| scholarly article | Q13442814 |
| P50 | author | Shunichi Takeda | Q62588214 |
| Shin-Ichiro Takebayashi | Q91352466 | ||
| Hiroshi Taguchi | Q101344117 | ||
| Katsuzumi Okumura | Q117843655 | ||
| Kazuto Sugimura | Q117843662 | ||
| P2860 | cites work | Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1 | Q24297360 |
| Identification and biochemical characterization of a Werner's syndrome protein complex with Ku70/80 and poly(ADP-ribose) polymerase-1 | Q24305550 | ||
| Functional association of poly(ADP-ribose) polymerase with DNA polymerase alpha-primase complex: a link between DNA strand break detection and DNA replication | Q24319674 | ||
| XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage | Q24522502 | ||
| Physical and functional interaction between DNA ligase IIIalpha and poly(ADP-Ribose) polymerase 1 in DNA single-strand break repair | Q24679360 | ||
| Repair of and checkpoint response to topoisomerase I-mediated DNA damage | Q28187875 | ||
| Human proliferating cell nuclear antigen, poly(ADP-ribose) polymerase-1, and p21waf1/cip1. A dynamic exchange of partners | Q28202875 | ||
| Differential effects of the poly (ADP-ribose) polymerase (PARP) inhibitor NU1025 on topoisomerase I and II inhibitor cytotoxicity in L1210 cells in vitro | Q28345489 | ||
| The effect of Hus1 on ionizing radiation sensitivity is associated with homologous recombination repair but is independent of nonhomologous end-joining | Q28505397 | ||
| Involvement of Hus1 in the chain elongation step of DNA replication after exposure to camptothecin or ionizing radiation | Q28509716 | ||
| Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells | Q29617437 | ||
| A new XRCC1-containing complex and its role in cellular survival of methyl methanesulfonate treatment | Q33292074 | ||
| Dynamic molecular combing: stretching the whole human genome for high-resolution studies. | Q34437508 | ||
| Parp-1 protects homologous recombination from interference by Ku and Ligase IV in vertebrate cells | Q34500845 | ||
| Homologous and non-homologous recombination differentially affect DNA damage repair in mice | Q35008336 | ||
| RNA interference directed against Poly(ADP-Ribose) polymerase 1 efficiently suppresses human immunodeficiency virus type 1 replication in human cells | Q36684320 | ||
| Poly(ADP-ribose) polymerase and Ku autoantigen form a complex and synergistically bind to matrix attachment sequences | Q38322936 | ||
| XRCC1 polypeptide interacts with DNA polymerase beta and possibly poly (ADP-ribose) polymerase, and DNA ligase III is a novel molecular 'nick-sensor' in vitro | Q39718210 | ||
| DNA double-strand breaks associated with replication forks are predominantly repaired by homologous recombination involving an exchange mechanism in mammalian cells | Q40814143 | ||
| Similar effects of Brca2 truncation and Rad51 paralog deficiency on immunoglobulin V gene diversification in DT40 cells support an early role for Rad51 paralogs in homologous recombination | Q40890780 | ||
| Suppression of the poly(ADP-ribose) polymerase activity by DNA-dependent protein kinase in vitro | Q40932301 | ||
| Establishment and some mutational characteristics of 3T3-like near-diploid mouse cell line | Q42808367 | ||
| Association of XRCC1 and tyrosyl DNA phosphodiesterase (Tdp1) for the repair of topoisomerase I-mediated DNA lesions | Q44588288 | ||
| A Positive Role for the Ku Complex in DNA Replication Following Strand Break Damage in Mammals | Q44655898 | ||
| Replication fork reactivation downstream of a blocked nascent leading strand | Q46923728 | ||
| Poly(ADP-ribosyl)ation as a DNA damage-induced post-translational modification regulating poly(ADP-ribose) polymerase-1-topoisomerase I interaction | Q47215091 | ||
| XRCC3 and Rad51 modulate replication fork progression on damaged vertebrate chromosomes | Q47948111 | ||
| Camptothecin hypersensitivity in poly(adenosine diphosphate-ribose) polymerase-deficient cell lines. | Q54367354 | ||
| Antitumour drugs impede DNA uncoiling by topoisomerase I | Q59092676 | ||
| P433 | issue | 7 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1203-1212 | |
| P577 | publication date | 2008-12-22 | |
| P1433 | published in | Journal of Cell Biology | Q1524550 |
| P1476 | title | PARP-1 ensures regulation of replication fork progression by homologous recombination on damaged DNA. | |
| P478 | volume | 183 |
| Q50016236 | A Phase I Clinical Trial of the Poly(ADP-ribose) Polymerase Inhibitor Veliparib and Weekly Topotecan in Patients with Solid Tumors |
