Keeping a good pathway down: transcriptional repression of Notch pathway target genes by CSL proteins

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Keeping a good pathway down: transcriptional repression of Notch pathway target genes by CSL proteins is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1093/EMBO-REPORTS/KVF170
P932PMC publication ID1084223
P698PubMed publication ID12223465
P5875ResearchGate publication ID11167011

P50authorEric C LaiQ52431492
P2860cites workCIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complexQ22008610
SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC functionQ22253329
MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptorsQ24290574
A human protein with sequence similarity to Drosophila mastermind coordinates the nuclear form of notch and a CSL protein to build a transcriptional activator complex on target promotersQ24291301
The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2Q24293216
Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressorQ24311650
Net, a negative Ras-switchable TCF, contains a second inhibition domain, the CID, that mediates repression through interactions with CtBP and de-acetylationQ24534166
p300 acts as a transcriptional coactivator for mammalian Notch-1Q24548267
Nuclear localization of CBF1 is regulated by interactions with the SMRT corepressor complexQ24550850
A histone deacetylase corepressor complex regulates the Notch signal transduction pathwayQ24598533
Truncated mammalian Notch1 activates CBF1/RBPJk-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2Q24650743
Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complexQ24675233
Notch signaling: cell fate control and signal integration in developmentQ27861061
The coregulator exchange in transcriptional functions of nuclear receptorsQ28131759
The neurogenic suppressor of hairless DNA-binding protein mediates the transcriptional activation of the enhancer of split complex genes triggered by Notch signaling.Q47072129
Inhibition of the DNA-binding activity of Drosophila suppressor of hairless and of its human homolog, KBF2/RBP-J kappa, by direct protein-protein interaction with Drosophila hairlessQ47072311
The suppressor of hairless protein participates in notch receptor signalingQ47072502
A model Notch response element detects Suppressor of Hairless-dependent molecular switch.Q52141250
Two different activities of Suppressor of Hairless during wing development in Drosophila.Q52166706
Suppressor of hairless, the Drosophila homologue of RBP-J kappa, transactivates the neurogenic gene E(spl)m8.Q52207063
An EGFR/Ebi/Sno pathway promotes delta expression by inactivating Su(H)/SMRTER repression during inductive notch signaling.Q52599088
Notch signaling: from the outside inQ28139768
Association of COOH-terminal-binding protein (CtBP) and MEF2-interacting transcription repressor (MITR) contributes to transcriptional repression of the MEF2 transcription factorQ28140525
Functional interaction between the mouse notch1 intracellular region and histone acetyltransferases PCAF and GCN5Q28140561
CtBP, an unconventional transcriptional corepressor in development and oncogenesisQ28203691
The CtBP family: enigmatic and enzymatic transcriptional co-repressorsQ28211777
Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteinsQ28243184
A protein binding to the J kappa recombination sequence of immunoglobulin genes contains a sequence related to the integrase motifQ28255047
SAP30, a component of the mSin3 corepressor complex involved in N-CoR-mediated repression by specific transcription factorsQ28279441
A transcriptional co-repressor that interacts with nuclear hormone receptorsQ28289864
Brinker requires two corepressors for maximal and versatile repression in Dpp signallingQ28361365
A functional interaction between the histone deacetylase Rpd3 and the corepressor groucho in Drosophila developmentQ28609065
The homeodomain protein NK-3 recruits Groucho and a histone deacetylase complex to repress transcriptionQ28609066
A role for Groucho tetramerization in transcriptional repressionQ28609165
The SMRT and N-CoR corepressors are activating cofactors for histone deacetylase 3Q28609763
Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylaseQ29547913
Drosophila CtBP: a Hairy-interacting protein required for embryonic segmentation and hairy-mediated transcriptional repressionQ33888622
LAG-3 is a putative transcriptional activator in the C. elegans Notch pathwayQ33903634
Transcriptional repression: the long and the short of it.Q34426886
Protein degradation: four E3s for the notch pathwayQ34511141
Groucho and dCtBP mediate separate pathways of transcriptional repression in the Drosophila embryoQ34820104
Repression by suppressor of hairless and activation by Notch are required to define a single row of single-minded expressing cells in the Drosophila embryo.Q35186143
The mammalian transcriptional repressor RBP (CBF1) targets TFIID and TFIIA to prevent activated transcriptionQ35201509
The Epstein-Barr virus nuclear antigen 2 transactivator is directed to response elements by the J kappa recombination signal binding proteinQ35648541
Default repression and Notch signaling: Hairless acts as an adaptor to recruit the corepressors Groucho and dCtBP to Suppressor of HairlessQ35779716
The recombination signal sequence-binding protein RBP-2N functions as a transcriptional repressorQ36652805
Dissecting the mechanisms of suppressor of hairless functionQ38306844
Drosophila C-terminal binding protein functions as a context-dependent transcriptional co-factor and interferes with both mad and groucho transcriptional repressionQ38308579
Recognition sequence of a highly conserved DNA binding protein RBP-J kappaQ38309890
RBP-J kappa repression activity is mediated by a co-repressor and antagonized by the Epstein-Barr virus transcription factor EBNA2.Q40397055
Suppressor of Hairless, the Drosophila homolog of the mouse recombination signal-binding protein gene, controls sensory organ cell fatesQ43575150
Transcriptional repression by suppressor of hairless involves the binding of a hairless-dCtBP complex in Drosophila.Q43621582
Masking of the CBF1/RBPJ kappa transcriptional repression domain by Epstein-Barr virus EBNA2.Q44697821
Mediation of Epstein-Barr virus EBNA2 transactivation by recombination signal-binding protein J kappaQ45781476
Suppressor of hairless directly activates transcription of enhancer of split complex genes in response to Notch receptor activityQ45950823
Hairless promotes stable commitment to the sensory organ precursor cell fate by negatively regulating the activity of the Notch signaling pathwayQ46246453
Antagonistic activities of Suppressor of Hairless and Hairless control alternative cell fates in the Drosophila adult epidermis.Q46371601
A notch-independent activity of suppressor of hairless is required for normal mechanoreceptor physiologyQ46703801
P433issue9
P304page(s)840-845
P577publication date2002-09-01
P1433published inEMBO ReportsQ5323356
P1476titleKeeping a good pathway down: transcriptional repression of Notch pathway target genes by CSL proteins
P478volume3