review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Norman Sharpless | Q21260355 |
P2093 | author name string | William Y Kim | |
P2860 | cites work | Oncogenic activity of Cdc6 through repression of the INK4/ARF locus | Q40298342 |
Induction of DNA methylation and gene silencing by short interfering RNAs in human cells | Q40525501 | ||
Tumour biology: senescence in premalignant tumours | Q42802962 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 265-275 | |
P577 | publication date | 2006-10-01 | |
P1433 | published in | Cell | Q655814 |
P1476 | title | The regulation of INK4/ARF in cancer and aging | |
P478 | volume | 127 |
Q84583331 | 20 years studying p53 functions in genetically engineered mice |
Q29614875 | A HapMap harvest of insights into the genetics of common disease |
Q28117127 | A KRAS-directed transcriptional silencing pathway that mediates the CpG island methylator phenotype |
Q40066538 | A Role for Cellular Senescence in Birth Timing |
Q38756663 | A Structural Perspective on Readout of Epigenetic Histone and DNA Methylation Marks |
Q37446339 | A common variant at 9p21 is associated with sudden and arrhythmic cardiac death |
Q34816288 | A common variant in the CDKN2B gene on chromosome 9p21 protects against coronary artery disease in Americans of African ancestry. |
Q36136695 | A common variant of the p16(INK4a) genetic region is associated with physical function in older people |
Q37644812 | A common variant within the HNF1B gene is associated with overall survival of multiple myeloma patients: results from the IMMEnSE consortium and meta-analysis. |
Q29547210 | A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants |
Q35741860 | A novel approach for determining cancer genomic breakpoints in the presence of normal DNA |
Q28506253 | A novel zinc finger protein Zfp277 mediates transcriptional repression of the Ink4a/arf locus through polycomb repressive complex 1 |
Q35273882 | A pathway for the control of anoikis sensitivity by E-cadherin and epithelial-to-mesenchymal transition |
Q37377247 | A quantitative model for age-dependent expression of the p16INK4a tumor suppressor |
Q35126643 | A screen identifies the oncogenic micro-RNA miR-378a-5p as a negative regulator of oncogene-induced senescence |
Q35626799 | A seven-gene CpG-island methylation panel predicts breast cancer progression |
Q33310467 | AGEMAP: a gene expression database for aging in mice |
Q38853225 | AMPK and HIF signaling pathways regulate both longevity and cancer growth: the good news and the bad news about survival mechanisms |
Q33715768 | ANRIL Promoter DNA Methylation: A Perinatal Marker for Later Adiposity |
Q28394102 | ANRIL: molecular mechanisms and implications in human health |
Q42585576 | AP4 directly downregulates p16 and p21 to suppress senescence and mediate transformation |
Q39132153 | ARF regulates the stability of p16 protein via REGγ-dependent proteasome degradation. |
Q61801116 | Aberrant Expression of p14 in Human Cancers: A New Biomarker? |
Q59358004 | Aberrant expression of p16 in human cancers - a new biomarker? |
Q35574809 | Ablation of the p16(INK4a) tumour suppressor reverses ageing phenotypes of klotho mice |
Q36866479 | Activation of PPARγ/P53 signaling is required for curcumin to induce hepatic stellate cell senescence |
Q39807622 | Activation of p53 by Nutlin-3a, an antagonist of MDM2, induces apoptosis and cellular senescence in adult T-cell leukemia cells |
Q64264854 | Adult Cardiac Stem Cell Aging: A Reversible Stochastic Phenomenon? |
Q34948525 | Age-dependent decline in beta-cell proliferation restricts the capacity of beta-cell regeneration in mice |
Q36995395 | Aging and cancer resistance in lymphoid progenitors are linked processes conferred by p16Ink4a and Arf. |
Q38114939 | Aging and neurogenesis in the adult forebrain: what we have learned and where we should go from here |
Q37122443 | Aging stem cells, latexin, and longevity |
Q34199776 | Aging, cellular senescence, and cancer |
Q50002288 | Alteration of Epigenetic Regulation by Long Noncoding RNAs in Cancer. |
Q33916962 | Alterations in RD(INK4/ARF) -mediated en bloc regulation of the INK4-ARF locus in human squamous cell carcinoma of the head and neck. |
Q30479111 | Alterations in mitosis and cell cycle progression caused by a mutant lamin A known to accelerate human aging |
Q44029916 | Alterations in the tumor suppressor gene p16(INK4A) are associated with aggressive behavior of penile carcinomas |
Q53359204 | Alterations of the cell-cycle inhibitors p27(KIP1) and p16(INK4a) are frequent in blastic plasmacytoid dendritic cell neoplasms. |
Q57025486 | An EBNA3C-deleted Epstein-Barr virus (EBV) mutant causes B-cell lymphomas with delayed onset in a cord blood-humanized mouse model |
Q57163370 | An Update on the Clinical Use of CDK4/6 Inhibitors in Breast Cancer |
Q38515827 | An overview of new biomolecular pathways in pathogen-related cancers |
Q33732034 | Analysis of side population cells derived from dental pulp tissue |
Q36845050 | Animal models of GWAS-identified type 2 diabetes genes |
Q41101214 | Anticancer Effects of Sinocrassulosides VI/VII from Silene viscidula on HeLa Cells. |
Q36712752 | Arf tumor suppressor and miR-205 regulate cell adhesion and formation of extraembryonic endoderm from pluripotent stem cells |
Q39386624 | Arp2/3 is critical for lamellipodia and response to extracellular matrix cues but is dispensable for chemotaxis |
Q33488692 | Assessment of the effect of betaine on p16 and c-myc DNA methylation and mRNA expression in a chemical induced rat liver cancer model |
Q46259294 | Association between polymorphisms in SLC30A8, HHEX, CDKN2A/B, IGF2BP2, FTO, WFS1, CDKAL1, KCNQ1 and type 2 diabetes in the Korean population. |
Q44744535 | Association between the rs1333040 polymorphism on the chromosomal 9p21 locus and sporadic brain arteriovenous malformations |
Q43486091 | Association between type 2 diabetes and CDKN2A/B: a meta-analysis study |
Q46937493 | Association between type 2 diabetes and rs10811661 polymorphism upstream of CDKN2A/B: a meta-analysis |
Q36145408 | Attenuation of p38α MAPK stress response signaling delays the in vivo aging of skeletal muscle myofibers and progenitor cells |