| Q35923641 | A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells. |
| Q53091826 | A single-molecule approach to DNA replication in Escherichia coli cells demonstrated that DNA polymerase III is a major determinant of fork speed. |
| Q41914293 | ARF induction in response to DNA strand breaks is regulated by PARP1. |
| Q34539782 | BRCA1, PARP, and 53BP1: conditional synthetic lethality and synthetic viability |
| Q42929252 | BRCA2 and RAD51 promote double-strand break formation and cell death in response to gemcitabine. |
| Q30873820 | Barrier-to-autointegration factor proteome reveals chromatin-regulatory partners |
| Q90482969 | Blocking c-Met and EGFR reverses acquired resistance of PARP inhibitors in triple-negative breast cancer |
| Q35883264 | Chromatin maintenance by a molecular motor protein |
| Q48097137 | Chromatin remodeler ALC1 prevents replication-fork collapse by slowing fork progression |
| Q34300803 | Contextual synthetic lethality of cancer cell kill based on the tumor microenvironment. |
| Q37117765 | Cyclin A-Cdk1 regulates the origin firing program in mammalian cells |
| Q38245166 | DNA single-strand break repair |
| Q33690563 | FANCM regulates DNA chain elongation and is stabilized by S-phase checkpoint signalling |
| Q53707073 | Fork Protection and Therapy Resistance in Hereditary Breast Cancer. |
| Q28391355 | Genome stability pathways in head and neck cancers |
| Q37499042 | Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition |
| Q38966735 | Identification of a putative Tdp1 inhibitor (CD00509) by in vitro and cell-based assays. |
| Q44735471 | Inhibition of poly(ADP-ribose) glycohydrolase (PARG) specifically kills BRCA2-deficient tumor cells |
| Q51588092 | Inter-origin cooperativity of geminin action establishes an all-or-none switch for replication origin licensing. |
| Q47109838 | Kinetics of poly(ADP-ribosyl)ation, but not PARP1 itself, determines the cell fate in response to DNA damage in vitro and in vivo |
| Q92612315 | Mitotic functions of poly(ADP-ribose) polymerases |
| Q49700613 | Monitoring of the spatial and temporal dynamics of BER/SSBR pathway proteins, including MYH, UNG2, MPG, NTH1 and NEIL1-3, during DNA replication |
| Q35395549 | New paradigms in the repair of oxidative damage in human genome: mechanisms ensuring repair of mutagenic base lesions during replication and involvement of accessory proteins. |
| Q89581155 | Nuclear PARPs and genome integrity |
| Q33843183 | PARG is dispensable for recovery from transient replicative stress but required to prevent detrimental accumulation of poly(ADP-ribose) upon prolonged replicative stress |
| Q37022423 | PARP activation promotes nuclear AID accumulation in lymphoma cells |
| Q89581160 | PARP and PARG inhibitors in cancer treatment |
| Q39425287 | PARP inhibition sensitizes childhood high grade glioma, medulloblastoma and ependymoma to radiation. |
| Q39169663 | PARP inhibition sensitizes to low dose-rate radiation TMPRSS2-ERG fusion gene-expressing and PTEN-deficient prostate cancer cells |
| Q29619617 | PARP inhibition: PARP1 and beyond |
| Q50076626 | PARP inhibitors: Clinical utility and possibilities of overcoming resistance |
| Q35156963 | PARP regulates nonhomologous end joining through retention of Ku at double-strand breaks |
| Q37377750 | PARP-1 deficiency increases the severity of disease in a mouse model of multiple sclerosis |
| Q36016459 | PARP-1 deletion promotes subventricular zone neural stem cells toward a glial fate |
| Q36056495 | PARP-2 sustains erythropoiesis in mice by limiting replicative stress in erythroid progenitors. |
| Q24324178 | PARP-3 and APLF function together to accelerate nonhomologous end-joining |
| Q50277644 | PARP1 and PARP2 stabilise replication forks at base excision repair intermediates through Fbh1-dependent Rad51 regulation. |
| Q42922896 | PARP1 is activated at telomeres upon G4 stabilization: possible target for telomere-based therapy |
| Q37701295 | PARP1-TDP1 coupling for the repair of topoisomerase I-induced DNA damage |
| Q24619372 | Partial complementation of a DNA ligase I deficiency by DNA ligase III and its impact on cell survival and telomere stability in mammalian cells |
| Q36786691 | Pegylated siRNA-loaded calcium phosphate nanoparticle-driven amplification of cancer cell internalization in vivo |
| Q90478703 | Poly(ADP-Ribose)Polymerase (PARP) Inhibitors and Radiation Therapy |
| Q39041714 | Poly(ADP-ribose) binding to Chk1 at stalled replication forks is required for S-phase checkpoint activation |
