Umbilical cord mesenchymal stromal cells affected by gestational diabetes mellitus display premature aging and mitochondrial dysfunction

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Umbilical cord mesenchymal stromal cells affected by gestational diabetes mellitus display premature aging and mitochondrial dysfunction is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1089/SCD.2014.0349
P932PMC publication ID4333320
P698PubMed publication ID25437179

P50authorYoungmi Kim PakQ87998616
Chong Jai KimQ89767788
P2093author name stringJene Choi
Jooyeon Kim
Ying Piao
Jae-Yoon Shim
Joon Seok Hong
Dalhee Chung
Eun Jeong Jun
Yu Mi Han
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p16INK4a induces an age-dependent decline in islet regenerative potentialQ28262230
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Cancer and age related colonic crypt deficiencies in cytochrome c oxidase IQ28301988
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Comparative analysis of mesenchymal stem cells from bone marrow, cartilage, and adipose tissue.Q53486333
Human mesenchymal stem cells inhibit cancer cell proliferation by secreting DKK-1.Q54498583
Derivation of Clinically Compliant MSCs from CD105+, CD24− Differentiated Human ESCsQ56915439
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Human mesenchymal stem cells as a two-edged sword in hepatic regenerative medicine: engraftment and hepatocyte differentiation versus profibrogenic potentialQ80636481
International association of diabetes and pregnancy study groups recommendations on the diagnosis and classification of hyperglycemia in pregnancyQ33683832
Review: The placenta is a programming agent for cardiovascular diseaseQ33755531
Geriatric muscle stem cells switch reversible quiescence into senescence.Q34403951
Targeted expression of catalase to mitochondria prevents age-associated reductions in mitochondrial function and insulin resistance.Q34454336
Functional comparison of chronological and in vitro aging: differential role of the cytoskeleton and mitochondria in mesenchymal stromal cellsQ34534464
The regulation of INK4/ARF in cancer and agingQ34575801
Immune properties of human umbilical cord Wharton's jelly-derived cellsQ34808849
Human stem cell aging: do mitochondrial DNA mutations have a causal role?Q35093139
Mesenchymal stem cells from rats with chronic kidney disease exhibit premature senescence and loss of regenerative potentialQ35130910
Wharton's jelly-derived cells are a primitive stromal cell populationQ35849157
Mitochondrial DNA and diseaseQ36194900
Impaired cardioprotective function of transplantation of mesenchymal stem cells from patients with diabetes mellitus to rats with experimentally induced myocardial infarctionQ36689801
Stem cells in the umbilical cordQ36712808
Placental pathology: a systematic approach with clinical correlationsQ36976570
Wharton's jelly-derived mesenchymal stem cells: phenotypic characterization and optimizing their therapeutic potential for clinical applicationsQ37007214
Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.Q37345878
Global methylation in the placenta and umbilical cord blood from pregnancies with maternal gestational diabetes, preeclampsia, and obesityQ37379816
Gestational diabetes mellitus epigenetically affects genes predominantly involved in metabolic diseasesQ37445227
Mitochondrial dysfunction of immortalized human adipose tissue-derived mesenchymal stromal cells from patients with Parkinson's diseaseQ37500329
Wharton’s Jelly Mesenchymal Stem Cells as Candidates for Beta Cells Regeneration: Extending the Differentiative and Immunomodulatory Benefits of Adult Mesenchymal Stem Cells for the Treatment of Type 1 DiabetesQ37802776
Biological mechanisms for nutritional regulation of maternal health and fetal developmentQ38022303
Umbilical cord tissue mesenchymal stem cells: characterization and clinical applicationsQ38124880
Metabolic syndrome: role of maternal undernutrition and fetal programmingQ38134314
Transplantation of mesenchymal stem cells for the treatment of liver diseases, is there enough evidence?Q38148861
Induced pluripotent stem (iPS) cells: a new source for cell-based therapeutics?Q38205616
Senescent growth arrest in mesenchymal stem cells is bypassed by Wip1-mediated downregulation of intrinsic stress signaling pathwaysQ38494140
Human umbilical cord mesenchymal stem cells inhibit C6 glioma growth via secretion of dickkopf-1 (DKK1).Q39084489
Endoplasmic reticulum stress impairs insulin signaling through mitochondrial damage in SH-SY5Y cellsQ39388001
Human umbilical cord Wharton's jelly stem cell (hWJSC) extracts inhibit cancer cell growth in vitroQ39406770
Overexpression of TFAM, NRF-1 and myr-AKT protects the MPP(+)-induced mitochondrial dysfunctions in neuronal cellsQ39487502
Bioenergetic profile experiment using C2C12 myoblast cellsQ39614847
Increasing prevalence of gestational diabetes mellitus: a public health perspectiveQ40195721
Senescence-associated lysosomal α-L-fucosidase (SA-α-Fuc): a sensitive and more robust biomarker for cellular senescence beyond SA-β-GalQ42544797
Human umbilical cord matrix stem cells: preliminary characterization and effect of transplantation in a rodent model of Parkinson's diseaseQ48730943
Potential risks of bone marrow cell transplantation into infarcted hearts.Q50685139
Morphological, molecular and functional differences of adult bone marrow- and adipose-derived stem cells isolated from rats of different ages.Q50803903
P433issue5
P921main subjectgestational diabetesQ126691
P304page(s)575-586
P577publication date2015-01-14
P1433published inStem Cells and DevelopmentQ15724421
P1476titleUmbilical cord mesenchymal stromal cells affected by gestational diabetes mellitus display premature aging and mitochondrial dysfunction
P478volume24