Q26865873 | Axis of ageing: telomeres, p53 and mitochondria |
Q28251851 | BIS targeting induces cellular senescence through the regulation of 14-3-3 zeta/STAT3/SKP2/p27 in glioblastoma cells |
Q64054793 | Bcl-x inhibition enhances Dinaciclib-induced cell death in soft-tissue sarcomas |
Q40033702 | Beyond heterochromatin: SIR2 inhibits the initiation of DNA replication |
Q53765766 | Biallelic loss of CDKN2A is associated with poor response to treatment in pediatric acute lymphoblastic leukemia. |
Q36374862 | Bim dictates naive CD4 T cell lifespan and the development of age-associated functional defects |
Q35894352 | Biological, clinical, and psychosocial correlates at the interface of cancer and aging research |
Q61471520 | Bmi-1 Reduction Plays a Key Role in Physiological and Premature Aging of Primary Human Keratinocytes |
Q37175990 | Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation |
Q36121000 | Bmi-1: At the crossroads of physiological and pathological biology |
Q35040426 | Branched-chain amino acids enhance premature senescence through mammalian target of rapamycin complex I-mediated upregulation of p21 protein |
Q38089482 | Breathing-in epigenetic change with vitamin C. |
Q35063674 | Bridging the gap between single molecule and ensemble methods for measuring lateral dynamics in the plasma membrane |
Q38831684 | CBX7 and miR-9 are part of an autoregulatory loop controlling p16(INK) (4a). |
Q28259261 | CDC6: from DNA replication to cell cycle checkpoints and oncogenesis |
Q47658848 | CDK4/6 blockade in breast cancer: current experience and future perspectives |
Q47108489 | CDKN2A and CDKN2B methylation in coronary heart disease cases and controls |
Q50064021 | CDKN2A/B T2D GWAS Risk-SNPs Impact Locus Gene Expression and Proliferation in Human Islets. |
Q36957037 | Calorie restriction-induced SIRT6 activation delays aging by suppressing NF-κB signaling |
Q33774265 | Cdc6 contributes to abrogating the G1 checkpoint under hypoxic conditions in HPV E7 expressing cells |
Q37457876 | Cdc6 contributes to cisplatin-resistance by activation of ATR-Chk1 pathway in bladder cancer cells |
Q38024606 | Cdc6: a multi-functional molecular switch with critical role in carcinogenesis |
Q37192078 | Cdk2 and Cdk4 activities are dispensable for tumorigenesis caused by the loss of p53. |
Q35952700 | Cdkn2a is an atherosclerosis modifier locus that regulates monocyte/macrophage proliferation. |
Q50959563 | Cell-Cycle Therapeutics Come of Age. |
Q35815320 | Cellular senescence and organismal aging |
Q24629853 | Cellular senescence and tumor suppressor gene p16 |
Q100525978 | Cellular senescence-mediated exacerbation of Duchenne muscular dystrophy |
Q64272067 | Cellular senescence: a promising strategy for cancer therapy |
Q34041305 | Cellular senescence: from physiology to pathology |
Q29615561 | Cellular senescence: when bad things happen to good cells |
Q33588661 | Chromatin modifications: the driving force of senescence and aging? |
Q21092443 | Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression |
Q38151211 | Chromosome 9p21 primary open-angle glaucoma susceptibility locus: a review. |
Q24602703 | Chromosome 9p21 variant predicts mortality after coronary artery bypass graft surgery |
Q96126190 | Chronic expression of p16INK4a in the epidermis induces Wnt-mediated hyperplasia and promotes tumor initiation |
Q34631354 | Chronic myeloid leukaemia as a model of disease evolution in human cancer |
Q28252088 | Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders |
Q38103829 | Clinical significance of cell cycle inhibitors in hepatocellular carcinoma |
Q35051842 | Clonal heterogeneity of lymphoid malignancies correlates with poor prognosis |
Q37259249 | Combined modulation of polycomb and trithorax genes rejuvenates β cell replication |
Q26864051 | Common features of chromatin in aging and cancer: cause or coincidence? |
Q33559062 | Common genetic variants on chromosome 9p21 are associated with myocardial infarction and type 2 diabetes in an Italian population |
Q33618526 | Common genetic variants on chromosome 9p21 predict perioperative myocardial injury after coronary artery bypass graft surgery |
Q34335898 | Common variants on chromosome 9p21 are associated with normal tension glaucoma |
Q34162527 | Constant p53 pathway inactivation in a large series of soft tissue sarcomas with complex genetics |
Q34280071 | Coordinated expression of cyclin-dependent kinase-4 and its regulators in human oral tumors |
Q88770220 | Copy number abnormality of acute lymphoblastic leukemia cell lines based on their genetic subtypes |
Q39956460 | Critical and distinct roles of p16 and telomerase in regulating the proliferative life span of normal human prostate epithelial progenitor cells. |
Q38852912 | Cultured myoblasts from patients affected by myotonic dystrophy type 2 exhibit senescence-related features: ultrastructural evidence |
Q36050025 | Cyclin-dependent kinase-mediated Sox2 phosphorylation enhances the ability of Sox2 to establish the pluripotent state |
Q42381521 | Cytokine-dependent imatinib resistance in mouse BCR-ABL+, Arf-null lymphoblastic leukemia |
Q42109237 | DDB1-CUL4 and MLL1 mediate oncogene-induced p16INK4a activation |
Q28116426 | DISP3 promotes proliferation and delays differentiation of neural progenitor cells |
Q26746962 | DNA Damage: A Main Determinant of Vascular Aging |
Q36360646 | DNA damage, cellular senescence and organismal ageing: causal or correlative? |
Q37365439 | DNA methylation, a hand behind neurodegenerative diseases |
Q34720959 | DNA replication stress, genome instability and aging |
Q39584394 | DUSP13B/TMDP inhibits stress-activated MAPKs and suppresses AP-1-dependent gene expression |
Q41030507 | Decreased long noncoding RNA MIR31HG is correlated with poor prognosis and contributes to cell proliferation in gastric cancer |
Q39910409 | Defining the cooperative genetic changes that temporally drive alveolar rhabdomyosarcoma |
Q28389491 | Defining the toxicology of aging |
Q33975692 | Deletion analysis of BMI1 oncoprotein identifies its negative regulatory domain |
Q33737795 | Detection, analysis and clinical validation of chromosomal aberrations by multiplex ligation-dependent probe amplification in chronic leukemia |