| Q34946954 | Poly(ADP-ribose) polymerase and XPF-ERCC1 participate in distinct pathways for the repair of topoisomerase I-induced DNA damage in mammalian cells |
| Q39551829 | Poly(ADP-ribose) polymers regulate DNA topoisomerase I (Top1) nuclear dynamics and camptothecin sensitivity in living cells |
| Q38155805 | Poly(ADP-ribosyl)ation in regulation of chromatin structure and the DNA damage response |
| Q38137764 | Predictive biomarkers for cancer therapy with PARP inhibitors. |
| Q22001505 | Proteomic dissection of cell type-specific H2AX-interacting protein complex associated with hepatocellular carcinoma |
| Q35693354 | Pyrimidine Pool Disequilibrium Induced by a Cytidine Deaminase Deficiency Inhibits PARP-1 Activity, Leading to the Under Replication of DNA. |
| Q35141185 | Rad51-mediated replication fork reversal is a global response to genotoxic treatments in human cells |
| Q47360676 | Radiosensitization with an inhibitor of poly(ADP-ribose) glycohydrolase: A comparison with the PARP1/2/3 inhibitor olaparib |
| Q33603605 | Rationale for poly(ADP-ribose) polymerase (PARP) inhibitors in combination therapy with camptothecins or temozolomide based on PARP trapping versus catalytic inhibition |
| Q35089091 | Recombinase and translesion DNA polymerase decrease the speed of replication fork progression during the DNA damage response in Escherichia coli cells |
| Q42368008 | Redundancy between nucleases required for homologous recombination promotes PARP inhibitor resistance in the eukaryotic model organism Dictyostelium. |
| Q61813059 | Replisome Dynamics and Their Functional Relevance upon DNA Damage through the PCNA Interactome |
| Q26765457 | Roles of RNA-Binding Proteins in DNA Damage Response |
| Q33558275 | SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage. |
| Q57066099 | Sensitization of Cancer Cells to Radiation and Topoisomerase I Inhibitor Camptothecin Using Inhibitors of PARP and Other Signaling Molecules |
| Q97568888 | Sequential role of RAD51 paralog complexes in replication fork remodeling and restart |
| Q42318913 | Site-specific ADP-ribosylation of histone H2B in response to DNA double strand breaks. |
| Q45904455 | Slow down, enzymes at work. |
| Q47761787 | Small-Molecule Inhibitors Targeting DNA Repair and DNA Repair Deficiency in Research and Cancer Therapy |
| Q38932626 | Specific killing of DNA damage-response deficient cells with inhibitors of poly(ADP-ribose) glycohydrolase |
| Q26991603 | Synthetic lethality and cancer: cohesin and PARP at the replication fork |
| Q36832574 | The Arf/p53 protein module, which induces apoptosis, down-regulates histone H2AX to allow normal cells to survive in the presence of anti-cancer drugs |
| Q58859255 | The Importance of Poly(ADP-Ribose) Polymerase as a Sensor of Unligated Okazaki Fragments during DNA Replication |
| Q50198142 | The Mcm2-7-interacting domain of human mini-chromosome maintenance 10 (Mcm10) protein is important for stable chromatin association and origin firing |
| Q35679372 | The XRCC1 phosphate-binding pocket binds poly (ADP-ribose) and is required for XRCC1 function |
| Q34189234 | The alternative end-joining pathway for repair of DNA double-strand breaks requires PARP1 but is not dependent upon microhomologies |
| Q95267029 | The dynamic landscape of BRCA1 reversion mutations from indel to SNV in a patient with ovarian cancer treated with PARP-inhibitors and immunotherapy |
| Q38111467 | The expanding role of PARPs in the establishment and maintenance of heterochromatin. |
| Q38263955 | The histone chaperone facilitates chromatin transcription (FACT) protein maintains normal replication fork rates |
| Q39414183 | The multifaceted roles of PARP1 in DNA repair and chromatin remodelling. |
| Q34029929 | The role of ADP-ribosylation in regulating DNA double-strand break repair |
| Q27727978 | The role of ADP-ribosylation in regulating DNA interstrand crosslink repair |
| Q39020576 | Tipin functions in the protection against topoisomerase I inhibitor |
| Q39386006 | Topoisomerase I poisoning results in PARP-mediated replication fork reversal |
| Q38219235 | Transcriptional roles of PARP1 in cancer |
| Q26745673 | Trial watch - inhibiting PARP enzymes for anticancer therapy |
| Q33875792 | Tyrosyl-DNA-phosphodiesterases (TDP1 and TDP2). |
| Q37215337 | XRCC1 interacts with the p58 subunit of DNA Pol alpha-primase and may coordinate DNA repair and replication during S phase. |
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