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cites work (P2860)
Q89291731Comparison of Preterm and Term Wharton's Jelly-Derived Mesenchymal Stem Cell Properties in Different Oxygen Tensions
Q33615119Expression of Ion Channels in Perivascular Stem Cells derived from Human Umbilical Cords
Q38873880Gestational Diabetes Affects the Growth and Functions of Perivascular Stem Cells
Q92276830Gestational diabetes impacts fetal precursor cell responses with potential consequences for offspring
Q48317686Histone Modifications Pattern Associated With a State of Mesenchymal Stem Cell Cultures Derived From Amniotic Fluid of Normal and Fetus-Affected Gestations.
Q47673849Maternal obesity and increased neonatal adiposity correspond with altered infant mesenchymal stem cell metabolism
Q37668908Mesenchymal Stem and Progenitor Cells in Regeneration: Tissue Specificity and Regenerative Potential.
Q63866082Mesenchymal Stromal Cell Characteristics and Regenerative Potential in Cardiovascular Disease: Implications for Cellular Therapy
Q38974730Sex-Specific Neurodevelopmental Programming by Placental Insulin Receptors on Stress Reactivity and Sensorimotor Gating
Q93120654Sources, Identification, and Clinical Implications of Heterogeneity in Human Umbilical Cord Stem Cells
Q46302230The current status and future of cardiac stem/progenitor cell therapy for congenital heart defects from diabetic pregnancy
Q90288589Therapeutic effect of mesenchymal stem cells derived from human umbilical cord in rabbit temporomandibular joint model of osteoarthritis
Q40054920Tissues Derived From Reprogrammed Wharton's Jelly Stem Cells of the Umbilical Cord Provide an Ideal Platform to Study the Effects of Glucose, Zika Virus, and Other Agents on the Fetus
Q28067100Umbilical Cord as Prospective Source for Mesenchymal Stem Cell-Based Therapy
Q38607615Umbilical cord-derived mesenchymal stem cell extracts reduce colitis in mice by re-polarizing intestinal macrophages
Q38731697Use of Statins to Augment Progenitor Cell Function in Preclinical and Clinical Studies of Regenerative Therapy: a Systematic Review
Q95510722[BMAL1 gene regulates the osteogenic differentiation of bone marrow mesenchymal stem cells]

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