Q37833005 | Development of molecularly targeted therapies in biliary tract cancers: reassessing the challenges and opportunities |
Q41548915 | Development of zebrafish medulloblastoma-like PNET model by TALEN-mediated somatic gene inactivation |
Q36898198 | Different Roles of Negative and Positive Components of the Circadian Clock in Oncogene-induced Neoplastic Transformation |
Q49227483 | Differential expression of cyclin D1, Ki‑67, pRb, and p53 in psoriatic skin lesions and normal skin. |
Q34085053 | Differential p53-independent outcomes of p19(Arf) loss in oncogenesis |
Q35873154 | Differentially Expressed Genes and Signature Pathways of Human Prostate Cancer |
Q64114450 | Disease-Associated SNPs in Inflammation-Related lncRNAs |
Q45868901 | Disease-associated polymorphisms in 9p21 are not associated with extreme longevity |
Q41767409 | Dissecting the Roles of Polycomb Repressive Complex 2 Subunits in the Control of Skin Development. |
Q36143489 | Dmp1 and tumor suppression |
Q42246401 | Dmp1 physically interacts with p53 and positively regulates p53's stability, nuclear localization, and function |
Q38929207 | Downregulation of Kruppel-like factor 2 is associated with poor prognosis for nonsmall-cell lung cancer |
Q38910285 | Downregulation of TPTE2P1 Inhibits Migration and Invasion of Gallbladder Cancer Cells |
Q36387594 | Dual Roles of MDM2 in the Regulation of p53: Ubiquitination Dependent and Ubiquitination Independent Mechanisms of MDM2 Repression of p53 Activity |
Q36949451 | Dual roles of telomere dysfunction in initiation and suppression of tumorigenesis |
Q34047232 | Dynamics of ARF regulation that control senescence and cancer |
Q53608328 | Dysfunction of liver regeneration in aged liver after partial hepatectomy. |
Q47106948 | Dysregulation of YAP by ARF Stimulated with Tea-derived Carbon Nanodots |
Q35102302 | E4F1 deficiency results in oxidative stress-mediated cell death of leukemic cells |
Q38156169 | EBV finds a polycomb-mediated, epigenetic solution to the problem of oncogenic stress responses triggered by infection |
Q43109424 | ELF4/MEF activates MDM2 expression and blocks oncogene-induced p16 activation to promote transformation |
Q39433602 | EZH2-dependent chromatin looping controls INK4a and INK4b, but not ARF, during human progenitor cell differentiation and cellular senescence. |
Q36079202 | Early G₁ cyclin-dependent kinases as prognostic markers and potential therapeutic targets in esophageal adenocarcinoma. |
Q27002577 | Emerging epigenetic mechanisms of long non-coding RNAs |
Q37784425 | Empowering self-renewal and differentiation: the role of mitochondria in stem cells |
Q36102464 | Epidemiology and genetics of sudden cardiac death |
Q34213023 | Epigenetic antagonism between polycomb and SWI/SNF complexes during oncogenic transformation |
Q80136830 | Epigenetic changes in tumor suppressor genes, P15, P16, APC-3 and E-cadherin in body fluid |
Q39662058 | Epigenetic inactivation of T-box transcription factor 5, a novel tumor suppressor gene, is associated with colon cancer. |
Q83829640 | Epigenetic mechanisms in Alzheimer's disease |
Q37007058 | Epigenetic mechanisms in penile carcinoma |
Q24604190 | Epigenetic regulation of the INK4b-ARF-INK4a locus: in sickness and in health |
Q37297042 | Epigenetic silencing of the p16(INK4a) tumor suppressor is associated with loss of CTCF binding and a chromatin boundary |
Q37841191 | Epigenetic silencing of tumor suppressor genes in pancreatic cancer |
Q34391404 | Epigenetics across the human lifespan |
Q92759502 | Epigenetics of human diseases and scope in future therapeutics |
Q34549944 | Epstein-Barr virus nuclear antigens 3C and 3A maintain lymphoblastoid cell growth by repressing p16INK4A and p14ARF expression |
Q89659960 | Establishment of a Temperature-Sensitive Model of Oncogene-Induced Senescence in Angiosarcoma Cells |
Q34403436 | Establishment of a new human pleomorphic malignant fibrous histiocytoma cell line, FU-MFH-2: molecular cytogenetic characterization by multicolor fluorescence in situ hybridization and comparative genomic hybridization |
Q26769654 | Expanding Horizons for Abdominal Aortic Aneurysms |
Q21202791 | Explaining oscillations and variability in the p53-Mdm2 system |
Q34180117 | Exploiting tumor cell senescence in anticancer therapy |
Q35894500 | Expression of cdk4 and p16 in Oral Lichen Planus |
Q30433884 | Expression of linear and novel circular forms of an INK4/ARF-associated non-coding RNA correlates with atherosclerosis risk. |
Q36224261 | Expression of p14(ARF), p15(INK4b), p16(INK4a) and skp2 increases during esophageal squamous cell cancer progression |
Q37004455 | Expression of p14ARF, MDM2, and MDM4 in human retinoblastoma |
Q89219396 | Expression of p16 and SATB1 in Invasive Ductal Breast Cancer - A Preliminary Study |
Q39860968 | Expression of p16 in lymph node metastases of adjuvantly treated stage III colorectal cancer patients identifies poor prognostic subgroups: a retrospective analysis of biomarkers in matched primary tumor and lymph node metastases |
Q24646862 | Expression of p16(INK4a) in peripheral blood T-cells is a biomarker of human aging |
Q42020365 | Expression of the Arf tumor suppressor gene is controlled by Tgfbeta2 during development |
Q37308341 | Expression of the senescence marker p16INK4a in skin biopsies of acute lymphoblastic leukemia survivors: a pilot study |
Q28589370 | Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells |
Q60300338 | Ezh2 programs T differentiation by integrating phosphorylation-dependent activation of Bcl6 and polycomb-dependent repression of p19Arf |
Q37730642 | FOXP1 controls mesenchymal stem cell commitment and senescence during skeletal aging |
Q37319942 | Failure of CDKN2A/B (INK4A/B-ARF)-mediated tumor suppression and resistance to targeted therapy in acute lymphoblastic leukemia induced by BCR-ABL. |
Q24317761 | Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development |
Q38536371 | Forging a signature of in vivo senescence |
Q54712822 | Frequent deletion of CDKN2A and recurrent coamplification of KIT, PDGFRA, and KDR in fibrosarcoma of bone--an array comparative genomic hybridization study. |
