| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1029662881 |
| P356 | DOI | 10.1007/S00109-010-0606-5 |
| P698 | PubMed publication ID | 20419447 |
| P2093 | author name string | Bernd Dörken | |
| Jana Wendt | |||
| Peter T Daniel | |||
| Philipp G Hemmati | |||
| Tim Overkamp | |||
| Bernd Gillissen | |||
| Annika Müer | |||
| Ana Milojkovic | |||
| P2860 | cites work | PUMA induces the rapid apoptosis of colorectal cancer cells | Q24291462 |
| Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis | Q24300313 | ||
| PUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cells | Q24316443 | ||
| p14ARF induces G2 cell cycle arrest in p53- and p21-deficient cells by down-regulating p34cdc2 kinase activity | Q24319978 | ||
| Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members | Q24337108 | ||
| PUMA mediates the apoptotic response to p53 in colorectal cancer cells | Q24550772 | ||
| The Bcl-2 apoptotic switch in cancer development and therapy | Q24620437 | ||
| Puma cooperates with Bim, the rate-limiting BH3-only protein in cell death during lymphocyte development, in apoptosis induction | Q24677017 | ||
| Induction of cell death by the BH3-only Bcl-2 homolog Nbk/Bik is mediated by an entirely Bax-dependent mitochondrial pathway | Q24681629 | ||
| Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity | Q28138855 | ||
| p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa | Q28204059 | ||
| Puma is an essential mediator of p53-dependent and -independent apoptotic pathways | Q28213279 | ||
| Principles of tumor suppression | Q28240740 | ||
| Divorcing ARF and p53: an unsettled case | Q28258356 | ||
| Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest | Q28270478 | ||
| p21 is necessary for the p53-mediated G1 arrest in human cancer cells | Q28291118 | ||
| Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization | Q29614701 | ||
| BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly | Q29617135 | ||
| Dissecting the pathways to death | Q33181665 | ||
| Guardians of cell death: the Bcl-2 family proteins | Q33194324 | ||
| Loss of p21 disrupts p14 ARF-induced G1 cell cycle arrest but augments p14 ARF-induced apoptosis in human carcinoma cells | Q33212599 | ||
| Loss of the tissue-specific proapoptotic BH3-only protein Nbk/Bik is a unifying feature of renal cell carcinoma. | Q33228343 | ||
| Induction of p21CIP/WAF-1 and G2 arrest by ionizing irradiation impedes caspase-3-mediated apoptosis in human carcinoma cells | Q33228616 | ||
| Bak functionally complements for loss of Bax during p14ARF-induced mitochondrial apoptosis in human cancer cells | Q33250477 | ||
| Frequent loss of expression of the pro-apoptotic protein Bim in renal cell carcinoma: evidence for contribution to apoptosis resistance. | Q33283940 | ||
| Mcl-1 determines the Bax dependency of Nbk/Bik-induced apoptosis | Q33306334 | ||
| Cooperative effect of p21Cip1/WAF-1 and 14-3-3sigma on cell cycle arrest and apoptosis induction by p14ARF. | Q33370904 | ||
| BH3-Only proteins-essential initiators of apoptotic cell death | Q34117362 | ||
| BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak | Q35079498 | ||
| E1A signaling to p53 involves the p19(ARF) tumor suppressor | Q35206764 | ||
| Life in the balance: how BH3-only proteins induce apoptosis. | Q36294226 | ||
| BH3-only proteins in cell death initiation, malignant disease and anticancer therapy. | Q36463059 | ||
| p19(Arf) induces p53-dependent apoptosis during abelson virus-mediated pre-B cell transformation | Q36645083 | ||
| Targeting the Bcl-2-regulated apoptosis pathway by BH3 mimetics: a breakthrough in anticancer therapy? | Q37120213 | ||
| The endoplasmic reticulum in apoptosis and autophagy: role of the BCL-2 protein family. | Q37310187 | ||
| Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis | Q38326924 | ||
| Apoptosis-based dual molecular targeting by INNO-406, a second-generation Bcr-Abl inhibitor, and ABT-737, an inhibitor of antiapoptotic Bcl-2 proteins, against Bcr-Abl-positive leukemia | Q40131183 | ||
| The multiple battles fought by anti-apoptotic p21. | Q40168692 | ||
| Cyclin-dependent kinase inhibitors uncouple cell cycle progression from mitochondrial apoptotic functions in DNA-damaged cancer cells. | Q40400655 | ||
| Key roles of BIM-driven apoptosis in epithelial tumors and rational chemotherapy. | Q40446996 | ||
| The first alpha helix of Bax plays a necessary role in its ligand-induced activation by the BH3-only proteins Bid and PUMA. | Q40485961 | ||
| Apoptosis resistance of MCF-7 breast carcinoma cells to ionizing radiation is independent of p53 and cell cycle control but caused by the lack of caspase-3 and a caffeine-inhibitable event | Q40507958 | ||
| BH3-only proteins Puma and Bim are rate-limiting for gamma-radiation- and glucocorticoid-induced apoptosis of lymphoid cells in vivo. | Q41837676 | ||
| Overlapping cleavage motif selectivity of caspases: implications for analysis of apoptotic pathways. | Q50659185 | ||
| p14ARF triggers G2 arrest through ERK-mediated Cdc25C phosphorylation, ubiquitination and proteasomal degradation. | Q53629313 | ||
| p53- and Mdm2-Independent Repression of NF-κB Transactivation by the ARF Tumor Suppressor | Q58287158 | ||
| Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies | Q79370601 | ||
| p21 blocks irradiation-induced apoptosis downstream of mitochondria by inhibition of cyclin-dependent kinase-mediated caspase-9 activation | Q79405060 | ||
| P433 | issue | 6 | |
| P921 | main subject | cell death | Q2383867 |
| P304 | page(s) | 609-622 | |
| P577 | publication date | 2010-04-25 | |
| P1433 | published in | Journal of Molecular Medicine | Q6295593 |
| P1476 | title | Systematic genetic dissection of p14ARF-mediated mitochondrial cell death signaling reveals a key role for p21CDKN1 and the BH3-only protein Puma/bbc3. | |
| P478 | volume | 88 |
| Q36268430 | Bax/Bak-independent mitochondrial depolarization and reactive oxygen species induction by sorafenib overcome resistance to apoptosis in renal cell carcinoma |
| Q28478852 | Modeling of miRNA and drug action in the EGFR signaling pathway |
| Q61447783 | Overexpression of CCDC69 activates p14/MDM2/p53 pathway and confers cisplatin sensitivity |
| Q34166041 | p14(ARF)-induced apoptosis in p53 protein-deficient cells is mediated by BH3-only protein-independent derepression of Bak protein through down-regulation of Mcl-1 and Bcl-xL proteins. |
| Q34728302 | p14ARF induces apoptosis via an entirely caspase-3-dependent mitochondrial amplification loop. |
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