| scholarly article | Q13442814 |
| P356 | DOI | 10.1158/0008-5472.CAN-10-3483 |
| P8608 | Fatcat ID | release_xanrxhp7zjbznp52poqvfxgo7i |
| P932 | PMC publication ID | 3227421 |
| P698 | PubMed publication ID | 21447739 |
| P2093 | author name string | Yaxue Zeng | |
| Yue Xiong | |||
| Matthew D Smith | |||
| Yojiro Kotake | |||
| Xin-Hai Pei | |||
| P2860 | cites work | The Drosophila Polycomb Group proteins ESC and E(Z) are present in a complex containing the histone-binding protein p55 and the histone deacetylase RPD3 | Q24290657 |
| ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways | Q24321528 | ||
| A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4 | Q24322196 | ||
| Mdm2 promotes the rapid degradation of p53 | Q24322597 | ||
| Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53 | Q24328775 | ||
| Repression of p53-mediated transcription by MDM2: a dual mechanism | Q24336020 | ||
| Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways | Q24529593 | ||
| Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS | Q24657459 | ||
| The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells | Q24680814 | ||
| In vivo activation of the p53 pathway by small-molecule antagonists of MDM2 | Q27642888 | ||
| Tumor surveillance via the ARF-p53 pathway. | Q53430438 | ||
| Upregulation of mdm-2 expression in Meth A tumor cells tolerating wild-type p53 | Q72904076 | ||
| Evidence for a negative-feedback mechanism in the biosynthesis of isoleucine | Q74050399 | ||
| Regulation of p53 stability by Mdm2 | Q27860744 | ||
| Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation | Q28139187 | ||
| Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells | Q28201183 | ||
| Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein | Q28238628 | ||
| The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence | Q28245403 | ||
| Divorcing ARF and p53: an unsettled case | Q28258356 | ||
| The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53 | Q28266637 | ||
| The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation | Q28280958 | ||
| Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing | Q28287373 | ||
| p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression | Q28300071 | ||
| p53 mutations in human cancers | Q28302973 | ||
| Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice | Q28511962 | ||
| The p53-mdm-2 autoregulatory feedback loop | Q28609811 | ||
| Blinded by the Light: The Growing Complexity of p53 | Q29547590 | ||
| Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization | Q29614701 | ||
| Transcriptional control of human p53-regulated genes | Q29617650 | ||
| mdm2 expression is induced by wild type p53 activity | Q29618316 | ||
| The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus | Q29619815 | ||
| The screening of the second-site suppressor mutations of the common p53 mutants | Q33281483 | ||
| The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53. | Q33781484 | ||
| The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2. | Q33889383 | ||
| The regulation of INK4/ARF in cancer and aging | Q34575801 | ||
| E1A signaling to p53 involves the p19(ARF) tumor suppressor | Q35206764 | ||
| Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a. | Q35207550 | ||
| Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF. | Q35208164 | ||
| pRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p16INK4alpha tumor suppressor gene. | Q35565308 | ||
| Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2 | Q36174385 | ||
| Transcriptional regulation by p53: one protein, many possibilities | Q36436698 | ||
| Regulation of the INK4b-ARF-INK4a tumour suppressor locus: all for one or one for all. | Q36572080 | ||
| The oncogenic roles of p53 mutants in mouse models | Q36701574 | ||
| The expanding universe of p53 targets | Q37602507 | ||
| The p53 tumour suppressor gene | Q37751892 | ||
| EZH2-dependent chromatin looping controls INK4a and INK4b, but not ARF, during human progenitor cell differentiation and cellular senescence. | Q39433602 | ||
| TBX3 is overexpressed in breast cancer and represses p14 ARF by interacting with histone deacetylases | Q40017336 | ||
| Oncogenic activity of Cdc6 through repression of the INK4/ARF locus | Q40298342 | ||
| Repression of the Arf tumor suppressor by E2F3 is required for normal cell cycle kinetics | Q40549645 | ||
| Hierarchical recruitment of polycomb group silencing complexes | Q40549661 | ||
| Regulation of the INK4a/ARF locus by histone deacetylase inhibitors | Q46775969 | ||
| P433 | issue | 7 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 2781-2792 | |
| P577 | publication date | 2011-03-29 | |
| P1433 | published in | Cancer Research | Q326097 |
| P1476 | title | p53 binds to and is required for the repression of Arf tumor suppressor by HDAC and polycomb | |
| P478 | volume | 71 |
| Q34148155 | ARF and p53 coordinate tumor suppression of an oncogenic IFN-β-STAT1-ISG15 signaling axis. |
| Q42143482 | ARF inhibits the growth and malignant progression of non-small-cell lung carcinoma. |
| Q38172135 | Aberrant epigenetic regulators control expansion of human CD34+ hematopoietic stem/progenitor cells |
| Q37344073 | Differential effects on ARF stability by normal versus oncogenic levels of c-Myc expression |
| Q42367900 | Enhancing chemotherapy sensitivity by targeting PcG via the ATM/p53 pathway |
| Q35236773 | Epigenetic changes in the CDKN2A locus are associated with differential expression of P16INK4A and P14ARF in HPV-positive oropharyngeal squamous cell carcinoma |
| Q39126232 | Functional interplay between the DNA-damage-response kinase ATM and ARF tumour suppressor protein in human cancer |
| Q34984471 | GFI1 is repressed by p53 and inhibits DNA damage-induced apoptosis |
| Q37583458 | Human Kruppel-related 3 (HKR3) is a novel transcription activator of alternate reading frame (ARF) gene |
| Q92689602 | Identification of De Novo Enhancers Activated by TGFβ to Drive Expression of CDKN2A and B in HeLa Cells |
| Q90701972 | Loss of p53 function at late stages of tumorigenesis confers ARF-dependent vulnerability to p53 reactivation therapy |
| Q36157946 | Mechanisms of Yin Yang 1 in oncogenesis: the importance of indirect effects |
| Q36395599 | Mutational profile and prognostic significance of TP53 in diffuse large B-cell lymphoma patients treated with R-CHOP: report from an International DLBCL Rituximab-CHOP Consortium Program Study |
| Q39405071 | RUVBL2 is a novel repressor of ARF transcription |
| Q38199695 | Role of Ink4a/Arf locus in beta cell mass expansion under physiological and pathological conditions |
| Q39184995 | Siva1 inhibits p53 function by acting as an ARF E3 ubiquitin ligase. |
| Q24273295 | The transcription factor p53: not a repressor, solely an activator |
| Q34989369 | Wild type p53 transcriptionally represses the SALL2 transcription factor under genotoxic stress |
| Q37708974 | p16INK4a suppresses BRCA1-deficient mammary tumorigenesis |
| Q43249196 | p53 restoration kills primitive leukemia cells in vivo and increases survival of leukemic mice. |
| Q33794127 | p53-dependent gene repression through p21 is mediated by recruitment of E2F4 repression complexes |
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