Q89510331 | From Genetic Alterations to Tumor Microenvironment: The Ariadne's String in Pancreatic Cancer |
Q38134247 | From genotype to phenotype in human atherosclerosis--recent findings |
Q26998944 | Functional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis |
Q39126232 | Functional interplay between the DNA-damage-response kinase ATM and ARF tumour suppressor protein in human cancer |
Q28567479 | Gene expression profiling suggests a pathological role of human bone marrow-derived mesenchymal stem cells in aging-related skeletal diseases |
Q38562707 | Gene expression signature of c-MYC-immortalized human fibroblasts reveals loss of growth inhibitory response to TGFβ. |
Q36283428 | Gene regulatory network underlying the immortalization of epithelial cells |
Q41410958 | Genetic alterations of RD(INK4/ARF) enhancer in human cancer cells |
Q33577610 | Genetic analysis of six SNPs in candidate genes associated with high cross-race risk of development of thoracic aortic aneurysms and dissections in Chinese Han population |
Q37025333 | Genetic and epigenetic alterations in breast cancer: what are the perspectives for clinical practice? |
Q34630956 | Genetic evolution of pancreatic cancer: lessons learnt from the pancreatic cancer genome sequencing project |
Q37864570 | Genetic mechanisms mediating atherosclerosis susceptibility at the chromosome 9p21 locus |
Q36670266 | Genetic suppression reveals DNA repair-independent antagonism between BRCA1 and COBRA1 in mammary gland development. |
Q37765099 | Genetics of biliary tract cancers and emerging targeted therapies |
Q24313142 | Genome analysis identifies the p15ink4b tumor suppressor as a direct target of the ZNF217/CoREST complex |
Q35871482 | Genome-Wide Scan Informed by Age-Related Disease Identifies Loci for Exceptional Human Longevity |
Q34218772 | Genome-wide association study of coronary artery disease |
Q81303887 | Genome-wide association study of susceptibility alleles for coronary artery disease |
Q37445062 | Genome-wide expression profiling reveals transcriptomic variation and perturbed gene networks in androgen-dependent and androgen-independent prostate cancer cells. |
Q47171855 | Germline hemizygous deletion of CDKN2A-CDKN2B locus in a patient presenting with Li-Fraumeni syndrome. |
Q37349463 | Ginsenoside Rh2-mediated G1 phase cell cycle arrest in human breast cancer cells is caused by p15 Ink4B and p27 Kip1-dependent inhibition of cyclin-dependent kinases |
Q36149209 | Global heterochromatin loss: a unifying theory of aging? |
Q39761800 | Glucose restriction can extend normal cell lifespan and impair precancerous cell growth through epigenetic control of hTERT and p16 expression |
Q33897945 | H3K27 trimethylation is an early epigenetic event of p16INK4a silencing for regaining tumorigenesis in fusion reprogrammed hepatoma cells |
Q90576953 | HKR3 regulates cell cycle through the inhibition of hTERT in hepatocellular carcinoma cell lines |
Q43159115 | Heme oxygenase-1/p21WAF1 mediates peroxisome proliferator-activated receptor-gamma signaling inhibition of proliferation of rat pulmonary artery smooth muscle cells |
Q34784941 | Heterogeneous activation of p19Arf in pulmonary artery smooth muscle cells |
Q54603571 | High-resolution array CGH identifies common mechanisms that drive embryonal rhabdomyosarcoma pathogenesis. |
Q34362603 | Higher incidence of death in multi-vessel coronary artery disease patients associated with polymorphisms in chromosome 9p21. |
Q28264875 | Histone H3.3 maintains genome integrity during mammalian development |
Q38219897 | Histone demethylase Jumonji D3 (JMJD3/KDM6B) at the nexus of epigenetic regulation of inflammation and the aging process |
Q90164343 | How Cancer Exploits Ribosomal RNA Biogenesis: A Journey beyond the Boundaries of rRNA Transcription |
Q34667132 | How stem cells age and why this makes us grow old. |
Q39579087 | How to measure RNA expression in rare senescent cells expressing any specific protein such as p16Ink4a |
Q37583458 | Human Kruppel-related 3 (HKR3) is a novel transcription activator of alternate reading frame (ARF) gene |
Q40135907 | Human p16gamma, a novel transcriptional variant of p16(INK4A), coexpresses with p16(INK4A) in cancer cells and inhibits cell-cycle progression. |
Q51530435 | Hydroxytyrosol inhibits growth and cell proliferation and promotes high expression of sfrp4 in rat mammary tumours. |
Q46094682 | Hypermethylation of P15, P16, and E-cadherin genes in ovarian cancer |
Q39740254 | IKKbeta specifically binds to P16 and phosphorylates Ser8 of P16. |
Q50903003 | IL-4 induces a suppressive IL-10-producing CD8+ T cell population via a Cdkn2a-dependent mechanism. |
Q34042900 | INK4 locus of the tumor-resistant rodent, the naked mole rat, expresses a functional p15/p16 hybrid isoform |
Q21562488 | INK4/ARF transcript expression is associated with chromosome 9p21 variants linked to atherosclerosis |
Q34426276 | INK4a knockout mice exhibit increased fibrosis under normal conditions and in response to unilateral ureteral obstruction |
Q37017649 | INK4a/ARF limits the expansion of cells suffering from replication stress |
Q42149145 | INK4a/ARF-dependent senescence upon persistent replication stress |
Q92689602 | Identification of De Novo Enhancers Activated by TGFβ to Drive Expression of CDKN2A and B in HeLa Cells |
Q54095573 | Identification of differentially expressed circular RNAs during TGF-ß1-induced endothelial-to-mesenchymal transition in rat coronary artery endothelial cells. |
Q37636652 | Identification of genetic variants predictive of early onset pancreatic cancer through a population science analysis of functional genomic datasets |
Q36976234 | Impact of aging on the biology of breast cancer |
Q41681138 | Inactivation of p15INK4b in chronic arsenic poisoning cases |
Q42806820 | Increase in tumor suppressor Arf compensates gene dysregulation in in vitro aged adipocytes |
Q36755214 | Inducible re-expression of p16 in an orthotopic mouse model of pancreatic cancer inhibits lymphangiogenesis and lymphatic metastasis |
Q42775668 | Induction of Therapeutic Senescence in Vemurafenib-Resistant Melanoma by Extended Inhibition of CDK4/6 |
