REF-1 family of bHLH transcription factors pattern C. elegans embryos through Notch-dependent and Notch-independent pathways.Q52047995
tantalus, a potential link between Notch signalling and chromatin-remodelling complexes.Q52057475
Spatially restricted factors cooperate with notch in the regulation of Enhancer of split genes.Q52168736
Distinct expression patterns of different enhancer of split bHLH genes during embryogenesis of Drosophila melanogaster.Q52176457
Expression of Notch pathway genes in the embryonic mouse metanephros suggests a role in proximal tubule development.Q52551798
Epigenetic silencers and Notch collaborate to promote malignant tumours by Rb silencing.Q52664437
Notch4 intracellular domain binding to Smad3 and inhibition of the TGF-beta signaling.Q53851403
Notch-independent regulation of Hes-1 expression by c-Jun N-terminal kinase signaling in human endothelial cellsQ56794245
Expression of Notch pathway components in fetal and adult mouse small intestineQ73080644
Off the beaten pathway: the complex cross talk between Notch and NF-kappaBQ80146628
Genome-wide profiling of PRC1 and PRC2 Polycomb chromatin binding in Drosophila melanogasterQ40289607
Hypoxia requires notch signaling to maintain the undifferentiated cell stateQ40356897
Functional antagonism between histone H3K4 demethylases in vivoQ41555305
Notch activation stimulates transient and selective binding of Su(H)/CSL to target enhancersQ41882770
Neurog2 is a direct downstream target of the Ptf1a-Rbpj transcription complex in dorsal spinal cordQ41896964
Regulation of Hox gene activity by transcriptional elongation in DrosophilaQ42045280
Polycomb group gene mel-18 regulates early T progenitor expansion by maintaining the expression of Hes-1, a target of the Notch pathwayQ42801727
NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1.Q42976906
Direct downstream targets of proneural activators in the imaginal disc include genes involved in lateral inhibitory signalingQ45243171
Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity.Q45345853
Suppressor of hairless directly activates transcription of enhancer of split complex genes in response to Notch receptor activityQ45950823
Lateral inhibition in proneural clusters: cis-regulatory logic and default repression by Suppressor of HairlessQ46124836
Combinatorial signaling in the specification of unique cell fatesQ46692883
Gene-specific targeting of the histone chaperone asf1 to mediate silencingQ47071630
Cross-talk between the Notch and TGF-beta signaling pathways mediated by interaction of the Notch intracellular domain with Smad3Q24672178
A Foxo/Notch pathway controls myogenic differentiation and fiber type specificationQ24678520
Activated Notch1 target genes during embryonic cell differentiation depend on the cellular context and include lineage determinants and inhibitorsQ27324100
RAM-induced Allostery Facilitates Assembly of a Notch Pathway Active Transcription ComplexQ27650201
Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexesQ27665343
The PcG protein HPC2 inhibits RBP-J-mediated transcription by interacting with LIM protein KyoT2Q28235012
An essential role of Pak1 phosphorylation of SHARP in Notch signalingQ28244672
Hes genes regulate size, shape and histogenesis of the nervous system by control of the timing of neural stem cell differentiationQ28288889
Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of CortiQ28507372
Expression of Hairy/Enhancer of Split genes, Hes1 and Hes5, during murine nephron morphogenesisQ28509264
Oscillating expression of c-Hey2 in the presomitic mesoderm suggests that the segmentation clock may use combinatorial signaling through multiple interacting bHLH factorsQ28510928
Zinc finger genes Fezf1 and Fezf2 control neuronal differentiation by repressing Hes5 expression in the forebrainQ28511484
Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformationQ28589469
Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activityQ28592781
The canonical Notch signaling pathway: unfolding the activation mechanismQ29547725
Mechanisms of polycomb gene silencing: knowns and unknownsQ29614511
Foxc transcription factors directly regulate Dll4 and Hey2 expression by interacting with the VEGF-Notch signaling pathways in endothelial cellsQ33342768
The Daughterless N-terminus directly mediates synergistic interactions with Notch transcription complexes via the SPS+A DNA transcription codeQ33436069
Origin and evolution of the Notch signalling pathway: an overview from eukaryotic genomes.Q33510261
A combined ex vivo and in vivo RNAi screen for notch regulators in Drosophila reveals an extensive notch interaction network.Q33584616
Myeloid translocation gene 16 (MTG16) interacts with Notch transcription complex components to integrate Notch signaling in hematopoietic cell fate specificationQ33725493
Histone demethylase KDM5A is an integral part of the core Notch-RBP-J repressor complexQ33737810
Notch and transforming growth factor-beta (TGFbeta) signaling pathways cooperatively regulate vascular smooth muscle cell differentiationQ33885162
Identification of novel targets of CSL-dependent Notch signaling in hematopoiesisQ33921337
