ARF induction in response to DNA strand breaks is regulated by PARP1.

scientific article published on 29 November 2013

ARF induction in response to DNA strand breaks is regulated by PARP1. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/NAR/GKT1185
P932PMC publication ID3936746
P698PubMed publication ID24293653
P5875ResearchGate publication ID259111334

P2093author name stringGrigory L Dianov
Irina I Dianova
Jason L Parsons
Svetlana V Khoronenkova
Giulia Orlando
P2860cites workDeficiency in Poly(ADP-ribose) Polymerase-1 (PARP-1) Accelerates Aging and Spontaneous Carcinogenesis in MiceQ21342802
Instability and decay of the primary structure of DNAQ22122361
The role of poly(ADP-ribose) in the DNA damage signaling networkQ22306473
Poly(ADP-ribose) polymerase-1 modulates DNA repair capacity and prevents formation of DNA double strand breaksQ39983326
Control of AIF-mediated cell death by the functional interplay of SIRT1 and PARP-1 in response to DNA damageQ40289662
A vital role for Ape1/Ref1 protein in repairing spontaneous DNA damage in human cells.Q40461671
p14ARF is a component of the p53 response following ionizing irradiation of normal human fibroblastsQ40545765
Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaksQ40593721
Poly(ADP-ribose) polymerase-1 is a positive regulator of the p53-mediated G1 arrest response following ionizing radiationQ40663274
PARP-1 modifies the effectiveness of p53-mediated DNA damage response.Q40750146
PARP-1 ensures regulation of replication fork progression by homologous recombination on damaged DNA.Q41867379
Poly(ADP-ribose) polymerase-1 regulates the stability of the wild-type p53 protein.Q42509775
Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stressQ42811705
Are poly(ADP-ribosyl)ation by PARP-1 and deacetylation by Sir2 linked?Q44524722
p16INK⁴a and p14ARF mRNA expression in Pap smears is age-relatedQ50507882
Functional interplay between Parp-1 and SirT1 in genome integrity and chromatin-based processes.Q52595108
p14ARF links the tumour suppressors RB and p53.Q55067966
p19ARF links the tumour suppressor p53 to RasQ57562848
c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instabilityQ74243929
Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damageQ24299098
Transcription-independent ARF regulation in oncogenic stress-mediated p53 responsesQ24301836
ARF-BP1/Mule is a critical mediator of the ARF tumor suppressorQ24306428
Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosisQ24306444
Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatinQ24306469
Ubiquitin ligase ARF-BP1/Mule modulates base excision repairQ24310413
Enzymes in the NAD+ salvage pathway regulate SIRT1 activity at target gene promotersQ24314812
Rereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpointQ24563819
XRCC1 is required for DNA single-strand break repair in human cellsQ24796404
Divorcing ARF and p53: an unsettled caseQ28258356
Ink4a/Arf expression is a biomarker of agingQ28570483
Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.Q28590239
Promoter-selective activation domains in Oct-1 and Oct-2 direct differential activation of an snRNA and mRNA promoterQ28620733
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replicationQ29617915
p53 in health and diseaseQ29619939
The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53.Q33781484
The ARF/p53 pathwayQ33840421
Ageing: longevity hits a roadblockQ34218299
Mammalian base excision repair: the forgotten archangelQ34327812
The PARP superfamilyQ34335821
Basal dynamics of p53 reveal transcriptionally attenuated pulses in cycling cells.Q34414003
p14ARF activates a Tip60-dependent and p53-independent ATM/ATR/CHK pathway in response to genotoxic stressQ34717991
XRCC1 and DNA strand break repairQ35216366
Quantitation of intracellular NAD(P)H can monitor an imbalance of DNA single strand break repair in base excision repair deficient cells in real timeQ36247999
Regulation of the INK4b-ARF-INK4a tumour suppressor locus: all for one or one for all.Q36572080
RNA interference directed against Poly(ADP-Ribose) polymerase 1 efficiently suppresses human immunodeficiency virus type 1 replication in human cellsQ36684320
Poly ADP-ribose polymerase-1: an international molecule of mysteryQ37158860
The Arf/p53 pathway in cancer and agingQ37234165
The emerging role of Mule and ARF in the regulation of base excision repairQ37897323
Acute loss of transcription factor E2F1 induces mitochondrial biogenesis in HeLa cellsQ38309669
Topoisomerase I poisoning results in PARP-mediated replication fork reversalQ39386006
Distinct E2F-mediated transcriptional program regulates p14ARF gene expressionQ39491071
The role of sirtuin 1 in osteoblastic differentiation in human periodontal ligament cellsQ39509060
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P433issue4
P304page(s)2320-2329
P577publication date2013-11-29
P1433published inNucleic Acids ResearchQ135122
P1476titleARF induction in response to DNA strand breaks is regulated by PARP1.
P478volume42

Reverse relations

cites work (P2860)
Q28828468(±)-Japonones A and B, two pairs of new enantiomers with anti-KSHV activities from Hypericum japonicum
Q28254419A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol
Q35476632Cells deficient in base-excision repair reveal cancer hallmarks originating from adjustments to genetic instability
Q42506553Differing tumor-suppressor functions of Arf and p53 in murine basal cell carcinoma initiation and progression
Q38993869Epigenetic regulation of cancer biology and anti-tumor immunity by EZH2.
Q58796631Interplay between base excision repair protein XRCC1 and ALDH2 predicts overall survival in lung and liver cancer patients
Q40459014MKK7 and ARF: new players in the DNA damage response scenery.
Q42040194Modulation of proteostasis counteracts oxidative stress and affects DNA base excision repair capacity in ATM-deficient cells
Q55078362Persistent DNA strand breaks induce a CAF-like phenotype in normal fibroblasts.
Q28834500p53 coordinates base excision repair to prevent genomic instability

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