Q31111648 | Induction of p16(INK4a) is the major barrier to proliferation when Epstein-Barr virus (EBV) transforms primary B cells into lymphoblastoid cell lines |
Q36820720 | Inhibition of TGF-β Signaling Promotes Human Pancreatic β-Cell Replication. |
Q54115156 | Inhibition of p16INK4A to Rejuvenate Aging Human Cardiac Progenitor Cells via the Upregulation of Anti-oxidant and NFκB Signal Pathways. |
Q42153635 | Ink4-Arf locus in cancer and aging |
Q39042581 | Integrative DNA methylation and gene expression analysis in high-grade soft tissue sarcomas |
Q44285666 | Inverse association of p16 INK4a and p14 ARF methylation of the CDKN2a locus in different Gleason scores of prostate cancer |
Q30251397 | Islet biology, the CDKN2A/B locus and type 2 diabetes risk |
Q98779115 | Lamivudine Inhibits Alu RNA-induced Retinal Pigment Epithelium Degeneration via Anti-inflammatory and Anti-senescence Activities |
Q37164562 | Large CTG repeats trigger p16-dependent premature senescence in myotonic dystrophy type 1 muscle precursor cells |
Q33424968 | Large scale genotyping study for asthma in the Japanese population |
Q36660711 | Lentiviral vector-based insertional mutagenesis identifies genes associated with liver cancer |
Q97635157 | Leveraging innovative therapies with an evolving understanding of the molecular pathogenesis of penile squamous cell carcinoma |
Q28277689 | Linking functional decline of telomeres, mitochondria and stem cells during ageing |
Q28550609 | Liver Sinusoidal Endothelial Cells Escape Senescence by Loss of p19ARF |
Q90154670 | LncRNA GUARDIN suppresses cellular senescence through a LRP130-PGC1α-FOXO4-p21-dependent signaling axis |
Q35769198 | Long Term Exposure to Polyphenols of Artichoke (Cynara scolymus L.) Exerts Induction of Senescence Driven Growth Arrest in the MDA-MB231 Human Breast Cancer Cell Line |
Q24632383 | Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene |
Q36790436 | Long non-coding RNA in cancer |
Q37249139 | Long non-coding RNAs: novel targets for nervous system disease diagnosis and therapy |
Q36519018 | Long-lived cancer-resistant rodents as new model species for cancer research |
Q33909576 | Loss of DIP2C in RKO cells stimulates changes in DNA methylation and epithelial-mesenchymal transition |
Q37222774 | Loss of heterozygosity (LOH) profiles--validated risk predictors for progression to oral cancer |
Q34180263 | Loss of p15/Ink4b accompanies tumorigenesis triggered by complex DNA double-strand breaks. |
Q41348802 | Loss of p16INK4A stimulates aberrant mitochondrial biogenesis through a CDK4/Rb-independent pathway |
Q37133940 | Loss of p53 induces tumorigenesis in p21-deficient mesenchymal stem cells |
Q40859822 | MMP7 interacts with ARF in nucleus to potentiate tumor microenvironments for prostate cancer progression in vivo. |
Q34504863 | MUC1 oncoprotein suppresses activation of the ARF-MDM2-p53 pathway |
Q64061957 | MYC Oncogene Contributions to Release of Cell Cycle Brakes |
Q33804675 | MYC activation cooperates with Vhl and Ink4a/Arf loss to induce clear cell renal cell carcinoma. |
Q57036262 | MYC-driven malignant transformation of mature murine B cells requires inhibition of both intrinsic apoptosis and p53 activity |
Q38077437 | Maintenance of genomic stability in mouse embryonic stem cells: relevance in aging and disease |
Q40891138 | Mapping of deletion breakpoints at the CDKN2A locus in melanoma: detection of MTAP-ANRIL fusion transcripts |
Q37268813 | Mdm2 deficiency suppresses MYCN-Driven neuroblastoma tumorigenesis in vivo |
Q55002845 | MeCP2-mediated epigenetic regulation in senescent endothelial progenitor cells. |
Q36469676 | Mechanisms underlying the formation of induced pluripotent stem cells |
Q37182019 | Melanomagenesis: overcoming the barrier of melanocyte senescence |
Q44255938 | Meningioma progression in mice triggered by Nf2 and Cdkn2ab inactivation |
Q35072776 | MicroRNA profiling of primary cutaneous large B-cell lymphomas |
Q38244285 | MicroRNAs and p63 in epithelial stemness. |
Q90455403 | Microarray gene expression profiling in colorectal (HCT116) and hepatocellular (HepG2) carcinoma cell lines treated with Melicope ptelefolia leaf extract reveals transcriptome profiles exhibiting anticancer activity |
Q35799801 | Mitochondrial oxidative stress caused by Sod2 deficiency promotes cellular senescence and aging phenotypes in the skin |
Q34356281 | Mixture models and wavelet transforms reveal high confidence RNA-protein interaction sites in MOV10 PAR-CLIP data |
Q42777312 | Modeling Glaucoma: Retinal Ganglion Cells Generated from Induced Pluripotent Stem Cells of Patients with SIX6 Risk Allele Show Developmental Abnormalities. |
Q89983824 | Modeling clear cell renal cell carcinoma and therapeutic implications |
Q64259183 | Molecular Mechanisms of Neurogenic Aging in the Adult Mouse Subventricular Zone |
Q33912955 | Molecular cytogenetic characterization of canine histiocytic sarcoma: A spontaneous model for human histiocytic cancer identifies deletion of tumor suppressor genes and highlights influence of genetic background on tumor behavior |
Q37536877 | Molecular driver alterations and their clinical relevance in cancer of unknown primary site |
Q33432840 | Molecular evidence of senescence in corneal endothelial cells of senescence-accelerated mice |
Q34640467 | Molecular pathways in pancreatic carcinogenesis |
Q41869395 | Molecular profiling reveals primary mesothelioma cell lines recapitulate human disease. |
Q40067775 | Mutually exclusive inactivation of DMP1 and ARF/p53 in lung cancer |
Q36631828 | N-ethyl-N-nitrosourea (ENU)-induced meningiomatosis and meningioma in p16(INK4a)/p19(ARF) tumor suppressor gene-deficient mice |
Q35674471 | Naive T cell maintenance and function in human aging |
Q40546752 | Nevus senescence. |
Q24615109 | New common variants affecting susceptibility to basal cell carcinoma |
Q21261481 | Non-coding RNA ANRIL and the number of plexiform neurofibromas in patients with NF1 microdeletions |
Q35881657 | Non-coding RNAs: key regulators of mammalian transcription |
Q36866357 | Noncytotoxic differentiation treatment of renal cell cancer |