The notch intracellular domain can function as a coactivator for LEF-1Q34012680
Notch target gene deregulation and maintenance of the leukemogenic phenotype do not require RBP-J kappa in Ikaros null miceQ34204349
Notch dimerization is required for leukemogenesis and T-cell developmentQ34244256
Target selectivity of vertebrate notch proteins. Collaboration between discrete domains and CSL-binding site architecture determines activation probabilityQ34478018
Crystal structure of the CSL-Notch-Mastermind ternary complex bound to DNA.Q34501252
NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growthQ34582832
A mosaic genetic screen reveals distinct roles for trithorax and polycomb group genes in Drosophila eye development.Q34643323
Three habits of highly effective signaling pathways: principles of transcriptional control by developmental cell signalingQ34649230
Keeping a good pathway down: transcriptional repression of Notch pathway target genes by CSL proteinsQ34838458
Dynamic Notch signaling in neural progenitor cells and a revised view of lateral inhibitionQ34867170
Transcriptional repression in the Notch pathway: thermodynamic characterization of CSL-MINT (Msx2-interacting nuclear target protein) complexesQ34869243
A SIRT1-LSD1 corepressor complex regulates Notch target gene expression and developmentQ35058520
Structural and functional analysis of the repressor complex in the Notch signaling pathway of Drosophila melanogasterQ35188610
Hey genes in cardiovascular developmentQ35201172
Cooperative assembly of higher-order Notch complexes functions as a switch to induce transcriptionQ35844655
LIN-14 Inhibition of LIN-12 Contributes to Precision and Timing of C. elegans Vulval Fate PatterningQ35878223
Turning it up a Notch: cross-talk between TGF beta and Notch signalingQ36017991
The roles of receptor and ligand endocytosis in regulating Notch signalingQ36080178
Enhanced gene activation by Notch and BMP signaling cross-talkQ36119543
Signal integration during development: mechanisms of EGFR and Notch pathway function and cross-talkQ36648414
Transcriptional regulation by C-terminal binding proteinsQ36750450
Hairless: the ignored antagonist of the Notch signalling pathwayQ36760389
Ikaros represses the transcriptional response to Notch signaling in T-cell developmentQ36994950
ChIP-on-chip significance analysis reveals large-scale binding and regulation by human transcription factor oncogenesQ37034832
Wnt/Notch signalling and information processing during development.Q37055994
Context-dependent regulation of Groucho/TLE-mediated repressionQ37249996
It's T-ALL about NotchQ37256435
The molecular logic of Notch signaling--a structural and biochemical perspective.Q37272381
The Notch signaling pathway: transcriptional regulation at Notch target genesQ37376057
Ikaros regulates Notch target gene expression in developing thymocytesQ37424241
The dawn of developmental signaling in the metazoaQ37630809
Mechanistic insights into Notch receptor signaling from structural and biochemical studiesQ37785192
The Notch signaling pathway: molecular basis of cell context dependencyQ37815315
The Ikaros gene family: transcriptional regulators of hematopoiesis and immunityQ37863312
Discrete enhancer elements mediate selective responsiveness of enhancer of split complex genes to common transcriptional activatorsQ38321559
A DNA transcription code for cell-specific gene activation by notch signalingQ38331498
Differential Regulation of Transcription through Distinct Suppressor of Hairless DNA Binding Site Architectures during Notch Signaling in Proneural ClustersQ38339670
Perturbation of Ikaros isoform selection by MLV integration is a cooperative event in Notch(IC)-induced T cell leukemogenesisQ38352939
Regulation of the Notch target gene Hes-1 by TGFalpha induced Ras/MAPK signaling in human neuroblastoma cellsQ38446384
Synergy and antagonism between Notch and BMP receptor signaling pathways in endothelial cells.Q39320608
BCL6 canalizes Notch-dependent transcription, excluding Mastermind-like1 from selected target genes during left-right patterningQ39684544
ATF2 maintains a subset of neural progenitors through CBF1/Notch independent Hes-1 expression and synergistically activates the expression of Hes-1 in Notch-dependent neural progenitorsQ39753122
Ikaros directly represses the notch target gene Hes1 in a leukemia T cell line: implications for CD4 regulationQ39782908
Structural rules and complex regulatory circuitry constrain expression of a Notch- and EGFR-regulated eye enhancerQ39846861
Zfp64 participates in Notch signaling and regulates differentiation in mesenchymal cellsQ39989350
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)123-131
P577publication date2011-09-22
P1433published inDevelopmental BiologyQ3025402
P1476titleSelective repression of Notch pathway target gene transcription
P478volume360

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cites work (P2860)
Q38003146Molecular pathways of notch signaling in vascular smooth muscle cells
Q34281265Photoactivation of bone marrow mesenchymal stromal cells with diode laser: effects and mechanisms of action.