Q48251118 | Novel endogenous simian retroviral integrations in Vero cells: implications for quality control of a human vaccine cell substrate |
Q39307999 | Novel frameshift mutation in the p16/INK4A tumor suppressor gene in canine breast cancer alters expression from the p16/INK4A/p14ARF locus |
Q90647910 | Nuclear MET requires ARF and is inhibited by carbon nanodots through binding to phospho-tyrosine in prostate cancer |
Q42032252 | Nuclear receptor NR5A2 controls neural stem cell fate decisions during development. |
Q55365177 | OCT4B regulates p53 and p16 pathway genes to prevent apoptosis of breast cancer cells. |
Q40885761 | Oncogene-induced senescence underlies the mutual exclusive nature of oncogenic KRAS and BRAF. |
Q36996311 | Opposing roles for p16Ink4a and p19Arf in senescence and ageing caused by BubR1 insufficiency |
Q53514634 | Overexpression of p27kip1 in urinary bladder urothelial carcinoma. |
Q28586356 | PAC1 gene knockout reveals an essential role of chaperone-mediated 20S proteasome biogenesis and latent 20S proteasomes in cellular homeostasis |
Q38904824 | Pancreatic cancer biology and genetics from an evolutionary perspective |
Q42252640 | Paradoxical down-regulation of p16 mRNA with advancing age in acute myeloid leukemia |
Q33941999 | Pathway landscapes and epigenetic regulation in breast cancer and melanoma cell lines. |
Q52724204 | Performance of the UroVysion® FISH assay for the diagnosis of malignant effusions using two cutoff strategies. |
Q36350009 | Perinatal DNA Methylation at CDKN2A Is Associated With Offspring Bone Mass: Findings From the Southampton Women's Survey. |
Q34031075 | Perspectives of Long Non-Coding RNAs in Cancer Diagnostics |
Q39139826 | Phenotype-independent effects of retroviral transduction in human dental pulp stem cells. |
Q30572259 | Polycomb group gene BMI1 controls invasion of medulloblastoma cells and inhibits BMP-regulated cell adhesion |
Q37629613 | Polycomb group protein gene silencing, non-coding RNA, stem cells, and cancer |
Q37869366 | Polycomb group proteins in hematopoietic stem cell aging and malignancies |
Q37175962 | Polycomb protein Ezh2 regulates pancreatic beta-cell Ink4a/Arf expression and regeneration in diabetes mellitus. |
Q37718268 | Polycomb proteins control proliferation and transformation independently of cell cycle checkpoints by regulating DNA replication |
Q38069050 | Polycomb-group proteins in hematopoietic stem cell regulation and hematopoietic neoplasms |
Q46006380 | Polymorphism in ANRIL is associated with relapse in patients with multiple myeloma after autologous stem cell transplant. |
Q36973723 | Potassium channel activation inhibits proliferation of breast cancer cells by activating a senescence program |
Q38119789 | Premature lung aging and cellular senescence in the pathogenesis of idiopathic pulmonary fibrosis and COPD/emphysema |
Q24607181 | Pro-tumorigenic effects of miR-31 loss in mesothelioma |
Q34127512 | Progeria syndromes and ageing: what is the connection? |
Q90529098 | Promoter methylation analysis of CDH1 and p14ARF genes in patients with urothelial bladder cancer |
Q24298437 | Proteomic analysis of p16ink4a-binding proteins |
Q39395750 | Quantitative assessment of higher-order chromatin structure of the INK4/ARF locus in human senescent cells |
Q36785987 | Quantitative methylation analyses of resection margins predict local recurrences and disease-specific deaths in patients with head and neck squamous cell carcinomas |
Q37602305 | RAS in cellular transformation and senescence |
Q39293634 | RING1B ubiquitination and stability are regulated by ARF. |
Q38906940 | RNA interference of Biot2 induces G1 phase arrest and apoptosis in mouse colorectal cancer cell line |
Q40144689 | RNA polymerase III transcription is repressed in response to the tumour suppressor ARF. |
Q39368650 | RNA processing as an alternative route to attack glioblastoma. |
Q57085790 | RNA processing is altered in skeletal muscle nuclei of patients affected by myotonic dystrophy |
Q39168515 | Radiation-induced cellular senescence results from a slippage of long-term G2 arrested cells into G1 phase |
Q24682671 | Rapid asymmetric evolution of a dual-coding tumor suppressor INK4a/ARF locus contradicts its function |
Q43877274 | Ras signaling is essential for skin development. |
Q37309123 | Real-time in vivo imaging of p16Ink4a reveals cross talk with p53. |
Q42917409 | Real-time in vivo imaging of p16gene expression: a new approach to study senescence stress signaling in living animals |
Q37310063 | Recent insights into the molecular mechanisms involved in aging and the malignant transformation of adult stem/progenitor cells and their therapeutic implications |
Q33274149 | Recurrent chromosomal copy number alterations in sporadic chordomas |
Q34665706 | Regulation of senescence in cancer and aging |
Q52582577 | Regulatory Network of ARF in Cancer Development. |
Q37880852 | Regulatory mechanisms of tumor suppressor P16(INK4A) and their relevance to cancer |
Q38981139 | Rejuvenating Strategies for Stem Cell-Based Therapies in Aging |
Q36611480 | Relationships between stem cell exhaustion, tumour suppression and ageing |
Q37295463 | Repair of senescent myocardium by mesenchymal stem cells is dependent on the age of donor mice |
Q42931458 | Replication stress, a source of epigenetic aberrations in cancer? |
Q37323104 | Replication study of 10 genetic polymorphisms associated with coronary heart disease in a specific high-risk population with familial hypercholesterolemia |
Q37156959 | Replicative stress, stem cells and aging |
Q38728895 | Repression of CDKN2C caused by PML/RARα binding promotes the proliferation and differentiation block in acute promyelocytic leukemia |
Q37149722 | Residues in the alternative reading frame tumor suppressor that influence its stability and p53-independent activities |
Q36766325 | Restricted heterochromatin formation links NFATc2 repressor activity with growth promotion in pancreatic cancer |
Q28535352 | Resveratrol inhibits the growth of gastric cancer by inducing G1 phase arrest and senescence in a Sirt1-dependent manner |
Q39213950 | Reversal of hepatocyte senescence after continuous in vivo cell proliferation |
Q38889012 | Reverse Expression of Aging-Associated Molecules through Transfection of miRNAs to Aged Mice |
Q39693855 | Role for the MOV10 RNA helicase in polycomb-mediated repression of the INK4a tumor suppressor. |
Q37111920 | Role of DMP1 and its future in lung cancer diagnostics |
Q39693770 | Role of DNA methyltransferase 1 in hormone-resistant prostate cancer. |
Q36479612 | Role of senescence marker p16 INK4a measured in peripheral blood T-lymphocytes in predicting length of hospital stay after coronary artery bypass surgery in older adults |
Q51097608 | Runx3 and Cell Fate Decisions in Pancreas Cancer. |
Q39149962 | SATB1 collaborates with loss of p16 in cellular transformation |
Q37820200 | SUMO Losing Balance: SUMO Proteases Disrupt SUMO Homeostasis to Facilitate Cancer Development and Progression |
Q35223877 | Sal-like protein 2 upregulates p16 expression through a proximal promoter element |
Q40284051 | Sav1 Loss Induces Senescence and Stat3 Activation Coinciding with Tubulointerstitial Fibrosis. |
Q48347290 | Senescence and aging: Causes, consequences, and therapeutic avenues |
Q38603571 | Senescence and cancer: An evolving inflammatory paradox |
Q90271850 | Senescence in post-mitotic cells: a driver of ageing? |
Q38072351 | Senescence regulation by the p53 protein family |
Q92937373 | Senescence-associated β-galactosidase activity in the developing avian retina |
Q50745945 | Senescence-related genes possibly responsible for poor liver regeneration after hepatectomy in elderly patients. |
Q30436210 | Sequence variants on chromosome 9p21.3 confer risk for atherosclerotic stroke |
Q35181050 | Signal transduction involving the dmp1 transcription factor and its alteration in human cancer |
Q92892162 | Signaling Pathways Regulating Hematopoietic Stem Cell and Progenitor Aging |
Q54705317 | Simultaneous inhibition of MEK and CDK4 leads to potent apoptosis in human melanoma cells. |
Q39112654 | Simvastatin rises reactive oxygen species levels and induces senescence in human melanoma cells by activation of p53/p21 pathway. |
Q47628821 | Skin differences based on age and chronicity of ultraviolet exposure: results from a gene expression profiling study. |
Q24627126 | Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence |
Q35549516 | Smurf2-mediated ubiquitination and degradation of Id1 regulates p16 expression during senescence |
Q34429099 | Somatic p16(INK4a) loss accelerates melanomagenesis |
Q33828861 | Specific age-associated DNA methylation changes in human dermal fibroblasts |
Q38838490 | Stabilization of the p53-DNA Complex by the Nuclear Protein Dmp1α. |
Q42095359 | Stable form of JAB1 enhances proliferation and maintenance of hematopoietic progenitors |
Q37005066 | Stem cell ageing: does it happen and can we intervene? |
Q42428328 | Structural basis of divergent cyclin-dependent kinase activation by Spy1/RINGO proteins |
Q58762403 | Structural insights into the functional diversity of the CDK-cyclin family |
Q37245042 | Studying chromosome instability in the mouse |
Q58804396 | Systemic Treatment of Advanced Hepatocellular Carcinoma in Older Adults |
Q64122182 | TZAP plays an inhibitory role in the self-renewal of porcine mesenchymal stromal cells and is implicated the regulation of premature senescence via the p53 pathway |
Q28069910 | Targeting the cyclin-dependent kinases (CDK) 4/6 in estrogen receptor-positive breast cancers |
Q90211132 | Telomerase Biology Associations offer Keys to Cancer and Aging Therapeutics |
Q34424261 | Telomere deficiencies on chromosomes 9p, 15p, 15q and Xp: potential biomarkers for breast cancer risk |
Q37171810 | Telomere dysfunction and tumour suppression: the senescence connection |
Q37627017 | Telomeres and telomerase in cancer |
Q57277022 | Telomeres, p21 and the cancer-aging hypothesis |
Q90473411 | Testis-specific Arf promoter expression in a transposase-aided BAC transgenic mouse model |
Q52659598 | The BMI1 polycomb protein represses cyclin G2-induced autophagy to support proliferation in chronic myeloid leukemia cells. |
Q40740405 | The Beginning of the Road for Non-Coding RNAs in Normal Hematopoiesis and Hematologic Malignancies |
Q54561402 | The CDKN2A/CDKN2B/CDK4/CCND1 pathway is pivotal in well-differentiated and dedifferentiated liposarcoma oncogenesis: an analysis of 104 tumors. |
Q37220014 | The DNA damage checkpoint precedes activation of ARF in response to escalating oncogenic stress during tumorigenesis |
Q47132545 | The Dual Role of Cellular Senescence in Developing Tumors and Their Response to Cancer Therapy. |
Q57276930 | The Impact of Aging on Cancer Progression and Treatment |
Q34162817 | The Ink4a/Arf locus is a barrier to direct neuronal transdifferentiation |
Q38184520 | The Mdm network and its regulation of p53 activities: a rheostat of cancer risk |
Q38723756 | The New Immortalized Uroepithelial Cell Line HBLAK Contains Defined Genetic Aberrations Typical of Early Stage Urothelial Tumors. |
Q24680814 | The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells |
Q39454240 | The Role of p16INK4a Pathway in Human Epidermal Stem Cell Self-Renewal, Aging and Cancer |
Q28505604 | The Wnt receptor, Lrp5, is expressed by mouse mammary stem cells and is required to maintain the basal lineage |
Q37436067 | The cell cycle and acute kidney injury |
Q39664652 | The centrosomal protein TACC3 controls paclitaxel sensitivity by modulating a premature senescence program |
Q36911187 | The common biology of cancer and ageing |
Q26782620 | The dark side of ZNF217, a key regulator of tumorigenesis with powerful biomarker value |
Q38061186 | The genetics of type 2 diabetes and its clinical relevance |
Q28649974 | The genome landscape of the african green monkey kidney-derived vero cell line |
Q37089478 | The impact of aging on kidney repair |
Q38045210 | The long non-coding RNAs, a new cancer diagnostic and therapeutic gold mine |
Q34592870 | The microRNA 424/503 cluster reduces CDC25A expression during cell cycle arrest imposed by transforming growth factor β in mammary epithelial cells |
Q34038585 | The molecular balancing act of p16(INK4a) in cancer and aging |
Q42128558 | The novel Hsp90 inhibitor NXD30001 induces tumor regression in a genetically engineered mouse model of glioblastoma multiforme |
Q37726457 | The regulation of protein synthesis in cancer |
Q33876036 | The relationship between smoking and replicated sequence variants on chromosomes 8 and 9 with familial intracranial aneurysm |
Q26783814 | The role and mechanism of CRL4 E3 ubiquitin ligase in cancer and its potential therapy implications |
Q34341080 | The role of the RB tumour suppressor pathway in oxidative stress responses in the haematopoietic system |
Q56891289 | The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm |
Q37861625 | The tumor suppressor role of CTCF. |
Q30426400 | The yin-yang of DNA damage response: roles in tumorigenesis and cellular senescence |
Q28071309 | Therapeutic aspects of c-MYC signaling in inflammatory and cancerous colonic diseases |
Q35230162 | Thirty-five common variants for coronary artery disease: the fruits of much collaborative labour |
Q33493417 | Timed somatic deletion of p53 in mice reveals age-associated differences in tumor progression |
Q38896940 | To clear, or not to clear (senescent cells)? That is the question |
Q33510472 | Towards a systems biology approach to mammalian cell cycle: modeling the entrance into S phase of quiescent fibroblasts after serum stimulation |
Q36291101 | Transcriptional repression of CDKN2D by PML/RARα contributes to the altered proliferation and differentiation block of acute promyelocytic leukemia cells |
Q38493248 | Transcriptome analysis of neoplastic hemocytes in soft-shell clams Mya arenaria: Focus on cell cycle molecular mechanism |
Q91139907 | Transformation of mature mouse B cells into malignant plasma cells in vitro via introduction of defined genetic elements |
Q34235226 | Trithorax group proteins: switching genes on and keeping them active |
Q55056740 | Truncated Isoforms of lncRNA ANRIL Are Overexpressed in Bladder Cancer, But Do Not Contribute to Repression of INK4 Tumor Suppressors. |
Q36292997 | Tumor suppressor ASXL1 is essential for the activation of INK4B expression in response to oncogene activity and anti-proliferative signals |
Q37522773 | Tumor suppressor mechanisms in immune aging |
Q54657364 | Tumor suppressor p16 INK4a: Downregulation of galectin-3, an endogenous competitor of the pro-anoikis effector galectin-1, in a pancreatic carcinoma model. |
Q41977782 | Tumor suppressor p16(INK4A)/Cdkn2a alterations in 7, 12-dimethylbenz(a)anthracene (DMBA)-induced hamster cheek pouch tumors |
Q38266066 | Tumor suppressors in follicular lymphoma |
Q24618747 | Tumor suppressors: enhancers or suppressors of regeneration? |
Q39200828 | Tumor-specific RNA interference targeting Pokemon suppresses tumor growth and induces apoptosis in prostate cancer |
Q54330859 | UHRF1 promotes cell growth and metastasis through repression of p16(ink⁴a) in colorectal cancer. |
Q38722022 | UbE2E1/UBCH6 Is a Critical in Vivo E2 for the PRC1-catalyzed Ubiquitination of H2A at Lys-119. |
Q24310413 | Ubiquitin ligase ARF-BP1/Mule modulates base excision repair |
Q35097799 | Umbilical cord mesenchymal stromal cells affected by gestational diabetes mellitus display premature aging and mitochondrial dysfunction |
Q34031710 | Uncovering the role of genomic "dark matter" in human disease |
Q28071384 | Update on acute myeloid leukemia stem cells: New discoveries and therapeutic opportunities |
Q37748214 | Using mice to examine p53 functions in cancer, aging, and longevity |
Q33675252 | Utility of p16 immunohistochemistry for the identification of Lynch syndrome |
Q43228579 | Validation and use of a computer-assisted counting procedure to quantify BrdU-labeled proliferating cells in the early postnatal mouse hippocampus |
Q50190309 | Variants in 9p21 Predicts Severity of Coronary Artery Disease in a Chinese Han Population. |
Q49936366 | Well-Differentiated Liposarcoma (Atypical Lipomatous Tumor) Presenting as an Esophageal Polyp. |
Q98460381 | Well-differentiated liposarcoma primary from thymic stroma: Case report and literature review |
Q37599387 | Whole genome analyses suggest ischemic stroke and heart disease share an association with polymorphisms on chromosome 9p21. |
Q54400552 | YB1 binds to and represses the p16 tumor suppressor gene. |
Q39325305 | ZRF1 controls oncogene-induced senescence through the INK4-ARF locus |
Q34653709 | Zoledronic acid produces combinatory anti-tumor effects with cisplatin on mesothelioma by increasing p53 expression levels |
Q39623471 | p14(ARF) inhibits the functions of adenovirus E1A oncoprotein. |
Q45781889 | p14(ARF) methylation is a common event in the pathogenesis and progression of myxoid and pleomorphic liposarcoma. |
Q40090783 | p15Ink4b is a critical tumour suppressor in the absence of p16Ink4a |
Q36482470 | p16 Hypermethylation and KRAS Mutation Are Independent Predictors of Cetuximab Plus FOLFIRI Chemotherapy in Patients with Metastatic Colorectal Cancer |
Q50088453 | p16 Tumor Suppressor Gene Methylation in Diffuse Large B Cell Lymphoma: A Study of 88 Cases at Two Hospitals in the East Coast of Malaysia |
Q54542242 | p16 expression as a surrogate marker for HPV-related oropharyngeal carcinoma: a guide for interpretative relevance and consistency. |
Q37200881 | p16(INK4a) protects against dysfunctional telomere-induced ATR-dependent DNA damage responses |
Q21092220 | p16(INK4a) translation suppressed by miR-24 |
Q38788371 | p16(Ink4a)-induced senescence of pancreatic beta cells enhances insulin secretion. |
Q35133362 | p16INK4A and p14ARF tumor suppressor pathways are deregulated in malignant rhabdoid tumors |
Q51532861 | p16INK4A induces senescence and inhibits EMT through microRNA-141/microRNA-146b-5p-dependent repression of AUF1. |
Q24306350 | p19(ARF) deficiency reduces macrophage and vascular smooth muscle cell apoptosis and aggravates atherosclerosis |
Q39488131 | p53 binds to and is required for the repression of Arf tumor suppressor by HDAC and polycomb |
Q36890276 | p53 independent epigenetic-differentiation treatment in xenotransplant models of acute myeloid leukemia. |
Q61798614 | p53 induces senescence through Lamin A/C stabilization-mediated nuclear deformation |
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